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Scientists discover a major brain shift between ages 50 and 75
Scientists have uncovered sweeping changes in how the human brain controls and organizes its genome beginning in midlife, offering new clues to why aging sharply increases the risk of Alzheimer’s and other neurodegenerative diseases. One of the biggest shifts occurred between about ages 50 and 75, when many of the brain’s original immune cells declined and were replaced by cells with more inflammatory characteristics. Researchers also found weakening of cells that help maintain the blood-brain barrier, along with widespread deterioration in the genome’s three-dimensional organization.
DRC’s Ebola Lessons: Learned And Unlearned (Part I)
The lethality of the Ebola outbreak in the Democratic Republic of Congo (DRC) is not just in its genome. Neither is it entirely explained by the country’s
Pop superstar Olivia Rodrigo donated $2 million to Indigenous health organization
The Center for Indigenous Health is grateful for the upcoming donation — especially after experiencing federal grant cuts
NMSU alum inducted into Indigenous Athletics Hall of Fame
Cuyler Frank was inducted into the North American Indigenous Athletics Hall of Fame in May 2026 for his historical contributions to preserving the Navajo language through sports broadcasting.
Japan’s biomass energy boom threatens further deforestation in Indonesia
Expanding deforestation in Indonesia caused by the country’s wood pellet and chip industry is putting further pressure on tropical forests, Key Biodiversity Areas, and Indigenous territories in the archipelago, according
New Indigenous business lead ‘excited’ to help advance economic reconciliation
Canadian Council for Indigenous Business appoints Peter Dinsdale as president-CEO
Actor Tatyana Ali advocating for Black and Indigenous maternal health
Actor Tatyana Ali says her healing journey after a traumatic childbirth has inspired her advocacy for Black maternal health, including support for midwives, doulas and other birth workers.
Actor Tatyana Ali advocating for Black and Indigenous maternal health
Actor Tatyana Ali says her healing journey after a traumatic childbirth has inspired her advocacy for Black maternal health, including support for midwives, doulas and other birth workers.
Actor Tatyana Ali advocating for Black and Indigenous maternal health
Actor Tatyana Ali says her healing journey after a traumatic childbirth has inspired her advocacy for Black maternal health, including support for midwives, doulas and other birth workers.
Scientists find a new layer of Alzheimer’s hidden in the genome
Scientists found that the 3D organization of DNA is disrupted in several types of brain cells affected by Alzheimer’s disease, altering how important genes are switched on and off. The discovery reveals a previously underexplored layer of the disease that could open new paths for understanding and eventually treating Alzheimer’s.
New York Jets Flight Connections 09/12/26
Happy Saturday, Jets fans! Kickoff of the 2026 season is just one day away. Below are your Saturday Jets links to enjoy as we approach the final countdown. Randy Lange – Geno Smith, Jets Players Near Statistical Milestones This Season NY Jets – What’s the Most Important Matchup in the Jets-Titans? Amanda Vogt – Notebook […]
Moderna, 10x Genomics, Oscar Health, and Novavax Shares Are Soaring, What You Need To Know
A number of stocks jumped in the morning session after Morningstar reported that challenging macroeconomic conditions across broader equity markets drove a rotation into healthcare, lifting the sector index by approximately 7% quarter-to-date to reach a 5% valuation premium.
J.K. Rowling responds to Lilly Wachowski’s accusation of ‘funding trans genocide’ (exclusive)
J.K. Rowling’s representative responded to Lilly Wachowski accusing the author of ‘funding trans genocide’: ‘She does not support legal actions aimed at harming transgender people.’
Yosemite National Park highlights Indigenous arrowhead crafting
Called knapping, the skilled process dates back thousands of years.
Trump loyalist probing Mar-a-Lago search says DOJ tensions sparked his resignation
“Lanes got crossed,” Joe diGenova told NBC News after his departure from the Justice Department.
Moderna, 10x Genomics, Oscar Health, and Novavax Shares Are Soaring, What You Need To Know
What Happened? A number of stocks jumped in the morning session after Morningstar reported that challenging macroeconomic conditions across broader equity ma...
Prosecutor who led ‘grand conspiracy’ probe of Trump targets resigns without charging anyone
Joe diGenova, 81, was part of a group that tried to overturn the 2020 election.
Napoli Off to Their Worst Start in Over Twenty Years
Napoli began their campaign with a gritty win over Genoa but then lost three games in a row, resulting in their worst start in years. The last time they had begun this poorly was in 2000/2001, when th...
For these Midwest farmers, regenerative agriculture is about more than soil health. It's spiritual
A farmer in Minnesota has transformed a conventional farm using both formal agricultural education and the Indigenous wisdom he learned as a youth growing up in the Guatemalan rainforest.
Indigenous fisherwoman finds ‘lost’ spinach pipefish, not seen by science in 40 years
Founder’s Briefs: An occasional series where Mongabay founder Rhett Ayers Butler shares analysis, perspectives and story summaries. On the final day of a two-week expedition, where researchers were searching for a “lost” species along Papua New Guinea’s Sepik River, Helen Asu arrived with two small, greenish-brown fish. She had caught them while fishing for prawns […]
Nightingale Health and Genom to launch risk detection test in Croatia
Nightingale Health and Genom have partnered to introduce a blood-based risk detection test to clinics and laboratories throughout Croatia.
Spiraea genome reveals how Rosaceae evolved a key defense hormone
A chromosome-level genome of Chinese spiraea reveals how the rose family conserved and remodeled a major route for producing salicylic acid, a hormone central to plant immunity and environmental stress responses.
Google DeepMind’s AlphaGenome Takes Aim at One of Genetics’ Biggest Problems
Google DeepMind has released a huge new dataset that could make it easier for scientists to study how changes in our DNA affect the way the body works. Called AlphaGenome Atlas, it contains predictions for more than 9 billion possible single-letter changes in the human genome. The dataset is about one petabyte in size and […]
BGI Genomics Launches "Digital Life Twin" Framework to Power Proactive Health
Commemorating BGI Group's 27th anniversary, BGI Genomics today introduced its Digital Life Twin framework alongside an advanced multi-omics diagnostic portfolio at the 2026 Global New Product Launch Event. Grounded in over two decades of population-scale genetic discoveries, the launch marks a decisive transition from traditional, reactive diagnostics to continuous, predictive health management across the entire human lifecycle.
Indigenous Arts Initiative will offer workshops on arts, entertainment industry
The Indigenous Arts Initiative, which includes partners from the University of Kansas, will bring two distinguished Indigenous artists and educators to Lawrence this September for a series of free public workshops exploring art, culture, storytelling and filmmaking.
Ingenovis Health names new chief commercial officer
Nicole Gable joins Ingenovis Health as chief commercial officer to lead strategy for the Blue Ash-based health workforce staffing company.
Ingenovis Health names new chief commercial officer
Nicole Gable joins Ingenovis Health as chief commercial officer to lead strategy for the Blue Ash-based health workforce staffing company.
Paul Finebaum rips Geno Auriemma on state of college sports
Auriemma made headlines last week for his belief that college sports are "dying."
More Than 5,000 Leaders Across Entertainment, Academia and Public Life Unite to Reject “Genocide” Accusation Against Israel
Boris Johnson, Deborah Lipstadt, Sir Niall Ferguson, Shari Redstone, Steven Pinker, Sherry Lansing, Simon Sebag Montefiore, Chief Rabbi Warren Goldstein, Irwin Cotler, Debra Messing and thousands of others reject the genocide accusation against Israel and warn that it fuels antisemitism
Allegri counts on European 'motivation and adrenaline' for Napoli
Coach Massimiliano Allegri is hoping the arrival of Champions League football can help put Napoli on the right track after back-to-back defeats in Serie A. Victory on the opening day against Genoa has been undermined by successive defeats at the hands of Como and Inter Milan, leaving new boss Allegri looking for a reset when his side welcome Arsenal to Stadio Diego Armando Maradona on Wednesday evening.
Ratko Mladić funeral exposes gap between Serbia’s EU ambitions and political reality
A general convicted of Europe’s first genocide since World War II was buried Monday with military and religious honors, sparking alarm in Brussels.
