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The Best Anti-Meta Smart Glasses Are About to Have Tough Competition
If camera-equipped smart glasses aren't your thing, you're about to have a new pair at your disposal.
Globe unveils new business newsletter
There’s no pair of journalists better suited to give you the scoops, inside gossip, and analysis on the local business scene.
New Research Brings Joint Repair Closer for Millions With Osteoarthritis
DURHAM, N.C. — Osteoarthritis affects more than 32 million Americans, making it one of the leading causes of chronic pain, disability, and loss of mobility in the United States.For many people, treatment options are limited to managing pain with medications or repeated injections, and in severe cases, replacing the joint entirely through surgery.
Porsche Teases New 911, Could Be A Drop-Top GT3
A new 911 is on the way, and early clues suggest it could pair GT3 hardware with a convertible twist
CAA Softball Weekly Awards
RICHMOND, Va. – UNCW’s Allison Corbin and Hofstra’s Ryleigh Smith captured CAA Player and Rookie of the Week honors, respectively, while a pair of complete-game shutouts from both the Pride’s Emma Falen and Campbell’s Katelyn Hubley split Pitcher of the Week recognition, respectively, on Monday.
Inside the Rays’ new era: A Q&A with Ken Babby on Opening Day, fans and what’s next for a new ballpark
'Fans can expect our organization to be determined, accountable and accessible, as they should.'
Google Pixel 10a disassembly nets it a very good repairability score
You can see the whole process in this video. Google launched the Pixel 10a in February and released it in early March, and today a video showing its...
Denver fans celebrate sports-filled Saturday at Stoney's with pair of thrilling victories
Colorado Avalanche and Denver Nuggets fans packed Stoney's Bar and Grill on Lincoln to celebrate a pair of thrilling victories on Saturday.
Laie business seeks community help after flood damages thousands of pairs of slippers
J-Slips Hawaii faces heavy losses from Kona Low flooding and calls on volunteers to help clean and restore affected inventory.
Oregon rallies late to take down Michigan, snap losing skid
After a pair of shutout losses, Oregon bounced back to tie the series on the diamond in Ann Arbor against Michigan.
Tarrytown spa undergoing repairs after SUV crashed into business
Repairs are underway at a Tarrytown spa after an SUV crashed into the business. The business hopes to reopen in early May.
Local garage door repair business, customers targeted by nationwide scam
Fallout from a nationwide trend of garage door repair scams showed up at the doorstep of Ray and Brad Larson in the form of angry customers they never heard of.
Relationship with Trump may be beyond repair, Keir Starmer told
PM gets widespread backing after president’s mocking impersonation takes US-UK relationship to new low
Spoiler Alert! Devils Rout Caps Behind Bratt, Hughes
Look at the Devils delivering maximum damage to a pair of Metropolitan Division rivals this week, although in very different ways. First, on Tuesday, they rolled over and played dead for a hapless Rangers team that got two points that won’t help them in their race to the bottom for Gavin McKenna. Forty-eight hours later […]
2026 NFL mock draft 7.1: Jeremiyah Love, pair of Buckeyes go top-5 as attention turns to April
Scientists discover hidden “winds” inside cells that could explain cancer spread
Cells aren’t as passive as scientists once thought—they actively create internal currents to move proteins quickly and efficiently. These “cellular winds” push materials to the front of the cell, enabling faster movement and repair. Discovered by chance and confirmed with advanced imaging, this system challenges decades of textbook biology. It may also reveal why some cancer cells spread so rapidly.
Juanjo Duran, Global Head of Media & Entertainment Content Partnerships at Google
Juanjo Duran, Global Head of Media and Entertainment Content Partnerships at Google tells ADWEEK the two things he knew early on in his career: he loved technology, and he loved building relationships. What he didn’t expect was how that pairing would fuel a 15‑year career shaping how billions of people access entertainment.
2026 NFL mock draft 7.0: Jeremiyah Love, pair of Buckeyes go top-5 as attention turns to April
Back to Business Program helps Quynh’s Pharmacy continue serving Little Saigon community
Quynh’s Pharmacy is a fixture in Little Saigon. The owner, Mary Bui, is also a fixture within the pharmacy, having worked there for three decades. When vandals broke the glass entry door and both security gates, Bui faced a steep bill to repair the damages. “They charged over $6,000,” she explained. “We had to do […]
Bang & Olufsen adds to its super-high-end, super-exclusive series of limited edition speakers
But only 10 pairs are available
Samsung's new app temporarily cures motion sickness through earbuds
You can use the Galaxy Buds4 Pro, or any other pair. Samsung has launched a new Android app that can work with its Galaxy Buds4 Pro to temporarily rid you...
