SCROLL NEWS / DISCOVERY
Search headlines
Find the stories shaping the conversation.
Results for " beyond " 1,848 found 🔀 AI-powered Shuffle
SPECIAL REPORT: Tough Business
A string of vacant restaurant buildings shows that many restaurants in the region are struggling — and several are closing By Stefan Yablonski [caption id=attachment_11132 align=alignright width=401] Smokey Bones Bar & Fire Grill on Route 31 in Clay closed its doors in April. It had been in operation since at least 2008.[/caption] By their nature, most restaurants have a limited life. An astonishing 60% go out of business within three years of opening, largely due to fundamental flaws in the planning of the operation. But even restaurants that experience years of success almost always face eventual closure. The restaurant business is very hard and because of both personal factors and external factors beyond anyone’s control, restaurants don’t last forever. For many restaurants, age is a big factor, according to Kenneth Walsleben, professor of practice, entrepreneurship and emerging enterprises at Syracuse University. “The owners have been at it for 20 or 25 years, if not longer, they want some time to themselves,” he said. Such was the case for Jocko’s Famous Ritz Diner in Oswego. Jocko Reitz bought the building in the late 1970s from Robert Shapiro. However, when he stepped away from the business, it eventually closed. [caption id=attachment_11142 align=alignright width=402] For nearly 80 years, Vona’s Restaurant passed through three generations of family in Oswego. It closed its doors on Dec. 31, 2025.[/caption] For nearly 80 years, Vona’s passed through three generations of family in Oswego. Vona’s Restaurant officially closed its doors on Dec. 31, 2025, when no family member wanted to take over. It is on the market. The Ruby Tuesday in Oswego operated for about two decades before permanently closing in April 2026. The restaurant faced multiple temporary health department closures in 2024 and 2025 due to persistent fruit fly and foundation pest issues. Management posted a final closure notice on the doors in mid-April 2026 and the building was put up for sale. The same pattern has been happening in Onondaga County. The big building once used by Smokey Bones Bar & Fire Grill on Route 31 in Clay remains empty, more than six months after the restaurant closed its doors in April. It had been in operation since at least 2008. [caption id=attachment_11130 align=alignright width=401] Ruby Tuesday in Oswego operated for about two decades before permanently closing in April 2026.[/caption] Just down the road from Smokey Bones, the popular Outback Steakhouse closed in August 2024. Another restaurant took its place, La Cocina Mexican Restaurant, but it closed shortly after. The building sits empty. Other very popular restaurants in the northern suburbs of Syracuse have recently closed. Among them, Fireside by the River in Baldwinsville and Primo Nestico’s Bistro Bar in North Syracuse. “I haven’t really paid attention to the Syracuse area. There has always been some turnover, but there probably has never been a tougher time to be a restauranter than now. It’s just brutal,” Walsleben said. In the first year, roughly 20% to 25% of restaurants close or change hands, according to the National Restaurant Association. [caption id=attachment_11122 align=alignright width=401] Outback Steakhouse closed in August 2024. Another restaurant took its place, La Cocina Mexican Restaurant, but it closed shortly after. The building sits empty.[/caption] “Depending on what statistics you look at, you’ll find that any business has a high mortality rate in the first year. That is just the nature of entrepreneurship,” Walsleben said. “There are certain ones that are getting hit hard while others are more fruitful. “And when you look at the restaurant industry you have to factor in labor which is a large part — typically a third of your expenses — and those costs are going up. And there is always turnover which means investing money to train people. Then you’ve got food costs, which is also a third of the typical restaurant budget. Since the pandemic labor has gone up 41%, food costs have gone up 35%. That’s a big tight squeeze righty there. That’s two-thirds of your budget that has gone up 35% to 40% in the last few years. And then the only way you can make that work is to raise the prices.” The National Restaurant Association reports menu prices are up 36% since February of 2020. In a survey released by the association, more than eight in 10 restaurant owners reported that their food, beverage and labor costs are now higher than before the pandemic. You have to deal with the reality of are the customers willing to pay for that? Walsleben added. Restaurants historically have very thin margins; their profit margin is about 5%. “You have a third that goes into food, a third that goes into labor and about 28%, 29% that goes into everything else — overhead, insurance etc. So that brings you down to your 5% leftover,” he said. “Everything is going up. Customer expectations are going up and people aren’t going to spend that much more. So, you have a tight squeeze here,” Walsleben continued. “Restaurants who use delivery apps, they pay a fee to those guys. Those guys don’t work for free. So, you can kind of see where the squeeze comes from.” Stuck in the middle There are pockets of opportunity; the two extremes of the market can make a profit. But the middle gets squeezed out. “If you are a low-end fast-food kind of place, there is room for that. People have changed their budgets. They are still going out, but they are not spending more,” according to Walsleben. “The high end remains positive. If you have a restaurant that brings a specific experience … a great food product or you are catering to high end customers who aren’t so budget conscious, those patrons are going to expect a high-end experience. They expect excellent food every time. They are expecting excellent service. If you can meet those expectations there is room for you at the top. It’s just the guys in the middle are getting the squeeze from both ends. Tough competition, customer expectations, costs are up. Menu items, you can’t raise the prices as much as you need to. That is why you are seeing a lot of restaurants baling out.” The ones that can adapt quickly are the ones who are doing OK. “Success is heavily dependent on the strength of a restaurant’s concept development and the planning of its execution. Eventually things aren’t always new. Things change. So, if you are in the restaurant business you have got to change your menu — keep things new, fresh and update your meals. It is very fickle industry. One year carbs are out, the next year berries are out. Everybody’s diet changes — constantly chasing the latest phase. You have got to adjust your menu and move with those modifications. If you have a static menu that you have used the last couple years that hasn’t changed except