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Haaland receives sixth Ballon d'Or nomination
Manchester City and Norway striker Erling Haaland has been named in the 30-player shortlist for the 2026 Ballon d'Or. The 26-year-old made 52 appearances across all competitions last season, scoring 38 goals and contributing nine assists, as Manchester City lifted the FA Cup and Carabao Cup. Haaland's new team-mate Ayyoub Bouaddi has also been nominated for the Men's Young Talent of the Year award.
Cambridge Entrepreneur Wins $25,000 in Business Pitch Competition
CAMBRIDGE, WI – Collaborative 523 Inc., in partnership with the Wisconsin Economic Development Corporation, has announced Jacy Eckerman as the winner of the second cohort of its Business Pitch Competition.
Former Kane Realty COO launches AI-powered real estate consulting firm
Bonner Gaylord and David Shaner co-founded Grounded Intelligence to help Triangle commercial real estate firms implement AI tools for competitive advantage.
When is the Carabao Cup draw for the fourth round?
Everything you need to know as the competition continues
Pete Davidson reveals emotional 9/11 connection to Michael Strahan: ‘You put me on your shoulders’
In a new documentary, Davidson and Strahan recall and relive the happy meeting that took place amid tragedy and pain.
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
Ask Pete Dougherty your questions about the Green Bay Packers
Pete Dougherty is taking questions as the Green Bay Packers head into the Week 1 season opener against the Minnesota Vikings in Minneapolis.
Community Partners Offer Reduced-Cost Rabies Clinic
Regional clinics are setup to support animal health ensuring pets remain protective.
I’ve already picked my National Television Awards winners - here’s who I think will be bringing home the trophies
The competition is fierce, but I know who I want to come away from the ceremony with a gong
KC Crain: Next governor must make Michigan more competitive
Our state has great strengths, but we also have major problems that the next governor will need to address.
Six decades of politics (but little government)
The first aired episode of “Star Trek,” entitled “The Man Trap,” premiered on September 8, 1966 — 60 years ago today. I’m actually editing a political science fiction issue of The Forum right now, and it’s prompted to me think a lot about the ways that Trek deals with politics and government and what it’s offered us as commentary. The @smotus report is a reader-supported publication. To support this work, please become a paid subscriber. Subscribe The original TV series ran from 1966 to 1969. It had a loyal but modest following, but the audience grew substantially with the series in syndication for years after that. The franchise developed its first motion picture in 1979, followed by five sequels, and then a whole other series of films built around the “Next Generation” series that first aired in 1987. In recent decades, several more TV series have built up around it, including the current “Strange New Worlds,” now in its fourth season. Throughout the past six decades, the franchise has offered us a good many insights into US politics and international relations, although often disguised as science fiction yarns. The original series was largely a Cold War fable, with the United Federation of Planets (a stand-in for the US) perpetually at odds with the Klingon Empire (a stand-in for the USSR). The “Let That Be Your Last Battlefield” episode (1969) posited a planet divided into two races, largely indistinguishable to outsiders, but nonetheless constituting a brutal racial hierarchy. “Patterns of Force” (1968) showed a struggling planet where the leader had attempted to construct a benevolent dictatorship — literally Nazism without bigotry — and found that authoritarianism could not exist apart from hierarchy and oppression. (Relatedly, I’d put “Star Trek VI: The Undiscovered Country,” high on a list of dad films about the end of the Cold War, near “The Hunt for Red October.”) Get 20% off for 1 year Indeed, the original series itself was something of a political statement, with a multi-racial crew running the Enterprise, a diverse and largely peaceful Federation mostly free from want and oppression, and protected by Starfleet, an armed force whose scientific mission was at least as important as its military one. Famously, when Nichelle Nichols wanted to walk away from the role of Uhura on the original series, none other than Martin Luther King, Jr. met with her and urged her to remain on the show, discussing the importance of viewers seeing an intelligent Black woman as part of the command team three centuries hence. Later series in the Trek franchise offered a good deal of political commentary on their own, but probably none as explicitly and incisively as “Deep Space Nine,” which ran from 1993 to 1999. The episodes surrounding the Dominion War, especially the “In The Pale Moonlight” (1998), showed the compromises, sacrifices, and moral rot associated with winning even a just war — probably better than any series would until “Andor” (2022-25). In “Far Beyond The Stars” (1998), Captain Benjamin Sisko is somehow transplanted to the role of a science fiction writer in 1950s New York. The writer is frequently sidelined and his ideas stolen because publishers don’t want to credit a Black writer. Several series have depicted the secretive Section 31 — an unacknowledged black ops security force operating within Starfleet. These episodes often end up using Section 31 as a foil to show the dangers of a lawless group within a lawful society, even (especially) when that group posits itself as essential for everyone else’s freedom to continue. The current “Strange New Worlds” has played with a few political themes. I found the first two seasons of this show among the best that the Trek franchise has produced in decades, but this season and the last have really been struggling for ideas. Yet one interesting thread is the idea that the diplomatic and enlightened leadership style of Captain Christopher Pike will not work in all situations. “A Quality of Mercy” (2022), which I wrote about here, puts Pike in the middle of a battle with a Romulan vessel in an alternate timeline, and finds that Pike’s conciliatory style would actually make a lengthy and deadly war more likely, while a quick and more violent approach might have prevented the war. This season’s opener, “Valles Marineris,” shows a pre-lightspeed civilization locked in a war to the death with a neighboring planet. The idea of an alliance or a federation hasn’t even occurred to them — their ship’s commander is curious but doesn’t see it as an option. For a franchise as political as “Star Trek,” one thing we almost never see is the government. We get occasional glimpses of Starfleet’s council — mostly uniformed people at a rectangular table — but almost no sense of how the Federation is governed. Are there elections? Who is in the legislature? How much power does the president have? What kind of factional divisions do they wrestle with and how? The shows and films are pretty silent on this. We’ve seen a few military tribunals within Starfleet, but little about how civilians deal with crime and injustice. With recent years seeing some of the franchise’s more interesting plot lines and casts, it seems clear that Star Trek is still full of energy and ideas. Given the erosion of American democracy and the reshuffling of the international order, there’s no shortage of material for future shows to comment on. I’m not sure we should toast to 60 more years, but cheers to a show that continues to teach us about ourselves. Share
Elvira joins “R.L. Stine’s Pumpkinhead 2” as mysterious witch — See the first look (exclusive)
The Mistress of the Dark, a.k.a. Cassandra Peterson, will play a character named...Cassandra.
