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Four popular supplements that science says don't deliver
Walk into the supplement aisle and you’ll find plenty of products promising better health. But sometimes, basic chemistry and biology tell us those claims simply don’t add up. Before spending money on the next supplement promising better memory, faster recovery, or improved health, look beyond the label and examine the evidence.
How Female Biology Could Solve the Mystery of Longevity
Why do women live longer than men? An evolutionary question sparks a new hypothesis that dovetails with a growing movement in longevity research.
Fernbank Museum to explore the ‘Secret World of Elephants’ this fall
Visitors to Fernbank Museum of Natural History will have the opportunity to explore the intelligence, biology, cultural significance and conservation of elephants when a new exhibition opens this fall.
UCSB Researchers Unveil 10 Rules for Generative AI in Science
UC Santa Barbara's NCEAS has released a 10-rule framework in PLOS Computational Biology to guide environmental scientists using generative AI for coding.
‘Snake Men’ by Zach St. George
Who gets to name a newly discovered species is an unsettled question in the world of biology. Conflicts over taxonomy can become venomous.
Meet the science desk: Where research meets the world
Dear readers, My name is Maci Lesh, and I’m the new science editor, a title I still find a little funny, given I have spent most of my life actively avoiding anything that required a calculator. I was the kid who groaned through biology and negotiated my way out of every math class I could....
Pittsburgh professor achieves Guinness World Record for longest career as male science instructor
A biology professor at the Community College of Allegheny County has achieved the Guinness World Record as the longest-career science instructor (male).
The science behind later school start times
As Pennsylvania districts consider later bells, Penn Medicine sleep and neuroscience experts explain why adolescent biology can make early school start times especially challenging.
Temple workshop highlights the power of art in teaching science
The College of Science and Technology led a workshop for local high school biology teachers on using art to teach complex science topics. Teachers also received a demonstration of MEGA, an evolutionary analysis software developed by Temple faculty Sudhir Kumar.
Eastlake science students make district history
Three Eastlake High School students made Sweetwater Union High School District history this year when they became the first students from the district to qualify for the International Science and Engineering Fair, an international competition that brings together some of the top high school researchers from around the world. Ronald Wyatt, Giles Del Priore and Ihan Sung advanced to the competition after successful runs at regional and state science fairs. Sung went a step further, placing fourth in the chemistry category at ISEF. The students were recognized on Aug. 10 during a Sweetwater Union High School District board meeting at the district office in Chula Vista.For Wyatt and Del Priore, recent Eastlake graduates, the journey began with a shared concern about dementia and the challenges faced by families caring for loved ones with memory impairment. Their engineering project, “Design and Evaluation of a Behaviorally Grounded Caregiver-Governed AI Companion for Individuals with Memory Impairment,” earned the Sweepstakes Award at the Sweetwater District STEM Fair and first place in its division at the Greater San Diego Science and Engineering Fair. The project explored whether Artificial Intelligence could provide companionship and support while helping reduce stress for people with dementia and their caregivers. “Our inspiration came from personal experience. Both of us have seen family members and loved ones affected by dementia, and we’ve witnessed how overwhelming the caregiving process can be,” Wyatt said. Del Priore said the students also wanted to address the high cost of third-party health care services while creating something that could potentially help their own families as well as people elsewhere. The students developed an AI system designed with safeguards intended to prevent misinformation reinforcement, emotional escalation and unsafe responses. In 240 controlled trials involving memory, identity, agitation and neutral scenarios, they said the system consistently prevented harmful incorrect reinforcement while using context-aware silence, de-escalation and caregiver verification. The project required the students to combine Artificial Intelligence, psychology, neuroscience and human-computer interaction. For Del Priore, one of the biggest technical challenges was getting the AI companion to communicate verbally with a patient. Hardware limitations required the students to collaborate with multiple Python libraries for speech-to-text and text-to-speech functions while keeping the cost of the companion low. “For us, the biggest challenge was translating complex behavioral and cognitive care principles into a functioning AI system,” Wyatt said.Qualifying for ISEF was a milestone that student expected. The international competition proved to be another milestone. “Competing at ISEF was an incredible experience and unlike anything we’ve ever done before,” Del Priore said. “Being surrounded by some of the most talented young researchers from around the world was both inspiring and motivating.” He said the experience stood out because of the emphasis on collaboration, innovation and scientific discovery. “The most memorable part was seeing how people from completely different backgrounds and disciplines approached solving real-world problems with creativity and passion,” he said. The students also credited teachers and mentors who supported their work. Del Priore said his sophomore-year AP Physics teacher, Dr. Price, was particularly influential. “Through all of my personal and academic struggles, Dr. Price always believed in me,” Del Priore said. “All of his faith in me really molded me into the person I am today and helped create my love for science even through tough times.” Wyatt is continuing his education at UC Santa Cruz, where he plans to study biomolecular engineering and bioinformatics, with an interest in research involving Artificial Intelligence, biology and health care. Del Priore plans to double major in chemistry and accounting. Sung, a rising Eastlake senior, qualified for ISEF after winning first place in the Engineering: Energy, Materials & Transport category at the Greater San Diego Science and Engineering Fair and first place in chemistry at the California Science and Engineering Fair. His project, “Renewable Ammonia Electrochemical Synthesis by Glow Discharge with an Iron-Based Catalyst,” involved a device he designed and engineered to produce renewable ammonia, with potential applications in fertilizer production and energy storage. Sung became interested in the project after considering the relationship between food insecurity and fertilizer costs. His system uses plasma to break apart nitrogen molecules so they can interact with hydrogen and form ammonia. At ISEF, Sung competed against more than 1,700 students from 65 countries and earned fourth place in chemistry. “I am proud to become one of te first students in the district to qualify for ISEF because this milestone can inspire others in the district to attain similar goals,” Sung said.
4-Hers learn about biology, livestock at animal science day camp
On June 30, Lycoming County 4-H hosted its first-ever animal science day camp, Barnyard Bonanza, giving youth the opportunity to explore livestock through hands-on learning, demonstrations, and educational activities. According to a news release. the camp focused on livestock species and introduced participants to a variety of animal science topics. During the morning session, participants […]
New minor explores how biology, behavior and society shape health
Rice’s new undergraduate minor examines the biological, psychological and social factors that shape health.
