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Justice Department tells employees to adopt Trump’s AI rebrand

“This directive shall extend to court filings when appropriate,” the memo titled Super Intelligence states, sources told NBC News.

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Oct 6 • 2:19 PM EDT • Politics • nbcnews.com
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Wolverines Zack Marshall Releases Statement after leaked text messages

On Monday night, there were leaked text messages surfacing across the internet about Michigan Wolverines tight end Zack Marshall being critical of offensive coordinator Jason Beck. Well, Marshall released a statement on his Twitter on Tuesday afternoon and said, What…

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Oct 6 • 2:15 PM EDT • Sports • sports.yahoo.com
Young voters struggle to afford housing. But they don't expect help from political candidates

Pennsylvania's competitive U.S. House districts showcase how housing affordability challenges for young voters may play into control of the next Congress.

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Oct 6 • 2:11 PM EDT • Politics • cnbc.com
Jones Hall celebrates 60 years, renovation completion

Houston First and city leaders celebrated the 60th anniversary and completion of a $67 million renovation of Jones Hall for Performing Arts on Oct. 5.

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Oct 6 • 1:54 PM EDT • Entertainment • communityimpact.com
Black Tooth Business Park Final Plat

The Sheridan City Council met for their first regular business meeting of October Monday night. Sheridan Media’s Ron Richter has the details. A resolution for the final plat of the Black Tooth Business Park located at 3150 Heartland Drive in Sheridan was approved by the Council. City Planner Kelly Schroeder says the applicant, Heartland Assets, […]

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Oct 6 • 1:50 PM EDT • Business • sheridanmedia.com
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Halle Berry denies ex-husband’s claim that she abused their 13-year-old son: ‘I would never hurt our child’

Olivier Martinez accused his ex-wife of abuse last week, asking for sole custody of their son.

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Oct 6 • 1:45 PM EDT • Entertainment • yahoo.com
Location Photo

Each week, on Wednesday, The Journal will post a location challenge photo on its Facebook page, encouraging followers to identify where said location can be found. This week, staffer Tom

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Oct 6 • 1:39 PM EDT • Entertainment • journal-news.net
Michigan tight end Zack Marshall apologizes after he ripped OC Jason Beck in leaked texts
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Oct 6 • 1:32 PM EDT • Sports • sports.yahoo.com
The Jets should change their running back approach

Over the last couple of years, one thing that has frustrated me with the Jets’ approach to offense has been their insistence on using Breece Hall as a do it all back. Hall is a very talented player, but I think it’s clear that he isn’t a complete back. He is an explosive play threat […]

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Oct 6 • 1:14 PM EDT • Sports • sports.yahoo.com
Xbox CEO Asha Sharma speaks at internal town hall — Discussing Xbox Series X|S as 'core,' Helix as a family of devices, boosting Game Pass, and more

EXCLUSIVE: In a recent town hall with Microsoft gaming staffers, Xbox CEO Asha Sharma described how Xbox was in "free fall" declines before this year's big restructure.

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Oct 6 • 1:02 PM EDT • Technology • windowscentral.com
CD&R, McKesson acquiring infusion therapy provider Option Care Health for $5.8B

Option Care Health, a provider of infusion therapy services, is being acquired by private equity firm CD&R and healthcare conglomerate McKesson in a deal valued at $5.8 billion, the companies a | Option Care Health, the country's largest independent provider of at-home and alternate site infusion services, would go private in the deal, which is expected to close in the first half of 2027.

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Oct 6 • 12:30 PM EDT • Health • fiercehealthcare.com
Pacers Given Interesting Win Total Despite Tyrese Haliburton Return

The Indiana Pacers have been given an interesting win total prediction entering the new NBA season.

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Oct 6 • 12:15 PM EDT • Sports • sports.yahoo.com
Pacers' Tyrese Haliburton Already 'Enjoying Playing' With Ivica Zubac

Indiana Pacers guard Tyrese Haliburton is already having fun playing with center Ivica Zubac.

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Oct 6 • 12:04 PM EDT • Sports • sports.yahoo.com
Health Data Interoperability Still Faces Persistent Barriers

A CRS report says U.S. health data interoperability still faces persistent barriers. Read about the challenges and implications for connected care today.

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Oct 6 • 11:44 AM EDT • Health • legis1.com
Far-right AfD wins first state parliament speaker post

The AfD has become the first far-right party since World War II to secure the post of speaker in a German state parliament. The breakthrough came in Saxony-Anhalt after the party's landslide election victory last month.

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Oct 6 • 11:12 AM EDT • Politics • dw.com
In Texas governor’s race, Abbott spends big to try to stay in office

Democratic challenger Gina Hinojosa has ramped up her fundraising.

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Oct 6 • 11:00 AM EDT • Politics • washingtonpost.com
Separatists win Quebec local elections

Quebec's separatist Parti Quebecois has returned to power in a minority government. The result revives the issue of Quebec independence and presents a fresh political challenge for Canadian Prime Minister Mark Carney.

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Oct 6 • 11:00 AM EDT • Politics • dw.com
October 2026 Halloween events guide for Eastern Iowa

Looking for the best Halloween events in Eastern Iowa this October? From terror-filled haunts like Circle of Ash to family-friendly parades, library events, and live orchestral concerts, here is your ultimate regional roundup of fall festivities in the Cedar Rapids-Iowa City Corridor.

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Oct 6 • 11:00 AM EDT • Entertainment • thegazette.com
What Nathan Gallagher said in final 'Below Deck' episode before arrest

"Below Deck Mediterranean" cast member Nathan Gallagher talked about his young family's future and overcoming challenges in his final episode before he was arrested and convicted on domestic violence-

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Oct 6 • 10:56 AM EDT • Entertainment • centraloregondaily.com
LOCALIZE IT: As coding boom fades, computer science grads focus on AI skills in choppy job market

Computer science graduates face hiring challenges; artificial intelligence demand is shifting recruitment toward seniors

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Oct 6 • 10:52 AM EDT • Science • lanacion.com.ar
Two lethal doses failed to kill Christa Pike. The science behind a botched US execution

January 1995, when her 19-year-old daughter, Colleen Slemmer, was tortured and murdered.

