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Crimson Desert March 23 Update 1.00.03 Released

Pearl Abyss has just released Title Update 1.00.03 for Crimson Desert and shared its full patch notes.

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Mar 22 • 9:48 PM EDT • Technology • dsogaming.com
Florida basketball stunned by Iowa in March Madness Round 2 upset

Florida basketball was stunned by Iowa, ending its hopes to repeat as national champions in the Men's NCAA Tourrnament.

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Mar 22 • 9:34 PM EDT • Sports • usatoday.com
Alabama vs. Texas Tech odds, time, March Madness predictions: 2026 NCAA Tournament picks from proven model

SportsLine's model has revealed its Texas Tech vs. Alabama picks for the NCAA Tournament 2026 second-round game on Sunday

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Mar 22 • 8:03 PM EDT • Sports • cbssports.com
A promising fatty liver treatment may raise cancer risk

A surprising new study reveals that blocking a supposedly protective enzyme, Caspase-2, could actually backfire—raising the risk of chronic liver damage and cancer over time. Researchers found that without this enzyme, liver cells grow abnormally large and accumulate genetic damage, leading to inflammation, scarring, and eventually tumors, especially with age. While inhibiting Caspase-2 may offer short-term benefits, such as reducing fatty liver disease, the long-term consequences appear dangerous.

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Mar 22 • 8:00 PM EDT • Science • sciencedaily.com
Science diplomacy, research and global health

Nature Microbiology - As a young scientist from the global south, engaging in science diplomacy has brought greater purpose and meaning to my career, writes Delfina Fernandes Hlashwayo.

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Mar 22 • 8:00 PM EDT • Science • nature.com
Science diplomacy, research and global health

Nature Microbiology - As a young scientist from the global south, engaging in science diplomacy has brought greater purpose and meaning to my career, writes Delfina Fernandes Hlashwayo.

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Mar 22 • 8:00 PM EDT • Health • nature.com
Google Tested AI Headlines In Discover. Now It's Testing Them In Search

Google is testing AI headline rewrites in Search using similar language to the earlier Discover test that became a feature.

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Mar 22 • 7:44 PM EDT • Technology • searchenginejournal.com
Hackaday Links: March 22, 2026

On Friday, Reuters reported that Amazon is going to try to get into the smartphone game…again. The Fire Phone was perhaps Amazon’s biggest commercial misstep, and was only on the market…

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Mar 22 • 7:00 PM EDT • Technology • hackaday.com
Samsung Brings AirDrop Support to Quick Share with Galaxy S26 Series

Samsung is introducing AirDrop support to the Galaxy S26 series, making it easier for users to share content between devices using Quick Share. The feature will begin rolling out from March 231, starting in Korea and expanding to more regions including Europe, Hong Kong, Japan, Latin America, North America, Southeast Asia, and Taiwan. AirDrop support […]

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Mar 22 • 7:00 PM EDT • Technology • news.samsung.com
Politics, protests and popular culture: The University of Minnesota community responds to ICE impact through memes and music

Outside Coffman Union on March 3, The University of Minnesota’s Students for a Democratic Society protested Immigration and Customs Enforcement’s presence in Minnesota and on campus, despite reports that Operation...

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Mar 22 • 6:52 PM EDT • Politics • mndaily.com
Jason Momoa forced to evacuate as devastating storm hits Hawaii

Thousands have been ordered to flee as the archipelago faces its most intense surge of storms in two decades.

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Mar 22 • 6:00 PM EDT • Entertainment • yahoo.com
Women's March Madness live updates, scores: LSU makes history in NCAA tournament; Minnesota stuns Ole Miss to advance to Sweet 16
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Mar 22 • 5:19 PM EDT • Sports • sports.yahoo.com
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Cockroaches with smart backpacks? Scientists turn insects into cyborgs to detect hidden pipeline leaks

Science News: Although the concept seems like something from science fiction, science is rapidly adopting it. Researchers have started creating ‘cyborg cockroaches,.