Joliet Chamber: The value of being connected and why business relationships still matter
With busy schedules and countless demands competing for their attention, simply putting a networking event on the calendar isn’t always enough. People want to know that their time will be well spent.
'Guts, style and fight' - no need to panic yet
Coventry City are yet to get off the mark in this 2026-27 Premier League campaign, sitting bottom of the table with no points from the opening three games. BBC CWR fancaster Danny Finlay said Frank Lampard's side showed "guts, style and fight" at the Etihad which has convinced him they have enough to compete in the top-flight this season.
From Olympic gold to Goldman Sachs: Ryan Held takes on new challenge in high finance
Ryan Held, two-time Olympic gold medalist, transitioned from highest levels of competitive swimming to Goldman Sachs and relocated to Dallas to build his career in finance.
Daniel Farke: We want to go through
Daniel Farke will take his side away from home on Wednesday evening, facing Chelsea at Stamford Bridge in Round Three of the EFL Cup.The Whites have been a familiar opponent of the Blues in cup compet...
No public season target for Jaissle
Newcastle have forecast a range of financial scenarios, depending on where the club finish this season, but sporting director Ross Wilson maintained the German has not been set a specific target for the campaign. Chief executive David Hopkinson, though, reiterated that Newcastle's ultimate ambition is to "consistently and credibly compete" for the top honours in the long run.
Tottenham's spending means they 'should be better'
BBC Radio 5 Live's Monday Night Club has been discussing Tottenham's start to the season, with Chris Sutton asking when boss Roberto de Zerbi is going to "take responsibility" for results against a background of the amount of money spent. Spurs are in the bottom three having picked up just one point from their opening three league games, and are yet to score a goal in the competition - though they did put five past Charlton Athletic in the Carabao Cup second round. "I've not seen those comments if he has done, but he's made a fair few excuses so far this season," said former Premier League striker Sutton.
GOP’s Trump-led midterm convention comes to Dallas this week
The two-day gathering, informally dubbed “Trumpapalooza,” will put Texas at the center of the political world as it hits the homestretch of its most competitive election cycle in years.
The future of Burke Lakefront Airport could depend on who wins Ohio’s midterm elections
Mayor Justin Bibb's push to close Burke Lakefront Airport needs an act of Congress — and Ohio's competitive midterm races could determine whether that's possible.
The future of Burke Lakefront Airport could depend on who wins Ohio’s midterm elections
Mayor Justin Bibb's push to close Burke Lakefront Airport needs an act of Congress — and Ohio's competitive midterm races could determine whether that's possible.
Four Lake Norman hospitals seek approval for 3D body scanner. Only one will get it
Atrium, Duke Health, Novant and Southern Oncology compete to set up a 3D body scanner outside Charlotte.
NOAA Announces Priorities to Promote Science-Based American Seafood Dominance
The priorities serve as an operational roadmap of NOAA Fisheries’ direct support of the President's Executive order on Restoring American Seafood Competitiveness.
Read the “Nonnegotiable” petition
A coalition of Michigan rabbis and Jewish leaders is launching a petition drive aimed at Dr. Abdul El-Sayed, the Democratic Senate nominee.
Hospitals pursue deals to ensure survival as Trump's Medicaid cuts loom
Rural health systems are seeking partnership to survive, fueling a debate over competition and the rising cost of medical care.
Tennis Australia chief suggests Grand Slams cut back on best-of-5 matches
Andrew Abdo said the sport should explore shorter formats and changes to its scoring system as it competes with other sports for audiences.
Science Without Borders® Challenge 2027
Deadline: March 1, 2027 Applications are invited for the Science Without Borders® Challenge 2027. The Science Without Borders® Challenge is an international art contest that teaches students about important ocean science and conservation issues. This annual competition engages students and teachers around the world, inspiring them to be creative while raising awareness of the need to preserve, protect, and
Sigma 85mm f/1.2 DG Art Review: Sigma is the Alpha This Time
Sigma beat everyone to the punch. If you have been waiting for an f/1.2 portrait lens for E-mount or L-mount, wait no longer.
