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Man in custody after report of assault with deadly weapon at Venice health center
Law enforcement officers responded Tuesday to a report of an assault with a deadly weapon outside a health center in Venice Officers, including SWAT team members in at least one armored vehicle, were at the Chuck Lorre Rose Avenue Wellness Center after the report of a suspect with gun. A standoff ensued before the man walked along the outside of…
Democrats’ long-shot bid to flip Alaska’s Senate seat
Democrats are hoping for an upset in Alaska’s Senate race. U.S. Rep. Mary Peltola, a Democrat, is trying to unseat Republican incumbent Sen. Dan Sullivan. We discuss the major issues at play, plus why Republicans are backing an effort to repeal Alaska’s ranked-choice voting system.This episode: voting correspondent Miles Parks, senior political editor and correspondent Domenico Montanaro, and Alaska Public Media Washington correspondent Liz Ruskin.This podcast was produced by Casey Morell and Bria Suggs, and edited by Rachel Baye.Our executive producer is Muthoni Muturi.Listen to every episode of the NPR Politics Podcast sponsor-free, unlock access to bonus episodes with more from the NPR Politics team, and support public media when you sign up for The NPR Politics Podcast+ at plus.npr.org/politics.
Blog explains why context matters in discussions on health care spending
An AHA blog published March 24 responds to a recent KFF brief on the role of hospital care in recent health care spending growth.
G7 Entertainment Marketing Launches Wild by G7 to Help Destinations Turn Culture Into Travel Demand
New Venture Responds to Surging Demand for Experience-Driven Travel by Helping Destinations Create Cultural Moments that Drive Visitation, Economic Impact, and Brand Loyalty Wild by G7 is producing the Rendezvous Music Festival The Head and the Heart band performed at a past Rendezvous Music Festival in Jackson, Wyoming Wild by G7 Sizzle NASHVILLE, Tenn. and JACKSON, Wyo., March 24, 2026 (GLOBE NEWSWIRE) -- G7 Entertainment Marketing, the experiential and talent booking agency behind campaigns f
Segment: Financing Action on Extreme Heat and Maternal and Newborn Health: The Way Forward
The segment “Financing Action on Extreme Heat and Maternal and Newborn Health: The Way Forward” will examine how innovative and better-aligned financing approaches can respond to these growing risks. Discussions will highlight country experiences in mobilizing domestic resources, opportunities to unlock and scale climate finance, and the role of heat-smart innovations in building resilient health systems. Particular attention will be given to low- and middle-income countries, where exposure and vulnerability remain highest, and where integrated solutions can deliver the greatest impact.
Henderson County launches crisis response program for behavioral health emergencies
In Henderson County, officials say a new program is already working to respond when someone is in crisis, often through a 911 call.
Bird‑like robots promise greater flexibility and control than drones
A bird banking in a crosswind doesn't rely on spinning blades. Its wings flex, twist and respond instantly to its environment. Engineers at Rutgers University have taken a major step toward building bird-like ...
Politics, protests and popular culture: The University of Minnesota community responds to ICE impact through memes and music
Outside Coffman Union on March 3, The University of Minnesota’s Students for a Democratic Society protested Immigration and Customs Enforcement’s presence in Minnesota and on campus, despite reports that Operation...
Crews responding to fire burning behind an Upstate business
Multiple fire departments responded to a fire behind the Tractor Supply Co. in Mauldin, SC.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Chappell Roan reacts to claims her security made Jude Law's 11-year-old daughter cry: 'I do not hate children'
Chappell Roan has responded to claims that her security guard made Jude Law's 11-year-old daughter cry after she got excited when she spotted the singer in a hotel: 'I do not hate children— that is crazy.'
Oil prices face new pressure as US and Iran trade threats
Trump said the US would attack Iran's power plants if it didn't reopen the Strait of Hormuz in 48 hours. Iran responded on Sunday with is own threats.
Crimson Desert admits it used generative AI for "early-stage iteration" and apologises AI images were not replaced before release
Crimson Desert developer Pearl Abyss has responded to claims its latest game used AI to generate images, admitting "2D …
‘Trump should keep his reckless mouth shut’: Jeffries responds to Trump calling Democrats America’s ‘greatest enemy’
Readers Respond to Health Insurance Chaos for Providence Customers
“Only other questions I have is who is starting the class action and where can I sign up?”
Maine progressive Senate candidate Graham Platner responds to Gov. Janet Mills’ attack on his online past
'Saturday Night Live UK' aims to take a comedy hit across the pond. The first verdicts are in
A British version of “Saturday Night Live” has debuted to largely positive reviews. The first episode of “SNL UK” was hosted by Tina Fey, a veteran of the American show, and stuck closely in...