College baseball rankings, polls after Week 6: UCLA leads as top 10 gets shuffled
UCLA remains No. 1 in the USA TODAY Sports baseball poll, but the top 10 got a new look with a pair of SEC teams tumbling down the rankings.
Better Business Bureau warns of spring and summer scams targeting homeowners
The BBB's scam tracker shows some New Yorkers have lost nearly $12,000.
Weizmann Institute rebuilds after Iranian missile strike, but lost science may be gone for good
Most buildings damaged in the June 2025 attack have been repaired, but destroyed research and data cannot be recovered.
4 Devices Your DualSense Controller Can Connect To (Other Than Your PlayStation 5)
Your DualSense can connect to PCs, Macs, mobile devices, smart TVs, and the Steam Deck. Here's how to pair it and which features work on each.
Cory Booker says Democrats have 'failed this moment,' need new leaders
In an interview, the New Jersey senator said his party needs a \
Floyd Mayweather reveals Manny Pacquiao rematch will be an ‘exhibition’
The pair are set to resume their rivalry in September but Mayweather has cast doubt on whether this bout will be his return to professional boxing
DHS shutdown drags on after House passes 'dead on arrival' bill
The House-passed bill is doomed in the Senate, which is on a scheduled recess.
Popular sugar substitute linked to brain damage and stroke risk
A widely used sugar substitute found in everything from keto snacks to diet drinks may not be as harmless as it seems. New research shows that erythritol can disrupt brain blood vessel cells, reducing their ability to relax, increasing harmful oxidative stress, and impairing the body’s ability to break down clots. These changes create conditions that could raise stroke risk, even at typical consumption levels.
Understanding protein motion could greatly aid new drug design
For many of us, “protein” is the key element of a food order. However, beyond your preferred choice of meats or plant-based alternatives, proteins encompass a large class of complex biomolecules whose chemical structure is encoded in our genes. Proteins have critical functions in living cells: They help repair and build body tissues, drive metabolic reactions, maintain pH and fluid balance, and keep our immune systems strong.
"We were there in the 80s for the crash, and this is definitely crashier." John and Brenda Romero reflect on the industry crisis
The pair have had to dramatically downsize their studio since the money dried up – but they're determined to keep on coding to the bitter end
Here’s how to rank the 50 best Apple products ever
With more than 1,200 possible pairings, which product will come out on top?
Google Gemini now lets you import your chats and data from other AI apps
Google is adding a pair of new features to Gemini aimed at making it easier to switch to the AI chatbot.
The Tampa Bay Rays juggle roster moves, stadium politics and new fan perks ahead of Opening Day
The Rays return to Tropicana Field under a new roof on April 6.
The Fake Cartier and the Fake Rockefeller
How a pair of blue-blood impostors turned party crashing in the Hamptons and Palm Beach into a business.
Consumer Sleep Technology Can Support Better Sleep, With Limits
A commentary Miller School of Medicine researchers underscores that pairing sleep and exercise may produce greater health benefits.
Should computer science be compulsory in Ohio schools?
Currently, twelve states in the US are phasing in requirements for students to complete a computer science course before graduating high school. Should Ohio become the 13th state? That is what a pair of bills in the Ohio Statehouse are proposing to do.
Accrington Victoria Hospital site to become health and care hub
Accrington Victoria Hospital closed in 2024 after the building was found to be beyond repair.
Scientists say NAD+ could slow aging and fight Alzheimer’s and Parkinson’s
A global team of leading scientists is zeroing in on a tiny but powerful molecule that could reshape how we age. Known as NAD⁺, it plays a crucial role in keeping our cells energized, repairing DNA, and maintaining overall health—but its levels steadily decline over time, potentially fueling diseases like Alzheimer’s and Parkinson’s. Researchers are now exploring ways to boost NAD⁺ using compounds like NR and NMN, with early studies hinting at improvements in memory, metabolism, and physical function.
Why Wall Street seems to keep believing Trump
If you’ve been paying attention to, like, the news, you may be tempted to see Wall Street’s Monday morning 180 from despair to euphoria as a sign that stock traders are all a bunch of rubes.