UE men’s soccer set to host Louisville
EVANSVILLE, Ind. (WEHT) — The University of Evansville men’s soccer team is gearing up to host their second ranked opponent of the season in the 22nd ranked Louisville Cardinals. The Purple Aces are still looking for their first win of the season in what has been a competitive preseason so far. UE has played some stiff […]
New Hampshire voters pick nominees as Sen. Shaheen’s exit sparks a scramble for key seats
New Hampshire primary voters are choosing candidates for Congress, governor and the state Legislature, with the retirement of U.S. Sen. Jeanne Shaheen creating the most competitive races | K-DAWN
New Hampshire voters pick nominees as Sen. Shaheen’s exit sparks a scramble for key seats
New Hampshire primary voters are choosing candidates for Congress, governor and the state Legislature, with the retirement of U.S. Sen. Jeanne Shaheen creating the most competitive races | Talk Radio 1210 WPHT
New Hampshire voters pick nominees as Sen. Shaheen’s exit sparks a scramble for key seats
New Hampshire primary voters are choosing candidates for Congress, governor and the state Legislature, with the retirement of U.S. Sen. Jeanne Shaheen creating the most competitive races | WWL
The war on Iran’s energy infrastructure creates rising political risk
When Israel targeted Tehran’s oil storage facilities in the initial days of the war launched on Feb. 28, black smoke blanketed the capital and plunged parts of the city into darkness. Roughly ten days later, strikes hit natural gas facilities at the giant South Pars field, key oil refineries, major steel plants, and petrochemical complexes, impacting thousands of workers. These attacks on vital energy and industrial assets revealed a critical dimension of the conflict: compounding an already acute domestic energy...
Health Department urges safety and preparation during heat advisory
The Nebraska Department of Health and Human Services urges residents to stay hydrated, never leave children or pet in cars and limit outdoor activity.
Champions League Is Back! TV Channels, Live Stream, Kickoff Times
The UEFA Champions League is back, and this midweek belongs entirely to Europe’s biggest club competition. With the Europa League and Conference League still waiting to begin their league phases, the Champions League takes over three days — Tuesday, Wednesday and Thursday — for a packed 18-game opening Matchday. UEFA’s official 2026-27 Champions League schedule […] The post Champions League Is Back! TV Channels, Live Stream, Kickoff Times appeared first on HEAVY.
A Weekend Full of Wins for the Cantera Rojiblanca!
The Cantera Rojiblanca faced another busy weekend of action on Matchdays 7 and 8 of the Apertura 2026, with our young players once again showing their Rojiblanco DNA and competitive spirit. Their perf...
Drew Brees replaces Maxx Crosby on SiriusXM’s ‘Let’s Go!’
The media renaissance of Drew Brees continues unabated. Not only will the former New Orleans Saints quarterback embark on his first full season in the booth alongside Adam Amin for the NFL on Fox, but the 47-year-old will also co-host SiriusXM’s Let’s Go! alongside Matthew Stafford, Jim Gray and Peter King, effectively replacing Las Vegas…
Midterm elections head into the home stretch as candidates hit Labor Day events
Candidates in several states with competitive House and Senate races are beginning the stretch run of election season with Labor Day events at festivals, union halls and parades.
How Baltimore could divide RB snaps behind Derrick Henry
Justice Hill and Rasheen Ali will compete for opportunities behind Derrick Henry
Sports Illustrated lists Seahawks as "winners" going into 2026
The Seahawks made the necessary moves in the offseason to come away as winners prior to Week 1, despite much competition existing across the NFL.
How 9/11 bonded Michael Strahan with his ‘little brother’ Pete Davidson
Michael Strahan reveals how he and Pete Davidson were connected through 9/11 in the new documentary, ‘9/11: United We Stand — 25 Years Later,’ available to stream on Hulu and Disney+.
How 9/11 bonded Michael Strahan with his ‘little brother’ Pete Davidson
The new documentary, “9/11: United We Stand — 25 Years Later,” is available to stream on Hulu and Disney+.
Sydney Sweeney and Robert Pattinson lead the standout looks on Venice Film Festival red carpet
From John Malkovich's ruff to Nina Dobrev's vintage Armani gown, there's a lot to unpack.
Derrick Henry Says Ravens Understand Urgency After Playoffs Miss
Baltimore Ravens running back Derrick Henry said the team understands the urgency to get back to competing for a Super Bowl.
Jaguar Land Rover will cut 4,000 jobs to reduce costs and compete with China
Britain’s biggest automaker said the job cuts will take place over the next two years
Jaguar Land Rover will cut 4,000 jobs to reduce costs and compete with China
Britain’s biggest automaker said the job cuts will take place over the next two years
Global Growth Fund is Re-Evaluating Flutter Entertainment’s (FLUT) Strategic Fit
Sands Capital, an investment management company, released its second-quarter 2026 investor letter for “Sands Capital Global Growth Fund”. The letter can be downloaded here. Global Growth seeks the best growth businesses worldwide, leveraging a research team that explores both developed and emerging markets for sustainable competitive advantages. In the quarter, global equities rebounded strongly, driven […]
Prince William & Kate Middleton’s ‘Fun Evening’ Includes This Reality Show
Prince William and Kate Middleton reportedly had a surprisingly relatable favorite for a quiet night at home. The royal couple apparently enjoyed settling in together for a popular reality competition...
Where Atlanta Hawks Should Finish in Loaded Eastern Conference
The Atlanta Hawks could contend for a top-four seed in 2026-27, but a dramatically reshaped Eastern Conference gives them plenty of competition.
