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Wilmington Small Business Coalition: Building Momentum in 2026 by Heather McWhorter
This article was contributed by Lydia Thomas, UNCW CIE Program Manager. North Carolina continues to be one of the best states to start a business and in 2025, Wilmington, North Carolina earned a spot on the GoDaddy list of the top 10 most entrepreneurial cities in the U.S. While many know Wilmington as small beach town with exceptional food, lots of coffee shops, and fun, vibrant summer activities, a closer look reveals a thriving innovation economy. You’ll find startups emerging across industries including software, healthtech, bluetech, and fintech. At the core of this entrepreneurial ecosystem is the Wilmington Small Business Coalition, with small business advocates and entrepreneur support organizations (ESOs) dedicated to helping founders grow, thrive, and succeed. “No Wrong Door” Established in 2016, the Coalition was designed to make it easier for individuals and small businesses to access resources most suited to their particular needs. The Coalition is designed to have a “no wrong door” entryway into the regional startup ecosystem. Whether you are exploring a new idea sketched on the back of a napkin or leading a more established, growth-stage company, Coalition members can help connect you with the programs, funding opportunities, mentors, and resources best suited to your needs. No matter where you are in your entrepreneurial journey, any Coalition organization can help point you in the right direction. Coalition Members and Leadership Coalition members include the UNCW Center for Innovation and Entrepreneurship (UNCW CIE), AARP, Brunswick Community College Small Business Center, Cape Fear Community College Small Business Center, Cape Fear Region SCORE, Genesis Block Foundation, Network for Entrepreneurs in Wilmington (NEW), Small Business & Technology Development Center (SBTDC), Greater Wilmington Chamber of Commerce, YWCA Living the Dream Center for Entrepreneurship, Carolina Community Impact Fund (CCI Fund), Partner Community Capital, 717mkt Office Collaborative, NC Biotech, and Institute NC. In May 2026, the Coalition held its leadership elections, resulting in the selection of a new executive team. The following officers were elected to serve two-year terms: Chair: Lydia Thomas, UNCW CIE Vice Chair: Diane Lantz, CCI Fund Secretary: Aariene Hansley, Genesis Block Foundation Treasurer: Gloria Monroe, SBTDC Vision for the Wilmington Small Business Coalition In 2026, the Wilmington Small Business Coalition continues its work as a collaborative network of organizations. By connecting programs, expertise, and services across partner organizations, entrepreneurs can more easily find the right support at the right time. Rather than operating in silos, the Coalition aims to function as a unified, cohesive system of support for small businesses and entrepreneurs, ensuring that resources and expertise across partner organizations are visible and accessible. Through stronger collaboration and shared pathways, entrepreneurs can move more seamlessly from idea to startup to growth. Looking to dive into the Wilmington entrepreneurial ecosystem? Connect with any of the Coalition partners to get started! Connect with CIE To learn more about CIE and our services, programs, and events, join the CIE newsletter. You can also follow us on social media: Instagram, Facebook, LinkedIn, TikTok, or YouTube. CIE’s website is uncw.edu/cie. Heather McWhorter is the director of the UNCW Center for Innovation and Entrepreneurship (CIE). CIE supports innovation-forward start-ups and helps to build a vibrant innovation economy for all in southeast NC.
Kawhi Leonard reportedly traded back to Raptors as Clippers move on from star forward
The Kawhi Leonard era is over with the Clippers.