\'Saturday Night Live UK\' aims to take a comedy hit across the pond. The first verdicts are in
A British version of “Saturday Night Live” has debuted to largely positive reviews. The first episode of “SNL UK” was hosted by Tina Fey, a veteran of the American show,
'Saturday Night Live UK' aims to take a comedy hit across the pond. The first verdicts are in
A British version of “Saturday Night Live” has debuted to largely positive reviews.
'Saturday Night Live UK' aims to take a comedy hit across the pond. The first verdicts are in
A British version of “Saturday Night Live” has debuted to largely positive reviews.
Politics: Iowa Senate majority leader outlines plans for coming weeks
Second funnel week concluded in the Iowa Legislature, meaning that lawmakers’ focus can return to funding, appropriations and other types of specific bills that don’t respond to the Legislature’s self-imposed
Trump responds to Robert Mueller's death. 'I'm glad.'
President Donald Trump has responded to the death of former special counsel Robert Mueller on Saturday, March 21. Here's what he said.
Downtown Chico business owner voices concerns over street closures for events
A DOWNTOWN CHICO MERCHANT IS EXPRESSING CONCERN OVER THE IMPACT OF STREET CLOSURES FOR EVENTS -- ON THEIR BUSINESS. ACTION NEWS NOW REPORTER BELLA BARBOSA REPORTS FROM DOWNTOWN CHICO { "@context": "https://schema.org", "@type": "VideoObject", "name": "Downtown Road Closure Dilemma", "description": "A DOWNTOWN CHICO MERCHANT IS EXPRESSING CONCERN OVER THE IMPACT OF STREET CLOSURES FOR EVENTS -- ON THEIR BUSINESS. ACTION NEWS NOW REPORTER BELLA BARBOSA REPORTS FROM DOWNTOWN CHICO", "thumbnailUrl": "https://bloximages.newyork1.vip.townnews.com/actionnewsnow.com/content/tncms/assets/v3/editorial/c/47/c47e26d6-03c3-5f35-bf49-37925ab603d7/69bdedc4eb57d.image.jpg", "uploadDate": "2026-03-20T17:45:00-07:00", "contentUrl": "https://cdn.field59.com/KHSL/1774053903-6e1ef36dd09fbebf020833aee86b60da3b3cca3f_fl9-720p.mp4" } CHICO, Calif. - A downtown Chico business owner is voicing concerns about the impact of street closures for events on local shops. Leann Powell, owner of The Peddler’s Closet, expressed concern about events closing down streets downtown and bringing in food trucks and other shops’ products that directly compete with the brick-and-mortar stores in downtown Chico.Powell said an upcoming event held on a Saturday has brought up concerns for her and other business owners downtown, due to it being a busy day for businesses. "We're already struggling, and then to bring in more businesses on top of our businesses and shut our streets down is absolutely devastating," said Powell.Powell noted a decline in business during events like the Thursday Night Market, where street closures allow outside vendors to set up shop. She shared that while organizers for these types of events often offer booths to local businesses, it does not alleviate the burden."I don't really feel like that's a solution because you're bringing in other businesses, you're shutting the streets down. Yes, we can go down and set up a space, but then you've gotta pay somebody to run that space, plus run your own business for the day, and it's really not, it's really not helpful for us," said Powell.Applying for a street closure permit in Chico involves approval from the Public Works Department, the Chief of Police, and the Fire Chief. Permits can be denied only under a handful of circumstances, such as interference with first responders, previously scheduled construction, or existing permits for the same space.Mayor Kasey Reynolds addressed the issue, saying the city council has tasked staff with reviewing the municipal code for street closure permits with the goal of finding ways to minimize negative impacts on local businesses during events.Reynolds mentioned that any recommended changes might require further direction from the city council, depending on the extent of any changes recommended. googletag.cmd.push(function() { googletag.display('ad-1514992'); });
Police responding to business explosion in Carroll County
According to a spokesperson for the Carroll County Sheriff’s Department, the explosion occurred Friday afternoon at the address of Catoctin Mountain Growers.
Microsoft confirms a major Windows 11 update with faster Explorer, reduced Copilot, and more
Windows 11 in 2026 will bring taskbar fixes, better performance, lower RAM usage, and fewer updates as Microsoft responds to user feedback.
Crimson Desert developers "doing our utmost" to respond to its various launch issues, as game still passes huge one-day sales milestone
Crimson Desert - the ambitious single player RPG spin-off from Pearl Abyss - has sold through 2m copies following its release.
