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Notre Dame men join women in winning inaugural three-weapon title
Notre Dame's Ahmed Hesham won the men's saber Sunday, and the Fighting Irish men joined the women in winning the inaugural three-weapon national championship at the Joyce Center.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Sebastian Kehl exits role as Borussia Dortmund sporting director
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Acuff scores 36 as Arkansas holds off No. 12 seed High Point 94-88
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Curzan lifts Virginia women to sixth straight NCAA swim title
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Mainieri out as South Carolina's baseball coach in 2nd season
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Wisconsin's Caroline Harvey wins Kazmaier Award as top player
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One All-in-One AI Platform, Endless Business Possibilities for Just $85
1min.AI combines writing, images, and video.
Alabama's Tyler Fay pitches no-hitter against Florida
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Cori Close hails Lauren Betts's 'courageous vulnerability' on mental health
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How to watch 2026 NCAA swimming and diving championships
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Tilman Fertitta Bid Puts Caesars Entertainment Value And Future In Focus
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Unilever in talks to combine food business with McCormick, WSJ reports
Unilever is in talks to separate its food business and combine it with spice maker McCormick in an all-stock deal which could come within weeks, the Wall Street Journal reported on Thursday, citing sources.
Unilever in Talks to Combine Food Business With McCormick, Report Says
Unilever Plc, the maker of Hellmann’s mayonnaise, is in talks to combine its food business with McCormick & Co., according to a report in the Wall Street Journal citing people familiar with the matter.
Exclusive | Unilever in Talks to Separate Food Business and Combine It With McCormick
The remaining Unilever company would focus on beauty, personal-care products and home.
Xiaomi releases new lightweight laptop with Intel Panther Lake and 120 Hz OLED display
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MLB reaches agreements with Polymarket, federal commission
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3M to create a leading fire and safety business; acquires Madison Fire & Rescue and combines with Scott Safety
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This heart-healthy diet may also lower the risk of dementia
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Tanvi, Ayush, Anmol in action at Orleans Masters; SC Delhi face Jamshedpur in ISL: Indian Sports LIVE, March 19
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2026 NCAA women's Frozen Four ice hockey: How to watch on ESPN
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Bangladesh sports minister to consult ICC on future of BCB
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Srikanth, Ayush in action at Orleans Masters: Indian Sports LIVE, March 18
Here are all the updates from Indian sports on March 18, 2026.
Minnesota fires women's hockey coach Frost after 19 seasons
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Champions League live updates: Arsenal-Leverkusen, Man City-Real Madrid
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Allina Health, California-based Sutter Health announce intent to combine companies
Allina Health to Join Sutter Health, Creating Bold Vision for Nonprofit Healthcare
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Sutter Health to combine with Midwest provider Allina
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Sutter Health looks to combine with Minnesota hospital system
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Microsoft combines Copilot teams and moves Mustafa Suleyman to focus on frontier AI models
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Hawks fans sport Magic City gear despite canceled promotion
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Prannoy, Srikanth among Indians at Orleans Masters; Rajasthan United face Real Kashmir in IFL: Indian Sports LIVE, March 17
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Oregon QB Dante Moore reveals struggles with mental health
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FC Goa face Punjab FC in ISL: Indian Sports LIVE, March 16
Here are all the updates from Indian sports on March 16, 2026.
