SCROLL NEWS / DISCOVERY
Search headlines
Find the stories shaping the conversation.
Results for " manager " 1,606 found 🔀 AI-powered Shuffle
Angels fire g.m. Minasian
The Anaheim Angels fired general manager Perry Minasian on Friday
Perplexity, Kalshi, Replit insiders share how to get a startup job
We asked startup founders, recruiters, and hiring managers what to do — and not to do — to boost your chances of getting an offer.
Messi to start final Argentina group match on bench
World Cup top scorer Lionel Messi will start Argentina's final group match against Jordan on the bench, manager Lionel Scaloni confirms.
Dave Roberts Gives Update on Rushing’s Future Catching Ohtani
Dodgers manager Dave Roberts elaborated on what the plan is for catcher Dalton Rushing after his rough night with Shohei Ohtani pitching.
General manager arrested for stealing over $40,000 from Black Canyon City business
An investigation found that financial records had been deleted, documentation was incomplete and deposits were missing.
Andy Cohen cries as he mourns 28-year-old 'WWHL' producer who died of brain cancer
Andy Cohen became emotional mourning 'Watch What Happens Live' production manager Kyra Samson, 28, who died of brain cancer earlier this week.
PNC Business Credit Names Brady to Southwest Region Sales Manager
PNC Business Credit promoted Eamonn Brady to Southwest region sales manager. Based in Denver, Brady will spearhead business development efforts across both
Project manager says America’s Time Capsule is a ‘gift to the future’
The vessel will move from Washington to Philadelphia starting Friday.
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Is Yankees manager Aaron Boone’s fan survey grade fair?
Boone’s team begins a four-game set in Boston tonight.
Republic Business Credit Promotes Hebert Seghers to Vice President, Marketing Manager
Republic Business Credit promoted Katherine Hebert Seghers to vice president, marketing manager. In this role, Seghers will continue to lead the company’s
Kyle Schwarber Injury Update: Expected Return to Phillies Lineup Thursday
Philadelphia Phillies manager Don Mattingly gave an update on slugger Kyle Schwarber's injury status.
Bungie Communications Manager Says Destiny 2 fans Shouldn't Blame Themselves for Game Coming to an End
Destiny 2 fans shouldn't "blame" themselves for Bungie choosing to end support for the game, says the company's comms manager.
Florida Attorney General Issues Subpoena to CVS Health in Pharmacy Probe
Florida’s attorney general says he is examining whether CVS’s pharmacy benefit manager steers patients to its own pharmacies.
Florida AG launches investigation into CVS Health over pharmacy competition concerns
Florida Attorney General James Uthmeier issued a Civil Investigative Demand to CVS Health Corporation, the owner of the Caremark pharmacy benefit manager and hundreds of CVS retail pharmacies across the state.
2026 NHL Draft: Defensemen targets for the Penguins
Piggybacking off the earlier look into the forwards that could make sense for the Penguins to consider with the 22nd pick in Friday’s NHL draft, let’s take a turn to the blueline. Be it coincidence or preference, Kyle Dubas has only drafted one defenseman in the first round since he became a general manager in […]
Holland & Knight Health Dose: June 23, 2026 | Insights
The Centers for Medicare & Medicaid Services CMS issued a request for information RFI seeking input on implementation of new requirements for pharmacy benefit managers PBMs.
Regions Bank Announces New Leaders in Key Markets to Drive Business Growth and Customer Experience
Lisa Phillips to lead Consumer Banking in Georgia and the Carolinas; Mia Hubbard to serve as Retail Service Delivery Manager for the entire Regions branch network. Regions Bank on Tuesday announced two key leadership appointments that will drive continued business growth in vibrant Southeastern markets while also supporting consistent service enhancements at branches throughout the company’s 15-state retail banking footprint. Longtime Regions banker Mia Hubbard (top left) will serve as Retail Service Delivery Manager, and Lisa Phillips (lower, right) will succeed Hubbard as Consumer Banking Executive for Regions in Georgia and the Carolinas. Lisa Phillips will serve as Consumer Banking Executive for Georgia and the Carolinas, overseeing branch performance and growth in vital and fast-growing markets such as Atlanta, Charlotte, and additional cities across the three states. Phillips succeeds Mia Hubbard , who is taking on the role of leading Service Delivery across Regions’ entire
Man arrested 9 years after business manager killed outside Charlotte shop
The deadly shooting happened on Fugate Avenue in August 2017.
Some businesses along KC’s streetcar are making bank on the World Cup. Others not
Businesses owners and manager reported an increase in out-of-town visitors coupled with a drop in local customers.