Jim Cramer: Honeywell’s Aerospace Business Is the “New Aerospace Play” Investors Need
Jim Cramer recently spotlighted Honeywell Aerospace (NASDAQ:HONA) on a Mad Dash segment, the newly independent aerospace company created after Honeywell Technologies (NASDAQ:HON) completed its spinoff on June 29, 2026. Cramer says he plans to own both Honeywell Aerospace and Honeywell Technologies in his charitable trust. His argument for the new Honeywell Aerospace business is straightforward: ... Jim Cramer: Honeywell’s Aerospace Business Is the “New Aerospace Play” Investors Need
UFC Power Rankings after UFC Baku
Hello everyone, and welcome back for another week of rankings in the UFC. As we look forward to no fights this week, we were definitely spoiled by the UFC Baku card. There were a few upsets, but none bigger than…
Colorado’s workers can’t afford a decline in tourism
By Terrance Carroll Work is about more than a paycheck. It is about dignity, stability and the ability to build a life, to provide for family, to contribute to community, and to move forward with purpose. That is why we should take a closer look at how federal policy decisions, even those made with good […]
ESPN Analyst Chiney Ogwumike Defends Alyssa Thomas' Behavior
ESPN WNBA analyst Chiney Ogwumike is coming to the defense of Phoenix Mercury forward Alyssa Thomas. Thomas was suspended for one game and fined for her hits on Indiana Fever guard Caitlin Clark last week. Thomas was caught hitting Clark in the groin and the neck, though she wasn't called for a ...
Netflix and Superheroes Are Having a Rough Stretch on Streaming....
(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) I have a quick prediction before we start today’s article: You might see this data in future news articles. Not my specific charts or analysis, but the core trend I’ve been monitoring—Netflix is having a lackluster Q2—will become inescapable. Often, folks want to know “What does the data say?” Well, that’s what it says. I haven’t seen this analysis hit the trades really yet, but I have a feeling some other outlets are going to start making this case soon. Remember, you read it here first. You probably have read about the problems facing superhero films at the box office this weekend. Well, this week, I explore whether superheroes are dying on TV as well! And the data says: definitely maybe! We have a lot to cover in today’s Streaming Ratings Report, which covers the two weeks of 18-May and 25-May. Today, I’m just looking at TV, like Netflix’s disappointing Q2, superhero shows underwhelming, a few TV shows dropping off the charts, The Pitt finally ending its epic run on the viewership charts (and whether “view counts” change its status as one of the biggest shows of all time), all the flops, bombs and misses, and a whole lot more. Tomorrow, I’ve got a great rundown of the film side of things. Let’s dive right in! (Reminder: The streaming ratings report focuses on the U.S. market and compiles data from Nielsen’s weekly top ten viewership ranks, Luminate’s Top Ten Data, Showlabs, TV Time trend data, Samba TV household viewership, company datecdotes, Netflix hours viewed data, Google Trends, and IMDb to determine the most popular content. While most data points are current, Nielsen’s data covers the weeks of May 18th to May 31st, 2026. You can find a link to my terminology here.) Subscribe Television - Netflix’s Q2 Slump Continues Having analyzed streaming ratings for going on half a decade, I have learned to trust my gut, but I’m always relieved when I can find actual data to back it up. For example, after a string of very popular shows like Stranger Things, Bridgerton, The Lincoln Lawyer and The Night Agent came out, week after week, in January and February, my gut wondered if Netflix had enough new and returning TV shows to sustain them throughout the year. Since then, Netflix’s post-March slate of shows has not impressed me. This week seemed to feature a potential new hit, but then, like a classic Duffer Bros. TV show, there was a twist. I speak of The Boroughs, Netflix’s latest (and last) Duffer Bros. produced show. The pitch is “Stranger Things with older actors”. And it topped the Nielsen charts: With just two weeks of viewership, The Boroughs would have been a top 25 debut show last year: But here’s the twist: Netflix has already cancelled The Boroughs! What happened? Likely a few things. First, the show didn’t do as well globally as it did in the US. As What’s on Netflix showed, it lagged behind several other shows that got cancelled. Second, its completion rate was likely low; after an initial burst of interest, it quickly dropped off on the Samba TV and Luminate charts. Third, the Duffer Bros. left Netflix for Paramount, and