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Kalshi says it will crack down on politicians and athletes betting
Kalshi said the new features were aimed at preventing "bad actors" in sports and politics from engaging in insider trading.
Trump administration adds State Health Officer Dr. Daniel Edney to short list of nominees for CDC director
State Health Officer Dr. Dan Edney is among the contenders to head the nation’s Centers for Disease Control and Prevention, the Washington Post reported
Microsoft Exchange Online service change causes email access issues
Microsoft is working to address an ongoing service issue that has intermittently prevented some users from accessing their cloud-based Exchange Online mailboxes via Outlook mobile and Mac desktop clients since Thursday.
How ‘Tiny Shortcuts’ Are Poisoning Science
Seemingly harmless data tweaks are undermining the integrity of the entire field. We must define the problem to prevent it.
Precision Nutrition: Tufts University Expert Q&A On How Personalized Diet Science May Transform Health - Where The Food Comes From
Tufts expert José Ordovás explains precision nutrition and how personalized diet science could transform health and prevent disease.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Wake County childcare centers take preventive measures as measles cases rise
It's not just vaccines — parents are refusing other routine preventive care for newborns
Doctors are alarmed that skepticism fueled by rising anti-science sentiment is increasingly reaching beyond vaccines to other proven, routine, preventive care for babies.
Why mosquitoes always find you and how they decide to attack
Scientists have finally cracked how mosquitoes decide where to fly—and it’s not by following each other. Instead, each insect independently reacts to visual cues and carbon dioxide, zeroing in on humans when both signals align. Dark colors and CO2 together create the strongest attraction, triggering swarming and biting behavior. This insight could reshape how we design traps and prevent mosquito-borne diseases.
Sacramento businesses recover after string of burglaries; 1 suspect arrested
Sacramento police have arrested a man believed to be connected to 11 burglaries affecting local businesses, as authorities work to prevent further incidents.
One arrested, another cited in shoplifting incident at business on East Avenue in Chico
CHICO, Calif. - A Paradise man was arrested and a Forbestown woman was cited by Chico Police in connection to a shoplifting incident at a business in Chico.The Chico Police Department says that at around 12:30 p.m. on Wednesday, March 18, a loss prevention employee observed two suspects stealing several items from a retail business on the 700 block of East Avenue in Chico.Upon exiting the building, the two suspects, a man and a woman, were contacted by the loss prevention employee regarding the stolen items. The employee was able to persuade both suspects to return to the store and hand over the items they had stolen.Authorities say the business expressed their desire to press charges against the suspects and contacted Chico Police to report the crime.Officers reviewed video surveillance that confirmed the employee's account of what happened. Officers then made arraignment for both suspects to turn themselves in the following day.When the suspects, identified as 51-year-old Jamie Leal of Forbestown and 62-year-old Melvin Royal of Paradise, arrived the next day to turn themselves in, authorities say both admitted to their involvement in the incident and elected to write handwritten apology letters to the business.Leal was cited by Chico Police on a misdemeanor charge of shoplifting.Royal was taken into custody and transported to the Butte County Jail, where he was booked on the following charges:Shoplifting with 2+ priors (felony)Shoplifting (misdemeanor) googletag.cmd.push(function() { googletag.display('ad-1514992'); });
Short-Term Cuts, Long-Term Costs: Investing in Health Care for All Californians
Providing health care for all Californians improves health, strengthens communities, and prevents higher long-term costs.
Four Key Moments: Hearing on Improving Kidney Health Through Better Prevention and Innovative Treatment
WASHINGTON, D.C. – Medicare’s coverage and reimbursement policies for chronic kidney disease (CKD), and its most severe form, end-stage renal disease...
1,800-year-old nails discovered in 3 burials in Roman necropolis, possibly to 'protect' both the living and the dead
Archaeologists excavating in Rome's Ostiense necropolis found three skeletons with iron nails on their chests, hinting at a ritual to prevent restless spirits.
RFK Jr. makes food sound like a miracle drug. Researchers say he often overstates the science
In the Trump administration’s campaign to promote healthy eating, Robert F. Kennedy Jr. has not stopped at his slogan urging people to “eat real food” to prevent disease. In recent speeches and…
RFK Jr. Makes Food Sound Like a Miracle Drug. Researchers Say He Often Overstates the Science
In the Trump administration’s campaign to promote healthy eating, Robert F. Kennedy Jr. has not stopped at his slogan urging people to “eat real food” to prevent disease. In recent speeches and podcast appearances, the nation’s health secretary also has claimed that diet can “cure” schizophrenia and ...