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U.S. completes historic hockey sweep in Olympics, Paralympics
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Sources: Atlantic 10 set to hire Dan Leibovitz as commissioner
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Arkansas men, Georgia women take home titles at NCAA indoors
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NorthEast United host Jamshedpur, Inter Kashi face Mumbai City in ISL: Indian Sports LIVE, March 15
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West Virginia repeats, wins program's 21st NCAA rifle title
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NCAA wrestling championship: All-time winners list
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Pittsburgh businesses ready for 2026 NFL Draft
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Satwik-Chirag in Swiss Open quarters, India vs Italy in FIH WCQ, IFL continues: Indian Sports LIVE March 13
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Empathy is complicated in a results-based business like NASCAR
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The World’s Richest Sports Team Owners 2026
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Satwik-Chirag in Swiss Open second round: Indian Sports LIVE, March 12
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Big Ten asks NCAA to pause tampering inquiries, revamp rules
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Quinn Cook says overseas hoops career hurt by global politics
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Qunn Cook says overseas hoops career hurt by global politics
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CERN Science Gateway celebrates its 1000th science show
CERN Science Gateway has reached another milestone: the delivery of its 1000th science show! Since opening its doors in October 2023, Science Gateway has welcomed nearly 900 000 visitors of all ages to explore the fundamental questions of the Universe. Among its most popular activities are the science shows – dynamic, interactive demonstrations led by CERN guides and tailored to a broad audience of different age levels, including school groups, families and the general public. Designed to make complex scientific concepts accessible and entertaining, these live shows combine spectacular experiments, multimedia elements and audience participation. From the physics of particle collisions to the properties of superconductivity, electromagnetism and cryogenics, the science shows translate the research carried out at CERN into engaging visual experiences. Visitors might see superconductors levitate, follow particles through different detector layers or discover the beauty in phase transitions. Each demonstration is carefully crafted to spark curiosity while maintaining scientific accuracy. Members of the CERN community are of course warmly invited to visit CERN Science Gateway with their family or friends and attend one of the science shows. To register, please visit this page, and don’t forget to check the programme for the coming days. Become a CERN guide and run your own super-cool science show (and more)! To become a CERN guide, you can join the introduction course held every 3–4 weeks, which will give you an overview of what being a CERN guide entails. From there, further courses are available depending on what type of guide you would like to be. Because, of course, CERN guides are needed everywhere at CERN. If you imagine yourself as a more ‘traditional’ guide, you should know that there are currently more than ten exciting visit points in CERN’s visits portfolio, such as the Antimatter Factory, the ALICE experiment (surface), the Alpha Magnetic Spectrometer (AMS) control room, the ATLAS experiment (surface), the CERN Control Centre (CCC), the Data Centre, the LHCb experiment (surface), the Synchrocyclotron (SC), the SM18 test facility and the newly inaugurated Linac2 visit point. Indeed, CERN’s Visits Service and Visual Impact and Exhibitions Section recently collaborated on redesigning the Linac2 visit tour, which has just reopened to the public after several months of renovation work. The new tour offers visitors and guides alike an enriched, more immersive experience, designed to highlight the history and scientific significance of this major facility. So, fancy becoming one of the insiders? Join the introduction course, check the guides website or contact guides.manager@cern.ch. And remember, becoming a guide can benefit you, too.
India face Wales in women's hockey World Cup qualifiers: Indian Sports LIVE, March 11
Here are all the updates from Indian sports on March 11, 2026.
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Marshall sued over plans to drop women's swimming and diving
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Bills’ 2026 NFL Mock Draft roundup after NFL Combine
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India face Chinese Taipei in women's Asian Cup: Indian Sports LIVE, March 10
Here are all the updates from Indian sports on March 10, 2026.
Sabres, Lightning battle in one of the wildest NHL games in decades
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Patriots’ 2026 NFL Mock Draft roundup after NFL Combine
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Rutgers beats Penn State 74-62 to sweep season series
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Porzingis, back from illness, says he 'will be healthy now'
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Bears’ 2026 NFL Mock Draft roundup after NFL Combine
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Bengals’ 2026 NFL Mock Draft roundup after NFL Combine
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MSU computer science professor teaches use of AI combined with human knowledge
MSU computer science professor teaches use of AI combined with human knowledge
Trump plans executive order to address college sports issues
President Donald Trump on Friday said he would write an executive order within a week that would "solve all of the problems" brought forth in an unprecedented meeting at the White House to address the future of college sports.
Combat star Francis Ngannou released by PFL, now a free agent
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Kristi Noem was a font of inspiration for comedy and memes. What now?