Sea Aggie Researchers Make Evening Fun with Science on the Beach
“The environment is where we all meet; where we all have a mutual interest; it’s the one thing all of us share.” – Lady Bird JohnsonOn Galveston Island, beaches rank among the favorite environments to share and study, and, as Texas A&M University at Galveston faculty emphasized last week, are “More Than Just Sand.”A program subtitled “The Secret Life & Value of Sandy Beaches” drew more than 40 people to the Aug. 13 meeting of Surfrider Foundation Galveston, a local chapter of a nonprofit focused on the protection and enjoyment of oceans and beaches.The evening began barefoot with ecology lessons on the sand before moving across Seawall Boulevard for beverages, bites, and more beach talk at an area establishment. Drs. Guilherme Corte and Yasmina Shah Esmaeili show how a mesh bag is used as a sieve to separate organisms from samples of the sand. Credit: TAMUG Divisions of Marketing and CommunicationsNot far from where others were enjoying the attractions at Pleasure Pier, Drs. Guilherme Corte and Yasmina Shah Esmaeili introduced the ecologically curious to species living within the sediments.“When people hear ‘coral reefs,’ they immediately think of fish, live ecosystems, but when they think of sandy beaches, they think party, recreation, vacations – not coastal ecosystems,” said Corte, an assistant professor of marine biology in the College of Marine Sciences and Maritime Studies at TAMUG.Shah Esmaeili co-founded the Gulf eDNA Network and works with Corte in TAMUG’s Benthic Ecology Lab.“Sandy beaches are indeed great places for leisure and recreation,” Corte said. “Let’s keep enjoying them, because they are awesome. But they are also full of life that we most of the time don’t realize is there.”The married couple soon had the beachcombers measuring the slope with PVC poles, searching for ghost shrimp with a stainless-steel pump, sifting for marine worms and sand fleas, and guessing which species would burrow fastest back into the sand once released.Away from the sand, the focus turned to research from Drs. Ashley Ross ’03, ’10, and Virgie Greb, ’25 and those words from Lady Bird Johnson reminding people that the environment isn’t separate from their daily lives.“It’s about things that we value, mostly our communities, strong local economies, outdoor recreation, cultural connections, and our overall quality of life,” said Greb, a proud BOI – born on the island – Galvestonian, who now works in Austin as a project manager for the Texas General Land Office. “Along our coast, these benefits are deeply interconnected.”Greb and Ross, an associate professor in marine and coastal environmental science with the College of Marine Sciences & Maritime Studies, have studied a variety of ways beaches and the sea are important to Galveston and those who live there. Drs. Ashley Ross (left) and Virgie Greb (standing at right) field questions after their presentation. Credit: TAMUG Division of Marketing and CommunicationsIn 2023, using three survey methods – online for Galveston County residents, in-person at beaches, and paper distributed via city water bills – they collected 732 complete responses, 53 percent from residents and 47 percent from visitors.Most were frequent beachgoers who gave the recreation value of Galveston beaches a “B” and rated amenities such as restaurants, lodging, shopping, and beach access highly. Lower rated were water clarity and restroom facilities.“It’s noticeable that primary residents actually rate water quality higher; they’re more tolerant of hard, turbid water,” Ross said, crediting them with better understanding the natural conditions with the Trinity and San Jacinto Rivers bringing sediments and rich nutrients to the area around Galveston.Island residents also were more likely to understand that “clear” isn’t the same as clean beach water and to know that water quality is regularly tested. Clean means absent of disease-causing pathogens.“We need more education and outreach focused on water quality and the benefits of Galveston beaches and shores and water,” Greb said. “And it’s not just for tourism. There are a lot of people who are very lucky to live on an island with beaches and the bay.”
Smithsonian Brings Sandy Beach Scientists to Texas A&M Galveston
Scientists from the U.S. and South America are workshopping at Texas A&M University at Galveston (TAMUG) this week to expand sandy beach research and broaden collegiate learning opportunities.The Tides of Opportunity Project, co-led by the Smithsonian’s Marine Global Earth Observatory (MarineGEO) Program, TAMUG, the Smithsonian Marine Station, the Smithsonian National Zoo and Conservation Biology Institute, and the University of Miami, is a collaborative monitoring project with marine science professors and their students.Tuesday, Aug. 18, through Friday, Aug. 21, 15 professors and marine science professionals from the United States, Brazil, Peru, and Urugay will co-design a sandy beaches monitoring protocol and associated course modules and test the protocol in the field.The goal is to incorporate sandy beach monitoring protocols into marine science courses, which college faculty and students can use to achieve learning goals while providing essential data can help researchers diagnose the health of an understudied critical coastal habitat.Dr. Guilherme Corte, an assistant professor of marine biology in the College of Marine Sciences and Maritime Studies at TAMUG, is a principal investigator for MarineGEO. Texas A&M University at Galveston students and faculty package samples collected on the beach to take to campus for study in the Benthic Ecology Lab. Credit: TAMUG Division of Marketing and Communications“One third of the world’s ice-free coastlines are made of sandy beaches, and they go from pole to pole,” Corte said.However, despite their abundance and place as one of the most accessible coastal ecosystems for college-level education and research, they remain critically understudied.The Tides of Opportunity Project recognized that accessibility makes sandy beaches uniquely suited for engaging professors and students, including those with limited resources.“Any students can do sandy beach research,” Corte said, encouraging instructors to help students take a break from typing questions into artificial intelligence tools and embrace opportunities to do real science. “Providing this hands-on experience is something unique.”Tides of Opportunity Project goals include:Training a cohort of professors from across the Americas in standardized sandy beach monitoring methods; Equipping participating faculty with classroom modules, field tools, and multilingual teaching materials; Expanding MarineGEO with new monitoring sites focused on the implementation of long-term sandy beach monitoring; Strengthening hands-on, college-level learning experiences; And cultivating interest, learning, and efficacy in science among college-level students.By the end of this week, workshop participants plan to have a final version of the protocol and associated course modules that we can share with professors shortly after the workshop ends to then test with their students in courses that take place between September 2026 and February 2027.The scheduleDay 1: Tuesday, Aug. 18Location: Aggie Special Events Center (ASEC), Rooms 102 B and C, Texas A&M University at Galveston 8:30 – 9 a.m. Breakfast9 – 9:30 am Welcome and brief group introductions9:30 – 10 a.m. Introduction to Tides of Opportunity Project, Design Workshop, MarineGEO, and the Connecting Coastlines to Campuses Program (presentation)10 a.m. – 1 p.m. Introduction to workshop participants and project coordination team (presentations by each participant)• Brief lunch break from 12-12:30 p.m.1 – 3 p.m. Discussion about why collaborative science matters (presentation and interactive group discussion)3 – 4:15 p.m. Introduction to sandy beaches (presentation and group discussion)Day 2: Wednesday, Aug.19Location:• Morning sessions: ASEC Rooms 102 B and C, Texas A&M University at Galveston • Afternoon sessions: Corte’s field site (location available upon request)8:30 – 9 a.m. Breakfast9 a.m. – noon Prep for fieldwork (presentation and interactive group discussion)• Finish conversation about importance of studying sandy beaches• Go through sandy beaches monitoring protocol and field sheetsNoon – 12:45 p.m. Lunch12:45 – 1:30 p.m Prep for field (including driving to the field site)1:30 – 5:30 p.m. Fieldwork & bring samples back to TAMUGDay 3: Thursday, Aug. 20Location:• Breakfast: ASEC Rooms 102 B and C, Texas A&M University at Galveston • Fieldwork: Guilherme’s field site (location available upon request)• Lab/afternoon sessions: TAMUG lab (location available upon request) and ASEC Rooms 102 B and C8:30 – 9 a.m . Breakfast9 – 11 a.m. Return to field• Shorter field trip – recovering samples left out overnight11 a.m. – noon Lab work12 – 12:45 p.m. Lunch12:45 – 2:45 p.m. Continue lab work3 – 5 p.m. Discuss with professors the feasibility of implementing protocol in their courses and where might need to make changes (discussion)Day 4: Friday, Aug. 21Location: ASEC Rooms 102 B and C, Texas A&M University at Galveston 8:30 – 9 a.m. Breakfast9 a.m. – noon Group Discussion• How to evaluate student learning and engagement• Course modules• Next steps
AI needs science’s search history