Exclusive | Lawmakers to Introduce Bipartisan Bill Banning Sports Bets on Prediction Markets
A bipartisan pair of U.S. senators are introducing legislation to prohibit CFTC-regulated entities from listing contracts related to sporting events.
St. Louis Blues Weekly Prospect Report (March 22)
Jiricek has big scoring week; McIsaac announces future plans; Ralph, Michigan State head to NCAA Tournament with Mayich, Clarkson University eliminated; Peterson scored pair, including a SH beauty for Springfield
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
U.S. health care system is beyond repair
Letters to the editor for Sunday, March 22, 2026
Panthers make pair of returns official
The returns of two Panthers were announced on Thursday.
10 tried-and-true methods to stay off your phone, according to our readers
We asked our audience to share the creative ways they limit their own phone use. They range from the practical (keep your phone in another room) to the creative (pair your phone with a fun paperback).
Vehicles damaged in West Allis car wash; business to pay for repairs
Four people say their vehicles were damaged at the Tsunami Express Car Wash in West Allis on Feb.10. They told Contact 6 their vehicles were scratched and two cars' back windows were smashed.
Even humans love a good mating call
Volunteers listened to animal mating calls and played a computer game—for science.
Your NCAA Basketball Tournament Viewing Guide: March 19, 2026
Not just the 16 first round games on the men’s side, but the second pair of First Four games on the women’s side as well!
Customers help Denver small business owner relocate after 60-day vacate notice
Denver electronics repair business receives support after being force to leave workshop
Philadelphia Eagles' dynamic duo named one of NFL's best
The Philadelphia Eagles' dynamic receiving duo of A.J. Brown and DeVonta Smith was recently named one of the best in the entire NFL by Moe Moton of Bleacher Report. The pairing of Smith and Brown was named as the fifth-best wide receiver duo in the league, behind Ja'Marr Chase and Tee Higgins in Cincinnati, Puka Nacua And Davante Adams in L.A., CeeDee Lamb and George Pickens in Dallas and Amon-Ra St. Brown and Jameson Williams in Detroit.
Kristin Cabot gives update about former boss after viral Coldplay kiss cam
Kristin Cabot has her sights set on the future, one that does not include former Astronomer CEO Andy Byron. Here's where the pair stands.
iFixit Tears Down the iPhone 17e, Discovers MagSafe Upgrade Path for iPhone 16e Owners
Repair site iFixit today took apart the iPhone 17e, which is the new low-cost iPhone that Apple launched last Wednesday. The iPhone 17e is almost identical to the iPhone 16e in design, but it does include a MagSafe back panel that supports MagSafe and faster Qi charging than the iPhone 16e. When disassembling the iPhone 17e, iFixit found that the MagSafe panel for the device is the same size as the panel for the 16e, and the two are interchangeable.
OPPO Find N6 - Ultra Flat, Flexible & Powerful
Discover the OPPO Find N6: foldable flagship featuring Zero-Feel Crease and 200MP Hasselblad Camera. Paired with OPPO AI Pen, unleash your creativity.
Democrats like Markwayne Mullin but that doesn’t mean they’ll vote for him for DHS secretary
In his early days in Congress, Markwayne Mullin tried pairing his suit jacket and tie with a pair of jeans on the House floor. Then-House Speaker John Boehner reprimanded the young Republican for breaking the dress code.
Pair accused of operating fake contracting businesses in Lower Merion Township
Police in Lower Merion Township are looking to identify further victims of an organized fraud scheme involving fake contracting businesses.
Volvo Construction Equipment announces closure of Rokbak business
As part of a long term strategic shift and due to the unsustainable profitability of the Rokbak business Volvo Construction Equipment (Volvo CE) will close its Rokbak business and concentrate resources on its portfolio of other hauling solutions. The business had revenues of SEK 1.0 bn in 2025 and was loss-making. The closure of the business will negatively impact operating income by about SEK 0.7 billion in the Construction Equipment segment in Q1 2026 and will be reported as an adjustment. About SEK 0.4 billion refers to non-cash items with the majority related to goodwill impairment.
Recently unbeatable, UMBC and Howard clash in First Four
DAYTON, Ohio -- The field of 68 teams in the 2026 NCAA Tournament begins to get whittled down Tuesday night when a pair of No. 16 seeds from the Midwest Region square off.