Prof Elizabeth Streicher unravels the science behind drug-resistant TB
Prof Elizabeth Streicher of the Division of Molecular Biology and Human Genetics delivered her inaugural lecture on Tuesday 1 September 2026. Her research focuses on the transmission and spread of Tuberculosis (TB). Knowing where TB transmission is happening can help to stop it from spreading. Prof Elizabeth Streicher of the Division of Molecular Biology and Human Genetics in the Faculty of Medicine and Health Sciences delivered her inaugural lecture on Tuesday 1 September 2026. The title of her lecture was Decoding tuberculosis: the evolution of technology, epidemiology and the Mycobacterium tuberculosis genome. Streicher explained to Corporate Communication and Marketing how molecular epidemiology (using genetic information to track how and why diseases spread through populations) has improved our understanding of where drug-resistant TB comes from, how it spreads and how drug resistance evolves within and between populations. Tell us more about your research and why you became interested in this specific field. Overall, our research group studies the genome (complete set of DNA instructions found in a cell) of Mycobacterium tuberculosis, the bacteria that cause tuberculosis (TB) disease. Various regions of the genome are interrogated to study different aspects of the disease. My main focus has been on the epidemiology of tuberculosis – how the bacteria’s genome changes over time and what this tells us about the transmission and spread of the disease. How would you describe the relevance of your work? If we understand how the bacteria that cause TB change and spread, it can assist in combating TB globally. How has molecular epidemiology helped improve our understanding of drug-resistant TB? Molecular epidemiology was very important in drug-resistant TB as it was originally believed that bacteria that become resistant to antibiotics would be less fit and not be able to transmit. But it was shown that they can transmit, and therefore have to be monitored to identify hotspots of transmission and outbreaks, etc. Can you tell us briefly about the spoligotyping technique and its advantages for studying drug-resistant TB? Spoligotyping (a molecular technique used to identify and track specific strains of TB bacteria) does not detect drug resistance, but since the technique is relatively quick to do, it can be very useful in real-time situations, e.g. to monitor outbreaks of drug resistance. Why are interrupting transmission chains and identifying genomic hotspots important for controlling the spread of TB? Knowing where TB transmission is happening can assist in allocating resources to those areas to stop future transmission and spread of TB. Higher education can be challenging. What keeps you motivated when things get tough? Students – how they are so passionate and dedicated to learning and contributing to research and society as a whole. What aspects of your work do you enjoy the most? Again, the students and colleagues! But also the fact that it is continuously changing and thereby we are learning and expanding our knowledge. In the end, I know that we contribute to a better society in our small way. Tell us something exciting about yourself that people would not expect. Even though I love hiking (day and multi-day hikes) and being outside, I really do not like camping! How do you spend your free time? I love hiking (wellbeing in nature) and like to watch most sports. ©Higher Education Media Services. Subscribe
Reindeer and rare-earth minerals: Swedish politicians take aim at Indigenous Sami in mining dispute
Gabna community fear their traditional herding routes will be sacrificed as far-right rhetoric ramps up against them
Weekly Briefing: Politicians confront genocide and democracy as elections loom in Palestine, Israel, and the U.S.
Gaza’s markets have food but no buyers, Lebanon’s camps lose critical aid, and Palestine, Israel, and the U.S. head toward elections.
Super Bowl Winning HC Takes Blame for Geno Smith Struggles
A Super Bowl winning head coach took the blame for quarterback Geno Smith's struggles during the 2025 season. The post Super Bowl Winning HC Takes Blame for Geno Smith Struggles appeared first on HEAVY.
Indigenous knowledge helps reveal the ties between reefs and mangroves
In a recent scientific article in the journal Ocean & Coastal Management, alongside the list of scientist-authors were the Bardi Jawi and Oorany Rangers and the Bardi Jawi Traditional Owners. For the past decade, Bardi Jawi rangers and traditional owners have been working with the Australian Institute of Marine Science (AIMS) to study and protect […]
Chaminade (NY) stuns Hendricken with last-second TD
WARWICK, R.I. (WPRI) — Hendricken were stunned in their season opener on Saturday night, falling to Chaminade, 18-17. The Hawks led 17-12 with 2:02 left in the fourth quarter after a Jamel Flomo interception, but the Flyers were able to win the game thanks touchdown catch from Michael Genovese as time expired. Senior quarterback Isaiah […]
“No It Ain’t, Yelling at Clouds Guy”: Fans React As Geno Auriemma Claims “College Basketball Is Dying”
College sports have been in turmoil for quite some time now. There has been a lot of discourse about the NCAA’s eligibility, transfer portal, and NIL rules.
‘Fauda’ Creator Calls Mark Ruffalo ‘Ignorant’ Over 'Genocide' Remarks
'Fauda' creator Avi Issacharoff has called Mark Ruffalo as 'ignorant' on Israel-Hamas conflict.
Indigenous Cannabis Industry Association Receives Community Partnership Award
The Minority Cannabis Business Association presented the award, recognizing the ICIA for bridging the gap between policy and community leadership.
HERA Director-General visits Indonesia to strengthen health cooperation
The Director-General of the European Commission’s Health Emergency Preparedness and Response Authority (HERA), Dr Florika Fink-Hooijer, met with Indonesia's Minister of Health, H.E. Budi Gunadi Sadikin, in Jakarta on 4 September 2026. Discussions centred on Indonesia's expansion of surveillance capacities, including genomic sequencing as well as local manufacturing capacity. There was a clear commitment to work together on wastewater surveillance going forward. Earlier that day, Director-General Fink-Hooijer, met with the Secretary-General of ASEAN, Dr Kao Kim Hourn, at the ASEAN Secretariat to discuss health emergency preparedness and response to emerging health threats, and to explore deeper cooperation between the EU and ASEAN. More info on the meeting at the ASEAN Secretariat: https://link.europa.eu/HdVV7q
Science Division launches five new centers to foster multidisciplinary research in areas of growing importance and interest
These centers debuted July 1 with five years of initial funding and will focus on marine genomics, geohazards, materials innovation, RNA science, and astrobiology.
Scientists Find More Than 1,000 DNA Variants Linked to Personality Traits
More than one million genomes helped identify DNA variants linked to extroversion, agreeableness, neuroticism and more. Researchers measured how those traits influenced how people lived.
Just war is not the same as ‘genocide’
When one nation is singled out for an accusation reserved for no one else facing comparable circumstances, the motive is no longer the pursuit of justice.
Drought is deepening a health crisis among Peru’s recently contacted Indigenous Matsés
REQUENA, Peru — Until a century ago, few Matsés had ever been in contact with a white person before. The Indigenous people lived in a remote area of the Amazon Rainforest, along the border of Peru and Brazil, in seminomadic forest settlements between the Javari, Yaquerana and Gálvez rivers. There, wild meat was abundant — […]
Genome Duplication Is a Radical Evolutionary Gamble
By doubling their entire genome, organisms can evolve extremely rapidly — or they can lose it all. New studies reveal how to survive the high-risk, high-reward evolutionary event.
Indigenous Groups Are Exempt From Medicaid Work Rules, But Native Hawaiians Aren’t
Native Hawaiians will have to comply with the new work requirements in President Donald Trump’s signature One Big Beautiful Bill Act, despite facing significant obstacles to employment and healthcare.