“Actually, that’s where the gold is,” said Alasdair Russell, my graduate school friend who leads a pre-clinical genome editing group at Cambridge. He was talking about the winding road of science that is omitted from published papers. “When you’re discussing how to do the experiment, and why this way is better than another way, and what does the data really mean? I know what it shows, but what does it mean?” At RAAIS 2026, he described how his group has begun logging the twisting path of discovery as it happens, recording the verbal and written exchanges that normally disappear. Ideas become nodes in a living graph: they branch when a meeting produces two plausible experiments, merge when separate lines of evidence converge, and go dark when someone quietly stops pursuing them. In his implementation, one agent scores novelty, while another tries to learn “how scientists think and how they navigate through a complex world of data,” so that high-potential nodes can trigger deeper investigation. As frontier AI labs deploy agents toward scientific discovery, giving AI authentic scientific taste remains a trillion-dollar dilemma. The bottleneck is that the record we have kept for centuries of science might be insufficient to get us there. The experiments that never make the paper Peter Medawar, 1960 Nobel laureate and “father of transplantation,” asked in 1963 whether the scientific paper was a fraud, and answered yes: the form of the paper misrepresents the thinking that produced it. Sixty years on, the diagnosis is unchanged. A paper presents a clean progression from hypothesis to result to conclusion. Lost along the way are the unconventional theories, the abandoned or unaffordable methods, and the underwhelming and inconclusive data. It reads like a browser history with every dead end deleted: the ten open tabs, the four rephrased queries, the wrong turn down a subforum. All scrubbed, leaving one clean path from question to answer as the canonical path. What has changed since then is that the discarded material is now worth something. No high-impact journal wants these artifacts, but raw trial and error is the most likely source of the training data required to develop scientific intuition, or what researchers call taste. Earlier attempts to capture the discards were motivated by scientific integrity. The Journal of Negative Results in Biomedicine launched in 2002 to publish rigorous studies that disputed established models or exposed ineffective treatments. Its archive preserved negative conclusions after they had become papers, rather than the live alternatives and arguments that produced them. BioMed Central closed it in 2017, saying the mission had been served now that other journals publish null results. A less generous reading is that in fifteen years it published around 200 papers because almost nobody wants to read a negative result, let alone write one up when it will not count toward academic tenure. AI models are different. Even an uninteresting negative result can be useful, provided it is labeled. Earlier this year, Anthropic put a version of this to the test. The company pulled 129 decision points from real Claude Code sessions between January and March 2026, showed models the work up to a human detour, and asked what should happen next. Claude Mythos Preview beat the human choice 64% of the time, while Opus 4.5 managed 51%. The comparison was tilted toward the models because Anthropic deliberately chose moments where the human decision had room for improvement. On 127 further scenarios where the human action was already strong, the models improved on it only about 20% of the time. The study was possible because Anthropic’s researchers work inside a tool that logs by default. The reasoning, detours and outcome are produced in the same working environment. Biology has no equivalent. Its reasoning happens in hallways, at benches, in Slack threads and on whiteboards, while the outcome arrives weeks later somewhere else. The record has to emerge from the work itself. Ask scientists to reconstruct it afterwards and we’ll create another polished account. Subscribe A log is not a label Before any of this becomes training data, a negative result has to say what failed. The first paper published in the Journal of Negative Results in Biomedicine examined 234 negative studies across five leading medical journals. Only 30% discussed statistical power, and half clearly defined a primary outcome. Tell a model an experiment failed, without telling it whether the assay was underpowered, a reagent had degraded, or the hypothesis was simply wrong, and it will learn noise with confidence. Decision histories have a second missing label too. When a lab considers five experiments and runs one, only the chosen branch returns an outcome. The other four are experimental counterfactuals. Researchers call this the selective labels problem: the data reveal results only for the actions someone chose to take. Such a record can teach a model to imitate a lab’s taste, but it cannot establish that the taste was good. It also smuggles local constraints into general lessons. A lab that never ran cryo-EM because it did not own a microscope teaches a model that cryo-EM is rarely the right call. Alasdair’s nodes preserve the candidate set, which is the necessary first step. To be useful, each decision record needs six fields: The evidence available at that moment, and nothing that arrived later. The candidates considered, including the ones dismissed in a sentence. For each candidate: the expected result, the confidence attached to it, and the cost in time and money. The route chosen, and the reason. What happened next. How the evidence changed the scientist’s view. These must be timestamped before the outcome, because hindsight turns uncertainty into inevitability. Disagreement also has to survive. Averaging three scientists into one clean rationale reproduces exactly the information loss we are trying to fix. But there is an obvious failure mode here. Once decisions are logged and scored, people log for the record post-facto. Anyone who has watched an electronic lab notebook fill up with retrospective tidying knows how quickly a research tool becomes a compliance exercise. A record that costs a scientist ten minutes of honest reflection per decision is worth far more than one that costs an hour of performance. A publication initiative called Registered Reports offers a useful starting point. Here, researchers submit their rationale, methods and analysis plan for peer review before the data exist, and the journal commits in principle to publish if they follow the approved plan. Nature has now expanded the format across every field it covers. This approach to paper writing timestamps intent before the outcome, but it freezes one plan. A useful search history must also preserve how the plan changed, which alternatives were rejected, when, and on what evidence. Subscribe Run the runner-up Autonomous labs show what happens when decisions and outcomes are connected in a loop. Liverpool’s mobile robotic chemist ran 688 experiments over eight days in a ten-variable formulation space. A batched Bayesian search used each result to choose the next experiments and found photocatalyst mixtures six times more active than the starting formulations. Every completed experiment changed what the system did next. The robot optimized within a goal and search space that humans had already chosen. It did not decide which scientific question mattered. So what this work demonstrates is narrower, but still useful: a search history pays off when the options return standardized outcomes quickly. Open-ended biology is harder because branches can take weeks and the discarded alternatives may never be run. Some exploration therefore has to be bought. Where two branches are plausible and the stakes justify the cost, a lab should sometimes run the runner-up. Otherwise the record captures what today’s scientists usually chose and stays silent on what they systematically overlooked. A funder could ring-fence a small fraction of a grant for the branch not taken, provided that the decision record and the outcome are both deposited. That costs money, but so does having every lab rediscover the same abandoned path. Test whether taste transfers When it comes time to evaluate if our new AI system exhibits taste, the comparison should run across laboratories and fields. At selected decision points in a live research campaign, we should freeze the six fields: the evidence, the candidates, expected results, confidence, costs and the choice made. Experts then rank the options before the outcomes are known, and those outcomes are checked independently later. We could give models one of two diets - papers alone, or papers plus decision histories - and ask them to rank the next experiment on unfamiliar projects. Then, we score information gained per dollar and week, calibration, and how quickly weak branches are abandoned. If histories improve choices only inside the lab that produced them, they amount to useful organizational memory. If they improve choices on unfamiliar problems elsewhere, Alasdair’s group will have captured something science has never managed to write down: a transferable record of taste. Until that happens, a scientific search history is a promising record, not yet a training set.