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Oct 6 • 10:26 AM EDT • Science • timesofindia.indiatimes.com
Scientist who hunts mysterious ghost particles in the Antarctic ice wins Nobel Prize for physics

Francis Halzen said it was predicted that he would win the prize, but the announcement still made him feel “strange.” The 82-year-old scientist is affiliated with the University of Wisconsin–Madison in the U.S.

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Oct 6 • 10:20 AM EDT • Science • latimes.com
Top Republican super PAC pledges $5 million for South Carolina Senate race

The Senate Leadership Fund’s commitment comes amid a tight contest between GOP Sen. Darline Graham and Democratic challenger Annie Andrews.

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Oct 6 • 10:12 AM EDT • Politics • nbcnews.com
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Brazil: Lessons from a Disaster

By Antonio Martins (Outras Palavras) Defeats become deeper and more prolonged when we misunderstand what caused them, avoid correcting course, and embrace “solutions” that only compound our mistakes. Lula’s government and the Brazilian left suffered a disaster in Sunday’s election. Contrary to every poll, the president finished the first round 2.2 million votes behind Flávio Bolsonaro—and, more significantly, 3.4 million votes below his total four years ago, when the machinery of the state was working against him and in favor of his opponent. His vote share declined in 98 percent of Brazil’s municipalities. The PL, the main party of the far right, elected 121 deputies and 28 senators, becoming the largest caucus in both houses of Congress. The parties aligned with the Centrão—Brazil’s bloc of transactional center-right parties—were somewhat diminished, but will still hold roughly 250 seats in the Chamber of Deputies and 35 in the Senate. That will make it easier to assemble the majorities needed to amend the Constitution or impeach Supreme Federal Court justices. If elected, Flávio Bolsonaro could appoint four members of the Court, substantially altering its internal balance of power. What produced these results? How can the far right be prevented from consolidating them into a prolonged political hegemony? And what is the essential change of direction the left now needs? Explaining the Disaster Across the commercial media and the exuberant chaos of digital platforms, interpretations are multiplying. Some focus on specific episodes: Lula’s absence from the Globo debate, his very close relationship with Alexandre de Moraes, or his emphasis on issues supposedly remote from most people’s everyday concerns, such as rare earth minerals. Among the more systemic interpretations, three seem especially questionable. One argues that the principal defeat was not the left’s, since its congressional representation declined only slightly. The decisive movement captured at the ballot box, according to this view, was a shift within the right itself—from the more moderate and transactional forces of the Centrão toward the more ideological and radicalized forces of the PL and Novo. A second interpretation holds that the nature of electoral and political processes has changed. The material interests and aspirations of society, it argues, no longer play the central role they once did; they have given way to forms of subjective self-identification that the left has yet to understand. And a third concludes that, because of these two developments, we should expect a political winter: a prolonged period in which the far right and the broader right dominate Brazilian political life. There are important elements in all three interpretations. The problem lies in what they deny or leave out: Lula’s third government was a small-bore government. It offered the majorities that elected it neither a clearly better life nor reasons to believe again in politics and its power to transform society. These failures flowed from two fatal accommodations, which I will examine below. As a result, the government suffered a slow but steady erosion of support. And, as has happened in so many Western countries, it gave the far right the opportunity to present itself as anti-system and to benefit from popular frustration and distress. The interpretation that emphasizes the migration of votes from the center-right and traditional right toward the far right has been advanced, among others, by the courageous journalist Leonardo Sakamoto. In his UOL column on Monday, October 5, he highlights the miserable behavior of the traditional conservative parties. Over the past four years, they repeatedly joined forces with the “neo”-fascists, helping to “normalize” them—a criticism that could equally be directed at almost the entire corporate media. Believing they could use the far right as a stepping stone, they instead ended up partly devoured by it. This was especially true in the Senate, where the PL’s gain of 13 senators and Novo’s gain of two came at the expense of the PSD, which lost nine; the MDB, which lost two; the PSDB, which lost two; and the PP, which lost one. Sakamoto’s observation is accurate and necessary, but it leaves uncomfortable questions unanswered. Why did the erosion of the Centrão benefit the far right rather than, for example, producing growth for the left—as has happened so many times before, both in Brazil and elsewhere? The answer is not difficult. Throughout its four years in office, Lula’s third government was almost invariably associated with the Centrão. Here lies its first accommodation: accepting the limits imposed by conservative institutions; avoiding, as much as possible, any attempt to strain those limits through popular pressure; and believing only in the modest changes that could be squeezed through openings in Congress. The failure of the campaign to end the six-day workweek is emblematic. Lula could have electrified the presidential race by pairing it with a popular campaign for passage of the measure. Instead, he chose to place his hopes in the hands of Senate president Rodrigo Alcolumbre. He generated no mass mobilization, did not force his opponents onto an uncomfortable defensive, and won no victory. In September 2025, the government squandered the greatest of its many opportunities to shake up conservative power in Congress. Popular opposition to the so-called Shielding Amendment—which, if approved, would have restricted criminal proceedings against members of Congress—brought crowds into the streets, mobilized primarily by artists and social movements. This opened the possibility for a broader political education: a campaign that could begin exposing the limits and dysfunctions of Brazil’s political system while putting Bolsonaro’s movement on the defensive for its predictable support of political privilege. The amendment was defeated. But the executive branch then backed away from the fight. It remained associated with an institutional world widely seen as corrupt, elitist, and indifferent to ordinary people’s struggles. In doing so, it forfeited its credibility as a vehicle for the protest vote. On Sunday, it reaped the bitter fruits. Are We Doomed? Taking a different approach from Sakamoto, the philosopher Moysés Pinto Neto and other writers have drawn attention, in their first analyses of October 4, to the fragmentation of the public sphere produced by Big Tech platforms. Through their algorithms, these platforms present each person with a