Kennedy Center votes to shut down operations for 2 years and names a new president
The widely expected decision comes in the wake of numerous resignations and cancellations during President Donald Trump's second term, although Trump himself has cited the need for repairs as a reason for the closure.
Rare blower RTX 5090 AI card repaired by cutting memory from 32GB to 28GB
Brother Zhang fixes AI RTX 5090 card by cutting memory-bus An interesting card, and an interesting fix. This RTX 5090 for AI was made at your gaming
What Zootopia 2 gets right about the science of snakes
At its core, Zootopia 2 is a defense of snakes. The Oscar-nominated sequel to Zootopia centers on an unlikely pair of animal police officers—Judy Hopps, a rabbit, and her fox partner, Nick Wilde—who ...
Wisconsin sets official visits with two class of 2027 lineman
A pair of lineman have set visits with the Wisconsin Badgers. Both are Class of 2027 recruits, though neither are in-state targets.
This Printed Zipper Repair Requires No Unsewing
If a zipper breaks, a 3D printer might not be the first tool one reaches for — but it’s more feasible than one might think. [MisterJ]’s zipper slider replacement is the kind of 3D…
Scientists discover ALS protein that links DNA repair to cancer and dementia
A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that TDP43 controls a key DNA repair process, but when the protein becomes imbalanced, the repair system can spiral out of control, harming neurons and destabilizing DNA. The team also discovered that high levels of the protein are linked to increased mutation rates in cancer. The discovery places TDP43 at the center of both neurodegeneration and cancer biology.
Officers searching for two people who robbed Hopewell business
Officers said the pair held the employee at gunpoint.
The MacBook Neo is ‘the most repairable MacBook’ in years, according to iFixit
Apple’s new MacBook Neo isn’t just the most affordable MacBook — it’s also the company's most repairable laptop in “about fourteen years."
Apple MacBook Neo emerges as company’s most repairable laptop in more than a decade
Apple's MacBook Neo, the laptop it announced last week that starts at $499 for students, is the most repairable laptop the company has released since 2014, according to an analysis released Friday by iFixit.
Trump signs executive orders aimed at home affordability ahead of midterms
President Donald Trump on Friday signed a pair of executive orders aimed at showing his commitment to improving home affordability — a key issue for many voters going into November’s election for control of the House and Senate.
April 1 Is Next Possible Launch Date For Moon-Bound Mission Following Repairs
The space agency has updated the list of the next possible launch dates.
First MacBook Neo teardown praises 'absolutely amazing' repairability
"No sticky tape, no tricky adhesives, modular parts... it's just super straightforward, elegant design."
MacBook Neo Teardown: Modular Ports, Glue-Less Battery, Zero Tape
A teardown of the new MacBook Neo by Australian YouTube repair channel Tech Re-Nu reveals what may be the most modular and repair-friendly Mac laptop in recent times. The Neo is shown being taken apart in just six minutes, suggesting Apple has prioritized simplicity across the board, using standard Torx screws (T3, T5, and T8) and a clean cable routing design. To open the aluminum body, eight screws on the bottom are loosened, similar to the MacBook Air and MacBook Pro.
Torrent Come From Behind To Beat First Place Boston
The last place Seattle Torrent beat the first place Boston Fleet erasing a pair of deficits to snap a four game losing streak.
Bills’ updated 2026 NFL Draft picks following pair of trades
The Buffalo Bills finalized two trades at the start of the 2026 new league year, bringing in AJ Moore, and parting way with Taron Johnson.
Dolphins re-sign pair of defenders as free agency opens
The Miami Dolphins had several players hitting the market when the new league year officially started, but they kept two late Tuesday afternoon.
A roadside emergency leads to a happy ending — and a new friendship
A Temple Health nurse and a pair of Pennsylvania Turnpike workers saved the life of a driver who was in cardiac arrest late last year. They have since bonded.
Universe-shaking collision of black hole and neutron star could upend our understanding of monster cosmic mergers
The catastrophic collision of a black hole and a neutron star sent ripples across the universe. New analysis of those ripples could upend a major theory about how these extreme pairs form.
Here’s how much a MacBook Neo repair will cost you
If you’re considering buying the new MacBook Neo, whether for yourself or a family member, it may be helpful to know how much repairs will cost.