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Bengals Post-Combine, Pre-Free Agency 3-Round Mock Draft
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UFC champ Aspinall inks business deal with boxing promoter Hearn
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3L Kevin Afiesh Learns to Translate Legal Risk Into Business Strategy as FinTech Extern - UC Law San Francisco (Formerly UC Hastings)
3L Kevin Afiesh strengthened his corporate and fintech skillset through an externship at Plaid, gaining real-world experience at the intersection of technology and financial services. 3L student Kevin Afiesh shares how UC Law San Francisco’s Corporate Counsel Externship provided immersive, practice-ready training inside Plaid’s in-house legal department. Reviewed and analyzed technology-focused agreements, including emerging AI provisions and liability terms Explored financial services regulation and data governance within a growth-stage company Learned how internal legal teams shape product, partnership, and compliance planning 3L student Kevin Afiesh: During my externship at Plaid, I worked with the in-house legal team supporting a rapidly growing company at the intersection of technology and financial services. My work focused primarily on corporate, commercial, and intellectual property matters. I helped review and analyze vendor and partnership agreements, paying close attention to emerging artificial intelligence-related provisions and risk allocation terms. I also investigated regulatory and compliance issues involving financial services and data governance, and I researched intellectual property litigation relevant to fintech companies. This work supported legal risk assessment to guide strategic decision making. I learned firsthand how an in-house legal team operates in a highly regulated, innovation-driven environment, where legal analysis is closely integrated with business decision making. I saw how attorneys balance legal risk with commercial priorities and how their advice shapes contracting, compliance, and intellectual property strategy. It reinforced that effective in-house lawyers need to understand both the law and the operational realities of the business. The experience also strengthened my ability to communicate complex legal concepts clearly to non-lawyers and to provide advice that is precise, practical, and commercially aware. Throughout my academic and professional journey, I’ve worked with technology companies at different stages. Plaid added a distinct perspective within the tech ecosystem, showing me how a growth-stage fintech company approaches regulatory complexity, innovation, and risk tolerance. This sharpened my ability to adapt to clients with different structures, priorities, and compliance needs. As I prepare to practice corporate law in the technology industry, this exposure has strengthened my ability to align legal advice with a company’s stage of growth, strategic objectives, and internal dynamics. I would absolutely recommend the Corporate Counsel Externship Program. Working directly with an in-house legal team provided a meaningful sense of day-to-day practice inside a technology company, and the attorneys at Plaid were generous with their time and mentorship. The classroom component was equally valuable. Professors Nira Geevargis and Scott Darling created a thoughtful environment where we reflected on our experiences, discussed real-world challenges, and developed practical skills that complemented our fieldwork. More broadly, UC Law San Francisco’s location offers a clear advantage for students interested in technology, corporate practice, and public-interest work. Proximity to courts, law firms, and innovative companies — combined with programs like the Corporate Counsel Externship and an extensive Bay Area alumni network — make it a strong option for students who want to build their careers in the region. The Evidence of Success series highlights UC Law SF students as they share how the college’s opportunities equip them with the experience, skills, and confidence to excel in the legal profession.
Disney Bull vs Bear: What Big Changes at the Entertainment Giant Really Mean for Investors
Walt Disney (NYSE: DIS) is at an inflection point. With Bob Iger stepping aside and parks chief Josh D’Amaro set to take the helm, combined with a $9.25 billion credit facility secured on March 3, 2026, investors face a genuine fork in the road. Here is what each side of the argument looks like for ... Disney Bull vs Bear: What Big Changes at the Entertainment Giant Really Mean for Investors
Beyond the Valley – Entertainment: Riverboats schedule 2026 stops in Marietta
MARIETTA — A schedule has been announced for two passenger river cruise ships that will be in Marietta this summer. The American Melody and the American Heritage will make a combined 14 stops in Marietta between July 1 and Aug. 24 at the levee on the Ohio River, the Marietta-Washington County Convention and Visitors Bureau […]
2026 NFL mock draft 6.0: Chiefs stick with offense after big trade with Rams; Ohio State defenders rise after stellar combines
Scientists build a “periodic table” for AI
Choosing the right method for multimodal AI—systems that combine text, images, and more—has long been trial and error. Emory physicists created a unifying mathematical framework that shows many AI techniques rely on the same core idea: compress data while preserving what’s most predictive. Their “control knob” approach helps researchers design better algorithms, use less data, and avoid wasted computing power. The team believes it could pave the way for more accurate, efficient, and environmentally friendly AI.
Rams mock draft roundup: L.A. picks Matthew Stafford's heir at QB
With the NFL combine over and free agency a week away, see what experts are saying about LA's two first round picks in the latest mock draft roundup.
Highlighting the top combine efforts from 2026 NFL Draft prospects
Check out some of the best efforts from the NFL Scouting Combine ahead of the 2026 NFL Draft in Pittsburgh.