August Monthly Review: ChatGPT In Epic
Death, taxes, another frontier lab healthcare launch inspiring truly insane LinkedIn takes. As much as I want to stay away, I repeatedly am the crewman unplugging his ears whenever we pass these sirens. So it’s not the first and probably not the last time we dial up the typewriter rather than tie ourselves to the mast. The full blow-by-blow timeline: Health API Guy is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe The End of the Standalone PHR (Jan 8): ChatGPT Health arrives for consumers, at the time powered by b.well. I was bullish on the approach in that the best way for the PHR to finally solve distribution was to meet consumers were they already are (i.e. When Horizontal Meets Healthcare (Jan 9): OpenAI for Healthcare puts out the shingle for enterprises, with SharePoint ingestion standing in for the EHR integration the product actually needed. Another One: Anthropic’s Healthcare Debut (Jan 16): Claude's version, on HealthEx rails instead of b.well, with Agent Skills for FHIR development as the one true vertical-specific investment. ChatGPT for Clinicians: The Trap Sprung (Apr 24): OpenAI filled in the missing GTM middle with a free product for verified clinicians, effectively peeling the enterprise wrapper off ChatGPT for Healthcare and taking the PLG fight directly to OpenEvidence. OpenAI’s Second Attempt at Health (Jul 31): a relaunch of their patient specific app, now branded Health in ChatGPT, where the privacy partition came out, the connectors thinned, and b.well disappeared in favor of first-party FHIR work against a smaller network Beyond a Shingle So what was announced now? Today, we’re introducing a new electronic health record integration that brings authorized patient context from Epic into ChatGPT for Healthcare, along with the Healthcare Public Data plugin for direct, structured access to official healthcare datasets like PubMed, DailyMed, and CMS Coverage. Together, these capabilities bring ChatGPT closer to the systems and sources healthcare teams trust, while supporting the controls and compliance healthcare work requires. The core portfolio is unchanged from prior announcements we delineated and discussed (aside from the relaunch of patient-facing). Since trade publications still seem to be confusing them by using the wrong names: Enterprise sales motion: ChatGPT for Healthcare Protecting their core product / PLG: ChatGPT for Clinicians Consumer/patient-facing product: Health in ChatGPT So really, this is a feature release (specifically for ChatGPT for Healthcare when it comes to EHR integration). What’s cool about it, though, is that we are moving beyond just putting out a shingle. Everything in the January enterprise launch was horizontalizable: Horizontal tech companies thus generally start verticalization with their “putting out a shingle phase”. Telling the world you’re open for business as a horizontal tech company reliably attracts early inbound interest from buyers who are already trying to force-fit horizontal tools into domain-specific workflows and are eager for any signal that the vendor intends to support their use case more directly. Nothing was really vertical specific, which is exactly what you'd expect from the ultimate hypergrowth horizontal company dipping their toes into specific industries. But eventually you have to stop changing the sign on the door and start changing the product. Can you guess where the horizontal product was going to run out of road? This is the core dilemma writ large: verticalization requires differentiation, while scale economics of consumer and horizontal push toward unification. I’ve buried the lede so deep here it will be painful to some readers, but what should be shocking to no one is that my perspective is that EHR integration is the only path that meaningfully resolves this tension for ChatGPT for Healthcare. Integration with Microsoft Sharepoint is fine, but it is categorically insufficient for any product that hopes to influence clinical decision-making. SMART Money Well here we are, eight months later! Real vertical investment has begun, which surprised a few people. One friend in the industry messaged me: “Absolutely no way Epic gave ChatGPT API access.” Looking forensically at the announcements, the integration is notably read-only across appointment notes, laboratory results, medications, and specialist documentation. So while I’m not a betting man, I'd wager the house this is a SMART on FHIR launch: That sounds a lot like USCDI! The recommended path for the workflow they outline would be SMART on FHIR Their Health AI lead’s post is evocative of both standalone and EHR launch SMART, which another termed “ChartGPT” and “EHR Plugin” The implementation burden for SMART on FHIR is the lowest of the available integrative paths This is the team who literally did patient-facing SMART on FHIR with Epic last month Most importantly, if you’re a horizontal company, you generally still haven’t taken the full plunge and thus (overly) value reusability. SMART on FHIR is the logical compromise: healthcare-specific enough to matter, but standardized enough to reuse. Nobody Asked Judy Another friend asked “I thought they had to go to each health system, or did they go direct to Epic and now health systems opt in?” Given the trust paradigms in healthcare, this functionally cannot be Epic hoovering up all the data for OpenAI and shoving ChatGPT in their customers’ faces (or they would revolt). However, I do believe the aforementioned terrible coverage by TechCrunch and other outlets is probably responsible for that question, given the 325 million reference. When using FHIR as a business associate to an Epic customer, there is no EHR gatekeeping to speak of, as that isn’t how fhir.epic.com works: You register an app You pick your APIs You test against the sandbox APIs You list as “Ready for Production” Hospitals pick your app You test and go live with them Bluntly, nobody had to say yes or no in Verona (nor were they given the chance). Vendor Services (their next developer tier up that I doubt OpenAI is using quite yet in this initial release) certainly has contractual paperwork that some resent, but even there, the twin pressures of mounting antitrust and information blocking make outright gatekeeping increasingly fraught. My friend’s sentiment is, to me, representative of a broader industry neurosis, perhaps a sort of scar tissue of prior eras: people assume the gate is still there and never actually try the door. There are certainly other ways Epic (and any EHR) can put its thumb on the scale, but they are not so dumb as to stand in front of a federally mandated API and play bouncer at this exact moment in time. So I think they can and probably should go deeper, as this release is at best parity and at worst behind vertical-specific competition. OpenEvidence did a basic SMART launch with Sutter Health in February, allowing for more convenient evidence search by providers. They then add patient-context (the equivalent SMART on FHIR flow to what we see here) when Cedars-Sinai went enterprise-wide in May. UpToDate has four distinct applications across deeper workflows like patient engagement listed in Epic Showroom and announced a partnership with Epic to power Art at UGM Abridge and other ambient scribes have invested deeply into the deepest bidirectional clinical copilot workflow with integrations well beyond SMART on FHIR. In that light, the “Who is OpenAI primarily targeting here?” is clear. This release brings them into striking distance of OpenEvidence, but not the others quite yet. They are the only one of the three you can reach without building something truly Epic-specific. When will they go further? Competition is a great motivator to overcome the horizontal demons and start building things that can’t be reused: not across industries, not across EHRs, maybe not past the customer you built them for. That’s the price of actually verticalizing. The question is if and when OpenAI will be willing to pay it. Month in Review Here is the monthly review. As a reminder, this is a regular round-up of the month’s posts and other content to surface things you may have missed across regulation, litigation, interoperability, and beyond. AI assistance is used in these bullet summaries so I can focus on articles. Articles Published: None this month Video Content: The Information Exchange: Standards-based Thruple Edition (Aug 14): Back to school for us too, with Brad reporting in from the CMS Health Tech Ecosystem’s one year anniversary in DC. We get into the January CMS-0057 deadline, the fall rulemaking reading list, and why enrollment still keeps most apps off FHIR. The Information Exchange: Epic Dúnadan Edition (Aug 25): A UGM roundup with Ryan Brickner joining for the first time to check our takes against what the building actually thinks. Rangers, Ergo sitting on top of EHI, and a down-market lineup that needs some cuts. Regulatory: Stacked Deck, Bad Hand (Aug 05): ONC’s website refresh took the entire HIT Policy Committee record with it, so I rebuilt the archive and went looking for the regulatory capture story everyone assumes is buried in there. Stacking the deck and winning the hand turn out to be very different things. The Sixth Generation of Patient Access (Aug 19): A quick catalog of the five generations of patient access we’ve layered on since HIPAA, and the two candidates now competing to be the sixth. One is planned. The other is the market routing around the plan entirely. Court cases: Three Cases Walk Into a Docket (Aug 06): Two surprise settlements cleared the board in a single week, and then Judge Maddox dropped ninety-four pages on Vyne v. Henry Schein. The sleeper is a DMCA holding that makes direct-to-database a considerably riskier business model. Epic v. Health Gorilla: Into the MDL (Aug 10): Nine class actions are headed to Miami, and the Panel signaled it wants to bring the case that spawned them along too. That would leave Epic arguing the requests were obviously fraudulent in one courtroom and unknowable in the other. Amazon v. Perplexity: Agents Are Legalized! (Aug 11): The Ninth Circuit vacated the injunction against Comet, holding that the user is the one accessing the servers rather than the company that built the