AP Decision Notes: What to expect in New Hampshire’s state primary
WASHINGTON (AP) — Two former Republican U.S. Senators eyeing a return to Washington will compete in New Hampshire’s state primary Tuesday for a seat they’ve bot
AP Decision Notes: What to expect in New Hampshire’s state primary
Former Republican U.S. Sens. John Sununu and Scott Brown will compete in New Hampshire’s U.S. Senate primary Tuesday for the seat currently held by retiring Democratic U.S. Sen. Jeanne Shaheen.
AP Decision Notes: What to expect in New Hampshire’s state primary
Former Republican U.S. Sens. John Sununu and Scott Brown will compete in New Hampshire’s U.S. Senate primary Tuesday for the seat currently held by retiring Democratic U.S. Sen. Jeanne Shaheen.
AP Decision Notes: What to expect in New Hampshire’s state primary
Former Republican U.S. Sens. John Sununu and Scott Brown will compete in New Hampshire’s U.S. Senate primary Tuesday for the seat currently held by retiring Democratic U.S. Sen. Jeanne Shaheen.
With $100 worth of supplies, this Chula Vista teen just won a prestigious international science award
Ihan Sung, 17, won fourth place in the Regeneron International Science and Engineering Fair. Two other students from Eastlake High also competed.
CREDA poll: New Mexico’s gross receipt tax makes it hard to do business
Some developers said New Mexico’s gross receipts tax makes the state less competitive than its neighbors. They believe tax reform for new construction would go a long way in attracting new development and investment.
Commission to present long-awaited Innovation Act proposal
The European Commission will present its proposal for an EU Innovation Act on September 9, with a focus on strengthening public procurement as a driver of innovation and facilitating the use of intellectual property (IP) to secure financing.The proposal was initially meant to be published in March. No explanation has been given for the delay, but it may be linked to issues with the associated impact assessment.The Commission’s Regulatory Scrutiny Board issued a negative opinion on the draft impact assessment following its meeting on January 28, and again on February 27, according to a draft of the Innovation Act published by Agence Europe.In it, the Commission lays out the steps it has taken to address the board’s concerns, including avoiding overlap with the upcoming revision of the EU Public Procurement Directives and removing a mandatory target for EU member states to increase overall innovation procurement spending.The Innovation Act, which was included in last year’s start-up and scale-up strategy, is meant to reduce barriers to bringing innovative solutions to the market and speed up the path from research to commercialisation.Central to the initiative, according to the draft proposal, is the introduction of a harmonised EU framework for the procurement of R&D services by public buyers, including pre-commercial procurement. The plans would also introduce an EU preference in public R&D procurement.“Other leading economies in the world are investing five to eight times more in public procurement of R&D than the EU,” it notes. In Europe, the lack of harmonised rules has led to divergent practices across the bloc, legal uncertainty and limited use of joint, cross-border R&D procurement, it says.Related articlesCommission postpones European Innovation ActParliament draft report adds EU Inc safeguards to prevent fraud and regime shoppingThe text highlights a lack of clarity around the valuation and monetisation of IP as another barrier to the commercialisation of research results. Currently in the EU, IP is rarely used as collateral in financing, which restricts the growth potential of innovative firms. A key reason for this, according to the Commission, is the absence of a harmonised methodology for valuing IP.To address this issue, it plans to introduce an EU-wide IP valuation framework, a digital marketplace for commercialising IP, and a competence centre to help innovators access IP-backed finance.The issue was highlighted by a recent report by the European Union Intellectual Property Office, which referred to developing a “functional market for IP-backed finance” as a “core competitiveness imperative for the next decade,” and key to ensuring capital unlocked by other EU initiatives reaches innovative firms.The Innovation Act is one of several ways the Commission hopes to reduce fragmentation in the single market and help innovative companies to scale in Europe, complementing other initiatives such as the EU-wide corporate regime, dubbed EU Inc.The leaked draft is not the final version that will be published on September 9, according to a Commission official.
Pittsburgh Plates: Popular Bar Heading West, Health Department Closes Eatery & More
Time to satisfy your appetite for Pittsburgh's latest bar and restaurant news.
Elon Musk begins to spend money ahead of competitive midterm election
A look at spending for the midterm elections in November.
Pokémon Champions’ director vows to keep turn-based battles as single-player is ruled out
Masaaki Hoshino reflects on Champions’ launch and discusses the future of competitive Pokémon…
The percentage that builds a real business - Chicago Agent Magazine Top Coach
The best predictor of who’s going to make it is what percentage of GCI an agent puts back into the business.
Factbox-The Nine Midterm Races That Will Decide Control of the US Senate
By Andy Sullivan WASHINGTON, Sept 7 (Reuters) - Democrats need to pick up four seats from Republicans to win control of the 100-seat Senate in the midterm elections on November 3. While voters will pick candidates in 35 states, independent analysts only see nine of those races as competitive.
Chelsea working on early Alex Scott deal to avoid bidding war
Chelsea are working on an early deal to sign Bournemouth midfielder Alex Scott in a bid to avoid competition for the midfielder next summer.Bournemouth turned down a £64m offer from Chelsea during th...
