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Politics: What Changing Political Tides Mean For Gaza
Israel is expanding its command of Gaza and now controls almost 70 percent of the tiny enclave that’s home to more than two million people.More than 1,100 Palestinians have been killed since the ceasefire between Israel and Hamas nearly a year ago. Some 73,000 Palestinians have been killed in total since Israel’s military offensive began after Hamas fighters killed 1,200 people on Oct. 7, 2023. Meanwhile, dozens of aid groups have been barred from operating in Gaza.Almost every Gazan is dealing with hunger, with 77 percent of the population facing high levels of food insecurity, according to the World Food Programme.So, what do these shifting lines of control mean for those in need? And how could changing political tides affect the situation?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.
Inside the WTA's Player Business Mentoring Programme fueling careers beyond tennis
Through WTA's Player Business Mentoring Programme, players are looking at life after tennis with clarity and confidence. In partnership with learning and development company, Give Learn, players are gaining exposure to respected business professionals and develop leadership, entrepreneurial and soft skills.
GPEI leadership in endemic countries: polio eradication and strengthening health systems go hand in hand
Last week, the Polio Oversight Board (POB) of the Global Polio Eradication Initiative (GPEI) met with programme and public health leaders in both Afghanistan
AB Science cuts three trials in pipeline reset
French biotech AB Science is discontinuing three masitinib trials as it concentrates its clinical resources on an ALS phase 3 programme and the early-stage development of AB8939 in acute myeloid leukaemia.
John Carmack responds to Id Software layoffs, admits Microsoft stewardship claim aging badly
The Doom and Quake programmer is saddened by this week’s news of layoffs…
Texas Theatre Leads the Future of Cinema with Hybrid Programming
Theatrical programmers from coast to coast draw inspiration from the Dallas landmark.
Roche ends two Huntington’s disease drug programmes after disappointing results
⏱️ 10 min read | Roche announced it is stopping development of two of its huntingtin-lowering ASO drugs, tominersen and RG6496. This marks a disappointing end to an important chapter in HD clinical research.
Hungary moves to overhaul university models banned from Horizon Europe
Hungary’s new government is aiming to overhaul the governance model of the institutions and universities that lost access to Horizon Europe and Erasmus+ funds “in a short timeframe,” according to Péter Horváth, the new state secretary for science policy and innovation. “As of today, the two non-university foundation-controlled institutions under my remit have been transformed,” he told Science|Business. “We hope the universities will follow and that this will be enough to satisfy the EU’s demands.”Under the previous government, led by Viktor Orbán and his Fidesz party, many academic and scientific institutions were restructured and made into special public trust foundations, with members strongly linked to the government given lifelong mandates and significant decision-making powers with little oversight. The European Commission deemed that this undermined academic freedom and transparency in the country, leading to a ban on 34 institutions in 2022, including 21 universities, which saw academics in Hungary lose access to Horizon Europe grants. The new Hungarian government, elected in May and led by Péter Magyar and his Tisza Party, has promised to dismantle this governance model and restore the institutions to EU programmes. As a result, the European Commission has promised to return access to the Erasmus+ education mobility programme, but so far no concrete agreement has been made on the Horizon Europe programme for research and innovation. Hungary has already made legislative changes in June to allow the institutions to be reformed and set a timeline for the implementation.The non-university foundations, which are mainly cultural centres such as the Foundation for Hungarian Culture or the Makovecz Campus Foundation, will all be dissolved by August 31 this year, a date tied to EU-set milestones that Hungary must meet to unlock frozen funds, with control transferred to relevant ministries. Meanwhile, the universities will have until 31 August 2027. For each university foundation, the government will set the dissolution date and the body to take over operations. There is no final decision on a permanent new model for the universities, according to Hungarian MEP Eszter Lakos, who is shadow rapporteur for the Horizon Europe specific programme, a separate piece of legislation detailing implementation rules for the EU’s next research programme, due to start in 2028. “The aim of the transition year is to settle this with [the universities], not to impose a model, and not to put them under state control,” she told Science|Business. “The goal is to give academic independence back to universities.”There are three models that are most likely to be implemented. One would be a return to a traditional, state-run model. Another could be a newer, more self-standing public institution. A third option would be a reformed version of the foundation models that meet EU standards. According to Lakos, the dismantling of the system put in place by the Orbán government is well underway and if all goes according to plan, Hungary could regain access to EU research money by the start of the next academic year in 2027. “I believe that the Hungarian government is doing the necessary changes so the universities could return as beneficiaries to Horizon from the next school year,” she said. In the meantime, “the universities, institutes and cultural assets carry on under proper public stewardship rather than a handful of unaccountable trustees,” said Lakos. The laws passed in June impose new safeguards: board terms are capped at four years and renewable only once, appointments are made through open competitions and sitting politicians cannot join joining these boards.It remains unclear whether a domestic science funding programme set up as a back-up scheme by the former government following the EU funding ban, called HU-rizon, could be continued. “This programme should never have had to have been established in the first place, but it has proven to be quite popular,” he said. “I am considering continuing this programme with a refined focus on helping international collaborations.”Re-organising the research network One of the first priorities for Horváth and his cabinet is to resolve questions over the future of the Hungarian Research Network, Hun-Ren. The network of academic institutes was taken away from the Hungarian Academy of Sciences in 2019 and turned into a quasi-private organisation, with similarities in its governance to the public trust foundations.Horváth and his team have consulted over 5,000 representatives from the network and the conclusion is broad unhappiness with the directors of all the institutes involved. “We have presented the results to the president and the chief executive of the network and this is currently being discussed,” Horváth said. The plan is to re-integrate the network back into the Academy of Sciences but in an improved way, “learning from mistakes of the past,” he added. The government also wants to reintegrate four humanities and social science research centres into the network that the previous government had transferred to Eötvös Loránd University. The transfer brought sharp criticism from the academic community, with a group of Hungarian research heads, including European Research Council grant recipients, sending an open letter to Orbán warning that the transfer would “cause historically significant harm to the entirety of Hungarian scientific life.” The transfer was “one of the biggest shames in Hungarian research in the past 20 years,” Horváth said. “We want to immediately re-integrate them back into the research network and to regain the trust of these institutions, because the way they were treated was really unfair.”Another pressing issue is the Élvonal Excellence Research and Talent Development Foundation, led by Nobel laureate Ferenc Krausz. The foundation signed a financing agreement with the former government earlier this year for a budget of over €730 million over the next five years. The goal is to create a world-class centre to attract top talent from abroad and to develop local researchers. But there was little transparency about this foundation, and news of its huge budget, which is nearly as much as Hungary’s entire research budget, caused a stir in the media following the recent elections. Another issue is that, as with the foundation boards of the institutes banned from Horizon Europe, there was little-to-no oversight of decisions led by Krausz. “It was an excellent idea but an unacceptable execution,” Horváth said of the foundation. “The fact that this is out of the Hungarian funding scheme, mostly concentrating on one person who decides on the budget is unacceptable for us.”The government plans to merge the centre with the National Research, Development and Innovation Office, the country’s R&D funding agency, with a reduced budget. Horváth is hopeful that Krausz will still be involved. The new government’s R&D goalsA phrase that crops up regularly during the discussion with Horváth is “democratic process.” The new state secretary is determined to involve Hungary’s research community in shaping future policies. This marks a departure from the previous government’s approach, and several people in Hungary’s research community have commented on the openness of the new government. In terms of concrete goals, Horváth and his team already have plans. He wants to create a new science fund in Hungary, based on the best practices of other European countries. The fund would not be tied to annual government budgets and would provide long-term, stable financing. “If we were to succeed in creating this fund, then I think it would be one of the biggest achievements for me in this period of government,” Horváth said. On the innovation side, he is looking into how best to bring in the private sector. “We want to make sure that we are working with the private sector to support innovation,” Horváth said. One of his big aims is to introduce entrepreneurship teaching into high schools. Hungary already has a reputable national academy offering research and innovation training in the field of natural sciences, and Horváth wants to expand this to all disciplines and across the whole country. “One of the main ways to elevate our innovative businesses is to teach our children to be innovative,” he said. “This will probably need ten years to pay off, but this is what we should do. Our aim is to make Hungary strong in our region, and this is what is needed.” Related articlesHungary’s Horizon Europe performance in numbersCommission unlocks Erasmus+ cash for Hungary, Horizon could be next‘Academic Huxit.’ Hungarian researchers speak out on impact of EU ban A more difficult task will be funding. The new government is aiming to increase research spending to 2% of the GDP by 2030, and then increase it to 3% in line with EU objectives. Currently, spending sits around 1.3%. But according to Horváth, the current budget, inherited from the previous government, is “heavily in the negative,” so any plans to increase research spending will have to start next year. Achieving 2% by 2030 already needs a big push, almost doubling the research budget. “This is something we’d definitely like to reach, and something I can see us achieving,” he said. “From the 2030s, I’d like to see an innovative generation growing up that can help us reach the 3% target.” Positivity in the new governmentDespite the many challenges facing Horváth and his team, the mood is positive. “It feels a bit like a start-up right now. Everyone is working 24/7, day and night, trying to do as much as they can. There is a lot of energy,” he said. It is a big change for the state secretary who, like many in his cabinet, is coming from a background in research or business, and not in politics. “Six weeks ago, I was sitting with my microscope and my research PhDs, so it’s been a big change for me,” said the computer scientist, who was previously the director of the Institute of Biochemistry at the Hun-Ren Biological Research Centre in Hungary and worked at the Institute for AI for Health at Helmholtz Munich. But he is relishing the task to transform the country’s R&D landscape. “We feel enormous support from the Hungarian people, but also from Europe,” he said. “We’ve received a lot of letters of support from around Europe. There is big trust there, and huge responsibility on our side. We want to get everything back on track, and there’s a lot to do.”
Olympic Q-Series sports programme confirmed for Tokyo, Shanghai, Montreal and Orlando
The sports programme for each stop of the Olympic Q-Series has been confirmed, with Tokyo, Shanghai, Montreal and Orlando set to stage a dynamic mix of team and individual sports on the road to the LA28 Olympic Games.
Delivery firm Evri sues BBC for £1.2m over Panorama documentary
Company seeks redress for contracts it says it has lost as a result of programme’s claims about its business practices
Moderna highlights expanding mRNA platform at Science Day
Moderna's Horizon programme contains a variety of mRNA assets in varying stages of development, including a preclinical in vivo candidate.
Project ASCENT at ILL selected for EU funding under "Choose Europe for Science"
The Institut Laue-Langevin (ILL) will lead the ASCENT project, funded at 1.4 M€ by the European Commission as part of the initiative "Choose Europe for Science 2025". The goal is to train the next generation of researchers and sustain Europe’s leadership in neutron science. ASCENT is one of 16 projects (three of them in France) funded under the pilot call of a programme that aims to enhance the attractiveness of research careers in Europe and address the challenge of scientific talent retention. It is also the only project led by a large-scale infrastructure.
MIP participates in online lecture on the ICTY for Munich students of international law and politics
On 22 June, the Mechanism Information Programme for Affected Communities (MIP) participated online in a session titled “The ICTY: Structures, Legal Significance and Political and Societal Perspectives in the Region and Serbia,” organised by Universität der Bundeswehr München as part of its Academic and Research Trip to Belgrade. The event took place at the Goethe‑Institute Belgrade and was attended by 20 master’s students and four faculty members from the graduate specialisation programme International Law and Politics.
Cunard strengthens entertainment partnerships
Cunard announces 2027 entertainment programme with four Event Voyages on Queen Mary 2 and new Entertainment Residencies across fleet.
Don’t worry, a politician can’t present the Today programme. Michael Grade is wrong about that
As the former Ofcom chair says extraordinary things about the rightwing channel and its critics, a factcheck would not go amiss, say Stewart Purvis and Chris Banatvala, both formerly of Ofcom
Bukayo Saka misses England training
The Arsenal winger worked indoors on an individual programme and is expected to be available, but Noni Madueke is likely to keep his starting place.Photo by Charlotte Wilson/Getty ImagesBukayo Saka mi...
Could China make a sea-skimming hypersonic missile a real nightmare for the US?
The country’s top science institute is launching a research programme into the technology that might one day underpin such a weapon.
WHO Step-by-Step programme recognized as a promising innovation for mental health in humanitarian settings
WHO, in collaboration with the Pan American Health Organization (PAHO) and Lebanon’s National Mental Health Programme, showcased Step-by-Step at the World Bank Group’s biennial Fragility Forum in Washington, DC. The forum convened more than 1500 representatives from governments, international organizations and civil society to advance the development agenda in the world’s most fragile and crisis-affected communities. WHO was invited to demonstrate Step-by-Step – a digital self-help intervention for depression, alongside innovations presented by Stanford University and Google. The World Bank Group selected Step-by-Step from among more than 50 innovations that they reviewed in the lead up to the Forum.About Step-by-StepStep-by-Step is a free digital tool developed by WHO in collaboration with Lebanon’s National Mental Health Programme and other partners, that helps people manage depression and anxiety on their own, with light guidance from a trained supporter. It uses a picture-based story to walk users through evidence-based techniques for managing common mental health conditions. Users complete five modules, with weekly contacts – of around 15 minutes each – from a trained non-specialist helper, such as a community health worker.Evidence-basedClinical trials in Lebanon involving nearly 1250 participants – including 680 Lebanese participants and 569 Syrian participants – showed that Step-by-Step significantly reduced depression, anxiety and stress, and improved daily functioning. By the end of the programme, a reduction in depressive symptoms of more than 50% was reported by almost half (46%) of Lebanese participants and more than one third (37%) of Syrian participants compared to approximately 14% of those who did not use the programme. Cost-effectiveness analyses further suggest that Step-by-Step may offer a cost-saving response to depression in humanitarian emergencies in low- and middle-income countries.Used globallyStep-by-Step is already in use nationwide in Lebanon and Thailand, as part of each country’s mental health system. In India, the NGO – Kaya Guides – has adapted Step-by-Step for delivery through a widely used messaging app. Together, these programmes have provided thousands of people with evidence-based support for depression. The content is freely available from the WHO website for any organization or country to adapt for their own context.A new implementation guideThe Fragility Forum coincided with the recent launch of WHO’s new practical guide: Psychological self-help interventions: delivering self-help for individuals, featuring Step-by-Step and Doing What Matters in Times of Stress (WHO, 2026). The guide is designed to help governments, health workers, organizations and planners bring evidence-based mental health support to more people, particularly in low-resource and crisis-affected settings.
Latvia pilots citizen engagement in research grant evaluations
Latvia has introduced an element of citizen engagement to the evaluation of nationally funded research grants. The aim is to both create more connections between science and society, and to improve the quality of its evaluations. The move comes as research funders across Europe are experimenting with ways to improve evaluation processes in the face of a sharpened focus on science’s impact on society. Evaluators of grant applications submitted to Latvia’s Fundamental and Applied Research Programme (FLPP), the country’s main research funder, will this year have the option of consulting citizen feedback on challenges the public thinks science should focus on to inform their decisions. “In recent years, both public discussions and policy-level debates in Latvia have highlighted the importance of demonstrating how publicly funded research contributes to society, the economy and the resolution of real-world challenges,” said a source at the Latvian Council of Science (LCS), which manages the FLPP. “At the same time, research institutions themselves expressed interest in improving the project evaluation framework while continuing to ensure that funding is awarded to the highest-quality projects,” the source added. The citizen input comes from a survey that was conducted between 25 February and 16 March 2025, to which 1,737 people responded. It gathered information on what the public views as problem areas for Latvia, and the role of science and technology in providing solutions to these problems. A summary of these responses has been included as an annex to the FLPP 2026 call for proposals that evaluators can refer to, purely in an advisory manner, when judging proposals. Results from the survey show that the main problem areas identified by the public were in healthcare and public health, followed by the development of new treatment methods and medicines, and then digital technology, data security and cyber security. At the bottom of the list was research aimed at acquiring new knowledge about the universe, matter and the laws of nature. Further analysis looked at the public view of the possible role of science in solving these problems. The survey charted 4,167 individual responses based on open-ended questions that were derived from the participants’ answers. The analysis again found that medical and health sciences topped the scoring, with 788 responses referring to the field. Humanities and the arts were bottom of the list, with 625. Digging further into the details, the survey suggests citizens are aware of and concerned about a number of research areas. This includes technologies and innovation to improve the environment or reduce pollution, the development of modern military technologies and cybersecurity tools, and the development and application of artificial intelligence, among others. “We hope this initiative will help strengthen public trust in science and create a more meaningful dialogue between researchers and society,” the LCS source said, adding that it offers benefits to researchers, evaluators and to the general public. More space for citizen engagement in evaluationsThere is a gradual but increasing use of citizen engagement in research evaluation processes around Europe, especially in healthcare, but it remains relatively rare, said Henry Sauermann, a professor at the European School of Management and Technology in Berlin and an expert in citizen science.“Given that we are at a point where citizen involvement is extremely limited, there is presumably space for more, but it's not that we should do it just because we want to do it,” he told Science|Business. He said some research lends itself better to having citizen input, and this usually tends to be on the applied end of the science spectrum where the public can offer useful feedback based on their experiences. He added that advising scientists on certain topics to study is also a useful approach, in the way that Latvia is doing. “The public does fund a lot of science, there's a lot of tax money going into this. We of course do want to preserve academic freedom, but it's also not unreasonable to incorporate more feedback or input from citizens where possible,” he said. Related articlesCitizen science: where, when, and how to let the public contribute to researchHow can Europe cope with a flood of AI-assisted research grant proposals?Data Corner: Horizon Europe’s AI, digital and data call success rate is 5.2%There are several ways of involving citizens in science funding. The most minimal way is having a few representatives on a panel, such as members of a patient group or union. The most direct way is crowdsourcing funding for specific projects. There is an increasing number of online platforms that allow the public to chip in to support scientific proposals.Sauermann studied this in a recent paper and found that it can have its uses, but it still is not clear if there are benefits to it. There are various assumptions linked to citizen engagement, for example that it increases public trust in science, or that it provides a representative view of what the public thinks about science. These are not necessarily true, Sauermann found. People who participate in engagement activities tend to already be very trusting of science, and, on the whole, it is generally the well-off and well educated who contribute, giving a narrow view of public opinion. On whether citizen input can help manage the increasing number of proposals that are being submitted due to assistance from AI, Sauermann is more sceptical. “The obvious answer to the flood of AI-written proposals is AI-driven evaluation,” he said, adding that it doesn’t mean citizen engagement shouldn’t be a part of evaluations in a well thought-out manner. Southern Denmark’s successful approachOne successful example of citizen engagement in science evaluations was implemented in southern Denmark. Between 2019 and 2025, citizens in the region were invited to vote to fund one of five pre-selected projects in the field of healthcare. The project, called A Healthier Southern Denmark, was a collaboration between regional authorities, the University of Southern Denmark, and two media partners. Over the seven years, there were 75,000 votes and significant public engagement online and on social media. “It was a bit of a wild project, we’d never done something like that before and we were a bit nervous about what would be said in the media about it. But actually, people were very positive,” said Anne Kathrine Overgaard, one of the main organisers of the project from the University of Southern Denmark. The university and its researchers have learned a lot from the experience, particularly about engaging with society and shaping their research to match real-world needs. This is important with Europe’s increasing focus on competitiveness and bringing innovations to market faster, Overgaard said. She hopes to see more citizen engagement in evaluation processes and in science more broadly. “For many years, citizen engagement has been a bit of an add-on to proposals, just to check a box. But I think things are changing,” she said. It’s less about citizens just gathering data and more “about the dialogue between the public and the scientists,” she said. The initiative ended last year as the team wanted to regroup to find fresh momentum. The development of AI and AI-written proposals has made Overgaard reflect on how the project could be reworked to help evaluators. She hopes to bring it back in the future. “It could be a good idea to try this initiative again in a slightly re-worked format,” she said.
