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10 things you can do every day to support your brain health
Many health factors can influence brain function later in life, according to the Alzheimer's Association's annual report. Here's what to know.
First Louisiana patient to receive sickle cell gene therapy heads home after 6 weeks in hospital
Learn about the groundbreaking gene therapy for sickle cell disease at Manning Family Children's Hospital in Louisiana, providing hope for a "functional cure".
Trump Terminates Entire National Science Board
govern the National Science Foundation (NSF). The National Science Board directs and approves large funding decisions for NSF’s approximately $9 billion basic science research budget. It is meant to function independently from the federal administration to keep science funding insulated from political pressure and budget cycles.
'He realised he had beaten me in ‘Sarfarosh’': Nawazuddin recalls moment with Aamir Khan; REVEALS he is fan of Dada Kondke
Nawazuddin Siddiqui has consistently entertained audiences with his distinct and unconventional roles in the film industry. His recent outings, includ.
FTC crackdown pushes auto dealers to treat compliance as a core business function
Industry experts discuss the FTC crackdown, dealer transparency and how compliance, culture and pricing strategy impact M&A and valuation.
A Look At Accel Entertainment (ACEL) Valuation After Recent Share Price Momentum
Recent performance and business snapshot Accel Entertainment (ACEL) has attracted fresh attention after recent share price moves, with the stock showing positive returns over the past week, month and past 3 months, prompting investors to reassess its fundamentals. The company operates distributed gaming terminals, redemption devices with ATM functionality and other amusement equipment in non casino venues across the United States, including restaurants, bars, truck stops and convenience...
Brooklyn College Hosts Urgent Discussion on Black Maternal Health Crisis
The event, attended by students, faculty, staff, and community members, was held in conjunction with the 2026 Perinatal Mental Health Summit at the Greg Jackson Center for Brownsville.
City and EDIC caters to new business
LYNN — When Brita Potenza was looking for space to grow her catering and event-hosting business, she visited the Lydia Pinkham Building and toured the space formerly occupied by Uncommon Feasts. On the wall was a photo of a function that had been held there. She recognized someone. “I looked over on the wall, and […]
Do humanoids dream of becoming human?
Humanoids seem to be evolving into a distinct form.
Leading on health care solutions - Talk Business & Politics
In Arkansas and across the heartland, we are used to solving problems together. That instinct — to step up for our neighbors, to find practical solutions and to work together...
Scientists believe birds’ skulls hold clues to inner lives of long-extinct dinosaurs
Early birds were like ‘T rex reincarnated’, says scientist who believes avian skulls offer insight into dinosaurs’ behaviour
NOLA.com's Live from Jazz Fest: Eating oysters, Rod Stewart vs. David Byrne, weather, more
Catch a feature on Michalopoulos, who has "the distinction of painting more Jazz Fest posters than any other artist." Also an interview with an all-female Mardi Gras Indians group. Today's live show is presented by Explore Louisiana and New Orleans and Company.
The AI Tools Small Businesses Are Using - Small Business & Entrepreneurship Council
By Karen Kerrigan – Artificial intelligence is no longer experimental for small businesses. According to SBE Council’s 2026 Small Business Tech Use Survey, 82% of small business employers have invested in AI tools and they are rapidly being embedded across daily functions and workflows. In fact, AI has become essential to competitiveness and growth as […]
DNA research just rewrote the origin of human species
Scientists have uncovered a surprising new picture of human origins that challenges the long-held idea of a single ancestral population in Africa. By analyzing genetic data from diverse modern African groups—especially the highly distinct Nama people—and comparing it with fossil evidence, researchers found that early humans likely evolved from multiple intermingling populations over hundreds of thousands of years. Rather than a clean split, these groups stayed connected, exchanging genes even after beginning to diverge around 120,000–135,000 years ago.
Aggressive “hulk” lizards are wiping out millions of years of evolution
For ages, wall lizards coexisted in three distinct color types, each with its own strategy for survival. Now, a powerful green variant is taking over. These dominant “Hulk” lizards are outcompeting the others, causing yellow and orange morphs to vanish. It’s a dramatic reminder that evolution can flip the script much faster than expected.
If On Shoes Are for Everyone, Are They Still Ons?
The company finds itself at a critical juncture that others have botched: How does it stay a brand for serious athletes while keeping up its breakneck growth?
Former NCT member Lucas officially ends contract with SM Entertainment
The Hong Kong rapper has since pursued a solo career, releasing the EP Renegade in 2024. Read more at straitstimes.com. Read more at straitstimes.com.
Downtown BrewFest set May 16 on West Depot Street
ALPS Adult Day Services Greeneville Center will host its 7th annual Downtown BrewFest on Saturday, May 16, in conjunction with the Greeneville Iris Festival.
Maryland becomes 18th state to sanction girls flag football
Maryland has sanctioned girls flag football as a varsity sport, becoming the 18th state to do so. The season begins August 12.