different view of social reality. As a consequence, it becomes much harder to identify common material problems and demands—for example, the fight for labor rights or for a properly funded public health system. Voters no longer embrace such demands, these authors argue, because they no longer see themselves as part of a collective. Instead, they tend to value the identities assigned to them by neoliberal subjectivity—the role of the entrepreneur, for example. On this interpretation, the left’s possible error lies in clinging to outdated illusions. Moysés’s warning is highly relevant and resonates with arguments such as Naomi Klein and Astra Taylor’s “Apocalyptic Fascism and the Billionaires’ Bet.” Unlike a century ago, the far right no longer promises a radiant future. It concentrates instead on resentment—especially that of young men. “They belong to a generation that fears it may never own a home, but compensates with the pleasure it gets from constantly provoking progressives online. Convinced their future has been stolen, they share memes romanticizing historical authoritarian regimes,” the authors write. But Moysés seems to confuse this danger with inevitability. He fails to see that the left’s answer cannot be adaptation. On the contrary, it must strengthen the possibility of politics as collective action. Nor does he recognize that precisely such a reversal is already becoming possible in some of the most promising mobilizations of the twenty-first century: the election, at the end of 2025, of the young Muslim Zohran Mamdani as mayor of New York, on a platform centered on the intensely material fight for an affordable city; the Left Party’s victory in Berlin two weeks ago, built around the demand to expropriate private real-estate corporations; and the very recent wave of demonstrations in Spain—including an occupation of Madrid’s Puerta del Sol—in which tens of thousands of young people mobilized by the Tenants’ Union have demanded limits on rents. By putting itself in the straitjacket of the “fiscal framework” in the first months of 2022, Lula’s third government adopted the second fatal accommodation of its term. Faced with conservative institutions and a country devastated by four years of Bolsonaro, increased public investment was the government’s remaining weapon for offering a more dignified life to the majority and forging an anti-conservative pact with them. The same state that disburses 1 trillion reais a year to enrich a small class of rentiers could instead spend money to extend the Family Health Strategy to every Brazilian, at a cost of 30 billion reais; provide full-day public schooling and childcare to all adolescents and children—and, especially, relief to their mothers; achieve universal sanitation while cleaning up polluted urban rivers; multiply metro systems; begin transforming the urban peripheries; and undertake many other urgently needed projects. In April 2023, an article in Outras Palavras warned that the fiscal framework could “shrink the Lula government and preserve the forces that condemn the country to inequality and regression.” A year later, another article showed that restraints on public spending were strangling policies vital to ordinary people and undermining the president’s popularity. In November 2024 came a reality check, in the form of the government’s humiliating defeat in the municipal elections. Even then, the fiscal lock was neither removed nor loosened. On the contrary: throughout the government’s four years, fiscal restraint remained central to its political narrative. The administration proudly proclaimed that it had “put the state’s accounts in order,” without grasping either how misleading that phrase was—given the payment of 1 trillion reais in interest—or how badly the message was hurting it politically. Lula finally woke up in September 2026. The increase in Bolsa Família benefits, after four years of being frozen; the announcement that anti-obesity drugs would be offered through Brazil’s public health system; and the ban on online betting showed that the state has the power to act decisively on behalf of the majority when those in government are willing to confront obstacles. The huge marches that closed the campaign in Fortaleza, Salvador, Rio de Janeiro, and São Paulo on the eve of October 4 showed how such initiatives can mobilize activists and the broader public. But it was too late—and too little to change the outcome of the first round. History has not ended The possibility of a turnaround in the three weeks leading up to November 25 cannot be ruled out. It will not be simple or easy. Lula must not only make up a deficit of 2.2 million votes; he must also offset the movement of voters who backed other right-wing candidates in the first round, most of whom are likely to move toward Flávio Bolsonaro. Pulling that off will require a broad, grassroots effort to win over voters, potentially reinforced by new initiatives from Lula. The coming hours and days will be decisive. If Bolsonaro’s movement also wins the presidency, the result will create a high-risk situation for Brazilian sovereignty and democracy. The enormous challenges posed by such an outcome would require the left to reexamine, in depth and with a genuine willingness to engage in self-criticism, its political projects—or its lack of them—and its practices. But would that mean we are condemned to the long winter of far-right hegemony that some analyses are beginning to forecast? It is far too early to say, suggests a recent text by Álvaro García Linera, the thinker who served as vice president of Bolivia under Evo Morales. His central hypothesis is that this political current will prove short-lived. At a moment when the entire world is once again talking about sovereignty and protecting national economies, the far right offers a stale, recolonizing neoliberalism. Its submission to the United States is as blatant and pathetic as Flávio and Eduardo Bolsonaro’s overtures to Donald Trump. Its project amounts to something like every man for himself: greater inequality, capitalism without limits, devastation, and supremacism. Will it work? In the United States, just two years into his second term, Trump himself is reaching record levels of unpopularity and may be on the verge of losing Republican control of both the House and Senate in November. Every new beginning is difficult. Whatever the outcome of the second round, the defeats of October 4 show how profoundly the Brazilian left will have to rethink and rebuild. But just as it would be foolish to underestimate the seriousness of its mistakes, it would be equally foolish to conclude that rebuilding a political project is no longer possible. History has not ended. The times are moving faster than ever. Originally published in Portuguese by Outras Palavras. English translation by Eric Blanc; I’ve added the subtitles. More We can’t stop the far right at home or abroad without a revitalized labor movement, which is yet another reason why you should become a sustaining supporter of the Emergency Workplace Organizing Committee (EWOC) — one of US labor’s pivotal bright spots. Relatedly, Jacobin published a short piece of mine reflecting on a decade of Bernie Sanders inspiring a whole new generation of young worker organizers.

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Oct 6 • 10:08 AM EDT • Politics • laborpolitics.com
Los Angeles Chargers news: Would you trade Khalil Mack?