‘Unbelievable’ waste and inefficiency at MoD, says ex-defence minister Al Carns
Exclusive: Carns, who quit last week, says he was angered by unwillingness to confront sunk costs of legacy programmes
Community wellbeing programme launches in Truro for residents
Sessions will focus on areas including physical health, emotional wellbeing and stress management.
Rejuvenate Bio and Merck Animal Health Join Forces on Novel Animal Health Gene Therapy Programme
Rejuvenate Bio and Merck Animal Health Join Forces on Novel Animal Health Gene Therapy Programme
WHO urges targeted action to strengthen emergency workforce capacities for shared health risks across the Asia-Pacific region
At a time when the world is more interconnected than ever, the World Health Organization (WHO) is disseminating a comprehensive regional analysis of shared health risks across Asia and the Pacific, urging Member States to invest in enhancing workforce capacities regionwide to mitigate these risks and ensure health systems are better prepared to anticipate, tackle and withstand a range of crises and shocks. Over 100 delegates from 49 countries and areas in the Asia-Pacific region reviewed results from the regional risk analysis during the WHO-led Asia Pacific Health Security Action Framework (APHSAF) Stakeholders Meeting in Malaysia. Synthesizing insights from 21 strategic risk assessments and more than 800 multisectoral experts, the regional analysis highlighted an urgent imperative: countries must proactively invest in emergency workforce preparedness to navigate a landscape where climate hazards, disease outbreaks and geophysical events increasingly overlap. These complex converging crises create devastating, compounding impacts on health systems and communities – reiterating the need for investing in a fit-for-purpose regional health workforce and multisectoral action.Key findings: an evolving risk landscape More than half of the participating countries ranked flooding, cyclones, dengue and pandemic-potential respiratory pathogens as being of high or very high risk, while antimicrobial resistance, landslides and gastroenteritis remain widespread concerns as well. “Given that 51% – over half – of these assessed hazards are deeply interconnected, isolated health interventions are no longer sufficient,” said Dr Saia Ma’u Piukala, WHO Regional Director for the Western Pacific. “Extreme weather events like cyclones and floods directly trigger subsequent disease outbreaks, while environmental degradation – driven by sea-level rise, coastal erosion and saltwater intrusion – fuels health risks across the Pacific. Mitigating these cascading risks requires unified, cross-sectoral action linking environmental, agricultural and public health policies to build true regional resilience.” Priority recommendations for action To address critical vulnerabilities, WHO calls on Member States in the Asia-Pacific region to urgently prioritize the following strategic actions: Bridge workforce capacity gaps. Embed and standardize emergency preparedness within academia to promote regional workforce interoperability. Foster multisectoral coordination. Address ad-hoc taskforce responses and fragmented surge support through formalized contingency plans and standard operating procedures that are frequently updated and tested. Secure sustainable financing for emergencies. Overcome systemic barriers to access dedicated funding for both immediate anticipatory actions and long-term emergency preparedness initiatives. Enable emergency-ready primary health care. Embed emergency management into public health workforce readiness planning. Ensure that emergency planning is inclusive. Establish clear pathways for inclusive emergency planning that actively involves communities most at risk and other vulnerable groups. Optimize communication. Update risk communication and community engagement strategies, aligning them with seasonal risk calendars. Elevating workforce readiness to meet regional health risks While the gaps identified are significant, the Asia-Pacific region possesses solid foundational pillars, including dedicated clinicians, laboratory staff, rapid response teams, emergency medical teams and extensive community networks. However, to adequately address the compounding nature of modern crises, the various components of the emergency workforce must collaborate cohesively. True resilience depends entirely on transforming this currently fragmented workforce into a highly trained, interconnected and rapidly deployable asset. To achieve this, WHO is actively advancing regional workforce capacities through the Global Health Emergency Corps initiative. This initiative – supported by the Gates Foundation and the Institute of Philanthropy – seeks to build a seamless network of emergency workforce across borders and sectors, ensuring that when a crisis strikes, a standardized, well-coordinated and trained workforce is immediately ready to respond. “Scaling up emergency workforce readiness is no longer optional,” said Dr Gina Samaan, Regional Emergency Director for WHO in the Western Pacific. “It is the definitive factor that will determine how effectively the Asia-Pacific region safeguards health and protects lives in an increasingly unpredictable future.” ____________________For more information, or to arrange media interviews, contact: Ara Johannes, WHO Western Pacific Health Emergencies Division: johannesa@who.int WHO Western Pacific Communications: wprocom@who.int
New £1.5m fund to boost communities and businesses
The grant programme offers support for community, environmental and business-focused projects.
WHO urges targeted action to strengthen emergency workforce capacities for shared health risks across the Asia-Pacific region
Kuala Lumpur, Malaysia, 11 June 2026 – At a time when the world is more interconnected than ever, the World Health Organization (WHO) is disseminating a comprehensive regional analysis of shared health risks across Asia and the Pacific, urging Member States to invest in enhancing workforce capacities regionwide to mitigate these risks and ensure health systems are better prepared to anticipate, tackle and withstand a range of crises and shocks. Over 100 delegates from 49 countries and areas in the Asia-Pacific region reviewed results from the regional risk analysis during the WHO-led Asia Pacific Health Security Action Framework (APSHAF) Stakeholders Meeting in Malaysia. Synthesizing insights from 21 strategic risk assessments and more than 800 multisectoral experts, the regional analysis highlighted an urgent imperative: countries must proactively invest in emergency workforce preparedness to navigate a landscape where climate hazards, disease outbreaks and geophysical events increasingly overlap. These complex converging crises create devastating, compounding impacts on health systems and communities - reiterating the need for investing in a fit-for-purpose regional health workforce and multisectoral action. Key findings: an evolving risk landscape More than half of the participating countries ranked flooding, cyclones, dengue and pandemic-potential respiratory pathogens as being of high or very high risk, while antimicrobial resistance, landslides and gastroenteritis remain widespread concerns as well. “Given that 51% - over half - of these assessed hazards are deeply interconnected, isolated health interventions are no longer sufficient,” said Dr Saia Ma’u Piukala, WHO Regional Director for the Western Pacific. “Extreme weather events like cyclones and floods directly trigger subsequent disease outbreaks, while environmental degradation - driven by sea-level rise, coastal erosion and saltwater intrusion - fuels health risks across the Pacific. Mitigating these cascading risks requires unified, cross-sectoral action linking environmental, agricultural and public health policies to build true regional resilience.” Priority recommendations for action To address critical vulnerabilities, WHO calls on Member States in the Asia-Pacific region to urgently prioritize the following strategic actions: Bridge workforce capacity gaps. Embed and standardize emergency preparedness within academia to promote regional workforce interoperability. Foster multisectoral coordination. Address ad-hoc taskforce responses and fragmented surge support through formalized contingency plans and standard operating procedures that are frequently updated and tested. Secure sustainable financing for emergencies. Overcome systemic barriers to access dedicated funding for both immediate anticipatory actions and long-term emergency preparedness initiatives. Enable emergency-ready primary health care. Embed emergency management into public health workforce readiness planning. Ensure that emergency planning is inclusive. Establish clear pathways for inclusive emergency planning that actively involves communities most at risk and other vulnerable groups. Optimize communication. Update risk communication and community engagement strategies, aligning them with seasonal risk calendars. Elevating workforce readiness to meet regional health risks While the gaps identified are significant, the Asia-Pacific region possesses solid foundational pillars, including dedicated clinicians, laboratory staff, rapid response teams, emergency medical teams and extensive community networks. However, to adequately address the compounding nature of modern crises, the various components of the emergency workforce must collaborate cohesively. True resilience depends entirely on transforming this currently fragmented workforce into a highly trained, interconnected and rapidly deployable asset. To achieve this, WHO is actively advancing regional workforce capacities through the Global Health Emergency Corps initiative. This initiative - supported by the Gates Foundation and Institute of Philanthropy - seeks to build a seamless network of emergency workforce across borders and sectors, ensuring that when a crisis strikes, a standardized, well-coordinated and trained workforce is immediately ready to respond. “Scaling up emergency workforce readiness is no longer optional,” said Dr Gina Samaan, Regional Emergency Director for WHO in the Western Pacific. “It is the definitive factor that will determine how effectively the Asia-Pacific region safeguards health and protects lives in an increasingly unpredictable future.” For more information, or to arrange media interviews, contact: Ara Johannes, WHO Western Pacific Health Emergencies Division: johannesa@who.int WHO Western Pacific Communications: wprocom@who.int
Microsoft continues its big Linux push at Build 2026
Microsoft is releasing a server Linux, a container Linux, and a Windows 11 built for Linux programmers. Here's why.
Towards a responsive health system and equitable access to quality RMNCAH services
Indonesia’s vast geography and sociocultural diversity shape the delivery of reproductive, maternal, newborn, child and adolescent health (RMNCAH) services in ways that are both enabling and challenging. Across provinces, significant variation has been observed in how services are planned, resourced, and delivered. These variations in service standards and quality are felt daily in the lives of women, newborns and adolescents. Despite these challenges, progress is visible. National estimates show a drop in maternal mortality ratio, from 331 to 140 per 100 000 live births since 2000, signaling improvements in care quality and access. Fertility has stabilised and contraceptive use has grown, yet unmet reproductive health needs persist, and adolescent pregnancies continue to reflect early marriage and limited access to youth-friendly services.To better understand how Indonesia’s health system has evolved under decentralisation, the Ministry of Health, supported by World Health Organization (WHO), United Nations Population Fund (UNFPA), the United Nations Children’s Fund (UNICEF), IPAS and the Asian Development Bank (ADB), conducted a joint external review of RMNCAH programmes. This review draws on multiple sources of evidence, including existing literature, policy documents, national health system data, as well as field visits to six selected provinces to represent Indonesia’s geographic and administrative diversity. During the field visits, review teams observed service delivery in health facilities, spoke with health workers and local leaders and met mothers and families to understand how RMNCAH policies are operationalised. One of the challenges identified was the management of low birthweight (LBW) infants, a major contributor to neonatal deaths, under resource constraints. One midwife described a severe case of extremely LBW twins, one stillborn and the other died after three days of care. She recalled how the surviving infant struggled to swallow and may not have received breast milk, while simultaneous emergencies required the team’s attention, affecting the care provided to the infant.A subsequent review of the case by the district health office revealed insufficient antenatal care, fragmented maternal medical history due to population mobility, referral delays, limited provider capacity in neonatal intravenous access and a heavy workload that constrained proper newborn monitoring. These insights informed recommendations to strengthen both system-wide and service-level responses. Since the early 2000s, Indonesia’s decentralisation initiative has given much of the responsibility for funding, staffing and managing health services to regional governments. While the Ministry of Health sets national clinical standards, daily management of public health facilities falls under regional authorities through the Ministry of Internal Affairs. While this arrangement allows services to be tailored to local needs, it also depends heavily on local capacity for planning, budgeting and management. Health facilities and district health offices are better positioned to translate national priorities into local action when they have access to consistent technical support, helping health workers manage resource constraints and infrastructure gaps.The complexity of Indonesia’s health system governance is no easy feat to navigate. Understanding these dynamics is essential to strengthening policy, improving coordination and ensuring more equitable access to services across Indonesia. Under the leadership of Ministry of Health, recommendations from this exercise will be key in guiding the nation’s roadmap to an equitable and quality health system for RMNCAH.Written by Edit Oktavia Manuama, National Professional Officer (Maternal, Newborn, and Child Health), and Jessie Yunus, National Professional Officer (Gender, Rights, Equity, and Disability Inclusion)
31 hours with the spit-shined Mina the Hollower (and 34 with the four games that came before it)
To truly appreciate Mina The Hollower, an extraordinary new throwback of a game, I sent myself to Yacht Club University. That’s not a real institution of higher learning, but it’s the best way I can explain much of the past several weeks as I prepared to play Mina by playing the four biggest game previously made by studio Yacht Club Games. I had expected Mina the Hollower, in development for six years for PC and consoles, to potentially be something special. A demo I tried in March had felt great. Mina the Hollower had an old-school premise: a singular move for its hero that felt so good to control and so rich with possibilities that, in the hands of skilled designers, it could be riffed on in various ways for the length of a full game. Mina’s core maneuver, her hollowing, made her sort of an upside down Super Mario. Nintendo’s hero jumps through the air, discovering power-ups at the apex of his jump by bonking overhead blocks, then defeating enemies by landing on them. Mina essentially jumps into the ground, digging (“hollowing”) into the earth to fetch buried treasure, then burrows for a short distance to emerge on the other side of a wall that hides treasure or an enemy that needs some battering. I wanted to understand how good Yacht Club was at making games. I wanted to see how far they’d come. If Mina was terrific—as I predicted it might be—I wanted to feel how they got there, one button press at a time. On May 6, 21 days before the writing of this review, I checked with Yacht Club Games co-founder and programmer David D’Angelo, to ask which of the studio’s games I should play to truly appreciate the new one’s design. “Hmmm all of them?” he wrote back. “Starting with Shovel Knight definitely is helpful,” he continued, referring to Yacht Club’s first game. He gave me a link to a spreadsheet of over 400 cheat codes that could help me out, if I found the game too tough.1 “Most folks say Specter of Torment is the least difficult and quickest to finish in terms of playtime, and [it] refines much of Shovel Knight,” he told me. “King of Cards is a big celebration of everything we did in [the Shovel Knight compilation] Treasure Trove— might work for you better if you’re a fan of shorter, Mario-style courses. And it’s probably the closest to Mina in terms of polish.” So that was that. Four games, none of which were required. Mina is a whole new game in a whole new world, best I can tell. I’d barely played that first Shovel Knight before and never the other three. I just thought it’d help. It did. It turns out that playing a game studios major works before their latest is very illuminating.