RFK Jr. Makes Food Sound Like a Miracle Drug. Researchers Say He Often Overstates the Science
In the Trump administration’s campaign to promote healthy eating, Robert F. Kennedy Jr. has not stopped at his slogan urging people to “eat real food” to prevent disease. In recent speeches and podcast appearances, the nation’s health secretary also has claimed that diet can “cure” schizophrenia and ...
German Health Minister Nina Warken and WHO Hub in Berlin highlight 2025 achievements
Germany’s Federal Minister of Health, Nina Warken, visited the WHO Hub for Pandemic and Epidemic Intelligence in Berlin today to review progress and launch its 2025 Annual Report. The report highlights advances in using artificial intelligence, data science and pathogen genomics to strengthen global preparedness for future pandemics.In 2025, the WHO Hub in Berlin worked with more than 160 Member States and over 190 partners to help countries and organizations develop new systems and tools to detect and understand new public health threats as quickly as possible, whenever and wherever they occur.BMG to confirm whether they wish to contribute a quote. “Detecting outbreaks early is one of the most effective ways to save lives and prevent epidemics from becoming global crises,” said Federal Minister of Health Nina Warken. “Germany is proud to host and support the WHO Hub for Pandemic and Epidemic Intelligence. Its work strengthens our safety at home and helps protect people worldwide.”Artificial intelligence is increasingly transforming the detection of outbreaks. In 2025, the Hub launched an upgraded version of the Epidemic Intelligence from Open Sources (EIOS) system, which uses enhanced AI functions to scan global online information in real time and help experts quickly identify unusual health events. The system is now used by 120 countries.To better anticipate health threats, countries need information beyond traditional health data. The Hub supports countries in implementing Collaborative Surveillance, which integrates data on climate, animals, travel, and population movement to provide a more comprehensive and real-time understanding of health threats.The Hub also expanded global access to pathogen genomics, which helps scientists detect new pathogens, such as viruses and bacteria, understand how they spread and how dangerous they may become. Through the International Pathogen Surveillance Network (IPSN), the WHO Hub in Berlin worked with 309 partners in 101 countries to expand access to these technologies.“We are in a new era of global health threats, and we need new tools to face tomorrow’s challenges,” said Dr Chikwe Ihekweazu, Executive Director of the WHO Health Emergencies Programme. “The WHO Hub in Berlin helps countries use data and technology more effectively so they can identify risks earlier and respond faster. No country can address these threats alone. Strong cooperation remains our best defence.”“Berlin offers an ideal environment for our work. We collaborate closely with world-leading institutions such as the Robert Koch Institute and the Charité Center for Global Health,” said Dr Oliver Morgan, Head of the WHO Hub for Pandemic and Epidemic Intelligence. “Germany has supported the WHO Hub since its establishment, and we are pleased to welcome Federal Minister Nina Warken to the Hub today. This strong partnership helps us advance innovation in pandemic and epidemic intelligence and better support countries to prepare for future health threats.”The Hub is expanding the use of advanced analytics and mathematical modelling to forecast how outbreaks may develop and to assess which response measures are most effective. Through its Collaboratory, the Hub connects modelers and analysts with governments to ensure their work addresses real public health needs. In 2025, the community grew to 1300 members from 50 countries and 200 institutions. An AI-powered pandemic simulator, currently in the prototyping phase, will help decision-makers compare outbreak scenarios and help identify effective disease control measures.
Sandhills Calving System continues to protect calf health, ranch profitability
Twenty-five years ago, a collaboration between a Sandhills ranch family, a rural veterinarian and Husker researchers led to a management innovation that transformed how cattle producers prevent calf scours. Known today as the Sandhills Calving System, the approach has become one of the most widely recommended strategies for preventing neonatal calf diarrhea.
Ban corporate donations to UK political parties to protect elections, says thinktank
CenTax warns bill under debate in parliament has ‘easily exploitable’ loopholes and will not prevent foreign interference
The heart health steps now recommended you take in your 20s and 30s
People between ages 20 and 40 should be taking steps now to prevent heart attacks and strokes, according to new recommendations from the American Heart Association.