for the pricing, you’ve got a problem,” he said. A lot of times these buildings are singular purpose, he added. “You have a commercially viable kitchen and you got a seating area. There is not a lot of other businesses that cater to that type of a layout. So, it’s pretty common to see another restaurant slide in,” he said. One of the things a banker learns early on is you don’t lend money to restaurants … because they fail so quickly. It is very hard to predict who the winners will be. So, if you are a restaurant in addition to all the other challenges, it is very difficult to get loans, according to Walsleben. “You might work really well in the kitchen. But that doesn’t mean you are a great businessperson,” he said. “Restaurants can fail because the owner didn’t know how to manage things properly. There are a lot of challenges. “There is opportunity at the high end and the low end. But in the middle, that’s the death valley. There are just so many things working against you. You really need to have something that will pull people in and continue to pull people in because you to constantly have to change. Think about a theme and a product that is unique to the area people don’t travel that far these days you have to be able to deliver it in an innovative fashion and keep updating to keep people coming in the door.” Out of Business? How Fast? Do nine out of 10 restaurants fail in their first year, as commonly claimed? No. Survival analysis of 1.9 million longitudinal microdata for 81,000 full-service restaurants in a 20-year U.S. Bureau of Labor Statistics non public census of business establishments in the western US shows that only 17% of independently owned full-service restaurant startups failed in their first year, compared with 19% for all other service-providing startups, according to ResearchGate. The median lifespan of restaurants is about 4.5 years, slightly longer than that of other service businesses (4.25 years). However, the median lifespan of a restaurant startup with 5 or fewer employees is 3.75 years, slightly shorter than that of other service businesses of the same startup size (4.0 years). What Makes a Restaurant Successful? Opening and maintaining a successful restaurant is not as easy as creating a great menu and serving excellent food. It takes more than that, according to local restaurant owners who have been in business for decades in the region. They all agree that there are some guidelines to running a successful restaurant. • Quality food: Successful restaurants know exactly what they serve and who they serve it to. Delivering the same great taste every single time builds loyal customers. • Smooth operations: Friendly greetings and attentive staff make guests feel welcome from the moment they walk in. Hiring staff for personality and training for skill ensures reliable, caring service. • Smart marketing: Exceptional food and experiences naturally get people talking and sharing online. Word of mouth can help entice customers. Consistent social media and targeted advertising brings in new and repeat guests also. The menu is what keeps patrons coming back to Mimi’s Diner in Fulton, located at 201 N. Second St. “We locally source our produce and our meats. Our chicken and biscuits is a popular, popular special,” said Richard Tagliareni, the third-generation owner and general manager. “It’s all homemade. We have consistently served quality food.” His grandfather started the business more than 55 years ago. Mimi’s is engrained in the community. They cater to the community and are very involved in everything from the schools to local events. The first Mimi’s Drive-In opened in Mexico. Then a second in Oswego and then Fulton. Fulton’s Mimi’s is the only one left. “The last couple of weeks have been kind of slower than normal. October is usually a busier month for us People will start coming back around again. Also, the price of gas is affecting some things,” Tagliareni added. “We try to keep our prices in line. You go out to eat, you’re going to spend about a hundred bucks or so for two people for dinner. You come here to Mimi’s you are probably for two people for dinner it’s between $50 and $60. We are trying to keep our prices in line. We did have to increase our prices a little bit but things are looking OK.” For the Press Box, 29 E. First St., Oswego, it’s also about great food and a family atmosphere. “Our sports bar and restaurant was established in 1984,” said Alison Canale Scanlon, manager. “I think putting the time into everything makes a big difference and treating people like family when they walk into your restaurant. That’s how we have always operated since 1984.” “It’s the family oriented aspect,” she added. “Consistency, quality and presentation of our food — that’s the secret to a successful restaurant. We try to be very consistent with it. We treat people like family when they come in; because we know how we want to be treated when we go to a restaurant. We treat people the same or better.”
Retiring from Farming
Start now to ensure your farm passes to the next generation Deborah Jeanne Post [caption id=attachment_11062 align=alignright width=405] Adam C. Howell, outreach director at Cornell’s NY FarmNet: “Retirement from farming is atypical planning,” he says.[/caption] Roughly 70% of family-owned farms will transfer ownership withing the next two decades, according to data from to the USDA census. Only 30% of those will remain in the family. The number of farms in New York is shrinking as the size of farms increases. In other words, there are fewer farms in the state, but they’re much larger. This is why succession planning is so important for family farms. A farm represents not only a way to make a living but a legacy and family tradition. Many families want to preserve the small farm segment of agriculture and the values it represents. Passing the family farm to the next generation can’t be left to chance. And it shouldn’t be left for “the kids to figure out” after the older generation dies. Succession planning in agriculture isn’t like other types of business retirement planning or personal final planning. “Retirement from farming is atypical planning,” said Adam C. Howell, outreach director at Cornell’s NY FarmNet. “Most farmers, their assets and the way they live and survive in retirement is tied up in the equity in the farm. Those conversations must take place a lot earlier than they think. They’re dealing with something asset-heavy that may require a trust and tax planning.” NY FarmNet offers farmers free, confidential consultation services regarding financial and business management, and family, and mental health support for farmers in New York state. It’s a program of Cornell University in Ithaca. Howell urges farmers to begin the conversation early. Most family farms are run by generations with the oldest generation most involved and typically with fewer of the middle-aged adults and young adults involved. Some of the younger generation