There is belief talented McAtee will flourish at Forest
James McAtee battled to be seen in his debut season at the City Ground, struggling for minutes under Nottingham Forest's four managers. There is belief at the City Ground it is only a matter of time before it comes together for McAtee, despite his struggles. To much excitement from supporters, McAtee arrived on a five-year deal worth about £30m weeks after the under-21s' Euro 2025 triumph.
Cambridge city manager says Wu’s business summits are a ‘wakeup call’
Boston Mayor Michelle Wu has held three economic summits to address issues facing the region. Yi-An Huang has attended all three.
Gossip: Jackson hopes to remain at Chelsea
Striker Nicolas Jackson will not push for a move away from Chelsea as he aims to impress new manager Xabi Alonso in pre-season. (Football Insider)
LEECO STEEL ANNOUNCES REGIONAL OPERATIONS RESTRUCTURE
Leeco® Steel, the largest supplier of steel plate in North America, announcesthe promotion of Jeremy Rhoads to Regional Operations Manager – Texas and the tr
My 4 side gigs have made me money — and forced me to rethink my career
Jennifer Martinez, a product manager in NYC, started side hustling two years ago to create a safety net. But it's made her confused about her career.
Tunisia manager Hervé Renard reacts on the sideline
Tunisia manager Hervé Renard reacts on the sideline
Cooling hoodies help England staff combat World Cup heat
As the England players trained under the searing heat of the Kansas City sun on Saturday, manager Thomas Tuchel took a very different approach to keeping himself cool.
Jeff Lee explains why rodeo avoids politics and focuses on American values
Rodeo 250 production manager Jeff Lee discusses why the rodeo industry has largely avoided political controversies, unlike some musicians.
Springfield schools business manager: When bidding out bus fuel, it’s all about the markup
The sellers' profit margins are really what are up for bid.
'Proactive' Johansson's Motherwell appointment 'very exciting'
Former Hibernian player Kevin Nicol believes "proactive" Alfred Johansson's appointment as Motherwell manager is "very exciting". Nicol is assistant at Fredrikstad, who play in the same Norwegian top flight as Johansson's former club Rosenborg. Swede Johansson, 35, replaces Jens Berthel Askou, who became a hugely popular figure with the Fir Park faithful.
Finastra Sells Core Banking Business to Focus on Payments and Lending
Private capital asset manager Pollen Street plans to acquire Finastra’s global core banking software business, Universal Banking (UB), and support UB as
VC Nisha Dua: 'It's harder than ever to raise a fund.' Here's her advice.
Emerging fund manager Nisha Dua has weathered a fundraising winter. Now she's sharing the lessons she learned with other investors.
Lionel Messi’s family confirm father Jorge suffering from ‘health issues’
Jorge Messi has played a significant role in his son’s career, having served as his agent and business manager.
Jason Stone Joins Tepper Sports & Entertainment as General Manager of Stadium & Venue Operations
Stone will join the organization on July 8, 2026, and oversee all stadium and venue operations for Carolina Panthers (NFL) games, Charlotte FC (MLS) matches and all other events at Bank of America Stadium, in addition to TSE’s broader portfolio of venues, including Atrium Health Performance Park and the Atrium Health Training Facility.
McCarthy Aide’s Tell-All Book Recounts Trump’s Expletive-Filled Threats to G.O.P.
A new book by John Leganski, the floor manager for former Speaker Kevin McCarthy, offers a rare behind-the-scenes account of how President Trump wields his power through threats and intimidation.
Siemens Energy weighs spin-off of 'Transformation of Industry' unit, Manager Magazin reports
Siemens Energy is weighing spinning off its "Transformation Of Industry" division, which makes compressors and steam turbines, Manager Magazin reported on Thursday.
Braves' Ronald Acuña Jr. Faces Extended Recovery from Hamstring Injury
Atlanta Braves manager Walt Weiss shared an update on Ronald Acuña Jr.’s injury before Wednesday’s game against the San Francisco Giants.
Business Travel to China
In this Mobility Minute, Manager Maja Sugui provides an overview of key visa and compliance considerations for business travelers planning trips to China.
Abarca Health and LucyRx Announce Strategic Combination to Create the Only Modern PBM Built for Commercial and Government Scale
Abarca Health and LucyRx today announced a strategic combination to create the only modern, independent pharmacy benefit manager with the scale, technology, and track record to credibly serve commercial and government clients of any size. Combined, Abarca and LucyRx will provide prescription services to more than 9 million members across the United States.
Abarca Health And LucyRx To Merge Into Alternative To Big Three PBMs
Abarca Health and LucyRx - two independent pharmacy benefit managers - have agreed to merge asregulators and the public seek a better price on prescription drugs.