Advancing high-threat pathogen preparedness in WHO South-East Asia Region: 2025 in review
Effective preparedness for high-threat pathogens demands more than technical tools — it requires a coherent strategy, sustained country engagement, and the institutional infrastructure to translate evidence into action. In 2025, the Pandemic and Epidemic Management (PEM) Unit advanced all three, working across the full spectrum of high threat pathogen (HTP) preparedness: from methodology development and evidence generation to country-level technical support, emergency response, and regional workforce strengthening.At the core of the PEM unit's work is building the regional evidence and policy architecture needed to prioritize and respond to HTPs systematically. A major milestone was the development of the HTP Prioritization Methodology — a structured, multi-criteria approach to ranking pathogens by epidemic potential, severity, and national context — and its national pilot in Bangladesh, where SARS-CoV-2, Nipah, dengue, and cholera emerged as the highest-priority threats, informing the PEM unit's contribution to 2026–27 biennium prioritization and workplan development (Access link here).Underpinning this work, the PEM unit advanced the peer-reviewed evidence base for HTP preparedness in the South-East Asia Region (SEAR), with three publications in international journals in 2025: Development of a zoonotic influenza distribution assessment and ranking system (ZIDAR): Technical application in Nepal to support cross-sectoral risk-based surveillance in One Health; Implications for influenza A virus surveillance in Southeast Asian Region countries: a scoping review of approaches for the surveillance of swine influenza viruses at human-swine interfaces in BMJ Public Health; and Operationalizing multisector partnerships: a Theory of Action and Reflection tool for zoonotic influenzas in Health Policy and Planning. Together, these contributions move the Region’s HTP preparedness agenda from practice to science — generating the transferable methodological foundations that will inform evidence-based capacity strengthening in Member States.Country-level engagement in 2025 reflected the breadth of contexts in which HTP preparedness must function. Technical support was provided for Mpox and cholera events across the Region, including coordination of cholera and acute watery diarrhea prevention and control in Myanmar in the wake of the March 2025 earthquake. In Myanmar, the PEM unit contributed technical leadership to the earthquake emergency response — one of the most complex humanitarian emergencies in the SEAR — as Health Operations and Technical Support lead within the Incident Management Support Team. This included strengthening emergency response planning, supporting operational and after-action reviews, and providing monitoring and evaluation support for both acute and protracted crisis response. The breadth of HTP support provided to emergency operations across the SEAR was documented in the PEM unit’s contribution to the regional report for the Health Security Interface Technical Advisory Group.In Sri Lanka, technical collaboration with the WHO Country Office and the Ministry of Health laid the groundwork for the National Steering Committee's 2026 annual meeting, development of Standard Operating Procedures for specialized emergency response, and a national training programme — all structured around evidence-based risk assessment for specialized hazards including HTPs.Across the SEAR, the unit contributed to strengthening the workforce architecture that underpins HTP response. Technical inputs shaped the WHO South-East Asia Regional Health Emergency Workforce Strategy 2025–2030, and the PEM unit supported conceptual development of the health emergency workforce framework for the Pandemic Fund Round 3 proposal.Alongside this, the unit's sustained engagement on the meningitis agenda culminated in the launch of the Regional Implementation Framework to Defeat Meningitis in South-East Asia by 2030 at the Seventy-eighth Session of the Regional Committee, ensuring the Region's priorities were reflected in the Global Technical Task Force and expanding the unit's HTP engagement beyond outbreak-prone zoonotic pathogens (Regional Implementation Framework to Defeat Meningitis in South-East Asia by 2030).Taken together, 2025 demonstrated that meaningful HTP preparedness is built incrementally — through methodology, engagement, and the steady accumulation of institutional capacity across Member States.Bangladesh piloted the HTP Prioritization Methodology and identified the highest-priority pathogens in the country context (Photo credit: WHO Country Office, Bangladesh).
How integrating tradition and self-care has strengthened public health in the Americas
On 13 May 2026, a regional dialogue for the Americas titled, Innovative Experiences to Strengthen Health and Self-Care through Traditional, Complementary, and Integrative Medicine, was hosted by EsSalud, the government agency responsible for social security and health care in Peru.The event brought together representatives from the World Health Organization (WHO), the Pan American Health Organization (PAHO), WHO collaborating centres, the health sector and academia. It presented regional perspectives from BrBolivia, Brazil, Mexico and Peru to explore how self-care and traditional medicine can strengthen public health, empower communities and support more inclusive models of care. Across all four countries, a clear message emerged: traditional medicine is not being positioned as an alternative to formal systems, but as a way to strengthen them. In the Americas region, the challenge is to consolidate intercultural and holistic care, with the aim of strengthening the healthcare system – making care more preventive, culturally relevant and community-based.Peru: institutionalizing complementary care over 28 years Dr Martha Villar López from EsSalud Peru demonstrated how integration can be institutionalized over time. With nearly three decades of investment, including a research programme dating back to 1998, traditional medicine is now embedded within public health infrastructure. EsSalud’s flagship programme, Reforma de Vida, operating as Prevenir, takes multidisciplinary teams into workplaces to reduce and detect risk factors for chronic noncommunicable diseases. Education cycles are structured around three pillars: celestial nourishment, focused on life purpose and movement; terrestrial nourishment, centred on regional food and healthy diets; and human nourishment, addressing identity, relationships, stress and spirituality. Grounded in Andean cosmovision and the principle of the ayllu, the programme aligns with local cultural values. Since 2007, it has trained over 6600 health leaders, certified more than 3100 health-friendly organizations and built alliances with nearly 11 000 employers.Bolivia: legal recognition and medical pluralism Adelino Pau Carpacheco, an 82-year-old Callawaya healer, described working with more than 220 medicinal plants, supported by deep generational knowledge. Traditional healers and plant medicine are highly respected in the country. Bolivia’s contribution also highlighted the role of policy in enabling integration. Through Law 459, traditional medicine has been formally recognized within a legal framework and led the country to medical pluralism where traditional medicine coexists with biomedicine, and both are now offered free of charge through the public health system. Mexico: preserving Indigenous knowledge and reinventing food culture Mexico presented two complementary approaches focused on knowledge preservation and food systems. In Veracruz, communities partnered with a university to safeguard Totonac traditional medicine through a diploma programme launched in 2019. This collaboration has already produced practical outputs, including manuals and a dictionary, helping to sustain knowledge at risk due to migration and generational change. Alongside this, Dr Hernán García, Directorate of Traditional Medicine and Intercultural Development – Mexico, explained how the Dieta de la Milpa programme addresses Mexico’s dual burden of malnutrition and rising noncommunicable diseases. Rooted in traditional Mayan cultivation systems and ingredients, it promotes healthier diets through community-led, intercultural approaches involving local authorities, Indigenous leaders and cooks. By reconnecting food, culture and health, it offers a practical pathway to prevention. Brazil: community therapy as a public health tool Brazil’s experience centred on Integrative Community Therapy, a methodology developed over 40 years ago by Dr Adalberto Barreto and now used in more than 47 countries. Therapy circles create spaces where participants share experiences and coping strategies, building social support networks at very low cost. Within Brazil’s Unified Health System, the approach has expanded rapidly since its inclusion in national policy in 2017. By 2025, more than five million integrative practice procedures were delivered annually in primary care, with registrations for this therapy increasing by over 500% in eight years. The main challenge now is equity, with access still concentrated in urban areas such as São Paulo. A shared regional direction against a global backdrop Drawing these experiences together, Dr Natalia Aldana of the TCIM Network of the Americas highlighted the shared outcomes of the interventions discussed. Such approaches strengthen healthy behaviours, social networks and community resilience; they are low-cost, adaptable and enable active participation in care, while showing potential to reduce the burden of noncommunicable diseases.The regional momentum mirrors a broader global shift. Dr João Paulo Souz, Director of BIREME (Latin American and Caribbean Center on Health Sciences Information), the specialized center of PAHO/WHO, emphasized that the Global Traditional Medicine Strategy 2025–2034 promotes a vision centred on people, evidence and integrated use. He noted that health should be understood through the relationships between people, community, nature and spirituality. Self-care interventions as a critical pathway towards universal health coverage Dr Manjulaa Narasimhan, Unit Head for Sexual Health and Well-being across the Life-course at WHO, delivered a presentation titled Advancing Self-Care in Traditional Medicine: Aligning the WHO Traditional Medicine Strategy 2025–2034 with the WHO Self-Care Framework, co-authored by Dr Geetha Krishnan Gopalakrishna Pillai, Unit Head for Research, Data and Innovation at the WHO Global Traditional Medicine Centre. WHO recommends self-care interventions for every country and economic setting as a critical path to reach universal health coverage – and traditional medicine acts as a bridge for self-care. Dr Narasimhan explained that traditional medicine contributes most effectively to self-care when embedded directly into primary health care, not operating in parallel, siloed systems. This, she stated, “is possibly the only sustainable way to deliver continuity of care that meets the needs, rights and priorities of communities and individuals”. The Global Traditional Medicine Strategy 2025–2034 is a move towards a more people-centred approach to health care that champions holistic approaches to health equity and patient autonomy.The integration of traditional medicine and self-care requires collaboration across disciplines, clear referral pathways, trained health and care workers, and strong leadership that supports integration. The WHO self-care competency framework defines 10 key competencies for health and care workers to support self-care in their clinical practice, supported by the WHO guideline on self-care interventions for health and well-being. These documents help health-care workers safeguard their own well-being and ensure that care is consistent, safe and grounded in shared standards and values.Together, the discussion through this dialogue points to a fundamental shift in how health systems are designed in the region, and globally, towards models that are more inclusive, culturally-grounded and responsive to the needs of the communities they serve. It is a move towards a system where traditional medicine is respected and responsibly integrated, where self-care provides empowerment and evidence-based care, and where health systems are supportive rather than being distant from these systems.Traditional medicine perspectives from Bolivia, Mexico and Peru - WHO's "Restoring Balance" seriesInnovative Experiences to Strengthen Health and Self-Care through Traditional, Complementary, and Integrative Medicine was streamed in Spanish, with Spanish and Portuguese subtitles. Recordings are available through the CABSIN YouTube channel with Portuguese subtitles and on the BVS MTCI Americas YouTube channel with Spanish subtitles. Dr Narasimhan’s session can be watched in English on both channels.
Additions to David Blunkett’s alternative king’s speech
Letters: Readers praise – and point to omissions from – the former home secretary’s proposed programme for government
Mission admission: AI, data science courses surge across Gujarat campuses
Vadodara: Artificial intelligence (AI), data science and emerging technology programmes are witnessing a major push across Gujarat, with universities rapidly introducing specialised courses to tap growing student demand and industry requirements.
‘Never-ending’ AI slop strains corporate hacking reward schemes
‘Bug bounty’ programmes have seen a jump in spurious AI-generated submissions
From leadership to succession, executive courses target wealthy families
Short business school programmes are helping scions prepare, moving into territory dominated by banks and advisers
Chartbook 449: Voldemort on Threadneedle street. The Bank of England and the "haunted house" of English politics.
Imagine the scene: In some Harry Potter version of 21st-century London, a group of deathless UK Treasury officials gathered from across the last century huddle over warm pints and glasses of Chardonnay. Around the table there are officials from the 1920s, the 1930s, the 1970s, 2022 and today. Inevitably, in May 2026, the subject of conversation is the disintegration of the current Labour government. Despite its huge majority in parliament, it has been reduced to tatters by catastrophic local election result. These exposed the fact that rather than having a government with a clear popular majority, the UK is like most other modern societies divided into 5 segments each of which commands between 26 and 16 percent of the vote. Perhaps unsurprisingly, the leadership at Nos 10 and 11 Downing Street - where the Prime Minister and the Chancellor (Treasury Secretary) work - seem paralyzed. They are caught between mounting discontent over unfairness and the cost of living, and tough fiscal strictures that push them into making unpopular spending decisions. In the London pub, the Treasury officials from across the ages, can barely hide their satisfaction at the latest display of democratic politics caught in the vice-grip of financial logic. “Remember the mur d’argent and the banker’s ramp?” “Just like yesterday!” There are smirks around the table. Then the representative of 2026 pipes up: “One thing you have to say about the current lot (referring to the latest hapless Labour government), you don’t have to teach them about the bond market!” There is a murmur of ascent from the Treasury Mandarins. The trauma of the fiscal crisis of September-October 2022 sits deep. Back then, in the final stages of Tory decay, a ‘mini budget’ that challenged fiscal orthodoxy led to a brief but fierce panic in one of the oldest government bond markets in the world (aka gilt market). Now all you have to do is to mention the “bond market” to hush debate. [ Paul Mason@paulmasonnews In the name of public service, and as ex-economics editor of BBC Newsnight, I offer to do a zoom call, tonight, with any Labour MP who wants to understand why bond markets do not "fall into line" with governments. 1/ 3:57 PM · May 12, 2026 · 466K Views 224 Replies · 674 Reposts · 3.93K Likes ](https://x.com/paulmasonnews/status/2054229532404519082?s=20) “And the funny thing is”, the young man in the huddle continues, “they don’t even want to talk about … ”. There is a sudden hush. Significant looks are exchanged around the table. About? One of the senior figures puts down his glass with a decisive “clink”. He-Who-Must-Not-Be-Named has entered their thoughts. Meanwhile, a few miles away in a grubby pub in Bloomsbury, two conspirators from the camp of Critical Macrofinance huddle over cans of low-alcohol IPA. They look at each other and blurt out loud: “The Bank!” “Everyone in the bloody Labour party is talking about the bond market. But why aren’t they even mentioning … the Bank of England!?” “Why is no one talking about Voldemort?” In Paul Mason’s blogpost, after much chest-thumping about basic fiscal logic, the basic point about the Bank of England is buried in the fine print at #3 in his list of suggestions as to what a radical Labour government might actually be able to do! [ Conflict & Democracy Down with the bond market! Down with gravity! It may seem unfair to focus on Labour MP Paula Barker for her off-the-cuff assertion that the bond market would have to “fall in line” with Andy Burnham, should he replace Keir Starmer as prime minister. But Burnham himself told the New Statesman that Labour had to “get beyond this thing of being in hock to the bond markets… Read more 2 days ago · 100 likes · 3 comments · Paul Mason ](https://htsf.substack.com/p/down-with-the-bond-market-down-with?utm_source=substack&utm_campaign=post_embed&utm_medium=web) Back in Bloomsbury they shake their heads and ask: “Didn’t we learn anything from the Eurozone crisis?” Meanwhile, as if summoned to the conversation by some higher force, the “pink pages” announce: “The days of ultra-cheap government borrowing have come to an end” and Martin “Whizzard” Wolf publishes the graph of the season Look at the UK in 2026, perilously positioned on the upper edge of the pack. No wonder no one in London needs any lessons about the “bond market”. But, look again. Imagine how they feel in Rome. What is London’s nightmare in 2026? The nightmare is that you end up like Italy in the early 2010s during the Eurozone crisis. Once comfortably situated in the middle of the pack, watching with horror as your ten-year yields explode to 7 percent and “spreads” become a national nightmare. One of the largest economies in Europe, a founding member of the euro, stigmatized. But the message of the Italian experience is ambiguous. After all, the stigma didn’t last. In 2026, Italy borrows at rates lower not only than the UK but the US. The US, which, as everyone knows, enjoys the “exorbitant privilege” of being the issuer of reserve, safe asets. What kind of magic is this? How did Italy, in the space of fifteen years, go from being good, to bad and back again? Which brings us back to our dissident friends in their Bloombury boozer and their memories of the Eurozone crisis. Italy never was Britain - with its ongoing fiscal deficits. Without interest payments, on primary balance, from 2000 to 2020 Italy ran a tight fiscal ship. Even in 2008 it barely went into deficit and when it was being put on the rack in the early 20210s its primary surplus matched that of austere Germany. So, what happened? How did it end up stigmatized? Of course Italian politics didn’t help. Berlusconi was at the helm and he had legal issues. But amongst friends in the Bloomsbury pub, Berlusconi is a sideshow, the name we whisper to each other is “Trichet”. From 2004 to 2011 the ECB was headed by Jean-Claude Trichet, ex of the French Treasury, more German than the Germans. After 2009 as the news of the Greek fiscal disaster broke, the European bond markets wento into panic mode and Trichet began a brutal game of cat and mouse. Between 2009 and 2011, Trichet intervened in the bond market to help, only when he thought he had compliance with austerity. When he thought they were uncooperative, he withdrew. In the summer of 2011, he even made direct suggestions to his Italian counterparts in Rome, as to how Italy should be governed. It was this cat and mouse game that drove the bond markets crazy and exposed Italy to a violent squeeze. When Mario Draghi took over the ECB at the end of 2011 and declared “whatever it takes”, the pressure on Italy, gradually eased. It is that starring role that has made Draghi into the towering figure in European politics that he remains today. So now you see why voices in London hush when it comes to the Bank of England. “The bond market” isn’t an irresistible objective force like the weather or an avalanche. It can appear like that. But that depends on the way it is being handled, or not handled by the central bank. Which is why the silence about the Bank of England in London right now is so significant. If you think this all sounds a bit fishy, coming from a left-liberal Keynesian like myself, well, let me introduce you to Robin Brooks, who, to put it mildly, plays on a different quidditch team to me. Here, from the position of a fiscal hawk is Robin’s celebratory account of the Bank of England’s role since 2022; In October 2022, at the height of the bond market blow-up in the UK, something incredible happened. Governor Andrew Bailey told British pension funds the Bank of England would end its support program for the country’s fragile gilt market, drawing a line under how much help the central bank was willing to give to exposed pension funds and - implicitly - the government. By the end of that week, Kwasi Kwarteng - the finance minister - had resigned. Prime Minister Liz Truss would soon follow. This episode is so incredible because it contrasts with what happened in the Euro zone earlier that year. Bond markets in Spain and Italy were under pressure amid high inflation and rising interest rates. In the middle of this, Mario Draghi - Italy’s Prime Minister - resigned, compounding pressure on bond markets of high-debt countries on the Euro periphery. Unlike the Bank of England, the ECB caved. It bought Italian and Spanish government bonds in an effort to cap yields and introduced a new tool that signaled to markets it might do such caps more frequently going forward. Faced with pressure on bond