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Mar 22 • 4:30 PM EDT • Science • timesofindia.indiatimes.com
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Arizona vs Utah State live updates: Prediction, how to watch March Madness Round 2 game

Folks were gushing about Jerrod Calhoun and Utah State's offense in Round 1. Arizona is a whole different obstacle. Follow March Madness Round 2 game.

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Mar 22 • 4:05 PM EDT • Sports • usatoday.com
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Student researchers bring Kentucky State University science to Posters-at-the-Capitol

With lawmakers just steps away, three Kentucky State University undergraduates presented research on cattle health, soil amendments and food safety at the Capitol Annex on March 5, bringing student-led agricultural […]

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Mar 22 • 3:00 PM EDT • Science • state-journal.com
Khloé Kardashian Recalls How Her Divorce from Lamar Odom Made Her ‘Obsessed’ with Leading a Healthy Lifestyle

Khloé Kardashian opened up about her relationship with diet and exercise on the March 18 episode of her podcast, ‘Khloé in Wonder Land.’ She said she became ‘obsessed’ with exercise after examining how her food choices were affecting her quality of life.

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Mar 22 • 2:30 PM EDT • Health • people.com
Florida vs Iowa live updates: Prediction, how to watch March Madness Round 2 game

Defending national champion Florida didn't need a warm-up to get going in their NCAA title defense. Will Iowa provide any resistance in March Madness?

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Mar 22 • 2:23 PM EDT • Sports • usatoday.com
Your Thymus and Your Healthspan

Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.

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Mar 22 • 2:18 PM EDT • Health • erictopol.substack.com
Politics Now: March 22, 2026

This week on Politics Now with host John Langeler: Nevada is trying to lessen its reliance on fuel from California. We talk with the vice-chair of the committee tasked with determining how to do th…

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Mar 22 • 2:01 PM EDT • Politics • 8newsnow.com
Buffalo Museum of Science celebrates 50% completion of upcoming Science Stadium Exhibit

The Buffalo Museum of Science marked a major milestone in its $3 million Science Stadium exhibit, announcing on March 20 the project is now 50% complete ahead of its planned

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Mar 22 • 1:33 PM EDT • Science • beenews.com
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Kentucky vs. Iowa State odds, time, March Madness predictions: 2026 NCAA Tournament picks from proven model

SportsLine's model has revealed its Kentucky vs. Iowa State picks for the NCAA Tournament 2026 second-round game on Sunday

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Mar 22 • 1:03 PM EDT • Sports • cbssports.com
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NCAA men's bracket live updates, scores: Purdue vs. Miami leads off March Madness Sunday; Duke, Florida, UConn return to court
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Mar 22 • 12:46 PM EDT • Sports • sports.yahoo.com
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Apple’s busy March continues with three notable arrivals this week

Apple has had a jam-packed March so far after launching seven new products and surprisingly announcing an eighth. Looking ahead,...

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Mar 22 • 11:47 AM EDT • Technology • 9to5mac.com
Messi expected to play, NYCFC vs. Inter Miami live updates

Lionel Messi and Inter Miami shift their focus to MLS play with a matchup against New York City FC at Yankee Stadium on Sunday, March 22.

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Mar 22 • 11:45 AM EDT • Sports • usatoday.com
Assemblywoman Alexandra Macedo says César Chávez allegations are "just the tip of the iceberg"

California lawmakers this upcoming week are set to move quickly to rename César Chávez Day to Farmworkers Day ahead of the holiday that takes place every year on March 31.

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Mar 22 • 11:25 AM EDT • Politics • kcra.com
Rising toll: Are NC sports betting protections enough?

With two years of legalized sports betting in the books, public health advocates, researchers and counselors suggest changes.

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Mar 22 • 9:55 AM EDT • Sports • wunc.org
Purdue vs Miami live updates: Prediction, how to watch March Madness Round 2 game

Braden Smith has the NCAA assists record, now he can focus on his main goal: a championship. Miami stands in Purdue's way in Round 2 of March Madness.

