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Week 5 changes the picture for college football’s undefeated teams

Week 5 reshaped the college football landscape as several undefeated teams suffered their first losses. Alabama, Georgia, Notre Dame and Miami strengthened their playoff cases, while Texas remained No. 1. With 15 unbeaten teams left, Week 6 brings crucial matchups that could dramatically reshape the national championship race.

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Oct 7 • 7:30 AM EDT • Sports • sports.yahoo.com
Tuchel's England 2.0: what has changed?

Since the World Cup Thomas Tuchel has made deliberate changes in both tactics and personnel. So what has he tweaked as he looks to refine his England blueprint rather than rewrite it from scratch?

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Oct 7 • 7:06 AM EDT • Sports • sports.yahoo.com
Arctic Wolf CEO: AI Has Changed Cybersecurity Forever

Arctic Wolf CEO Nick Schneider joins the Twin Cities Business Show to talk about how artificial intelligence has fundamentally changed cybersecurity. According to Schneider, we are already past the point where humans can defend against agents, and need agents of their own to keep themselves safe. Schneider explains how AI is giving cybercriminals new capabilities,

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Oct 7 • 6:47 AM EDT • Business • tcbmag.com
‘A tsunami and an earthquake’: Rural health care braces for Medicaid cuts

North Shore Health and other health care providers are bracing for the effects of H.R. 1, also known as the One Big Beautiful Bill Act. Changes to Medicaid from the new law are being phased in over several years, with some provisions extending into 2028. In Minnesota, however, some eligibility restrictions took effect Oct. 1....

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Oct 7 • 6:11 AM EDT • Health • wtip.org
MORNING BUSINESS REPORT: McDonald's accused of AI-powered price fixing, Uber enters the catering business

Jane King has these stories and more from the New York Stock Exchange for your Wednesday Morning Business Report.

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Oct 7 • 6:06 AM EDT • Business • wfsb.com
More health claim denials will hurt patients and clinics

A measurable change is seen in the financial system supporting care. Data shows claim reductions and denials have increased by more than 30%.

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Oct 7 • 6:02 AM EDT • Health • jsonline.com
See September business openings and what's coming to Abilene

Abilene saw business changes in September. See the month's openings and what's to come.

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Oct 7 • 5:45 AM EDT • Business • reporternews.com
'Medicare for All' message attracts midterm voters buckling under medical bills

Midterm candidates are talking up Medicare for All, and in a poll 2 out of 3 Americans said they support it. The phrase speaks to a desire for radical change, though many don't really know what it is.

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Oct 7 • 5:00 AM EDT • Health • npr.org
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Food Aid Enrollment Tanks After SNAP Rule Changes

It’s been more than a year since President Donald Trump signed the One Big Beautiful Bill Act, and SNAP enrollment is down more than 20% in Louisiana. Anti-hunger groups say far more people could lose access if states are required to cover more of the food program’s cost.

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Oct 7 • 5:00 AM EDT • Health • kffhealthnews.org
Communities worry for their health after Trump weakens pollution limits: 'It's a kick in the gut'

Biden-era changes to the Clean Air Act would have tightened regulations for industrial sites, but the Trump administration has given exemptions to hundreds of facilities. People living near the sites are concerned about air quality and their well-being.

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Oct 7 • 5:00 AM EDT • Health • kcur.org
Yankees news: Boone considering changes to the lineup

Boone eyeing lineup changes ahead of Game 3; Fried will start despite impending paternity; reasons to believe in a reverse sweep; McDowell passes at 84.

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Oct 7 • 5:00 AM EDT • Sports • sports.yahoo.com
The AI tune is changing: From a wave of hype to business realism

The AI revolution is not an overnight upheaval, but a calculated evolution. In the coming years, companies will not win simply because they adopted AI; they will win because they knew how to manage it optimally.

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Oct 7 • 4:13 AM EDT • Business • calcalistech.com
Planning Beyond 2030: What SAP Business Suite 7 and SAP NetWeaver Customers Using Third-Party Databases or Java Need to Know

Understand the coming changes and what they mean in practice.

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Oct 7 • 3:30 AM EDT • Business • news.sap.com
Congress Asset Management Co. Acquires New Holdings in Madison Square Garden Entertainment Corp. $MSGE

Congress Asset Management Co. bought a new stake in Madison Square Garden Entertainment Corp. (NYSE:MSGE - Free Report) during the third quarter, according to the company in its most recent Form 13F filing with the Securities & Exchange Commission. The fund bought 303,087 shares of the company's

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Oct 7 • 3:21 AM EDT • Entertainment • marketbeat.com
WHO endorses lifestyle changes over GLP-1 drugs in child obesity fight

The World ‌Health Organization on Wednesday recommended diet, exercise and counseling over popular weight-loss drugs in its first global guidelines addressing rising obesity among younger children.

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Oct 7 • 3:02 AM EDT • Health • reuters.com
Why ‘Wives’ is relevant to the times

Parvesh Cheena, actor in Jaclyn Backhaus’ play WIVES, at East West Players, co-produced with Hypokrit Live Arts. Photo by Daniel Antonio Vallejo. At a time when marginalized voices are changing the national conversation, Jaclyn Backhaus’ play Wives, featuring a South Asian American cast, is both relevant and funny. “This play offers its actors the opportunity to time travel, to play many…

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Oct 7 • 2:56 AM EDT • Entertainment • asianjournal.com
Scientists who put faith in technology less likely to take climate action

‘Techno-optimism’ may lead to reliance on unproven solutions at expense of societal changes needed

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Oct 7 • 2:00 AM EDT • Science • theguardian.com
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Eagles roster news: Tank Bigsby to IR, practice squad changes

Tweaks.

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Oct 7 • 12:46 AM EDT • Sports • sports.yahoo.com
Poll: Voters oppose redistricting ballot question when presented 'meat of the political outcome'

A proposed amendment to the Maryland Constitution that would change the way Maryland draws congressional districts faces stiff voter opposition, a new poll shows. It's the latest sign of trouble for the ballot question backed by Democratic leaders

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Oct 7 • 12:01 AM EDT • Politics • marylandmatters.org
Climate change and farming gave rise to ‘genetically distinct’ swan goose: study

New population of the migratory waterbird has emerged in the Chinese capital over the past century, according to researchers.

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Oct 7 • 12:00 AM EDT • Science • scmp.com
Nick Sirianni Finally Makes Real Admission About Struggling Eagles' Offense

Facing questions and average production, Philadelphia’s head coach knows something has to change.