markets, the ECB capitulated to political pressure from high-debt countries like Italy and Spain. The Bank of England stood its ground and toppled the Truss government. This kind of thing has long-lasting consequences. It means markets price a higher probability of yield caps in the Euro zone, which keeps Italian and Spanish yields artificially low, while markets feel free to push up UK yields without fear of central bank intervention. As I flagged in yesterday’s post, this means you really can’t compare UK yields to those of other high-debt countries. The UK looks worse, but only because its central bank isn’t interfering with markets. There’s more to this than just that 2022 episode. The Bank of England has also been much more aggressive in its quantitative tightening (QT) than other central banks. If one motivation for quantitative easing (QE) is to lower bond yields - especially longer-dated ones - then it stands to reason QT pushes yields up. The left chart above shows a four-quarter moving average of UK government debt issuance (black line) in percent of GDP and which sectors absorb this issuance, including the Bank of England (blue bars). The right chart above compares the Bank of England’s accumulation or run-off of government bonds (blue line) with that of other central banks, where this blue line is the same as the blue bars in the left chart. The Bank of England was quicker and more aggressive than other central banks in downsizing its bond holdings, so UK yields will have risen more than elsewhere also for this reason, not just because of Governor Andrew Bailey’s remarks in October 2022. Back in October 2025, after a conversation in New York with friends in British politics, my sense of dysphoria was such that I raised the issue of the Bank of England openly in the FT Since 2008, the UK has slid into a deep economic and political predicament. Growth has stagnated to a degree far worse even than in the 1970s. The Tory leadership’s wager on the Brexit referendum spectacularly backfired, leaving the UK isolated from Europe and at the mercy of its special relationship with the US, many of whose political class regard the UK as a basket case. After years of austerity, the Labour party lurched to the left and then back to the centre. The Tory party has been eclipsed by the populist nationalism of Reform. Any British government should be worrying first and foremost about how to restart growth. Instead, Keir Starmer is beset by shades of the gilt market panic triggered by the Liz Truss government in 2022. The debt level is higher than in recent years, but there is no cause for panic. UK debt is at far from critical levels and of long duration. Whether you want to “take back control” or launch progressive economic policy, a democracy dogged by fear of bond market vigilantes is unhealthy. In a country that is a monetary sovereign, this climate points to one thing: a disconnect between the government and the central bank. Since 1997, the independence of the Bank of England has become a sacred cow. But independence is what you make of it. And in the wake of the gilt market crisis of September 2022, relations between the Bank of England and the UK government need a reset. In normal times, there is no doubt that an inflation-targeting independent central bank can serve a country well. But since 2008, the UK and other advanced economies have not had the luxury of such simple problems. To their credit, central bankers around the world have not stood on orthodoxy. After 2008, the US Federal Reserve rescued the global banking system and, through quantitative easing, it stabilised the Treasury market in the face of huge deficits. In Europe, things were trickier. Both the Bank of England under Mervyn King and Jean-Claude Trichet’s European Central Bank played cat and mouse with national governments. This was a high stakes wager that between 2010 and 2012 escalated bond market tension and triggered a disastrous turn to austerity. Shaken by the impact of those shocks, their successors, Mark Carney and Mario Draghi adopted a more protective stance (assuming you were not the government of Greece). Recall that Draghi’s legendary slogan, “Whatever it takes”, was uttered to face down the City of London’s bond vigilantes. In 2015, Draghi launched QE — financial repression by another name. In 2016, Carney used the authority of the Bank of England to stabilise markets following the vote for Brexit, an exemplary demonstration of how central banks can underpin democratic choice, even when those choices are wrong headed. All these were independent central bankers steeped in the best practice of the 1990s, who recognised that historic crises demanded radical action. It was the price surge of 2021-2023 that poisoned the atmosphere. Though the shock came mainly from the supply side, central banks ended up in the dock. Nowhere more so than in the UK. The Bank of England reacted with aggressive normalisation. Faced with a cost of living crisis, the governor called for workers to accept real wage cuts. In early 2022, as gas prices were at record levels and Russia’s army was poised to invade Ukraine, the Bank adopted a stringent programme of quantitative tightening, elevating interest rates. When the Truss government got itself in trouble, the Bank took almost a week to come to the rescue. Rather than enacting a charade of normality, it is time to recognise that in 2025 the UK faces a period of historic transition. To meet this challenge, what is needed is a new concordat with the Bank. This should not ignore inflationary pressures or the long-run trajectory of debt, but should affirm the priority of reviving investment-led growth. One could follow Donald Trump in demanding interest rate cuts. The Bank could shadow the ECB in its commitment to capping Eurozone yields. But the top priority should be to lay the ghost of September 2022. The Bank’s slowing of QT last month was a concession. An immediate and complete end would send the right signal. Such a concordat will not by itself restore sanity to politics, solve the housing problem or rebuild the NHS. But it would help to lift the fear of bond market crisis, which is paralysing the effort by democratic politicians to answer the fundamental questions facing the nation. Now, that call for a new concordat between government and Bank of Englands seems more urgent than ever. The problem is that in October 2025, Starmer still had some authority. Today the government is in tatters. And when you are the “under the harrow” - to echo a phrase of Montagu Norman’s from the 1920s - it is the worst possible time to consider institutional change. To make general arguments at a time of crisis can only seem like special pleading rather than a general argument for long-term change. The same, unfortunately, is also true for the other basic institutional reform that Britain urgently needs i.e. the abolition of the out-dated first past the post electoral system and its replacement by a moderated form of proportional representation. And thirdly - whilst we are saying the quiet parts out loud - Britain needs to reopen the question of EU membership. What the local election results of 2026 show is that this remains a key issue. And what they also show is that there is a clear majority that would favor a return. Until these basic features of Britain’s political economy are addressed the country will carry on its politics as though in a haunted house, governed by governments that lack actual majorities, conjuring up false constraints whilst ignoring the real ones. This one is for DG and MI. I love writing the newsletter. If you enjoy it too and fancy buying me a coffee once a month, you know what to do. Click below! Subscribe
Scientists discover vitamin B2 may help cancer cells survive
Scientists have uncovered a surprising dark side to vitamin B2: it may help cancer cells stay alive. The vitamin supports a cellular shield that protects tumors from ferroptosis, a form of programmed cell death linked to cancer suppression. In lab tests, researchers used a vitamin B2-like compound called roseoflavin to break down that protection and trigger cancer cell death.
Protecting lives everywhere
In 2025, the WHO Health Emergencies Programme responded to a growing number of health emergencies driven by conflict, climate shocks and disease outbreaks, amid severe funding constraints. This report shows how WHO delivered life‑saving health services, supported countries to detect and control outbreaks, and helped maintain essential health care in some of the world’s most fragile settings
Universal and UCF launch new themed entertainment school
Universal is investing $10 million in the new UCF programme
'The Sports Advisors' Podcast Debuts with LIV Golf Deep Dive
Actionable intelligence from senior operators who have built, bought, sold, programmed, monetized, and scaled sports businesses.
Liberia’s community health assistants are up at dawn to work at the healthcare frontline
Launched after the Ebola epidemic of 2014–2016, the community health assistant programme has proven itself valuable. Is it now at risk?
Radiological protection and public health experts discuss emerging challenges and future priorities
The 84th meeting of the NEA Committee on Radiological Protection and Public Health (CRPPH) included topical sessions, discussed the 2027-2028 programme of work and marked a chair transition, with the appointment of Antony Bexon (United Kingdom) as the new Committee Chair, succeeding Thierry Schneide...
‘The reality, for better or worse’: Columbia comp sci students and faculty grapple with AI’s disruption of the field
‘The reality, for better or worse’: Columbia comp sci students and faculty grapple with AI’s disruption of the field ‘The reality, for better or worse’: Columbia comp sci students and faculty grapple with AI’s disruption of the field A field that once seemed like a direct path to stable, lucrative work is becoming less certain under AI, students and faculty told Spectator. By Ria Vasishtha and Arjun Menon May 3, 2026 Shanying Liu / Deputy Illustrations Editor Asia Genawi, SEAS ’29, first encountered artificial intelligence during her sophomore year at her high school in Indiana. Back in 2023, policies on AI varied widely—even within the same district—and some schools had no guidance at all. As Genawi began to see the effects of AI trickle into her classroom, she turned to guidance from her home state’s Department of Education, which she said she found “outdated and inaccessible.” Genawi spent the rest of her high school career dedicated to the issue, including writing a 15-page memo exploring varying AI policies across Indiana schools, which she sent to every Indiana state senator and representative whose contact information she was able to find. She later helped draft a bill that would have required public high schools to establish and share their own AI policies with students in an accessible format. But with so many other bills already awaiting referral, hers never made it to committee. When Genawi arrived at Columbia to study computer science, she found that the gaps she had spent years trying to address in Indiana had followed her there. Many students and professors were also grappling with what AI meant for the field. Across Columbia’s undergraduate schools, computer science has become the most popular major—accounting for around 11 percent of degrees awarded in Columbia College, 32 percent in the School of Engineering and Applied Science, and 12 percent in the School of General Studies in 2024. While the number of computer science majors in SEAS grew from 166 to 173 during the 2024-25 academic year, the total number across the three schools fell around 4.5 percent from 393 to 375, driven by declines at Columbia College and General Studies. At Barnard, it has grown to become the second most popular major as of 2025, up from third the year prior. The number of degrees awarded have grown fivefold since 2016. Faculty members and students in the department told Spectator that the surge in the major’s popularity has been driven in large part by its apparent promise of a secure, well-paid career path. However, they noted that the recent rise of generative AI has compromised the sense of stability that once defined the field, even as interest in technical skills among students persists. According to data from the Federal Reserve Bank of New York in 2024, out of 74 majors tracked, computer science had the fifth highest unemployment rate among majors at 7 percent, while computer engineering had the second highest at 7.8 percent. “Anecdotally, people are moving away from CS as a major,” Daniel Bauer, a senior lecturer in the computer science department, said. “They’re still taking some of our classes, right, because they think they need that, but they’re instead majoring in other things.” Bauer described a field that had shifted from what he called a “nerdy outlier discipline” to one that “everyone needs,” a sign that technical skills have become a baseline expectation across industries with the emergence of AI. “A lot of people thought, ‘Oh, it’s a guaranteed path to a stable income. You get a six-figure job right out of your undergrad,’” Bauer said. Now, companies may see AI as a way to reduce demand for entry-level programmers, especially in what he calls “code monkey jobs,” roles where a large number of employees are “just writing out code nine-to-five.” Chris Murphy, a senior lecturer in the computer science department, described the current moment as the convergence of two forces: the downturn of the job market and generative AI coming onto the scene. “Things kind of started to really pick up in 2014, 16,” he said, recalling the years after the weaker 2010 market. Murphy added that this was also a period where “students were getting more experience outside of class than they were inside of class” through internships, jobs, and side projects. Murphy suggested that the earlier momentum helped make computer science feel like both an academic program and a reliable pathway into work. That feeling is harder to sustain now as the industry reconfigures, which is a shift that students are seeing firsthand. Rebecca Yu, SEAS ’27, said that during a recent internship in Big Tech, she saw that “every single tech company was racing to integrate” large language models. She added that her manager said her intern class was the first to complete their assigned projects, which she attributed to the increased efficiency that comes with AI. Frank Liu, SEAS ’29, said that with AI lowering the barrier to coding, companies now expect everyone to write code. “A lot of companies outright say if you’re not using coding in your job, you might get fired for not being productive enough,” Liu said. Yu similarly expressed that students increasingly have to accept AI being a part of industry workflow, adding that many also “make use of it to maximize their productivity.” Richard Li, CC ’28, described a “franticness” among his peers as the pace of change accelerates. He explained how “some new tool” is released regularly, noting that tools rise and fall in prominence within weeks. He has come to believe that he doesn’t need to “match that speed all the time” and keep up with every development. Li has learned that AI tools allow him to “take a breath” and “get back into the loop much easier than before” when he needs to. While some companies specifically target Columbia when hiring, sending representatives to campus career fairs and recruiting large numbers from Columbia, a computer science degree cannot be treated as a static credential, Yu described. “You can’t just get your degree and stop learning after that. You have to always be learning,” Yu said. “That is something you basically have to expect for your job.” AI has not only affected students’ decisions to major in computer science, but also reshaped how the subject is taught. Across departments, faculty members no longer treat work done outside the classroom as a reliable measure of understanding, shifting instead toward in-person exams, quizzes, and attendance checks. While homework once made up as much as 60 to 70 percent of a student’s grade in computer science classes, Murphy said that breakdown has since flipped, with exams and quizzes now accounting for the majority. “The assumption—especially among pessimists—is that they’re using it to do their homework,” Murphy said. “They take the homework assignment. They put it into generative AI. Out comes the solution. Submit solution. The end.” Murphy said that faculty members ranged in their responses from fully prohibiting AI use to actively teaching students how to effectively work with AI. He said he shifted his approach this year after his teaching assistants called his belief that students weren’t using the technology “naïve,” and now permits students to use AI on assignments. His surveys of students in his introductory classes have told a more complicated story than the one so-called pessimists offer: Around 60 to 70 percent of students who reported using AI said they used it to have concepts explained to them, to clarify assignment instructions, to generate test cases, or to create practice questions. “Those are all ways that you might have had a tutor in the past to do that, and now you have this AI essentially as your tutor,” he said. Bauer has taken a different approach, teaching students how to use AI productively without sacrificing the core principles of the discipline. “People who are trained to actually use AI tools productively, while being in charge of designing the overall project, will be very much in demand in the next couple of years,” he said. Over the past year, a working group of computer science faculty has been redesigning the introductory and intermediate programming sequence to integrate generative AI as both a subject and a tool, representatives from SEAS wrote in a statement to Spectator. The effort is “coordinated” across the department, “not course-by-course,” with a systematic assessment of how AI integration is affecting student outcomes underway to shape the next round of changes. The goal, the department explained, is for students to be able to “read, verify, and reason about code, whether they or a model wrote it.” Tony Dear, senior lecturer in the computer science department, is piloting individualized AI feedback in a discrete mathematics course, while a machine learning course is also testing a Socratic AI dialogue system designed to “guide inquiry rather than supply answers,” the statement reads. Beyond individual courses, SEAS funded seven cross-departmental faculty projects in generative AI this past academic year, spanning biomedical engineering, chemical engineering, industrial engineering, and computer science, according to the statement. This phenomenon extends beyond the computer science department. SEAS’ new AI minor, which it announced in November 2025, reflects the University’s attempt to adapt. The minor is specifically designed for noncomputer science majors and aims to provide “essential AI knowledge” while emphasizing practical and responsible use across disciplines, according to the SEAS website. At the center of the minor is AI in Context, a course taught by a team of faculty from the departments of computer science, applied mathematics, philosophy, music, literature, and the Writing Center, the representatives told Spectator. Bauer described it as targeted at students who want to bring AI into fields like economics or biology, rather than as a path into software engineering itself. At the graduate level, SEAS announced a new Master of Science in artificial intelligence in February, with the inaugural cohort starting in the fall. While recognizing how AI has helped them navigate coursework, students also described its rise as isolating, even among members of the Application Development Initiative, one of Columbia’s largest computer science clubs. “As people start to ask AI for questions that they would normally ask students and members, it starts to isolate people” Li said. Alexa Kafka, BC ’27, echoed Li’s sentiment, pointing out that computer science has always been a collaborative discipline with code reviews and pull requests, even as AI makes independent work easier. Despite this, Kafka noted that she hasn’t been to office hours “in at least a year.” Bauer added that faculty are exploring long-term solutions to the assessment problem. “One of the things that we’re trying to do at the department or school level is to maybe move towards computerized testing facilities,” Bauer said, referring to ideas in the department to revitalize computer labs as an alternative to pen-and-paper exams. “We have to accept that this is the reality, for better or worse.” But more exams, students say, does not mean better learning, nor does it reflect how computer science is actually done. “Code is so variable and can be approached in so many directions, there’s never just going to be one correct answer. There can be multiple optimal solutions,” Kafka said. Students also expressed concern that the shift toward exam-heavy grading pulls focus away from the applied, project-based work that better reflects both discipline and industry expectations. ADI has tried to respond more quickly than the curriculum can. Through a vibe coding workshop this past semester, club members said they wanted to help students understand not just that AI exists, but how to use it deliberately. “Vibe coding” refers to the practice of prompting AI to write code for a task or project, and has become widespread enough that ADI felt the gap in formal instruction was worth addressing, according to Sophia Huang, BC ’29. The workshop introduced students to the concept of context engineering, which Shaina Sahu, SEAS ’27, described as not just writing a prompt, but optimizing “the rest of the relevant information that you would feed into the model.” Without that, students said that AI-generated code can fail at scale or introduce difficult-to-detect bugs. Genawi said the shift toward AI has changed what it means to be good at computer science. “I think the shift has kind of gone towards what can you create and what can you do, instead of, what do you know,” she said. Indeed, during ADI DevFest, its annual hackathon, Li said more teams are trying to complete their projects than in years past. While sign-ups have historically outpaced submissions, Li said this is beginning to change because teams “have a tool that completes the vision for them.” While many students see AI as an equalizer that lowers the barrier to entry for coding and technical work, Murphy said it also creates new equity concerns inside the classroom around who can afford stronger tools and who already knows how to use them. “The equity issues I worry about are students who have access to paid versions of things versus free versions of things,” he said. Although popular AI models like ChatGPT and Claude have free versions available, both have paid models that can reach over $100 per month, which output different qualities of code. Murphy also pointed to differences in prior exposure to AI literacy itself. “Students who go to high schools or K-12 education, where they’re taught AI literacy, prompt engineering, context engineering, they understand how to do this, as opposed to students who go to schools who don’t teach that,” he said. “Then they come in, and then they’re somehow expected to know how to use these tools.” For Genawi, those disparities begin long before students arrive on campus. “It’s very interesting to consider how lucky you were geographically,” she said. “To be born where you were is influencing your ability to get access to these spaces.” Students like Yu, though broadly apprehensive about the future of computer science, are not without hope. “I’m optimistic, because I think if you’re truly passionate about CS, there will definitely be a place in the field to do something you want to do,” she said. Senior Staff Writer Ria Vasishtha can be contacted at ria.vasishtha@columbiaspectator.com. Follow Spectator on X @ColumbiaSpec. Staff Writer Arjun Menon can be contacted at arjun.menon@columbiaspectator.com. Follow Spectator on X @ColumbiaSpec. Want to keep up with breaking news? Subscribe to our email newsletter and like Spectator on Facebook. Produced with Spectate by Emily Ta