that may have factored into Netflix’s decision here. (Though I tend to believe that if a show is doing well, Netflix would have kept greenlighting seasons.) Still, just because I can explain why Netflix may have cancelled this show doesn’t mean I’m justifying it. In particular, as I’ve noted before, Netflix is losing a lot of their bigger shows as they reach their natural ends, and they need to replace those shows. This show had the hallmarks of a big new genre show, and it’s their biggest hit of the last few months (in the US at least), but now it’s done. Netflix’s other show this week—The Four Seasons, the second season of the “hit” show from last year—definitely disappointed. Its sophomore season had about half the viewership of the first, only 12.7 million hours. It also only had a two week run on Samba TV, and its numbers were all down on Luminate too. In other words, even with two successes, the Q2 slump for Netflix looks real: I could add to the list of disappointments: Both Lord of the Files and Man on Fire had short runs on the Nielsen charts. Running Point’s sophomore season also opened to about half its viewership, similar to The Four Seasons. A Good Girl’s Guide to Murder’s second season—see below—didn’t even make any of the three viewership charts I track, unlike the first season. Netflix is absolutely having a dismal second three months of 2026. If this Nielsen data is any indication, and I think it is, I think this will show up in Netflix’s engagement report, and maybe even their financial outcomes. And the rest of June doesn’t look much better. We have two hit shows coming back—Sweet Magnolias, one of their quietest big shows, and Avatar: The Last Airbender, a big hit for them in 2024—but the other big swings are limited series crime thrillers i.e. no future season potential. Like I said above, sometimes when I uncover a juicy nugget like this, other outlets end up writing very similar articles mimicking the data without credit. We’ll see if that happens this time! Share Television - The State of Superhero Shows on Streaming When I first heard the pitch for Spider-Noir—a Sony TV show on Prime Video that binge-released eight episodes first on MGM+ then on Prime Video two days later—I had my doubts. It’s a live-action Spider-Man show set in the 1930s, starring Nicholas Cage, based on a cameo of a character in Spider-Man: Into the Spider-Verse. No, seriously, that’s the pitch. That could either go terrifically well or horribly wrong. Great because, Spider-Man. He’s the biggest superhero we have. I’ve seen tracking numbers that put the new _Spider-Man: Brand New Da_y as the blockbuster of the year and initial pre-sales back that up. And yet this Spider-Noir pitch feels very esoteric. (Also, the eight-episode binge release feels very “Amazon copying Netflix” again.) So what’s the data say? And what does this say about the future of superhero shows?
Apple says it is releasing updates early in response to AI cybersecurity concerns
Apple said it is pushing forward a series of software updates that would previously have been bundled with a new version of its iOS operating system, making them available earlier than in previous cycles in response to AI-driven security concerns.
LeBron Reportedly Issues 'Ultimatum' To Warriors Amid Free Agency Rumors
LeBron James has reportedly issued an "ultimatum" to the Golden State Warriors amid the ongoing free agency rumors. The four-time NBA champion forward is set to hit free agency this summer. LeBron is most likely to return to the Lakers, though another team could be inching closer and closer. The ...
Copp inspires, connects with high-achieving athletes at 2025-26 Detroit High School Sports Awards
Last Wednesday, Red Wings forward served as special guest and participated in Q&A at MotorCity Casino Hotel
DF Weekly: The GTA 6 60fps Debate Returns: Is There a Route Forward on Current-Gen Consoles Like Series X, PS5 or PS5 Pro?
Or is a 40fps mode for 120Hz displays the most we can hope for?
The war against ‘woke’ could end US science as we know it
If this rule change goes forward, science in the U.S. as we know it will not exist anymore.
Conservation efforts emphasize the lesser prairie chicken
Reid DeWalt, deputy director of Colorado Parks and Wildlife, spoke to the Water Resources and Agriculture Review Committee about the Lesser Prairie Chicken and moving conservation forward. He said in 2026, CPW staff counted 77 males on 13 leks, a number that has dropped year over year since 2024. There are fewer than 1,000 chickens […]
What was it like to guard Shaq in college? ‘Glad I got him as a freshman’
Southern Miss forward Clarence Weatherspoon, who went on to play in the NBA, was the first college player to guard Shaq in a game.