may have off-farm jobs and not live on the homestead. “Different people have different expectations on their legacy,” Howell said. “Intergenerational conflict and discussions can be difficult. It may be good to check with NY FarmNet or Ag Mediation to help mediate these conversations with a third party. A lot of farms have broken up because people can’t decide how to divide things.” New York State Agricultural Mediation Program is a USDA‑certified, free or low‑cost service for farmers. Fair is not always equal. A sole owner simply stating that he wants to divide things equally among his children may leave one-quarter of the farm operation to an adult child who moved away and hasn’t sat in a tractor for decades. The three adult children who have toiled on the farm for 30 years may need to buy out the fourth, non-farming sibling but cannot because all of their money is tied up in the equipment, land and stock that supports their livelihood. Their payrate may not allow them to set aside much to buy out the non-farming sibling. As a result, they may need to sell parts of the farm off in order to keep it. However, doing so may limit their ability to sufficiently support their families. The farm owner may need to bequeath more assets to the farming siblings because their efforts have kept the farm going and without those assets and their work, the farm will cease operations. Howell advises seeking professional help on tax and legal issues. Without it, families can be exposed to expensive problems and infighting. A third-party expert can help farm families navigate what is truly fair in the family’s succession plans. Beyond the practical aspects of inheritance, succession also relies upon planning who will operate the farm and how. “I think it’s important that farmers understand the means and methods of farming are always changing,” Howell said. For example, many young adult farmers earn a degree at a school such as Cornell, SUNY Cobleskill or Morrisville, work on a different farm for a while and then return to their family farm with big ideas on how to improve the farm — if only their dad and uncles will agree. Intergenerational conflict is often centered on newer ideas such agritourism, online marketing and shipping goods. “It causes conflict,” Howell said. “A lot of it comes down to communication and respect within the family. If no one in the family wants to take on farming, what we’ll see is older farmers start to help trusted managers buy into the farm.” The middle-aged generation, now in their 40s and 50s, often struggle with wresting the helm from their parents. Howell said that many older farmers don’t discuss with their grown children their vital business information such as vendors, ordering supplies, pricing, recordkeeping and farm planning. They even claim that “the kids” aren’t ready yet. These gaps in cross-training may cause significant problems even before the older generation dies, if there’s an illness or injury. Howell urges farmers to document these processes and cross-train others on the farm how to handle these areas “to make sure if one person is incapacitated, the entire operation is not at risk,” he said. Mark Modzeleski, financial adviser, financial planner and president at Legacy Wealth Advisors of NY in Syracuse, advises families to talk sooner than later about who should be operating the farm. “Someone is driving the farm,” he said. “Have you decided who? Be honest when you have that conversation. Who do they turn to when there’s a question? Or who has the potential to be leaders?” Planning for leadership continuity is vital. Unfortunately, talking like this can become fraught with emotions if it’s only the family involved. Modzeleski advised finding a third party who can help drive the conversation. “Invite the right people to the conversation who can get you from point A to point B,” he said. “This is a marathon, not a sprint.” It may take sitting down a few times with an estate planning attorney who specializes in farm transition, along with a tax professional and others who can help moderate and plan. Family members, owners and possibly, integral farm managers should attend the meetings. “Figure out what you want your legacy to be,” Modzeleski added.
Web telescope spots first changing water clouds beyond our solar system
Partly cloudy, light-years away.
Ballard Partners expands global alliance with Dubai’s Farrant Group
'Together, we will give our clients seamless, coordinated counsel from Washington to the Gulf and beyond.'
NVIDIA and Danaher are working to link AI with lab experiments. The initial work focuses on select instruments.
Danaher is working to combine lab instruments, automation, software and data with NVIDIA computing and AI; work could extend beyond select instruments.
Centene CEO sees health care’s biggest AI opportunity beyond automation
Sarah London argues that AI’s greatest potential lies not in streamlining billing and paperwork, but in expanding access to care and reducing health care costs.
Doctors may be getting childhood obesity wrong, new research suggests
A Lancet Commission definition of clinical obesity cuts pediatric rates sharply by requiring evidence of health complications beyond body mass index.
In Minnesota's Senate race, the friendliest microphones can come with the biggest headaches.
As Peggy Flanagan and Michele Tafoya navigate podcasts and partisan media, their experiences reveal the opportunities — and unexpected liabilities — of campaigning beyond traditional journalism.
Business Briefcase: Sherry Dental & Wellness in Business Spotlight
SHENANDOAH — Sherry Dental and Wellness, 10 S. Bower St., is featured in the most recent Schuylkill Chamber of Commerce Business Spotlight, according to the chamber’s Anthony Merchlinsky. At Sherry Dental, “dentistry goes far beyond simply …
Opinion: How Illinois’ treasurer is using public money to spur new housing
Michael Frerichs' office might not be the first that comes to mind on housing, but he says he's trying to go beyond the traditional mold.
Beyond Wellness opens in Rogers
Health services company Beyond Wellness recently opened its first Northwest Arkansas location in Rogers. It’s the company’s fourth Arkansas clinic. The new clinic at 4100 W. Oak St. is in...
New definition of obesity looks beyond BMI and considers health impacts
Murdoch Children's Research Insitute pediatrician Dr. Danielle Longmore discusses a new global childhood obesity definition from the Murdoch Children's Research Institute that looks beyond BMI to include health impacts.
Houston gas prices fall as hurricanes, global tensions cloud outlook
Houston gas prices fell 5.8 cents this week, but hurricanes and global politics could keep fuel costs volatile in Texas and beyond.
Varying Water Clouds Detected Beyond The Solar System For The First Time – And They’re Not Around A Planet
Just a few times larger than Jupiter, with water clouds? It sounds like WISE 0855 is applying for honorary planet status.