Australia becomes the 30th country to eliminate trachoma as a public health problem
The World Health Organization (WHO) has validated Australia for eliminating trachoma as a public health problem, marking a significant milestone in the health of indigenous peoples and in global efforts to combat neglected tropical diseases (NTDs). Trachoma, the world’s leading infectious cause of blindness, no longer represents a public health problem in the country.Australia is among a growing number of countries that have successfully eliminated trachoma, contributing to global progress towards the targets set out in the WHO road map for NTDs 2021–2030.Trachoma is caused by the bacterium Chlamydia trachomatis and spreads through close contact with infected individuals, contaminated surfaces, and flies that carry eye and nose discharge. Repeated infections can lead to scarring of the eyelids, turning eyelashes inward, and ultimately causing blindness if untreated.“WHO congratulates Australia on this important achievement,” said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. “This success reflects sustained commitment, strong partnerships, and a focus on reaching populations most affected by health inequities. It brings us closer to a world free from the suffering caused by trachoma.”Australia’s journey to eliminationAustralia’s achievement reflects decades of targeted public health action, particularly in remote Aboriginal and Torres Strait Islander communities, where trachoma persisted despite its earlier disappearance from the rest of the country.National efforts intensified with the establishment of the National Trachoma Management Programme in 2006, which implemented the WHO-recommended SAFE strategy: surgery for trichiasis, antibiotics to treat infection, promotion of facial cleanliness, and environmental improvement. Regular screening of all communities classified as at-risk of trachoma by teams of qualified health workers formed an important part of the Programme. Interventions were delivered through coordinated partnerships between federal and state governments, Aboriginal community-controlled health services, and local communities.Over time, sustained screening, treatment, and prevention activities, including improvements in housing, water, sanitation and hygiene, led to a steady decline in trachoma prevalence. Australia’s approach included adaptations to reflect its context, such as targeted treatment based on community-level data rather than mass drug administration, and strong integration with environmental health programmes.“Elimination of trachoma is a win for the eye health of communities across Australia, particularly those whose lives have been impacted by a disease that is entirely preventable,” said Mark Butler, Minister for Health and Ageing, Australia. “This major milestone is thanks to Aboriginal and Torres Strait Islander leadership, community commitment and sustained investment over many decades.“The lessons from this work will inform how we approach other preventable health conditions in remote and regional Australia. Aboriginal Community Controlled Health Organisations and local health workers have been central to this success, delivering culturally safe care and community-led solutions.”“This recognition from the World Health Organization reflects decades of work led by Aboriginal Community Controlled Health Organisations, alongside local health workers in remote First Nations communities,” said Malarndirri McCarthy, Minister for Indigenous Australians. “Their work has been critical to eliminating trachoma as a public health problem in Australia.”Advancing global efforts against neglected tropical diseases (NTDs)Trachoma is one of 21 diseases and disease groups that are regarded by WHO as NTDs. Together, NTDs affect more than 1 billion people worldwide, primarily in underserved populations with limited access to essential services such as clean water, sanitation, and health care.Australia’s elimination of trachoma as a public health problem highlights the importance of sustained political commitment and cross-sectoral collaboration in addressing the underlying determinants of health. It also underscores the feasibility of eliminating trachoma even in geographically challenging settings.In addition to trachoma, Australia has several endemic NTDs, including Buruli ulcer, leprosy and scabies. Validation of elimination of trachoma as a public health problem marks the first time that WHO has confirmed the elimination of an NTD in Australia, which becomes the 63rd country globally and 16th in the Western Pacific Region to have eliminated at least one NTD.“Tackling neglected tropical diseases in the Western Pacific Region has long been a challenge for countries across the socioeconomic spectrum, given the complexities in reaching the most vulnerable communities, including in remote areas,” said Dr Saia Ma’u Piukala, WHO Regional Director for the Western Pacific. “As a doctor from Tonga, I’ve experienced these challenges for myself. But I also know that with strategic commitment underpinned by optimal resources and partnerships in health, success is possible as other countries in our region have also demonstrated. I commend Australia on eliminating trachoma as a public health problem and urge all involved to remain vigilant to ensure this status is maintained.”WHO continues to support countries working to eliminate trachoma and other NTDs, ensuring that progress reaches those most in need and that gains are sustained through strong surveillance, appropriately integrated into national health systems, and mainstreamed within the wider health sector and beyond.Editor’s notesNeglected tropical diseases and trachoma elimination effortsNeglected tropical diseases are associated with devastating health, social and economic consequences. Their burden is mainly felt among impoverished communities in tropical areas.Public health targets for the control, elimination and eradication of these conditions were set in the road map for neglected tropical diseases 2021–2030 (https://www.who.int/publications/i/item/9789240010352).In 1996, WHO launched the WHO Alliance for the Global Elimination of Trachoma by 2020 (GET2020), creating a network of governments, non-governmental organizations and academic institutions dedicated to the fight against trachoma. WHO continues to support endemic countries to accelerate progress towards the global target of eliminating trachoma as a public health problem worldwide; 2030 is the new target date.Elimination of trachoma as a public health problem is defined as: (i) a prevalence of trachomatous trichiasis (TT) “unknown to the health system” of < 0.2% in ≥15-year-olds; and (ii) a prevalence of trachomatous inflammation—follicular (TF) in children aged 1–9 years of < 5%, in each formerly endemic district, plus (iii) the existence of a system to identify and manage incident cases of TT.Other countries validated by WHO as having eliminated trachoma as a public health problem are: Algeria, Benin, Burundi, Cambodia, China, Egypt, Fiji, Gambia, Ghana, India, Iraq, Islamic Republic of Iran, Lao People’s Democratic Republic, Libya, Malawi, Mali, Mauritania, Mexico, Morocco, Myanmar, Nepal, Oman, Pakistan, Papua New Guinea, Saudi Arabia, Senegal, Togo, Vanuatu and Viet Nam.
White House Correspondents' Dinner attack suspect is tutor and computer programmer from California
Social media posts that appear to match the California man arrested Saturday in the shooting at the White House correspondents’ dinner show he is a highly educated tutor and amateur video game developer.
Drama between software engineer and Google heats up
Computer programmer and ex-Googler Steve Yegge said he had heard AI use within the the company varies widely, sparking a firestorm of public pushback.
Drama between software engineer and Google heats up
Computer programmer and ex-Googler Steve Yegge said he had heard AI use within the the company varies widely, sparking a firestorm of public pushback.
Indonesia advances One Health and pandemic preparedness through CARE-I
CARE-I is financed by the Pandemic Fund, a global financing mechanism established in 2022 to strengthen pandemic prevention, preparedness and response, particularly in low- and middle-income countries. The programme focuses on advancing the One Health approach by strengthening collaboration across human, animal and environmental health sectors at both national and subnational levels. It will be implemented for three years from 2026 to 2028.
Advancing epidemic and pandemic preparedness through research readiness: SEAR Unity Studies Network Sites chart the way forward in 2026
On 25 March 2026, WHO Regional Office for the South‑East Asia Region (SEARO) convened the first meeting of the SEAR Chapter of the Unity Studies Network Meeting in 2026 to take stock of progress and plan next steps for strengthening epidemic and pandemic preparedness across the Region. The meeting focused on reviewing the ongoing adaptation of selected, standard Unity Study methodologies, sharing field implementation experiences from 2025, and identifying key priorities to guide collaborative work in 2026.Held virtually, the meeting brought together representatives from six Unity Studies network sites across five countries (Bangladesh, India, Nepal, Sri Lanka, and Thailand) as well as participants from all three levels of WHO.The meeting took place against the backdrop of ongoing regional efforts in South‑East Asia to strengthen early investigations and studies for epidemic and pandemic preparedness, with a focus on pandemic influenza and other emerging respiratory pathogens with epidemic and pandemic potential. In this context, and as part of preparedness for the rapid generation of evidence, the WHO Health Emergencies Programme in SEAR (WHE/SEAR) encourages Unity Studies sites to adapt prioritized, standardized Unity Study protocols to their national contexts. This approach supports the generation of timely and reliable evidence to inform public health decision‑making during epidemics and pandemics.These efforts are supported through a combination of experience sharing, participation in the global Unity Studies network webinars, capacity‑building of the national public health workforce, and regional collaboration that promotes inter‑country, inter‑agency, and inter‑ministerial action. In parallel, sites are encouraged to explore diversified funding sources to help sustain research preparedness over the long term.Discussions highlighted the importance of WHO’s catalytic financial support through the Pandemic Influenza Preparedness (PIP) Partnership Contributions (PIP‑PC). When combined with national and institutional resources, this support enables countries and sites to maintain continuity of activities at a core level and remain prepared to respond rapidly and effectively to future epidemics and pandemics.Regional and Global Updates: Opening the session, Dr Pushpa Ranjan Wijesinghe, Programme Area Manager, Pandemic and Epidemic Management (PEM) Unit, WHO Health Emergencies Programme, highlighted the progress made in operationalizing the Unity Studies Network across the Region and acknowledged the collaborative efforts of WHO at all three levels, together with country unity studies sites. He emphasized the availability of limited but catalytic funding through the Pandemic Influenza Preparedness (PIP) Partnership Contribution (PIP‑PC) workplan at SEARO to sustain network activities in 2026, while encouraging sites to leverage additional funding sources to expand implementation.Representing SEARO, Dr Ashok Basnet, consultant, Pandemic Influenza Preparedness reported that, at the regional level, the Unity Studies Network currently includes six sites across five countries: Bangladesh, India, Nepal, Sri Lanka, and Thailand. He noted that in 2025, catalytic funding supported protocol adaptation, training, and pilot implementation. In addition, a regional Unity Studies symposium held during the Global Public Health Summit in Sri Lanka strengthened and advocated collaboration between the Unity Studies site, national decision‑making forum, relevant technical units of the ministry of health, WHO and other partners.The symposium also highlighted the role of early investigations and studies as a key component of a multi‑source surveillance system needed at country level to generate a broad range of evidence. It underscored the critical role of country Unity Studies sites and similar research entities in generating evidence to support public health decision‑making during epidemics and pandemics.Participants of the WHO GISRS Unity Studies Sites Network- SEAR Chapter Meeting 2026 (Photo credit- PEM/WHE/SEARO). SEARO also updated participants on ongoing efforts to develop a regional Unity Studies webpage and to promote participation in global knowledge‑sharing platforms, including webinars and the WHO Community of Practice. Priorities for 2026 include supporting the implementation of Unity protocols, strengthening collaboration and experience sharing across sites, documenting and publishing findings, integrating Unity Studies activities as a component of multi-source national surveillance systems, and building workforce capacity.Dr Nickle Boddington of the Global Influenza Programme (GIP) at WHO Headquarters, which coordinates the Unity Studies Network globally, provided updates on global Unity Studies activities, noting that the network has expanded to 16 sites worldwide. New and updated protocols, including rapid clinical severity assessment tools and standardized data platforms, are being developed to support implementation. The global Community of Practice has also been launched to facilitate technical exchange, and continued support will be provided to sites for protocol adaptation, ethical approvals, and readiness for early investigation during outbreaks. Updates from Unity Studies sites in SEAR in 2025Unity Studies sites shared progress and experiences in implementing protocols across diverse country contexts. Sites initiated activities in 2025 using catalytic funding from SEARO, complemented by the mobilization of internal national resources. The Institute of Epidemiology, Disease Control and Research (IEDCR), Bangladesh, reported the adoption and piloting of investigation protocols on non‑seasonal influenza and emerging respiratory diseases during recent avian influenza outbreaks, demonstrating a multi‑source funding approach involving government, WHO and One Health partners.The Hamdard Institute of Medical Sciences and Research (HIMSR), New Delhi, India, highlighted the piloting of household transmission investigation studies, the expansion of the national Unity Studies network, and the contribution of study findings to global evidence through published outputs. The All-India Institute of Medical Sciences (AIIMS), New Delhi, India, shared experiences from large‑scale seroprevalence studies conducted during the COVID‑19 pandemic, recent efforts to strengthen national Unity network sites through training activities, and plans to initiate multi‑centre studies on respiratory viruses.Similarly, Prince of Songkla University, Thailand, highlighted its experience in developing integrated surveillance and diagnostic protocols for multiple respiratory pathogens, enhancing readiness for targeted investigations of emerging threats. The University of Sri Jayewardenepura, Sri Lanka, reported ongoing engagement with the Ministry of Health and exploration of additional funding sources to initiate studies. Meanwhile, the National Public Health Laboratory, Nepal, provided updates on continued coordination with national stakeholders to initiate implementation, despite delays related to the country context.Across sites, shared experiences underscored the importance of protocol adaptation, multisectoral collaboration, and sustainable funding to operationalize Unity Studies and generate evidence for public health action.Discussions and Way ForwardThe meeting reinforced key priorities for 2026, including strengthening unity studies protocol implementation, enhancing collaboration, knowledge sharing, integrating research as a component of national multi-source surveillance systems, and ensuring that generated evidence informs public health decision‑making. Participants also emphasized the importance of documentation, visibility, and leveraging multiple funding sources, and agreed on the following action points.Unity Studies Sites and WHO Country Offices:Advance adoption and implementation of at least one Unity protocol, continuing activities initiated in 2025 with catalytic funding, supplemented with other sources of funding where feasible.Document site-specific experiences, outcomes, and lessons learned; participate in regional and global knowledge-sharing platforms including WHO webinars and the Community of Practice.Work closely with ministries of health to establish unified national platforms for translating generated evidence into national public health decision-making. WHO Country Offices may facilitate technical support and complementary, synergistic funding opportunities where feasible. WHO Regional OfficeCoordinate with WHO Country Offices to support implementation of core unity studies activities by network sites through catalytic funding and provide technical guidance and virtual engagement opportunities throughout 2026.Facilitate the participation of all Unity Studies sites in the regional meeting on Unity Studies implementation in October 2026, to be held back‑to‑back with the Annual SEAR Regional PIP‑PC Meeting; develop and host a SEAR Unity Studies website; and mobilize support from academic institutions within the SEAR Unity Studies Network to support the development of regional manuscripts that showcase Unity Studies activities to scientific audiences and promote knowledge‑sharing.Explore complementary funding opportunities and partnerships to sustain and expand network activities across the Region.WHO HeadquartersProvide global technical guidance, updated protocols, and toolkits to support the implementation of Unity Studies in SEAR.Facilitate engagement of SEAR sites in global webinars, the Community of Practice, and opportunities to showcase their work.Support joint publications, inclusion of SEAR experiences in global outputs, and identification of additional funding and collaborative opportunities to strengthen Unity Studies activities.
Sunday Politics: New studio means more choice for audience
The programme will be broadcast live on BBC One NI and for the first time on Radio Ulster and Foyle.
Apple Pushes Siri Programmers to Adopt AI Coding Tools
Apple plans to send “a significant chunk” of its Siri programmers to a weekslong bootcamp to learn to code using artificial intelligence, The Information
BBC News NI's Sunday Politics is getting a new look as it's available for the first time across the BBC
Mark Carruthers will present the multi-platform programme from a new studio home in Broadcasting House
The value of free health insurance: Evidence from Mexico’s Seguro Popular
Expanding free health insurance is central to universal health coverage, but its impact depends on how households value it. This column examines Mexico’s Seguro Popular and shows that households value the programme less than its fiscal cost. This helps explain why its effects on labour markets were modest and suggests that overall welfare gains may be smaller than often assumed, despite the programme’s large expansion in coverage.
Siri Engineers Sent to AI Coding Bootcamp as Apple Prepares to Deliver Siri Overhaul
Apple is sending a large portion of its Siri engineers to a multi-week bootcamp to learn to code using AI, reports The Information. Apple's decision to teach its programmers to better use AI for coding comes just two months before Apple is expected to unveil a smarter, more capable version of Siri at WWDC. While employees attend the coding bootcamp, around 60 members of the Siri development team will stick around to work on Siri, and an additional 60 will evaluate how Siri is performing.
Apple Sends Siri Staffers to Coding ‘Bootcamp’ in Latest Shakeup For Organization
Apple is sending a portion of its Siri programmers back to coding school just two months before the company is expected to unveil a major, AI-powered revamp of the voice assistant, people familiar with the team said. The company plans to send a significant chunk of people working on Siri—a group ...