Rural Fosston moves forward in its quest to relinquish control of local hospital from Essentia Health
A northwestern Minnesota community is seeking to regain local control of its hospital, arguing Essentia Health has failed to meet local health care needs. A recent court ruling allows Fosston to take its case to arbitration.
Ingredion plans global Benicaros prebiotic expansion across gut and immune health applications
Ingredion highlights that its recent acquisition of the Benicaros prebiotic is a strong strategic addition to its Healthful Solutions portfolio, supporting the company’s formulation versatility alongside expansion of health-forward and clean label ingredients. The company purchased the patented prebiotic fiber, made from upcycled carrot pomace, from NutriLeads earlier this month. With the deal, Ingredion obtained full ownership of all intellectual property, trademarks, human clinical trials, and know-how related to manufacturing Benicaros.
Lakers have interest in trading for Cameron Johnson
The Lakers are one team that reportedly has interest in trading for Nuggets forward Cameron Johnson.
Reports: Diomande agrees PSG move from Leipzig
Ivory Coast forward Yan Diomande has decided to leave RB Leipzig for Paris Saint-Germain, according to media reports. Broadcasters Sky and RMC, as well as transfer specialist Fabrizio Romano, reported on Sunday that the 19-year-old has agreed a five-year contract with the French Champions League winners.
Miles Bridges trade details: Hornets send athletic forward to Suns, land Grayson Allen
Phoenix and Charlotte kept the NBA offseason rolling on Sunday, reportedly agreeing to a deal involving some key role players.
Hornets send Miles Bridges to Phoenix Suns, AP source says
Guard Grayson Allen and forward Royce O’Neale would be coming to Charlotte, according to a person familiar with the deal.
Suns trade Grayson Allen, Royce O'Neale for Miles Bridges
The Suns have agreed to trade two key rotation players and a 2033 first-round pick for Hornets forward Miles Bridges and future draft capital.
How Ron Harper Jr. Can Impact Boston Celtics Moving Forward
The New Jersey native is set to get a new deal from the C's.
Pokémon GO Events This Week: June 29
Pokémon GO’s June 29 – July 5 week sees us enter the second month of the season of Forever Forward! We end June and kick off July with 10th Anniversary celebrations and Sobble Community Day! Plus the weekly rotating Raid Hours, Spotlight Hour, Dynamax Battles and Mega Raids. ⭐Highlights Raid Boss Change (July 1): Articuno, Zapdos, Moltres and […]
FIFA World Cup: England is coming to Atlanta
As the Group Stage concludes, Atlanta has more world-class soccer and excitement to look forward to.
The Orlando Magic Waive Defensive Versatile Forward Jonathan Isaac
The Orlando Magic severs ties with the former lottery pick to avoid a looming salary guarantee, ending an injury-plagued nine-year tenure while seeking financial flexibility for a critical offseason.
Bruins draft Russian forward with 104th overall pick
The Bruins have selected multiple Russians in a draft for the first time in almost 25 years following their fourth-round selection Saturday.
NHL Rumors: 3 Red Wings Who Could Be Traded Next
The Detroit Red Wings made a notable trade on Friday, as they traded top goalie prospect Sebastian Cossa to the Utah Mammoth in exchange for the 23rd overall pick of the NHL Entry Draft. The Red Wings then used that pick to select forward J.P. Hurlbert.Seeing Cossa get traded by the Red Wings is not […] The post NHL Rumors: 3 Red Wings Who Could Be Traded Next appeared first on HEAVY.