Apple Cracks Down on ‘Vibe Coding’ Apps
Apple has quietly prevented AI vibe coding apps such as Replit and Vibecode, which help people create games and other applications, from releasing updates to their mobile apps on the App Store unless they make modifications, according to several people with knowledge of the situation. The ...
Survey Findings: Integrating Sexual and Reproductive Health into UHC Requires Leadership, Financing, and Political Will
SRHR remains critically underfunded, leaving 164M women with unmet needs and driving preventable maternal deaths. Global survey findings show political commitment is the key driver of financing and integration into UHC. While fiscal constraints persist, leadership determines whether resources are prioritized, enabling equitable access and strengthening health systems.
Calvin Ridley shouldn’t prevent Titans from drafting a WR
The Tennessee Titans will enter the 2026 NFL Draft with a long-term need for a No. 1 wide receiver.
Progress in reducing child deaths slows as 4.9 million children die before age five
An estimated 4.9 million children died before their fifth birthday in 2024, including 2.3 million newborns, according to new estimates released today. Most of these deaths are preventable with proven, low-cost interventions and access to quality health care.
Bipartisan Science of Reading Bill Passes House Committee
The legislation would prevent states from allowing what one member called ‘discredited approaches.’
New Washington state law aims to protect access to preventative health care
A new law in Washington state is aimed at protecting access to preventative health care.Governor Bob Ferguson recently signed House Bill 2242 into law. It's a
US lawmakers Murphy, Casar push legislation to regulate prediction markets
The legislation aims to prevent bets made based on insider knowledge of wars, economic policy and controllable events.
Federal judge extends order blocking Trump admin's cuts to Illinois public health funding
The loss in grant funding would have wiped out some HIV tracking programs, family planning initiatives and lead poisoning prevention.
Consumer Reports: Preventing kids' sports injuries
Consumer Reports has important advice for parents on how to help prevent common and often avoidable sports injuries.
New obesity statistics highlight importance of preventive cardiology
Cardiovascular health is much worse in some parts of the United States than others. Cardiologists in those high-risk areas can make a world of difference by embracing preventive cardiology and working to treat patients before it is too late.
Large rapamycin clinical trial launches at UT Health San Antonio - UT Health San Antonio
A drug once known almost exclusively for preventing organ transplant rejection is now at the center of a National Institute on Aging-funded clinical study at UT Health San Antonio, the academic health center of The University of Texas at San Antonio (UT San Antonio), to determine how rapamycin should be used in older adults to […]
1 Food Women Should Eat More Of To Prevent Menopause Symptoms
In TODAY.com's Expert Tip of the Day, a dietitian reveals the "incredibly important" diet change to make as women go through menopause.
St. Luke’s Episcopal hosts community dinner on youth mental health
Church brings together residents to discuss adolescent well-being, grief, and suicide prevention.
Winter Sports and Lower Limb Motor Disability
People with lower limb motor disability need tailored equipment, training, and medical oversight to boost performance while preventing upper limb overload and skin problems.
Dallas Goedert, Eagles agree to new 1-year contract
The Eagles prevented a $20 million dead cap hit by finalizing a new deal with Dallas Goedert.
Low-cost preventive measures could mitigate spread of bacteria causing neonatal mortality
A new study found that a multifaceted infection prevention and control intervention could at least temporarily thwart outbreaks of infections from the Klebsiella pneumoniae bacterium, a leading cause ...
Outgoing Maine hospital lobbyist says health costs can’t be stopped
Steven Michaud discusses Maine's healthcare affordability challenges, hospital changes, and the need for disease prevention and management.