Sparks and barks: College of Engineering and Science unveils robot dog
The Louisiana Tech University College of Engineering and Science (COES) has officially introduced its newest and most innovative ambassador: CHIP, a robotic dog enhanced and programmed by COES student
Shropshire new children's mental health service to tackle delays
The three year programme hopes to provide easier access, earlier support and more joined-up care.
Viewpoint: FP10 should remain open, excellent and secure
Europe is right to worry about research security. Foreign interference is real. So is the misuse of sensitive knowledge. Universities working in sensitive areas such as AI, quantum, semiconductors and advanced materials cannot afford to ignore the geopolitical environment around them.But Europe is in danger of drawing the wrong conclusion, one that would increase, not reduce, its strategic vulnerabilities.If the EU applies an “EU preference” logic to the next Framework Programme for research and innovation (FP10), it will weaken one of its greatest strategic assets: a research system built on openness, excellence and international collaboration. In the name of security, Europe could end up advancing science more slowly, innovating less effectively and making itself less attractive to global talent and partners in advanced science and technology.That would be a serious mistake.The EU preference included in Article 10 of the proposed European Competitiveness Fund may make sense in some industrial or deployment contexts, but is far harder to justify when applied to collaborative research in advanced science and technology, where excellence and global connectivity are crucial. Research is not procurement. It does not thrive when isolated. It advances through access to the best ideas, the best people, the best facilities and the best data, wherever they are found. This is why FP10 should not simply absorb industrial policy logic by default. Doing so would risk importing instruments that are ill-suited to research and that ultimately increase vulnerability rather than resilience.For universities of science and technology, the issue is especially acute. These institutions sit at the frontier of knowledge and technology creation in the very fields Europe sees as critical for its future competitiveness and resilience. They know better than most that security risks are real. But they also know that openness and security are not opposites. In practice, they have to be made to work together. Research security is not about closing doors. It is about building resilience through collective responsibility, trust, proportionate safeguards and better governance. That is a fundamentally different approach from default restriction.The risks of non-collaborationThe real danger in the current debate is that Europe talks too much about the risks of collaboration and not enough about the risks of non-collaboration. Those risks are strategic too. Cut researchers off from international networks and Europe loses access to knowledge, data, infrastructures and talent. Slow down global collaboration in critical technologies and Europe slows down its own progress on cutting-edge science. Make participation rules unpredictable and Europe weakens its attractiveness to researchers and investors alike.In other words, over-restricting collaboration will create strategic vulnerabilities, particularly in advanced science and technologies.This point is often underestimated in policy discussions that frame openness mainly as a value to be defended. Europe’s scientific strength, technological development and long-term competitiveness depend on remaining connected to the best research ecosystems in the world. For a continent that wants to accelerate deep tech, strengthen industrial capacity and reduce strategic dependencies, weakening the excellence base would be self-defeating. That does not mean ignoring risk. Quite the opposite. Universities are already strengthening due diligence, internal governance, awareness-raising, screening procedures and compliance support. Across Europe, institutions are working to manage risks linked to foreign interference, sanctions, export controls and the misuse of research. The right response is not complacency. It is better risk management. But that means targeted, evidence-based and proportionate measures, not blunt top-down restrictions with wide spillover effects. In the daily reality of universities, openness and restriction often coexist. The real challenge is how to apply safeguards without sliding into securitisation that damages academic freedom, open science and international cooperation. Restrict partners, not nationsMore restrictive treatment of collaborators from European Economic Area members Iceland, Liechtenstein and Norway, or from Switzerland and the UK, is strategically very difficult to justify. These are deeply embedded partners in Europe’s research and innovation ecosystem. Beyond that, Europe should still resist default exclusion and instead rely on case-by-case assessment. The relevant question is not nationality in the abstract. It is the actual risk profile of a collaboration: the institution, the affiliations, the field, the knowledge involved, the intended use and the safeguards available. Screening should focus on institutions and affiliations rather than nationality alone. Related articlesParliament ‘misreads’ link between Horizon Europe and ECF, Commission official saysFrustration grows at governance gap in next Horizon EuropeIf EU preference logic is imported into research without careful calibration, the likely result is a chilling effect. Researchers may step back from legitimate and beneficial collaboration, even where risks are manageable. International partners may see Europe as less predictable. And Europe may end up undermining the very excellence base it needs to compete, scale up and lead in strategic technologies, thereby increasing its dependence on others.FP10 should do the opposite. It should remain open by default, with restrictions used only exceptionally, and then on the basis of clear evidence. It should integrate research security into open science and research integrity frameworks, not set them against each other. And it should recognise that academic freedom, scientific excellence and responsible international collaboration are not obstacles to Europe’s security, they are part of it. Europe needs stronger tools to protect itself. But it also needs the discipline to avoid measures that would weaken it and increase its strategic vulnerabilities in the process. In FP10, that means staying open, excellent and secure.Louise Drogoul is senior advisor for innovation and sustainability at the Cesaer university association.
WHO calls for science-led action and stronger One Health approach to address evolving health risks
The World Health Organization today called for urgent scale-up of research, innovation, and collaboration to accelerate momentum towards ending tuberculosis in the WHO South-East Asia Region, which continues to bear nearly half of the global TB burden, accounting for the highest share of cases and deaths worldwide. To build momentum, experts, national TB programme managers, researchers, along with partners and members of civil society, began a three-day virtual workshop organized by WHO for ‘Advancing research and Innovation to accelerate momentum towards ending TB in the WHO South-East Asia Region.’
US health insurance shares jump as Trump administration boosts Medicare payments
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Lil Nas X assault case to be dismissed if he completes mental health programme
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90 Painfully Relatable Programming Memes That Might Just Break Your Brain (New Pics)
Every job has its quirks. But some feel almost like a world of their own. Like programming—we (indirectly) interact with it every day, yet many of us know surprisingly little when it comes to what actually goes on behind the screens. The subreddit ‘Programmer Humor’ is the perfect place to bridge this gap. It allows them—and pretty much everyone involved in computer science—to air their frustrations and give the rest of us a better understanding of what their day-to-day really looks like. Here a
WHO’s head of emergencies reaffirms support to Lebanon’s health system amid escalating needs
Lebanon’s health system continues to function despite the mounting pressures of conflict, displacement and repeated attacks on health care – but without urgent action and sustained international support, access to essential health services is increasingly at risk.
Epic's mass layoffs left a programmer with terminal brain cancer without life insurance, but Tim Sweeney says the company will "solve" the problem
A programmer with terminal brain cancer lost his life insurance due to Epic Games' mass layoffs, and Epic are now helping his family out.
Epic Games layoffs: developer with terminal brain cancer loses life insurance
Epic Games’ latest round of layoffs, which cut roughly 1,000 roles, has drawn renewed scrutiny after reports that a longtime programmer with terminal brain cancer lost his employer-sponsored life insurance immediately upon termination. While the company offered severance and six months of continued health coverage, the employee’s family says a pre-existing condition prevents obtaining new coverage, prompting outreach to Epic executives and an update that discussions are now underway.
Samsung Brings One UI 8.5 Beta Programme to More Galaxy Devices
Samsung is expanding the One UI 8.5 beta programme to additional Galaxy devices. Introduced with the Galaxy S25 series, Galaxy Z Fold7 and Galaxy Z
World TB Day: Scaling workplace healthcare interventions
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Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Ubisoft announces layoffs and the cease of game development at Red Storm Entertainment
The studio will remain open, but 105 people are being laid off as part of Ubisoft's cost reduction programme
German Health Minister Nina Warken and WHO Hub in Berlin highlight 2025 achievements
Germany’s Federal Minister of Health, Nina Warken, visited the WHO Hub for Pandemic and Epidemic Intelligence in Berlin today to review progress and launch its 2025 Annual Report. The report highlights advances in using artificial intelligence, data science and pathogen genomics to strengthen global preparedness for future pandemics.In 2025, the WHO Hub in Berlin worked with more than 160 Member States and over 190 partners to help countries and organizations develop new systems and tools to detect and understand new public health threats as quickly as possible, whenever and wherever they occur.BMG to confirm whether they wish to contribute a quote. “Detecting outbreaks early is one of the most effective ways to save lives and prevent epidemics from becoming global crises,” said Federal Minister of Health Nina Warken. “Germany is proud to host and support the WHO Hub for Pandemic and Epidemic Intelligence. Its work strengthens our safety at home and helps protect people worldwide.”Artificial intelligence is increasingly transforming the detection of outbreaks. In 2025, the Hub launched an upgraded version of the Epidemic Intelligence from Open Sources (EIOS) system, which uses enhanced AI functions to scan global online information in real time and help experts quickly identify unusual health events. The system is now used by 120 countries.To better anticipate health threats, countries need information beyond traditional health data. The Hub supports countries in implementing Collaborative Surveillance, which integrates data on climate, animals, travel, and population movement to provide a more comprehensive and real-time understanding of health threats.The Hub also expanded global access to pathogen genomics, which helps scientists detect new pathogens, such as viruses and bacteria, understand how they spread and how dangerous they may become. Through the International Pathogen Surveillance Network (IPSN), the WHO Hub in Berlin worked with 309 partners in 101 countries to expand access to these technologies.“We are in a new era of global health threats, and we need new tools to face tomorrow’s challenges,” said Dr Chikwe Ihekweazu, Executive Director of the WHO Health Emergencies Programme. “The WHO Hub in Berlin helps countries use data and technology more effectively so they can identify risks earlier and respond faster. No country can address these threats alone. Strong cooperation remains our best defence.”“Berlin offers an ideal environment for our work. We collaborate closely with world-leading institutions such as the Robert Koch Institute and the Charité Center for Global Health,” said Dr Oliver Morgan, Head of the WHO Hub for Pandemic and Epidemic Intelligence. “Germany has supported the WHO Hub since its establishment, and we are pleased to welcome Federal Minister Nina Warken to the Hub today. This strong partnership helps us advance innovation in pandemic and epidemic intelligence and better support countries to prepare for future health threats.”The Hub is expanding the use of advanced analytics and mathematical modelling to forecast how outbreaks may develop and to assess which response measures are most effective. Through its Collaboratory, the Hub connects modelers and analysts with governments to ensure their work addresses real public health needs. In 2025, the community grew to 1300 members from 50 countries and 200 institutions. An AI-powered pandemic simulator, currently in the prototyping phase, will help decision-makers compare outbreak scenarios and help identify effective disease control measures.
Leading Chinese remote-sensing scientist Zhang Jinshui dies at 47
Beijing Normal professor led major R&D programmes and was instrumental in enhancing the country’s food security with satellite technologies.
Strengthening One Health Field Epidemiology Capacity in the WHO South-East Asia Region
Recent public health emergencies—including the COVID-19 pandemic, recurrent zoonotic disease outbreaks, and the high level of antimicrobial resistance—have underscored the urgent need for strong, multisectoral field epidemiology capacities. This reinforces the importance of a workforce equipped with One Health field epidemiology competencies. To address this need, WHO works with the Food and Agriculture Organization of the United Nations (FAO), the United Nations Environment Programme (UNEP), and the World Organisation for Animal Health (WOAH), as part of Quadripartite Alliance for One Health, to strengthen field epidemiology training programmes using a One Health approach.These efforts are aligned with WHO SEARO’s Strategic Framework for Action for Strengthening Surveillance, Risk Assessment and Field Epidemiology and the Regional Roadmap to Advance Field Epidemiology Capacities 2025–2029 emphasize workforce development, multisectoral collaboration, and enhanced preparedness for health emergencies. With funding from the Pandemic Fund, The Competency for One Health Field Epidemiology (COHFE) integration within Field Epidemiology Training Programmes (FETPs) or similar initiatives has been initiated in Bangladesh and India and is planned in Sri Lanka.BangladeshIn Bangladesh, COHFE is being adapted to strengthen the Field Epidemiology Training Programme, Bangladesh (FETP-B) Advanced programme. Initiated in July 2025 and led by the Institute of Epidemiology, Disease Control and Research (IEDCR), the process brought together stakeholders from human, animal, and environmental health sectors, academia, and laboratories.A Multisectoral Working Group (MWG) was established to guide implementation, conduct readiness assessments, and identify opportunities to institutionalize One Health collaboration. Through national multisectoral consultations and a competency prioritization workshop held in Dhaka in November 2025, stakeholders identified priority technical competencies for surveillance, outbreak investigation, data analysis, and risk assessment, alongside functional competencies related to leadership, coordination, and the laboratory–epidemiology interface. The process also surfaced systemic barriers—such as challenges in data sharing and limited joint investigations—enabling targeted recommendations. These outcomes are guiding curriculum revision, the introduction of One Health simulations and joint field exercises, and the development of a national multisectoral mentorship pool, with updated training materials expected to be implemented in the upcoming cohort.Figure 1. Competency prioritization involving multisectoral stakeholders“COHFE represents a significant step forward in operationalizing the One Health approach. The collaboration between national institutions and the Quadripartite partners is critical for building resilient systems to address complex health challenges in the region.”, Prof. (Dr) Tahmina Sirin, Director, Institute of Epidemiology, Disease Control and Research (IEDCR), Bangladesh.Aligning India’s One Health Training with COHFEIn India, the National Centre for Disease Control (NCDC) has strengthened One Health workforce development through its SectorConnect initiative. WHO supported a comprehensive competency mapping and curriculum review to align the Field Epidemiology Programme in One Health (FEP-OH) with all 14 COHFE domains. The review identified strong foundations while generating actionable recommendations to strengthen One Health learning outcomes, expand joint field-based learning, and enhance competency-based assessment. These improvements are informing programme refinement and phased scale-up across additional states.Figure 2. Strengthening learning outcomes for the SectorConnect FEP OH CurriculumThrough these efforts, WHO SEARO will continue to support countries to move from separate sector-based training toward an integrated, impact-driven One Health field epidemiology workforce capable of addressing complex health threats at human-animal-environment interface.ReferencesFood and Agriculture Organization of the United Nations, World Health Organization, & World Organisation for Animal Health. (2024). Competencies for One Health field epidemiology (COHFE) framework. https://www.who.int/publications/i/item/9789240080058World Health Organization. (2023). Strategic framework for action for strengthening surveillance, risk assessment and field epidemiology for health security threats in the WHO South-East Asia Region. WHO Regional Office for South-East Asia. https://www.who.int/publications/i/item/9789290210030World Health Organization. (2024). Regional roadmap to advance field epidemiology capacities in the WHO South-East Asia Region 2025–2029. WHO Regional Office for South-East Asia. https://www.who.int/publications/i/item/9789290229544
CERN Science Gateway celebrates its 1000th science show
CERN Science Gateway has reached another milestone: the delivery of its 1000th science show! Since opening its doors in October 2023, Science Gateway has welcomed nearly 900 000 visitors of all ages to explore the fundamental questions of the Universe. Among its most popular activities are the science shows – dynamic, interactive demonstrations led by CERN guides and tailored to a broad audience of different age levels, including school groups, families and the general public. Designed to make complex scientific concepts accessible and entertaining, these live shows combine spectacular experiments, multimedia elements and audience participation. From the physics of particle collisions to the properties of superconductivity, electromagnetism and cryogenics, the science shows translate the research carried out at CERN into engaging visual experiences. Visitors might see superconductors levitate, follow particles through different detector layers or discover the beauty in phase transitions. Each demonstration is carefully crafted to spark curiosity while maintaining scientific accuracy. Members of the CERN community are of course warmly invited to visit CERN Science Gateway with their family or friends and attend one of the science shows. To register, please visit this page, and don’t forget to check the programme for the coming days. Become a CERN guide and run your own super-cool science show (and more)! To become a CERN guide, you can join the introduction course held every 3–4 weeks, which will give you an overview of what being a CERN guide entails. From there, further courses are available depending on what type of guide you would like to be. Because, of course, CERN guides are needed everywhere at CERN. If you imagine yourself as a more ‘traditional’ guide, you should know that there are currently more than ten exciting visit points in CERN’s visits portfolio, such as the Antimatter Factory, the ALICE experiment (surface), the Alpha Magnetic Spectrometer (AMS) control room, the ATLAS experiment (surface), the CERN Control Centre (CCC), the Data Centre, the LHCb experiment (surface), the Synchrocyclotron (SC), the SM18 test facility and the newly inaugurated Linac2 visit point. Indeed, CERN’s Visits Service and Visual Impact and Exhibitions Section recently collaborated on redesigning the Linac2 visit tour, which has just reopened to the public after several months of renovation work. The new tour offers visitors and guides alike an enriched, more immersive experience, designed to highlight the history and scientific significance of this major facility. So, fancy becoming one of the insiders? Join the introduction course, check the guides website or contact guides.manager@cern.ch. And remember, becoming a guide can benefit you, too.
US science budgets have been spared. So why is no one celebrating?
The Trump administration’s proposals to eviscerate the NIH and NSF have been overturned in Congress after a year of cancelled programmes and legal wrangling. Yet as funding continues only to dribble out of downsized and politicised agencies, few believe that US science is out of the woods yet
Budget cuts at Environment and Climate Change Canada threaten Arctic science
For decades, ECCC research scientists have been integral to the work of the Arctic Monitoring and Assessment Programme.
Pollution and mental health: current scientific evidence
This briefing discusses the evidence that is currently available on the associations between environmental pollution and mental health. It is based on a review of the scientific literature, and it supports the zero pollution action plan (ZPAP) and the European Union’s (EU’s) Eighth Environment Action Programme (8 th EAP). Related content can be found here: Climate change impacts on mental health in Europe ; Impact of air pollution on mental health (signal) .