How Argonne’s John Domyancich is creating pathways to science, technology, engineering and math careers
STEM Learning Pathways Manager John Domyancich inspires the next generation of scientists through hands-on learning experiences at Argonne National Laboratory.
Simone Johnson Talks WWE Departure, Whether She'd Ever Return To Entertainment
Simone Johnson, formerly known as "WWE NXT" General Manager Ava, spoke about her departure from the company, and if she'd ever return to entertainment.
Gabe Halimi
Fortune Brands Innovations welcomes Gabe Halimi as its General Manager, Connect Products – Water.
Official | Hervé Renard replaces Sabri Lamouchi as Tunisia manager
Hervé Renard has been appointed Tunisia national team manager after the FTF – the Tunisian FA – opted to fire Sabri Lamouchi just one game into the 2026 World Cup, the FTF has confirmed. The deci...
Dave Roberts Grateful for Evolving Sports Culture After Attending Daughter’s Graduation
Los Angeles Dodgers manager spoke about a positive shift in sports culture after attending his daughter's college graduation on Sunday. The post Dave Roberts Grateful for Evolving Sports Culture After Attending Daughter’s Graduation appeared first on LA Sports Report.
NWA Women in Business: Melissa Curry
Residence: Fort Smith Education: Certified dementia practitioner, certified dementia practitioner trainer, certified dementia care manager, University of Arkansas at Fort Smith (Westark College) Professional background: Curry has been the CEO...
Express Scripts sues Tennessee over PBM law that would close specialty pharmacy
The company called the state’s regulation of pharmacy benefit managers “shortsighted,” as it would force the closure of Accredo, a specialty drug dispensary that supplies drugs it says aren’t available anywhere else in the state.
Damien Perrinelle set to be named Red Star manager
Former AS Monaco assistant manager Damien Perrinelle is set to take charge at Ligue 2 side Red Star, L’Équipe understands.Perrinelle, who previously managed Monaco’s academy side, was integrate...
Marc Cucurella transfer news: Real Madrid reach agreement to sign Chelsea full-back
Real Madrid have struck a deal with Chelsea for Marc Cucurella; the move is a blow to incoming Blues boss Xabi Alonso, who is already short of experienced players; Cucurella was a priority signing for new Real manager Jose Mourinho; they fought off competition from Barcelona and Man City
New York's victorious Knicks leave World Cup in the cold
The World Cup carnival arrived in New York on Saturday, but it was drowned out by the city's elation after the hometown Knicks broke a 53-year curse to win the NBA Finals.- No 'big buzz' - In an industrial section of Brooklyn, the manager of an indoor five-a-side arena said ahead of the Knicks win that "obviously the Knicks, as they should, are over-shining" the World Cup.
Shohei Ohtani sits Friday with left knee inflammation
Shohei Ohtani did not play in Friday’s series opener in Chicago after leaving Thursday’s game in Pittsburgh with left knee inflammation. Ohtani got an MRI on his left knee with showed “normal wear and tear,” manager Dave Roberts told reporters Friday in Chicago. “With the travel, just to give him an extra day. My hope […]
Vikings hire Andrew Healy, Trent Kirchner as assistant GMs
The Vikings are hiring Andrew Healy and Trent Kirchner as assistant General Managers under new General Manager Nolan Teasley, Alec Lewis of TheAthletic.com reports.
Jeffco Schools says 61 boys the Trump administration found on girls’ sports rosters were mascots, managers
Jeffco Public Schools said some girls’ teams “had male managers, trainers, or mascots — not athletes.”
'The Only Way to Keep Bungie Alive Is to Support Marathon,' Ex-Destiny Community Manager Says
As Destiny 2 fans mourn the game's final update, Bungie's former community manager has blasted players fixated on comparing its player count with fledgling extraction shooter Marathon — and said that the company's current issues began long before its arrival, as well as Sony's acquisition.
Club Science: Pride
School may be out for summer, but the Science Museum of Minnesota in Saint Paul is keeping the curiosity alive with something exciting for grown-ups. Caillean Kapoor, visitor experience manager at the Science Museum, joined Minnesota Live to share details about Club Science: Pride, a vibrant 21-plus night happening Saturday, June 13 starting at 5:30 p.m. Tickets are still available and include museum admission, an Omnitheater show and a drink ticket.
Brian Bille Appointed General Manager Of Learfield’s Mississippi State Bulldog Sports Properties
Learfield, the exclusive multimedia rights holder of Mississippi State Athletics, has announced Brian Bille as the General Manager of its locally based team,...