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Mar 22 • 9:44 AM EDT • Sports • usatoday.com
Apple Has Released More Than 10 Products and Accessories This Month

It has been a busy March for Apple, which has unveiled more than 10 products and accessories this month. However, aside from the all-new MacBook Neo and Studio Display XDR, the devices received faster chips or new colors and little else.

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Mar 22 • 9:00 AM EDT • Technology • macrumors.com
Oscar-Winning Alumnus Returns to Pasadena’s ArtCenter for Entertainment Design Expo

One week after winning the Academy Award for Best Animated Feature, KPop Demon Hunters co-director Chris Appelhans returns today to ArtCenter College of Design, the Pasadena campus where he studied illustration, for the college’s third annual Entertainment Design Expo. The expo, known as ENTX, opens the Hillside Campus to the public for a full day of gallery exhibitions, game playtesting, animation screenings and interactive experiences featuring work from more than 200 ArtCenter students and alumni. General admission is free with advance registration. Two industry panels — including Appelhans’s talk — require $15 tickets. Appelhans, who graduated from ArtCenter with a bachelor of fine arts in 2002, co-directed KPop Demon Hunters with Maggie Kang. The animated film, produced by Sony Pictures Animation and released on Netflix, became the streaming platform’s most-watched film in history, according to Netflix, and swept awards season with wins at the Golden Globes, the Annie Awards and the Grammys before taking the Oscar on March 15. His talk and audience Q&A is scheduled from noon to 1 p.m. in the Ahmanson Auditorium. Doors open at 11:30 a.m. The film’s ArtCenter ties extend beyond its co-director. Art director Angela Sung, cinematographer Gary H. Lee, visual development artist Celine Kim and painter Simon Baek are all ArtCenter graduates who worked on the production, according to the college. The free portions of ENTX include a concept design showcase, a production design gallery, a model gallery, a stop motion studio preview, an alumni gallery and a KPop Demon Hunters fan art gallery. Visitors can also playtest games designed by ArtCenter students. An Animation Shorts Showcase runs from 2 to 3 p.m. and includes “Boy, I’m Scared,” a capstone short by ArtCenter graduate Lindsey Tenaglia that was named a semifinalist for the 2025 Student Academy Awards in the animation category. Also screening

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Mar 22 • 8:30 AM EDT • Entertainment • pasadenanow.com
Core operating profit rises 4% as net profit holds steady, with full-year dividend maintained at HK35 cents

March 22, 2026 -- The Hong Kong and China Gas Company Limited (stock code: 0003, hereinafter referred to as “the Group”) has announced its 2025 ...

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Mar 22 • 8:07 AM EDT • Business • markets.businessinsider.com
Scientists discover surprising brain trigger behind high blood pressure

Scientists have uncovered a surprising brain-based trigger for high blood pressure, tracing it to a small region in the brainstem that normally controls breathing. This area, which kicks in during forceful exhalations like coughing, laughing, or exercise, also appears to activate nerves that tighten blood vessels—raising blood pressure. When researchers switched off this region in experiments, blood pressure dropped back to normal, suggesting it plays a direct role in hypertension.

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Mar 22 • 8:00 AM EDT • Science • sciencedaily.com
Scientists twisted a mysterious superconductor and got a shocking result

A decades-old superconducting mystery just took a surprising turn. Strontium ruthenate, a material that conducts electricity with zero resistance at low temperatures, has long puzzled scientists with hints of an exotic, complex superconducting state. But by carefully twisting and distorting ultra-thin crystals, researchers found something unexpected: the material barely reacted at all. This challenges years of assumptions and suggests its behavior may be far simpler—or far stranger—than previously thought.

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Mar 22 • 8:00 AM EDT • Science • sciencedaily.com
Margaret Cho on comedy, politics, and life in Hollywood

Comedian and actress Margaret Cho discusses her penchant for tackling political themes in her performances, evident in her upcoming tour, "Choligarchy,” coming to the Englert Theatre Friday, March 27.