New dispute emerges around Subnautica 2’s early access release
Lawyers for the ousted—and now partially reinstated—leadership team of Unknown Worlds, the studio behind Subnautica 2, are crying foul over news that the game will be released into early access in May. The release announcement earlier this week was made improperly, potentially “damaging the game and sowing additional confusion among the Subnautica community,” the lawyers said in a letter sent on Tuesday to Vice Chancellor Lori Will of Delaware’s Court of Chancery. In their letter, the lawyers also floated the idea of asking Will to find Krafton in contempt of the court’s ruling. The letter was sent just one day after Will’s bombshell ruling that publisher Krafton had breached its contract with Unknown Worlds’ executive team, when it fired them last June. The new issue isn’t necessarily the May early access timeframe, but how the news was announced. The letter and Krafton’s response have not been previously reported. A quick recap of prior events: Subnautica 2 is an unreleased, underwater survival adventure and the most-wishlisted game on Steam. Last year, longtime Unknown Worlds CEO Ted Gill, along with studio co-founders Charlie Cleveland and Max McGuire, were fired by Krafton. They swiftly sued, saying the publisher had terminated them to avoid paying out up to $250 million in potential performance-based bonuses. The studio leaders had hoped to earn that with an early access release of the game, which Krafton had blocked. The publisher argued in court that Subnautica 2 wasn’t ready, which the ousted execs disputed. On Monday, Will ruled that Krafton had violated its contract, firing the execs to avoid the performance payouts, and that it had to reinstate Gill and give him full authority over any early access release for Subnautica 2. On Tuesday, IGN reported on a new memo issued that day to Unknown Worlds staff by Steve Papoutsis, the executive Krafton had put in charge of Unknown Worlds after the 2025 firings. In the note, Papoutsis said that Subnautica 2 had passed a key development milestone “last week” and that he and Krafton had determined the game “is ready for Early Access release in May.” This news appeared to catch the lawyers for Gill, Cleveland and McGuire by surprise. On Tuesday night, they sent a letter to Will expressing “serious concerns” about whether it would be possible to forge an agreement with Krafton consistent with the judge’s order. Papoutsis’ memo was a problem, they wrote. He didn’t have the authority to declare anything about Subnautica 2’s release. As of 9am ET on Monday, March 16, the effective date of Will’s order, Papoutsis wasn’t CEO of Unknown Worlds. Gill was. And, per Will’s order, only Gill could make Subnautica 2 release decisions. They continued: Krafton self-servingly announced the launch without any regard to its impact on the game, the team, or the community—let alone this Court’s Opinion. Announcing the release of a game is momentous, and it is typically accompanied by significant marketing activity, fanfare, and community coordination. And most importantly, the announcement is carefully designed to maximize excitement for the game. That entire process was supposed to be driven by Mr. Gill. However, in defiance of the Court’s Opinion, Krafton has now taken that away, further damaging the game and sowing additional confusion among the Subnautica community. The lawyers speculated that Krafton had “intentionally leaked” Papoutsis’ memo and then issued an official statement to confirm the leak. Game File is a reader-supported publication. My reporting is only possible through support from readers like you. To support my work, consider becoming a free or paid subscriber. Subscribe On Wednesday, lawyers for Krafton defended their client in their own letter to vice chancellor Will, saying nothing they did violated her order nor showed contempt: Papoutsis’s message was simply celebrating the UW employees’ efforts toward a past event: Krafton’s pre-Opinion determination that Subnautica 2 was ready for Early Access release. There was nothing improper about conveying the results of the milestone review or thanking the development team for their dedication and talent. They added that Gill could still make his own call about Subnautica 2’s release: In his role as CEO, Gill will be able to assess independently his views on the state of Subnautica 2 and the appropriate release schedule; nothing in Papoutsis’s message alters Gill’s authority or discretion. Vice chancellor Will has not responded to the letters and doesn’t necessarily have to. Both parties were previously ordered by Will to confer this week and submit a proposed judgment consistent with her ruling. The letter from Gill’s attorney’s this week doesn’t indicate whether he would or would not support a May release for Subnautica 2. But it could limit his options. And, if Gill’s lawyers are right, the lack of marketing fanfare around the leak of the May date could dull the launch of the game. Any harm to Subnautica 2’s launch is an extra sensitive issue given the context of the legal dispute: millions of dollars of payouts are on the line, tethered to the scale of the game’s initial performance. In her ruling on Monday, Will noted that there was obvious “bad blood” between Gill’s side and Krafton but that the two would need to work together: “They can—and must—act in good faith to navigate their remaining contractual relationship.” Item 2: A new kind of couch co-op game A highlight of GDC each year is the