Rangers Land 37-Goal Star In Blockbuster Trade With Vegas
The New York Rangers have added a new star forward to their roster.According to TSN’s Darren Dreger, the Rangers have acquired forward Pavel Dorofeyev from the Vegas Golden Knights.Sportnet’s Elliotte Friedman later added that the Rangers are sending the 26th pick of the 2026 Entry Draft, the 92nd pick of this year’s draft, and their […] The post Rangers Land 37-Goal Star In Blockbuster Trade With Vegas appeared first on HEAVY.
Newsom urges a national 'billionaires' tax' while fighting one in California
The governor announced his agenda a day after an influential health care union in California pledged to go forward with a ballot measure that would impose a one-time 5% tax on the assets of billionaires living in the state as of Jan. 1, 2026. Newsom opposes that measure.
Cutting costs to move forward: SoFi State of Small business 2026 survey
SoFi reports 86% of small business owners see growth or stability, yet 66% cite high costs, mainly inflation and interest rates, as major challenges.
Cutting costs to move forward: SoFi State of Small business 2026 survey
SoFi reports 86% of small business owners see growth or stability, yet 66% cite high costs, mainly inflation and interest rates, as major challenges.
Old Town Moves Forward With Business Improvement District
City supports effort to strengthen historic district
Should “Success” in Science Be Measured Differently?
Publication volumes are one of the main ways that success is measured for researchers today. From mentorship to real-world impact, scientists argue that “publish or perish” pressures overlook many of the contributions that drive discovery forward.
Cascades doubles down on business case for sustainability
The fiber specialist laid its path forward in a 2026-2030 sustainability plan. It’s emphasizing supplier vetting and its capacity to assist customers with their sustainability goals as it continues to strive for widely recyclable packaging.
Former Illinois forward Ben Humrichous signs contract with Nets
Heading to Brooklyn.
New district leaders could take over Brooklyn Democratic Party
The current chair said she believes in "moving forward."
Tennessee court temporarily blocks state health officials from sharing undocumented ill children’s information
The “state cannot go forward with the policy” until the judge makes a final decision, said the head of the Tennessee Justice Center.
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
A new vision for quantum computing takes a big step forward, with new grant
A $4 million National Science Foundation grant will propel the next phase of a Yale-led project to build a quantum computer with an innovative new design.
Cowboys news: Dallas receiver looks forward to playing freely
Here's the latest news surrounding the Dallas Cowboys!
Propsal to limit lobbying in city of San Diego politics moves forward
The San Diego City Council’s Rules Committee voted unanimously Wednesday to direct staff to begin drafting a proposed ethics reform package aimed at lobbyists and dark money.
Primaries prove it: In New York, pro-Israel politics are now a liability
All of Mayor Zohran Mamdani's congressional picks won in Tuesday’s primaries. And they all campaigned on cracking down on the Jewish state
Colorado author shares straightforward tools for improving men's mental health
Real sign Schroeder in 'most expensive' women's transfer
BK Hacken teenager Felicia Schroeder has joined Real Madrid in a deal that makes the 19-year-old forward "the most expensive transfer ever in women's football".
Arkansas Allocates $5M for New U of A Food Science Center
A new food science research facility at the University of Arkansas is moving forward after the Arkansas Legislative Council approved a $5 m
2026 NHL Draft: Defensemen targets for the Penguins
Piggybacking off the earlier look into the forwards that could make sense for the Penguins to consider with the 22nd pick in Friday’s NHL draft, let’s take a turn to the blueline. Be it coincidence or preference, Kyle Dubas has only drafted one defenseman in the first round since he became a general manager in […]
Heartland business collecting donations for tornado victims
As the community of Mount Vernon begins to move forward, one local business is stepping up in an effort to aid those impacted by Sunday’s deadly tornado.
Are The Minnesota Timberwolves Trading For Ja Morant?