If this Chargers season is deemed a lost cause, should they think about trading away Khalil Mack while he’s valuable?

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Oct 6 • 9:52 AM EDT • Sports • sports.yahoo.com
StoneX maintains Buy rating on Sphere Entertainment, $125 price target

StoneX maintained their Buy rating on Sphere Entertainment's stock with a price target of $125.00.The price target implies an upside of 12.8% from the Oct 5 close of $110.80.Key takeaways from the analyst noteLong-Term Growth Potential: Despite recent challenges, Sphere Entertainment is expected to…

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Oct 6 • 8:36 AM EDT • Entertainment • tradingview.com
Francis Halzen wins Nobel Prize in Physics for work on ‘ghost particles’
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Oct 6 • 8:31 AM EDT • Science • aljazeera.com
Francis Halzen wins Nobel Prize in physics for work on ghost particles

The Nobel Committee praised his work at the IceCube Neutrino Observatory in Antarctica, where he began studying neutrinos in the 1980s

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Oct 6 • 8:19 AM EDT • Science • spectrumlocalnews.com
Francis Halzen wins Nobel Prize in physics for work on ghost particles

The Nobel Committee praised his work at the IceCube Neutrino Observatory in Antarctica, where he began studying neutrinos in the 1980s

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Oct 6 • 8:19 AM EDT • Science • spectrumlocalnews.com
The Kids in the Arena: Spectrum Business Keeps Florida Esports Facility Connected

With Spectrum Business Internet Gig, Valhallan Esports Training now has reliable high-speed, low-latency connectivity so young gamers have a safe, supportive environment to play their favorite games.

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Oct 6 • 8:00 AM EDT • Business • corporate.charter.com
Sun Life research reveals the ripple effect behind small business success

As Canada's small businesses navigate a rapidly changing business environment, new research from Sun Life shows that success is about more than growing revenue. It's about building resilience. When owners feel confident in their ability to weather challenges and plan for the future, they're more likely to invest in their employees, strengthen their businesses and create lasting impact for the people who depend on them. The findings align closely with how Sun Life supports small business owners,

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Oct 6 • 8:00 AM EDT • Business • finance.yahoo.com
Buffalo Bills’ Josh Allen-led offense takes a sloppy step back

Buffalo’s offense hasn’t so much dried up in splitting the past two games, it’s shown signs of sputtering and being impeded by ball-security issues.

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Oct 6 • 7:26 AM EDT • Sports • spectrumlocalnews.com
Arsenal star in contention for Golden Boy 2026 award

Myles Lewis-Skelly is among the leading Premier League youngsters nominated for the 2026 Golden Boy award, after reclaiming his place in the Arsenal and England teams.During the second half of last se...

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Oct 6 • 7:00 AM EDT • Sports • sports.yahoo.com
Iowa's 3rd Congressional District candidates sound off on economy, war

Republican U.S. Rep. Zach Nunn faces a challenge from Democrat Sarah Trone Garriott in the Nov. 3 midterm election. Meet the candidates.

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Oct 6 • 6:33 AM EDT • Politics • desmoinesregister.com
As Halo Moves to Activision, Halo Studios Writers Tease What Might Have Been

Following the launch of Halo: Campaign Evolved, Halo Studios has put out a blog post detailing plans for the future of Master Chief’s story. It’s an interesting look at where the series might have gone, prior to the recent announcement that Activision is now the shepherd of the Halo series.

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Oct 6 • 6:18 AM EDT • Technology • ign.com
Francis Halzen wins Nobel Prize in physics for work on high-energy neutrinos from space

The 82-year-old scientist, originally from Belgium, is affiliated with the University of Wisconsin–Madison. His research into capturing neutrinos at the South Pole dates back to the 1980s.

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Oct 6 • 6:16 AM EDT • Science • npr.org
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Nobel prize in physics goes to Francis Halzen for south pole work on neutrinos

Belgian physicist praised for work on the IceCube detector that observes the ghost-like particles in Antarctica

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Oct 6 • 6:11 AM EDT • Science • theguardian.com
'Ghost particles' from space telescope wins 2026 Nobel Prize in Physics

Belgian physicist Prof Francis Halzen has won for his pioneering work on an observatory that detects particles from space.

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Oct 6 • 6:10 AM EDT • Science • bbc.com
Mental Health Resource Fair coming to Victorville

The city of Victorville will partner with San Bernardino County agencies and regional service providers to host a Mental Health Resource Fair.

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Oct 6 • 6:04 AM EDT • Health • vvdailypress.com
Francis Halzen wins 2026 Nobel Prize in physics

Among past laureates are some of the most celebrated figures in science, including Albert Einstein, Marie and Pierre Curie, Max Planck and Niels Bohr.

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Oct 6 • 6:02 AM EDT • Science • japantimes.co.jp
Deion Sanders created Prime Time so he could get paid. Why deny college athletes the same chance?

The Hall of Famer says his successful college career helped him and his family thrive. Now he appears to be backing legislation that would help others

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Oct 6 • 6:00 AM EDT • Sports • theguardian.com
Nobel Prize in physics awarded to Francis Halzen for his work detecting cosmic particles

The 2026 Nobel Prize in physics has been awarded to Francis Halzen for his “decisive contributions to the IceCube Neutrino Observatory and the discovery of high-energy neutrinos of astrophysical origin.”

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Oct 6 • 5:54 AM EDT • Science • cnn.com
Nobel Prize in Physics awarded to Francis Halzen for ice research

Scientist Francis Halzen won the 2026 Nobel Prize in Physics, the Royal Swedish Academy of Sciences in Stockholm announced on Tuesday.

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Oct 6 • 5:52 AM EDT • Science • france24.com
Francis Halzen wins 2026 Nobel Prize in Physics

Belgian-American Particle physicist Francis Halzen won the 2026 Nobel Prize in Physics for "decisive contributions to the IceCube Neutrino ​Observatory and the discovery of high-energy neutrinos of astrophysical origin", the award-giving ‌body said on Tuesday.