agent. A real win for agentic access, and a much narrower one than the headline suggests. Veeva v. Epic: Come At Me, Bro (Aug 26): Epic’s response brief wants the dismissal affirmed and, unusually, wants the opinion published as precedent. Buried in it is Epic’s own description of what its non-competes actually prohibit, which current and former employees should read closely. EHRs: The Contract Epic Would Never Sign Today (Aug 04): A 1999 SEC exhibit catches Epic licensing nearly its entire product line, Tapestry included, to the company that became TriZetto. The marketing services menu attached to it is the part that will make you blink. Forecast from Verona (Aug 07): The Epic Almanac makes one argument six different ways: the AI is only as good as the networks behind it. Emmie headlines, Art’s context stack is the most ambitious part, and Penny finally gets an autonomous coding date on the calendar. Works With Epic MyChart (Aug 17): Epic’s first new Showroom category since the death of Workshop certifies hardware instead of software, badge on the box and all. Made for iPhone, but for blood pressure cuffs, and rough news for anyone selling the RPM stack sitting in between. UGM Hot Takes 2026 (Aug 20): Everyone else covered the AI announcements, so I went after Savvy deleting the payment gateway, Rangers as Boost with the timer removed, and a down-market lineup with too many entries. Plus the Health Grid tidbits I cannot help myself on. MyChart Central Grows Up (Aug 24): Device data and Emmie turn Epic’s identity hub into a full consumer platform, which is both a logical answer to ChatGPT and a bit of a mistake. It also happens to be the best scraping target Epic has ever shipped. Industry Analysis: The Wrong Yardstick (Aug 12): Vertical software keeps getting judged against Superhuman and Notion, which is the wrong bar entirely. Your user is comparing your product to a whiteboard and forty phone calls before lunch. Primitives vs. Abstractions (Aug 27): Developers want building blocks, systems of record prefer to hand out business logic, and both sides have a real case. There’s no test from the outside that separates the engineering reason from the competitive one, which is why this keeps ending up in court. Cross-industry Comparisons: The Two Kinds of Platform Power (Aug 18): Attention power and record power are different problems that keep getting handed the same regulatory toolkit. Congress’s latest swing at Big Tech shows both what’s possible and where it falls apart. The Dogs of (Platform) War (Aug 21): A CourtListener alert turned up a property management fight with healthcare’s exact shape and none of the Cures Act. Shell prospects, ghost accounts, a notetaker bot that came back to haunt someone, and a lawyer arguing both sides of the same theory in two states. Fractals All the Way Down (Aug 31): Yardi dominates property management right up until you zoom into one segment, where AppFolio owns it outright and Yardi doesn’t appear at all. Where you draw the line around a B2B software market is about to decide an awful lot of cases. Other News: If Judy Had the Courage (Aug 13): A short eulogy for the era when software was allowed to look insane: WinAMP, bold colors, and everything the grey chatbot era has taken from us. External Media: Portland Monthly Health Tech Meetup: Erin O’Brien channeled my own feelings - maybe it’s just because it’s August and beautiful, but the monthly edition of the PDX Health community meetup was a ripper. Make sure to reach out if interested to join for the next one. STAT’s Coverage of Epic This Month: Brittany Trang of STAT did a fantastic job of breaking the FTC investigation that’s been lurking, as well as UGM related coverage, so I had to give her her wish of a meme. Fall Conferences: I’m pumped to be kicking off my fall conference season in NYC at Nabla Accelerate next month, which Chrissy provided the link to apply for. Here’s the rest of my schedule in case you want to meet up: Commonwell (Redwood Shores, CA): Oct 13-14 Open@Epic (Madison, WI): Oct 21-22 eHealthExchange (Austin, TX): Oct 27 Sequoia Project (Austin, TX): Oct 28-29 HLTH (Vegas): Nov 15-18 RSNA (Chicago): Nov 29-Dec 3 Posts I Liked: HTI-6 Should Unbundle API Certification: Josh Mandel makes the case that HTI-6 should split (g)(10) into separate authorization and data certifications, so a PACS or a genomics platform can certify only the role it actually performs. Imaging is the urgent example, but the structure solves a much bigger problem. On implementing ePrior Auth with Epic: Scott Rossignol’s field notes from a live ePrior Auth build on Epic, including the two app registrations nobody warns you about and the CPT mapping problem waiting at the end. CMS-0057 implementations are going to be such a beast. Healthcare point solutions are starting to look a lot like streaming services: Spencer Dorn runs the cable-to-streaming arc against health IT and lands squarely on the bundling half of the cycle. Bundling can be good! It can also be bad! Life is nuanced. Health API Guy is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe
Seneca Nation calls for reversal of Trump’s ‘Lake America’ executive order
Seneca Nation President J. Conrad Seneca says it violates a more than 225-year-old treaty and shows a "blatant disrespect" for Indigenous people.
Trump says he will report NBC host to FCC for ‘rebuke or punishment’
The president’s latest in a string of threats against broadcasters followed a comment by Kristen Welker about “some mixed results” from his midterm endorsements.
Jets news: New York releases ex-Patriots, Browns quarterback
The New York Jets released quarterback Bailey Zappe on Saturday, per Rich Cimini of ESPN. Zappe was hoping to earn a backup QB role , but now he will need to look for a new opportunity. With Geno Smith leading the way and Cade Klubnik also on the roster, the Jets will move forward without Zappe. Zappe, 27, made his NFL debut during the 2022 season […] The post Jets news: New York releases ex-Patriots, Browns quarterback appeared first on ClutchPoints.
Scientists Found 6,000-Year-Old Human Remains. No Other People Share Their DNA.
If they have no ancestors or descendants, then who are they?
Jets’ Geno Smith Plans Leak Ahead of Giants Preseason Finale
The New York Jets’ plans for the preseason finale against the New York Giants have leaked out on social media.Brian Costello of the New York Post revealed on X, “Jets QB Geno Smith will not play tomorrow night against the Giants, per source. Most of the Jets starters who have played this preseason are expected […] The post Jets’ Geno Smith Plans Leak Ahead of Giants Preseason Finale appeared first on HEAVY.
Researchers identify traces of two ‘ghost’ ancestors in modern human DNA
Scientists uncovered DNA from two mysterious human ancestors hidden in modern genomes, revealing new clues about our evolutionary past.
Jets' 53-man roster prediction for 2026 NFL season
The New York Jets actually look like they have some genuine momentum. After dropping their preseason opener to Tampa Bay, Aaron Glenn’s team responded with a statement performance in Pittsburgh. Suddenly, the competition for roster spots feels considerably more consequential. Geno Smith has already demonstrated that the offense can operate […] The post Jets' 53-man roster prediction for 2026 NFL season appeared first on ClutchPoints.
Scientists find hidden “highways” guiding animal evolution
A sweeping analysis of thousands of animal genomes suggests that chromosomes do not evolve randomly but instead follow a limited number of irreversible “evolutionary highways.” These one-way genetic changes preserve clues to more than 600 million years of animal history and could even help researchers explore where evolution may head next.
UC Santa Cruz launches Center for Marine Genomics
UC Santa Cruz, known worldwide for both genomics and marine science research, is now bridging the gap between the two disciplines with its new Center for Marine Genomics. The center, which launched July 1, will bring opportunities for…
Mule helps scientists build the clearest horse and donkey genomes yet
A mule has helped researchers build the most complete reference genomes to date for horses and donkeys, giving scientists access to complex regions of DNA that earlier versions could not fully capture.
Bette Midler and Tyrese Gibson feud over AI-generated song: ‘Cultural genocide’
Bette Midler and Tyrese Gibson are feuding about AI-generated music: ‘What HUMAN writer and SINGER IS gonna write a song that’s better than this??’
Government Science Websites Shouldn’t Apologize for Scientists
The job of a government science website is to inform the public about what science has discovered, not to pass judgment on historical figures for their alleged failure to live up to contemporary progressive standards of opinion. Someone should make that distinction clear to the men and women at the National Human Genome Research Institute (NHGRI).
Geno Smith is on the field at Jets practice Monday
Geno Smith was a late scratch for the Jets' preseason opener due to a sore ankle, but there was no concern from the team about an extended absence and Monday brought good news about his condition.
Coppa Italia Live: Follow Sunday’s First Round fixtures and results
Check the line-ups and live scores as they happen in the Coppa Italia First Round, with Frosinone-Juve Stabia (18:00 local time), Genoa-Ascoli (18:30), Hellas Verona-Virtus Entella (20:45) and Lazio-M...
A long-held indigenous practice continues to protect the health of the Moosic Mountain ecosystem in Lackawanna County
The Nature Conservancy recently held an educational day to discuss how prescribed burns help the ecosystem on Moosic Mountain in Lackawanna County.
Armenian Genocide survivors' grandson says 'political motives' block recognition
In 1915, the Ottoman Empire began the systematic deportation and massacre of its Armenian population. As many as 1.5 million Armenians were killed – widely regarded by historians as the twentieth century's…
Octavia Spencer Talks Giving 'Visibility' to Missing Indigenous Women
The narrator and executive producer of the ID series talks about the "duty" she feels to amplify the stories of missing and murdered native women and the current efforts toward seeking justice.