NBA fans are convinced we're going to see a backcourt of Anthony Edwards and Ja Morant next season? The Minnesota Timberwolves shocked the NBA community on Monday night by trading All-Star forward Julius Randle and the 28th pick in this year's draft to the Brooklyn Nets in a three-team deal that ...
Greece pushing for Giannis Antetokounmpo trade to Celtics
Giannis Antetokounmpo is expected to be traded to his new team before the 2026 NBA Draft starts. The Miami Heat and Boston Celtics reportedly are the finalists to land the Milwaukee Bucks forward. His home country, Greece, made its pick…
Lakewood Ranch ice sports complex expansion approved
Manatee County Commission moves forward with $80 million facility featuring four ice rinks
Palmetto Sports Shorts: The Mahaffey Legacy
WATCH: Palmetto Sports Director Carmine Gemei speaks with Clemson Men’s Basketball forward Trent Steinour about his family’s generational legacy at Clemson.
Pearl of the week: Scaling behavioral health integration
Learn how digital tools strengthen behavioral health integration.
Antoine Semenyo, Ghana's man on the inside and England threat
Antoine Semenyo knows better than most what to expect from England at the World Cup, as the Ghana forward seeks to lead the Black Stars to a surprise win over the country of his birth.Despite spending his entire life in England, Semenyo said there was no question about representing Ghana.
Kathryn Ann Meinders Digestive Health Institute Now Open, Transforming Oklahoma Healthcare
Digestive healthcare in Oklahoma took a gigantic leap forward Monday with the official grand opening of Mercy’s Kathryn Ann Meinders Digestive Health Institute.
Exclusive | DHL Set to Transport Goods on New Wind-Powered Cargo Ships
The company’s freight forwarding arm plans to carry shipments across the Atlantic on specially built sailboats.
Road to cannabis cafes is long and painful for weed businesses
Cannabis entrepreneurs have sunk lots of dollars into weed cafes, but now they're waiting for towns and state officials to let them move forward.
Katy Growth Tracker: New Restaurants, Entertainment Expansion and 348-Unit Apartment Project
Several commercial and residential development projects are moving forward across the Katy area, including new restaurants, an entertainment venue expansion and a large apartment community planned in Jordan Ranch.
Ham: Kings Likely to Retain Achiuwa Next Season
After a career-best season on a minimum deal, the versatile forward eyes a lucrative return to Sacramento following high praise from coaches and a dominant late-season scoring surge.
Where Nate Ament lands in latest mock drafts
The 2026 NBA Draft is just around the corner, and where Tennessee standout Nate Ament lands is a curious question and a storyline to follow. The 6-10 forward is a rare specimen, combining length with a variety of scoring tools, along with a capable outside shot. But so far, he hasn’t gotten the top-of-the-draft love […]
Quality experts spark change for a ‘Day of Quality’
The healthcare industry is struggling, from shortages to high demands and burnout. However, one organization is paying it forward; helping community groups help the community.
Hillsborough County to move forward with indoor sports facility at MOSI
MOSI staff said construction will take about 18 months to complete with the goal of opening in 2028.
High-Speed Rail CEO Ian Choudri on transparency, project's path moving forward
California High-Speed Rail CEO Ian Choudri is answering questions for the first time since he was put on administrative leave.
Apple to Release These 20 New Products Across Rest of 2026 and 2027
Apple's annual WWDC developers conference is in the rearview mirror, but there is still a lot to look forward to over the next year and beyond. In his Power On newsletter today, Bloomberg's Mark Gurman listed around 20 products that he expects Apple to release across the remainder of 2026 and 2027.
2026 MCWS finals: Will Oklahoma's win or UNC's loss carry more of an emotional impact in Game 2?
Instead of dwelling on a win or loss, both UNC and Oklahoma are looking forward to Game 2.
Seattle Brings Back Late Season Addition Gabrielle David
Seattle plucked Gabrielle David out of Sweden late last season, and now they're bringing back the forward full time for the next two seasons.