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Mar 22 • 7:00 AM EDT • Entertainment • thegazette.com
Lancaster County public sales: March 22, 2026

Beiler-Campbell Auction Services conducted a public auction of real estate March 9 for Stanley and Debora Miller at 2788 N. Colebrook Road, Manheim. A four-bedroom house with attached garage and

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Mar 22 • 7:00 AM EDT • Business • lancasteronline.com
Dynamax Regice Max Monday: Event Guide

Max Monday features a different Pokémon in power spots for the whole day. Regice Max Monday takes place on March 23rd, 2026. This Max Monday is the fourth March Pokémon, and it is the debut of the legendary Ice Pokémon Dynamax Regice! Dynamax Regice is a Tier 5 Max Battle in Pokémon GO. It will cost […]

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Mar 22 • 6:11 AM EDT • Technology • pokemongohub.net
U.S. health care system is beyond repair

Letters to the editor for Sunday, March 22, 2026

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Mar 22 • 6:01 AM EDT • Health • news-press.com
White House navigates vaccine politics, midterm risks in CDC director search

The Trump administration faces complicated political dynamics as it seeks someone to helm the key public health agency suffering a prolonged leadership vacuum.

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Mar 22 • 6:00 AM EDT • Health • washingtonpost.com
White House navigates vaccine politics, midterm risks in CDC director search

The Trump administration faces complicated political dynamics as it seeks someone to helm the key public health agency suffering a prolonged leadership vacuum.

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Mar 22 • 6:00 AM EDT • Politics • washingtonpost.com
Duke vs Baylor predictions, picks, odds for NCAA Tournament Second Round

Our March Madness experts pick the winner for No. 3 Duke vs No. 6 Baylor in the 2026 women's NCAA Tournament on March 22

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Mar 22 • 5:08 AM EDT • Sports • usatoday.com
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Where to watch Minnesota vs. Ole Miss in March Madness Second Round: Time, TV Channel

The No. 4 Minnesota Golden Gophers face the 5 Ole Miss Rebels in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 22 • 5:06 AM EDT • Sports • usatoday.com
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Where to watch Duke vs. Baylor in March Madness Second Round: Time, TV Channel

The No. 3 Duke Blue Devils face the 6 Baylor Bears in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 22 • 5:06 AM EDT • Sports • usatoday.com
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Where to watch Oklahoma vs. Michigan State in March Madness Second Round: Time, TV Channel

The No. 4 Oklahoma Sooners face the 5 Michigan State Spartans in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 22 • 5:06 AM EDT • Sports • usatoday.com
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Central Mass. by the Numbers, Sunday, March 22

A look at business news in Central Mass. over the past week

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Mar 22 • 5:03 AM EDT • Business • telegram.com
49ers News: 25 more Sundays until NFL football is back

Your daily San Francisco 49ers news for Sunday, March 22nd, 2026

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Mar 22 • 4:43 AM EDT • Sports • sports.yahoo.com
How crowd-control agents can affect health

Grieving mother Naomi White walked along Kennywood Boulevard on March 15 with dozens of friends and family members who had gathered to call attention...

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Mar 22 • 4:00 AM EDT • Health • post-gazette.com
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'Education and communication key to voter turnout' in Jersey

Researcher says more work is needed to increase Jersey's low voter numbers.

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Mar 22 • 3:26 AM EDT • Politics • bbc.com
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Alaska Sports Scoreboard: March 21, 2026

Scores and results from competitions across the state.

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Mar 22 • 2:16 AM EDT • Sports • adn.com
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Things to do in Cincinnati this week, March 23-29

If you're looking for the best events happening in Cincinnati, you're at the right place. Find your next concert, game, festival or family event.

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Mar 22 • 12:15 AM EDT • Entertainment • cincinnati.com
Connections: Sports Edition today: Hints and answers for March 22, 2026, puzzle No. 545

Welcome to Connections: Sports Edition Coach — a spot to gather clues and discuss (and share) scores.