Linux Finally Catches Up to Windows with a Game-Changing Performance Feature
For years, the Linux kernel’s scheduler has been world‑class at balancing loads, yet it missed a crucial, cache‑aware instinct. In modern multi‑core systems, that gap can turn into measurable latency, especially when threads bounce between cores that don’t share the same cache. A new upstream feature, often called Cache Aware Scheduling, is now set to change that equation. A cache‑savvy scheduler arrives At the heart of any OS, the scheduler decides which thread runs where and for how long. In modern CPUs, small private caches (L1 and L2) sit beside each core, while a larger Last Level Cache (LLC, typically L3) is shared among groups of cores. When a task migrates across LLC boundaries, its warm data may vanish from the cache, forcing slower trips to main memory. Cache Aware Scheduling keeps related tasks close to their shared LLC, reducing destructive migrations. By respecting cache topology, the kernel minimizes cold‑start penalties and preserves locality that many workloads desperately need. The result is less thrashing, fewer memory stalls, and more consistent throughput. "Keep tasks close to their data, and the system will keep performance close to its peak." Why this narrows the Windows gap Windows has long leaned on topology‑aware, cache‑sensitive heuristics, especially since the Windows 10 era. That advantage helped Microsoft handle hybrid designs with P‑cores and E‑cores, plus complex cluster and NUMA layouts. With cache awareness integrated upstream, Linux brings parity to this vital dimension, without sacrificing its trademark flexibility. The Linux approach remains deeply configurable, reflecting the ecosystem’s breadth across servers, desktops, and embedded devices. It layers atop existing NUMA‑balancing and energy‑aware logic, refining placement rather than reinventing the wheel. Crucially, it aligns scheduling with the hardware’s real shape, not just with abstract CPU counts. Real‑world gains and who benefits Early tests on Intel Sapphire Rapids platforms point to gains in the 30–45% range for select workloads. Those wins appear in cache‑sensitive tasks like in‑memory analytics, high‑thread compilation, and microservices with tight working‑sets. Games and latency‑bound engines can also feel steadier frame‑times, especially when threads share hot assets. The benefits extend to AMD’s 3D V‑Cache parts, where keeping threads near enlarged cache slices prevents needless misses. Hybrid x86 designs with performance and efficiency cores further profit when cache and core roles are scheduled in concert. Even handhelds running SteamOS can squeeze more out of limited power, translating cache locality into smoother play. Key advantages include: Lower end‑to‑end latency Fewer expensive misses to RAM Better multi‑socket and NUMA behavior Improved energy efficiency More predictable QoS under mixed loads Stronger scaling on dense servers Caveats, tuning, and rollout No scheduler change is purely free, and trade‑offs still exist. Favoring locality can reduce cross‑cluster balance if limits are set too tight. Likewise, fairness and utilization must remain healthy, especially under heterogeneous, bursty workloads. Linux’s implementation is designed to be measured and tunable, not a blunt instrument. It cooperates with energy‑aware scheduling for mobile efficiency, and with NUMA‑balancers on big iron. Expect architecture‑specific refinements as vendors surface richer topology hints and cache‑sharing maps. Upstream integration has begun, with broad distribution adoption likely over the next cycles. Many users will encounter the change through standard kernel updates in 2025–2026, depending on distro cadence. Server‑class kernels may enable or tune it sooner for targeted fleets where cache locality is money in the bank. How to think about performance impact Cache Aware Scheduling amplifies gains when your workload is both CPU‑bound and cache‑sensitive. Think tight inner loops, hot code paths, and datasets that fit snugly in shared LLC. It’s less dramatic for I/O‑bound services or memory‑hungry tasks that blow past cache capacity. Still, even modest locality improvements often translate into smoother tail‑latency, which is where user experience and SLAs typically break. Developers can further help by pinning related threads, batching work, and aligning data to reduce cross‑cluster chatter. The scheduler’s new awareness works best when applications expose good hints. The bottom line By understanding and honoring cache topology, Linux removes a subtle yet costly bottleneck. The kernel’s smarter placement keeps hot data hot and work near where it belongs. That narrows a long‑standing gap with Windows, while preserving the openness and tunability Linux champions. For gamers, creators, and operators, the payoff is practical: more consistent frames, faster builds, and snappier services. For the ecosystem, it’s another step toward hardware‑savvy scheduling that turns transistor complexity into real‑world speed. And for Linux itself, it’s a timely upgrade that matches today’s silicon with tomorrow’s expectations.
Why Pentesting Is Important For Small Businesses
Learn why businesses need penetration testing to identify vulnerabilities, prevent breaches and strengthen cybersecurity defenses as cyber threats rise.
Boebert challenger Eileen Laubacher joins lawsuit aimed at blocking her from Democratic assembly
A Denver District Court judge on Thursday permitted Democratic congressional candidate Eileen Laubacher to join a lawsuit filed by one of her primary opponents seeking to prevent Laubacher from participating in the party’s assembly process in a bid to qualify for Colorado’s primary ballot. Laubacher is one of four Democrats running for the nomination to […]
Earlier Cholesterol Testing Can Reduce Heart Attacks and Strokes, New Guideline Says
Eleven medical organizations advised changes to preventive cardiac care that it says could markedly reduce heart attacks and strokes.