It's Official: Girls' Flag Football is a sanctioned sports for Maryland high schools
Maryland is adding another championship sports to high schools. The Maryland Public Secondary Schools Athletic Association (MPSSAA) officially sanctioned girls'
It's Official: Girls' Flag Football is a sanctioned sports for Maryland high schools
Maryland is adding another championship sports to high schools. The Maryland Public Secondary Schools Athletic Association (MPSSAA) officially sanctioned girls'
14th annual Southwest Colorado Small Business Conference coming to Ignacio in May
The 14th annual Southwest Colorado Small Business Conference promises to supply “practical strategies, fresh ideas, and valuable connections” for attendees from all industries. The conference, which ...
Could your beer have health benefits? Here’s what new research says
A casual beer might come with an unexpected perk. Drinking the occasional pint could provide “substantial levels” of vitamin B6, an essential nutrient that supports brain function, blood health and…
Blue state residents 'fleeing in droves' after ‘insane’ progressive takeover, says top state attorney
Maryland state attorney says he is fleeing the state over what he calls an insane ultra-progressive takeover, sanctuary policies and rising taxes.
Congress keeps holding all-nighters. Lawmakers say it’s a symptom of dysfunction
It's a scenario that is playing out again and again as the House and the Senate fracture and careen from one crisis to the next.
St Mirren v Livingston: Pick of the stats
St Mirren have lost just one of their past 16 Scottish Premiership meetings with Livingston (W7 D8), going down 1-0 away from home in February 2024. Livingston won their first-ever Premiership visit to St Mirren 2-0 in August 2018, but have since failed to win 10 such trips in the competition (D4 L6), losing their past four in a row and failing to score in their latest three. Depending on Kilmarnock's result at Aberdeen, Livingston could be relegated this weekend should they fail to beat St Mirren.
Lucas Parts Ways With SM Entertainment
Lucas, formerly a member of NCT, is leaving SM Entertainment. On April 24, SM Entertainment announced through Weverse that their exclusive contract with Lucas has ended. Read the agency's full statement below: Hello, this is SM Entertainment. We would like to sincerely thank all fans for your continued love and support for Lucas. We hereby inform you that the exclusive contract with Lucas has concluded as of April 24. We will cherish every moment shared, from the early trainee days to the various activities Lucas took part in after his debut, and continue to support him as he begins this new chapter. We kindly ask you to support Lucas’s new journey with encouragement. Thank you. Wishing Lucas all the best on his new journey!
Lucas parts ways with SM Entertainment
Lucas, a former member of NCT, has ended his exclusive contract with SM Entertainment, the agency announced Friday. In a statement released via global fan commu
Prepare for the Reckoning: Lord of Hatred Draws Near
Prepare for the ultimate reckoning against Mephisto. Lord of Hatred burns into Sanctuary next week.
Madrid Presents the Transformation Project of the Former Olympic Aquatic Center Site into a Multifunctional Complex for Sports, Entertainment, and Education
Barsento, the joint venture formed by Live Nation, Oak View Group (OVG), and Atlético de Madrid, has today presented the transformation project of the former Olympic Aquatic Center site alongside the Mayor of Madrid, José Luis Martínez-Almeida. The initiative will breathe new life into the unfinished Aquatic Center building, transforming…
New issue: Mirrorlife | BBC Science Focus Magazine
Mirror life could end all life on Earth. That sounds dramatic, but senior biologists have raised the alarm about experiments happening all around the world. It sounds like something in a Doctor Who plot, but no – mirror life is a real possibility. So why do scientists want to create something that’s potentially apocalyptic? Well, it could also have huge benefits (think back to splitting the atom). The first thing to say, however, is that mirror organisms are still a little way away yet – but only decades, not centuries. So far, scientists have only made mirror molecules, one of life’s building blocks. What for? Life works because its building blocks fit together. Imagine drilling a screw into a piece of wood. The screw cuts a hole with a thread that snugly matches its own. If, for some reason, the Doctor showed up and handed you a mirror version of the screw, its thread would be in reverse. It wouldn’t twist into the hole you’d just made as the threads wouldn’t match. That said, the mirror screw would still work; you’d just have to create a mirror hole for it. Mirror molecules, including DNA, work a bit like that. They follow the same principles as the biology around us, but they’re entirely incompatible with traditional biological functions. In medical terms, this means they’re effectively invisible to your body’s systems. Our biology doesn’t have the tools to recognise these molecules and break them apart. And if someone took these mirror molecules and put them together to make a cell and then an organism… you’d have mirror life. But we don't have any way of breaking it down. If it escaped the lab, we’d just have to hope it didn’t have an appetite.
Google updates Workspace to make AI your new office intern
Google has introduced a host of new automated functions into Workspace, all of which are driven by Workspace Intelligence, its new AI system.
Four receive 2026 L&S Academic Advising Awards
Awards honor faculty and staff who have demonstrated exemplary performance both in terms of their positive impact on students and through distinctive…
Armageddon! Fiasco! Disarray! Is California politics really a total disaster?
Your morning catch-up: A look at California's political dysfunction, plus fraud in the state's hospice industry and more big stories
Trump blasted Obama’s Iran deal. Now he faces similar tradeoffs.
As U.S. envoys pursue peace talks, the president confronts persistent sticking points: sanctions relief, enrichment limits and the risk of empowering Tehran.
Dallas County Republican Party sues over precinct-based voting
The lawsuit is asking that a judge force the county to conduct the May 26 runoff election using precinct-based voting.