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Mar 22 • 12:00 AM EDT • Sports • nytimes.com
New Research Shows the 6 Skills You Need to Master Anything

Scientists explain why some of us benefit more than others from expert guidance.

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Mar 21 • 11:32 PM EDT • Science • outsideonline.com
Today's NYT Connections: Sports Edition Hints, Answers for March 22 #545

Here's today's Connections: Sports Edition answer and hints for groups. These clues will help you solve The New York Times' popular puzzle game, Connections: Sports Edition, every day.

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Mar 21 • 11:13 PM EDT • Sports • cnet.com
Photos: Costly error as LSU drops series to Oklahoma

An error in the eighth inning by LSU helped lead to the game winning run for Oklahoma in the final game of the series on Saturday, March 21, 2026 at

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Mar 21 • 10:40 PM EDT • Sports • theadvocate.com
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March Madness live updates, scores: No. 3 Gonzaga battling No. 11 Texas; No. 3 Illinois facing No. 11 VCU; Duke, Michigan, MSU bound for Sweet 16
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Mar 21 • 8:42 PM EDT • Sports • sports.yahoo.com
Warriors' Stephen Curry set for major checkpoint in injury recovery

According to Steve Kerr, Golden State Warriors star, Stephen Curry will participated in a scrimmage on Sunday, March 22.

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Mar 21 • 8:30 PM EDT • Sports • sports.yahoo.com
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Goodrich polishes off perfect season with MHSAA girls basketball title

Goodrich beat Tecumseh, 55-44, in the MHSAA girls basketball Division 2 state championship on Saturday, March 21 in East Lansing.

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Mar 21 • 8:24 PM EDT • Sports • freep.com
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Friction without contact discovered as magnetic forces break a 300-year-old law

Researchers have uncovered friction without contact—driven entirely by magnetic interactions. As two magnetic layers slide, their internal forces compete, causing constant rearrangements that dramatically increase resistance at certain distances. This creates a surprising peak in friction instead of a steady rise, breaking a long-standing physics law.

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Mar 21 • 8:00 PM EDT • Science • sciencedaily.com
Webb Telescope spots “impossible” atmosphere on ancient super Earth

Astronomers have uncovered surprising evidence of a thick atmosphere surrounding TOI-561 b, a scorching, fast-orbiting rocky planet once thought too extreme to hold onto any gas. Using NASA’s James Webb Space Telescope, researchers found the planet is far cooler than expected for a bare rock, hinting at a heat-distributing atmosphere above a churning magma ocean. This strange world—where a year lasts just over 10 hours and one side is locked in eternal daylight—may even be rich in volatile materials, behaving like a “wet lava ball.”

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Mar 21 • 8:00 PM EDT • Science • sciencedaily.com
Dana Walden unveils leaders of expanded Disney Entertainment

Dana Walden, the incoming President and Chief Creative Officer of The Walt Disney Company, has unveiled the new leadership structure for Disney Entertainment, bringing together the company’s streaming, film, and television businesses along with its games and digital entertainment division.

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Mar 21 • 8:00 PM EDT • Entertainment • ibc.org
More school-based health clinics fill growing needs

An increase in school-based health clinics is sweeping the states of Ohio and Michigan, following research that grounds positive health outcomes for ...

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Mar 21 • 8:00 PM EDT • Health • toledoblade.com
March Madness live updates, scores: No. 3 Gonzaga battling No. 11 Texas; Duke, Michigan, Michigan State bound for Sweet 16
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Mar 21 • 7:55 PM EDT • Sports • sports.yahoo.com
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Arkansas vs High Point live updates: March Madness Round 2 game highlights, how to watch

We're running out of Cinderellas. Will the slipper still fit for High Point? Arkansas and Darius Acuff Jr. will have something to say about that.

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Mar 21 • 7:27 PM EDT • Sports • usatoday.com
March heat wave draws Coloradans to the water, boosts seasonal business

A historic March heat wave sweeping across Colorado is sending residents outdoors in search of relief, with many trading winter sports for time on the water.