Democratic senators file war powers resolution to check Trump on Cuba
Senate Democrats have filed legislation that would prevent the U.S. from attacking Cuba without congressional approval as they seek to force a vote on President Donald Trump's stated goal of a “takeover” of the Caribbean country.
Google Fixes Two Chrome Zero-Days Exploited in the Wild Affecting Skia and V8
Google patches two Chrome zero-days exploited in the wild, urging updates to version 146.0.7680.75/76 to prevent attacks.
Bridging Gaps in Women’s Health: From pregnancy to long-term prevention
Rethinking postpartum care, addressing social needs and partnering with communities can help prevent disease and improve women’s health long before complications arise.
The world just smashed the emergency glass on oil prices. Now it’s up to Trump for a long-term fix
Dozens of countries have done the unprecedented, releasing an historic amount of crude from emergency reserves to prevent high oil prices from crippling the economy. If that doesn’t work, there’s only one serious option left: ending the war and opening the Strait of Hormuz.
Momentum builds for a federal office of men’s health focused on disease prevention
For advocates who have been pushing to create a federal office of men's health, this could finally be the moment.
Whooping Cough Continues Wyoming Spread - Wyoming Department of Health
Wyoming Department of Health (WDH) officials are concerned about the ongoing, active spread of pertussis (whooping cough) across the state. Kaylyn Friesen, vaccine-preventable disease epidemiologist with WDH, said there have been 26 confirmed pertussis cases in Wyoming so far this year. “While roughly two-thirds of the reported cases have been among Fremont County residents, pertussis […]
Housing proposal threatens build-to-rent business model
A bipartisan housing proposal in the U.S. Senate could reshape the rapidly growing single-family rental market by forcing large institutional investors to sell newly built rental homes within seven years, The Wall Street Journal writes. Supporters say the measure would help expand homeownership by preventing deep-pocketed investors from holding large inventories of houses that might […]
Fierce Healthcare Names Escher Health a “Fierce 15” Company of 2026
OAKLAND, Calif., March 09, 2026 (GLOBE NEWSWIRE) -- Escher Health, a leader in healthcare financial AI, today announced that Fierce Healthcare has named it as one of 2026’s “Fierce 15” healthcare companies. The annual special report features the most innovative private healthcare companies looking to change the face of the industry. “Navigating safety net programs, including Medicaid, remains stubbornly complex, preventing people from receiving needed care until it’s urgent and expensive,” said
Congress plans new response to health cyberattacks
The plan puts the burden on the government and providers to prevent serious breaches that cut across the industry.
Can Collagen Really Improve Your Skin Health? What the Research Says
A recent review of clinical research suggests that collagen supplements may offer modest improvements in skin elasticity and hydration. There is little evidence to show that collagen can prevent or significantly reverse wrinkles, despite common marketing claims.
Dan Hurley Ejected In Final Second of Marquette's 68-62 Win Over No. 4 UConn
Marquette hung on for a 68-62 victory that prevented No. 4 UConn from claiming a share of the Big East regular-season title.
UiPath Expands Into Healthcare AI As Valuation Lags Analyst Targets
UiPath (NYSE:PATH) has launched agentic AI automation tools tailored for healthcare providers and payers. The company is partnering with Genzeon to target data management and revenue cycle workflows. Use cases include medical records summarization, claim denial prevention, and prior authorization processing. For investors following NYSE:PATH, this move takes the company deeper into healthcare, a sector where many workflows still rely on manual processes and fragmented systems. UiPath built...
As WA grocery stores shutter, lawmakers struggle to respond
Four of five bills in the Legislature meant to prevent grocery closures stalled out under industry pressure, in a short session dominated by a wealth tax debate.
Scientists discover protein that triggers diabetic blindness
A newly identified protein may hold the key to preventing diabetic blindness. Researchers discovered that LRG1 triggers the earliest damage in diabetic retinopathy by constricting tiny retinal blood vessels and reducing oxygen supply. In mice, shutting down this protein stopped the damage before it could take hold. The finding could pave the way for treatments that protect vision before symptoms ever begin.
Diamantis scandal, ‘superfund’ bill, DHS: CT politics news
Plus: Proposals for overdose prevention centers, private equity protections in health care, and a 'Golden Girls Bill.'
SAMHSA Announces More Than $69 Million in Funding Opportunities for Serious Mental Illness and Suicide Prevention Grant Programs
SAMHSA announced $69.1 million in funding for: the Children's Mental Health Initiative (CMHI), Zero Suicide, and Assisted Outpatient Treatment (AOT).