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Oct 6 • 11:20 PM EDT • Sports • sports.yahoo.com
Jim Phillips: ACC does not have ‘unanimity’ on Protect College Sports Act

With the Protect College Sports Act heading to the House of Representatives, the ACC has become a key part of the conversation. Four school presidents from the conference penned a letter to House Speaker Mike Johnson (R-La.) requesting changes to the conference realignment provision last week. Speaking at ACC Tipoff on Tuesday, commissioner Jim Phillips […]

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Oct 6 • 9:40 PM EDT • Sports • sports.yahoo.com
CATIE | Canadian study links cardiovascular disease to declining brain health

As the population of people with HIV ages, researchers studied cognitive health changes; 46% of study participants were cognitively declining, with cardiovascular health playing a role.

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Oct 6 • 9:17 PM EDT • Health • eatg.org
U. Business School researchers find that girl dads are more attentive to their partners

Two Rutgers University researchers recently published a study that found having a daughter was associated with changes in fathers' psychology, including greater investment in the relationship he has with the child's mother.

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Oct 6 • 8:59 PM EDT • Business • dailytargum.com
ESPN's Stephen A. Smith Urges Bengals to Make a Change

Frustrated by a stagnant rushing attack and Joe Burrow’s mounting burden, Stephen A. Smith demands a coaching overhaul to rescue Cincinnati’s season before the star quarterback falters.

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Oct 6 • 8:10 PM EDT • Sports • sports.yahoo.com
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Californians are in a sour mood but don’t want to change the political status quo

All of the statewide offices, including the governorship, will remain in Democratic hands.

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Oct 6 • 6:44 PM EDT • Politics • ocregister.com
Bush-Wells Sporting Goods to close its doors at the end of the year

CASPER, Wyo. — After 63 years in business, Bush-Wells Sporting Goods will close at the end of this year. Changing business models in the industry,

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Oct 6 • 6:00 PM EDT • Business • oilcity.news
Is it time to end the Jacoby Brissett era?

Do the Arizona Cardinals need to make a change at quarterback?

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Oct 6 • 6:00 PM EDT • Sports • sports.yahoo.com
Three Senate races shift toward Democrats in Cook ratings

The latest changes reflect growing worries for Republicans.

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Oct 6 • 5:17 PM EDT • Politics • washingtonpost.com
Cartier Got Down to Business for the 20th Anniversary of the Women’s Initiative

Guests from across the arts, public health, philanthropy, and fashion gathered at the Morgan Library and Museum to celebrate the 20th anniversary of the Cartier Women’s Initiative: the maison’s fellowship for entrepreneurs focused on implementing social and environmental change.

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Oct 6 • 5:12 PM EDT • Business • vogue.com
Lane Johnson retires after changing the conversation around mental health

Lane Johnson’s decision to discuss his anxiety and depression publicly created an important legacy extending beyond his championships and individual honors

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Oct 6 • 4:53 PM EDT • Health • theeagleswire.usatoday.com
Dodgers NLDS Game 3 Lineup Changes: Ohtani Falls, Hernandez Debuts

Los Angeles Dodgers manager Dave Roberts shakes up the batting order for a pivotal Game 3.

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Oct 6 • 3:30 PM EDT • Sports • sports.yahoo.com
Commissioner touts ACC's health amid questions of departures

ACC boss Jim Phillips isn't fretting about Clemson, FSU, Miami and UNC wanting to tweak the Protect College Sports Act to make it easier for schools to change leagues.

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Oct 6 • 3:29 PM EDT • Health • abc11.com
Meet the GOP Boogeymen

A generational change in politics is here. Just ask Hasan Piker and Adam Mockler.

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Oct 6 • 2:59 PM EDT • Politics • slate.com
Commissioner touts ACC's health amid questions of departures

ACC boss Jim Phillips isn't fretting about Clemson, FSU, Miami and UNC wanting to tweak the Protect College Sports Act to make it easier for schools to change leagues.

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Oct 6 • 2:55 PM EDT • Health • espn.com
Commissioner touts ACC's health amid questions of departures

ACC boss Jim Phillips isn't fretting about Clemson, FSU, Miami and UNC wanting to tweak the Protect College Sports Act to make it easier for schools to change leagues.

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Oct 6 • 2:55 PM EDT • Sports • espn.com
ACC's Phillips touts league's health amid questions of possible departures, realignment in future

Atlantic Coast Conference Commissioner Jim Phillips says he isn't worried about four member schools supporting changes to the Protect College Sports Act

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Oct 6 • 2:42 PM EDT • Health • abcnews.com
US Supreme Court orders another look at how Washington state political maps are drawn

Monday’s action will not affect next month’s election. But it could lead to the state’s legislative district boundaries changing before they’re next scheduled to be redrawn in 2031.

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Oct 6 • 1:54 PM EDT • Politics • opb.org
iOS 27.2 beta 3: Here’s everything new

Apple released iOS 27.2 beta 3 to developers yesterday, and it includes a handful of changes and hints at future...

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Oct 6 • 1:52 PM EDT • Technology • 9to5mac.com
New Mexico Health Care Authority creates shareable resources about Medicaid changes

NEW MEXICO (KRQE) – The New Mexico Health Care Authority has launched a Medicaid Partner Toolkit to help community organizations, health care providers, advocates and other partners explain upcomin…

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Oct 6 • 1:20 PM EDT • Health • krqe.com
The Jets should change their running back approach

Over the last couple of years, one thing that has frustrated me with the Jets’ approach to offense has been their insistence on using Breece Hall as a do it all back. Hall is a very talented player, but I think it’s clear that he isn’t a complete back. He is an explosive play threat […]

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Oct 6 • 1:14 PM EDT • Sports • sports.yahoo.com
Midterm Election Update: Vaccines

Federal vaccine policy has shifted toward fewer recommended routine childhood vaccinations, more emphasis on individual decision-making, and greater skepticism about the safety and efficacy of some vaccines. The changes coincide with declining childhood vaccination rates, rising exemptions from school vaccine requirements, and a major measles resurgence.

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Oct 6 • 12:35 PM EDT • Health • kff.org
Moody’s changes Nationwide’s P&C business outlook to “positive”

Moody’s Ratings announced today that it has changed its outlook for Nationwide’s P&C business to “positive” from “stable.” The global ratings agency also affirmed its A1 rating for Nationwide’s financial services (NFS) business, and A2 rating for Nationwide Mutual Insurance Company and Nationwide’s P&C affiliates. “Moody’s p...