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Mar 21 • 7:19 PM EDT • Business • kdvr.com
Sanford Sports launches in Black Hills region

Sanford Sports is expanding into the Black Hills, bringing its research-backed training programs and services to athletes across the region.

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Mar 21 • 7:00 PM EDT • Sports • kotatv.com
Politics Unplugged (Full Episode) March 22, 2026

This week on Politics Unplugged, Progressive activist Kai Newkirk explains why he is running to unseat Democratic incumbent Greg Stanton in the congressional race in CD4. Then, consultants Marcus Dell’Artino and Matt Grodsky discuss the fallout from the Cesar Chavez allegations and the political importance of high gas prices.

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Mar 21 • 6:29 PM EDT • Politics • azfamily.com
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Illinois vs VCU live updates: March Madness Round 2 game highlights, how to watch

VCU's upset of North Carolina was a highlight of March Madness Round 1. What do Rams have in store for Illinois in Round 2? Follow our live updates.

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Mar 21 • 6:08 PM EDT • Sports • usatoday.com
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March Madness live updates, scores: No. 1 Duke takes on No. 9 TCU; Michigan State, Michigan bound for Sweet 16
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Mar 21 • 5:16 PM EDT • Sports • sports.yahoo.com
Google Search test replaces headlines and website titles with AI

Google Search has started testing the use of AI to replace headlines and website titles, a change that seems both...

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Mar 21 • 4:25 PM EDT • Technology • 9to5google.com
March Madness scores: Live updates, schedule for today's NCAA Round 2

Keep up with today's Men's NCAA Tournament second round with scores, highlights, game times and how to watch March Madness Round 2.

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Mar 21 • 4:15 PM EDT • Sports • usatoday.com
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Jaebri'an Autry ends Detroit Renaissance career with heartbreak

Muskegon beat Detroit Renaissance 34-29 in the MHSAA girls basketball Division 1 state championship game on Saturday, March 21 in East Lansing.

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Mar 21 • 4:00 PM EDT • Sports • freep.com
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Trump responds to Robert Mueller's death. 'I'm glad.'

President Donald Trump has responded to the death of former special counsel Robert Mueller on Saturday, March 21. Here's what he said.

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Mar 21 • 3:37 PM EDT • Politics • usatoday.com
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March Madness bracket live updates, scores: No. 3 Michigan State takes on No. 6 Louisville; Michigan routs Saint Louis
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Mar 21 • 2:45 PM EDT • Sports • sports.yahoo.com
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Salesforce (CRM) Partners with NVIDIA for AI Agents in Enterprise Business Workflows

Salesforce, Inc. (NYSE:CRM) is one of the 10 Best AI Stocks to Buy for the Next 10 Years. On March 16, Salesforce, Inc. (NYSE:CRM) announced a partnership with NVIDIA Corporation (NASDAQ:NVDA) to use its Agentforce platform and NVIDIA’s Nemotron models to bring AI agents into enterprise business workflows. This partnership connects Salesforce, Inc.’s (NYSE:CRM) Agentforce […]

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Mar 21 • 2:27 PM EDT • Business • finance.yahoo.com
Young scientists shine at Regional Science Olympiad

Budding young scientists from throughout the region participated in the 41st Annual Stanislaus County Regional Science Olympiad on March 14 at Modesto Junior College.

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Mar 21 • 2:20 PM EDT • Science • turlockjournal.com
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Scientists Recruit Undergrad to Step Into Room Filled With Ravenous Mosquitoes for “Full-Body Massacre”

Researchers at Georgia Tech used undergraduate student Chris Zuo as bait in trials to study mosquito flight behaviors.

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Mar 21 • 2:00 PM EDT • Science • futurism.com
Who is Jazzy Davidson? True freshman guard leads USC into March Madness

Jazzy Davidson leads the USC women's basketball team in every major statistical category. Now, she leads the Trojans into March Madness.