Class B: 2026 boys and girls state basketball scores and pairings
Updated scores and pairings from the 2026 Class B boys and girls state basketball tournaments in Billings.
ESPN Makes Bold Predictions for Washington Nationals in 2026
ESPN preidcts a pair of Washington Nationals stars all be able to address key weaknesses during the 2026 season
High school basketball: Southern California regional scores and pairings
CIF Southern California regional high school boys' and girls' playoff scores for Saturday and Tuesday's schedule.
High school soccer: Southern California regional final scores and state pairings
CIF Southern California regional final high school boys and girls soccer scores and state championship schedule.
In Russia’s Former Capital, Restoring the Past to Survive the Present
With political activism off-limits, residents of St. Petersburg are finding purpose and community in the “politics of small deeds,” repairing and cleaning architectural treasures.
No. 9 Nebraska looks to avenge loss vs. Iowa
A pair of Big Ten men's basketball teams seek to end recent on-court disappointment when Iowa travels to Nebraska for a conference regular-season finale Sunday.
Northwestern strives to finish strong vs. Minnesota
A pair of teams will look for a boost heading into Big Ten tournament play when Minnesota tips off against Northwestern on Saturday night in Minneapolis.
'It was a deal': Bellingham native buys Pacific Science Center's stegosaurus head for thousands
A Bellingham native invests in the Pacific Science Center's stegosaurus head as the dinosaur exhibit faces closure and disrepair.
St. Peter's announces closure of Albany nursing home
The closure of the facility after nearly seven decades is the result of the building needing tens of millions of dollars in repairs, the health network says.
Scientists create cartilage scaffold that helps the body regrow bone
Researchers in Sweden have engineered a cell-free cartilage scaffold that can guide the body to rebuild damaged bone. By removing the cells but preserving the structure and natural growth signals, the material acts as a blueprint for the body’s own repair process. In animal studies, it helped regenerate bone without triggering strong immune reactions. The team now plans to scale up production and begin testing the approach in humans.
Hochul meets with Trump's ‘border czar’ in Albany
The pair talked face-to-face for an hour, according to a Hochul spokesman.
Scientists Just Took One Big Step Toward an Unhackable Internet
A quantum internet is only as useful as its reach, and in a first, researchers created more than a million qubit pairs across 100 kilometers of fiber.
High school soccer: Southern California regionals scores and pairings
CIF Southern California regional high school boys and girls soccer playoff scores and schedule.
High school basketball: Southern California regional scores and pairings
CIF Southern California regional high school boys' and girls' playoff scores for Thursday and Saturday's schedule.
Cracker Barrel Works to Repair Its Business
Cracker Barrel reported lower profits and revenue in its latest quarter, but its CEO said efforts to turn around the restaurant chain are taking shape.
The Jets are considering two veteran starting quarterbacks per reports
The Jets need to find a starting quarterback in 2026. There aren’t many quality options on the market. However, over the last few days a pair of teams announced they were moving on from big money veteran starting quarterbacks. The Cardinals are parting ways with Kyler Murray after seven years, while the Dolphins are doing […]
First M4 iPad Air Benchmarks Surface
Ahead of the launch of new iPad Air models equipped with the M4 chip, preliminary Geekbench benchmark results have surfaced for the device, giving us an idea of how its performance compares to the prior-generation M3 iPad Air. A pair of benchmarks from the 13-inch M4 iPad Air with Wi-Fi + Cellular (iPad16,11) suggest the M4 iPad Air CPU is 17.3 percent faster in single-core performance and 7.9 percent faster in multi-core performance.
Jasmine Crockett or James Talarico? Democrats Don’t Have an Easy Answer, But They Do Have a Clear One.
The party clearly needs a new path forward, and the Texas duo offers a pair of visions that are compelling—and competing.
Medical journal The Lancet blasts RFK Jr.’s health work as a failure
Kennedy's destruction "might take generations to repair," The Lancet said.
What Is That Mysterious Metallic Device US Chief Design Officer Joe Gebbia Is Using?
Gebbia was reportedly spotted at a San Francisco coffee shop using an unidentified pair of earbuds with a circular disc that looks similar to the device seen in a recent OpenAI hoax ad.
Dolphins update Liam Eichenberg, Ethan Bonner status for 2026
The Miami Dolphins announced a pair of roster moves on Monday, including releasing a former second-round pick.