List of DVD release dates for Oct. 13 and beyond
Following is a partial schedule of coming movies on DVD. Release dates are subject to change: OCTOBER 13: DTF St. Louis 16: Finding Emily 20: Masters of the Universe 20:
Discover the latest science on probiotics for active lifestyles
Sports nutrition is moving beyond elite performance. Discover how science-backed probiotics and postbiotics can support gut health, immunity, mental wellbeing and recovery across active lifestyles
Beyond Buzzwords: How Sutter Leaders Create Healthcare’s Blueprint
By Matthew Murphy, Vitals contributor What does meaningful transformation look like inside a healthcare system, and what lessons can it offer the rest of the industry? In a series of recent podcast conversations, Sutter Health leaders shared how they’re tackling some of healthcare’s biggest challenges, turning new ideas into action and creating a blueprint for […]
3 Bold Takes for SEC Basketball in 2026-27
With the 2026-27 college basketball season just under a month away, it's time to take a glimpse of the future and look beyond the standard expectations. SEC Basketball is full of established stars, true contenders, and teams capable of exceeding expectations. 3 Bold Takes for SEC Basketball in 2026-27 The question remains: which teams can …
World-famous science educator Bill Nye believes in Titans: ‘You're going to change the world’
As part of Cal State Fullerton's "Beyond the Conversation" series, Bill Nye encouraged students to embrace their curiosity and critical thinking skills.
Ellen Anthony’s care goes above and beyond
Ellen Anthony’s reputation precedes her at ECU Health Edgecombe Hospital, and for good reason. Read more about a valued team member.
Business Beyond the Beach | Priscila Hawthorne of The Maximum Life
Getting your Trinity Audio player ready... 🎙 Welcome to the Business Beyond the Beach Talk Show! The Miami Beach Chamber of Commerce is proud to present Business Beyond the Beach, the exclusive Chamber talk show created in partnership with Miami’s Community Newspapers. This series highlights the stories of Miami Beach Chamber members making an impact […]
Beyond Takedowns: Disrupting the Business of Counterfeiting
A brand protection program can remove thousands of infringing listings and still leave the business behind them largely intact.
Banijay Execs Tout Global Entertainment Ambitions Following All3Media Merger
CANNES, France — Banijay Entertainment may be the world’s largest independent television production company, but its top executives say the recently merged entertainment powerhouse has ambitions that extend far beyond making television shows. “We are an entertainment company,” CEO Marco Bassetti said Oct. 12 during a keynote discussion at MIPCOM Cannes. “We aren’t anymore just … Continue reading "Banijay Execs Tout Global Entertainment Ambitions Following All3Media Merger"
FOX 61
News for Connecticut, the Northeast & beyond -- including weather, traffic, sports, and exclusive original content. The YouTube home of FOX61 in Connecticut.
New ceratiq® Science Expands Skin Health Benefits to Include Sensitive Skin and Dermal Density
/PRNewswire/ -- PLT Health Solutions, Inc. today announced new clinical research on ceratiq® Phytoceramides that expand the ingredient's benefits beyond...
Beyond November: Business faces a more interventionist Washington post-midterms
In a Trump-dominated Washington, Congress ceded much of its power and relevance.
UF Health now runs hospitals from Gainesville to St. Augustine. Experts disagree on what it means for patients
Nonprofit healthcare system UF Health opened a 99-bed hospital in northern St. Johns County Sept. 22, about 60 miles from its home campus in Gainesville.UF Health Durbin Park Hospital is the newest hospital in a system that has grown well beyond UF Health Shands Hospital, its first facility. Before the new addition, the UF Health hospital system had six licensed hospitals, about 2,900 beds, more than 280 physician practices and more than 27,000 employees, generating more than $6.5 billion in annual net revenue, according to a UF Health fact sheet for fiscal year 2025-26.
How to take care of your knees in your 20s, 30s, 40s and beyond
The latest science suggests knees are more resilient than you think.
Scientists had coffee drinkers quit for two weeks. One result stood out
Quitting coffee led to an unexpected change in the body that went beyond caffeine.
BUSINESS BRIEFS October 12, 2026: Business news in the Berkshires and beyond
Business news from Berkshire Opera Festival, The Mahaiwe, Berkshire Music Schoo’, Berkshire HorseWorks, and more
Microsoft Is Taking AI Beyond the Data Center, But Its Surface Business Is Just a Small Piece of the Pie
The tech giant's latest Nvidia-powered Surface devices add another dimension to its growth strategy as shares trade near all-time highs.
Microsoft Is Taking AI Beyond the Data Center, But Its Surface Business Is Just a Small Piece of the Pie
The tech giant's latest Nvidia-powered Surface devices add another dimension to its growth strategy as shares trade near all-time highs.
Microsoft Is Taking AI Beyond the Data Center, But Its Surface Business Is Just a Small Piece of the Pie
The tech giant's latest Nvidia-powered Surface devices add another dimension to its growth strategy as shares trade near all-time highs.
Maria Lekkakos and Marc Harris Build Beyond the Beauty Business
Maria Lekkakos and Marc Harris expand from salons and skincare into Wenham real estate, wine, and their next shared ventures.
Cardi B Turns 34 After Showing Her Four Kids a Life Beyond Luxury: ‘It's Not Always Disney’
Cardi B turns 34 on October 11, marking her first birthday as a mother of four. The rapper shares Kulture, 8, Wave, 5, and Blossom, ... Read More
Analysis | Democrats are running on a scant agenda. Do they need more?
They lack a specific plan for governing, beyond turning back Trump and holding him accountable.
One income, two retirements: How couples can protect their future
Single-earner families should look beyond today’s budget and consider retirement savings, emergency funding, workforce reentry, and future Social Security benefits.