Dave Roberts Provides Update on Shohei Ohtani’s Injury
Dodgers manager Dave Roberts spoke about Shohei Ohtani's knee injury, which led to him leaving June 11's game vs. the Pirates.
AI boosts Lazer Logistics' efficiency in yard management
Lazer Logistics' AI tool, Uncle Phil, revolutionizes yard management by providing site managers with Phil Newsome's decades of logistics expertise.
CD&R Engages Former Enovis CEO as Operating Advisor — Clayton Dubilier & Rice, LLC
We are a global private equity manager that invests in and builds valuable businesses.
Transfer market approach and Elland Road redevelopment
Raj asked: Where do you think Leeds will strengthen this summer, and who do you think will be sold to assist financial regulations? Adam: I think there will be an attempt to retain the key talent, which has started with captain Ethan Ampadu's new four-year deal. Also, from the recent discussion with chairman Paraag Marathe, there seems a real positivity that manager Daniel Farke will be staying beyond the existing year of his contract.
New business expected to move into Franklin Foods plant after closure
The current plant manager, with the help of the state and community partners, plans to launch Franklin County Cheese at the Enosburg Falls facility
Meta layoffs hit managers, software engineers as AI spending soars
The two groups made up more than half of Meta's layoffs in California and Washington state. Meta is embracing small teams and AI tools internally.
Looming Medicaid Cuts Supercharge California’s Latest Labor-Industry Fight
One of California’s largest healthcare unions is sponsoring two initiatives that would regulate community clinics and cap executive and managerial pay at hospitals and physician groups. In the most recent eruption of a long-standing feud, the measures have drawn fierce opposition from a wide swath of the medical industry.
City Files Suit Regarding Proposed Business
The City of Greenville has filed a lawsuit in Bond County Circuit Court against the company and three individuals who proposed a sports bar/restaurant business in the former Watson’s Drug Store building on the Greenville square. Named as defendants are W.G.O. Investments, LLC, and member managers of the developer, Joseph Gira, Tim O’Donnell and Dan
We can create the future of science right now
Paul Litvak is the founder and Executive Director of the Robyn Dawes Institute and a Visiting Scholar at UC Berkeley. He has a PhD in Behavioral Decision Research from Carnegie Mellon where he studied emotions and the sunk cost bias. Over 15 years in industry, he solved a wide range of challenging technical problems. At Meta he created models optimizing the ad review process. At Google he ran experiments to measure social influence. At Airbnb, he was a product manager leading machine learning teams optimizing search ranking and price suggestions. He also co-founded and led product at Rhythmic Health, a venture-backed biosensing startup, creating an accurate low cost system using a color changing strip and a smart phone to measure salivary lactate. The bottleneck At this point, it is uncontroversial to say that science needs to stop using the PDF article as the unit of knowledge and currency. The unbearable slowness of scientific publishing, the profit motive and margins: I’m not saying anything new. The PDF also sucks because it’s hard to extract structured information, which makes it hard to do evidence synthesis. As a result, we do much less evidence synthesis than is needed. And evidence synthesis ultimately undergirds most policy and medical decision-making. I can see second-by-second real-time odds for any sporting or newsworthy event, but a school board can’t see the best evidence on whether their 8th graders should be taught algebra. As a society, we don’t treat this as an important problem. Again, not controversial. Not only is the problem well understood, but the solution has already been laid out. What we need is AI-assisted living evidence synthesis - (1) an open knowledge graph of atomic claims, (2) claims linked to evidence, (3) assessment and synthesis of each piece of evidence, and (4) continuous updating with new data. What few realize (yet) is that the technical capacity to build this vision for a significant portion of science already exists. Not only that, scientists and startup teams are already building many of these components. I know this because I’ve been surveying the space and talking to many of the builders. There are some missing pieces: for example, evaluations of how well some of the components work. But at this point, most of what’s missing is a fully end-to-end working integration of all of these parts. In the rest of this essay, I’m going to lay out all the parts of a working living evidence layer for science and who is working on them, and propose concrete next steps for building this system. What’s now possible The diagram above outlines the components of a living evidence synthesis platform, including some of the teams working on each component1. Scientific PDFs are processed into claims with associated evidence. The evidence is subjected to a forensic audit, methodological evaluation and robustness and reproducibility checks. Finally it’s given a weight in a continuously updating synthesis. What follows is a description and status of each component and a few of the teams working on them. Document understanding The first thing you need to be able to do is turn an article into structured data. Mostly that means parsing PDFs. There are often multicolumn layouts that confuse non-specialized PDF to text processing libraries. For scientific papers, there is the added complexity of parsing formulas and tables and figures. This is a really hot area - there are startups offering