Carbon emissions now more than double the planetary boundary, analysis finds
Earth is not infinite. Pollution beyond certain levels threatens the climate and ecosystems. To prevent this, scientists have proposed planetary boundaries, defining the safe operating limits of the Earth ...
Adial Pharmaceuticals Reports 2025 Fiscal Year Financial Results and Provides Business Update
GLEN ALLEN, Va., March 06, 2026 (GLOBE NEWSWIRE) -- Adial Pharmaceuticals, Inc. (NASDAQ: ADIL) (“Adial” or the “Company”), a clinical-stage biopharmaceutical company focused on developing therapies for the treatment and prevention of addiction and related disorders, today provided a business update and reported its financial results for the 2025 fiscal year ended December 31, 2025. Key Highlights: Regulatory Progress: Achieved positive clinical study results from the AD04-103 pharmacokinetics (P
U.S. needs a national prevention infrastructure for mental and behavioral disorders
A clear blueprint for a national prevention infrastructure for mental and behavioral disorders.
How does hair loss differ between men and women?
Learn how men’s and women’s hair loss is treated differently and what you can do to prevent it.
GOP Sen. Steve Daines’ last-minute withdrawal from Senate race was meant to block Democrats from fielding a top-tier recruit
GOP Sen. Steve Daines made the last-minute decision to abruptly pull out of his Senate race to prevent Democrats from fielding a top recruit for the open Montana seat, according to two sources familiar with the matter.
US CDC staff to arrive in South Carolina to help contain measles outbreak
U.S. Centers for Disease Control and Prevention staff will arrive in South Carolina to help the state contain the largest measles outbreak in the country in more than 30 years, a state official said in a briefing on Wednesday.
Preventive health advisory panel meeting postponed for third time
The panel, which makes recommendations for cancer screenings and other guidelines, last met in March of 2025.
Digital Studio Helps Journalism, Entertainment and Social Media Sectors Drive Safe Storytelling on Suicide
The American Foundation for Suicide Prevention (AFSP) today launched its Safe Storytelling Studio, a digital content hub with resources and guidance on suicide safe storytelling. Intended for the entertainment industry, journalists and social media creators, the Studio features evidence-based guidance and case studies that equip storytellers with the confidence to safely elevate our culture's understanding of suicide and mental health. To explore the Safe Storytelling Studio, visit storytelling.
Wake County to host measles edition of Ask the Doc Town Hall
Wake County Public Health will hold a special measles-focused Ask the Doc Town Hall on March 10 at 6 p.m., offering residents a chance to learn about symptoms, risks, prevention, and vaccination from local medical experts via Zoom or Facebook Live.
Phillies' Johan Rojas facing suspension for violating drug program
Johan Rojas is facing an 80-game suspension after violating Major League Baseball’s Joint Drug Prevention and Treatment Program.
Exclusive: March meeting of U.S. Preventive Services Task Force postponed
The March meeting of the U.S. advisory panel that determines what cancer screenings and other preventive health measures insurers must cover has been postponed, according to a spokesman for the U.S. Department of Health and Human Services.
Supreme Court sides with parents in trans fight
The court ruled that California schools cannot prevent teachers from notifying parents about their child’s gender identity
Harmony Health Foundation Expands Community Oral Health Access with Dentistry.One
Dentistry.One, a virtual-first dental care solution, today announced a new collaboration with Harmony Health Foundation (HHF) to expand access to preventive dental care and oral health education through a saliva-based screening and virtual care program launching in Tennessee and expanding next to Idaho, with additional states to follow.
Health care access in Michigan to expand through new funding to CMU
Hundreds of Michigan children and families will have increased access to preventive health care — and future health care providers will gain more hands-on training — thanks to new funding for Central Michigan University’s Mobile Health Central.
World Birth Defects Day: “Behind every diagnosis is a story that deserves to be supported through strong public policies and strengthened health systems”
Interview with Pablo Durán, Regional Advisor on Perinatal and Neonatal Health at PAHOWashington, D.C., March 3, 2026 (PAHO) – Today marks World Birth Defects Day, an opportunity to raise awareness about a group of conditions that remain one of the leading causes of neonatal mortality and childhood disability in the Region of the Americas. Although many can be prevented or treated, thousands of families each year face diagnoses that require specialized care, continuous follow-up, and comprehensive support.