AI needs science’s search history
“Actually, that’s where the gold is,” said Alasdair Russell, my graduate school friend who leads a pre-clinical genome editing group at Cambridge. He was talking about the winding road of science that is omitted from published papers. “When you’re discussing how to do the experiment, and why this way is better than another way, and what does the data really mean? I know what it shows, but what does it mean?” At RAAIS 2026, he described how his group has begun logging the twisting path of discovery as it happens, recording the verbal and written exchanges that normally disappear. Ideas become nodes in a living graph: they branch when a meeting produces two plausible experiments, merge when separate lines of evidence converge, and go dark when someone quietly stops pursuing them. In his implementation, one agent scores novelty, while another tries to learn “how scientists think and how they navigate through a complex world of data,” so that high-potential nodes can trigger deeper investigation. As frontier AI labs deploy agents toward scientific discovery, giving AI authentic scientific taste remains a trillion-dollar dilemma. The bottleneck is that the record we have kept for centuries of science might be insufficient to get us there. The experiments that never make the paper Peter Medawar, 1960 Nobel laureate and “father of transplantation,” asked in 1963 whether the scientific paper was a fraud, and answered yes: the form of the paper misrepresents the thinking that produced it. Sixty years on, the diagnosis is unchanged. A paper presents a clean progression from hypothesis to result to conclusion. Lost along the way are the unconventional theories, the abandoned or unaffordable methods, and the underwhelming and inconclusive data. It reads like a browser history with every dead end deleted: the ten open tabs, the four rephrased queries, the wrong turn down a subforum. All scrubbed, leaving one clean path from question to answer as the canonical path. What has changed since then is that the discarded material is now worth something. No high-impact journal wants these artifacts, but raw trial and error is the most likely source of the training data required to develop scientific intuition, or what researchers call taste. Earlier attempts to capture the discards were motivated by scientific integrity. The Journal of Negative Results in Biomedicine launched in 2002 to publish rigorous studies that disputed established models or exposed ineffective treatments. Its archive preserved negative conclusions after they had become papers, rather than the live alternatives and arguments that produced them. BioMed Central closed it in 2017, saying the mission had been served now that other journals publish null results. A less generous reading is that in fifteen years it published around 200 papers because almost nobody wants to read a negative result, let alone write one up when it will not count toward academic tenure. AI models are different. Even an uninteresting negative result can be useful, provided it is labeled. Earlier this year, Anthropic put a version of this to the test. The company pulled 129 decision points from real Claude Code sessions between January and March 2026, showed models the work up to a human detour, and asked what should happen next. Claude Mythos Preview beat the human choice 64% of the time, while Opus 4.5 managed 51%. The comparison was tilted toward the models because Anthropic deliberately chose moments where the human decision had room for improvement. On 127 further scenarios where the human action was already strong, the models improved on it only about 20% of the time. The study was possible because Anthropic’s researchers work inside a tool that logs by default. The reasoning, detours and outcome are produced in the same working environment. Biology has no equivalent. Its reasoning happens in hallways, at benches, in Slack threads and on whiteboards, while the outcome arrives weeks later somewhere else. The record has to emerge from the work itself. Ask scientists to reconstruct it afterwards and we’ll create another polished account. Subscribe A log is not a label Before any of this becomes training data, a negative result has to say what failed. The first paper published in the Journal of Negative Results in Biomedicine examined 234 negative studies across five leading medical journals. Only 30% discussed statistical power, and half clearly defined a primary outcome. Tell a model an experiment failed, without telling it whether the assay was underpowered, a reagent had degraded, or the hypothesis was simply wrong, and it will learn noise with confidence. Decision histories have a second missing label too. When a lab considers five experiments and runs one, only the chosen branch returns an outcome. The other four are experimental counterfactuals. Researchers call this the selective labels problem: the data reveal results only for the actions someone chose to take. Such a record can teach a model to imitate a lab’s taste, but it cannot establish that the taste was good. It also smuggles local constraints into general lessons. A lab that never ran cryo-EM because it did not own a microscope teaches a model that cryo-EM is rarely the right call. Alasdair’s nodes preserve the candidate set, which is the necessary first step. To be useful, each decision record needs six fields: The evidence available at that moment, and nothing that arrived later. The candidates considered, including the ones dismissed in a sentence. For each candidate: the expected result, the confidence attached to it, and the cost in time and money. The route chosen, and the reason. What happened next. How the evidence changed the scientist’s view. These must be timestamped before the outcome, because hindsight turns uncertainty into inevitability. Disagreement also has to survive. Averaging three scientists into one clean rationale reproduces exactly the information loss we are trying to fix. But there is an obvious failure mode here. Once decisions are logged and scored, people log for the record post-facto. Anyone who has watched an electronic lab notebook fill up with retrospective tidying knows how quickly a research tool becomes a compliance exercise. A record that costs a scientist ten minutes of honest reflection per decision is worth far more than one that costs an hour of performance. A publication initiative called Registered Reports offers a useful starting point. Here, researchers submit their rationale, methods and analysis plan for peer review before the data exist, and the journal commits in principle to publish if they follow the approved plan. Nature has now expanded the format across every field it covers. This approach to paper writing timestamps intent before the outcome, but it freezes one plan. A useful search history must also preserve how the plan changed, which alternatives were rejected, when, and on what evidence. Subscribe Run the runner-up Autonomous labs show what happens when decisions and outcomes are connected in a loop. Liverpool’s mobile robotic chemist ran 688 experiments over eight days in a ten-variable formulation space. A batched Bayesian search used each result to choose the next experiments and found photocatalyst mixtures six times more active than the starting formulations. Every completed experiment changed what the system did next. The robot optimized within a goal and search space that humans had already chosen. It did not decide which scientific question mattered. So what this work demonstrates is narrower, but still useful: a search history pays off when the options return standardized outcomes quickly. Open-ended biology is harder because branches can take weeks and the discarded alternatives may never be run. Some exploration therefore has to be bought. Where two branches are plausible and the stakes justify the cost, a lab should sometimes run the runner-up. Otherwise the record captures what today’s scientists usually chose and stays silent on what they systematically overlooked. A funder could ring-fence a small fraction of a grant for the branch not taken, provided that the decision record and the outcome are both deposited. That costs money, but so does having every lab rediscover the same abandoned path. Test whether taste transfers When it comes time to evaluate if our new AI system exhibits taste, the comparison should run across laboratories and fields. At selected decision points in a live research campaign, we should freeze the six fields: the evidence, the candidates, expected results, confidence, costs and the choice made. Experts then rank the options before the outcomes are known, and those outcomes are checked independently later. We could give models one of two diets - papers alone, or papers plus decision histories - and ask them to rank the next experiment on unfamiliar projects. Then, we score information gained per dollar and week, calibration, and how quickly weak branches are abandoned. If histories improve choices only inside the lab that produced them, they amount to useful organizational memory. If they improve choices on unfamiliar problems elsewhere, Alasdair’s group will have captured something science has never managed to write down: a transferable record of taste. Until that happens, a scientific search history is a promising record, not yet a training set.
Arab AI Slop and the Precarious Politics of Digital Kitsch
As Israel’s genocide in Gaza and the subsequent regional war reshape the Arab internet, AI-generated slop has emerged as a new form of digital kitsch and political fantasy fueled by precarious labor.
AMGEN TO OPEN NEW SCIENCE & INNOVATION CENTER IN GENOME VALLEY, HYDERABAD
/PRNewswire/ -- Amgen (NASDAQ: AMGN) today announced plans to open a new Science and Innovation Center at Genome Valley in Hyderabad. The center will join...
Geno Smith gives worrisome flashbacks with ugly Jets practice
It was easy to believe it was 2014.
Scientific advancement has never been more prolific—so why has trust in science plummeted?
From genome editing to quantum computing, scientific progress is accelerating at an unprecedented pace, yet public faith in science is collapsing. Our species has mapped the human genome, created powerful ...
UNC researchers are using Palantir to build a massive collection of health data
The data collected so far “includes more than 535,000 whole genome sequences.”
Accelerating life science computing with AI-ready infrastructure
Discover how computing is transforming life science research through AI infrastructure, GPU acceleration, and genomics.