APIs, and it seems like a new open source package gets posted to Github every few weeks. What follows isn’t exhaustive. A package called GROBID was the state of the art for a while, they didn’t update their package for nearly two years until very recently. In the meantime reducto.ai released an AI powered PDF extraction API, PaddleOCR became popular, IBM released a model called Docling, and both Mistral and Gemini created models and libraries. I also know of at least one other well-funded psychology research group working on a paper parser. By contrast, there are few open evals in this space, with no extensive evals for complex table comprehension in particular. Nonetheless, I’m confident this will be a solved problem soon, given the combination of LLM advances and developer interest. Hypothesis level extraction There has been increasing interest in comprehending the extracted text of papers and linking information to evidence for each hypothesis. A lot of work has already been done. Trialstreamer (Marshall et al. 2020) and RobotReviewer LIVE (Marshall et al. 2023) demonstrated automated extraction of trial population, intervention, and outcome at scale on clinical RCTs. PaperQA2 (Skarlinski et al. 2024) and Ai2 ScholarQA (2024) extended this to retrieval-augmented question answering with citation grounding. Elicit, Consensus, and SciSpace operationalized claim-level extraction for end users. OpenEval (Booeshaghi et al. 2026) is the most recent and most ambitious: 1.96 million atomic claims extracted from 16,087 eLife manuscripts using Claude Sonnet 4.5, grouped into ~299,000 results, with LLM evaluations showing 81% agreement with human peer review on a 2,487-paper subset. None of these solutions link claims to test-statistics, as you would need to evaluate randomized controlled trials. This is why I built the evidence.guide API - to extract hypotheses and associated test statistics from behavioral science papers. The best public eval of this kind of extraction I’m aware of comes from the recent SCORE project - they had humans code thousands of psychology papers to extract their claims by hand. It would be extremely helpful to the world if all scientific PDFs were available as structured open data. I’ve been working to make this happen, both directly at Berkeley and through coordination with large entities I can’t yet speak of; as hard as it is to do, I think it’s possible2. Forensic audit A lot of work has been done on forensic audit, but some gaps remain. Of course, for biology papers that rely on images for evidence, there are a variety of tools (notably Proofig and ImageTwin) to spot anomalies. These are still well short of what sleuths like Elizabeth Bik can do on her own, but these tools are constant companions among fraud analysts. There’s someone working on auditing Excel files for anomalies, and a number of teams are automating numerical checks like GRIM and SPRITE, including Scrutiny project, the INSPECT-SR team as well as statcheck. The regcheck team is building a way to use AI to compare preregistrations to analyses in papers, to ensure there aren’t significant deviations. Nonetheless, there are many other kinds of anomalies to screen for, both public and less publicly known. And there are no formal evals for anomaly detection that I’m aware of. Still, there’s a lot to draw from in this space and I’m pretty certain we will be able to scan papers for most kinds of obvious anomalies in the near future. Methodological review This area has been white hot, though I fear for many of the startups in this space, because this capability may become commoditized. There are at least six different AI peer review companies, including Refine.ink, Reviewer3, ReviewerZero.ai, Q.E.D. Science, Paper Wizard, and Isitcredible. Coarse (a pun on refine) was also recently created as an open source alternative. These systems provide qualitative feedback on the content of papers, spotting methodological weaknesses and mathematical errors. They seem to work pretty well, and many academics report bitterly that they exceed the average quality of typical peer reviewers. But there are few evals here either. What evals exist so far involve using LLM-as-judge (circularity problems abound) or comparing against human reviews of questionable quality. What you’d ideally want is an eval that measures capturing known errors in papers3. Reproducibility and robustness Another active area has been using AI agents to automate computational reproducibility4 and robustness5 checks in papers that report numerical results. For more recent papers where data and code are available, AI agents can see whether they can re-run the analyses and produce the numbers reported in the published paper. In addition to a handful of individual academics who have been experimenting using Claude Code for this, the Institute for Replication is a leading group working on building an end to end system. The evals related to this problem are the most mature, with CORE-Bench (Siegel, Kapoor, Narayanan 2024) and PaperBench (OpenAI 2025) available to benchmark agents on this task. There is also work on getting AI agents to test alternative ways of analyzing the data to ensure the results are robust to small analytic design choices. Synthesis This is the most underdeveloped area where significant investment is required. Although some automated evidence synthesis systems exist — for example, otto-sr is building an AI agent to write systematic reviews — none of these incorporate the full range of paper level signals to weight evidence appropriately. Nor is there anything like an eval or a gold standard for a good systematic review. Arguably Cochrane reviews are the closest we have to gold standard human systematic reviews, though I’ve heard academics