Beyond Ideological Blocs: The ICDPP’s New Intercontinental Political Dialogue
Insights from an Interview with Chung Eui-yong on the Origins, Principles, and Future of the ICDPP
Informanté on Instagram: "Namibia urged to harness growing space science opportunities Staff Reporter NAMIBIA is positioning itself to benefit from the growing space economy through new satellite infrastructure, proposed legislation and expanded education and training opportunities, with young people urged to pursue science, technology, engineering and mathematics (STEM) careers. This was said by Dr Lisho Mundia, Deputy Executive Director for the Department of Higher Education, Training, Research and Innovation, who represented Education Minister Sanet Steenkamp at the official opening of World Space Week Namibia 2026 at the Windhoek High School Stadium on Monday. This year’s World Spac
1 likes, 0 comments - informante_news on October 10, 2026: "Namibia urged to harness growing space science opportunities Staff Reporter NAMIBIA is positioning itself to benefit from the growing space economy through new satellite infrastructure, proposed legislation and expanded education and training opportunities, with young people urged to pursue science, technology, engineering and mathematics (STEM) careers. This was said by Dr Lisho Mundia, Deputy Executive Director for the Department of Higher Education, Training, Research and Innovation, who represented Education Minister Sanet Steenkamp at the official opening of World Space Week Namibia 2026 at the Windhoek High School Stadium on Monday. This year’s World Space Week is being held under the theme “Rocket Revolution”, reflecting the transformation of space technology from the first human-made satellite launched in 1957 to modern spacecraft, satellites, space stations and missions beyond Earth. Full story: https://informante.web.na/?p=401904 Photo: National Commission on Research, Science and Technology - (NCRST)".
Laura Alder: Duke Health Announces Continuing Education Conference on Bispecifics, ADCs, and Beyond
Laura Alder: Duke Health Announces Continuing Education Conference on Bispecifics, ADCs, and Beyond / bispecifics, cancer, Charlie Rudin, Duke Health, Laura
HSBC’s Synopsys Upgrade Bets on a Business Model Shift. Can It Justify $700?
HSBC upgraded Synopsys Inc. (NASDAQ:SNPS) to Buy from Hold on September 25 and raised its price target from $490 to $700, implying a multiple of nearly 35 times HSBC’s fiscal 2027 EPS estimates. According to analyst Frank Lee, the company is evolving beyond its traditional slow-growth software profile as its licensing-plus-royalty model and agentic AI […]
Brian Schottenheimer Must Answer for More Than the Offense
Brian Schottenheimer faces scrutiny after the Cowboys’ loss to Tampa Bay exposed problems that extend beyond the offense and into his entire team.
In a heartbeat: What mammograms can reveal about your health beyond breast cancer
As the first and best line of defense when it comes to early detection of breast cancer, mammograms boast a sensitivity of about 87%, according to the Breast Cancer Surveillance Consortium. But what if their utility to women’s health didn’t end there? Bethani Hahn, section chief of breast imaging at
Amazon Small Business Event: Empowering the Next Generation and Scaling Service-Based Entrepreneurs
Join Hera Hub and Amazon for a hands-on workshop designed to help aspiring entrepreneurs and established service-based business owners bring new products to life. Amazon experts and small business owners will provide practical guidance, useful tools, and actionable next steps to launch a product and build a business with Amazon. This event is free but space is limited to 60 participants and will fill up. The event includes a light breakfast and lunch. Participants will choose from two specialized tracks based on their goals and stage of business. TRACK 1: NEXT GENERATION From Product Idea to Online Store Designed for aspiring young entrepreneurs, from junior high students through college and beyond, who have a product idea or want to explore the world of e-commerce. Amazon small business owners and Amazon experts will review topics such as: • How to develop and refine a product idea • How to set up and sell products on Amazon • What to consider when pricing, marketing, and fulfilling orders • Practical next steps for moving from idea to launch Whether participants already have a product in mind or are simply curious about entrepreneurship, this track will help them see what is possible and give them a roadmap to get started. TRACK 2: SERVICE EXPANSION Turn Your Expertise Into a Product Designed for consultants, coaches, speakers, creatives, and other service-based entrepreneurs who want to expand beyond trading time for money. Participants will explore how to transform their knowledge and expertise into tangible products such as: • Books and workbooks • Journals and planners • Card decks • Educational tools and resources Amazon small business owners will share how they identified viable product opportunities and created a product that can generate revenue beyond their one-on-one services. An Amazon expert will also review self-publishing and other ways to build a business with Amazon. By the end of the workshop, participants will leave with greater clarity, practical guidance, and a tangible next step toward launching or expanding their product-based business. The event includes a light breakfast and lunch. This event is free but space is limited to 60 participants and will fill up.
Ciara Miller says “DWTS” did not show enough of her personality beyond Bravo’s “Summer House” scandal
Miller and her pro partner, Brandon Armstrong, were eliminated from the competition in week 4.
Mid-Michigan entertainment for the weekend of Oct. 9-11 and beyond
Check out what’s happening this week.
Zara Larsson Floats Political Future With a Pop Star Twist
Zara Larsson is imagining a future beyond music, and her political ambitions come with a playful twist. The singer discussed the possibility of entering politics during an appearance on Las Culturista...
Inside Broward County’s battle for health care real estate
Broward County’s health care giants are racing to snap up real estate, competing for space amid rapid population growth and development. The county’s health care map, long dominated by a neatly defined duopoly between taxpayer funded hospital districts Broward Health and Memorial Healthcare System, is changing as an outpatient construction boom floods the market with new facilities and health care systems look beyond traditional medical real estate to expand their portfolios. But with prime development sites growing scarce, the county has emerged as a medical development battleground, with systems jockeying for land, market share and the opportunity to redraw the […]
I Played 6 Hours of Phantom Blade Zero and Can’t Stop Thinking About It
After half a day playing Phantom Blade Zero, it’s gone from mostly not on my radar to to the top of my wishlist this fall, and I truly cannot wait to dive back in later this month to see if it can deliver beyond those first handful of hours. At least for now, though, just about everything I’ve seen and played has made me more convinced that this is going to be one of the coolest action games of 2026.