Alt.Ctrl showcase that features games played with extremely experimental controllers. Perusing this year’s offerings last Friday, I found a game controlled with giant scissors, another with big toothbrushes and one that amounted to dumpster diving. My favorite was Pivot, a co-op game about collectively maneuvering a couch. It was developed by students at the University of Utah’s masters of arts and engineering games program. Players lift and tilt the physical couch in order to control the position of a virtual one. That virtual one is moving through an obstacle course on-screen, while being pursued by a giant skull. Developer Nishant Verma told me at GDC that the couch is made of styrofoam (this became more evident as I watched!) and that the name was a riff on an episode of the sitcom Friends. Item 3: In brief… 🚫 Ubisoft is laying off more than 100 workers at its Red Storm studio, as the North Carolina location known for decades for its Tom Clancy games, ceases in-house game development, VGC reports. 👀 On Monday, Nvidia’s revealed its DLSS 5 AI-driven graphics technology that purports to improve game graphics… and it has been roasted about it by the media and the online gaming public for the remainder of the week. The tech changed the faces of characters in footage from Resident Evil Requiem, Hogwarts Legacy and EA Sports FC, drawing accusations of giving carefully art-directed games the generic look of AI “slop.” Nvidia CEO Jensen Huang had said on Monday that “DLSS 5 is the GPT moment for graphics—blending handcrafted rendering with generative AI to deliver a dramatic leap in visual realism while preserving the control artists need for creative expression.” By mid-week, Huang was telling Tom’s Hardware that the new tech’s critics were “completely wrong” because game-makers could still “fine-tune the generative AI” to suit their game’s aesthetics.
German Health Minister Nina Warken and WHO Hub in Berlin highlight 2025 achievements
Germany’s Federal Minister of Health, Nina Warken, visited the WHO Hub for Pandemic and Epidemic Intelligence in Berlin today to review progress and launch its 2025 Annual Report. The report highlights advances in using artificial intelligence, data science and pathogen genomics to strengthen global preparedness for future pandemics.In 2025, the WHO Hub in Berlin worked with more than 160 Member States and over 190 partners to help countries and organizations develop new systems and tools to detect and understand new public health threats as quickly as possible, whenever and wherever they occur.BMG to confirm whether they wish to contribute a quote. “Detecting outbreaks early is one of the most effective ways to save lives and prevent epidemics from becoming global crises,” said Federal Minister of Health Nina Warken. “Germany is proud to host and support the WHO Hub for Pandemic and Epidemic Intelligence. Its work strengthens our safety at home and helps protect people worldwide.”Artificial intelligence is increasingly transforming the detection of outbreaks. In 2025, the Hub launched an upgraded version of the Epidemic Intelligence from Open Sources (EIOS) system, which uses enhanced AI functions to scan global online information in real time and help experts quickly identify unusual health events. The system is now used by 120 countries.To better anticipate health threats, countries need information beyond traditional health data. The Hub supports countries in implementing Collaborative Surveillance, which integrates data on climate, animals, travel, and population movement to provide a more comprehensive and real-time understanding of health threats.The Hub also expanded global access to pathogen genomics, which helps scientists detect new pathogens, such as viruses and bacteria, understand how they spread and how dangerous they may become. Through the International Pathogen Surveillance Network (IPSN), the WHO Hub in Berlin worked with 309 partners in 101 countries to expand access to these technologies.“We are in a new era of global health threats, and we need new tools to face tomorrow’s challenges,” said Dr Chikwe Ihekweazu, Executive Director of the WHO Health Emergencies Programme. “The WHO Hub in Berlin helps countries use data and technology more effectively so they can identify risks earlier and respond faster. No country can address these threats alone. Strong cooperation remains our best defence.”“Berlin offers an ideal environment for our work. We collaborate closely with world-leading institutions such as the Robert Koch Institute and the Charité Center for Global Health,” said Dr Oliver Morgan, Head of the WHO Hub for Pandemic and Epidemic Intelligence. “Germany has supported the WHO Hub since its establishment, and we are pleased to welcome Federal Minister Nina Warken to the Hub today. This strong partnership helps us advance innovation in pandemic and epidemic intelligence and better support countries to prepare for future health threats.”The Hub is expanding the use of advanced analytics and mathematical modelling to forecast how outbreaks may develop and to assess which response measures are most effective. Through its Collaboratory, the Hub connects modelers and analysts with governments to ensure their work addresses real public health needs. In 2025, the community grew to 1300 members from 50 countries and 200 institutions. An AI-powered pandemic simulator, currently in the prototyping phase, will help decision-makers compare outbreak scenarios and help identify effective disease control measures.