The Business Model Podcast: From Idea to Business
Anybody can have a good idea. It’s taking the next step that gives people more trouble. On this Founder Group Chat, we have three founders who have turned
Mechanohealth: Where life science meets physical forces for health innovation
Integrating mechanobiological principles into disease pathogenesis, therapeutic development, and tissue engineering is reshaping our understanding of biological systems and accelerating the advancement of mechanotherapy and mechanohealth. This field reveals how mechanical cues regulate cellular behavior, such as force transmission along integrin-nucleus pathways and collective cell migration, and tissue functions. In doing so, mechanobiology connects fundamental research with clinical applications, from limiting cancer metastasis and fibrosis to promoting bone regeneration and maintaining vascular homeostasis. Building on discussion from the Inaugural International Conference on Mechanobiology (ICM) 2025, integrating mechanobiological research with clinical strategies offers new opportunities to address unmet needs, including personalized anti-fibrotic interventions or precision bone regenerative therapies. At the same time, it supports the broader concept of mechanohealth -- a paradigm focused on preserving the physiological mechanical balance within tissues.
Scientists find a new critical point in supercooled water
X-ray experiments provide further evidence that water exists in two distinct phases
Dario Demonstrates Improved Workplace Function and Productivity Outcomes Through Digital Behavioral Health Program: Real-World Study Published in JMIR Formative Research
/PRNewswire/ -- DarioHealth Corp. (NASDAQ: DRIO) (the "Company", "DarioHealth" or "Dario"), a leader in global digital health, today announced the publication...
Dario Demonstrates Improved Workplace Function and Productivity Outcomes Through Digital Behavioral Health Program: Real-World Study Published in JMIR Formative Research
/PRNewswire/ -- DarioHealth Corp. (NASDAQ: DRIO) (the "Company", "DarioHealth" or "Dario"), a leader in global digital health, today announced the publication...
Inside war-hit Sudan’s only functioning hospital curing tropical diseases
Sudan's health ministry says 37 percent of country's health facilities are out of service as war enters its fourth year.
San Francisco’s mental health board, drug policy under scrutiny this week; Pyramid to get landmark status
This week, the highlights at City Hall include the likely reorganization of a commission overseeing mental health policy, support for drug-free supportive housing, and the possible landmarking of the city’s most visually distinctive building after over 50 years on the skyline. On Monday, the Rules Committee will have a full docket ranging from an ordinance […]
Scientists unveil how heat-loving enzyme could help improve plastic recycling
Cutinases are fungal enzymes that naturally degrade plant cuticles and show promise for recycling plastics. However, they must balance structural rigidity to withstand high temperatures with flexibility required for catalysis. Now, researchers have investigated the structural basis of catalytic activation in a heat-tolerant cutinase, CtCut, from the fungus Chaetomium thermophilum and found that a rigid core supports stability while a flexible lid is associated with catalytic function, offering insights for improving enzymes for plastic recycling.
Multifunctional ligand engineering for pure-blue halide perovskite nanocrystal LEDs
Light: Science & Applications - Passivation with a bifunctional fluorinated ligand stabilizes mixed-halide perovskite nanocrystals, enabling high-color-purity deep-blue emission...
New megafauna looked like spiky, 30-pound hamster
It took 120 years to figure out the forgotten fossil belonged to an extinct giant echidna.
A new force of nature is reshaping the planet, study finds
Human societies didn’t just adapt to the planet—they learned to reshape it. From early fire use to today’s global supply chains, our cultural and social innovations have unlocked extraordinary power to transform Earth and improve human life. But that progress has come with serious costs, including climate change, pollution, and mass extinction. Instead of framing this era—the Anthropocene—as pure crisis, Erle Ellis argues it’s also proof of something hopeful: when people work together, they can drive massive positive change.
Can Claude Write Z80 Assembly Code?
Betteridge’s law applies, but with help and guidance by a human who knows his stuff, [Ready Z80] was able to get a functioning game of Wordle out of the French-named LLM, which is more than w…
$3 million prize goes to duo whose research led to first sickle cell CRISPR therapy
Dr. Swee Lay Thein and Dr. Stuart Orkin won the $3 million Breakthrough Prize in Life Sciences for their work toward a functional cure for the deadly blood disorders sickle cell disease and beta thalassemia.
$3 million prize goes to duo whose research led to first sickle cell CRISPR therapy
Dr. Swee Lay Thein and Dr. Stuart Orkin won the $3 million Breakthrough Prize in Life Sciences for their work toward a functional cure for the deadly blood disorders sickle cell disease and beta thalassemia.
Why Owen Heinecke's return is 'a great benefit,' according to OU coach Brent Venables, teammates
OU head coach Brent Venables and teammates shared their excitement to have redshirt senior linebacker Owen Heinecke returning following a Cleveland County judge’s decision to grant him an injunction for
Neanderthal Babies Were Apparently Built Different and Reached Toddler Size in Only Six Months
A 50,000-year-old infant skeleton reveals our extinct cousins grew up surprisingly fast to survive
Texas Medical Board sanctions three doctors for delayed care that led to the deaths of two pregnant women
The Texas Medical Board has disciplined three doctors ProPublica previously investigated whose patients died after receiving delayed or inappropriate pregnancy care under the state’s strict abortion ban.