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Oct 6 • 12:34 PM EDT • Business • news.nationwide.com
Demand Change: Homer G. Phillips Sale Delay Endangers Vulnerable Seniors

Homer G. Phillips residents endure neglect, safety risks, and maintenance failures. Uncover the story behind Alderwoman Tyus's 'bullet in the head,' comment | 104.1 FM KMOX

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Oct 6 • 11:47 AM EDT • Politics • audacy.com
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Gears of War: E-Day - Surviving the First Night of Emergence

Today marks the worldwide launch of Gears of War: E-Day, now available on XBOX Series X|S, XBOX on PC, Game Pass and Steam. One of XBOX’s most iconic sagas returns to where it all began, taking players back to the opening hours of Emergence Day and the catastrophic event that changed the world of Sera […]

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Oct 6 • 11:00 AM EDT • Technology • news.xbox.com
‘A Mother’s Brain’ explores the neuroscience of motherhood

Neuroscientist Susana Carmona’s book guides readers through a new mom’s changing brain.

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Oct 6 • 11:00 AM EDT • Science • sciencenews.org
Old Dominion University Researchers Explore Connection Between Sinus Health and Voice Problems

A stuffy nose, facial pressure and a diminished sense of smell are familiar symptoms for people with chronic sinus problems. Changes to the voice may be less obvious. Researchers in Macon & Joan Brock Virginia Health Sciences at Old Dominion University are exploring a connection patients may not always recognize: the relationship between sinus conditions and voice problems.

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Oct 6 • 10:44 AM EDT • Health • odu.edu
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Brazil: Lessons from a Disaster