Honoring Indigenous Midwives: Recognizing Indigenous Women’s Role in Delivering Family and Community Healthcare Across the World
Indigenous midwives provide trusted maternal and community healthcare, preserving ancestral knowledge while supporting families. Growing recognition, training, and integration into health systems are improving outcomes for women and children worldwide.
War, Erasure, and the Politics of Culture in Sudan - Georgetown Journal of International Affairs
Two millennia of inhabitation by indigenous groups, immigrant and diaspora communities, and many others who made the land their home have shaped Sudan’s cultural legacy along the two Niles. Today, over 120 languages connect Sudan’s territories and diasporas, exemplifying the country’s immense diversity as the result of its complex history. However, contemporary legislation, such as […]
Dr. Abdul El-Sayed on Historic Michigan Win: “People Are Sick and Tired of This Politics of Hatred”
We speak with Dr. Abdul El-Sayed after his victory in Michigan’s primary race for U.S. Senate sent shockwaves through the Democratic Party. El-Sayed, a former public health official, ran a progressive campaign focused on affordability, Medicare for All, getting money out of politics, and opposing Israel’s genocide in Gaza. He defeated Congressmember Haley Stevens, who was backed by tens of millions in outside spending including by AIPAC, the powerful pro-Israel lobby group. “In an era where many of us can’t afford basic things like groceries or rent or healthcare, the idea that your government is sending your tax dollars to buy bombs and tanks for foreign governments seems anathema,” El-Sayed says. “That money could be spent to fix your potholes, rebuild your kid’s school.” El-Sayed says his focus now is on beating Republican nominee Mike Rogers, whom he calls a “bootlicker for Trumpism,” and to present a positive vision for his party that can lead into the next Democratic presidential administration.
This A.I. Just Created Viruses Not Found in Nature
Scientists trained artificial intelligence on libraries of DNA and then asked the model to create recipes for viral genomes. Sixteen of them were viable, yielding new viruses.
Butterfly lilies wing their way to Science
Many animals and plants show left-right differences in how their bodies or organs are arranged, but we still know little about how such asymmetries evolve or how genes control them in natural populations. Mirror-image flowers, in which female and male sex organs are deflected to opposite sides in left- and right-handed forms, provide a notable example of such asymmetry. Here, we studied South African butterfly lilies, where individual plants produce only left- or right-handed flowers. Their mirror-image flowers promote outcrossing by depositing pollen from each floral form onto a specific region of a pollinator’s body that matches the stigma position of the opposite form. This suggests that selection for efficient pollen transfer between forms maintains this natural polymorphism. Our work uncovers a hemizygous supergene that coordinates the left-right orientation of female and male sex organs in mirror-image flowers by linking two independently acting genes for style and stamen handedness in a single, nonrecombining genomic segment. This architecture ensures the coinheritance of a matched pair of organ orientations that is essential for efficient cross-pollination between floral forms. At the developmental level, we show that floral handedness emerges from the interaction between an intrinsic tissue chirality and a gravitropic response that orients the style and median stamen relative to gravity. Together, these findings reveal how a supergene, hormone and microRNA signaling, tissue chirality, and an external physical cue combine to produce and maintain a stable left-right polymorphism in natural plant populations.
AI designs a novel E. coli killer
Using an AI model of their own creation that writes whole genomes, a team of Stanford scientists has engineered a novel bacteria-fighting phage. A new age of antibiotics could be on the horizon.
Strange DNA Structures Found in The Human Genome Go Beyond The Double Helix
“We now have a complete picture."
Strange DNA Structures Found in The Human Genome Go Beyond The Double Helix
“We now have a complete picture."
Honouring Guatemala’s Indigenous midwives and making space for Indigenous health systems
Guatemala’s Indigenous midwives won recognition of their work before the Constitutional Court. Seven years on, UN Human Rights has documented that the ruling still has not reached the health services where they work every day. This year’s International Day of the World’s Indigenous Peoples is dedicated to them.
Geno Segers will no longer join Broadway’s ‘Hadestown’ after online backlash
The actor and producers say they mutually agreed to part ways following criticism over past comments about transgender people. “Hadestown”
If Not AOC, Then Who?
What do we do if Alexandria Ocasio-Cortez decides not to run for president in 2028? It makes sense that many leftists are currently focused on calling on her to take the plunge. But the absence of a Plan B, or even much discussion about one, is worrisome. The US Left can’t afford to sit out the 2028 Democratic primary. Doing so in 2024 was a disaster: our abstention self-marginalized anti-billionaire politics from the national conversation and thereby gave space for Harris to pivot to the “center” (i.e. the policy preferences of corporate donors, establishment hacks, and AIPAC). Abstaining again in 2028 would be especially counterproductive since democratic socialists now have so much wind in our sails after our big electoral wins in NYC and across the country. It’s time to deepen our momentum, organization, and profile — not to retreat to the margins during America’s single most important political battle. Even more urgently, keeping Trump’s heir out of the White House may depend on whether leftists and the party’s unprecedentedly disenchanted base can force the Democrats in 2028 to take meaningful steps towards a very angry electorate and away from the corporate-consultant blob that has helped get us into this mess. If AOC (or Abdul El-Sayed) decides to run, we should enthusiastically go all in — DSA, fighting unions, progressive organizations, anybody who wants to see a better country and world. But, as far as I can tell from the outside, there’s a real chance that she doesn’t run. And we can’t just wait and see where she lands before discussing alternatives, since AOC’s decision might not come for quite a while, giving us little time to scramble at the last minute for an alternative. So we should start working now on getting a Plan B into motion, and recruiting a good candidate for the role. Here’s one idea. A Worker Candidate — Healthcare Not Warfare 2028 Run a union worker Leftists don’t need to always run experienced, well-known socialist politicians for high-profile contests. Lula, the current president of Brazil, began his political career as a metalworker militant who ran for governor of São Paulo in 1982. Especially in an era of institutional distrust, it’s possible to lean hard into making a virtue out of a working-class comrade’s distance from traditional politics. Experience abroad shows this clearly. Rachel Kéké — an immigrant hotel housekeeper — ran as the candidate of the leftist La France Insoumise for the National Assembly in 2022, defeating a former minister in the Macron government. The Belgian Workers’ Party in 2024 won its first Flemish seat in the European Parliament by running Rudi Kennes, a three-decade veteran of the Opel Antwerp auto factory. And the South Korean left in 2024 elected auto factory militant Yoon Jong-oh to the National Assembly. If a tiny French Trotskyist organization could make such a big splash in 2002 and 2007 by running a well-spoken postal worker cadre for office — the LCR’s Olivier Besancenot received about 1.5 million first-round votes — it’s not far-fetched to expect that a much larger organization like DSA, together with a broader coalition of the willing, could run this playbook to much greater effect. This is especially the case now that almost everything DSA does immediately becomes a national news story. We don’t need someone famous. We just need a charismatic, well-vetted comrade who works in a relatable working-class occupation — e.g. a nurse, or a worker in auto or construction, or at Amazon. Ideally, they have a compelling personal story or have been part of a significant strike or organizing campaign, but even those criteria don’t necessarily have to be deal-breakers. The main lesson of the Graham Platner fiasco isn’t that we should never run outsiders for office (the momentum he generated proves the exact opposite), but that they need proper vetting and roots in democratic membership organizations like DSA or a union. In any case, there are plenty of ways to signal working-class authenticity without resorting to Platner’s or Fetterman’s performative macho white dude affect. Better to have someone of any gender or race who is actually working class, with firm socialist politics, who can speak from experience about the day-to-day realities of trying to make it in America. There are surely at least a dozen such worker leaders in our movement nationwide; we just need to sit down and convince one that their personal sacrifice for the greater good (i.e. running for president) will be worth it. If we don’t have a frontrunner with a clear path to victory like AOC (or El-Sayed, were he to win Michigan), it’s better to embrace someone whose decision to run in itself tells an important story about US politics: workers have been iced out of our political system and are now fighting hard to break back in. The novelty factor, in itself, would generate press. And it would help democratic socialists signal to the American public that our movement’s defining characteristic is that we represent workers vs. bosses, not that we’re “the furthest left” force in American politics — a framework that suggests we’re extremists and that helps our opponents isolate us from non-college-educated voters by