Acting CDC director Bhattacharya urges measles vaccines
Jay Bhattacharya, the recently appointed acting director of the Centers for Disease Control and Prevention (CDC), on Monday urged families to consider vaccinating against measles as outbreaks acros…
Trump’s neck rash is because of ‘preventative skin treatment,’ his doctor says
A new rash on the right side of President Donald Trump’s neck is the result of a cream that he’s using as a “preventative skin treatment,” his personal physician told CNN on Monday.
Tampa General earns top hospital honor for eighth consecutive year
Newsweek and Statista also recognized Tampa General as a leader in infection prevention.
The Cost of Measles and Public Health Implications
Understand the cost of measles, from a financial, health, and societal standpoint. Also, learn the best preventative measures while planning for impact.
Global webinar on core public health capacities to conduct ship inspections and issue ship sanitation certificates
Ships cross borders every day, connecting countries and serving as a backbone of the global economy. However, outbreaks onboard can disrupt maritime traffic, leading to significant economic and operational negative consequences. Without strong public health capacities to detect, prevent, and respond to public health risks on board ships, maritime travel can also become a pathway for the spread of infectious diseases. To support countries in strengthening these capacities, the World Health Organization (WHO) convened a two-day webinar on 11–12 February, bringing together more than 700 ship inspectors, port health officers, and public health authorities, primarily from the African, Eastern Mediterranean, and European Regions. The webinar came at a pivotal time. With the amended International Health Regulations entering into force on 19 September 2025, the need to focus on public health preparedness has never been greater. Strengthening public health capacities at borders, including onboard conveyances, is a cornerstone of global health security and central to the amended IHR.“The high level of attendance and active participation throughout the two days of the webinar highlighted the growing demand for technical guidance and capacity-building support in ship inspection and issuance of ship sanitation certificates”, said Dr Ninglan Wang, Head of the Borders, Mass Gatherings and Health Protection Measures (BMM) Unit at the Health Emergency Preparedness Department at WHO headquarters. “The dynamic interactions among experts and countries underscored the value of continued cross-border collaboration in the maritime sector and knowledge exchange in this area”. Conducting regular public health inspections on board ships for the issuance of ship sanitation certificates (SSCs) in accordance with the IHR requirements is crucial for ensuring that ships meet specific health standards, thereby minimizing the risk of the international spread of diseases via maritime traffic. These certificates, mandated by the IHR, require ports to have trained personnel who can identify and control public health risks on board vessels and apply recommended control measures. This standardized global procedure not only ensures compliance with the IHR but also promotes consistency in health practices across ports worldwide. SSCs are the globally-recognized tool used to prevent and control known public health risks on ships, providing a common way to register and communicate public health events and measures taken on board between all stakeholders involved in this process, including public health authorities in ports and ship operators. Only SSCs issued by ports authorized by national authorities to issue such certificates are considered valid. As per the IHR, all States Parties are required to send to WHO their list of authorized ports (available here) and to keep it updated. However, many Member States continue to face practical challenges, such as limited resources, high staff turnover, and competing priorities. These realities underscore the value of platforms such as this webinar, which foster collective learning, peer-to-peer exchange, and practical solutions to help countries build and sustain the capacities required under the IHR.Over the two days, participants engaged in presentations and discussions covering a wide range of technical and operational topics, such as the overarching international legal framework governing ship sanitation; considerations for pre-inspection planning; risk assessment factors by type of vessel; the completion and issuance of SSCs and evidence report forms; or practical insights on the inspection of various technical areas, such as food safety, medical facilities, water systems, or vector control, among others. In addition, public health authorities from the Netherlands, Morocco, and Tanzania shared case studies to showcase their practical application of these IHR requirements in their respective countries. Given its success, WHO plans to replicate similar sessions in the future to reach additional time zones and regions and cover other pressing border health-related topics, ensuring that Member States can continue benefiting from these opportunities to share knowledge and expertise.
Prediction market bets on Khamenei killing spur outrage from all sides
Prediction market users complained about unfair markets over strikes in Iran. One senator promised to introduce legislation to prevent "profiting off war."
Cook County public health grant threatened by federal funding cancellation
Grant funding for Cook County Public Health and Human Services (PHHS) is at risk after the Centers for Disease Control and Prevention (CDC) canceled millions of dollars in public health investments for Minnesota. The Public Health Infrastructure Grant awarded Cook County more than $30,000. Statewide, about $38 million in public health funding was canceled, effective...