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Oct 6 • 5:51 AM EDT • Science • reuters.com
Tuesday ‘Dawg Bites Isn’t Anxious… Yet

Welcome to Tuesday, Bulldog fans! And it’s week 6… the halfway point of the regular season. At this juncture, I believe we all thought we’d know exactly where the 2026 Georgia team stood in the national conversation, because the team would have faced 2 lower division opponents, a rebuilding SEC team, an SEC team that […]

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Oct 6 • 5:30 AM EDT • Sports • sports.yahoo.com
After devastating fire, what's next for downtown Walhalla?

A fire destroyed six businesses in downtown Walhalla, leaving owners and residents seeking a path forward.

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Oct 6 • 5:03 AM EDT • Business • greenvilleonline.com
Penn State College Of Health & Human Development Launches New Public Health Major

The new major will prepare students for global health challenges, preventative measures, and more.

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Oct 6 • 4:01 AM EDT • Health • onwardstate.com
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Climate Science Under Political Attack Reaches US Supreme Court

In 2018, local officials in Colorado sued oil companies in state court, charging that pollution from fossil fuels contributed to global warming and harmed

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Oct 6 • 12:45 AM EDT • Science • insurancejournal.com
Quebec separatists win power in new challenge for Canada’s Carney

Voters in Quebec elected a separatist political party for the first time in more than a decade, setting the stage for more strained relations with Prime Minister Mark Carney’s government

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Oct 5 • 10:32 PM EDT • Entertainment • thederrick.com
Monday Night Football: Bijan Robinson has Falcons leading 24-7 at halftime
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Oct 5 • 9:59 PM EDT • Sports • sports.yahoo.com
Hall of Famer Jason Kidd close to joining ESPN as NBA analyst, per reports
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Oct 5 • 9:54 PM EDT • Sports • sports.yahoo.com
St. Louis Cardinals Biggest 2027 Challenge? Managing Expectations

I have been a St. Louis Cardinals fan for more than five decades and I have lived through many different eras of losing seasons, championships and everything in between. I can’t recall any of them being more unclear about what the expectations should be for an upcoming season than the one that will hopefully begin […]

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Oct 5 • 9:50 PM EDT • Sports • sports.yahoo.com
Relatives of Epstein victim appear in attack ad targeting Jeff Crank

Relatives of Virginia Giuffre, one of Jeffrey Epstein‘s most prominent victims, accuse U.S. Rep. Jeff Crank in a TV ad released Monday by his Democratic challenger of refusing to meet with them last year when they sought his assistance to force a vote to release federal files related to the convicted sex offender. Sky and […]

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Oct 5 • 8:56 PM EDT • Politics • coloradopolitics.com
Xbox sale round-up October 6, 2026

New Xbox sales are now live, with big discounts on Halo Wars 2, Dead Cells, Sid Meier's Civilization Revolution, Batman: The Telltale Series, The Gunk, Batman: The Enemy Within - The Telltale Series, The Escapists and more

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Oct 5 • 8:19 PM EDT • Technology • trueachievements.com
Nobel Prize in Physics 2026

The Nobel Prize in Physics 2026 was awarded to Francis Halzen “for decisive contributions to the IceCube Neutrino Observatory and the discovery of high-energy neutrinos of astrophysical origin.”

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Oct 5 • 8:00 PM EDT • Science • nobelprize.org
Countries race to provide oral health care for all in 100-Day Sprint across Asia

Twenty Asian countries and areas across the WHO Western Pacific and South-East Asia regions vowed to strengthen essential oral health benefits as part of a “100-Day Sprint” initiative, during the 16th Asian Chief Dental Officers Meeting held from 27 to 29 September in Kota Kinabalu, Malaysia. The meeting marked the midpoint of the 100-day sprint bolstering support for countries to develop essential oral health benefit packages that can be integrated into national universal health coverage plans. Convened by the two WHO regional offices and the Malaysian Ministry of Health as the Secretariat, the meeting brought together national oral health leaders from 20 Asian countries, staff from all levels of WHO, WHO collaborating centres and other development partners. Participating countries and areas included: Bangladesh, Bhutan, Brunei Darussalam, Cambodia, China, Hong Kong (SAR) China, India, Indonesia, Japan, Lao People’s Democratic Republic, Malaysia, Maldives, Mongolia, Nepal, the Philippines, Singapore, Sri Lanka, Thailand, Timor-Leste and Viet Nam. Participants reviewed progress and refined proposals using the WHO Service Package Delivery and Implementation (SPDI) Platform. Countries conducted bottleneck analyses across four key areas: service delivery, workforce, access to essential medicines and health products, and health financing. They identified practical actions to address implementation challenges and refined proposed revisions to their national oral health benefit packages. “There is no health without oral health. Through the 100-Day Sprint, countries are advancing the implementation of the Western Pacific regional implementation plan on oral health and strengthening progress towards universal health coverage,” noted WHO Regional Director for the Western Pacific Dr Saia Ma'u Piukala. Participants identified bottlenecks and proposed workable solutions to strengthen access to essential oral health care through primary health care, sharing experiences and discussing how best to translate policy commitments into feasible and sustainable action at the country level. Malaysian Minister of Health Datuk Seri Dr Dzulkefly Ahmad highlighted the importance of prevention and primary health-care approaches to improve oral health: “Oral diseases can have lifelong consequences, yet many are preventable. By integrating essential oral health care into primary health care and promoting prevention in schools and communities, we can improve oral health across the life course.”The WHO team led by Dr Huong Tran, Director of the Division of Health Promotion, Disease Prevention and Control of the WHO Western Pacific Region and national oral health leads from over 20 Asian countries visited the SK Pekan Putatan School, Sabah for school oral health programme including flouride mouth rinsing. © WHO / V. ChaudharyDr Huong Tran, Director of the Division of Health Promotion, Disease Prevention and Control for the WHO Western Pacific Region, emphasized key collaborative roles WHO can play. “Oral diseases are the most common noncommunicable diseases, yet many can be prevented and treated through essential oral health services delivered at the primary health-care level,” she said. “By sharing experiences and using WHO tools such as the SPDI Platform, countries are accelerating progress towards universal health coverage for oral health.” “Integrating oral health into broader health services is essential for reducing inequities, expanding access and recognizing oral health as an integral component of overall health and well-being. The 100-Day Sprint provides an important opportunity to translate this commitment into practical action and ensure that quality oral health services reach all people, especially those most in need,” said Dr Suman Rijal, Director of the WHO South-East Asia regional Department of Healthier Populations and Noncommunicable Diseases. As host of the meeting, Malaysia showcased ongoing efforts to strengthen oral health care through primary health care and prevention-focused approaches, while providing a platform for countries across the two WHO regions to exchange experiences and accelerate progress towards universal health coverage for oral health. “WHO is encouraged by Malaysia's leadership in addressing the burden of oral diseases and advancing universal health coverage for oral health through practical, country-led action,” said Dr Rabi Abeyasinghe, WHO Representative to Malaysia, Brunei Darussalam and Singapore. Countries will continue to refine and figure costs for national oral health benefits during the remaining sessions of the 100 days. These efforts support implementation of the WHO Global strategy and action plan on oral health 2023–2030, while also helping to expand access to essential oral health services through stronger and more equitable health systems across the WHO Western Pacific and South-East Asia regions.______________For more information, or to arrange media interviews, contact: WHO Regional Office for the Western Pacific: wprocom@who.int WHO Regional Office for South-East Asia: SEMediaRelations@who.int