highlighting extremely minoritarian (and misguided) stances included in DSA’s platform like prison abolition. We don’t get many opportunities to speak to tens of millions of Americans; we need to use these opportunities to broaden our appeal beyond those already in our orbit. Run to polarize the 2028 primary and general election around “Medicare for All” and “End All Aid to Israel” Why should democratic socialists use our scarce time and volunteer energy to run in a race we’re unlikely to win? Running in the 2028 primary will not only recruit us scores of members (imagine having a DSA member intervening in eleven nationally televised primary debates!), but — more importantly — it has the potential to be a decisive leap forward towards an America that finally starts meeting the needs of working people instead of HMO and AIPAC billionaire donors. Polarizing litmus tests are good, actually — as long as they’re fought for around popular demands in a thoughtful and strategic way. Democratic socialists have an opportunity and responsibility to make the 2028 primary about two of the most widely and deeply felt issues of our moment: domestically, America’s unaffordable, family-breaking private healthcare system; internationally, America’s bankrolling of the genocidal Israeli government. A candidacy relentlessly demanding Medicare for All and No Aid to Israel would pose a sharp question to the American public, the Democratic Party, and other 2028 contenders: Why can’t working-class Americans afford their healthcare bills at the same time that our government is spending at least $3.8 billion yearly to fund an Israeli regime eager to keep dragging us and the world into more forever wars? Our candidate can agitate around a clear message: I’m running to give voice to all those working-class Americans who are struggling to get by. No matter what state you live in, who you voted for in 2024, or your background, it’s just plain common sense that we should make healthcare more affordable instead of spending billions to enable the Israeli government’s crimes against humanity. Every American who agrees with me when I say ‘Medicare for All — Not a Dime for Israel’ should make their voice heard through our campaign. Racking up a high number of votes for this agenda is a crucial way to show the Democratic Party and the country as a whole that we can’t keep supporting a life-destroying status quo in our healthcare system and in the Middle East. If we want to defeat Trump’s handpicked crony this coming November, we need to speak to ordinary people’s frustrations with the status quo — we can’t keep running the same tired establishment playbook and expecting a different result. For those highly engaged voters (or skeptical media pundits) who raise concerns about wasting votes, the candidate can take the time to explain why this isn’t the case: It's true I'm a long shot. But Zohran showed anything can happen — and voting for me is a pragmatic decision, not a wasted vote. In a heavily divided primary with a large number of candidates and a very discredited establishment, my campaign and the democratic socialist movement I’m part of are positioned to be the balance of power if we can get a large enough number of voters to loudly demand Healthcare Not Warfare. Since there’s a high chance no candidate will get to 50% in the 2028 primaries, the Democrats could very well be heading towards a brokered convention, where a disciplined, principled current committed to breaking from corporate donors can play an outsized role in making sure whoever ends up with the nomination raises the banner of single-payer healthcare and cutting aid to Israel. How exactly could running this sort of primary campaign be translated into actual leverage? The candidate replies: I’m aiming to win the nomination, but if I don’t achieve that goal, my delegates and I will pledge our support in the primary only for a candidate who agrees in the general election to call for ending US aid to Israel and establishing Medicare for All at home. These are both winning planks for November against the Republicans, and the only reason I can see that other candidates haven’t yet raised these is that they’re still more scared of the donor class than they are of the people. That needs to change. If Democratic leaders want young people, workers, and those sick of the status quo to show up in big numbers this November, they need to meet us halfway. In this way, whether or not we win the nomination, democratic socialists could still play a decisive role in 2028. The approach outlined here is similar to what radical left parties periodically do in parliamentary democracies like Denmark or Sweden when they find themselves as a junior partner electorally: they dictate to center-left allies what their terms would be for enabling, from the outside, the formation of a new government. Running a Healthcare Not Warfare candidate will make it significantly more likely that the 2028 Democratic candidate stands with ordinary people instead of donors on these two pivotal planks — a shift that will, in turn, make it easier to achieve the existentially important task of defeating MAGA’s heir in November. Look at how much popular traction the Uncommitted movement got with a similar strategy in 2024 with so little on-the-ground organization — surely we can go much further with a working-class candidate, a much bigger DSA, and a Democratic Party base that has turned against Israel, billionaires, and the hacks in the party who prop them up. Objections and Responses There are quite a few objections to this proposal, many of which are very reasonable. Let me briefly address each here. Socialists shouldn’t waste their scarce time and resources on a candidate unlikely to win. This is a good rule in general, but there are important exceptions, and presidential elections are the main one. There’s no other political contest that gets anything like this level of attention and engagement in the US, so if you want to be a serious force in nationwide politics, you basically can’t afford not to have a candidate. Far from being an overall drain on our resources, running a dynamic 2028 campaign would likely result in a major net increase in members and capacity. In that spirit, the very pragmatic Milwaukee sewer socialists — who mostly ran to win at home in Wisconsin — supported Eugene Debs’s propagandistic presidential campaigns, which they correctly saw as a crucial means of recruiting to the Socialist Party. And now that the (post-1972) Democratic Party gives more weight to voters than party operatives in determining its presidential nomination, it’s become feasible to run as a socialist in primaries without risking a split in the vote against the Republicans in November. We should just support Ro Khanna, who also supports M4A and ending aid to Israel. I like Ro Khanna and would enthusiastically vote and canvass for him for president were he to get the nomination. But there’s a real chance that Khanna’s bid for office doesn’t catch on; he lacks the grassroots organizational apparatus of DSA, and, because he’s not really of the Left or labor (despite his current very good positions), he’s unlikely to generate the type of buy-in and enthusiasm that a DSA candidate would. Moreover, Khanna would be running as an individual, not as someone emerging from and building an organized movement — his campaign would not likely focus on building sustained power from below, nor would it likely polarize the 2028 primary around M4A and Israel aid. Also, and not inconsequentially, the poor electoral results for Tom Steyer and Saikat Chakrabarti this spring suggest that there’s perhaps not much of a popular appetite in the Democrats’ base to support multi-millionaire class traitors. Much better, then, to run a democratic socialist worker. If by Super Tuesday it’s clear that our campaign has captured the main left lane in the primary, Khanna should drop out and endorse us; conversely, if he’s managed to capture this lane, DSA could at that point transform its Healthcare Not Warfare campaign into an independent campaign to elect Ro Khanna focused on winning (and holding him accountable to) those two critical planks. An openness to consolidating an anti-corporate candidate by Super Tuesday is a necessary component of the strategy I’m proposing, because otherwise we risk splitting the primary votes (per DNC rules, you need at least 15% to get any delegates to convention). We should convince Shawn Fain or Sara Nelson to run for president instead. I agree it’d be great if either ran for president, but my impression is that there’s basically no chance that will happen in 2028, because both are firmly focused on their union leadership duties (and, in the case of Fain, beating back a federal witch-hunt). This plan could have DSA end up endorsing a non-socialist, non-DSAer for president. That’s against our principles. It’s a myth, and bad politics, that socialists can’t ever support candidates who aren’t members of their organization and/or who don’t call themselves socialists. Bernie, after all, was not a DSAer. And socialists abroad regularly make tactical decisions about if and when supporting a non-socialist candidate makes sense from the standpoint of promoting working-class interests, defending democracy, and building a socialist current in the process. If your “principles” prevent you and DSA from helping achieve the momentous stride forward of having a Democratic candidate in 2028 run on Medicare for All and ending aid to Israel, those “principles” are not very good. In fact, they actively undermine the causes they’re aiming to support. We shouldn’t confuse principles (working-class independence) with tactics (the best way to advance this in a given context). In my recent article in Catalyst on Milwaukee sewer socialism (I’ve uploaded the full text here), I have a section showing how similarly rigid rules about endorsements had to be eventually discarded in the old Socialist Party nationwide after WWI because they tended to lead socialists towards a sectarian abstention from broader anti-corporate electoral insurgencies beyond their party’s control. For