Bill Nye the Science Guy experiments with prevalent topics at Beyond the Conversation
Bill Nye, known to generations as “The Science Guy,” took the Beyond the Conversation stage Wednesday as Titans filled TSU Pavilions A, B and C, welcoming the legend himself with
Beyond game day: How connected workflows are modernizing sports and entertainment venues
See how digital workflows help the Browns and Patriots connect stadium design, construction, project data, and operations.
Consumer Groups Call on Congress to Act on Health Care Price Transparency, Beyond the Trump Administration’s Data Cleanup Announcement Today
Congress should pass legislation to create a federal standard in law that stops hospitals and insurers from skirting price transparency rules.
Editorial: What would socialist policies mean for the middle class?
With Election Day less than a month away, voters should look beyond campaign slogans and ask what the policies on the ballot would mean for families who built their lives
Xbox Goes Beyond Games With XP, A New Entertainment Powerhouse
Microsoft has launched XP, a new Xbox division headed by Kayleen Walters that will oversee films, TV shows, consumer products, and theme parks.
The Math Singularity Is Here, and Science May Be Next
OpenAI has released an extraordinary body of mathematical work produced by an unreleased frontier model: 722 manuscripts spanning 372 research families across fields including number theory, complexity theory, and mathematical physics. Each result required, on average, the equivalent of roughly three hours of ChatGPT Pro reasoning. A New Era of Discovery We may be witnessing the beginnings of a “math singularity”: a point at which machine-generated discovery accelerates beyond humanity’s ability to independently reproduce, verify, or fully absorb it. If frontier models can generate hundreds of meaningful results in the time it takes a human researcher to investigate one, the constraint will no longer be producing new mathematics. It will be our capacity to validate, interpret, and integrate it. This does not make mathematicians obsolete. It changes their role. They may increasingly serve as guides, critics, and meaning-makers. Increasingly, they will decide which questions matter, determining which results can be trusted, and explaining why they are important. Mathematical insight may become abundant, while human judgment becomes more valuable than ever. Mathematics May Be Only the Beginning Every scientific discipline could eventually experience a similar acceleration. AI systems could generate and test hypotheses, connect findings across specialized fields, and explore possibilities at a scale no human research community could match. In medicine, imagine models identifying overlooked disease mechanisms, designing drugs and clinical trials, personalizing treatments, or discovering cures in months rather than decades. In materials science, AI could help create better batteries and cleaner industrial processes. In climate science, it could accelerate advances in energy, forecasting, and carbon removal. In biology, it could uncover relationships hidden across enormous genomic and molecular datasets. The result would not simply be faster research. It could expand the frontier of what is scientifically possible. The New Bottleneck Scientific discovery, however, is not the same as scientific progress. A medical breakthrough must still survive laboratory testing, clinical trials, regulatory scrutiny, manufacturing constraints, and real-world deployment. As machine-generated ideas multiply, the bottleneck may shift from producing breakthroughs to validating them safely and translating them into practice. We may soon have more hypotheses than laboratories can test, more drugs than clinical trials can evaluate, and more mathematical results than experts can review. That imbalance will require better systems for automated verification, reproducible research, prioritization, peer review, and collaboration between AI and domain experts. The importance of OpenAI’s work is not merely the number of manuscripts produced. It offers a glimpse of a world in which intelligence can explore thousands of intellectual paths in parallel. If ideas cease to be scarce, humanity’s defining challenge will be deciding which are true, which matter, and how to turn them into progress. The math singularity is not the end of human inquiry. It is the beginning of a new kind—one in which machines expand the frontier of knowledge and humans decide where it should lead. Subscribe Share Leave a comment
Release | We’ve partnered with a podcast!
The Bundesliga Show (TBS) & Get German Football News (GGFN) are delighted to announce a brand new partnership for the 2026/27 season and beyond!As a result, there will be an alliance to bring you the ...
How athletic identity shapes students on, off the field
Michigan coaches help student athletes build identities beyond sports, as most face career endings after college.
For the love of the game: URI students travel to Ireland to cover, experience international sporting community
KINGSTON, R.I. – Oct. 7, 2026 – Nine University of Rhode Island Harrington School of Communication and Media students spent two weeks in Ireland this summer exploring the country’s sports culture while putting their reporting and storytelling skills to work. That experience left a profound impact on the students that went well beyond their reporting […]
Why the best HR chiefs understand the business
HR pros should know the business’s priorities beyond the people function’s scope.
No Estás Solo: A resource guide for Latinos seeking mental health support
Oct. 10 is World Mental Health Day. Though culturally competent care may be hard to find for Latinos, De Los compiled some mental health resources available in Los Angeles and beyond.
Beyond hours saved: Building the business case for agentic automation
The RPA-era ROI model misses most of the value agentic automation creates. This post gives AI center of excellence leaders a framework to size the full value of agents across time savings, exception handling, decision quality, and maintenance economics, and to prioritize which workflows to automate first.
Davenport promotes mental wellness during Mental Health Awareness Week
Davenport University focuses on mental wellness during Mental Health Awareness Week and beyond. Mental Health Awareness Week is observed Oct. 4-10 and is designed to break down the stigma surrounding mental illness, connect people with community resources and emphasize the importance of early detection and care. The university’s Wellness Center provides free
Beyond the Science: Building infrastructure for Maryland’s e...