Apple to Unveil iOS 27 in June With These New Features Beyond Siri
Apple is expected to unveil iOS 27 during its WWDC 2026 keynote on June 8, and the update should be released in September. Below, we outline some of the new features that are rumored to be coming with iOS 27, beyond the long-awaited more personalized version of Siri. iOS 27 will reportedly support 5G satellite internet connectivity, although this functionality might be limited to the upcoming iPhone 18 Pro models with Apple's next-generation C2 modem.
Super-agers have healthy cognitive function
I just read about people who are called super-agers and how they don't have the memory problems that happen when you get older. Supposedly they have more brain cells. Do you know if that's true? The idea of super-agers is really interesting, and I want to know more.
Childhood Acid Load May Affect Adult Kidney Health
Higher net acid excretion in childhood and adolescence is linked to signs of declining kidney function in adulthood.
Grand Junction students gain real-world business experience through investor pitch event
Young Entrepreneurs Academy participants present months of work to local business leaders for feedback and funding
Grand Junction students gain real-world business experience through investor pitch event
Young Entrepreneurs Academy participants present months of work to local business leaders for feedback and funding
"War is our reality": 4A reveal Metro 2039, a horror FPS inspired by Russia's invasion of Ukraine
Metro 2029 returns the FPS series to the tunnels of Moscow, but this time it's "told from a distinctly Ukrainian perspective."
4 New Apple Intelligence Features Found in Apple Code, Likely in iOS 27
iOS 27 is likely to introduce at least four new Apple Intelligence features that function within system apps, based on backend code discovered by Nicolás Alvarez and confirmed by MacRumors. First up, Apple is expected to lean more heavily into Visual Intelligence in iOS 27, since the company is reportedly developing AI wearable devices that will leverage the feature. Apple is reportedly working on smart glasses, AirPods with cameras, and a wearable AI pin or pendant.
Russia spent extra $130 billion for goods while sanctioned: Latvia
The Latvian analysts said intelligence showed Russia's own forecasts warn it may lose another $136 billion just in trade by 2030 due to the sanctions.
What to know about OU football player Owen Heinecke’s lawsuit against the NCAA, Thursday hearing
An emergency hearing will be held Thursday morning for OU linebacker Owen Heinecke’s preliminary injunction lawsuit against the NCAA for an extra year of eligibility.
UnityPoint Health outsourcing to eliminate hundreds of jobs
UnityPoint Health says it is cutting IT and revenue cycle positions, outsourcing those functions to reduce costs.
Nas.com secures $27M to aid solo entrepreneurs with AI tools
Nuseir Yassin's startup, Nas.com, uses AI tools to help entrepreneurs with a range of business functions like marketing and storefront design.
A crushed fossil revealed a dinosaur that shouldn’t have existed
A badly mangled dinosaur skull, once forgotten in a drawer, turned out to be a rare and important discovery. Reconstructed by a Virginia Tech student, it revealed a new species of early carnivorous dinosaur with unusual features never seen before. The fossil suggests some dinosaur groups were wiped out during the end-Triassic extinction, not just their rivals. It may represent one of the last survivors of an ancient dinosaur lineage.
NEA Outstanding Business Awards handed out; Stafford recognized - Talk Business & Politics
Talk Business & Politics, in conjunction with Arvest Bank, held its annual NEA Outstanding Business Awards event Tuesday (April 14) at the Red Wolf Convention Center in Jonesboro. Winners were...
NEA Outstanding Business Awards handed out; Stafford recognized - Talk Business & Politics
Talk Business & Politics, in conjunction with Arvest Bank, held its annual NEA Outstanding Business Awards event Tuesday (April 14) at the Red Wolf Convention Center in Jonesboro. Winners were...
Building Custom Atomistic Simulation Workflows for Chemistry and Materials Science with NVIDIA ALCHEMI Toolkit
For decades, computational chemistry has faced a tug-of-war between accuracy and speed. Ab initio methods like density functional theory (DFT) provide high fidelity but are computationally expensive…
You can order your own bloodwork now. Interpreting the results is another story
Firms like Function Health and Oura market regular blood tests to people wanting to take their health into their own hands. The process often raises more questions for patients than it can answer.
Wild weekend could bring big changes to race for Governor
"It was a wild weekend in California politics," said Adjunct McGeorge School of Law Professor Chris Micheli.
Fluoride in drinking water has no effect on IQ or brain function, major study shows
The new research is the first to measure community water fluoridation exposure during childhood in the U.S. and any potential impact on cognition up to age 80.
Trump, 79, Raises Fresh Health Concerns After Unbelievable Mix-Up
The president’s feeble reasoning sparked questions about his cognitive function.
Swalwell’s Fall Punctuates Woes of Democrats in California, of All Places
Democrats have struggled to find a candidate for governor who can capture the imagination of voters in one of their most important strongholds.
Erectile dysfunction is more than a sexual issue
Erectile dysfunction is more than a sexual issue.
In the Desert, a ‘Cleaning Station’ for Ants
A unique “choreography” between two ant species suggests a distinctive partnership in which one provides a carwash service to the other.