OpenAI shares language from its contract with the Department of War
OpenAI said its contract with the Department of War prevents its technology from being used for mass domestic surveillance or autonomous weapons.
Daily habit doesn't help prevent colorectal cancer, scientists warn — and it 'comes with immediate risks'
Alabama House committee approves bill to allow public health agency to inspect jails and prisons
Many groups say the kitchens and food service areas need to be inspected to help prevent illnesses from spreading.
Trump announces attack on Iran, says US will 'destroy' its missiles
The U.S. aims to wipe out Iran's ballistic missile program, prevent it from obtaining a nuclear weapon and help its people seize control, Trump said.
Trump orders federal agencies to stop using Anthropic tech over AI safety dispute
Defense Secretary Pete Hegseth said he was designating Anthropic as a supply chain risk, a move that could prevent U.S. military vendors from working with the company.
Congress prepares for war powers resolution vote to block U.S. strikes on Iran
House Democratic Leader Hakeem Jeffries said Friday a bipartisan coalition is working to force a vote as soon as next week on a war powers resolution that would attempt to prevent any U.S. action against Iran without approval from Congress.
February 27, 2026
A new simulation shows large amounts of hydrogen in our planet’s core. Scientists report on what they found in 290-million-year-old vomit. Plus, a comedic play and a 20-year neurology study explore what we can do to prevent dementia and cognitive decline. And, a federal law aims to close the legal loophole that lets stores sell THC products from hemp.
Suspected measles case reported in Broomfield
Measles is a highly infectious but preventable disease with symptoms that can include fever, cough, runny nose and red eyes.
The US has surpassed 1,100 measles cases in two months. Expect more deaths next
The US has recorded more than 1,100 measles cases so far this year, according to data published Friday by the US Centers for Disease Control and Prevention. It’s a troubling milestone that has many in public health bracing for the worst.
Free summits on men’s substance-misuse prevention, youth mental health set for Feb. 28 in Detroit
Community leaders, mental health professionals, and public safety officials are teaming up Saturday for a double summit on men’s substance misuse prevention and youth mental health in Detroit.
Bolstering Infectious Disease Outbreak Prevention and Response in Niger and the Dominican Republic Through the America First Global Health Strategy - United States Department of State
On February 26, the United States signed bilateral health cooperation Memoranda of Understanding (MOUs) with the Dominican Republic and the Republic of Niger, reinforcing U.S. leadership in global health while advancing country ownership under the Trump Administration’s America First Global Health Strategy. In the Dominican Republic, the United States signed a five-year bilateral health cooperation […]
Scientists Are Setting Off Earthquakes. On Purpose.
At the Bedretto Underground Laboratory deep in the Swiss Alps, scientists are inducing tiny earthquakes along a natural fault zone in the hopes of understanding what can trigger—and prevent—a deadly earthquake.
Federal panel behind cancer screening recommendations hasn't met in nearly a year
The U.S. Preventive Services Task Force's meetings have stalled as Health Secretary Robert F. Kennedy Jr. has reshaped other federal advisory committees.
American heart health worsening
New statistical snapshot finds disappointing trend despite advances in treatment, ways to prevent nation’s leading cause of death.
R.I. legislators take aim at private equity in health care
The legislation would create a “transparency and early warning” system that could potentially prevent private equity from buying up R.I. hospitals in the future.
Supply Chain Spotlight: How medical distributors and health systems stay ready for late-season flu surges
On Feb. 6, 2026, the Centers for Disease Control and Prevention (CDC) reported that flu activity was "elevated" across the U.S. The CDC estimates that since the current flu season began in October...
Why Are So Many Teen Girls Still Tearing Their A.C.L.s?
For years, ligament tears have been a crisis among young athletes — even though a few simple exercises can prevent them.
States Sue to Block Trump’s ‘Anti-Science’ Vaccine Policy
Climate change helps spread vaccine-preventable diseases. But the Trump administration’s reduced vaccine schedule “throws science out the window,” and makes Americans more vulnerable to infections, state attorneys general charge in a new lawsuit.
Science is winning the war on cancer
Our podcast on science and technology. A better understanding of how cancer develops in human cells is leading to new ways to prevent it
House votes down Senate air safety legislation
The aviation safety bill would have required aircraft to carry advanced location tracking technology, which could have prevented last year’s deadly midair collision