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Brain fog and the FemTech market | Investors Lab

A slew of pharma heavyweights (Eli Lilly, Bayer, Pfizer, Merck, Viatris, Novo Nordisk, Roche and AbbVie) have a piece of the pie in estrogen replacement.

Oct 21 • 8:30 AM EDT • Science • sciencenews.org

BNSF recognized with Patriots in Business award

Progressive Railroading Daily News

Oct 21 • 8:00 AM EDT • Business • progressiverailroading.com

The Politics of Tit-for-Tat

Oct 21 • 7:25 AM EDT • Politics • execfunctions.org

Marshall faces final debate in fight for political life

In today’s issue: Marshall, Hamilton meeting in final debate Trump unveils fraud whistleblower program Big midterm spending in final weeks Backlash to controversial Ramaswamy ad Sen. Roge…

Oct 21 • 7:08 AM EDT • Politics • thehill.com

Rochester colleges expand mental health workforce training amid shortages

Rochester colleges like Nazareth and St. John Fisher expand mental health training programs to address workforce shortages and improve community access.

Oct 21 • 7:00 AM EDT • Health • rbj.net

NDSCS Science of Leadership program helps students build leadership skills

Students receive $4,000 scholarships and gain experience through mentoring, interactive sessions and community service.

Oct 21 • 7:00 AM EDT • Science • wahpetondailynews.com

How Alzheimer’s and dementia patients teach Wisconsin’s next generation of health care workers

Through the New Friends program, students get experience connecting with people living with cognitive changes, and mentors get social connection during a particularly lonely time.

Oct 21 • 7:00 AM EDT • Health • wisconsinwatch.org

Iowa basketball receiving votes in preseason AP Top 25 Poll

After a memorable trip to the Elite Eight last spring, Iowa basketball is among a list of programs receiving votes in the preseason AP Top 25 poll.

Oct 21 • 6:45 AM EDT • Sports • sports.yahoo.com

Nancy Pelosi isn't sitting out the fight to replace her

The San Francisco lawmaker has dived into the intraparty fight to succeed her in Congress. Is it personal, or her prerogative to have a say in her replacement?

Oct 21 • 6:00 AM EDT • Politics • latimes.com

Miami-Dade Small Business Program: New opportunities

Getting your Trinity Audio player ready... For a small business owner, winning a government contract can be a significant milestone — obtaining steady revenue, scaling up your business, and achieving long-term growth. In Miami-Dade County, an important first step for many businesses is becoming certified through the county’s Small Business Development programs. Today, Miami-Dade County […]

Oct 21 • 5:35 AM EDT • Business • communitynewspapers.com

Rural Health Transformation implementation begins; Here’s what the money will do

Gov. Patrick Morrisey announced the first allocations of the Rural Health Transformation Program Awards, totaling nearly $2.4 million, on Sept. 4, 2026, to fund worksite clinics and employer-based healthcare services across West Virginia.

Oct 21 • 5:30 AM EDT • Health • wvgazettemail.com

Illini Bluffs star commits to Missouri Valley Conference volleyball program

Illini Bluffs junior Emerson Eeten helped her team to a Class 1A regional title match as a sophomore. Now, she's headed to the Missouri Valley Conference.

Oct 21 • 4:04 AM EDT • Sports • sports.yahoo.com

Hurricanes 6, Canucks 3

Nikolaj Ehlers, Logan Stankoven, and Nicolas Deslauriers each had two goals to lead the Carolina Hurricanes to a 6-3 win over the Vancouver Canucks at Rogers Arena on Tuesday night. The win gives Carolina eight wins in their last nine games and they also have a 2-1-0 record during this road trip. Deslauriers scored the […]

Oct 21 • 1:45 AM EDT • Sports • sports.yahoo.com

25% Of Middle Schoolers Proficient In ELA, Science; 18% In Math

According to a recent presentation by district leaders, who described those numbers as “steady progress” and a small improvement from previous years.

Oct 20 • 8:50 PM EDT • Science • newhavenindependent.org

Scientists Just Discovered That Earth’s Core Is Leaking, and It Has Been for Billions of Years

A new study suggests ancient hydrogen trapped deep inside Earth has been slowly escaping into the mantle for billions of years.

Oct 20 • 8:08 PM EDT • Science • vice.com

SpaceX’s Musk Lauds Its Soaring Cloud Business and Possible Tesla Merger

SpaceX put on a bit of a show for shareholders today—and I’m not referring to the sizzle reel of rocket and space videos it showed on its earnings call. No, the big attention grabber was the update from CEO Elon Musk on the progress of SpaceX’s contemplated merger with Tesla and just how ...

Oct 20 • 8:01 PM EDT • Business • theinformation.com

Area school business managers recognized

BISMARCK – The North Dakota School Boards Association (NDSBA) recognized Velva School District Business Manager Skyler Helseth and Powers Lake School District Business Manager Shayna Johnson as graduates of the North Dakota School Business Managers Certification Program (NDSBMCP) during its annual convention on Oct. 8 in Bismarck. The certification program offers 20 college level courses […]

Oct 20 • 8:00 PM EDT • Business • minotdailynews.com

New Richland Lab Could Transform How Scientists Study Microbes and Boost Regional Jobs