what it’s worth, Lenin’s current under Tsarism frequently backed bourgeois candidates in the second round of elections and Lenin himself advocated that British Communists support Labour Party candidates; for his part, Kautsky in 1912 defended the German Social Democracy’s electoral pact with the Progressives in the runoffs. If our predecessors could be that tactically flexible in an era before the limits of their underlying strategic assumptions about intransigent class politics in capitalist democracies were made clear, then there’s no need to insist on being more tactically rigid today, after a century’s worth of accumulated experience. As long as you maintain your own political profile and organization while engaging in broader coalitional efforts, there’s zero inherent contradiction with the principle of political independence. More specifically: DSA and allied organizations should enthusiastically back Michigan’s Abdul El-Sayed if AOC declines to run and he throws his hat in the presidential ring. (I have no idea whether he’s even considering this path, but there’ll surely be chatter about it if he wins his Senate race this November.) Though he doesn’t call himself a socialist, El-Sayed is a principled Berniecrat, a consistent fighter for Palestine, and would have a clear path to victory. Using the “s” word is far less important than whether a campaign fights for the interests of working people at home and abroad — and whether actively participating in it can grow the organized working class and the Left. And the same holds true if a less anti-corporate candidate were, under pressure, to adopt our two Healthcare Not Warfare planks. Why focus only on M4A and ending US aid to Israel? There are so many other important issues to fight for! Obviously there are many pivotal issues beyond healthcare and Israel, and our candidate — and especially our organizations involved in the campaign — should be prepared to speak on all of these. But one of the crucial lessons of the Zohran campaign is that you have to relentlessly stay on message if you want to cut through the noise. CNN and Fox News will want to talk about DSA’s views on Venezuela and abolishing the police; we need to polarize the debate on the widely and deeply felt issues that are most favorable for growing the Left, isolating our opponents, and winning urgently needed changes. One recent poll found 63% of Americans support M4A, even after respondents were told it would raise taxes and eliminate most private insurance. Another found that 74% of Democrats opposed “providing additional economic and military support to Israel.” And focusing on two demands sets the campaign up to be able to leverage its mandate to make clear demands upon other candidates (which we can’t do if we run with a laundry list of demands). Talking about a Plan B is a distraction from the more urgent work of building a groundswell of calls on AOC to run. It’s good for DSAers, fightback unionists, and progressive organizations to try to convince AOC to run. This proposal is meant as an addendum to pushes to get AOC to run and to line DSA up for that eventuality, not as a substitute for those efforts. But I’m worried that, like in 2024, we might eventually find ourselves with no time to find a viable alternative unless we start now. DSA, with its abundant deliberative processes, moves slowly. The approach you’re suggesting seems risky. If a DSA candidate runs but doesn’t receive a lot of votes, it’ll undercut our current national momentum. This is a reasonable worry. All big initiatives always carry risks, and the path I’m advocating is certainly not free of these. That said, if a Healthcare Not Warfare campaign doesn’t catch on like we envisioned, it’s a pretty simple pivot in March 2028 to explain that in the future we really need our standard-bearers like AOC, or our growing bench of national electeds, to step up in presidential primaries. Moreover, it’s worth noting that the risk of my Plan B proposal is on the whole significantly less than the risk entailed by an AOC run. We should all back her if she runs, since she’d fire up the base, provide huge openings for organizing, have a real shot at defeating a Republican (especially given MAGA’s unpopularity), be a great standard-bearer for our issues, particularly M4A and ending aid to Israel, and be less willing than mainstream candidates to capitulate to any anti-democratic machinations from Trump and co. But it’s also true that AOC could lose, which would be a devastating setback to the country and the Left. Or she could win and find herself unable to pass much, if any, of her (and our) program, a demoralizing prospect. So if we’re willing to take these risks with AOC (and we should), it follows that we should be able to take lower-level risks if she doesn’t throw her hat in the ring. What’s Your Plan B? The US Left is facing its biggest opening for growth and influence since the 1930s. Initiatives that would have been impossible a few months ago are now potentially feasible. A President AOC is now easier to imagine, but if she ultimately assesses that the risks aren’t worth the potential reward in 2028, we can’t be left flat-footed. So even if you’re not convinced by the specifics of my Plan B, I hope you can at least agree that it’d be a disaster for us not to have one — and not to start getting a Plan B into motion. Hopefully other organizers and political currents will put forward their responses and alternative ideas ASAP. The stakes are too high to just wait and see. More As always, please share this article widely. This newsletter depends on all you lovely people to get the word out. Thank you! I uploaded the full text of my Catalyst article on Milwaukee sewer socialism here (it’s updated and 3x as long as the version published earlier on this substack). If you haven’t yet, please make sure to subscribe to Catalyst here; I read every issue front to back, highly recommend. 🌹🎵 Ivan Lins (arranged by Arthur Verocai) — “General da Banda” 🌹🎵
Hades, King Herod and the Politics of Theater. A Starry August. Stageworthy News of the Week.
The producers of “Hadestown” on Broadway rescinded the casting of Geno Segers as Hades, after OnStageBlog reposted Segers’ (now deleted) videos on social media that belittled transgender people. Th…
Brazil uses forensic science to trace gold's origin and tackle illegal mining in the Amazon
Brazil is using forensic science to tackle illegal gold mining in the Amazon, a top threat to the rainforest, Indigenous groups and other communities there that has accelerated deforestation and driven mercury contamination to dangerous levels. The work takes place at the National Institute of Criminalistics in Brasilia, the country's…
My Journey Into Researching Historical Erasure on Public Lands
Most people know me for my work on ocean conservation, Indigenous-led stewardship, and marine protected areas. Over the past year, however, I have found myself increasingly drawn into a different b…
Everyone alive may carry DNA from a ‘ghost lineage’ of human ancestors
Scientists analyzing modern genomes may have found a long-lost branch of the human family tree
Jets insider makes Geno Smith's biggest responsibility crystal clear
Geno Smith must prove the Jets' offense won't resemble last season's disappointing unit.
UConn Coach Geno Auriemma Joins 'Sportico Sports Business'
Geno Auriemma discusses the dramatic change in sports over the last 40 years, UConn's basketball success, the process of documentary filming and more.
Mamdani and Netanyahu Are in a Vicious War of Words
Mamdani has accused Netanyahu of committing genocide while the prime minister claims the mayor is “fomenting hate.”
Cuban president accuses US of 'political genocide' on anniversary of revolution
Cuban President Miguel Diaz-Canel issued a sharp condemnation of Washington's oil embargo and hardened sanctions in a speech on Sunday, calling the policy of U.S. President Donald Trump's administration "political genocide."
Brazil uses forensic science to trace gold's origin and tackle illegal mining in the Amazon
BRASILIA, Brazil (AP) — Brazil is using forensic science to tackle illegal gold mining in the Amazon, a top threat to the rainforest, Indigenous groups and other communities there that has accelerated deforestation and driven mercury contamination to dangerous levels.
Brazil uses forensic science to trace gold’s origin and tackle illegal mining in the Amazon
BRASILIA, Brazil (AP) — Brazil is using forensic science to tackle illegal gold mining in the Amazon, a top threat to the rainforest, Indigenous groups and other communities there that has accelera…
For Yukon River residents, salmon shortages have health consequences
A dietary staple, salmon had — until recently — been the main source of protein for Indigenous people who live along the Interior Alaska river systems.
Great Barrier Reef microbiome mapped as researchers discover 500 bacterial species previously unknown to science
Research identifies 808,585 viral genomes belonging to what scientists estimate to be 362,802 different viruses
GOP senators unveil move to memorialize communism victims on CCP's doorstep amid Dem civil war: 'No tolerance'
The proposed memorial would sit across from the Chinese Embassy, forcing CCP officials to face victims of Mao Zedong's rule and the Uyghur genocide daily.
Mamdani says U.S. authorities should arrest Netanyahu as ‘architect of a horrific genocide’
The New York mayor has repeatedly denounced the Israeli leader despite criticism from other Democrats. He challenged the federal government to ensure that Netanyahu be tried for war crimes by the International Criminal Court.
Ex-Giants Draft Pick Considered Breakout Coach For Broncos
The post-Tom Coughlin New York Giants culture has been horrible, but Davis Webb evidently learned a thing or two. The Giants' third-round pick of the 2017 NFL Draft was named as a breakout coaching candidate, while serving as the Denver Broncos offensive coordinator under ex-Giants coordinator Sean Payton. Webb spent two tours with the Giants, initially backing up both Eli Manning and Geno Smith during the controversial 2017 season under Ben McAdoo.