Physitrack Wins Deal with Large US Healthcare System Following Competitive Process
Three-year enterprise agreement with a total contract value of approximately US$390,000 (approximately EUR 336,000) in total, subject to signing of the software services agreement.New York City, September 7, 2026Physitrack PLC (Nasdaq First North Premier Growth Market: PTRK), a global provider of d…
Jamaica takes its case for reparations for Britain's role in slavery to King Charles III
Jamaica is pushing for Britain to pay reparations for the trans-Atlantic slave trade. On Monday, the Caribbean nation will petition King Charles III to refer questions about slavery and the U.K.'s...
Jamaica takes its case for reparations for Britain's role in slavery to King Charles III
Jamaica is pushing for Britain to pay reparations for the trans-Atlantic slave trade. On Monday, the Caribbean nation will petition King Charles III to refer questions about slavery and the U.K.'s...
20th Asian Games Aichi-Nagoya 2026: Top stars in action, schedule, sports with LA28 qualifying at play
The landmark 20th Asian Games take place this month in Japan, with LA28 Olympic quota spots at play in a number of sports. Find out some of the star names competing at Aichi-Nagoya 2026 and how to watch the action.
Leeds gather momentum as Gudmundsson returns to starting XI
It has been a long wait for Leeds fans to see Gabriel Gudmundsson back in action in a competitive match for the Whites. "The process starts now, and it is going to get better and better for us," said Gudmundsson.
A2RL season 3 heads international
Watch highlights from the Abu Dhabi Autonomous Racing League's first competitive race away from its Yas Marina home
Scientists reconstructed a Wyoming forest from 56-million-year-old fossil leaves; it lost about 60% of its canopy during ancient warming and took more than 100,000 years to recover
Deep in the rock record of Wyoming, a layer of fossil leaves tells a quiet but powerful story about what happens to forests when the planet warms rapidly. About 56 million years ago, during a spike in global temperatures known as the Paleocene Eocene Thermal Maximum (PETM), a lush subtropical forest that once covered the region lost roughly 60 percent of its canopy.
Huawei launches new foldable smartphone as competition with Xiaomi, Apple heats up
Huawei launched a new version of its flagship foldable smartphone on Monday as it seeks to defend its lead in the Chinese market for premium handsets against Apple and Xiaomi , both of which are also unveiling new products.
How Burnham’s Britain can gain the edge in life sciences
Our country has historically been at the forefront of innovation. We need to bw flexible to fend off competition
Louisville football outlasted by Ole Miss in season-opening shootout
Jeff Brohm's Louisville Cardinals dropped a back-and-forth Week 1 college football game against Pete Golding's Ole Miss Rebels on Sunday in Nashville.
Doubts damp demand for business courses in the ‘Anglosphere’
Immigration policies, inflation and uncertain job markets have reduced appetite for study in the UK, US and Canada
White Sox 10, Twins 1: Mostly flightless birds on Peacock
In which the competitive portion of the season comes to an end
Rosko's Brew House wins award in national beer competition
Williamsport, Pa. — A Williamsport micro-brewery won its first national award recently at the U.S. Beer Open Championship.
The science behind the beauty business
Some of Europe’s industrial champions may be in retreat, but its cosmetics sector remains a global leader, buoyed by healthy demand, recognised brands and a reputation for innovation."The fact is, the science in cosmetics is better here in Europe than anywhere else in the world,” says Pierre Morvan, CEO of Technature, a private label cosmetics manufacturer located near Brest in France’s northwestern Brittany region. “You have to have good science in order to make the difference, and that is why we invest so much in research and innovation.”Across Europe, the beauty and skincare products sector supports an estimated 3.6 million jobs, including 265,000 employed directly in the industry, according to the Cosmetics Europe trade group.. Cosmetics production contributes an estimated €11 billion to the EU economy, and generated €30 billion in export revenue last year, a €400 million rise from 2024.Technature itself has a global footprint, supplying products for 1,500 brands in 65 countries. Its range of skin gels, facial masks, nail treatments and other products include natural ingredients and extracts derived from plants, such as seaweed, that are developed and refined through science-based analysis and testing.While industry projections point to sustained growth for the foreseeable future, driven by emerging economies and wider availability of exclusive brands that were once chiefly sold by high street retailers, the sector is not immune to the impact of geopolitics and trade wars. The Trump Administration’s tariff threats have dented cosmetics exports to the EU industry's largest overseas market. After the European Parliament approved the EU-US Turnberry Agreement in June, setting a 15% levy on many EU goods, the French Federation of Beauty Companies warned that “exports are falling sharply” and urged the EU to negotiate an opt-out for cosmetics.Technature’s CEO flags South Korea as an emerging competitor, partly due to its assertive marketing efforts. “I would have to say I am a little bit scared,” Morvan says, regarding the growth potential of the South Korean cosmetics industry. “This is why science and innovation are so important if Europe is to remain the leader.”With a workforce of 200, including biologists, chemists and other scientists, around 15% of Technature’s staff work in three research and development (R&D) labs. A similar number work in four quality control and assurance facilities, where science plays a crucial in ensuring product safety in a sector that is subject to the European Cosmetics Regulation.Educational exchange between industry and academiaIn recognition of Technature’s research and innovation, Morvan was selected as one of Brest’s ambassadors to Science Comes to Town (SCTT), a European initiative to strengthen communications and understanding between science and society. Brest is one of three coastal cities in the EU-funded programme, alongside Split (in Croatia) and Kiel (in Germany). From 7-11 September, Brest will host the EU TalentOn contest featuring 100 early-career researchers from across Europe.Morvan appreciates the value of engagement with educational and scientific institutions as well as the home community. For instance, Technature collaborates closely with university partners to enhance its in-house R&D. In addition, it invites students to its labs and sends its own researchers to local institutions. "We absolutely want the students to know what the industry is all about,” Morvan says, noting that seeing science in action can help young people “understand that they can do something real with science, to create something with what they are learning.” He says another important benefit: encouraging new generations of young people to consider a career in cosmetics.Community involvement also raises awareness about Technature and the skincare industry as a whole. “The public gains recognition of the innovative company that we are, and this is important for getting new customers,” Morvan says. One of its recent innovations — tiny, colourful cosmetic pearls that release skin moisturisers on application — was showcased at this year’s VivaTech event in Paris.Morvan holds a master's degree from the Brest Business School and studied animal production and biology in Brest at the University of Western Brittany (UBO), an SCTT partner, and at the University of Tours. He got his start in business in 2002, initially working on using seaweed as a raw material in the food industry before transitioning to cosmetics. Morvan has always been interested in connecting science and business, reflecting one the goals of SCTT to enhance public-private collaboration.The invitation to participate in SCTT was unexpected. “It was a surprise to get a call from the city of Brest saying that they wanted me on this programme,” Morvan recalls, adding that officials were drawn by his company’s R&D. “It's not only theory and science fundamentals. Our science is something that is applicable to the global market — and important for the community.”Science|Business, which connects policymakers, academics and industry through its news reporting, analysis and events, is an SCTT partner.