Lebanon: Israel must halt attacks on healthcare workers, medical facilities and first responders
Responding to the killings and injuries of dozens of healthcare workers and first responders in Lebanon since 2 March 2026, amid escalating attacks by the Israeli military and its allegations – without providing evidence – that ambulances and healthcare sites are being used for military activities and may be targeted, Kristine Beckerle, Deputy Regional Director for the Middle East and North Africa at Amnesty International, said: “Israel is deploying the same deadly playbook it used in 2024 in Lebanon to kill dozens […]
Watch: Affordability Plagues Health Care in Its Shift From Nonprofit to Profit Machine
On “What the Health? From KFF Health News,” distributed by WAMU, chief Washington correspondent and host Julie Rovner sat down with Drew Altman, president and CEO of KFF, to talk about the likelihood of a national health care debate.
Rats, gnats and Yik Yak. Queens University responds to dining health concerns
The university received a lackluster health inspection in January and an improved one in February before other student concerns emerged.
Researchers surveyed by STAT detail the scientific and personal toll of grant cuts: ‘This can't be how it ends’
STAT interviews with 30 respondents brought the unmistakably human impacts of federal science policy into sharp focus. Here are three of those stories.
Issues & Ale: It's Just Politics
Join Michigan Public's Political Director Zoe Clark, Senior Capitol Correspondent Rick Pluta, and their FAQ Squad panelists as they give you the facts of the upcoming election cycle!
Why people are making fun of Nvidia’s DLSS 5 on social media
Video game fans are responding with criticism and comedy to Nvidia's latest version of its AI technology that boost performance and graphics.
What everyone gets wrong about the science of lip-reading
Letter: Jill Jones responds to the news that royals and celebrities have been warned to watch their words when out and about
Platner responds to Mills’ ad highlighting past comments
The ad quoted Platner writing that if women want to avoid rape they should make sure they don’t get so altered that “they wind up having sex with someone they don’t mean to” and that they should “act like an adult.”
SoFi Responds to Inaccurate Short Seller Report
SoFi Technologies, Inc. (NASDAQ: SOFI), the one-stop shop for digital financial services, today issued the following statement: The claims made in the Muddy ...
The race for a safe Democratic House seat offers clues about the party’s future
It’s Primary Day in Illinois, where 15 Democrats, spanning three generations, are vying to succeed longtime Congresswoman Jan Schakowsky in the state's 9th Congressional District. We discuss what the race tells us about the future of the Democratic Party.This episode: senior White House correspondent Tamara Keith, political reporter Elena Moore, and senior political editor and correspondent Domenico Montanaro.This podcast was produced by Casey Morell and Bria Suggs, and edited by Rachel Baye. Our executive producer is Muthoni Muturi.Listen to every episode of the NPR Politics Podcast sponsor-free, unlock access to bonus episodes with more from the NPR Politics team, and support public media when you sign up for The NPR Politics Podcast+ at plus.npr.org/politics.
Trump says NATO's refusal to help on Iran is 'very foolish mistake'
Trump called on nations to help police the Strait of Hormuz after Iran responded to U.S.-Israeli attacks by using drones, missiles and mines to \u200ceffectively close the channel for tankers.
Krafton responds to Subnautica 2 legal ruling: "we are evaluating our options as we determine our path forward"
Krafton has issued a statement in response to a legal ruling yesterday, which pushed for CEO Ted Gill to be reinstated to the Subnautica 2 studio.
Samsung finally responds to complaints about the Galaxy S26 Ultra's headline feature, but the explanation ...
The feature is definitely not as perfect as you would expect.
POLITICO Correspondent reports the WH wants countries to ‘participate performatively’ in Strait of Hormuz
Colorado voters will decide whether transgender students can join girls’ sports
A ballot initiative that would require student athletes to only join sports teams that correspond to their biological sex has qualified for the November ballot, according to the Colorado Secretary of State’s Office. The measure includes a declaration that “males and females possess unique and immutable biological differences that manifest prior to birth and increase […]
Free Health Screenings & Safety Demos Scheduled For Thursday
Emergency responders and health care providers are hosting a free community event this week for local residents.
Sen. Schmitt accuses Democrats of playing ‘petty politics’ as DHS funding fight continues
Sen. Eric Schmitt, R-Mo., discusses the mounting national security concerns amid the DHS shutdown, responds to Democratic criticism of ICE and more on ‘America’s Newsroom.’
No H.I.V. Aid Without More Access to Minerals: U.S. Ponders ‘Sticks’ Against Zambia
A draft State Department memo outlines ways the Trump administration may ratchet up pressure on the African country by ending health support “on a massive scale.”