A Look At Flutter Entertainment’s (NYSE:FLUT) Valuation After Q4 2025 Loss And Softer 2026 Outlook
Flutter Entertainment (NYSE:FLUT) has come under scrutiny after Q4 2025 results combined strong revenue growth with a net loss, softer profitability metrics, and a 2026 outlook that fell short of investor expectations. See our latest analysis for Flutter Entertainment. Flutter’s share price reaction to the Q4 2025 loss and softer 2026 outlook has been severe, with a 30 day share price return of 32.6% decline and a year to date share price return of 49.0% decline. The 1 year total shareholder...
Satwik-Chirag, Ayush Shetty in action at the All England Open Badminton Championship: Indian Sports LIVE, March 4
Here are all the updates from Indian sports on March 4, 2026.
Iowa State discontinues troubled women's gymnastics program
Iowa State is ending its women's gymnastics program. The school's AD called the move "the right decision for our athletics program and our student athletes," citing a pattern of issues within the program.
USA Basketball announces new 3x3 initiative to grow sport
USA Basketball announced a new program Tuesday to bring the international version of 3x3 to young players, programs and gyms around the country.
Lunchbreak: Standout Combine Performances; CBS Sports Ranks Free Agent QBs
Minnesota Vikings Latest News
A New Rookie on Vikings’ Radar
At the NFL Combine, reports rolled in that the Minnesota Vikings had met with Nebraska running back Emmett Johnson, which […]
Kenyon Sadiq named ‘missing piece’ for Eagles offense
With the 2026 NFL Combine in the books, this ESPN personality believes Kenyon Sadiq could be the "missing pieces" of the Eagles' offense.
NFL Writer Identifies Position Steelers Are Seriously Targeting This Offseason
It’s no secret that the Pittsburgh Steelers desperately need to make significant changes to the wide receiver room, and many people around the league understand this. NBC Sports NFL analyst Matthew Berry was at the NFL scouting combine last week and picked up on a lot of buzz surrounding the Steelers, who seemed to be […]
Panthers mock draft roundup 4.0: Tracking the latest 2026 projections
Our post-combine mock draft roundup for the Panthers goes quite heavy on defense.
Rams Mock Draft: Post-NFL Combine edition
Rams 7-round mock draft featuring Combine standouts Kenyon Sadiq, Chris Johnson and more.
State eliminates 8 applicants seeking money for sports facilities upgrades and construction
14 sports facility projects across Ohio, including 3 in Cleveland, are seeking a combined $689 million
Owners of Tigers, Red Wings create regional sports network
Ilitch Sports + Entertainment, who are the owners of the Tigers and Red Wings, have created a regional sports network to broadcast their games.
Matthew Berry’s 35 Most Interesting Things He Heard At 2026 NFL Combine
Matthew Berry reveals the 35 most interesting things he heard at the NFL Combine from a dizzying QB carousel to intriguing RB moves.
Patriots Biggest Offseason Need Revealed Following Combine
The New England Patriots have a clear idea of their offseason needs following the draft combine, according to one insider.
NFL combine grades; UCL bracket; four conference titles clinched
Plus a look at how NFL players graded their coaches in 2025
Albert Breer’s Takeaways: Heeding the Lessons of the Lions’ 2023 Draft Class
NFL scouting combine risers and fallers: LB/DL | DB/TE | QB/RB/WR | OL INDIANAPOLIS — The 2026 NFL combine, my 18th, is now in the books. And we have a little b
2026 NFL mock draft: After combine, a major shake-up throughout first round
Combine action substantially reshaped our latest 2026 NFL mock draft, with major fallout for Jeremiyah Love and others throughout the first round.
NFL Mock Draft 1.0: Building off the Combine
Our first NFL first-round Mock Draft of 2026, reacting to news and workouts from the NFL Combine. What will the Patriots do at No. 31?
Texas A&M OL boosts NFL Draft stock after combine performance
Texas A&M OL Chase Bisontis impressed scouts with his combine performance, boosting his 2026 NFL Draft stock.
Miami Dolphins make decision on Tua Tagovailoa
The NFL Scouting Combine has come to a close, and teams now move towards the new league year. Some teams have tough decisions to make with limited time to do so. The Miami Dolphins, however, appear to have made their…
Deshaun Watson expected to start for Cleveland Browns in 2026
The NFL Scouting Combine is coming to a close, and there have been a number of great performances recorded. There have also been some interesting reports coming out of the combine. Of the teams at the combine, the Cleveland Browns…