Ska Brewing sale breathes new life into 30-year-old business
Ska Brewing Co. in Durango has survived more than 30 years of shifting economic landscapes, a pandemic, a multiyear decline for craft breweries on the whole and a recent change of ownership after deca...
Health expert explains link between women's hormones, stress
Functional medicine practitioner Jennifer Gularson highlights how physiological shifts like menopause can trigger significant stress and hormone imbalances.
FULL SHOW: Inside INdiana Business 4/12/26
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New clinic brings at-home health care to La Plata, San Juan counties
HERMOSA – The practice of a doctor traveling to a patient’s home to deliver care – as opposed to the patient traveling to a medical campus or visiting a doctor in an office – is largely bygone. Accord...
Scientists Finally Crack the 100-Million-Year Evolutionary Mystery of Squid and Cuttlefish
Genomic analysis reveals squid and cuttlefish evolved in deep oceans, survived mass extinction in refuges, and later rapidly diversified, following a “long fuse” evolutionary pattern.
Life on Mars? Tiny cells just survived shock waves and toxic soil
Mars may be hostile, but it might not be entirely unlivable. In lab experiments, yeast cells survived simulated Martian shock waves and toxic perchlorate salts—two major environmental threats on the Red Planet. Their secret weapon was forming protective molecular clusters that shield critical cellular functions under stress. Without these defenses, survival plummeted, pointing to a potential universal strategy life could use beyond Earth.
Bridging Oral Health and Integrated Care: A Scientometric Study of Integrated Care for Older People (ICOPE) and Removable Prosthodontics in Older Adults
Population aging has shifted healthcare priorities from disease-centered models towards functional ability and quality of life. The WHO Integrated Care for Older People (ICOPE) framework operati...
Chamber of Commerce Presents Achievement Awards
Event also marked 110th of the chamber’s presence in Oswego [caption id=attachment_10469 align=alignright width=450] Abby Waever and Keara Patterson (in the middle) receive the Community Leadership & Legacy Award, presented to The Alberts Group.[/caption] The Greater Oswego-Fulton Chamber of Commerce (GOFCC) on March 4 hosted its 2026 Annual Meeting, presented by Constellation, at the Lake Ontario Event and Conference Center in Oswego. The event’s theme, Rooted in Community. The meeting celebrated the GOFCC’s 110th anniversary in the Oswego community and 10th anniversary of integration with CenterState CEO. The chamber also unveiled a new logo. “I am proud to say the GOFCC has been a force for business success, growth and opportunity, supporting organizations of every size, connecting neighbors and entrepreneurs and ensuring that every voice in Oswego County is heard,” said GOFCC Executive Director Sara Broadwell. The event featured keynote remarks from Novelis’s Kevin Schutt, vice president, manufacturing and production support at Novelis North America. [caption id=attachment_10454 align=alignright width=450] Maria Hudson of Constellation, holding the award, receives the Nancy L. Premo Woman of Distinction Award.[/caption] The GOFCC recognized the following organizations and individuals with achievement awards: • Oswego County Impact & Excellence Award, presented to Oswego County Office of Mobility Management. This award Honors a small business or nonprofit organization that demonstrates outstanding achievement through innovation, growth and measurable positive impact on Oswego County’s economy or quality of life. • Community Leadership & Legacy Award, presented to The Alberts Group. This award recognizes an individual, business or organization whose long-term leadership, investment or philanthropy has significantly advanced the vitality, resilience and future of Oswego County’s communities. • Nancy L. Premo Woman of Distinction Award, presented to Maria Hudson of Constellation. This award honors a woman in business who has made a meaningful impact on her community, inspired others through her leadership, and exemplified the values of service, integrity and empowerment. This award is presented in tribute to the late Nancy Premo, CenterState CEO’s former vice president of Human Resources.