Slot responds to Liverpool boos after late Tottenham equaliser
Arne Slot admitted he understands the frustration from supporters after the Reds were booed at full-time following the 1-1 draw with Tottenham at Anfield.DOWNLOAD THE OFFICIAL EMPIRE OF THE KOP APP FO...
Eau Claire business damaged in fire
Crews responded to the scene on S. Barstow St. early Sunday morning.
Salonen: Not everything is about politics, as it turns out
I don’t always return to my writings following publication to check on reader reactions, but when I notice a vigorous response, I might, like with my Feb. 15 “barking dog” column, in which I made the case for not having to publicly respond to every social outburst.
How Investors May Respond To Flutter Entertainment (FLUT) Earnings Miss Amid New US$250 Million Buyback
Flutter Entertainment’s latest results showed Q4 revenue of US$4.74 billion, up 24.9% year on year but below analyst forecasts for both revenue and earnings per share. On the same day, the company also launched the fifth tranche of its multi‑year share repurchase program, authorizing Goldman Sachs to buy back up to US$250 million of shares to reduce its share count. We’ll now examine how Flutter’s Q4 earnings miss against analyst expectations reshapes the previously optimistic investment...
2nd annual mental health summit focuses on support, resources for first responders
The mental health of first responders is getting special attention in western North Carolina during a three-day summit in Buncombe County.
Passenger’s mental health episode turns ferry around - The Martha's Vineyard Times
A Vineyard Haven man’s mental health episode forced a Steamship Authority ferry to turn around and head back to Woods Hole shortly after departing this week. On Tuesday morning, Falmouth Police responded to the ferry terminal in Woods Hole for what was described as a “disruptive passenger” aboard the passenger ferry M/V Woods Hole shortly […]
‘Hypocritical BS’: Democratic Congressman responds to GOP attacks on DHS funding
Chattanooga Tourism Co. addresses concerns as county looks to shift funds to sports
TheChattanooga Tourism Company is responding to concerns that were raised during a vote by Hamilton County commissioners tomove thousands of dollars away from
8 hospitalized during Temple Israel attack in West Bloomfield, Henry Ford Health says
Henry Ford Health says eight first responders were injured in the Temple Israel attack in West Bloomfield.
8 first responders hospitalized after West Bloomfield temple attack
Henry Ford Health confirmed that eight first responders are being cared for at two of its hospitals after an attack at a West Bloomfield temple.
These swing voters don’t like or understand the reason for the war in Iran
NPR reporters observed focus groups of 12 swing voters from Michigan. We discuss their thoughts on the war in Iran and what they wish President Trump would focus on.This episode: voting correspondent Miles Parks, political correspondent Ashley Lopez, and senior national political correspondent Mara Liasson.This podcast was produced by Casey Morell and Bria Suggs, and edited by Rachel Baye.Our executive producer is Muthoni Muturi.Listen to every episode of the NPR Politics Podcast sponsor-free, unlock access to bonus episodes with more from the NPR Politics team, and support public media when you sign up for The NPR Politics Podcast+ at plus.npr.org/politics.
Anthropic’s Claude AI can respond with charts, diagrams, and other visuals now
Claude can now help you visualize topics as you chat.
Rochester police fatally shoot man while responding to mental health crisis call, officials say
According to Rochester Police, officers were dispatched around 9:30 p.m. to the 1900 block of Ashland Drive Northwest. The call was domestic-related, police say.
Millions of Americans are skipping meals or cutting back on utilities to afford health care
Roughly one-third of respondents – equivalent to more than 82 million Americans – said they have had to cut back on at least one daily living expense to cover their health care bills, according to a new survey.
National People's Congress: China's biggest political meeting is ending - what have we learned?
BBC correspondents give us their biggest takeaways from China's National People's Congress.
The toll the war in Iran has on the U.S. economy
The United States’ war in Iran is roiling global oil markets. We discuss how that affects the American economy — not just at the gas pump — and how those economic challenges are playing in this year’s elections.This episode: voting correspondent Miles Parks, chief economics correspondent Scott Horsley, and senior political editor and correspondent Domenico Montanaro.This podcast was produced by Casey Morell and Bria Suggs, and edited by Rachel Baye.Our executive producer is Muthoni Muturi.Listen to every episode of the NPR Politics Podcast sponsor-free, unlock access to bonus episodes with more from the NPR Politics team, and support public media when you sign up for The NPR Politics Podcast+ at plus.npr.org/politics.
'Teen Mom 2' star Jenelle Evans' son checked into mental health facility: report
Evans' son Jace allegedly threatened to kill himself and his grandmother last month and officers responded to a "troubled teen disturbance."