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Oct 5 • 8:00 PM EDT • Health • who.int
Why Sphere Entertainment (SPHR) Stock Is Trading Lower Today

Shares of content production and distribution company Sphere Entertainment (NYSE:SPHR) fell 12.3% in the afternoon session after Craig-Hallum analyst Ryan Sigdahl downgraded the stock from Buy to Hold and reduced the price target to $132 from $170. According to TipRanks, Sigdahl pointed to demand for The Wizard of Oz at Sphere fading faster than expected. The firm cut its estimates to reflect that weaker outlook and lowered its price target to $132 from $170. A reduced target on the show that ha

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Oct 5 • 7:23 PM EDT • Entertainment • finance.yahoo.com
The Sticky Business of Loving Cinéma L’Amour: Inside Montreal’s Historic Porn Theater

You won’t find a sexier testament to word-of-mouth marketing than this Canadian institution, where free online porn and Trump’s tariffs are among many challenges facing its warmly exhausted owner toda...

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Oct 5 • 6:30 PM EDT • Business • yahoo.com
Cargill’s earnings slump 52% with high cattle costs, cocoa loss

Cargill Inc.’s fiscal first-quarter earnings fell by more than half as the largest private company in the U.S. was pressured by higher costs for cattle and cocoa despite also benefiting

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Oct 5 • 5:57 PM EDT • Entertainment • thederrick.com
Cincinnati nuisance business rules for late-night bars face fierce opposition

A proposed crackdown on Cincinnati’s so-called nuisance businesses has put City Hall at odds with some late-night bar and nightclub owners.

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Oct 5 • 5:38 PM EDT • Business • local12.com
Knicks’ 3 Most Intriguing Regular Season Matchups

As the regular season approaches, the Knicks will officially go from the hunters to the hunted. After a wild offseason, especially in the significantly strengthened Eastern Conference, the defending champions will face much tougher challenges this season. Teams in the East like the Miami Heat, Toronto Raptors, and Philadelphia 76ers all made moves to strengthen …

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Oct 5 • 5:24 PM EDT • Sports • sports.yahoo.com
Hawkeye Women Land Athletic Center Khalia Hartwell From 2027 Class

Fans of Iowa women’s hoops should be very excited about some of the recruits that are saying yes to the black and gold in the post Caitlin Clark era. Jan Jensen has had some of the very best high school players expressing serious interest in Iowa and has convinced a few of them to commit. […]

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Oct 5 • 5:00 PM EDT • Sports • sports.yahoo.com
This is Apple Music’s new logo, probably

Apple Music seems to be rolling out a new logo, as spotted in several places including iOS 27 beta 3, Apple Music Hall branding, and more.

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Oct 5 • 4:50 PM EDT • Technology • 9to5mac.com
Fall Preview with Entertainment Correspondent Mike Marra

Airdate: October 5th, 2026 Leoni Township Update with Administrator Mike JesterOctober 5, 2026City Treasurer Hosting Town Hall Meeting SeriesOctober 5, 2026Tecumseh Appleumpkin Festival This WeekendOctober 5, 2026Fall Preview with Entertainment Correspondent Mike MarraOctober 5, 2026Disney’s Frozen Premieres Thursday at The SaukOctober 5, 2026Alison McGlynn & Lilly Hayworth, The Annex Collective SalonOctober 5, 2026John Spink, Nite…

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Oct 5 • 4:28 PM EDT • Entertainment • jtv.tv
Send us your questions for Texas Senate candidate James Talarico

Calling all Texas Republicans, Democrats, and Independents! Are you a registered voter in Texas? Then submit questions for CNN & Jubilee’s Town Hall with James Talarico on Wednesday, October 14 and engage in a direct conversation with the Texas Democratic Senate candidate on the issues that matter most to you.

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Oct 5 • 4:20 PM EDT • Politics • cnn.com
Richland County Mental Health & Recovery Services Board selects Aubrie Hall new director

Aubrie Hall most recently served as executive director of NAMI Richland County, a post she held for two and a half years.

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Oct 5 • 4:15 PM EDT • Health • richlandsource.com
Mail mystery: Astoria businesses, City Hall report spotty delivery, missing packages

Inconsistent mail delivery in Astoria has attracted the attention of Oregon's U.S. senators, especially as midterm elections near.