Your morning coffee could one day help fight cancer
Scientists at Texas A&M are turning an everyday pick-me-up into a high-tech medical switch. By combining caffeine with CRISPR gene editing, researchers have created a system that allows cells to be programmed in advance — and then activated simply by consuming a small dose of caffeine from coffee, chocolate, or soda. The approach, known as chemogenetics, lets scientists precisely turn gene-editing activity on and off inside targeted cells, including powerful immune T cells that can fight cancer.
UN World Food Programme Chief Cindy McCain to Step Down for Health Reasons
ROME, Feb 26 (Reuters) - Executive Director of the United Nations World Food Programme (WFP) Cindy McCain plans to step down from the role in three months to focus on her health, she said on Thursday. The 71-year-old widow of the late U.S. Republican Senator John McCain suffered a mild ...
UN food chief Cindy McCain to step down over health concerns
The U.N. World Food Programme’s executive director, who suffered a mild stroke last year, will leave her post in three months as the agency battles deep funding cuts and record global hunger.
US re-asserts 2025 strikes ‘obliterated’ Iran’s nuclear programme
The White House comment comes after a senior Trump aide said Iran is a week away from having material for nuclear bomb.
Scientists engineer bacteria to eat cancer tumors from the inside out
Researchers are engineering bacteria to invade tumors and consume them from the inside. Because tumor cores lack oxygen, they’re the perfect breeding ground for these microbes. The team added a genetic tweak that helps the bacteria survive longer near oxygen-exposed edges — but only once enough of them are present to trigger the change. It’s a carefully programmed biological attack that could one day offer a new way to destroy cancer.
PRET for impact: Advancing pandemic preparedness in the Democratic People’s Republic of Korea
IN THE SPOTLIGHT PRET for impact: Advancing pandemic preparedness in the Democratic People’s Republic of KoreaThe Democratic People’s Republic of Korea (DPR Korea) is making significant progress in strengthening pandemic preparedness, with dedicated support from the WHO South‑East Asia Regional Office (SEARO) and the Pandemic Influenza Preparedness (PIP) Partnership Contribution (PC).Aligned with the WHO Global Influenza Strategy and the Pandemic Influenza Preparedness (PIP) Framework Partnership Contribution High‑Level Implementation Plan III (2024–2030), the country is strengthening its capacity to prepare for and respond to influenza and other respiratory threats. In early 2025, a core team from the Ministry of Public Health of the Democratic People’s Republic of Korea (DPRK) participated in a two‑day virtual workshop, which included a mini‑simulation exercise. The workshop was organized by WHO SEARO in collaboration with the Preparedness and Resilience for Emerging Threats (PRET) Secretariat at WHO headquarters and the WHO Country Office for the DPRK. Read more A REGIONAL CONSULTATION GUIDES WHO SEARO IN DEVELOPING A ROADMAP FOR IMPLEMENTING THE PREPPAREDNESS AND RESILIENCE FOR EMERGING THREATS (PRET) INITIATIVE BASED RESPIRATORY PATHOGEN PANDEMIC PREPAREDNESSInfluenza and other respiratory pathogens with pandemic potential continue to pose major public health risks globally. To strengthen regional preparedness and response, Member States of the WHO South‑East Asia Region (SEAR) convened in Colombo, Sri Lanka, to review and provide input on the draft Roadmap and Action Framework for Broad Respiratory Pathogen Pandemic Planning (2026–2031). Supported through the Pandemic Influenza Preparedness (PIP) Partnership Contribution (PC) funds, the proposed roadmap aims to advance robust, integrated preparedness and response capacities for influenza and other respiratory threats across SEAR. This work is aligned with the Preparedness and Resilience for Emerging Threats (PRET) initiative and the SEAR Strategic Roadmap on Health Security and Health System Resilience for Emergencies Read moreSRI LANKA’S USE OF ANTIVIRALS TO REDUCE THE SEASONAL INFLUENZA BURDEN Sri Lanka is strengthening its influenza response by placing greater emphasis on rapid testing, timely treatment, and integration with maternal health services. With support from WHO, the country is building a stronger evidence base on the burden of influenza and the value of vaccination, advancing a holistic approach to protect vulnerable populations and enhance pandemic preparedness. To reduce hospitalizations and deaths from seasonal influenza, Sri Lanka is taking proactive steps to expand access to rapid diagnostic testing and ensure prompt initiation of treatment. National clinical guidelines recommend the use of oseltamivir for individuals at high risk of complications, helping prevent severe illness and shorten the duration of infection. This strategy not only saves lives but also supports local pharmaceutical production, contributing to a reliable supply of antivirals for both seasonal outbreaks and future pandemics.Read moreBHUTAN BOOSTS PANDEMIC INFLUENZA READINESS WITH PANDEMIC INFLUENZA PREPAREDNESS FRAMEWORK PARTNERSHIP CONTRIBUTION SUPPORTED TRAINING AND SIMULATIONSOriginally developed in 2012, the National Influenza Pandemic Preparedness and Response Plan (NIPPRP) has long served as Bhutan’s central framework for managing influenza threats. In 2024, the plan underwent a comprehensive update to reflect evolving global and regional guidance, lessons learned from the COVID‑19 pandemic, and new capacities developed under the PIP Framework. The revised NIPPRP is now more clearly aligned with Bhutan’s broader emergency and disaster risk management structures, ensuring a coordinated, whole‑of‑government approach to pandemic response. As part of efforts to strengthen national pandemic preparedness, Bhutan conducted three national‑level training sessions followed by simulation exercises on influenza pandemic preparedness and response at five sentinel hospitals between April and May 2025, with support from the PIP Partnership Contribution (PC). These activities brought together more than 140 health professionals and key partners from across the country, with a focus on operationalizing the updated NIPPRP and enhancing readiness at key frontline facilities. Read moreSTRENGTHENING INFLUENZA SURVEILLANCE: WHO BRINGS TOGETHER INFLUENZA EXPERTS FROM SOUTH-EAST ASIA AND WESTERN PACIFIC REGIONSThe World Health Organization (WHO) convened the 18th Bi‑regional Meeting of National Influenza Centres (NICs) and Influenza Surveillance for the WHO South‑East Asia and Western Pacific Regions from 9–11 September 2025. Hosted by the WHO South‑East Asia Regional Office (SEARO), the meeting brought together representatives from Member States, Territories, and Areas across both regions, alongside experts from the WHO Collaborating Centres for Reference and Research on Influenza in Australia and Japan, the WHO Collaborating Centre for Studies on the Ecology of Influenza in Animals in the United States, quadripartite partners (WOAH and FAO), and other technical counterparts. The consultation provided a platform to review progress, share experiences, and outline priorities for strengthening influenza and respiratory pathogen surveillance across the two WHO regions.Read moreNETWORKS AND TECHNICAL PARTNERSHIPSSTRENGTHENING PANDEMIC READINES: SOUTH-EAST ASIA ADVANCES UNITY STUDIES UNDER THE PANDEMIC INFLUENZA PREPAREDNESS INITIATIVEThe WHO Global Influenza Surveillance and Response System (GISRS) Investigations & Studies initiative, also known as Unity Studies, provides a standardized, globally coordinated framework to support these efforts. Originally developed for influenza and adapted during COVID-19, Unity Studies enable countries to conduct rapid, nationally led investigations and studies to assess transmissibility, severity, susceptibility, and intervention effectiveness. To better prepare for future influenza pandemics, WHO has recently launched a network of sites which will be ready to conduct these investigations and studies rapidly in the event of a pandemic, or epidemic of an emerging or re-emerging respiratory pathogen. The WHO South-East Asia Region now hosts six sites of WHO GISRS Unity Studies across the five countries including Sri Lanka, strengthening regional capacity for early pandemic investigations. From 13–16 July 2025 in Colombo, the Global Public Health Summit offered an opportunity to advance this agenda. Read moreSTRENGTHENING PANDEMIC PREPAREDNESS THROUGH UNITY STUDIES: REAL-WORLD APPLICATIONS FROM INDIA IN WHO’S SOUTH-EAST ASIA REGION As countries continue to strengthen their pandemic preparedness through investments in resilient health systems during the interpandemic period, the World Health Organization’s (WHO) Global Influenza Surveillance and Response System (GISRS) Investigations & Studies Global Initiative, Global Initiative, commonly known as Unity Studies, remains a vital framework for respiratory pathogen pandemic preparedness. These standardized epidemiological protocols enable countries to rapidly generate high‑quality data on transmissibility, infection severity, population immunity, and the effectiveness of public health interventions. To highlight how Unity Studies protocols are being adapted and applied in national settings, WHO Headquarters, together with WHO Regional Offices, including the WHO South‑East Asia Regional Office (SEARO), hosted a global webinar. The session showcased case studies from India and the United Kingdom (UK), demonstrating innovative approaches to respiratory virus surveillance and pandemic readiness. Read moreSTRENGTHENING REGIONAL INFLUENZA SURVEILLANCE AND PREPAREDNESS: WHO SEARO HOSTS HIGH-LEVEL WEBINAR AMID RISING H5 THREATS In response to the increasing detection of avian influenza A(H5) cases in humans globally and within the WHO South‑East Asia Region, the WHO Regional Office for South‑East Asia (SEARO) convened a regional webinar on 25 July 2025 to review preparedness mechanisms, strengthen surveillance pathways, and promote timely reporting of unusual respiratory events. The virtual session brought together more than 50 participants from Ministries of Health, National Influenza Centres (NICs), National IHR Focal Points (NFPs), WHO Headquarters, WHO Country Offices across the Region, and WHO Collaborating Centres (CCs) for influenza. The webinar provided an opportunity to share situational updates, discuss surveillance gaps, and reinforce coordination mechanisms critical for early detection and rapid response to avian influenza threats. Read moreOther Key PIP Updates (July-December 2025)MEMBER STATES:Bangladesh drafted and conducted a series of Core Group Meetings in 2025 to review and update the National Pandemic Preparedness and Response Plan for Respiratory Pathogens. In addition, the country carried out Rapid Response Team (RRT) trainings on seasonal and avian influenza and other re‑emerging infectious diseases. Bangladesh also updated its epidemiological data‑training programme for physicians at sentinel surveillance sites, using a revised epidemiological data‑collection tool.Bhutan revised and updated its National Influenza Pandemic Preparedness and Response Plan (NIPPRP) in 2025 and developed a national Standard Operating Procedure (SOP) for influenza outbreak management. DPR Korea conducted a nationwide simulation exercise in July 2025 to support the update of its National Influenza Pandemic Preparedness Plan (2019). This followed a PRET‑based virtual orientation and mini‑simulation exercise held in May 2025 by SEARO and the WHO PRET Secretariat. The comprehensive exercise, conducted across central and provincial levels, assessed strengths and gaps in pandemic influenza preparedness and response. The feedback gathered has been incorporated into the revised draft plan to address identified weaknesses and strengthen overall readiness.India conducted a targeted nationwide online re‑orientation training on review and updates to the influenza portal for all State Surveillance Officers (SSOs) and relevant officials using the Integrated Health Information Platform (IHIP). The training emphasized correct marking and reporting of influenza samples as “unsubtypable” or “not subtyped” where applicable, to ensure accurate national surveillance.Maldives conducted simulation exercises in three atolls based on its existing National Pandemic Preparedness and Response Plan (NPPRP). The country plans to conduct similar exercises in three additional atolls after updating the NPPRP in 2026. In addition, Maldives conducted training on FluID and FluMart as part of a broader data‑management training package for Ministry of Health and Health Protection Agency officials, aimed at improving routine reporting to WHO platforms and the DHIS2 system.In Myanmar, technical support was provided to the National Influenza Centre (NIC) through dedicated human‑resource support (January–December 2025) to sustain data management and laboratory detection capacity for influenza and other emerging and re‑emerging respiratory viruses. This support also included strengthening genomic sequencing capacity.Nepal conducted a consultative workshop on the National Pandemic Preparedness and Response Plan (NPPRP) in July 2025. The workshop engaged key stakeholders from multiple sectors to review lessons from past pandemic responses, assess current mechanisms, and gather critical inputs for strengthening national preparedness. Key recommendations included revising the 2019 NPPRP and developing an updated Influenza Pandemic Preparedness Plan aligned with emerging risks, national priorities, and relevant international frameworks. Nepal also held a two day workshop dedicated to advancing the National Action Plan for Genomic Surveillance, aimed at reinforcing the country’s capacities for early detection and monitoring of emerging respiratory pathogens.Sri Lanka received the final report from WHO on the feasibility assessment for conducting an Influenza Burden of Disease (BoD) study in the country. The assessment, conducted from 28 April to 9 May 2025, included a desk review of existing data sources, document review, visits to sentinel surveillance sites, and key informant interviews. The study identified critical data sources required for a future BoD assessment, as well as their availability and quality. Officials from the Epidemiology Unit, the National Influenza Centre (NIC), and SARI/ILI sentinel hospitals across the country participated in the assessment.Timor Leste conducted on‑the‑job training and monitoring activities at two sentinel surveillance sites to strengthen surveillance and laboratory capacity for the detection of SARI, ILI, ARI, and other respiratory infections. REGIONAL OFFICE:SEARO conducted a Member States Consultation on the first draft of the Regional Roadmap and Strategic Action Framework for implementing WHO’s PRET‑based broad respiratory pathogen pandemic planning for 2026–2031. The consultation took place on 29–30 October 2025 during the final two days of the Regional PIP PC Annual Review and PRET Meeting in Colombo, Sri Lanka. Participants included representatives from Member States, WHO Country Offices, WHO SEARO, WHO Headquarters, partner agencies, and invited multidisciplinary technical experts. They reviewed the draft and provided detailed feedback, which has since been incorporated into a revised version. The consultation helped shape a shared regional vision for robust, PRET‑aligned pandemic preparedness, building on country‑level progress, addressing existing gaps and challenges, and aligning with global and regional health security frameworks. The publication is planned for release during the SEAR regional committee in 2026.SEARO documented the evolution of the National Influenza Pandemic Preparedness Planning process in the Region, tracing its development from its origins as a planning tool for responding to avian influenza outbreaks in 2006, through the experiences of the 2009 and 2019 pandemics, to the current status. The document outlines the way forward for respiratory pathogen pandemic planning across all 10 SEAR countries, aligning future national plans with WHO’s PRET Framework for broad respiratory pathogen pandemic preparedness.The Infectious Hazard Management (IHM) Unit has drafted the WHO South‑East Asia Regional Guidance on Influenza Prevention and Control, aligned with the Global Influenza Strategy and other regional initiatives. The draft is currently under review. Although this technical product was developed in response to a request from the Ministry of Public Health of the Democratic People’s Republic of Korea (MoPH‑DPRK), SEARO is finalizing it for use not only in DPRK but also across all Member States in the Region.The Immunization and Vaccine Development (IVD) Unit, in collaboration with WHE/SEARO, completed a regional landscape analysis on key barriers, challenges, and opportunities for the introduction of seasonal influenza vaccination in WHO South‑East Asia Regional (SEAR) countries.Additionally, the Immunization and Vaccine Development (IVD) Unit has completed a regional landscape analysis of influenza vaccine procurement systems across the WHO South‑East Asia Region (SEAR).KEY MEETINGS AND PUBLICATIONSMEETINGS:Six-month progress review of the implementation of the PIP-PC workplans in SEAR, focusing on Outputs 1 and 2 for the period January to June 2025, and held virtually across three sessions on 4, 8, and 10 July 2025. Read moreAnnual Regional Meeting (Hybrid) on Pandemic Influenza Preparedness (PIP) Partnership Contribution (PC) and WHO’s Preparedness and Resilience for Emerging Threats (PRET) Implementation in SEAR in Colombo, Sri Lanka, 27 to 30 October 2025. Read more18th Bi-regional Meeting (Virtual) of National Influenza Centres (NICs) and influenza surveillance in WHO South-East Asia and Western Pacific Regions from 9 to 11 September 2025. Read morePUBLICATIONSImplications of influenza A virus surveillance in Southeast Asian Region countries: a scoping review of approaches for the surveillance of swine influenza viruses at human-swine interfaces. Read moreAnnual South-East Asia regional meeting on operational planning for implementation of global influenza strategy and preparedness for respiratory viruses in 2025 Report on annual review meeting of implementation of pandemic influenza preparedness (PIP) partnership Contribution (PC) Fund in South-East Asia Region and the simulation exercise on PRET Status of influenza in who south-East Asia Region
More advanced maths students needed for tech sector: Hong Kong committee head
Government will review admission score calculation for some universities’ science, technology, engineering, arts and mathematics programmes.
Club launches 'world-first' souvenir programme
The Hornets scrapped its traditional matchday programme last year due to poor sales.
Trump weighs strikes as he gives Iran ‘10 to 15 days’ to agree deal over nuclear programme
The US has amassed an arsenal of military assets in the Middle East that would allow it to launch an aerial bombing campaign against Iran
UN agency begins clearing huge Gaza City waste dump as health risks mount
The United Nations Development Programme began clearing a huge wartime garbage dump on Wednesday that has swallowed one of Gaza City’s oldest commercial districts and is an environmental and health risk.