'Teen Mom 2' star Jenelle Evans' son checked into mental health facility: report
Evans' son Jace allegedly threatened to kill himself and his grandmother last month and officers responded to a "troubled teen disturbance."
Valve responds to NY Attorney General lawsuit: "We have serious concerns with the alterations the NYAG claims are necessary to make to our games"
Valve has responded to New York Attorney General Letitia James' lawsuit against the firm, stating it does not believe t…
First responders light up the night for young patients at Penn State Health Golisano Children’s Hospital
More than 100 emergency vehicles lit up the campus of Penn State Health Golisano Children’s Hospital on Tuesday evening, creating a colorful display during the fifth annual Light Up the Night…
After using MacBook Neo, it's clear Windows needs to rethink its PC strategy (and fast)
Apple's new $599 laptop will force Windows PCs and Chromebooks to respond in turn. That's a good thing.
Smart Plants in a Changing World Science
The Salk Institute is teaming up with the Del Mar Foundation for a three-part webinar series to highlight Salk's foundational research in brain health, cancer, and agriculture. Join us on Wednesday, March 11, at 10 a.m. to learn directly from Salk scientist Lucia Strader about how plants sense and respond to their environments, and how understanding these natural survival strategies can help us develop crops that thrive in a changing world. The Del Mar Foundation is offering a 1:1 Challenge Match through June. Gifts made during the webinar series will be matched dollar-for-dollar, doubling your impact on critical research. Donors who give $1,000 or more to an area of greatest need will also join the Discovery Society, with special access to Salk news and events. Salk Institute on Facebook / Instagram
ICE is keeping tabs on American citizens
Immigration and Customs Enforcement has been using a variety of tools to keep tabs on not just immigrants the agency intends to deport but also U.S. citizens who publicly oppose the agency’s tactics. We discuss what that surveillance looks like and what the impact is for people whose activity the agency has tracked. This episode: voting correspondent Miles Parks, reporter Kat Lonsdorf, and power and influence reporter Jude Joffe-Block.This podcast was produced by Casey Morell and Bria Suggs, and edited by Rachel Baye.Our executive producer is Muthoni Muturi.Listen to every episode of the NPR Politics Podcast sponsor-free, unlock access to bonus episodes with more from the NPR Politics team, and support public media when you sign up for The NPR Politics Podcast+ at plus.npr.org/politics.
Surveys show owners of this older Galaxy phone aren’t rushing to upgrade to the S26
We ran two surveys asking whether Galaxy S23 owners should upgrade to the Galaxy S26 series. Here’s how you responded.
Bay City Fireworks Festival responds to concerns about band performance
The organizers of the Bay City Fireworks Festival are responding to concerns about one of the bands booked to play at this year’s festival.
Crews monitoring carbon monoxide levels at health care facility
Emergency crews responding to reports of elevated carbon monoxide are ventilating a senior living facility.
New NAACP, Sanofi Report Unveils Roadmap for Advancing Health Equity Across the Country
The NAACP, in collaboration with Sanofi, released the findings of the ACE Your Health Community Wellness Survey, one of the largest contemporary grassroots assessments of community health resources in the United States. The report, with nearly 23,000 respondents across 47 states, Washington, D.C., and Puerto Rico, provides insights into the real-world conditions that drive health outcomes, from the quality of housing and access to transportation to the pervasive impact of chronic stress.
Buc-ee’s is loved by shoppers, so why did it get red-flagged by the Better Business Bureau? Here’s what you need to know
Despite its popularity with loyal customers, apparently the growing Texas-based gas station chain isn’t so great at responding to complaints.
NBA cancels Atlanta Hawks' plans to celebrate famed Magic City adult entertainment club
The NBA has called off the Atlanta Hawks’ plans for a night of celebrating the city’s famed Magic City adult entertainment club, saying it was responding to “concerns” from many […]
'Entertainment Tonight' Names Emily Curl As NY-Based Correspondent
'Entertainment Tonight' has brought on Emily Curl as a New York–based correspondent. She begins her new role today, March 9.
Poll: Most Americans oppose war in Iran, but most Republicans support it
A majority of Americans oppose the United States' military action in Iran, according to a new NPR/PBS News/Marist poll. However, that opposition breaks down along party lines, with a majority of Republicans saying they support the war. We discuss whether the lack of public support could alter President Trump's next steps and how the war could affect this year's midterm elections.This episode: voting correspondent Miles Parks, senior White House correspondent Tamara Keith, and senior political editor and correspondent Domenico Montanaro.This podcast was produced by Casey Morell and Bria Suggs, and edited by Rachel Baye. Our executive producer is Muthoni Muturi.Listen to every episode of the NPR Politics Podcast sponsor-free, unlock access to bonus episodes with more from the NPR Politics team, and support public media when you sign up for The NPR Politics Podcast+ at plus.npr.org/politics.