The core anti-Pangram constituency is phony writers
Welcome to The Closing Argument, our verdict on the news, plus everything The Argument published and appeared in this week. The Verdict, by Kelsey Piper A lot of people hate AI for drowning the internet in slop and displacing human creatives. You might think that these people would be thrilled by a program that can identify and flag AI-generated work. But many people who hate AI also hate Pangram, an impressively accurate AI detector that produces very few false positives, according to high-quality independent research. This loathing found its most recent expression in a bizarre Wired article that amplifies a wide range of false arguments from Pangram skeptics: that AI detectors are racist (they’re not) or ableist (they’re not)1 or don’t work (this one does)2. Rather than starting from the premise that it would be really valuable to have a working AI detector and scrutinizing Pangram to make sure it lives up to that promise, the article starts from the premise that Pangram obviously has bad vibes and sets out to discover why. (One answer: The CEO microwaved lunch during an interview!) Why aren’t writers who resent Pangram more eager to distinguish themselves from posters who are having ChatGPT ghostwrite all their work? There are a few different things at play, but I think one key dynamic is this: These are often the same people. A core constituency for arguments like Wired’s is “writers” who are using AI to write their posts but resent this fact being made public. They stand to lose from AI detectors because AI detectors call them out. Share When Substack announced a partnership with Pangram, a sizable fraction of the platform’s authors rose up in outrage. Some people had experience with other AI detectors that didn’t work, and some felt that AI writing ought to be encouraged — both of which are fair enough. But the fury was fueled by authors passionately insisting that Pangram kept wrongly accusing them on almost every post they published. Pangram can be wrong, especially on short passages. But in the overwhelming majority of cases where Pangram looked at a whole blog post rather than a single paragraph, the program correctly detected work as AI. Even if we can’t be 100% sure in any individual case, we can notice the trend in the aggregate. Wired quotes Sam Illingworth, a professor of critical AI literacy at Edinburgh Napier University, who said, “I don’t think [AI detectors] work. … I think that detectors are prejudiced against certain people.” This spring, he said that he used AI for research and editing; this summer he acknowledged that in addition to research and editing, he also uses it “now and then for a turn of phrase I keep.” Pangram informs us that most of his posts are 100% AI-written (some are mixed AI-and-human) and that 100% AI-written posts started appearing last year. The favorable interpretation is that, as someone whose recent work Pangram consistently mistakes for AI, Illingworth sees Pangram’s flaws firsthand. The unfavorable interpretation is that the tool’s credibility trades off against his own, because its account of who writes his posts is not consistent with his. Illingworth is not alone in insisting the detector does not work. “It’s a Monday night in late July, and I’m pasting my own Substack draft into an AI detector for the first time. Not because I’m worried. Because I’m curious. I wrote every word of it myself, the way I write everything, out loud in my head first, in a rhythm that still carries the accent of a language I learned to think in before I learned to write in this one,” begins one Substack post by an author indignant that Pangram flags her writing as AI. “That’s the part I had to sit with before I could write this.” If you, like me, have worked with AIs a lot, you won’t even need Pangram there. The author of that piece is AI. It is obviously AI! I checked 10 other posts on the blog, and they were also obviously AI! “I have spent 22 years as an award-winning author and essayist. And now this bullshit tool that learned from MY writing is going to accuse me of plagiarism,” popular Substack writer Carlyn Beccia wrote in an anti-Pangram post. “For the last and final time, AI DETECTORS DO NOT WORK.” Here’s what her writing sounded like in 2020: “Most success stories revolve around one person who believed enough in you to say — give it a try. We call these people muses, but they are so much more than that. They are the strong man giants whose shoulders we stand on so we can see the horizon. Throughout the editing process, I am sure my editor felt less like a giant of greatness and more like Atlas with the world on her shoulders.” Pangram says it was 100% human-written. (So were other articles of hers in 2020.) And here’s what it sounds like now: “And then there is the reshuffling, which sounds like paperwork until you remember that empires have always loved paperwork. The Trump regime recently moved special education oversight from the Education Department to HHS. That is not a minor bureaucratic transfer. It changes the frame.”3 Pangram says this is mostly AI. I am not convinced that Pangram is wrong. In my own experience, Pangram is very effective on long texts — if it marks a long essay as AI, the essay was either written by AI or deliberately written to sound like AI. On tweet-length or paragraph-length texts, it’s not perfectly reliable. It seems to work just as well for non-native English speakers as for native speakers. While I have seen dozens of claims of pre-2022 text returning a positive result on Pangram, I have tried repeatedly to corroborate those and have never once succeeded. To be clear, I’m absolutely not