“AI polls” are fake polls
A few weeks after Donald Trump’s second presidential win, I took the train up from London (where I was living at the time) to Oxford to attend a conference on polls and forecasts of the 2024 election. Most of the attendees were pollsters or academics, but I also watched presentations from Aaru and Electric Twin, two companies that do what is interchangeably called synthetic sampling, silicon sampling, or synthetic audiences. Stripped of startup jargon, that means they use large language models (LLMs) to simulate responses to public opinion polls by having AI agents take on the role of survey respondents. I had already heard of Aaru thanks to some articles with eye-catching headlines like “No people, no problem: AI chatbots predict elections better than humans” in the months leading up to Election Day. The founders were making some big, some might even say far-fetched claims, such as: “within two years, we will simulate the entire globe — from the way crops are grown in Ukraine to how that impacts production of oil in Iraq, trade through the strait of Malacca, and elections for the mayor of Baltimore.” When Semafor asked Aaru’s cofounders — Cameron Fink and Ned Koh — about my boss, they said “we respect all those who came before us.” Nate (as he so often does) shared his thoughts on Twitter: Fink and Koh were relatively good-natured about this back-and-forth when we spoke at Oxford. They even offered to mail me one of the t-shirts featuring Nate’s quote they apparently had made. I never took them up on the offer, which I now somewhat regret. These synthetic sampling companies fell off my radar for a while, but they do still exist. In fact, Aaru recently received a $1 billion valuation. Is what they’re doing anywhere close to the most important frontier in AI development? Not by a longshot, especially when Anthropic just developed a model so adept at exploiting software vulnerabilities that it’s only being released to 40 companies. Still, silicon sampling is increasingly finding its way into public polling. Axios reported in March that “a majority of people trust their own doctors and nurses” based on findings from Aaru — without mentioning that the “people” in that sentence were actually LLMs. Around the same time, the Public Sentiment Institute “boosted” their online sample of 373 real survey respondents with 114 AI agents.1 (Spoiler alert: even the co-founder of Electric Twin doesn’t think that’s a particularly defensible approach.) Polling companies like Qualtrics and Ipsos are also developing synthetic data panels. So, what should we make of these … “polls”? Let’s get one thing out of the way: whatever they are, they’re not polls in the way that term is usually defined. Subscribe You can’t replace polls with AI On one hand, using LLMs to essentially make up fake survey respondents sort of sounds like the dumbest idea ever, one that will at best imperfectly replicate real polls while introducing all sorts of biases. On the other hand, with LLMs improving at a remarkable, perhaps even alarming rate, maybe that means I’m a dinosaur at the ripe old age of 24 because I still want to rely on polls that talk to actual people. I’m not going to argue that synthetic samples are completely useless. In fact, as I’ll return to later, there is evidence that some techniques can replicate topline survey results quickly and cheaply. But the marketing from certain companies can be slightly optimistic. “No traditional poll will exist by the time the next general election occurs,” said Fink in 2024. We’re just 206 days away from the midterms, and based on the fact that I still have to collect a bunch of polls every day, I’d say he should have run that prediction by a sample of AI agents before the interview.2 To see why synthetic samples can’t replace polls, here’s a quick primer on how they work. The simplest version of these models involves taking a LLM (like ChatGPT or Claude), giving it a demographic profile (e.g., a white, college-educated woman who lives in Utah and makes $70k a year), and then asking it to respond to a survey question. You repeat that process a few thousand times using different demographic profiles and end up with a sample of synthetic survey responses. The actual models used by private companies are more sophisticated than this, usually because they incorporate more hypothesized demographic characteristics for each agent and provide them with extra information. Aaru, for example, feeds agents a diet of news and information they’d be likely to consume, while Electric Twin incorporates their customers’ proprietary data about the audience they’re trying to replicate. The way Ben Warner, the co-founder of Electric Twin, explained it to me was “we have a large amount of data on […] for instance, 5,000 people. Can we make an accurate prediction of how they would respond to another question?” Still, it should be obvious why synthetic samples can’t replace polls. Polling is fundamentally a data collection process. We might use surveys to make predictions by feeding them into election forecasts, but the main purpose of a poll isn’t prediction, it’s gathering new data about what people think and how they feel. Silicon sampling, on the other hand, produces no new data. It’s simply a model: you input LLM training data, demographic prompts, and a bunch of other information, and it spits out a prediction for what a poll would say. We love models here, but models aren’t polls. That difference is an important philosophical sticking point for most pollsters I talk to. “I think politics should stay away from [synthetic sampling], because we’re trying to […] represent the voice of the people,” said Natalie Jackson, a vice president at GQR Insights. Democratic pollster John Hagner told me: “I think I’m just incredibly skeptical of this idea. I don’t think it’s research. At that point, you’re asking the machine to tell you what you already believe.” Hagner has seen some presentations of early synthetic sampling experiments, but so far, “if it’s being used in a campaign, people are keeping it incredibly quiet.”3 But Eli, I hear you saying, aren’t polls themselves increasingly governed by modeling decisions? Indeed they are: pollsters’ choices on which sampling method to use, how to define their likely voter models, and how to weight their samples can and do lead to dramatic differences in the results they publish. Aaru even referenced these limitations in the methodology statement included with that maternal mortality “poll” — although I’m using the term “methodology statement” loosely here, because it doesn’t really explain how the model works at all. We can ignore the (frankly preposterous) implication that synthetic sampling isn’t subject to a separate set of biases. The important point is that there’s still a meaningful difference between using weighting and other statistical techniques on actual polling data and using a model to predict what a poll would say. The latter is far closer to election forecasts or techniques like MRP — potentially useful models, but not a replacement for polls.4 To be fair, other synthetic sampling companies are perfectly happy with the distinction between polls and models. Warner compared polling and synthetic sampling to different tools in a toolbox. “The mistake I think we make is we think that these new tools should either work in exactly the same way or somehow replace these old tools,” he said. “Rather than thinking of it as, okay, so we’ve always had the hammer, we’ve always had the screwdriver, now we’ve got a saw. But don’t use a saw to try [to] do the job of a hammer.” A quick comment from Nate Eli didn’t ask me for a comment — rather rude of him, don’t you think? But since I’m editing this story, I figured I’d add a few quick thoughts rather than putting words