Worker rescued after being trapped under pipe at Lee Health Cape Coral construction site
The Cape Coral Fire Department said crews are responding to help a construction worker who got trapped under a pipe.
Mentalist Oz Pearlman reads Dana Bash’s mind ahead of his performance at the White House Correspondents’ Dinner
Scientists found a surprising way to make exercise work better
Exercise normally boosts the body’s ability to use oxygen, a key marker of health and longevity — but high blood sugar can block that benefit. Researchers found that a ketogenic diet helped mice normalize blood sugar and dramatically improved how their muscles responded to exercise. Their muscles became better at using oxygen and built more endurance fibers. The results suggest diet and exercise may work together in surprising ways to improve metabolic health.
Are prediction markets just sports betting by another name? How legal battles are taking shape
Prediction markets present a new asset class that is moving faster than regulation. How are sportsbooks, and lawmakers, responding?
What crocodile bones teach us about dinosaurs
Paleontologists have often determined how old a dinosaur was by counting the growth rings in its bones. Just like with trees, it was thought that each ring corresponded to a single year of age. But researchers who studied crocodiles at an outdoor recreation center near Cape Town appear to have poked a hole in that approach. In the crocodiles, which are some of the closest living relatives of dinosaurs, there was more than one growth ring laid down per year. The results contribute to a growing debate over the best way to age animals.Read more of freelance science reporter Ari Daniel’s story here.Interested in more on the future of science? Email us your question at shortwave@npr.org.Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.
Tim Cook Says Two Things Matter Most at Apple Ahead of Company's 50th Anniversary
CBS Sunday Morning correspondent David Pogue interviewed Apple's CEO Tim Cook ahead of the company's 50th anniversary on April 1, 2026. In the interview, Cook revealed the two things that are "essential" to Apple: people and culture. "Yes, we have a lot of intellectual property and so forth, and that is important, but it's people that create that intellectual property," said Cook.
Annual ice hockey tournament raises funds for free mental health care for first responders
Rochester, N.Y. — The third annual Guardian’s Cup took place at Tim Hortons Iceplex this weekend.This year's tournament featured 32 teams of first responders a
‘Unforgivable under any circumstances’: Sen. Murphy responds to analysis that US likely responsible for Iran school strike
‘Get used to it’: Jake Tapper responds to Trump admin’s criticism of Iran war coverage
LAPD officers respond to business robbery call, fatally shoot suspect behind counter
Officers with the Los Angeles Police Department opened fire on a suspect while responding to a robbery call late Saturday night. According to the LAPD Public Information Officer, units were called …
Readers respond: Trump administration assaults science, health care
Letters to the Editor can be submitted to letters@oregonian.com with full name and place of residence.
Readers respond: Trump administration assaults science, health care
Letters to the Editor can be submitted to letters@oregonian.com with full name and place of residence.
Poll: Primary voters prize ideology over electability, as their parties get low marks
A higher share of Democratic voters than Republican voters prioritize backing primary candidates who can win, but poll respondents say it's complicated.
Readers respond: Medicare’s broken system for home health care
Letters to the Editor can be submitted to letters@oregonian.com with full name and place of residence.
Oneida County awarded $60K to support first responder mental health
Oneida County has been awarded a grant to implement a comprehensive wellness initiative designed to support first responders and uniformed personnel.
Authorities respond to fire at Cedar Rapids business
Authorities said they were called to 3815 16th Ave. SW for a fire at 8:10 pm.
Apple's Strange TikTok Videos Capturing Gen Z's Attention
Apple is promoting the MacBook Neo with a series of intentionally strange TikTok videos that are successfully capturing Gen Z's attention. Since Thursday, Apple has been posting the videos in sets of three, with each video corresponding to one of the MacBook Neo's Blush, Citrus, and Indigo color options. The laptop also comes in Silver, so there may be a final set of videos tomorrow.
Gov. Mills responds to Dr. Oz’s request for MaineCare data
Last month, the U.S. Centers for Medicare and Medicaid Services gave Maine 30 days to answer questions about how the state handles MaineCare following a federal audit that found $46 million in alleged “improper” payments.
As WA grocery stores shutter, lawmakers struggle to respond
Four of five bills in the Legislature meant to prevent grocery closures stalled out under industry pressure, in a short session dominated by a wealth tax debate.
Bungie Responds Quickly to Marathon Microtransactions Backlash, First Patch Will Make the Game Slightly Easier
Bungie has revealed plans to change Marathon in some key ways just a few days after launch, outlining early patch notes for an update due out next week.