Seven Virginia Tech faculty elected to 2026 Virginia Academy of Science, Engineering, and Medicine
The new members represent the university's research breadth in wireless communications, cybersecurity, cancer biology, medical education, AI, drug delivery, and comparative oncology.
Astorg Acquires Thermo Fisher Microbiology Business, Forms Independent Company
Astorg has completed its acquisition of Thermo Fisher’s microbiology business, which will operate independently under CEO Dirk Bontridder.
Radiologists criticize noted neuroscientist podcaster’s claims supporting whole-body MRI
Andrew D. Huberman, PhD, a professor of neurobiology and ophthalmology at Stanford Medicine, voiced support for these scans in a recent social media post.
Scientists Release Biggest 2D Map of the Universe
Key Takeaways The DESI Legacy Imaging Surveys combined more than 263,000 telescope exposures to make the largest 2D map of the universe in visible and near-infrared light. Astronomers can pair the Legacy Surveys map with their own observations to explore our universe and search for rare phenomena. The 2D map serves as the foundation for the Dark Energy Spectroscopic Instrument survey to measure the universe in 3D and investigate dark energy. Hold on to your telescopes: the DESI Legacy Imaging Surveys team has released the largest-ever 2D color map of the universe. The 5.6-trillion-pixel map contains nearly 4 billion celestial objects, primarily stars and galaxies. The data is available for all to use and publicly viewable through the Legacy Survey Sky Viewer. Astronomers and citizen scientists can explore the map or combine it with their own observations to better understand our universe. Researchers can search for rare phenomena like gravitational lenses, observe fleeting events like supernovae, and investigate two of physics’ biggest mysteries: dark matter, the invisible substance that accounts for most of the mass in our universe, and dark energy, the force driving our universe’s accelerating expansion. The new map builds on earlier versions from the DESI Legacy Imaging Surveys that have already proved invaluable. To date, more than 1,800 science papers that reference the Legacy Surveys data have been published. “It’s part of the fabric of astronomy research now,” said David Schlegel, a co-lead of the Legacy Surveys and scientist at the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab). “When you’re working with astronomical objects today, you often start by pulling up the Legacy Imaging Viewer to see what you’re looking at.” Covering roughly 75% of the sky in visible and near-infrared light, the updated map provides a deep view of the extragalactic universe not blocked by the dust and stars of our own Milky Way. Researchers expect it will remain the most comprehensive 2D map of our universe for years to come. More than 160 scientists contributed to data collection for the project, and a team of 20 produced the final dataset released today. It was built by combining 263,407 telescope exposures from three ground-based sky surveys: the Dark Energy Camera Legacy Survey (DECaLS) at NSF Cerro Tololo Inter-American Observatory, the Mayall z-band Legacy Survey (MzLS) at NSF Kitt Peak National Observatory, and the Beijing-Arizona Sky Survey (BASS) at the University of Arizona’s Steward Observatory. That was supplemented by years of data from NASA’s Wide-field Infrared Survey Explorer (WISE) satellite mission and additional public data. “For our team, these data are fundamental to our investigation of the expansion history of the universe and the formation of our galaxy,” said Arjun Dey, co-lead of the Legacy Surveys and an astronomer at NSF NOIRLab. “But the skies belong to everyone, and this survey gives everyone the chance to explore the sky and marvel at its wonders.” Here be galaxies The DESI Legacy Imaging Surveys were originally conducted to prepare for the Dark Energy Spectroscopic Instrument (DESI) survey. The Legacy Surveys’ 2D map is essentially a deep photograph of the sky; it records where galaxies and stars appear and how bright they appear. This crucial step enables DESI to select objects and measure their light in different wavelengths to determine their distances, building the largest high-resolution 3D map ever made. Scientists study the way galaxies have clustered at different ages of the universe to track dark energy over time. In April 2026, DESI completed its original five-year survey ahead of schedule and with vastly more objects than expected. The early results have shown surprising hints that dark energy’s impact may be weakening over time — a paradigm shift that could potentially shape the predicted fate of our universe. DESI expects to publish improved results using their first five years of data in 2027 and is continuing observations into 2028. DESI was so efficient at observing galaxies, the Legacy Surveys map needed to expand. Early on, “it became clear we might run out of galaxies to look at and run out of sky, and we better start doing something about that,” said Schlegel, who also works on DESI. The new Legacy Surveys map has been used to select DESI targets since June 2026 and will guide the telescope’s operations over the coming years. Computing the cosmos Merging hundreds of thousands of images taken on 2,285 nights, each with unique atmospheric and telescope conditions, was a massive computational effort. It took about a year to develop the computer code and eight weeks to process all the images at the Perlmutter supercomputer at the National Energy Research Scientific Computing Center (NERSC) at Berkeley Lab. Beyond supporting DESI, the Legacy Surveys will be a foundational reference for the next generation of telescopes. As new observatories like the NSF-DOE Vera C. Rubin Observatory (jointly funded by NSF and DOE’s Office of Science) and NASA’s Nancy Grace Roman Space Telescope come online, researchers can compare their observations with one of the deepest and most comprehensive views of the sky ever assembled. The Legacy Surveys data will also help scientists train artificial intelligence tools to analyze petabytes of astronomical data and accelerate new discoveries. It will be among the datasets used in an astrophysics pilot project within the American Science Cloud, part of the DOE’s Genesis Mission. The DESI Legacy Imaging Surveys are supported by the U.S. Department of Energy’s Office of High Energy Physics; the National Energy Research Scientific Computing Center, a DOE Office of Science user facility; the U.S. National Science Foundation, Division of Astronomical Sciences; and the partner institutions. DESI is supported by the DOE Office of Science and NERSC. Additional support for DESI is provided by the NSF; the Science and Technology Facilities Council of the United Kingdom; the Gordon and Betty Moore Foundation; the Heising-Simons Foundation; the French Alternative Energies and Atomic Energy Commission (CEA); the Secretariat of Science, Humanities, Technology and Innovation (SECIHTI) of Mexico; the Ministry of Science and Innovation of Spain; and by the DESI member institutions. ### Lawrence Berkeley National Laboratory (Berkeley Lab) is committed to groundbreaking research focused on discovery science and solutions for abundant and reliable energy supplies. The lab’s expertise spans materials, chemistry, physics, biology, earth and environmental science, mathematics, and computing. Researchers from around the world rely on the lab’s world-class scientific facilities for their own pioneering research. Founded in 1931 on the belief that the biggest problems are best addressed by teams, Berkeley Lab and its scientists have been recognized with 17 Nobel Prizes. Berkeley Lab is a multiprogram national laboratory managed by the University of California for the U.S. Department of Energy’s Office of Science. DOE’s Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit energy.gov/science.
Ott receives leadership award from Society for the Study of Reproduction
Troy Ott, Peter and Ann Tombros Dean of Penn State’s College of Agricultural Sciences, has received the Distinguished Leadership and Service Award from the Society for the Study of Reproduction, one of the organization’s highest honors recognizing exceptional leadership and selfless service in advancing the science of reproductive biology.