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Oct 5 • 3:50 PM EDT • Business • opb.org
Chip City closes all locations amid economic challenges

Chip City, a New York City-based gourmet cookie chain, has closed all 22 remaining locations nationwide due to tough consumer spending and evolving preferences.

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Oct 5 • 3:47 PM EDT • Business • libn.com
Bladen Community College to host “So You Want to Start a Small Business” class and preview Pitch It Bladen 2027

The Small Business Center at Bladen Community College invites aspiring entrepreneurs to attend “So You Want to Start a Small Business” on Tuesday, Oct. 13, 2026, from 6:00 p.m. to 8:00 p.m. in Building 14, Room 104. This class will help participants explore what it takes to become an entrepreneur and take the first steps toward turning a business idea into reality.Participants will explore the entrepreneurial mindset and consider whether they have the interests, characteristics, motivation and willingness to take on the challenges of business ownership. The class will encourage attendees to examine their personal goals, expectations, strengths and readiness to pursue entrepreneurship.Attendees will also gain insight into the realities of starting and operating a small business, including the commitment, planning, decision-making and perseverance required to build a successful venture. Whether participants are just beginning to consider business ownership or already have an idea they want to pursue, this class will provide a foundation for determining their next steps.In addition to the class instruction, attendees will receive advance information about the upcoming Pitch It Bladen 2027 Business Competition, including the application form and details about the program. Individuals who are ready to move forward may submit their applications early and have the opportunity to receive advance acceptance into the program.Pitch It Bladen helps aspiring and emerging entrepreneurs develop their business ideas through structured instruction in business planning, financial management, cash-flow projections, marketing and operations. Participants work toward completing a business plan and preparing a business pitch, with the opportunity to compete for cash prizes.Last year's Pitch It Bladen program demonstrated the value of investing in local entrepreneurs by helping participants strengthen their business knowledge, develop their business plans and prepare to present their ideas. The competition showcased the creativity and potential of Bladen County's small-business community and provided participants with practical tools to move their business goals forward.Building on that success, Pitch It Bladen 2027 will provide another opportunity for local entrepreneurs to gain knowledge, build confidence and take meaningful steps toward launching or growing a business.“The Small Business Center wants to help individuals make informed decisions about entrepreneurship before they take the leap into business ownership,” said Theresa Dennison, Small Business Center director, in a press release. “This class gives participants an opportunity to evaluate whether entrepreneurship is right for them while also introducing them to Pitch It Bladen 2027 and the resources available to help them succeed.”Registration: Visit www.ncsbc.net and search for the class by name, or contact the Small Business Center at 910-879-5572 for additional information.

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Oct 5 • 3:26 PM EDT • Business • bizfayetteville.com
Overwatch Season 5 skins and Mythics Revealed by Blizzard

Get ready for a spooky season in Overwatch

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Oct 5 • 3:13 PM EDT • Technology • polygon.com
CAS inducts seven into Hall of Fame

The College of Arts and Sciences (CAS) inducted seven distinguished members of the CAS community into its Hall of Fame on Friday, September 18.

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Oct 5 • 2:57 PM EDT • Science • news.illinoisstate.edu
Viral Dallas mansion gets political with this year's Halloween display

A Preston Hollow mansion known for viral holiday displays has unveiled a political Halloween display that backs Ken Paxton, targets James Talarico and calls out Dallas Councilwoman Gay Donnell Willis.

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Oct 5 • 2:32 PM EDT • Politics • fox4news.com
Newcastle gets $25M refinancing for West Loop apartments

Refinancing can be a challenge in today’s elevated interest rate environment, but Northmarq said the process was competitive because of strong lender appetite for apartment buildings.

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Oct 5 • 2:20 PM EDT • Business • chicagobusiness.com
‘The Batman Part II’ halts production as director Matt Reeves steps away for personal reasons

After years of delays, ‘The Batman Part II’ has ‘temporarily paused’ production as director Matt Reeves ‘focuses on a family matter.’

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Oct 5 • 2:13 PM EDT • Entertainment • ew.com
After redistricting, a Black community in Louisiana faces a future without a champion in Congress

Scotlandville is a predominantly Black community in Louisiana, that's facing challenges in its political representation. Residents fear losing a representative who understands their struggles.

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Oct 5 • 2:06 PM EDT • Politics • pbs.org
Why Sphere Entertainment (SPHR) Stock Is Trading Lower Today

What Happened? Shares of content production and distribution company Sphere Entertainment (NYSE:SPHR) fell 12.3% in the afternoon session after Craig-Hallum ...

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Oct 5 • 1:25 PM EDT • Entertainment • stockstory.org
Carnell Tate Not Letting First-Half Blunder Ruin Historic Day

The rookie receiver overcame a costly turnover to deliver a dominant 145-yard performance, signaling a new era of offensive consistency for Tennessee despite a narrow loss.

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Oct 5 • 1:00 PM EDT • Sports • sports.yahoo.com
Pokémon GO Halloween 2026: Part One

Pokémon GO’s Halloween 2026 Part One event runs from October 27 at 10:00 a.m. to November 1 at 10:00 a.m. local time, bringing three new costume Pokémon: Pikachu wearing a hat and capelet, Zubat wearing a top hat, and Sinistea wearing a bow! Expect spooky wild encounters, costume raids, and trick-or-treat surprises that can reward […]

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Oct 5 • 12:55 PM EDT • Technology • pokemongohub.net
Angels To Face Decision On Ill-Fitting First Baseman

Nolan Schanuel’s elite contact skills contrast sharply with a glaring lack of power, forcing the Halos to weigh his high-floor production against more traditional middle-of-the-order threats.

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Oct 5 • 12:21 PM EDT • Sports • sports.yahoo.com
Astronomers discover possible planet born from a dead star’s ashes

A second-generation planet might be orbiting a white dwarf, in an astronomy first, according to new research.

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Oct 5 • 11:58 AM EDT • Science • cnn.com
'Flew Here Grew Here' talks trending entertainment topics

Olivier Martinez claims Halle Berry assaulted their 12-year-old son, Maceo, alleging she choked him and yelled "Who is dominant now?"