By Antonio Martins (Outras Palavras) Defeats become deeper and more prolonged when we misunderstand what caused them, avoid correcting course, and embrace “solutions” that only compound our mistakes. Lula’s government and the Brazilian left suffered a disaster in Sunday’s election. Contrary to every poll, the president finished the first round 2.2 million votes behind Flávio Bolsonaro—and, more significantly, 3.4 million votes below his total four years ago, when the machinery of the state was working against him and in favor of his opponent. His vote share declined in 98 percent of Brazil’s municipalities. The PL, the main party of the far right, elected 121 deputies and 28 senators, becoming the largest caucus in both houses of Congress. The parties aligned with the Centrão—Brazil’s bloc of transactional center-right parties—were somewhat diminished, but will still hold roughly 250 seats in the Chamber of Deputies and 35 in the Senate. That will make it easier to assemble the majorities needed to amend the Constitution or impeach Supreme Federal Court justices. If elected, Flávio Bolsonaro could appoint four members of the Court, substantially altering its internal balance of power. What produced these results? How can the far right be prevented from consolidating them into a prolonged political hegemony? And what is the essential change of direction the left now needs? Explaining the Disaster Across the commercial media and the exuberant chaos of digital platforms, interpretations are multiplying. Some focus on specific episodes: Lula’s absence from the Globo debate, his very close relationship with Alexandre de Moraes, or his emphasis on issues supposedly remote from most people’s everyday concerns, such as rare earth minerals. Among the more systemic interpretations, three seem especially questionable. One argues that the principal defeat was not the left’s, since its congressional representation declined only slightly. The decisive movement captured at the ballot box, according to this view, was a shift within the right itself—from the more moderate and transactional forces of the Centrão toward the more ideological and radicalized forces of the PL and Novo. A second interpretation holds that the nature of electoral and political processes has changed. The material interests and aspirations of society, it argues, no longer play the central role they once did; they have given way to forms of subjective self-identification that the left has yet to understand. And a third concludes that, because of these two developments, we should expect a political winter: a prolonged period in which the far right and the broader right dominate Brazilian political life. There are important elements in all three interpretations. The problem lies in what they deny or leave out: Lula’s third government was a small-bore government. It offered the majorities that elected it neither a clearly better life nor reasons to believe again in politics and its power to transform society. These failures flowed from two fatal accommodations, which I will examine below. As a result, the government suffered a slow but steady erosion of support. And, as has happened in so many Western countries, it gave the far right the opportunity to present itself as anti-system and to benefit from popular frustration and distress. The interpretation that emphasizes the migration of votes from the center-right and traditional right toward the far right has been advanced, among others, by the courageous journalist Leonardo Sakamoto. In his UOL column on Monday, October 5, he highlights the miserable behavior of the traditional conservative parties. Over the past four years, they repeatedly joined forces with the “neo”-fascists, helping to “normalize” them—a criticism that could equally be directed at almost the entire corporate media. Believing they could use the far right as a stepping stone, they instead ended up partly devoured by it. This was especially true in the Senate, where the PL’s gain of 13 senators and Novo’s gain of two came at the expense of the PSD, which lost nine; the MDB, which lost two; the PSDB, which lost two; and the PP, which lost one. Sakamoto’s observation is accurate and necessary, but it leaves uncomfortable questions unanswered. Why did the erosion of the Centrão benefit the far right rather than, for example, producing growth for the left—as has happened so many times before, both in Brazil and elsewhere? The answer is not difficult. Throughout its four years in office, Lula’s third government was almost invariably associated with the Centrão. Here lies its first accommodation: accepting the limits imposed by conservative institutions; avoiding, as much as possible, any attempt to strain those limits through popular pressure; and believing only in the modest changes that could be squeezed through openings in Congress. The failure of the campaign to end the six-day workweek is emblematic. Lula could have electrified the presidential race by pairing it with a popular campaign for passage of the measure. Instead, he chose to place his hopes in the hands of Senate president Rodrigo Alcolumbre. He generated no mass mobilization, did not force his opponents onto an uncomfortable defensive, and won no victory. In September 2025, the government squandered the greatest of its many opportunities to shake up conservative power in Congress. Popular opposition to the so-called Shielding Amendment—which, if approved, would have restricted criminal proceedings against members of Congress—brought crowds into the streets, mobilized primarily by artists and social movements. This opened the possibility for a broader political education: a campaign that could begin exposing the limits and dysfunctions of Brazil’s political system while putting Bolsonaro’s movement on the defensive for its predictable support of political privilege. The amendment was defeated. But the executive branch then backed away from the fight. It remained associated with an institutional world widely seen as corrupt, elitist, and indifferent to ordinary people’s struggles. In doing so, it forfeited its credibility as a vehicle for the protest vote. On Sunday, it reaped the bitter fruits. Are We Doomed? Taking a different approach from Sakamoto, the philosopher Moysés Pinto Neto and other writers have drawn attention, in their first analyses of October 4, to the fragmentation of the public sphere produced by Big Tech platforms. Through their algorithms, these platforms present each person with a different view of social reality. As a consequence, it becomes much harder to identify common material problems and demands—for example, the fight for labor rights or for a properly funded public health system. Voters no longer embrace such demands, these authors argue, because they no longer see themselves as part of a collective. Instead, they tend to value the identities assigned to them by neoliberal subjectivity—the role of the entrepreneur, for example. On this interpretation, the left’s possible error lies in clinging to outdated illusions. Moysés’s warning is highly relevant and resonates with arguments such as Naomi Klein and Astra Taylor’s “Apocalyptic Fascism and the Billionaires’ Bet.” Unlike a century ago, the far right no longer promises a radiant future. It concentrates instead on resentment—especially that of young men. “They belong to a generation that fears it may never own a home, but compensates with the pleasure it gets from constantly provoking progressives online. Convinced their future has been stolen, they share memes romanticizing historical authoritarian regimes,” the authors write. But Moysés seems to confuse this danger with inevitability. He fails to see that the left’s answer cannot be adaptation. On the contrary, it must strengthen the possibility of politics as collective action. Nor does he recognize that precisely such a reversal is already becoming possible in some of the most promising mobilizations of the twenty-first century: the election, at the end of 2025, of the young Muslim Zohran Mamdani as mayor of New York, on a platform centered on the intensely material fight for an affordable city; the Left Party’s victory in Berlin two weeks ago, built around the demand to expropriate private real-estate corporations; and the very recent wave of demonstrations in Spain—including an occupation of Madrid’s Puerta del Sol—in which tens of thousands of young people mobilized by the Tenants’ Union have demanded limits on rents. By putting itself in the straitjacket of the “fiscal framework” in the first months of 2022, Lula’s third government adopted the second fatal accommodation of its term. Faced with conservative institutions and a country devastated by four years of Bolsonaro, increased public investment was the government’s remaining weapon for offering a more dignified life to the majority and forging an anti-conservative pact with them. The same state that disburses 1 trillion reais a year to enrich a small class of rentiers could instead spend money to extend the Family Health Strategy to every Brazilian, at a cost of 30 billion reais; provide full-day public schooling and childcare to all adolescents and children—and, especially, relief to their mothers; achieve universal sanitation while cleaning up polluted urban rivers; multiply metro systems; begin transforming the urban peripheries; and undertake many other urgently needed projects. In April 2023, an article in Outras Palavras warned that the fiscal framework could “shrink the Lula government and preserve the forces that condemn the country to inequality and regression.” A year later, another article showed that restraints on public spending were strangling policies vital to ordinary people and undermining the president’s popularity. In November 2024 came a reality check, in the form of the government’s humiliating defeat in the municipal elections. Even then, the fiscal lock was neither removed nor loosened. On the contrary: throughout the government’s four years, fiscal restraint remained central to its political narrative. The administration proudly proclaimed that it had “put the state’s accounts in order,” without grasping either how misleading that phrase was—given the payment of 1 trillion reais in interest—or how badly the message was hurting it politically. Lula finally woke up in September 2026. The increase in Bolsa Família benefits, after four years of being frozen; the announcement that anti-obesity drugs would be offered through Brazil’s public health system; and the ban on online betting showed that the state has the power to act decisively on behalf of the majority when those in government are willing to confront obstacles. The huge marches that closed the campaign in Fortaleza, Salvador, Rio de Janeiro, and São Paulo on the eve of October 4 showed how such initiatives can mobilize activists and the broader public. But it was too late—and too little to change the outcome of the first round. History has not ended The possibility of a turnaround in the three weeks leading up to November 25 cannot be ruled out. It will not be simple or easy. Lula must not only make up a deficit of 2.2 million votes; he must also offset the movement of voters who backed other right-wing candidates in the first round, most of whom are likely to move toward Flávio Bolsonaro. Pulling that off will require a broad, grassroots effort to win over voters, potentially reinforced by new initiatives from Lula. The coming hours and days will be decisive. If Bolsonaro’s movement also wins the presidency, the result will create a high-risk situation for Brazilian sovereignty and democracy. The enormous challenges posed by such an outcome would require the left to reexamine, in depth and with a genuine willingness to engage in self-criticism, its political projects—or its lack of them—and its practices. But would that mean we are condemned to the long winter of far-right hegemony that some analyses are beginning to forecast? It is far too early to say, suggests a recent text by Álvaro García Linera, the thinker who served as vice president of Bolivia under Evo Morales. His central hypothesis is that this political current will prove short-lived. At a moment when the entire world is once again talking about sovereignty and protecting national economies, the far right offers a stale, recolonizing neoliberalism. Its submission to the United States is as blatant and pathetic as Flávio and Eduardo Bolsonaro’s overtures to Donald Trump. Its project amounts to something like every man for himself: greater inequality, capitalism without limits, devastation, and supremacism. Will it work? In the United States, just two years into his second term, Trump himself is reaching record levels of unpopularity and may be on the verge of losing Republican control of both the House and Senate in November. Every new beginning is difficult. Whatever the outcome of the second round, the defeats of October 4 show how profoundly the Brazilian left will have to rethink and rebuild. But just as it would be foolish to underestimate the seriousness of its mistakes, it would be equally foolish to conclude that rebuilding a political project is no longer possible. History has not ended. The times are moving faster than ever. Originally published in Portuguese by Outras Palavras. English translation by Eric Blanc; I’ve added the subtitles. More We can’t stop the far right at home or abroad without a revitalized labor movement, which is yet another reason why you should become a sustaining supporter of the Emergency Workplace Organizing Committee (EWOC) — one of US labor’s pivotal bright spots. Relatedly, Jacobin published a short piece of mine reflecting on a decade of Bernie Sanders inspiring a whole new generation of young worker organizers.

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Oct 6 • 10:08 AM EDT • Politics • laborpolitics.com
Red Wings Reverse Course in Simon Edvinsson Contract Talks

The Detroit Red Wings have changed course in Simon Edvinsson contract talks, with Elliotte Friedman reporting longer-term offers are now on the table.