saying that complaining about Pangram suggests a writer is a cheat. There are plenty of other concerns. Most are mistakenly premised, such as the false claim that Pangram trains on work you put into it, but others are reasonable: It’s unreliable on sufficiently short text segments; it creates an internet witch-hunt mentality when there are defensible uses of AI; people who are open about their AI use are sometimes blamed, when the only people really doing something wrong are the ones who hide it; and it isn’t perfect, so a single positive result shouldn’t be taken as decisive proof of misconduct. I’m happy to concede that Pangram is imperfect and possible to over-rely on. If an author’s posts are mostly non-AI and one scans as partially AI, this could be a mistake. It’s also possible to defeat Pangram with intentional effort. If you think we need something more robust and more reliable, fine! But if you don’t like AI and don’t like Pangram, your attitude really ought to be that it’s a shame that our existing tools for AI detection are imperfect, and it’s important to invent better ones. If your stance is instead that AI is evil and so is looking for AI, then ultimately you’re contributing to the sloppification of the internet. You’re making it harder for people who write their own text to distinguish themselves, and providing cover for authors who are definitely not writing their own text. Subscribe Top stories this week, by Kobe Yank-Jacobs Commentators often worry that the decline of reading could mean the decline of liberal democracy — but deliberative governance actually predated widespread literacy. This week, Maibritt Henkel pointed out that many liberal cultures thrive on a culture of raucous, interactive debate, which can happen in-person as easily, if not more so, than in text. Read on, dear reader, to learn more. It may actually cheer you up: [ ](https://www.theargumentmag.com/p/reading-wont-save-liberalism) [ Reading won’t save liberalism ](https://www.theargumentmag.com/p/reading-wont-save-liberalism) Maibritt Henkel · Sep 1 [ Read full story ](https://www.theargumentmag.com/p/reading-wont-save-liberalism) It used to be bad to downplay climate change (if we mean denying its reality). Today, it’s actually good to downplay climate change (if we mean keeping the issue out of political fights so we can make real progress). This counterintuitive view is called “climate hushing,” and contributor Alex Trembath argued that it’s the key to enacting good policy going forward. Get up to speed on the latest in climate politics: [ ](https://www.theargumentmag.com/p/we-wont-stop-climate-change-by-talking) [ We won’t stop climate change by talking about it ](https://www.theargumentmag.com/p/we-wont-stop-climate-change-by-talking) Alex Trembath · Sep 2 [ Read full story ](https://www.theargumentmag.com/p/we-wont-stop-climate-change-by-talking) Canada’s Prime Minister Mark Carney is standing up for the forces of liberalism against Donald Trump’s assault on our closest ally. So, why is one prominent left-wing commenter attacking Carney? Columnist Matthew Yglesias explains: [ ](https://www.theargumentmag.com/p/when-economic-liberty-means-central) [ When "economic liberty" means central planning ](https://www.theargumentmag.com/p/when-economic-liberty-means-central) Matthew Yglesias · Aug 31 [ Read full story ](https://www.theargumentmag.com/p/when-economic-liberty-means-central) 🌟Abundance Wins of the Week🌟 Shout out to my home state of California, whose legislature passed two housing bills this week. One requires a housing density minimum in transit-oriented areas of the state’s most transit-rich cities (Los Angeles, Sacramento, San Francisco, Oakland, San Jose, San Diego, and Long Beach). Another bill closes two common loopholes used by third parties to delay housing projects, including an opportunity to challenge maps of a given lot created by the developer after a project has been approved. Shout out to our big-state rival, Texas, where pro-housing SB 785 took effect this week. The new state law requires municipalities to have at least one district permitted for manufactured housing without a special permit. This will promote zoning changes in 44% of municipalities. The company Fervo Energy signed a deal with Google for what is set to be the world’s largest enhanced geothermal facility, proving a technology can work at a scale that could be crucial to a decarbonized, energy-abundant economy. Share Worth watching… This week, forecasting legend Nate Silver joined Jerusalem, Matt, and Jeremiah on a crowded episode of the pod. It was a party. And speaking of parties, our round table debated the factional lines within the Democratic Party: Is it possible to be center-left and also anti-establishment? Watch or listen to find out: The Rio Grande Valley in Texas is one of the areas that swung hardest toward Trump in 2024, but musician Bobby Pulido is running to flip it back. Right now, The Argument/Split Ticket’s model has him running 1.1 points behind his Republican opponent in a district Trump won by 18 points. Tune in to find out how he differs from national Democrats and what he thinks he can to do win this seat. On Thursday, Bernie Sanders was among the first politicians to call for a ban on superintelligence. My guest this week, Andrea Miotti, has been lobbying to ban superintelligence for several years, most recently in the U.K., U.S., and Canada. I asked him how he gets legislators to take speculative risks seriously, and we dug into what plans might look like to actually pass a ban. Listen to learn more: What’s News with The Argument The Argument recommends, by Kobe Yank-Jacobs If we ever lose track of Justin