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Oct 5 • 11:34 AM EDT • Entertainment • fox5atlanta.com
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Health care aide charged in assault of disabled resident at Halfmoon facility

A Schenectady woman working as a health care aide has been charged after State Police said a disabled resident was assaulted at a Halfmoon care facility.

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Oct 5 • 11:24 AM EDT • Health • cbs6albany.com
Fear is bigger than ever… and Zero Latency VR has the science to prove it

MELBOURNE, Australia — Zero Latency VR, the world’s largest and most innovative immersive VR network, is celebrating a double Halloween anniversary: three years since the launch of Outbreak, …

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Oct 5 • 10:56 AM EDT • Science • amusementtoday.com
Can Democrats expand their Senate map?

Plus: Will Ken Paxton's estranged wife help him win?

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Oct 5 • 10:47 AM EDT • Politics • usatoday.com
Florida's Jadan Baugh Has Another Tough Challenge Against South Carolina

After Missouri stifled the Heisman frontrunner, the Gators must revive their ground game against a relentless Gamecocks front to avoid a devastating mid-season collapse in Columbia.

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Oct 5 • 10:40 AM EDT • Sports • sports.yahoo.com
How former Cyclones performed in Week 4 of the NFL

Ten former Cyclones made appearances in Week 4 of the NFL and played a combined 543 snaps on offense, defense and special teams. Breece Hall – New York Jets Hall did not play against the Chicago Bears due to a quad injury sustained during the Lions game in week three. Jake Hummel – Houston Texans Hummel […]

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Oct 5 • 10:33 AM EDT • Sports • sports.yahoo.com
Luke Fickell's 'vision' starting to show, Joe Thomas says

After the Wisconsin Badgers dominated Michigan State on Saturday, Hall of Famer Joe Thomas broke down the team's progress.

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Oct 5 • 10:30 AM EDT • Sports • captimes.com
Supreme Court rejects appeal over Michigan school's ban on ‘Let’s Go Brandon’ sweatshirts

The Supreme Court is rejecting an appeal from a Michigan woman challenging a school district’s ban on shirts with the phrase “Let’s Go Brandon.” | 830 WCCO

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Oct 5 • 9:59 AM EDT • Politics • audacy.com
Supreme Court rejects appeal over Michigan school ban on ‘Let’s Go Brandon’ sweatshirts

The Supreme Court is rejecting an appeal from a Michigan woman challenging a school district’s ban on shirts with the phrase “Let’s Go Brandon.” | KNSS Radio

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Oct 5 • 9:59 AM EDT • Politics • audacy.com
First DLC for ‘Halloween: The Game’ Arrives October 27, Featuring a Free ‘Halloween 5’ Map

As expected, the first DLC for IllFonic's 'Halloween: The Game' will arrive just in time for Halloween on October 27.

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Oct 5 • 9:30 AM EDT • Technology • bloody-disgusting.com
Sphere Entertainment (NYSE:SPHR) Downgraded by Craig Hallum to "Hold"

Craig Hallum lowered Sphere Entertainment from a "buy" rating to a "hold" rating and set a $132.00 price objective for the company. in a research report on Monday.

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Oct 5 • 9:06 AM EDT • Entertainment • marketbeat.com
Business Beat : Halloween activities planned at the Branch County Fairgrounds

COLDWATER, MI (WTVB) - The Branch County Fairgrounds will host a pair of family-friendly Halloween events this...

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Oct 5 • 8:09 AM EDT • Business • wtvbam.com
Innovation That Solves: From Business Needs to AI Solutions

Targeted AI innovation transforms business challenges like hydrocarbon compliance into effective technological solutions, writes Jorge Mandujano.

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Oct 5 • 8:00 AM EDT • Business • mexicobusiness.news
The Economics of Delta Healthcare

How well is the system? Experts weigh in on status While agriculture rightfully gains most of the headlines when it comes to the Delta’s economy, the role of healthcare in the region cannot be underestimated. Many challenges face healthcare providers in the region and the state recently stepped in to assist. Nonetheless, healthcare leaders in […]

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Oct 5 • 7:54 AM EDT • Business • deltabusinessjournal.com
Integral Ad Science to Provide Brand Safety and Suitability Measurement in ChatGPT Ads

NEW YORK, October 05, 2026--As artificial intelligence rapidly reshapes digital advertising, marketers face a critical new challenge: ensuring brand safety and suitability within dynamic, generative AI-native environments. Without independent verification, advertising in conversational channels risks creating a blind spot for enterprise brands seeking reliable media quality standards.

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Oct 5 • 7:00 AM EDT • Science • finance.yahoo.com
Sexual misconduct allegations threaten to topple veteran LA Democrat

LA Democrat Jimmy Gomez is facing a strong socialist challenger.

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Oct 5 • 7:00 AM EDT • Politics • sfgate.com
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth

Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine

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Oct 5 • 6:44 AM EDT • Science • goldrushcam.com
Bob Kustra and Jenny Kustra-Quinn: The time for keeping beluga whales captive for our entertainment has passed

There is no legitimate reason for us to deprive belugas of the right to flourish.

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Oct 5 • 6:00 AM EDT • Entertainment • chicagotribune.com
Study: IL lawyers report mental health challenges, substance abuse, suicide ideation

(CAPITOL CITY NOW) - For many lawyers, the effects of the job can include declining mental health, substance abuse, problem gambling, suicide ideation, and even declining cognitive skills. These are the results of a survey of Illinois attorneys, "The Weight of Practice," commissioned by the Illinois Lawyers' Assistance Program. Factors include the stress of being

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Oct 5 • 6:00 AM EDT • Health • capitolcitynow.com
The challenge of measuring clinical value in mental health

Clients need assurances that high-cost medications flooding the system are aligned with the clinical support needed to improve mental health.

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Oct 5 • 5:30 AM EDT • Health • benefitnews.com