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Mar 21 • 1:31 PM EDT • Sports • usatoday.com
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UFC Fight Night odds, lines, predictions, time: Evloev vs. Murphy picks from proven MMA expert

Expert Kyle Marley reveals his UFC Fight Night best bets for the March 21 London card on Paramount+

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Mar 21 • 1:21 PM EDT • Sports • cbssports.com
High School Sports Rally: Friday, March 20, 2026
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Mar 21 • 1:21 PM EDT • Sports • cbsnews.com
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NCDHHS launches new program looking to expand number of mental health providers in state

In North Carolina, the demand for social workers in the state is growing as substance use and mental health service needs increase. The North Carolina Department of Health and Human Services launched the Public Service Leadership Program, a collaboration between the NCDHHS and 25 higher education institutions in the Social Work Coalition on NC Work Development, to help with that demand.Alongside the announcement of the new program on March 2, the NCDHHS released its first “State of North Carolina’s Mental Health and Substance Use Services Workforce Report” supported by UNC’s Behavior Health Workforce Research Center and Sheps Health Workforce NC.

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Mar 21 • 12:53 PM EDT • Health • elonnewsnetwork.com
2026 NCAA Men's Basketball Tournament Highlights: Men's Round of 32, More

March Madness continues Saturday, and we've got you covered with all the must-see moments from start to finish!

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Mar 21 • 12:11 PM EDT • Sports • foxsports.com
Hannah Hidalgo's historic season hits March Madness. What to know about Notre Dame star

Notre Dame star Hannah Hidalgo set several program, ACC and NCAA records this season. Here's what to know about the junior guard in March Madness.

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Mar 21 • 12:03 PM EDT • Sports • usatoday.com
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Particle Breakthrough: South Dakota scientists help unlock new neutrino mystery

Scientists at South Dakota Mines help achieve the first-ever measurement of a rare neutrino interaction, advancing physics and supporting future research at SURF.

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Mar 21 • 12:00 PM EDT • Science • kotatv.com
Orange County restaurants shut down by health inspectors (March 12-19)

There were 11 restaurants and food establishments ordered closed by Orange County inspectors from March 12 to March 19.

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Mar 21 • 11:27 AM EDT • Health • ocregister.com
Ranking 5 most likely March Madness upsets in NCAA Tournament second round

The second round of 2026 NCAA Tournament is underway. Here's a look at the five most likely March Madness upset predictions in the Round of 32.

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Mar 21 • 11:20 AM EDT • Sports • usatoday.com
March Madness live: Who will advance to Sweet 16? Today's schedule, TV listings

Keep up the men's NCAA Tournament on March 21, including game times, TV channels and live updates.

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Mar 21 • 10:42 AM EDT • Sports • usatoday.com
NCAA tournament live bracket updates, scores: Follow men's March Madness Saturday games with Michigan, Duke back in action
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Mar 21 • 10:17 AM EDT • Sports • sports.yahoo.com
Lauren Betts powers UCLA women's basketball in March Madness. What to know about her

Lauren Betts powered UCLA to a 31-1 record entering March Madness, and is looking to help return the Bruins to the Final Four. What to know about her.

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Mar 21 • 10:00 AM EDT • Sports • usatoday.com
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What to know about Jaloni Cambridge, Ohio State's star in March Madness

Ohio State's Jaloni Cambridge makes her presence known in the paint and with pull-up jumpers. Here's what to know about her in the NCAA Tournament.

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Mar 21 • 9:27 AM EDT • Sports • usatoday.com
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Apple TV Is Now Almost 20 Years Old

The Apple TV is now almost two decades old amid rumors of the announcement of a new model. Today marks 19 years Apple launched the original Apple TV. Apple CEO Steve Jobs unveiled the Apple TV at Macworld Expo in January 2007 alongside the original iPhone, but it didn't launch until March. The ‌Apple TV was initially previewed as the "iTV". The device allowed users to wirelessly stream movies, TV shows, music, and photos from their Mac or PC directly to their TV.