Maryland’s quantum ambitions depend on more than research: an inclusive ecosystem of legal, policy and business support could shape who benefits from its growth...
Film Festival Will Screen ‘Beyond The Duplex Planet’
The Woods Hole Film Festival’s Dinner & A Movie series continues on Saturday, October 17, with “Beyond The Duplex Planet,” a new feature documentary by Emmy-winning, Grammy-nominated filmmaker Beth Harrington.
Housing, retail and entertainment space proposed near Highmark Stadium
Architectural design group Progressive Companies presented concepts Tuesday for a new area just beyond the old Highmark Stadium area.
Ace Bailey’s Versatility Starting to Shine for Jazz
Ace Bailey showed Tuesday that his impact for the Jazz can extend well beyond scoring as he enters his second NBA season.
The Business Case For SEO Is Changing; Budget Justifications Should Too
Build an SEO budget around revenue growth, revenue protection, shared infrastructure, and AI experiments to justify spending beyond organic traffic.
Service 1st marks 100 years in business, extends beyond mortgage lending
- Company traces its roots to 1926 and continues to grow with new products and expansion into more vertical markets -
Bridges explores Mary L. Good's impact on science, technology
Mary L. Good's story began in Grapevine, Texas, but her impact on science and technology was felt across the U.S. and beyond.
Bridges explores Mary L. Good's impact on science, technology
Mary L. Good's story began in Grapevine, Texas, but her impact on science and technology was felt across the U.S. and beyond.
Planning Beyond 2030: What SAP Business Suite 7 and SAP NetWeaver Customers Using Third-Party Databases or Java Need to Know
Understand the coming changes and what they mean in practice.
AMC Entertainment Holdings (AMC) Shares Just Moved, So What Is Driving Attention Now?
AMC Entertainment Holdings (AMC) has just refinanced about $3.97b of existing borrowings, rolling them into new first and second lien facilities and notes that run out to 2031 and beyond. The refinancing arrives after a volatile stretch for AMC Entertainment Holdings, with the share price at $2.95 and a 90-day share price return of 54.45%, alongside an 83.23% year-to-date gain that points to building short-term momentum, despite a weaker 3-year total shareholder return of 70.26% and a 5-year...
Pixar exhibit brings movie magic to Frost Science
Buzz Lightyear may have doubts about humans and space travel, but when it comes to bringing Pixar characters to life, filmmakers take technology to infinity and beyond.
Lane Johnson retires after changing the conversation around mental health
Lane Johnson’s decision to discuss his anxiety and depression publicly created an important legacy extending beyond his championships and individual honors
Atrium promises state workers lower copays beyond its State Health Plan deal
Treasurer Brad Briner said the program will raise members’ costs in the long run and “violates the spirit of who gets to run” the plan.
Inter-American Mental Health Week calls for intersectoral action to improve mental health in the Americas
More than 185 million people live with mental health conditions in the Americas. Addressing the challenge requires action beyond the health sector.Washington, D.C., 6 October 2026 (PAHO) – The Pan American Health Organization (PAHO) and the Organization of American States (OAS) are marking Inter-American Mental Health Week 2026 (October 5–9) with a call to strengthen intersectoral action to improve mental health and well-being across the Americas, where more than 185 million people live with a mental health condition.
The hotel TV privacy mistake that can follow you home
Hotel TV privacy risks go beyond forgotten passwords when you sign into Netflix or other streaming apps on shared devices you don't control.
MyVisito Expands Digital Business Cards From Contact Sharing to Bookings, Sales and Connections
One shareable digital card brings professional presence, bookings, sales, events and ongoing connections together, with no app required for the recipient.DOVER, DE / ACCESS Newswire / October 6, 2026 / today announced an expansion of its digital business card platform beyond contact sharing, bringing professional presence, bookings, sales, events and ongoing connections into the same shareable card.
Is it possible to preserve your memories before dying? The science is moving beyond science fiction
For most of history, preserving someone’s memories after death meant relying on photographs, letters, stories and the recollections of other people. Technology is now pushing that idea much further. S...
Is it possible to preserve your memories before dying? The science is moving beyond science fiction
For most of history, preserving someone’s memories after death meant relying on photographs, letters, stories and the recollections of other people. Technology is now pushing that idea much further. Scientists can record parts of brain activity linked to memory, researchers are mapping the neural networks that store experiences, and digital systems can preserve enormous amounts of a person’s voice, writing, images and personal history. That still falls far short of copying a mind. No technology
AIAS+ 2026 Brings Leading Scientists to San Francisco to Explore How AI Is Changing Scientific Discovery
The Tianqiao and Chrissy Chen Institute will bring leading scientists, AI researchers, engineers and innovators to San Francisco November 5–7 for AIAS+ 2026: AI Advancing Science & Society, a three-day symposium focused on one of the most consequential questions facing research today: How can artificial intelligence help scientists move beyond analyzing what is already known and accelerate new discovery?
List of DVD release dates for Oct. 6 and beyond
Following is a partial schedule of coming movies on DVD. Release dates are subject to change: OCTOBER 6: Moana 6: Jackass: Best and Last 6: Late Fame 6: Blades of
Which Premier League players got injured during the international break?
The current international break has stretched well beyond what fans are used to.But the three-week break is set to end now, as football enthusiasts eagerly wait for the Premier League action to resume...
Did New Science Board Just Shift BioCryst's (BCRX) Investment Narrative?
BioCryst Pharmaceuticals recently formed a seven-member Scientific Advisory Board made up of experienced rare disease and drug development leaders to guide its research, clinical plans and regulatory approach. The depth of this board, spanning big pharma R&D, AI driven drug discovery and rare disease commercialization, directly targets BioCryst’s execution risk as it builds a broader pipeline beyond its current portfolio. We will now examine how BioCryst Pharmaceuticals’ investment narrative...