Translating Science into Practical Management Solutions
Biology in the barn can translate science into practical management solutions
$500K National Science Foundation Grant funds interdisciplinary mathematical biology research at Elon
The National Science Foundation (NSF) has awarded Associate Professor of Mathematics Hwayeon Ryu and Assistant Professor of Biology Efra Rivera-Serrano a three-year, $500,138 grant to study viral...
F&M Brewing Science
Rob Jinks, professor of biology, who teaches the Brewing Science class at Franklin & Marshall College, dispenses a New England Indian Pale Ale into a pitcher inside Fair Trade Cafe
The computer science major is dying so that the AI literacy minor can be born: ‘we have to democratize it’
Computer science enrollment is falling even as psych, music and biology majors rush into AI minors — colleges are racing to keep up with employer demand.
Stephanie White, let me 'educate' you on the science of why men don't belong in women's sports
Stephanie White said she wasn't educated enough on the science of males in women's sports. Here's what biology and sports science say about fairness.
Scientists found evolution repeating itself in the Galápagos Islands
More than 150 years after Darwin’s finches helped reshape biology, Galápagos plants are exposing another evolutionary surprise. Giant daisies repeatedly developed similar heat-tolerant leaf shapes, but each lineage used a different combination of genes. Researchers also found major genetic differences among isolated populations, suggesting new species may be forming right now.
Recursion to Report Second Quarter 2026 Business Updates and Financial Results on August 5th
Company to host public Earnings call on August 5th at 8:00 am ET / 6:00 am MT / 1:00 pm BSTSalt Lake City, UT, July 29, 2026 (GLOBE NEWSWIRE) -- Salt Lake City, UT, July 29, 2026 (GLOBE NEWSWIRE) – Recursion (Nasdaq: RXRX), a leading clinical stage TechBio company decoding biology to radically improve lives, announced today it will provide business updates and report its second quarter 2026 financial results on Wednesday, August 5, 2026, before the open of the financial markets. Recursion will h
At UCSB, this science education program sparks connection, innovation among kids - Santa Barbara News-Press
For around 15 years, SciTrek has led one-week lessons on topics including physics, biology, conservation of mass, fermentation and cellular respiration
When It Comes to Fusion, Materials Matter
Fusion at high temperatures powers the sun and, if harnessed, could provide a potential source of energy here on Earth. But controlling fusion reactions has other benefits. The process also generates subatomic particles called neutrons that are used in a range of applications spanning medicine, research, and national security. Now, scientists at the University of California, Davis (UC Davis), and the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have found that the materials surrounding a fusion reaction can dramatically increase how often it occurs, particularly at low energies where fusion is rare. The study was published July 18 in Nature Communications. Their approach sets up a way to study and engineer nuclear reactions within solid materials, opening a new field of “materials-driven fusion.” Instead of designing materials just to survive the harsh conditions of fusion, researchers might be able to design materials that boost the reaction in specific conditions, similar to the way catalysts speed up chemical processes. “It gives you a new knob to turn that you didn’t have before,” said Arun Persaud, head of the Fusion Science & Ion Beam Technology group in Berkeley Lab’s Accelerator Technology & Applied Physics (ATAP) Division. “If we understand this effect better, it opens the door to engineering new materials that would affect the fusion rate under certain conditions. Someday future progress might enable more compact and efficient neutron generators, which have all kinds of applications, like cargo screening, planetary science, and medical therapy and imaging.” In the experiment, researchers used two different methods to pack deuterium, a heavy form of hydrogen atoms that is often used in fusion, into thin foils of palladium and titanium. They then fired a beam of deuterium ions at the foils at different energies and measured how often fusion happened. Then they compared the rates from the different materials and methods with the “bare” fusion reaction (not in a material). The team found that fusion rates depended on how the deuterium was loaded into the metal foils. The biggest effect was at the lowest energies, below 2.5 kiloelectronvolts (keV), where theory predicts fusion rates drop off sharply. Instead, researchers found a surprising plateau: Some samples showed elevated fusion rates roughly a quintillion times higher than bare fusion reactions. (A quintillion is a 1 followed by 18 zeroes.) Researchers are not exactly sure why that’s happening, though they have some ideas and ways to test them. The electrons and defects within the material might partially shield repulsive electrostatic forces between deuterium nuclei, making it easier for them to get close together and fuse. Tuning the electronic structure, defects, and composition of materials could help make nuclear reactions happen more readily. “It comes down to better understanding the mechanism so that we can try to enhance it,” said corresponding author Jeremy Munday, a professor at UC Davis. “We’ve seen that we can increase fusion rates, but what is the limit? Can we bring it to lower temperatures or energies? There’s obviously a lot of interest and excitement about fusion, so if there’s something we can learn about the physics at these lower energy scales, maybe there’s something we can translate to other areas of nuclear science.” The team plans to explore a wider range of materials and continue probing the unexpected fusion plateau at lower energies. Their work establishes a reproducible experimental platform to study how solid materials influence nuclear reactions, creating a new area of research that links fusion science with materials science and chemistry. “The work shows conclusively that the material environment where fusion occurs at low temperatures is an active participant rather than a passive container,” said Cameron Geddes, director of ATAP. “That adds a new dimension to fusion research.” This work was funded by the U.S. Department of Energy’s Advanced Research Projects Agency-Energy (ARPA-E). ### Lawrence Berkeley National Laboratory (Berkeley Lab) is committed to groundbreaking research focused on discovery science and solutions for abundant and reliable energy supplies. The lab’s expertise spans materials, chemistry, physics, biology, earth and environmental science, mathematics, and computing. Researchers from around the world rely on the lab’s world-class scientific facilities for their own pioneering research. Founded in 1931 on the belief that the biggest problems are best addressed by teams, Berkeley Lab and its scientists have been recognized with 17 Nobel Prizes. Berkeley Lab is a multiprogram national laboratory managed by the University of California for the U.S. Department of Energy’s Office of Science. DOE’s Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit energy.gov/science.
Mosquito research draws KSU environmental science major to the woods for the summer
Kennesaw State University senior Brooklyn Galvan has found a happy place for the summer – in the mosquito-infested woods near Hattiesburg, Mississippi. The environmental science major is conducting research into mosquitoes as pollinators as part of the National Science Foundation’s Research Experiences for Undergraduates for Gulf Coastal Plains Ecology. The experience builds on Galvan’s experience researching the importance of mosquitoes to the ecosystem in the lab of KSU Assistant Professor of Microbiology Andrew Haddow.
Israeli students win 13 medals at international science Olympiads
Israeli students earned 13 medals, including five golds, at international physics, biology, and chemistry Olympiads held worldwide in July.
Researcher receives NSF CAREER Award to advance insect biology and strengthen South Texas agriculture
The UT San Antonio research project will also support the training of undergraduate students and expand K-12 science education.