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Mar 21 • 9:14 AM EDT • Technology • macrumors.com
UFC Fight Night odds, lines, predictions, time: Evloev vs. Murphy picks from proven MMA expert

Expert Kyle Marley reveals his UFC Fight Night best bets for the March 21 London card on Paramount+

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Mar 21 • 8:46 AM EDT • Sports • cbssports.com
Duke vs. TCU odds, March Madness predictions: 2026 NCAA Tournament picks from proven model

SportsLine's model has revealed its Duke vs. TCU picks for the NCAA Tournament 2026 second-round game on Saturday

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Mar 21 • 8:32 AM EDT • Sports • cbssports.com
March Madness games today: Ranking the 16-game Women's NCAA Tournament schedule for Saturday

Syracuse vs. Iowa State and Princeton vs. Oklahoma State leads the best Women's NCAA Tournament games to watch on Saturday.

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Mar 21 • 8:24 AM EDT • Sports • usatoday.com
A massive freshwater reservoir is hiding under the Great Salt Lake

A hidden freshwater system deep beneath the Great Salt Lake has been revealed using airborne electromagnetic surveys. Scientists found that freshwater extends much farther under the lake than expected, reaching depths of up to 4 kilometers. The discovery began with mysterious reed-covered mounds formed by pressurized groundwater pushing upward. Researchers are now investigating whether this underground water could help control hazardous dust from the drying lakebed.

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Mar 21 • 8:00 AM EDT • Science • sciencedaily.com
NASA’s Hubble accidentally caught a comet breaking apart in real time

In an incredibly lucky cosmic accident, NASA’s Hubble Space Telescope captured a comet breaking apart in real time—something astronomers have long tried and failed to observe. The comet, C/2025 K1 (ATLAS), wasn’t even the original target, but when researchers pivoted to it, they unknowingly caught it mid-disintegration into multiple pieces.

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Mar 21 • 8:00 AM EDT • Science • sciencedaily.com
Front page for March 22, 26

The Spokesman-Review front page for March 22, 26

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Mar 21 • 8:00 AM EDT • Business • spokesman.com
Ancient DNA reveals a farming shift that pushed a society to the brink

A new study reveals that farming in Argentina’s Uspallata Valley was adopted by local hunter-gatherers rather than introduced by outside populations. Centuries later, a stressed group of maize-heavy farmers migrated into the region, facing climate instability, disease, and declining numbers. Despite these pressures, there’s no sign of violence—instead, families stayed connected across generations, using kinship networks to survive. The research shows how cooperation, not conflict, helped communities navigate crisis.

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Mar 21 • 8:00 AM EDT • Science • sciencedaily.com
Science news this week: Super El Niño looms, an Acropolis marble fragment resurfaces, and a pure hexagonal diamond is born

March 21, 2026: Our weekly roundup of the latest science in the news, as well as a few fascinating articles to keep you entertained over the weekend.

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Mar 21 • 8:00 AM EDT • Science • livescience.com
March Madness, Tom Brady’s Flag-Football Experiment and Jason Gay | WSJ Sports for March 21

Plus, Tom Brady’s flag-football experiment, an overturned soccer final, and Jason Gay.

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Mar 21 • 7:55 AM EDT • Sports • wsj.com
Vanderbilt's Mikayla Blakes is a scoring machine. What to know about her in March Madness

Mikayla Blakes is the fastest player in Vanderbilt history to reach 1,000 career points, hitting the milestone in 42 games.

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Mar 21 • 7:00 AM EDT • Sports • usatoday.com
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March 21 Arts & Entertainment Calendar

Events coming up in the Greenville area offer music, arts, theater and family fun. Here is a sampling. In the calendar, “today” refers to March 21.

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Mar 21 • 6:00 AM EDT • Entertainment • reflector.com
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Where to watch UConn vs. UTSA in March Madness First Round: Time, TV Channel

The No. 1 UConn Huskies face the 16 UTSA Roadrunners in the First Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 21 • 5:07 AM EDT • Sports • usatoday.com
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