Zuckerman, I’ll have the team split up and check all the movie theaters in the city. I’m shocked (and a little jealous) at how often he gets out to see good cinema. This week, he brings us It Ends, a “horror-ish movie,” which he described as a “Gen Z Waiting for Godot.” I was intrigued before he added that it was “funny, dark and existential” — at which point I was fully locked in. I guess I also had existential themes on the mind this week. One morning, a single line from a poem I read long ago just came to me: “Is death a stretch of time in which a life is just a flash?” The poem is called “From 20,000 Feet” by Heather McHugh. I suggest the version in The Vintage Book of Contemporary American Poetry, which, by tradition, my best friend and I always bring backpacking, extra weight be damned. We’ll stay thematically dark for just one more rec from senior editor John Robert Thomason, whose upcoming trip to Baltimore reminded him to suggest Michael Clune’s memoir White Out (about being addicted to heroin in Baltimore in the 1990s). Ben Lerner’s blurb called it _“_Disturbing, brilliant, hilarious—it’s as if Proust had written Jesus’ Son.” John told me this “seems accurate, with the caveat that I’ve never read Proust.” I, personally, have also shelved Proust until retirement. At this point, I was a little concerned for the team since all of us tossed out such psychologically grim material — maybe we’re all down about the end of summer — but thankfully, at least a few of us were into more upbeat selections. Milan Singh recommended Made In’s 5-quart stainless clad saucier, suggesting he had some fun in the kitchen. Jeremiah Johnson asked if he could recommend yet more Carly Rae Jepsen. Once denied, he offered up Game Changer instead_,_ calling it “the most wildly creative game show, maybe in the entire history of the genre.” Eli Richman mentioned _Lucky, “_a B-tier show with an A-tier cast and an S-tier theme song.” I suppose he was recommending the song, Horns of a Bull. Still, despite these cheerier recs, I couldn’t help but be concerned that we were subconsciously worried about racing toward summer’s end — the end of swim trunks and splashing around. Then a message landed reminding me of the three-day weekend to come. A whole extra day for sunshine. One more swim in the lake. I was grateful this called to mind yet another line from a poem, one by Mary Oliver, the patron saint of every gorgeous summer day (and about whom a documentary is now out). Speaking to God in the poem “Thirst,” she wrote: grant me, in your mercy,a little more time. Love for the earthand love for you are having such a longconversation in my heart. We have merch! We have quarter-zips, keychains, hats, and stickers. Each one is a great conversation starter in its own way. Buy them here. Subscribe More to read: [ The Opening Argument ](https://www.theargumentmag.com/p/seeing-like-an-elite)[ Seeing like an elite ](https://www.theargumentmag.com/p/seeing-like-an-elite) Kobe Yank-Jacobs · Sep 4 What do Americans hear when they watch Sen. Bernie Sanders or Vice President JD Vance rail against the elite? Are they thinking of right-wing tech billionaires? Imperious college professors? Liberal magazine writers? [ Read full story ](https://www.theargumentmag.com/p/seeing-like-an-elite) [ The Weekly Scroll ](https://www.theargumentmag.com/p/god-is-back-on-the-timeline)[ God is back on the timeline ](https://www.theargumentmag.com/p/god-is-back-on-the-timeline) Jeremiah Johnson · Sep 5 This week, we’re talking about Substack’s new religious debates, the continuing MAGA influencer scandal, how to retire from YouTube, and aura battles. [ Read full story ](https://www.theargumentmag.com/p/god-is-back-on-the-timeline) 1 This was a legitimate thing to worry about, but doesn’t seem to be a problem given the actual technology: Marijke Van Vlasselaer, Filip Van Droogenbroeck, and Bram Spruyt’s 2026 paper looks at whether Pangram is less accurate when evaluating the work of non-native speakers of English. It isn’t. That’s because Pangram isn’t really looking at how “unusual” a piece of writing is but whether it has the characteristic patterns of LLMs. The Wired article makes an odd gesture at a different Pangram-is-racist argument. There were several controversies this summer during which upcoming books were canceled after being discovered to be AI-written: “The three novels mentioned earlier — Shy Girl, Daggermouth, and Call Me, easily publishing’s biggest AI-detection scandals — were all written by writers of color.” But come on! As Zvi Mowshowitz put it: “They were not primarily written by people of color. They were primarily written by AIs.” That’s the whole problem! And as my colleague Jeremiah Johnson recently observed with respect to Cambridge’s Arday scandal, a community being unwilling to call out fraud if it’s perpetuated by people of color is not an anti-racist tendency; it is ultimately quite racist. 2 Many non-Pangram detectors don’t work, but many possible airplane designs also don’t work, and no one considers this a general argument against aviation; the thing that matters is whether any detection works. 3 The phrase “empires have always loved” mysteriously became all the rage in the last few years. See here, here, here, here and here. Before 2025, the only use of that phrase I have been able to find is a single Tweet. The logic of the sentence, too, is incoherent in an AI-characteristic way. “...sounds like paperwork, until you remember that empires have always loved paperwork”? Does remembering that make it sound less like paperwork? It’s a craft-ful sentence, but what is it actually saying??
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