in the know complain about their uneven quality. A key question for a synthesis platform is how to weight anomalies and methodological issues in assessing the quality of a piece of evidence. This is an unsolved problem and one I’m very keen to work on. Continuous updating There are many pieces of basic infrastructure available for monitoring for new research and initiating updates. OpenAlex is the current open citation graph. Retraction Watch integrated into Crossref in October 2023. Scite tracks how citations support, contrast, or mention prior claims. The Living Evidence Network demonstrated continuous-update workflows in clinical guidelines. Engineering this is a relatively straightforward task. When you look over this technical architecture and all the progress being made, it’s hard not to be optimistic that a living guide to scientific evidence will be built. The stakeholders are ready The social infrastructure for this is starting to coalesce — it’s not just a pie in the sky academic exercise to imagine this coming into existence. Institutions like the Center for Open Science, the Institute for Replication, the INSPECT-SR, the Living Evidence Network and more are all working on scaling work to improve research quality. Funders are also aligned. The Sloan Foundation has funded living evidence work through COS. Coefficient Giving supports the Institute for Replication and COS. The Astera Institute and the Institute for Progress have shown interest in this space. NIH has established an Office for Replication and Reproducibility. Although there are (very unfortunately) serious headwinds in science funding generally, there is an active group of funders interested in metascience. A brief word about what I’ve been doing at RDI. First, as a Visiting Scholar at Berkeley I’ve been actively figuring out how a non-profit and a public university can conduct and make public the results of large-scale academic article data mining. With some of the money I raised from donors, I commissioned a legal analysis of recent case law and publisher text data mining (TDM) agreements in order to understand whether a massive open data mining of academic articles is possible (with caveats, it is). I’ve also been working to bring together stakeholders in this space, and identify gaps. I’ve also been doing some software development in this space, with more to come. A pilot proposal The assumption undergirding all of this is that an AI, given all this information, would make the right judgment about a scientific claim with lots of conflicting evidence, weighing all the factors appropriately. That’s the hypothesis we need to test. Randomized control trial research is the best place to focus on first. RCTs are used to make many of the important decisions in society - from medical trials to public policy changes. And they use a relatively uniform set of inferential statistics with lots of known and available diagnostics. Behavioral science experiments, within the broader realm of RCTs, should be first used as a testbed whose results can be generalized. Because behavioral science is at the vanguard of open science practices, replications abound (there are thousands of them) to serve as ground truth training data. Key Hypothesis Therefore the pilot would test, in behavioral RCTs that have been replicated, whether the quality of evidence for a claim can be used to accurately predict whether that claim will replicate. Secondary Hypotheses Compared to claims that replicated, non-replicated claims demonstrate a greater share of forensic anomalies in their source literatures. Hypothesis level claim and statistic extraction is accurate enough to scale living evidence without onerous human review costs. Replication prediction is more accurate than prediction markets6 or journal prestige. If all the different quality signals we gather do accurately predict which studies will replicate, then we can use that model to score evidence to power the living evidence layer. Why this is informative regardless of outcome If the pilot succeeds, the architecture extends to medical RCTs (where Living Evidence already operates and integration is mostly about claim representation), then to slices of basic biology with stable replication structure. If it fails, the field learns which quality signals are load-bearing and which ones metascience has oversold. Either result is a contribution to knowing what the literature supports. Implications for funders Because this burgeoning ecosystem of builders already exists, a well-informed philanthropic or government funder could play a crucial catalyzing role in bringing this future about. They could play at least three roles: creating open structured datasets, publishing open benchmarks and incentivizing the solving of key technical challenges. First, open archives of papers that the government maintains, like PubMed, could be turned into structured data amenable to large scale metascience and claim aggregation. I know the US government already has an interest in doing this, though some key open questions remain unanswered. How do you determine the best models and systems for accurately extracting information from papers? How can you establish a robust way to allow researchers to flag errors and correct them? And finally, how do you create a legal regime in working with publishers to maximize the scope of available papers? For the latter, a university or a private philanthropy may be better positioned to make structured data publicly available under journal subscription terms or fair use. Philanthropists or government funders could also coordinate to create or commission benchmarks that evaluate whether important problems have been solved. For example, an open benchmark for claim extraction from a range