New Deadline For NASA Astrobiology Science Conference (AbSciCon) Announcement for Partnership Proposals (AFPP)
NASA’s Science Mission Directorate (SMD), Astrobiology Program, is pleased to extend the deadline for the Announcement for Partnership Proposals (AFPP): Astrobiology Science Conference (NNH26ZDA009L) on the NASA Solicitation and Proposal […]
MEDaL-1 Mars Lander Science Definition Team
[ESA] Join the Science Definition Team (SDT) to help define the Exploration Science Payload for a proposed future Mars lander: MEDaL-1. Full announcement The European Explore2040 strategy expresses a bold […]
Animal science head named president of Society for the Study of Reproduction
Rebecca Krisher, professor of reproductive biology and head of the Department of Animal Science in Penn State’s College of Agricultural Sciences, was named president of the Society for the Study of Reproduction, effective July 22. She is the third Penn Stater to hold the gavel and lead the organization.
Chinese scientists have bad news on having babies in space
Researchers use China’s Tianzhou spacecraft missions since 2017 to study how microgravity and space radiation can affect biology.
Future scientists explore the wonders of biology at STC summer camp
From growing plants and examining cells under microscopes to culturing bacteria and dissecting organisms, middle school students are discovering the excitement of science through STC annual Biology Explorers Camp.
STC Biology faculty member inspires students to see science beyond the classroom
For South Texas College STC Biology faculty member Xiomara Galvan Garcia, science isn’t just a subject to memorize, but a way of understanding the world.
Industry partnerships, hands-on experiences turn waterways into science labs for biology graduate students
Biology grad students dive into hands-on research on local waterways, transforming them into science labs while forging valuable industry connections.
Can humans hibernate their way to Mars?
Scientists are trying to recreate the biology that lets animals survive months without food or water, in hopes of making deep-space travel possible
New Transfer Agreement Established for Fisheries Students
Under the agreement, Carteret Community College graduates will be eligible to transfer into NC State’s Bachelor of Science in Fisheries, Wildlife and Conservation Biology program.
How One STC Biology Instructor is Changing How Students See Science
For South Texas College (STC) Biology faculty member Xiomara Galvan Garcia, science isn’t just a subject to memorize, but a way of understanding the world.
Pythons' extreme biology may hold clues for treating human disease
These snakes can go for months without eating, grow and shrink the size of their hearts and jump start their metabolism on a dime.
At Family Science Night, Wonder Comes Before Answers.
BAR HARBOR—Family Science Night isn’t really about science. It’s about wonder. It’s about watching a five-year-old realize that the tiny creature under a microscope is a real living thing. It’s about a teenager discovering that the scientist explaining genetics or regeneration isn’t much older than they are. It’s about parents seeing curiosity spread across a child’s face the way excitement spreads across a crowd at a Fourth of July parade. For one evening, families realize that the laboratory isn’t some secretive place where knowledge is hidden behind white coats and closed doors. They learn that the lab is a place their neighbors work, their friends’ parents work, and it becomes a place where questions matter more than answers. It’s a place where wonder is the origin for knowledge. At the lab, children learn that it’s okay not to know. Adults remember that they once asked “Why?” about everything. Scientists are reminded why they fell in love with discovery in the first place. There are experiments, games, obstacle courses, and demonstrations, of course. But those are really just invitations—to touch, to explore, to laugh, to make mistakes, and to ask one more question. In a world that often rewards certainty, Family Science Night celebrates curiosity. And perhaps that’s its greatest gift. Long after the microscopes are packed away and the experiments are over, what families take home isn’t just a few new facts about biology. They take home the feeling that discovery belongs to everyone—that science isn’t something happening somewhere else by someone else. It’s simply what happens when people are given permission to wonder. A Family Science Night at the Mount Desert Island Biological Laboratory is one of those rare community events where children and adults can experience science as something they do, not just something they read about. Hands on discovery allows hands-on learning and joy. Real scientists, some local, some scientist-interns (but still scientists) just in college make science real, approachable, and exciting. And there, complex ideas like forever chemical-filtration, DNA and so much more become not complex. Instead, they become fun. Summer fellows are challenged to explain cutting-edge biomedical research in ways a first-grader—and their grandparent—can understand. Past activities have explored gene expression, kidney function, axolotl regeneration, worms, microplastics, and phytoplankton through games and creative demonstrations. Though it’s called family night, you can also see adults going from station to station, exploring, learning together across ages. Family Science Night reflects the laboratory’s broader mission of breaking down barriers between researchers and the public, helping people understand how scientific discoveries relate to everyday life and the health of Maine’s environment. Family Science Night transforms a world-class research laboratory into a giant interactive classroom, where curiosity is encouraged, questions are celebrated, and families discover that science isn’t just something that happens in a lab—it’s an adventure anyone can join. About MDI Biological Laboratory For more than 125 years, MDI Bio Lab has been a center for training and research in comparative biology. In the last two decades its biomedical research has focused on aging, regeneration, and environmental toxins. The Laboratory houses 11 research groups staffed by an international team of world-class scientists and graduate students. It also leads a statewide network of colleges, universities and research institutions that collaborate to provide training, research experiences and financial support to help young Mainers play a bigger role in today’s biomedical revolution. Located on Maine’s rugged coast, the Laboratory’s 100+ acre campus houses research facilities, cottages and dorms that house visiting scientists and students. It is also home to MDI Bioscience, a subsidiary working to design innovative techniques to speed the drug discovery process. LINKS TO LEARN MORE NIH INBRE MDI BIOLOGICAL LABORATORY Photos: Carrie Jones and Shaun Farrar/Bar Harbor Story HELP SUPPORT THE BAR HARBOR STORY When we started The Bar Harbor Story, we didn’t know if anyone would read it. But you showed up. You shared. You sent tips. Now—over 400,000 views every month later—it’s clear: people here care about their community and each other. We’ve kept everything free because news should never be out of reach, but every one of our stories takes time to write, and your support keeps The Bar Harbor Story going. If you value our work, please consider a paid subscription, a founding membership, or a sponsorship. It truly helps us cover one more meeting, tell one more story, shine one more light. Even $5 a month makes a difference. Click here to become a one-time supporter now. Thank you so much for being here. Founding member information can be found here. Have questions about sponsorships? Just send Shaun an email at sfarrar86@gmail.com, he’d love to hear from you. Subscribe Share Bar Harbor Story Share Leave a comment
The tiny cell that broke a big rule of biology
It took two scientists decades to find a new nitrogen-fixing organelle. It could change the future of sustainable agriculture.
Biological aging clocks in health and disease
Nature Medicine - This review outlines the state of the art of biological clocks and how they could help understand pathobiology, reduce the burden of disease and extend healthspan.
Intestinal muscularis in health and disease
Communications Biology - The authors review the intestinal muscularis – an increasingly recognized neuroimmune interface that orchestrates gut homeostasis, contributes to disease...
Binding us through science: Mt. Blue High honors biology Open House
FARMINGTON — The food court at Mt Blue campus is dotted with tables of poster presentations encircled by curious community members, serving up slices of science, community service, and free pizza for…
Science on Target: Q2 2026 Research Spotlight
Basic Biology Consortium breaks new ground in ALS In 2022, Target ALS awarded funding to Drs. Jonathan Cooper-Knock (University of Sheffield, project lead) and Michael Snyder (Stanford University), along with fellow consortium members Drs. Ophir Shalem (University of Pennsylvania) and Eran Hornstein (Weizmann Institute), for their project “Exploring the landscape of ALS genetics with machine […]
The ‘leading ladies’ of Science — inside the Microbiology Girls Club
It’s part science club, part mentorship program and part launchpad for the next generation of women in Science, Technology, Engineering, and Mathematics (STEM). But what really connects the girls inside this microbiology lab is curiosity and a community built on asking (and answering) questions.