Three Apple Stores in U.S. Are Permanently Closing Today
As previously announced, Apple is moving forward with permanently closing three of its retail stores in the U.S. today, including a unionized location.
Forwards Kluge And Gabel Re-Join The Boston Fleet
The Boston Fleet continue to bolster their forward group re-signing Laura Kluge and Loren Gabel during free agency.
The Big Ten and SEC don’t like the college sports bill in Congress. Can they break away?
The Protect College Sports Act took a step forward Thursday with a Senate committee approval. Plenty of potential pitfalls remain ahead, including opposition from the Big Ten and Southeastern conferences.
Manchester United’s Cunha scores twice as Brazil cruise past Haiti
Manchester United forward Matheus Cunha scored twice as Brazil cruised past Haiti in Friday’s important World Cup match. The Selecao came under criticism after their lacklustre display in their ope...
USA tops Australia to clinch spot in final 32
SEATTLE — Christian Pulisic’s injury absence didn’t hurt the Americans one bit. The U.S. national soccer team found a way to advance to the knockout round without the injured forward on the field, beating Australia 2-0 Friday for its second straight victory at the largest World Cup in history. “C.P. is a fantastic player — […]
USA tops Australia to clinch spot in final 32
SEATTLE — Christian Pulisic’s injury absence didn’t hurt the Americans one bit. The U.S. national soccer team found a way to advance to the knockout round without the injured forward on the field, beating Australia 2-0 Friday for its second straight victory at the largest World Cup in history. “C.P. is a fantastic player — […]
Pelham approves $2.6 million Sports Park renovation, project comes in under budget
PELHAM, Ala. (WBMA) — Pelham city leaders have approved the next phase of improvements to the Pelham Sports Park, moving forward with a $2.6M renovation.
DOJ rebuffs judge’s request for Blanche to declare in court that anti-weaponization fund is dead
The Justice Department is rebuffing a judge’s request that it supply a court declaration from senior administration officials that would confirm that the so-called anti-weaponization fund is not moving forward.
Is PENN Entertainment, Inc. (PENN) A Good Stock To Buy Now?
Is PENN a good stock to buy? We came across a bullish thesis on PENN Entertainment, Inc. on TradersPro’s Substack. In this article, we will summarize the bulls’ thesis on PENN. PENN Entertainment, Inc.’s share was trading at $21.84 as of June 15th. PENN’s trailing and forward P/E were 77.43 and 13.14 respectively according to Yahoo Finance. […]
Is Flutter Entertainment plc (FLUT) A Good Stock To Buy Now?
Is FLUT a good stock to buy? We came across a bullish thesis on Flutter Entertainment plc on r/ValueInvesting by LowKey-Revolution36. In this article, we will summarize the bulls’ thesis on FLUT. Flutter Entertainment plc’s share was trading at $101.83 as of June 18th. FLUT’s trailing and forward P/E were 121.78 and 13.50 respectively according to Yahoo […]
Who is Gadi Eisenkot, the Israeli politician who could dethrone Netanyahu?
The former IDF chief of staff whose son was killed in the Gaza war is rapidly climbing in polls and betting markets, emerging as a leading contender to become Israel’s next prime minister.
Apple Explains Why watchOS 27 Drops Support for So Many Models
Apple today detailed why five Apple Watch models will miss out on watchOS 27 and the new Siri AI features that come with it. The Apple Watch Series 6, 7, 8, SE 2, and the original Apple Watch Ultra will not receive watchOS 27, and will only get basic security updates going forward. With the update, Apple is effectively dropping three years' worth of device support in a single software update, which is unprecedented for the product line.
What I’m Most Excited About at The Business of Beauty Global Forum 2026
Join the livestream on June 24 and 25 as we examine beauty’s current place in culture, and look forward to its new future.
Protect College Sports Act headed to Senate for full vote
The Senate Commerce Committee voted 19-9 on Thursday morning to move the Protect College Sports Act forward to a full Senate vote.