of different scientific article types would be extremely helpful. Ensuring the underlying data are accurate is vital for creating these evaluations. I’ve discussed opportunistically using various human-created datasets for this purpose, but a consistent problem is that errors in human data make it difficult for them to serve as a gold standard. Finally, with structured data and benchmarks available, the government or private philanthropy could use them to incentivize groups to develop machine learning systems that meet these benchmarks. Prizes are one potentially valuable tool for this. For example, you could establish a prize for a system that accurately updates a living meta-analysis for a small set of claims. Prizes are particularly useful as signals of problem importance, and can help create vibrant ecosystems of public and private research—see, for example the role the government played in kickstarting the current work on nuclear fusion. Conclusion The drawbacks of the current scientific publishing system are known. Scientists agree, metascientists agree, philanthropists agree: the published PDF plus citation graph isn’t the right substrate for maintaining a representation of the evidence base in science. The pieces needed to build the alternative either already exist or are rapidly taking shape. The community is forming around exactly this problem, with concrete partnerships and shared infrastructure. A pilot should start on behavioral science RCTs because that’s the slice of empirical science most amenable to legibility, where replication ground truth is richest, and where the failure modes are best documented. What’s been missing is the galvanizing mission to assemble these pieces into something that works. That’s what I’m proposing to build. *** 1 I have a broader field map that I’ll release publicly soon. This is me, building in public! 2 If this is something that you are excited about, please reach out and talk to me. 3 More on this very soon too! 4 This tests whether, given the code and the data, you can get the same statistics as reported in the published paper. 5 This tests whether the results are the same as a paper’s given alternative analytical decisions in conducting the analysis (like outlier omission). Closely related is the idea of a “multiverse” where you come up with many different ways of answering the same underlying research question with the same data, and test whether the results hold in all those alternative methods. There’s been work on the latter as well. 6 Some of the replications, e.g. those from the SCORE project, had paired the experiments with forecasts from prediction markets. So we get to look at this for free.
Wealth Managers Circle Defense Tech
In the South Bay, where venture-backed startups and legacy firms churn out in-demand military and space technology, wealth is ballooning. As some of the
Brewers' Pat Murphy Discusses Viral Jacob Misiorowski Interaction
When Milwaukee Brewers’ fire-balling prospect refused to hand over the ball, a veteran manager’s strict rules vanished. Discover how a defiant stare-down forged unbreakable trust at Coors Field.
Will Smith scratched from Dodgers’ lineup with stiff neck
Will Smith was scratched on Saturday with a stiff neck, but manager Dave Roberts said he expected him to be back in the lineup the next day for the finale of the Dodgers’ three-game series against the Angels.
Iran says U.S. has denied visas to key World Cup officials
Iran's soccer federation has accused the United States of "vindictive behavior" after saying that visas were refused for "key managerial and administrative members" of its World Cup team.
'Plenty to learn'
Northern Ireland manager Michael McArdle says "there were far too many turnovers" during his side's 2-1 defeat against Turkey in Istanbul.
I shaved my beard to try to find a job at an AI company
A tech consultant said he often faces hiring managers half his age, so he decided to send a message by changing his appearance.
Thomas Tuchel ‘concerned’ about Florida pitch
England manager Thomas Tuchel says he is “concerned” about pictures he has seen of the pitch at the Raymond James Stadium in Florida where England will play New Zealand.England play New Zealand in...
Revealed: Why Josko Gvardiol wants to leave Manchester City
World-class defender Joško Gvardiol is reportedly seeking a sensational escape route from East Manchester following the deeply impactful exit of manager Pep Guardiola.The Etihad boardroom is refusing...
Report: Arne Slot could be set for shock managerial return
Celtic weigh ambitious move for former Liverpool boss as managerial search takes fresh twistCeltic’s search for a new permanent manager could be heading in a fascinating new direction, with former L...
Scott Forbes names game one starter for super regional
UNC baseball manager Scott Forbes has named Ryan Lynch the game one starter vs. USC.
2 managers, 48 employees at Upstate business detained by ICE while working, officials announce
Two managers and 48 employees were detained by ICE for immigration violations at a business in South Carolina on Wednesday, AG says
Barcelona Reportedly Chooses And Opens Talks With Flick Replacement
FC Barcelona has chosen and opened talks with the manager it wants to replace Hansi Flick according to reports from Catalonia.
Former Viking GM Reacts to New Vikings GM Hire
New Vikings General Manager Nolan Teasley was asked at his introductory press conference Wednesday about his impressions of Vikings quarterbacks […]
Romelu Lukaku explains why he and Pogba struggled at United
Manchester United have been home to some ferocious strikers in the past, but the position has been a weak spot in the squad in the post-Sir Alex Ferguson era. The legendary Scottish manager famously s...