Inaugural Delbert E. Day Lecture to be held Oct. 15
The first Delbert E. Day Lecture on Glass Science and Technology will be presented by Dr. Claudio Mazzali, vice president of global research at Corning, Inc. The title of his lecture will be “Precision at Scale: Navigating the Science-to-Factory Continuum that Reshapes Industries for Glass Manufacturing and Beyond.” The lecture will be held at 3:30...Continue Reading Inaugural Delbert E. Day Lecture to be held Oct. 15
Dungeons and Dragons: World of Warcraft – Everything You Need to Know
Dungeons and Dragons: World of Warcraft was announced way back in July, as the first Universes Beyond release for the storied tabletop RPG. And just like the MMO it's based on, D&D: World of Warcraft is absolutely massive.
After school programming, birthday parties and day camps at Brooklyn Science Spot in Carroll Gardens (sponsored) | Brooklyn Bridge Parents - News, Events and Family Services
Brooklyn families, get ready for a fall experience that goes beyond worksheets, screen time, and ordinary after-school programs and camps. At Brooklyn Science Spot, we are opening the door to a whole new way for children to learn, explore, and fall in love with science through hands-on discovery, creative thinking, and real-world STEM fun. Opening
2026 Outstanding Women in Business
The 18th annual Outstanding Women in Business awards recognize a dozen well-accomplished professionals from across the region and in many industries who go above and beyond. The committee selected the winners from more than 80 nominations, all of whom were worthy. The criteria evaluated each nominee’s professional achievements, community impact, ability to break the glass ceiling and mentorship of other professionals, particularly women. In addition to profiling these women in the following pages, the Worcester Business Journal will celebrate this year’s Outstanding Women in Business at a special luncheon on Oct. 28 at the College of the Holy Cross. To join the celebration of these exceptional women, visit WBJournal.com and register. – Mark Conti, editor This Year’s Judges Worcester Business Journal considered 54 Central Massachusetts professionals for the 2026 Outstanding Women in Business awards, based on 83 nominations. These nominees were independently evaluated by two volunteer judges, who scored each on their professional achievements, community contribution and mentorship of young professionals. Samantha P. McDonald is a partner at Bowditch. She is an experienced, client-focused real estate lawyer, concentrating on business and real estate property law. She has been recognized as a WBJ Power 100 in the Class of 2026 and a “Top Women of Law” in Massachusetts Lawyers Weekly. Dr. Kavita Babu is chief medical officer and vice president of medical affairs at Heywood Healthcare, where she provides strategic and clinical leadership to advance high-quality, patient-centered care across the organization. She is also a member of the WBJ Outstanding Women in Business Class of 2025.
Three Preseason Goals For Bulls' First Round Pick Dailyn Swain
To secure his place in Chicago’s future, the versatile rookie must rediscover his offensive aggression, leverage his elite defensive length, and prove he can impact winning beyond scoring.
Collaborating with Canadian Scientists on Marine Carbon Dioxide Removal Research
I first met Dr. Helen Gurney-Smith in fall 2024, when Dr. Shannon Meseck and I drove just beyond the U.S.-Canada border to the St. Andrews Biological Station in New Brunswick. We went there to study larval sea scallop respiration when exposed to near-future temperature and pH. This past winter, Dr.
Scientists reveal what seven days of fasting does to the human body
Scientists found that prolonged fasting triggers major changes throughout the body, but many of the most interesting effects only appeared after about three days without food. The results suggest fasting may influence health in ways that go beyond weight loss and could eventually inspire treatments that mimic its effects.
Innovation That Solves: From Business Needs to AI Solutions
Targeted AI innovation transforms business challenges like hydrocarbon compliance into effective technological solutions, writes Jorge Mandujano.
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth
Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine
Rethinking discovery: how powerful screening tools are redefining the search for new medicines
In medicine discovery, identifying the right biological target has always been a critical and complex step. Today, the rise of powerful screening tools is fundamentally reshaping this process, creating a step-change in how we move from scientific hypotheses to transformative medicines. Advances in high-throughput screening, genomics and AI-driven analytics are enabling scientists to interrogate disease biology at unprecedented scale, bringing forward opportunities that were previously beyond reach.
This Kenner 'beach' thrives on volleyball, cold beer, decades of camaraderie: 'We're still here'
If it weren’t for the glowing lights of Planet Fitness and Treasure Chest Casino at the strip mall a few feet away, you could almost forget this beach is in the middle of a parking lot in Kenner. Here’s why locals drive from New Orleans and beyond each week to hang out, play ball or drink a few cold ones.
Behind bars and beyond capacity: The mental health crisis in prisons
Open Access Government reflects on data and efforts from concerning the prevalence and care of mental health disorders among prisoners
BUSINESS BRIEFS October 5, 2026: Business news in the Berkshires and beyond
Business news from Berkshire Money Management, MountainOne, BerkShares, The Clark, and more
Rembrandt etchings offer insight into the master’s vision
This exhibition offers a rare opportunity to explore Rembrandt's etchings up close, revealing intricate details visible with provided magnifying glasses, highlighting his innovative techniques and storytelling beyond his famous paintings.
OnMed, Jackson Health System and The Salvation Army Deploy OnMed CareStation™ to Extend Care Beyond Hospital Walls in Miami
Health system-sponsored CareStation creates a new front door to comprehensive, everyday care while strengthening connections to Jackson’s broader network of services SEPTEMBER 30, 2026 – OnMed, the leader in hybrid healthcare expanding access to care through the CareStation, today announced a new partnership with Jackson Health System, Miami’s only public health system, and The Salvation […]