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Oct 6 • 9:27 AM EDT • Sports • sports.yahoo.com
Paramount-Warners Mega Deal Closes Creating Skydance Hollywood Giant

The combined company, Skydance, will begin trading on the New York Stock Exchange this week.

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Oct 6 • 8:54 AM EDT • Business • hollywoodreporter.com
NAACP launches voter protection hub for midterm elections

The civil rights organization is stepping up efforts in response to President Donald Trump’s push to change voting rules.

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Oct 6 • 8:30 AM EDT • Politics • washingtonpost.com
AIAS+ 2026 Brings Leading Scientists to San Francisco to Explore How AI Is Changing Scientific Discovery

The Tianqiao and Chrissy Chen Institute will bring leading scientists, AI researchers, engineers and innovators to San Francisco November 5–7 for AIAS+ 2026: AI Advancing Science & Society, a three-day symposium focused on one of the most consequential questions facing research today: How can artificial intelligence help scientists move beyond analyzing what is already known and accelerate new discovery?

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Oct 6 • 8:00 AM EDT • Science • newswise.com
Lucy Smith: “The boundaries of the entertainment business are changing”

The Director of Mipcom Cannes and MIPJunior describes the highlights of next week’s market, which will explore the global transformation of the media business.

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Oct 6 • 8:00 AM EDT • Entertainment • senalnews.com
Sun Life research reveals the ripple effect behind small business success

As Canada's small businesses navigate a rapidly changing business environment, new research from Sun Life shows that success is about more than growing revenue. It's about building resilience. When owners feel confident in their ability to weather challenges and plan for the future, they're more likely to invest in their employees, strengthen their businesses and create lasting impact for the people who depend on them. The findings align closely with how Sun Life supports small business owners,

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Oct 6 • 8:00 AM EDT • Business • finance.yahoo.com
3 names emerging as possible replacements for Deion Sanders

Deion Sanders’ future at Colorado is facing renewed scrutiny after the Buffaloes fell to 2-3. If the school eventually makes a coaching change, Dan Mullen, Willie Fritz and Jason Eck could emerge as possible candidates, offering different combinations of Power Four experience, program-building success and recent momentum.

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Oct 6 • 7:30 AM EDT • Sports • sports.yahoo.com
CD Projekt Red outlines which Witcher 3 Remastered fixes are coming next, but there's still division about the changes

PS5 performance improvements are among the top priority issues CDPR is working on fixing for The Witcher 3 - Remastered edition.

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Oct 6 • 7:01 AM EDT • Technology • eurogamer.net
DC council to decide whether businesses can pay for extra parking enforcement
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Oct 6 • 6:21 AM EDT • Business • wjla.com
Trump wants to rewrite the midterm lexicon

Changing the words may not change the politics.

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Oct 6 • 6:20 AM EDT • Politics • axios.com
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List of DVD release dates for Oct. 6 and beyond

Following is a partial schedule of coming movies on DVD. Release dates are subject to change: OCTOBER 6: Moana 6: Jackass: Best and Last 6: Late Fame 6: Blades of

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Oct 6 • 5:45 AM EDT • Entertainment • recorderonline.com
NFL power rankings Week 5: No. 1 spot changes hands for third consecutive week
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Oct 6 • 5:11 AM EDT • Sports • sports.yahoo.com
AI is changing entertainment. Here's what investors are betting on

New Delhi, Oct. 6 -- Recent investments in media and entertainment, from Prime Focus-backed Brahma AI raising $150 million to AI-native live entertainment discovery and ticketing platform thumpN raising over $3.75 million, might suggest that artificial intelligence has become the industry's newest…

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Oct 6 • 5:04 AM EDT • Entertainment • tradingview.com
'A Statement' review: Star-studded climate change drama is more than just hot air

Paul Rudd, Paul Giamatti, and more lead a star-studded climate change drama.

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Oct 6 • 5:00 AM EDT • Entertainment • mashable.com
Current and Historical Public Opinion on Medicare-for-All and Other National Health Plan Proposals

This chart pack summarizes KFF polling data on public opinion on Medicare-for-all and other national health plan proposals. The latest update finds that two-thirds of the public supports Medicare-for-all, while support changes drastically as respondents hear arguments from proponents and critics.

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Oct 6 • 5:00 AM EDT • Health • kff.org
Eagles Run Game Continues to Be An Issue, and There Are Many Reasons Why

Something has to change.

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Oct 5 • 10:35 PM EDT • Sports • sports.yahoo.com
Countries race to provide oral health care for all in 100-Day Sprint across Asia