Entertainment 360 Hires Managers David Jimenez-Katsman And Bash Naran
Managers David Jimenez-Katsman and Bash Naran have joined Entertainment 360
Newcastle Announce Fabian Schar News After 2025-26 Season
Newcastle United have secured the future of veteran defender Fabian Schar just before his contract ended on July 1. The Mapies announced on Tuesday that the Swiss international has signed a new one-year contract through the end of the 2026-27 season, keeping him in tow under manager Eddie Howe for a ninth campaign. Schar joined […]
Brennan seeks to 'correct matters' over 12-week ban
The solicitor of Dublin senior football manager Ger Brennan says his client has concerns "a consistent and equitable approach is unfortunately not being applied to every team, player and manager" following his well-documented ban and wishes to "correct certain matters now brought into the public domain".
The Hartford to sell asset management business in deal valued at up to $1.9B
The Hartford is selling a Pennsylvania-based asset manager with about 400 employees.
Lions add former Dolphins GM Chris Grier to front office
Former Dolphins General Manager Chris Grier has found a new job in Detroit.
WhiteHawk Capital Partners Closes $390 Million Refinancing For The Star Entertainment Group
WhiteHawk Capital Partners, a private credit investment manager focused on asset-based financing solutions, announced the closing of a US$390 million senior secured financing for The Star Entertainment Group. The transaction provides additional liquidity to The Star while refinancing certain existing debt obligations.
Los Angeles Rams have the makings of a dynasty
When the Los Angeles Rams took a step back after their Super Bowl victory, many around the NFL believed they would struggle to return to contention. Some executives, including Buffalo Bills general manager Brandon Beane, even pointed to the Rams…
O'Neill over Keane a 'no-brainer' for Celtic?
Amid speculation it is now a straight fight between Robbie Keane and Martin O'Neill for the Celtic manager's job, we asked who you would like to see appointed. Henry: Stick with Martin O'Neill, if he feels he can continue. Edward: Celtic need to embrace O'Neill for one more season.
Rennes interested in €10m-rated Antoine Hainaut
Stade Rennais, after a two-year absence, will return to European football next season. With stability in the managerial and hierarchical positions, the club are already preparing for next season and, ...
Southampton sticking by manager Eckert after Spygate controversy
In its written reasons published on Monday, an arbitration panel laid bare the influence of Eckert in the scandal, saying it was “a contrived and determined plan from top down to gain a competitive advantage” and analysts who carried out the unauthorized filming “felt pressurised to do the observations that Mr. Eckert and the senior coaches wished them to do.” However, Šolak said in a video message to fans published on Tuesday that the club believes Eckert “is the man to take us forward.”
'O'Neill and Keane in battle for Celtic job'
Martin O'Neill and Robbie Keane are reportedly in a head-to-head battle to be Celtic manager as Heart of Midlothian are said to be close to signing two forwards.
Tottenham Hotspur want Fiorentina striker Moise Kean
Tottenham Hotspur manager Roberto De Zerbi has Fiorentina striker Moise Kean on his summer transfer wishlist, according to Spurs insider Szy Excl.The Tottenham Hotspur Stadium club have been discussin...
WhiteHawk Capital Partners Closes $390MM Cross-Border Refinancing for The Star Entertainment Group
WhiteHawk Capital Partners, a private credit investment manager focused on asset-based financing solutions, closed a $390 million senior secured financing for
Kevin Keegan confirms stage four cancer diagnosis as England legend issues health update
Kevin Keegan publicly shared details of his stage four cancer diagnosis during an appearance in Newcastle, as the Magpies sent their heartfelt support to their former manager
Kevin Keegan reveals stage four cancer diagnosis
Former England and Newcastle manager Kevin Keegan has revealed he has stage four cancer.Keegan twice took charge of Newcastle during his coaching career, also managing Fulham, Manchester City and England.
Official | Davide Ancelotti appointed Lille head coach
Lille OSC have announced the appointment of Davide Ancelotti to fill their managerial vacancy. Les Dogues were on the market for a head coach following Bruno Genesio’s exit, the latter is reported...
Monaghan 'put everything on the line'
Monaghan manager Gabriel Bannigan praises his side's character and spirit during their narrow 1-24 to 2-20 All-Ireland SFC first-round defeat against Mayo at Clones.
Liverpool must move for perfect Arne Slot replacement
Why Liverpool Should At Least Explore the Luis Enrique PossibilityLuis Enrique has done what very few managers in modern football have ever achieved.He has delivered consecutive Champions League trium...
NBC Sports ranks all 32 NFL GMs (see where George Paton ranks)
NBC Sports ranked George Paton/Sean Payton in the top 10 of NFL general managers.
Vikings Hire New GM — and Fans Love It
The Minnesota Vikings haven’t employed an official general manager since before the Super Bowl, firing Kwesi Adofo-Mensah on January 30th. […]