Markets brace for US jobs report, with White House telling investors ‘they shouldn’t panic’
Trump adviser Peter Navarro says ‘we have to revise our expectations down’ because of US deportation programme
When immune cells stop fighting cancer and start helping it
Scientists have uncovered a surprising way tumors turn the immune system to their advantage. Researchers at the University of Geneva found that neutrophils—normally frontline defenders against infection—can be reprogrammed inside tumors to fuel cancer growth instead. Once exposed to the tumor environment, these immune cells begin producing a molecule called CCL3 that actively promotes tumor progression.
Making science more visible
As he enters a laboratory with saltwater pools full of fish, Luka Žuvić explains how climate change is affecting the feeding ecology and reproductive biology of Atlantic bluefin tuna, and how the species is adapting.It is a topic that may seem remote to many people. But in a country where fishing and aquaculture are important to the economy and national identity, Žuvić’s research is at the intersection of science and society. “In Croatia, marine and environmental science are closely connected to people’s lives because fisheries, aquaculture, tourism and coastal development are a big part of our lives,” explains Žuvić, a doctoral student working at the Croatian Institute of Oceanography and Fisheries in the Adriatic coastal city of Split. He also serves as one of Croatia’s ambassadors to Science Comes to Town (SCTT), a European Commission-funded project that aims to make scientific research more accessible, while inspiring young people to study the sciences. The project kicked off in Spilt on 20 January with a conference attended by partner institutions, community representatives, policymakers and scientists. Along with Split, Brest (in France) and Kiel (in Germany) will host a year of activities connecting scientists with the public.Žuvić, 31, is part of the Young Researchers' Career Development Project, a doctoral programme funded by the Croatian Science Foundation. His research on Atlantic bluefin tuna builds on a foundation-backed project focusing on the reproductive potential of farmed tuna, including their sexual maturation and spontaneous spawning in captivity, which has implications for the restoration of the Adriatic Sea's natural tuna populations. He also studies the tuna's feeding ecology through stomach-content analysis, using DNA metabarcoding and morphological approaches, and employs geometric morphometrics to improve the identification of juvenile tuna and related species. The research aims to enhance understanding of the tuna farming ecology, improve fish farm management and contribute to sustainable aquaculture and fisheries research.Engaging with local communitiesConnecting with the community is crucial for Žuvić’s research. Conversations with fishermen help him better understand the bluefin tuna's habits and how marine pollution affects the fish. “They are also curious about the biology and ecology of bluefin tuna,” he says of local fishermen, adding that sharing research with non-scientists benefits everyone. “Sometimes scientific research is invisible,” he explains. “That's why we as researchers need to go out from our institutions and labs to the public so that we can show them what we are working on. This helps create more trust in the scientists and their research.”Engaging the public also raises awareness about the anthropogenic changes to the marine environment resulting from human activities and pollution. Žuvić helps remove plastic and other rubbish from the Adriatic Sea that pose a direct threat to marine species. Predators, such as bluefin tuna, are especially vulnerable to ingesting waste churned up by fishing trawlers. “They are very opportunistic fish that follow trawlers and ingest everything,” he notes. To illustrate the impact, he has shown students the contents of bluefin tuna stomachs. “Finding a plastic bottle cap in the stomach of a bluefin tuna is concerning,” he says. "Science can be a powerful way to turn curiosity into practical solutions,” Žuvić adds, and sharing research outcomes “helps increase public awareness and improve understanding of human impacts on the marine environment.”The research also has implications for Croatia's economy. The Atlantic bluefin tuna’s rich, flavourful meat is highly valued for sushi and other raw fish dishes. However, overfishing nearly brought its population to collapse by the early 2000s. Although the species has made a comeback in the Atlantic and Mediterranean regions, catches continue to be managed through agreements with the International Commission for the Conservation of Atlantic Tunas. Croatia was a pioneer in developing commercial aquaculture as an alternative to open-sea fishing and accounts for about 10% of the EU’s farmed production of the bluefin tuna, with Japan being a key export market.A history of European collaborationCroatia has participated in Europe’s framework programmes for research and innovation since 2007, six years before officially joining the EU. Žuvić believes that EU funding and collaboration with other European researchers is vital for Croatian science. As part of the SCTT opening conference, the Institute of Oceanography and Fisheries, the University of Split and other local institutions were part of a science fair to showcase research on topics, such as robotics and an EU LIFE project on the protection of sharks and rays in the Mediterranean. “I hope that Science Comes to Town will help increase scientific literacy and curiosity among citizens, particularly students, and show that science is not something that is distant or abstract, but something that directly affects everyday life,” Žuvić concludes. “Ultimately, I hope that projects like it contribute to building a society that values knowledge and critical thinking, and that we can think about long-term sustainability using knowledge from science.”Science|Business, which connects policymakers, academics and industry through its news reporting, analysis and events, is an SCTT partner.
International science cooperation must go on, say research leaders
Science leaders in Europe and Canada say international cooperation must go on amid geopolitical turmoil. At the same time, Europe and like-minded countries should continue to enhance and diversify international partnerships, a Science|Business conference hears. Hugh Brady, president of Imperial College London, told delegates that Europe’s response to the current geopolitical climate should be to “diversify in terms of research partnerships and build resilience and scale into our own system.”A first priority should be for the EU to sort out the scope of the upcoming European Competitiveness Fund and ensure that, together with the next iteration of Horizon Europe, it can drive the development and scale up of new technologies. The EU and the countries associated to the Horizon Europe programme represent “the world's most successful research innovation ecosystem,” Brady said. In order to mitigate the negative effects of shifting geopolitics, the EU together with the UK, Switzerland, Canada, South Korea and others should talk about “building resilience” and address their own “regional needs,” he added. Responding to TrumpUnder Donald Trump’s leadership, the US government has slashed science budgets and shut down international research programmes. Nearly 8,000 grants at the National Institutes of Health and the National Science Foundation have been frozen or terminated. Courts have overturned most of these cancellations, but the disruption caused remains significant. While Europe may persuade a few thousand disgruntled scientists to move across the ocean to work on topics that have been de-funded in the US, it’s unclear what should happen next with transatlantic scientific cooperation more broadly.“Now is the time for us to show [US researchers] our support as much as we can,” Brady said.The European Research Council (ERC), the EU’s basic science funder, has seen a surge in applicants from the US. According its latest data, US-based researchers submitted 347 proposals to the last three big funding rounds, up from 158 in the previous set of calls. The European Commission has also launched a €22.5 million pilot call in 2025 for the Marie Skłodowska Curie Actions, the EU’s researcher training scheme. It plans to extend this support with a €51.25 million call in 2027 as part of the Choose Europe initiative, which is intended to make the continent a more attractive place to pursue a career in research. Related articlesData corner: US researchers are choosing EuropeEU-India deal highlights growing alignment on technology policyMeanwhile, in the private non-profit sector, the Volkswagen Foundation is experimenting with a new type of grant that would allow US researchers to split their time between the US and Germany. While these schemes are useful, Europe should not bet on an exodus of scientists from the US. “The idea that we might all see them flocking over to Europe is naïve and counterproductive,” said Maria Leptin, president of the ERC, also speaking at the Science|Business conference on February 5. “We need research in the US to be as healthy as possible. I really admire those who are staying there with a will to fight and an optimism that the world will turn into a better place again,” Leptin said. Preserving dataDespite political disruption, academics have found ways to continue cooperating and sharing research data. Leslie Weir, president of the International Federation of Library Associations and Institutions and Canada’s national librarian, said the US cuts have raised concerns about research data security, after ideologically sensitive databases were limited or deleted by the Trump administration. But international organisations teamed up to ensure that the data is not lost. “It's interesting to see that researchers and libraries across North America are collaborating to make sure that data at risk is duplicated elsewhere outside [the US],” Weir said.
Joint statement on the renewed Quadripartite Memorandum of Understanding regarding cooperation on One Health until 2030
Through the renewal of the Memorandum of Understanding (MoU) on One Health, the Food and Agriculture Organization of the United Nations (FAO), the United Nations Environment Programme (UNEP), the World Health Organization (WHO), and the World Organisation for Animal Health (WOAH) reaffirm their shared commitment to advancing the implementation of the One Health approach.
From war damage to heart repair: ERC grantees supported to turn their science into practice
The European Research Council (ERC) has published the outcomes of the last 2025 round of its Proof of Concept Grants. In this round, 136 grantees will each receive €150 000, supporting them in exploring how their scientific results can move towards practical application or early commercial use. With these awards, the total number of Proof of Concept Grants under the ERC 2025 Work Programme reached 300, representing an overall budget of €45 million. The scheme is funded under Horizon Europe, the EU’s framework programme for research and innovation.
The challenges facing Alpine ahead of F1 2026
It’s a new era at Alpine, after Renault’s engine programme ended
The Val di Fiemme is transformed into a large cultural and entertainment stage for the Milan Cortina 2026 Winter Olympic Games
Concerts, exhibitions, DJ sets, fan parades and cultural events: the complete programme that will liven up the valley during the Winter Games.
A mental health hospital's 200 years of care in Oxford
The Warneford Hospital is holding a year-long programme of events to mark its bicentenary.
Western Pacific Region achieves milestone: 19 countries complete comprehensive health information system assessments
The Health Information and Digital Health (HID) unit in the WHO Regional Office for the Western Pacific has successfully supported 19 countries, covering 99% of the Region’s population, to conduct comprehensive health information system (HIS) assessments, surpassing the regional target of 15 set for 2025 and advancing efforts toward universal health coverage. Using SCORE, a technical package of essential interventions, recommended actions, tool and resources developed by WHO and partners to address challenges in meeting HIS needs, these assessments systematically assess health data availability and quality, enabling countries to monitor trends, identify and respond to emerging health challenges, and improve policies and programmes for healthier families, communities and societies. The first round of SCORE assessments were conducted between 2019-2021 in 14 countries in the Region and over 130 countries globally. The second round of SCORE assessments were conducted between 2024-2025.SCORE assessments are a key priority identified by Member States and WHO at all levels, including within WHO-Country/Multi-Country Cooperation Strategies, the Regional Vision Weaving Health for Families, Communities and Societies in the Western Pacific Region (2025–2029), and the WHO Fourteenth General Programme of Work (GPW 14, 2025–2028). Within the Regional Vision, implementing SCORE assessments is a key action for technology and innovation to advance health equity (strand 5).The SCORE for Health Data technical package is based on five key interventions, represented by the acronym SCORE. Interventions S, C and O focus on strengthening core data sources. Survey (S) covers population-based health surveys, surveillance systems and censuses, including their capacity to monitor health-related SDGs. Count (C) focuses on birth, death and cause of death registration as parts of a functional CRVS system. Optimize (O) addresses routine health service data and key health service inputs such as health financing and health workforce.Interventions R and E focus on data use for action. Review (R) examines regular analytical reviews of health sector progress and performance, together with national analytical capacity. Enable (E) looks at the policy, governance, and digital foundations needed to support effective data use.The Western Pacific Region shows relatively strong performance in the Review (R) and Count (C) interventions. Most countries in the Region demonstrate good analytical reporting and institutional capacity for analysis and learning. More than two-thirds of countries show more mature CRVS systems, driven by improvements in birth and death registration. However, medical certification of cause-of-death remains a key gap, with limited or low coverage in over half of countries in the Region.Performance under the Survey (S) intervention is mixed. While surveillance systems are generally strong, several countries in the Region continue to face challenges in implementing their surveys and censuses. Monitoring health-related SDGs is still a challenge for more than a third of countries in the Region.The greatest challenges are observed in the Optimize (O) and Enable (E) interventions. More than half of countries have lower maturity levels in routine health service and resource systems. Two-thirds of countries also face challenges with effective use of data and evidence for policy and action, largely due to gaps in digital infrastructure, governance and legislation for health data systems, and especially in data and sharing. &amp;amp;amp;amp;amp;nbsp;As part of the SCORE methodology, multi-stakeholder consultations and validation workshops were conducted in many countries to review findings and plan strategies for HIS strengthening. The HID unit continues to provide targeted support to facilitate dialogue and assist countries in developing HIS improvement plans. These plans guide governments and partners to align investments and coordinate efforts for maximum impact.WHO also assists countries with tailored technical support to address key gaps as requested by countries/national health authorities. SCORE assessments should be conducted periodically to monitor progress in HIS strengthening, although progress across addressing gaps identified in SCORE should be continually tracked as countries implement improvements.Additional countries will be supported to implement SCORE in 2026. The Regional Vision delivery-for-impact target, endorsed by Member States, is for all countries and areas to have implemented SCORE assessments and have an increased SCORE index by 2029 while WHO is aiming for 80% of Member States in the Region to conduct round two assessments. Countries yet to complete assessments are therefore encouraged to contact the HID unit at the WHO Regional Office for the Western Pacific for tailored support.The implementation of SCORE HIS assessments in the Western Pacific Region was supported by The Gates Family Foundation.
Scientists create robots smaller than a grain of salt that can think
Researchers have created microscopic robots so small they’re barely visible, yet smart enough to sense, decide, and move completely on their own. Powered by light and equipped with tiny computers, the robots swim by manipulating electric fields rather than using moving parts. They can detect temperature changes, follow programmed paths, and even work together in groups. The breakthrough marks the first truly autonomous robots at this microscopic scale.
🎧'Absolutely incredible' - a look back on title number 20
A new hour-long special from BBC Radio Merseyside, titled 'Now, that's what we call number 20', is available to listen to and download on BBC Sounds. The programme looks back on Liverpool's record-breaking 2024-25 title-winning season, where the Reds stormed to their 20th league title in Arne Slot's first year in charge. Paul Salt and Carl Woodward reflect and offer their analysis, before the story of the campaign is told through commentary, interviews and and other soundbites from BBC Radio Merseyside's Total Sport.
Saïd Business School, University of Oxford, partners with global digital skills platform Simplilearn to launch five AI-focused professional programmes for business leaders
Simplilearn, which has more than eight million learners in 150+ countries, has agreed a strategic partnership with Saïd Business School, University of Oxford, to deliver five cutting-edge programmes to professionals worldwide. Focused on AI-driven business and technology education, the programmes bring together the academic excellence of Oxford Saïd, as part of the world's #1-ranked university (Times Higher Education World University Rankings), with Simplilearn's international platform.
German business welcomes pending return of UK to Erasmus Programme
German business has welcomed the United Kingdom's re-entry into the European Union's Erasmus youth education programme from 2027 and hopes that it will lead to an easing of visa requirements. Ulrich Hoppe, head of the German-British Chamber of Commerce (AHK) described the decision as "a very significant step" in remarks made to dpa days after Brussels and London agreed on the step.
WHO highlights health risks and opportunities in the global waste crisis
A new World Health Organization (WHO) report, Throwing away our health: the impacts of solid waste on human health – evidence, knowledge gaps and health sector responses, warns that poorly managed solid waste is driving a public health crisis and calls for urgent action to protect people and the environments they live in.Globally, the volume of municipal solid waste is growing at an unprecedented rate. Yet, many countries still lack the systems and resources to manage this waste safely. “Solid waste reflects how our societies produce and consume, and how we treat people and the environment in the process,” said Dr Ruediger Krech, Director a.i., Department of Environment, Climate Change, One Health & Migration at the World Health Organization. “If we continue to treat waste as an afterthought, we will lock in avoidable disease, climate pollution and deep social inequities. This report is a clear call to put health and equity at the centre of how we design, manage and ultimately reduce waste.”The report summarizes evidence on how solid waste – especially municipal solid waste – affects health through polluted air, water, soil and food. When waste is not collected, or is dumped, burned or not poorly treated, it can release hazardous chemicals, contaminate drinking-water sources and create breeding grounds for insects and rodents.Communities underserved by waste management services, those living near dumpsites and poorly managed landfills and incinerators, children and pregnant women, as well as waste workers – particularly those working informally – face the greatest risks. For the water, sanitation and hygiene (WASH) community, the report underlines that safe management of municipal and health care waste is integral to safely managed, climate-resilient systems.A large share of municipal solid waste is still not collected or is disposed of in uncontrolled conditions, including open dumpsites and open burning. These practices damage ecosystems, contribute to climate change and undermine efforts to build healthy cities. When waste is properly managed, however, it can become a resource – generating energy and creating green jobs. The report calls for a coordinated, multisectoral response grounded in the waste hierarchy: preventing waste where possible, then reducing, reusing and recycling, with safe recovery and disposal.Key actions for governments and partners include reducing waste generation at source; expanding affordable and reliable waste collection services, especially in underserved communities; improving control at recovery and disposal facilities; and eliminating open dumping and burning, including hazardous waste. The new report identifies a central role for the health sector in addressing solid waste as a public health threat. The health sector can prevent and minimize health-care waste at source, improve segregation and safe treatment, invest in cleaner climate-resilient technologies, and advocate for health-protective policies and standards. The report also encourages more surveillance, research and biomonitoring to strengthen the evidence base, and promotes social protection and inclusion of informal waste workers.“This report gives countries and health authorities a very practical agenda,” said Mr Bruce Gordon, Head, Water, Sanitation, Hygiene and Health Unit, WHO. “Health ministries can start now by ensuring safe management of health-care waste, developing strong occupational health programmes for waste workers, and working with municipalities to reduce health risks from solid waste by closing open dumps and burn sites and gradually improving towards safe services. These concrete steps save lives today and will make cities cleaner and healthier in the future.