Making the ‘invisible’ visible: How high-speed movies could change the way scientists study disease
An advanced imaging method captures chemical processes in living organisms in real time, allowing researchers to observe biology as it happens.
From recombinant DNA to AI: Who gets a say in powerful new science?
Professor Luis Campos studies the history of biology and biotechnology.
Why you should wash new clothes before wearing; signs that you are aging well; effective leadership in health care; plus other stories with Vanderbilt Health sources
Jami Miller, MD, Professor of Clinical Dermatology, and David Gaston, MD, PhD, Assistant Professor of Pathology, Microbiology and Immunology, are quoted in a Southern Living piece about the importance of washing new clothes before wearing them. Dyes, chemicals, mold and bacteria are all potential troublemakers lurking around your new duds. Parul Goyal, MBBS, Associate Professor of Clinical Medicine, was quoted in a Huff Post story outlining signs that you are aging well. Tae Kon Kim, MD, PhD, Assistant Professor of Medicine, was interviewed by Healio for a story headlined, “Effective leadership in health care ‘starts with listening.’” AAMC News reporter Patrick Boyle interviewed Wes Ely, MD, Professor of Medicine and Critical Care, for a story about ICU delirium. PharmaVoice reporter Kelly Bilodeau interviewed Romney Humphries, PhD, Vice Chair and Executive Medical Director, Clinical Services, for a story about the CDC’s new data that shows an alarming increase in the prevalence of a gene that can make “nightmare bacteria” significantly harder to treat. American Community Media interviewed William Schaffner, MD, Professor of Preventive Medicine, for a piece about Ebola that was reused by several media outlets around the U.S., including The Mississippi Link. Stacie Dusetzina, PhD, Professor of Health Policy, was quoted by The Independent in a story about how Medicare will soon cover weight-loss drugs. Courtney Schadt, MD, Associate Professor of Dermatology, was interviewed by Tennessean reporter Beth Warren, about tanning safety and tanning fads circulating social media. WKRN News 2 interviewed Amanda Peltier, MD, Professor of Neurology, about the correlation between head trauma and ALS following the diagnosis of former Titans running back Chris Johnson.
Students gain hands-on research skills during ASSURE summer science program
Liberty University’s ASSURE program, an annual six-week summer intensive through the School of Health Sciences’ Department of Biology & Chemistry, concluded last month with its largest participation yet, with 36 students gaining research experience under the supervision of 16 faculty members....
Scientists React to the Lab-Made, Yet Lifelike, SpudCell
This cell-like structure can grow, feed, divide and compete. Researchers ponder what it means for the future of synthetic biology and our definition of “life.”
ASU scientists unveil new methods to extract reliable truth from imperfect data
Scientists at Arizona State University are advancing how they interpret complex, imperfect data — challenging long-standing assumptions in fields ranging from imaging to cellular biology. In two papers published in Nature Communications and Proceedings of the National Academy of Sciences, the team introduces fundamentally new approaches to solving “inverse problems,” where researchers work backward from noisy observations to uncover the underlying reality.
Study Reveals Biology Underlying Oral Health Issues in Down Syndrome
Low saliva from calcium signaling dysfunction, microbiome changes may contribute to high rates of gum disease
SpudCell: Scientists Made a Cell With Most of the Hallmarks of Life. Here’s What to Know.
From why it was created to whether it’s alive, here’s what to know about SpudCell, the latest advance in synthetic biology.
Scientists say they have built a cell from scratch for the first time
Scientists say they have built a cell from scratch for the first time that feeds, grows and replicates like a natural cell, a breakthrough in synthetic biology.
Anthropic launches Claude Science AI workbench for researchers
Claude Science connects more than 60 databases and tools in one environment, running on existing Claude models with no specialized biology training
5 takeaways from Anthropic’s big science event
The company rolled out a biology-centric version of Claude and hosted surprisingly forthright conversations about AI and science.
Children’s Hospital Los Angeles’ 2026 TSRI Science Day Highlights Advances in Cancer Biology
June 17 saw more than 400 scientists, clinicians, research staff, and other Children’s Hospital Los Angeles team members come together for The Saban Research Institute’s (TSRI) yearly symposium and poster session—Science Day 2026.
Anthropic's New AI Workbench Mapped My Field For $26. Now Imagine It Aimed At The Rest Of Science
Anthropic's Claude Science is a capable AI research workbench built for molecular biology. The opportunities for the rest of science are enormous.
Biology alumni receive honor for undergraduate paleontology research
Julia Zottola ’26 and Sofia Corsico-Sánchez ’26 earn recognition from the Association for Women Geoscientists and the Paleontological Society
Faculty in Politics, Chemistry, Biology and English Appointed to Endowed Professorships | Pomona College in Claremont, California
Four faculty members have been awarded endowed professorship positions. The Pomona College Board of Trustees voted to support these appointments during their meeting in May.
Hood College Launches Accelerated One-Year Master of Science in Environmental Biology Track
Beginning in Fall 2026, Hood College's Graduate School will offer a new accelerated, 30-credit track within its Master of Science in Environmental Biology program, providing students with a pathway to earn their degree in just one academic year while gaining valuable hands-on research experience.
Careers That Shaped Biology
Every great scientific career begins with a question no one has been able to answer — and a scientist stubborn enough to keep asking it. This series looks back at the careers of some of HHMI’s most distinguished scientists — people whose contributions have changed what we know about life itself, and whose stories reflect the best of what science, and scientists, can be.
Efzimfotase alfa demonstrated improvements in bone health in treatment-naïve pediatric patients with hypophosphatasia achieving median difference of 1.67 vs placebo in RGI-C Score at week 25 in MULBERRY Phase III trial
Positive results from the MULBERRY Phase III trial showed that efzimfotase alfa (ALXN1850), an investigational enzyme replacement therapy, demonstrated a statistically significant and clinically meaningful improvement in bone health in children (2 to
Scientists Challenge a Fundamental Assumption About Consciousness
A new philosophical study challenges the idea that consciousness requires human-like biology.
Scientists stunned by signs of ancient life in a place no one expected
Scientists exploring ancient seafloor rocks in Morocco discovered mysterious wrinkle patterns where they were never expected to occur. These structures are normally linked to microbial mats in shallow, sunlit waters, yet the rocks formed hundreds of feet below the surface in darkness. Evidence indicates that chemosynthetic microbes created the wrinkles, revealing that deep-ocean microbial ecosystems may have been more widespread than previously thought.
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Regenerative Agriculture and Population Health
Regenerative agriculture can enhance food quality and reduce harmful exposures through improved soil biology, biodiversity, and ecosystem health, yielding downstream benefits for agriculture, food systems, and human health. It may improve profitability through greater land resilience and lower input costs and may deliver benefits to farms, farmers, communities, and the broader environment. More research is warranted to understand the full range of potential health benefits of regenerative agriculture.