in his mouth. Beyond the frequently misleading marketing, what bothers me about the AI “poll” hype is that as AI tools make statistical inference cheaper and/or better (note that these are not synonyms) that actually increases the comparative value of collecting original data. You might be able to train a model to make a reasonable estimate of what some hard-to-reach poll respondent would say — say, a young Black man who voted for Trump. (Such a person checks a number of boxes for a voter who is usually hard to reach in surveys.) Indeed, this is closely related to what models like the Silver Bulletin forecast already do. They essentially smooth out the kinks in noisy survey data by making inferences based on past voting patterns or national polls or surveys of other states. But you don’t actually know what these voters think unless you’re reaching them directly. If there’s a shift in opinion among this subgroup, you’re not going to detect it. So if I were running a campaign, I’d invest more in going the extra mile to find a representative sample of those voters. And then I’d hire some smart quants — or Claude? — to figure out the implications for campaign strategy based on proprietary data that my competitors didn’t have access to. -Nate Silver Are these models any good? If synthetic surveys are just a new type of model, the next obvious question is whether the models are at least accurate. The answer very much depends on who you ask. On one end of the spectrum, you have the maximalist argument that synthetic sampling is more accurate than actual polls. “It’s an incredibly challenging problem to go to someone and say ‘hey, we’re going to be more accurate at predicting human behavior than you, even when you talk to your customers directly’,” Koh recently told CNBC. In his view, synthetic sampling isn’t a saw to polling’s hammer, it’s “magic.” There’s certainly evidence that synthetic samples can replicate certain survey toplines. But if Aaru does have any examples of their approach outperforming the polls, they’re keeping those to themselves.5 Aaru’s 2024 election model, for example, had Kamala Harris leading in Michigan, Nevada, Pennsylvania, and Wisconsin on November 4th. And although they’ve since taken down their forecast page, they gave Harris a 50.5 percent chance of winning the race on November 2nd.6 After the election, Fink told Semafor he was happy enough with those results because they were “within margin of error,” a term that is completely meaningless when applied to a “sample” of AI agents. And of course, Aaru says their models have improved since 2024, so supposedly now they’d be more accurate than the polls? Still, their stronger argument is on cost: “We are significantly faster and cheaper than traditional polling, and still more accurate,” said Fink. The first two claims are undeniably true, but the third brings us to the opposite end of the spectrum. Both Jackson and Hagner are skeptical that these models are reliable for anything beyond replicating common survey toplines. “I just […] don’t think the machines are what we want when we’re looking for nuanced views. My example on this is people in Arizona and Nevada in 2024 who voted for Trump and voted for expanding abortion in their states on ballot initiatives,” said Jackson. Hagner identified another issue. Maybe the synthetic respondents, like sycophantic LLMs, are inhuman in one important way: they’re too nice. “The reports that have come through at the meetings that I’ve been at are that the early experiments on this, they cannot get respondents to be as racist or sexist or, frankly, as negative as human respondents,” he said. Academic research mostly agrees on this point. While there are some papers that show promising results when using LLMs to replicate polling data, most show that LLMs suffer from various quirks like producing too few “don’t know” responses and can seriously overpredict the favorability of politicians like Donald Trump and Kamala Harris. They also seem to struggle with too little variation between demographic subgroups, so the difference in predicted opinion between Democrats and Republicans, for example, is too small. When I asked Warner about these studies, his response to these papers was that just because academics can’t get synthetic sampling to work doesn’t mean that the technique doesn’t work in general. “Actually, the argument is, okay, yours does not [work]. That does not mean […] for this complex set of machinery, which uses a lot of investment, a lot of time, a lot of money, you can’t get it to work.” Cards on the table, I’m somewhat sympathetic to this argument because academics aren’t exactly great at making election forecasts. Usually, the people with skin in the game are the most accurate. Warner’s argument is that the approach Electric Twin takes — which includes, for example, making multiple predictions for each synthetic respondent using different models and prompts and subsequently averaging those to get a final prediction in a sort of ensemble forecast — produces better results than the simpler academic models. Warner shared a comparison between his method and the method from a recent academic paper with me, and Electric Twin was indeed able to get more accurate replication. But even still, he acknowledged that synthetic sampling “is not a crystal ball.” “If you asked me, do I think using other data sources will be more accurate than asking somebody who they will vote for, I would probably say no. But if you asked me ‘would your system be useful for our turnout modeling today?’ I would say yes.” For better or worse, it looks like the method is already getting more popular in the market research world. Most of the clients Aaru touts these days are businesses like EY and McDonald’s. And AI will probably begin to pop up in other parts of the political polling process. Pollsters are already using it to code open-ended survey responses, and some firms, like YouGov, are testing using LLMs to ask survey respondents questions. More worryingly, one danger to actual polls is that AI agents can be used to infiltrate online surveys. Most online polls use various checks to prevent that from happening, but there’s conflicting evidence on how effective those filters are and how prevalent AI agents currently are in online panels. If those agents ever become impossible to detect, it might spell the end of online polling, but the solution isn’t to replace all of your respondents with ChatGPT. Silver Bulletin is a reader-supported publication. To receive new posts and support our work, consider becoming a subscriber. Subscribe 1 That particular poll obviously doesn’t meet Silver Bulletin standards for aggregation. But we exclude all Public Sentiment Institute polls from our averages because we classify them as an amateur polling firm. 2 You could argue that Fink meant the next presidential election, but (a) I’m also confident we’ll still have real polls in 2028 and (b) in that case he should have asked an LLM to define “general election.” 3 Quick caveat: that’s reporting from a Democratic pollster. It’s possible that Republicans are more willing to use AI in political campaigns. 4 Indeed, Silver Bulletin does not include “polls” produced by MRP in our forecasts or averages, and we think it’s extremely misleading when their practitioners describe them in a way that suggests original data had been collected among a large number of states or Congressional districts. 5 A recent report from Aaru and EY did show two examples of a synthetic estimate being closer than a survey to a real-world benchmark — but I’d take those findings with a grain of salt because the report reads more like an ad and didn’t involve any sort of prediction being made ahead of time. 6 For comparison, our odds for Harris on the same day were 48.2 percent.