Twenty Asian countries and areas across the WHO Western Pacific and South-East Asia regions vowed to strengthen essential oral health benefits as part of a “100-Day Sprint” initiative, during the 16th Asian Chief Dental Officers Meeting held from 27 to 29 September in Kota Kinabalu, Malaysia. The meeting marked the midpoint of the 100-day sprint bolstering support for countries to develop essential oral health benefit packages that can be integrated into national universal health coverage plans. Convened by the two WHO regional offices and the Malaysian Ministry of Health as the Secretariat, the meeting brought together national oral health leaders from 20 Asian countries, staff from all levels of WHO, WHO collaborating centres and other development partners. Participating countries and areas included: Bangladesh, Bhutan, Brunei Darussalam, Cambodia, China, Hong Kong (SAR) China, India, Indonesia, Japan, Lao People’s Democratic Republic, Malaysia, Maldives, Mongolia, Nepal, the Philippines, Singapore, Sri Lanka, Thailand, Timor-Leste and Viet Nam. Participants reviewed progress and refined proposals using the WHO Service Package Delivery and Implementation (SPDI) Platform. Countries conducted bottleneck analyses across four key areas: service delivery, workforce, access to essential medicines and health products, and health financing. They identified practical actions to address implementation challenges and refined proposed revisions to their national oral health benefit packages. “There is no health without oral health. Through the 100-Day Sprint, countries are advancing the implementation of the Western Pacific regional implementation plan on oral health and strengthening progress towards universal health coverage,” noted WHO Regional Director for the Western Pacific Dr Saia Ma'u Piukala. Participants identified bottlenecks and proposed workable solutions to strengthen access to essential oral health care through primary health care, sharing experiences and discussing how best to translate policy commitments into feasible and sustainable action at the country level. Malaysian Minister of Health Datuk Seri Dr Dzulkefly Ahmad highlighted the importance of prevention and primary health-care approaches to improve oral health: “Oral diseases can have lifelong consequences, yet many are preventable. By integrating essential oral health care into primary health care and promoting prevention in schools and communities, we can improve oral health across the life course.”The WHO team led by Dr Huong Tran, Director of the Division of Health Promotion, Disease Prevention and Control of the WHO Western Pacific Region and national oral health leads from over 20 Asian countries visited the SK Pekan Putatan School, Sabah for school oral health programme including flouride mouth rinsing. © WHO / V. ChaudharyDr Huong Tran, Director of the Division of Health Promotion, Disease Prevention and Control for the WHO Western Pacific Region, emphasized key collaborative roles WHO can play. “Oral diseases are the most common noncommunicable diseases, yet many can be prevented and treated through essential oral health services delivered at the primary health-care level,” she said. “By sharing experiences and using WHO tools such as the SPDI Platform, countries are accelerating progress towards universal health coverage for oral health.” “Integrating oral health into broader health services is essential for reducing inequities, expanding access and recognizing oral health as an integral component of overall health and well-being. The 100-Day Sprint provides an important opportunity to translate this commitment into practical action and ensure that quality oral health services reach all people, especially those most in need,” said Dr Suman Rijal, Director of the WHO South-East Asia regional Department of Healthier Populations and Noncommunicable Diseases. As host of the meeting, Malaysia showcased ongoing efforts to strengthen oral health care through primary health care and prevention-focused approaches, while providing a platform for countries across the two WHO regions to exchange experiences and accelerate progress towards universal health coverage for oral health. “WHO is encouraged by Malaysia's leadership in addressing the burden of oral diseases and advancing universal health coverage for oral health through practical, country-led action,” said Dr Rabi Abeyasinghe, WHO Representative to Malaysia, Brunei Darussalam and Singapore. Countries will continue to refine and figure costs for national oral health benefits during the remaining sessions of the 100 days. These efforts support implementation of the WHO Global strategy and action plan on oral health 2023–2030, while also helping to expand access to essential oral health services through stronger and more equitable health systems across the WHO Western Pacific and South-East Asia regions.______________For more information, or to arrange media interviews, contact: WHO Regional Office for the Western Pacific: wprocom@who.int WHO Regional Office for South-East Asia: SEMediaRelations@who.int

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Oct 5 • 8:00 PM EDT • Health • who.int
Scientists finally see how nature moves energy so efficiently

Researchers have captured key steps in a chemical reaction that helps nature transfer energy with remarkable efficiency. Ultrafast X-rays revealed how changes involving electrons and protons are closely linked to the rearrangement of surrounding water molecules. Because similar reactions drive photosynthesis and other energy-conversion processes, the technique could help scientists develop better catalysts, fuel cells, and flow batteries.

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Oct 5 • 8:00 PM EDT • Science • sciencedaily.com
Solana Beach market owners say immigration enforcement is hurting business

A family-owned business in Solana Beach says immigration enforcement operations in the area are hurting sales. Now, the owners fear the market's future may be at risk. NBC 7's Ignacio Dominguez shows us how the North County neighborhood is changing.

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Oct 5 • 7:51 PM EDT • Business • nbcsandiego.com
UCLA Health awarded $4M NIH grant to study why ulcerative colitis symptoms persist after inflammation subsides

UCLA Health gastroenterologist Lin Chang and Dr. Bruce Sands of Mount Sinai were awarded a $4 million federal grant to investigate why some ulcerative colitis patients continue to experience irritable bowel syndrome-like symptoms even after inflammation has subsided.

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Oct 5 • 7:50 PM EDT • Health • newswise.com
Teen Corner: Minnesota’s new K-12 health standards

For the first time, Minnesota has statewide K-12 health education standards, covering everything from mental health and nutrition to sexual health and substance use. In another Teen Corner, pediatrician Dr. Maddie Gagnon from Gillette Children’s and founder of Pulse Parenting joins us to break down what’s changing and what it could mean for kids and parents.

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Oct 5 • 4:51 PM EDT • Health • fox9.com
Teaching students scientific-storytelling skills to inspire change

The senior capstone course ESCI 191 equips environmental-science majors with digital-storytelling skills to translate complex climate data into compelling narratives to immerse and engage the public.

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Oct 5 • 4:37 PM EDT • Science • news.ucsc.edu
Why I Don’t Think Ride Or Die Should Have Been Cancelled (And What Company Should Save It...)