The history behind the Marcus Alert System
Marcus-David Peters was a 24-year-old high school biology teacher at Essex High School when he died.
The universe may be hiding conscious minds stranger than we can imagine
What if consciousness isn’t limited to brains like ours? Philosophers Eric Schwitzgebel and Jeremy Pober argue that consciousness could arise in many different forms of life, even in beings built from radically different materials than those found on Earth. Drawing on the vastness of the universe and the likely existence of countless alien civilizations, they suggest it would be surprisingly Earth-centric to assume that only Earth-like biology can support conscious experience.
Offworld Space Biology: Setting Up The Life Science Glovebox
Bioengineering cartilage tissues and manufacturing advanced materials kicked off the week aboard the International Space Station
Pivot Fellow Natasha Blitvic Brings Math to Marine Microbiology
Pivot Fellow Natasha Blitvic Brings Math to Marine Microbiology on Simons Foundation
Behind this “ordinary snake,” scientists stunned by a hidden new species - Futura-Sciences
A Mysterious Snake Revealed Researchers from the Chengdu Institute of Biology, partnering with the Giant Panda National Park, have officially described a new species of tree viper: Trimeresurus lii, affectionately dubbed the Huaxi green viper. The discovery was made in early 2025 and published in the open-access journal Zoosystematics and...
Fermented food microbiome: influence on oral and gut microbiota, and human health
Nature Reviews Microbiology - The bioactive compounds and microbial consortia contained in plant-based fermented foods support oral and gut microbiota, host immune function and metabolic...
Moment of Science: “Antscan” project uses particle accelerator to map small insects in 3-D
It's the world of ants like you've never seen it before! Dan Smith shows how biology and particle physics are teaming up in the "Antscan" project. 🐜
Building a Roadmap for Hubble Science into the 2030s: Revealing Atmospheric Structure and Evolution in Substellar Worlds Using HST
Substellar objects occupy a unique place in our universe
KSU master’s graduates benefit from NIH-funded bridge program
Recent Kennesaw State University graduate April Ford engaged in a program designed to help master’s students in the College of Science and Mathematics gain the experience they needed to pursue doctoral degrees elsewhere. She’ll stand as an example of the Peach State Bridges to the Doctorate program’s effectiveness, having earned her Master of Science in Integrative Biology (MSIB) and acceptance into a Ph.D. program. Ford, Jojo Croffie, and Lindsey Knight all earned their MSIB degrees, and thanks to enrichment through the Peach State Bridges to the Doctorate program, each will start a Ph.D. in the fall.
ESA Exploration Science Workshop 2026 – Early Career Researchers Abstract Submissions
The European Space Agency is pleased to announce a Call for Abstracts for Early Career Researchers to submit abstracts to the ESA Exploration Science Workshop 2026
The surprising science of how fatherhood changes the brain
Recent studies suggest that, like mothers, fathers may undergo a profound shift in their biology and brains in preparation for and response to the responsibilities of parenthood.
Scientists reprogram brain immune cells to fight Alzheimer’s
A newly identified molecule called OLE helped restore the brain’s immune cells to a more protective state in Alzheimer’s models. The treatment reduced toxic plaque buildup and improved memory, raising hopes for a new therapeutic approach.
MSU Texas grad pursues health care mission through biology
For Joshua De Waal, a childhood experience with his dad’s accident made one thing clear: quality health care can change lives—and he wants to be part of that change.
MSU Texas grad pursues health care mission through biology
For Joshua De Waal, a childhood experience with his dad’s accident made one thing clear: quality health care can change lives—and he wants to be part of that change.
The surprising science of how fatherhood changes the brain
Studies suggest that, like mothers, fathers may undergo a shift in their biology in preparation for and in response to the responsibilities of parenthood.
Building Scientists in the AI Era
Stevens Institute of Technology’s newly launched AI in Biology and Chemistry Community helps students explore AI’s role in health care, biotech and ed-tech careers.
Cell and gene therapy's next challenge is not the science, it's everything else
The field's foundational biology is no longer the limiting factor. What comes next depends on whether the industry can build the manufacturing, commercial, and clinical infrastructure to match what the science already knows how to do.
These 36 Scientists Are Leading the Way to Biomedical Discoveries
On June 16, Pew announced the 2026 class of Pew Scholars Program in the Biomedical Sciences, Pew Latin American Fellows Program in the Biomedical Sciences, and Pew-Stewart Scholars Program for Cancer Research. These researchers will receive multiyear grants and join a community of more than 1,000 scientists who are taking creative approaches to cancer biology, neuroscience, immunology, and more.
NASA Spaceline Current Awareness List #1,204 12 June 2026 (Space Life Science Research Results)
NASA Spaceline Current Awareness List
These Portland trail guides build community through science, education and whimsy
“Drag Me Outside,” where field biology meets fabulousness.
Microbiology DNA and Chemistry for Health Insights Tops Research Schedule
Microbiology dominated the research schedule aboard the International Space Station on Thursday helping doctors protect health on Earth and in space. The Expedition 74 crew also tested a new spacesuit, packed a U.S. cargo spacecraft, and kept up lab maintenance throughout the orbital outpost.
Scientists discover a hidden cause of aging cells that can be reversed
Researchers discovered that declining levels of phosphatidylcholine may be a major cause of age-related mitochondrial dysfunction and loss of cellular energy. Remarkably, boosting this nutrient restored more youthful mitochondrial performance in aging organisms, suggesting some aspects of aging can be slowed or reversed.
In a first, scientists translated an entire viral genome so a quantum computer could read and analyze it
Scientists have uploaded a viral genome to a quantum computer, marking an important step for the future of quantum-enabled advancements in biology.
President’s message: Progress and opportunity for science and medicine
his is an extraordinary moment in time for the biomedical sciences. Seven decades ago, the discovery of the structure of DNA sparked a revolution in understanding life. In the decades since, the knowledge of fundamental biology we have accumulated has led to innovative treatments for many difficult-to-treat diseases, and many more are now within reach....
Hubble Science in the 2030s White Paper: High-Contrast Optical and UV Spectroscopy with HST/STIS
The Space Telescope Imaging Spectrograph (STIS) on the Hubble Space Telescope currently stands as the sole space-based astronomical facility providing visible-light coronagraphic imaging — and the only facility anywhere that can perform both visible- and ultraviolet-light coronagraphic spectroscopy. In imaging, STIS offers unparalleled stability that rivals the performance of ground-based direct imaging in the optical, […]
GREX-PLUS Science Book v2
GREX-PLUS (Galaxy Reionization EXplorer and PLanetary Universe Spectrometer) is a mission candidate for a JAXA strategic L-class mission to be launched in the 2030s
NASA Spaceline Current Awareness List #1,203 5 June 2026 (Space Life Science Research Results)
NASA Spaceline Current Awareness List
Planetary Science Analysis and Assessment Group Support
Earlier this year it was announced that NASA’s Planetary Science Division to cease financial support for planetary science Analysis/Assessment Groups (AGs), effective the end of April 2026.