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Viewpoint: FP10 should remain open, excellent and secure
Europe is right to worry about research security. Foreign interference is real. So is the misuse of sensitive knowledge. Universities working in sensitive areas such as AI, quantum, semiconductors and advanced materials cannot afford to ignore the geopolitical environment around them.But Europe is in danger of drawing the wrong conclusion, one that would increase, not reduce, its strategic vulnerabilities.If the EU applies an “EU preference” logic to the next Framework Programme for research and innovation (FP10), it will weaken one of its greatest strategic assets: a research system built on openness, excellence and international collaboration. In the name of security, Europe could end up advancing science more slowly, innovating less effectively and making itself less attractive to global talent and partners in advanced science and technology.That would be a serious mistake.The EU preference included in Article 10 of the proposed European Competitiveness Fund may make sense in some industrial or deployment contexts, but is far harder to justify when applied to collaborative research in advanced science and technology, where excellence and global connectivity are crucial. Research is not procurement. It does not thrive when isolated. It advances through access to the best ideas, the best people, the best facilities and the best data, wherever they are found. This is why FP10 should not simply absorb industrial policy logic by default. Doing so would risk importing instruments that are ill-suited to research and that ultimately increase vulnerability rather than resilience.For universities of science and technology, the issue is especially acute. These institutions sit at the frontier of knowledge and technology creation in the very fields Europe sees as critical for its future competitiveness and resilience. They know better than most that security risks are real. But they also know that openness and security are not opposites. In practice, they have to be made to work together. Research security is not about closing doors. It is about building resilience through collective responsibility, trust, proportionate safeguards and better governance. That is a fundamentally different approach from default restriction.The risks of non-collaborationThe real danger in the current debate is that Europe talks too much about the risks of collaboration and not enough about the risks of non-collaboration. Those risks are strategic too. Cut researchers off from international networks and Europe loses access to knowledge, data, infrastructures and talent. Slow down global collaboration in critical technologies and Europe slows down its own progress on cutting-edge science. Make participation rules unpredictable and Europe weakens its attractiveness to researchers and investors alike.In other words, over-restricting collaboration will create strategic vulnerabilities, particularly in advanced science and technologies.This point is often underestimated in policy discussions that frame openness mainly as a value to be defended. Europe’s scientific strength, technological development and long-term competitiveness depend on remaining connected to the best research ecosystems in the world. For a continent that wants to accelerate deep tech, strengthen industrial capacity and reduce strategic dependencies, weakening the excellence base would be self-defeating. That does not mean ignoring risk. Quite the opposite. Universities are already strengthening due diligence, internal governance, awareness-raising, screening procedures and compliance support. Across Europe, institutions are working to manage risks linked to foreign interference, sanctions, export controls and the misuse of research. The right response is not complacency. It is better risk management. But that means targeted, evidence-based and proportionate measures, not blunt top-down restrictions with wide spillover effects. In the daily reality of universities, openness and restriction often coexist. The real challenge is how to apply safeguards without sliding into securitisation that damages academic freedom, open science and international cooperation. Restrict partners, not nationsMore restrictive treatment of collaborators from European Economic Area members Iceland, Liechtenstein and Norway, or from Switzerland and the UK, is strategically very difficult to justify. These are deeply embedded partners in Europe’s research and innovation ecosystem. Beyond that, Europe should still resist default exclusion and instead rely on case-by-case assessment. The relevant question is not nationality in the abstract. It is the actual risk profile of a collaboration: the institution, the affiliations, the field, the knowledge involved, the intended use and the safeguards available. Screening should focus on institutions and affiliations rather than nationality alone. Related articlesParliament ‘misreads’ link between Horizon Europe and ECF, Commission official saysFrustration grows at governance gap in next Horizon EuropeIf EU preference logic is imported into research without careful calibration, the likely result is a chilling effect. Researchers may step back from legitimate and beneficial collaboration, even where risks are manageable. International partners may see Europe as less predictable. And Europe may end up undermining the very excellence base it needs to compete, scale up and lead in strategic technologies, thereby increasing its dependence on others.FP10 should do the opposite. It should remain open by default, with restrictions used only exceptionally, and then on the basis of clear evidence. It should integrate research security into open science and research integrity frameworks, not set them against each other. And it should recognise that academic freedom, scientific excellence and responsible international collaboration are not obstacles to Europe’s security, they are part of it. Europe needs stronger tools to protect itself. But it also needs the discipline to avoid measures that would weaken it and increase its strategic vulnerabilities in the process. In FP10, that means staying open, excellent and secure.Louise Drogoul is senior advisor for innovation and sustainability at the Cesaer university association.
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