(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) So…I recently came across a Reddit thread, talking about films on streaming, wondering why there are no reliable sources out there for streaming ratings data. Sigh. Honestly, as annoyed as I am that so many still don’t realize that we have streaming ratings, I somewhat get it. Until now, there was such a long delay between when a show or film came to streaming and when we got its viewership data; I understand why people were confused. (But, as you know, this just changed.) Also, even back in the day, how many people knew how well films did on television? Luckily, as a reader, you’re in the know. Okay, on to this week’s issue. I want to take a look at Prime Video cancelling Ride or Die and whether I agree with that decision. Overall, we didn’t have any breakout hits (no TV shows landed over 20 million hours according to Nielsen) but we have a lot of steady performers on the streaming charts. Plus, we’ll look at where $50 million in missing box office dollars went. (Spoiler: straight-to-streaming.) All that, plus new episodes of The Secret Lives of Mormon Wives, Supergirl heads to streaming, a new YA show does well on Netflix, the viewership for the Daily Wire’s $50 million fantasy show, what TV show hit-maker can’t make streaming hits, CD sales, all the flops, bombs and misses, and a whole lot more. Let’s dive right in! (Reminder: The streaming ratings report focuses on the U.S. market and compiles data from Nielsen’s weekly top ten viewership ranks, Luminate’s Top Ten Data, JustWatch and Reelgood interest data, Samba TV household viewership, company datecdotes, Netflix hours viewed data, Google Trends, and IMDb to determine the most popular content. While most data points are current, Nielsen’s data covers the weeks of September 7th to September 13th, 2026. You can find a link to my terminology here.) Subscribe Television - Ride or Die Is a Hit…But It Got Cancelled? What The Data “Says” I hate the phrase “here’s what the data says”, even though sometimes I find myself using it. If data just told us everything, we data folks would be out of a job! Data is often messy, complicated and nuanced. When it comes to strategy, many of the best decisions can’t actually use “data”, since it’s vastly too complicated to model. Anyways, I’ve been singing the praises of Prime Video’s Ride Or Die this summer, a show that did very well for them. And yet…it got cancelled. Now, usually when a show gets cancelled, a bunch of websites say “a hit show got cancelled”... Here’s the thing, though: in this case, they’re right! The data “says” that this show was a hit. Specifically, out of 522 first seasons to make a week on the Nielsen charts since 2020, it’s the 75th biggest. On Amazon, Ride or Die is eighth out of 41 first seasons: That’s top 15th percentile all time, almost exactly, which is my definition of a “hit”! I mean, outside of Reacher, Amazon needed a hit this summer! (Admittedly, Off Campus did well for Amazon in the spring, but Ride or Die performed even better.) So what happened? Why did Amazon cancel one of their rare 2026 bright spots? Well, Deadline reported a reason—which I’ll get to—but I’d break it down into three relevant questions: What is a given streamer’s reasoning? Is that reasoning sound? Could the stated reason not be the real reason? According to Deadline, Amazon felt the show “over-indexed” in middle-aged women. (This was based on leaks from within Amazon.) The logic is this: Amazon already reaches this demographic because of unlimited two-day shipping bundled with Prime, so they don’t really need more shows like this. Now, it’s my job to ask if that’s a good reason, and I’ll be honest, in this case, I don’t think it is. Sure, this show may “over-index” in middle-aged women—I’ll just assume that’s the case here—but I think folks often oversell how important over-indexing actually is. When a show is a “hit”, it isn’t a bit bigger than its rivals; it’s usually multiples bigger. For example, Elle only made the charts for two weeks at 8.3 million hours each. So Ride or Die was 80% bigger in its first two weeks, and likely had a much stronger hold, with its terrific 13 million hours in week three. Ride or Die was nearly three times bigger than Sterling Point through three weeks too. And that means that _Elle, Sterling Point a_nd other Amazon YA shows need to not just over-index a little with younger women (assuming that’s who Amazon prefers over middle-aged women), but massively over-index. Otherwise, more people in that demo (and a bunch more besides) likely watched Ride or Die. (I’ll try to explore this concept more in a future article.) And don’t get me started on how Ride or Die did compared to a certain (very, very popular, possibly the world’s most popular) YouTuber’s reality show…which didn’t make the charts after its first week and likely cost much, much more than Ride or Die. All to say, Amazon-MGM Studios/Prime Video can tell reporters that this show didn’t reach the right audience, but that excuse feels weak to me. So this leads to the third question: could other reasons have come into play? Yes! Renewal or cancellation decisions rarely (I’m tempted to say “never”) boil down to one variable. At its simplest, it’s two things: budget versus viewership. But often factors like critical acclaim, ownership and, yes, personal opinion come into play. In this case, Amazon has a new executive running things, and this show isn’t owned by Amazon-MGM Studios (unlike Elle). And yes, it may not have indexed with the right target viewers, too. Likely all of those factors came into play.1 My guess is ownership ended up mattering most. Amazon doesn’t own Ride or Die. It’s actually produced by another major studio. Fortunately/allegedly, this show is being shopped around. I can think of one brand new CEO who should consider it for one of his two major streamers…especially if he wants to rebuild goodwill in Hollywood. His name is on this list of exec producers of Ride or Die… If David Ellison needs some goodwill—and he does—rescue this female-led show tomorrow and grab some good headlines for a day. The data justifies it. Quick Notes on TV We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… How The Secret Lives of Mormon Wives latest season did on Hulu, post-controversy... Whether Supergirl soared on HBO Max... Why the box office is losing money due to the streamers... The viewership for the Daily Wire’s $50 million fantasy show... Updates on The Gentlemen, Lanterns, Outer Banks, King of the Hill and more... What former hit-maker has three streaming flops in a row... Whether The Mandalorian and Grogu popped in week two... All the flops, bombs and misses... And a whole lot more... ...please subscribe! We can only keep doing this great work with your support. If you want an idea of just how much content you’d get in a full issue, check out this older issue. Coming Soon! Oh man, we’re almost caught up! We just have two more issues, then the streaming Ratings Report will be coming out just two weeks after a TV show premieres! Next issue, I’ll be looking at the first two weeks of the NFL Thursday night games on streaming, a huge new spinoff, Reacher’s Neagly on Prime Video, and the latest edition of Monster: The Lizzie Borden Story on Netflix, the return of Slow Horses on Apple and MobLand (quietly one of their biggest shows) on Paramount+, and Dancing with the Stars on both ABC and Disney+. Plus I’ll take a look at animation for adults in 2026. The week after, a ton of movies are coming to streaming: Toy Story 5 on Disney+, Backrooms on HBO Max, Jackass: Best and Last on Paramount+ and The Breadwinner on Netflix, plus a Unabomber film on Netflix and a romcom on Prime Video. Woody Harrelson and Matthew McConaughey have a show on Apple, along with a game show inspired by Willy Wonka that everyone seems to hate. Long term, some crazy (but hopefully crazy like a fox) IP news. FX ordered a new Sons of Anarchy show from Charlie Hunnam, but it’s not about the biker gang. No, it features the show’s cast playing themselves in a new “meta-thriller”. Huh. And a lot of the cast is coming back. Next, Ryan Gosling is producing a Flintstones movie about a “grown-up Bamm-Bamm Rubble”. Also, huh. This one is in “early development” so we’ll see what happens. Both projects are based on IP, but also seem to have crazy takes on the IP, which I like.

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Oct 5 • 3:42 PM EDT • Entertainment • entertainment.substack.com
Deep dive
😐 Neutral (15%)
wow
63%
ahah
37%
180-employee Manatee HVAC, plumbing company names new CEO

Arctic Air Home Services makes a leadership change as it aims toward growth in the region.

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Oct 5 • 2:22 PM EDT • Business • businessobserverfl.com
Rural and Urban Health Center Patients and Financing

This brief reports on rural and urban health center patients and financing in 2025 using national data from the Uniform Data System (UDS) and examines potential impacts of recent federal policy changes.