When routine business decisions become political flashpoints
5 ways to lead the way forward
Liverpool have chosen their Yan Diomande alternative forward
Liverpool are bang in the mix to sign Yan Diomande. The Ivorian, 19, is currently starring for his national team at the ongoing FIFA World Cup. And the winger emerged on Liverpool’s radar a few mont...
What smart people are saying about Kevin Warsh, the new Fed Chair
New Fed chair Kevin Warsh signaled a sweeping overhaul of the central bank, from forecasts and forward guidance to AI and operations.
Stuart Gilly on leading through uncertainty: Why moving forward is the key
In June’s episode of “Strictly Business”, entrepreneur, investor and leadership coach Stuart Gilly shared a powerful message about leading through uncertainty. His central insight is that great leaders are not defined by certainty, but by their willingness to move forward when certainty is impossible. Gilly’s leadership journey began at age 15 when he started a […]
Moving Beyond Resilience: Rebuilding the Public Health Workforce with Intention
At the Mission Critical summit, public health leaders shared forward-thinking approaches to invest in people, retain talent, and rethink how work happens.
Ole Miss infielder Brayden Randle enters NCAA transfer portal
Ole Miss infielder Brayden Randle has entered the NCAA transfer portal, On3’s Pete Nakos has learned. Randle spent three seasons in Oxford, stepping into a big-time role during the 2026 season. But Randle will be looking to spend his final year of eligibility elsewhere. Certainly a name to watch moving forward. Randle appeared in 51 […]
Planning Ahead Can Actually Make You Happier—Here's the Science Behind It
Research shows that simply having something to look forward to—big or small—can meaningfully boost your sense of well-being.
Schumer bill to permanently end 'Anti-Weaponization Fund' fails
Acting Attorney General Todd Blanche has said the DOJ would not move forward with the fund, but he has not put it in writing
Schumer bill to permanently end 'Anti-Weaponization Fund' fails
Acting Attorney General Todd Blanche has said the DOJ would not move forward with the fund, but he has not put it in writing
Dragon Undocks to Return Science Experiments to Earth
At 12:25 p.m. EDT, the unpiloted SpaceX Dragon spacecraft undocked from the forward‑facing port of the International Space Station’s Harmony module after a command from SpaceX ground controllers. Flight controllers delayed the undocking slightly to power‑cycle a navigation sensor and restore full redundancy before departure.
These forward-looking, early-stage businesses are already standing out
The World Changing Ideas On the Rise honorees are tackling issues like accessibility, climate change, and more.
Baker leaders, BREC propose multimillion-dollar investment in youth sports facilities
City leaders and BREC officials are moving forward with plans to invest millions of dollars into youth sports facilities in Baker.
Mercy's Kerry Bommarito Earns "Top Women in Health IT" Recognition Again
Behind every breakthrough in healthcare technology is a leader helping move care forward — like Mercy’s own Kerry Bommarito. Mercy’s vice president of enterprise AI and decision intelligence has again been recognized by Becker’s Hospital Review, this time as part of its 2026 list of “Women in Health IT to Know.”
5 most intriguing non-division games on the Cowboys schedule
What non-division game are you looking forward to the most?
Business Associates Face Increased Regulatory Scrutiny as Vendor Breaches Soar
The healthcare industry has the highest rate of third-party data breaches out of any sector, according to the Verizon Data Breach Investigations Report In 2017, 13% of healthcare data breaches involved healthcare vendors. Fast forward to H1 2026, and that percentage has risen to 43%. With data breaches soaring, vendors are facing increased regulatory scrutiny, and new cybersecurity requirements are due for imminent release.
💪 Dream World Cup debut! Gyökeres is making history tonight
The Swedish forward is destroying any trace of nerves in his World Cup debut. In less than sixty minutes, he delivered his first assist and scored his first goal in football’s biggest competition. ...