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Oct 5 • 1:47 PM EDT • Health • kff.org
Planet Fitness acquires Bakersfield’s Body Xchange Health Club locations

Body Xchange Health Clubs announced that they have been acquired by Planet Fitness.The announcement was posted on their social media pages.The company said that

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Oct 5 • 1:40 PM EDT • Health • bakersfieldnow.com
Amy Coney Barrett calls oil companies’ arguments ‘slippery’

Supreme Court Justice Amy Coney Barrett criticized fossil fuel companies as “a little slippery” in oral arguments over a lawsuit in which oil majors claim that federal law blocks states from suing them for climate change-related damages. Her comment came in arguments Monday in the case Suncor Energy v. County Commissioners of Boulder County, which […]

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Oct 5 • 1:35 PM EDT • Politics • coloradopolitics.com
Deep dive
😐 Neutral (9%)
ahah
56%
wow
44%
Supreme Court kicks off new term with major climate case

The Supreme Court returns for its new term on Monday, and oral arguments in a major case over the fate of a costly climate change lawsuit brought by Boulder County, Colorado, will kick off a term set to feature several blockbuster legal battles. Suncor Energy v. County Commissioners of Boulder County will decide whether a […]

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Oct 5 • 1:26 PM EDT • Politics • coloradopolitics.com
Supreme Court sounds wary of state-based climate change suits against oil producers

Oil and gas producers hope the Supreme Court will shut down scores of lawsuits over the impact of climate change.

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Oct 5 • 1:23 PM EDT • Politics • latimes.com
Apple notifies Apple Cash users about two upcoming changes

Apple Cash’s terms and conditions have just been updated, and Apple is notifying users about two upcoming changes in particular.

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Oct 5 • 1:14 PM EDT • Technology • 9to5mac.com
Congressional candidates discuss expanding executive power and need for political will

Congressional approval ratings are in the tank. By some measures this is one of the least productive sessions of Congress in living memory. WGLT's Charlie Schlenker reports those things may not change much any time soon.

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Oct 5 • 1:00 PM EDT • Politics • wglt.org
God Packs are Officially Coming to Magic: The Gathering

Magic: The Gathering booster packs have gone through a lot of changes in the last decade, some of which have been awful. But Wizards of the Coast are introducing 'God Packs' to MTG, which could feel like winning the lottery.

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Oct 5 • 12:35 PM EDT • Technology • ign.com
US commodities regulator proposes new federal crypto oversight rules

The U.S. Commodity Futures Trading Commission proposes new federal rules for crypto exchanges offering leveraged trading to streamline regulation.

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Oct 5 • 12:25 PM EDT • Business • virginiabusiness.com
Richie Floyd: Bernie’s 2016 Campaign Changed My Life

In 2021, Richie Floyd was elected to the St Petersburg City Council, becoming the first openly socialist elected official in Florida in over a century. Writing in Jacobin, Floyd explains how Bernie’s ...

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Oct 5 • 12:18 PM EDT • Politics • yahoo.com
Who will rural voters blame for harmful healthcare changes, policies this election?

Inflation and affordability, immigration and international conflicts may be dominating much of the news—and voters' attention—but healthcare, as always, still matters at the ballot box—perhaps even more so for rural voters.

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Oct 5 • 9:43 AM EDT • Health • news.umich.edu
ESPN predicts Auburn's remaining schedule after SEC loss to Tennessee

How did Auburn football's 2026 outlook change following its Week 5 loss to Tennessee?

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Oct 5 • 9:09 AM EDT • Sports • sports.yahoo.com
'Chicago Fire' Season 15 cast – Who's back, exiting amid premiere

Prepare to see some changes when "Chicago Fire" returns this week. The NBC series will see multiple exits amid its 15th season, set to premiere Oct. 7.

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Oct 5 • 8:26 AM EDT • Entertainment • centraloregondaily.com
You should care about politics

Ever since America’s founding, the United States has been extremely politically charged. From the civil war in the 1860s, to the civil rights movements of the 1950s, America has always had politics at the root of economic, social and institutional change. So then why do Americans care so little about it? In 2024, about 63.9...

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Oct 5 • 8:00 AM EDT • Politics • thesandb.com
Scientists reveal what seven days of fasting does to the human body

Scientists found that prolonged fasting triggers major changes throughout the body, but many of the most interesting effects only appeared after about three days without food. The results suggest fasting may influence health in ways that go beyond weight loss and could eventually inspire treatments that mimic its effects.

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Oct 5 • 8:00 AM EDT • Science • sciencedaily.com
October 2026: Open Enrollment Starts Today

The 2027 insurance open enrollment is October 5-30, 2026. Changes made during this period will take effect January 1, 2027.

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Oct 5 • 8:00 AM EDT • Health • etf.wi.gov
Democrats want to change the rules for recall elections. Voters get their say with Prop. 5

Democrats say the recall process has gotten out of hand and they want to drop the 'second question' to replace a politician.

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Oct 5 • 8:00 AM EDT • Politics • calmatters.org
Success Supper Club

Drew native Stafford Shurden is bringing entrepreneurs together to exchange ideas America was built on the backbone of entrepreneurs. Through the centuries, visionary men and women in this country saw opportunities not only to develop and grow a business, but also to forge a path to encourage and inspire others. Drew native, Stafford Shurden […]

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Oct 5 • 7:51 AM EDT • Business • deltabusinessjournal.com
As Twin Cities suburbs grow more diverse, some old political patterns persist

City councils tend to be whiter than the places they represent. Some politicians and advocacy groups want that to change.

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Oct 5 • 7:00 AM EDT • Politics • startribune.com
$350 million Memorial Health project to bring road and parking changes

A $350 million Memorial Health project will add a 90-bed tower, cafeteria, loading dock and parking garage.

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Oct 5 • 6:50 AM EDT • Health • wjcl.com
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth

Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine

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Oct 5 • 6:44 AM EDT • Science • goldrushcam.com
Is a ‘political’ email sent with county government resources worth a $5K fine?

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An 8-justice Supreme Court to decide whether cities can sue oil companies for climate change impacts

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Oct 5 • 5:00 AM EDT • Politics • cnn.com
Rules analyst reveals game-changing referee mistake

Earlier this season, the Michigan Wolverines benefited from a controversial replay decision that put one more second on the clock, allowing for one last heave at the end zone, only for governing bodies to later conclude that protocol was not correctly followed. A similar situation happened this week at the FCS level. During Friday night’s…

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Oct 5 • 1:39 AM EDT • Sports • sports.yahoo.com
Sisters in Birth launches vocational school to improve Mississippi’s maternal health numbers

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How Extending CVS Distribution Through 2032 At Cardinal Health (CAH) Has Changed Its Investment Story

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Oct 5 • 12:25 AM EDT • Health • finance.yahoo.com