The BriefGroundbreaking held Tuesday: PNNL officially began construction on the M2PC lab, a 30,800-square-foot facility funded by the U.S. Department of Energy's Office of Science that will study soil microbes to improve crop productivity and develop new biotechnology applications. The facility will be open to researchers from around the nation and the world.Research timelines could shrink dramatically: The facility's automation and AI capabilities could reduce experiments that currently take six months to just 72 hours, allowing scientists to explore more possibilities faster than ever before.New jobs coming to the Tri-Cities: The project is expected to create positions for automation engineers, AI experts, roboticists, technicians, and skilled craftspeople, with the facility opening in 2029.RICHLAND, Wash. — Pacific Northwest National Laboratory broke ground Tuesday on a first-of-its-kind facility that could accelerate scientific discoveries about the microscopic organisms living in soil—organisms that may hold the key to growing more food and developing new energy technologies.The Microbial Molecular Phenotyping Capability, or M2PC, represents a significant investment in automation and artificial intelligence to speed up research that traditionally takes years to complete. The 30,800-square-foot facility will house more than 100 connected automated instruments designed to study microbes at a pace and scale never before possible.Reshaping Agriculture's FutureThe M2PC facility will not put a new tool directly into a farmer's hands tomorrow morning, but it is actively reshaping the commercial pipeline to solve agriculture's biggest headache with biologicals: inconsistent field performance. For years, PNNL researchers have explored how microbes work and how they might help produce useful materials, advance energy technologies, and address challenges involving critical materials and minerals. But those experiments have been limited by what researchers could accomplish by hand."They can be used to provide nutrients to a plant so that the plant would grow more. So, like increasing your crop productivity, for example," said Douglas Mans, PNNL's Associate Laboratory Director for Integrated Discovery Sciences.PNNL's own research shows soil microbes can help plants access nutrients and withstand drought—benefits that could prove crucial as farmers face growing environmental pressures. The M2PC facility will allow scientists to identify and optimize useful microbes faster than ever before, accelerating the development of biological solutions that actually work consistently in the field.What Makes M2PC UniqueThe Microbial Molecular Phenotyping Capability differs from traditional research labs because it operates as a first-of-its-kind, AI-enabled autonomous laboratory designed to shrink experimental timelines from years down to months or weeks. The M2PC lab will connect more than 100 automated instruments to grow microbes, prepare samples, measure their behavior, and link observations to the molecular processes behind them. Artificial intelligence will help analyze results and guide the next experiments, allowing scientists to explore more questions faster.Deb Gracio, PNNL Director, emphasized the transformative potential during Tuesday's groundbreaking ceremony: "Research that has taken years will become possible in months and hopefully in weeks."That acceleration is already being demonstrated. PNNL's smaller automated lab, called the Anaerobic Microbial Phenotyping Platform or AMP2, completed three experimental cycles in just 72 hours—a process that normally would have taken about six months."That normally would have taken us about six months … and we were able to do that in 72 hours," Mans said.The AMP2 laboratory is not being closed or replaced. Instead, the current 1,800-square-foot laboratory serves as an active prototype and precursor for the much larger M2PC facility. AMP2 will continue operating as a separate lab designed to run anaerobic experiments—those conducted in the absence of oxygen—while M2PC will focus on aerobic research.Broader Applications Beyond AgricultureWhile improving crop productivity is one important application, the M2PC facility is designed to support research into multiple areas critical to national priorities. The lab will advance research into biofuels, manufacturing materials, and energy technologies. It will also help researchers understand how microbes respond to environmental changes and how to design biological systems for biotechnology applications.As a flagship component of the Department of Energy's Genesis Mission, M2PC represents a significant investment in using artificial intelligence and automation to accelerate U.S. scientific discovery. Dorothy Koch, Associate Director of the DOE Office of Science Biological and Environmental Research program, highlighted the facility's importance during the groundbreaking."M2PC will accelerate biological discovery and design," Koch said, noting that the facility is expected to conduct a minimum of 500 strain experiments per week, 100 microbiome experiments per week, and take a million measurements per month.Economic Opportunity for the RegionBeyond the scientific breakthroughs, the M2PC project represents significant economic opportunity for the Tri-Cities region. The facility will require hiring automation engineers, AI experts, technicians skilled in operating robotics, and specialized craftspeople to build and maintain the sophisticated equipment."We're anticipating that type of hiring," Mans said when asked about job creation.PNNL has already begun recruiting talent nationally and internationally for positions related to the smaller AMP2 lab, bringing automation engineers from cities like Boston and San Francisco to work in the region. The M2PC facility is expected to accelerate that trend."This capability won't really exist anywhere else in the world," Mans said, suggesting the facility could become a draw for scientific talent seeking to work on cutting-edge biotechnology research.Timeline and Next StepsThe M2PC facility is expected to open in 2029. Between now and then, construction crews will level and prepare the ground, while the building takes shape. Simultaneously, Ginkgo Bio Works, the automation contractor, will build the facility's automation components off-site so they can be installed as the building is completed.In the interim, PNNL researchers and the broader scientific community will begin planning the first experiments to be conducted in the facility, ensuring research is lined up and ready to begin as soon as the doors open.The groundbreaking ceremony included representatives from the Department of Energy, PNNL leadership, and elected officials at the federal, state, and local levels, underscoring the project's significance to the region and the nation's biotechnology future. News The U.S. Department of Energy Secretary tours Pacific Northwest National Laboratory Dan Hanson, Apple Valley News Now News Beyond DNA: Scientists Explore New Frontiers in Biology Research Dan Hanson, Apple Valley News Now News TRIDEC optimistic that Hanford, PNNL will see funding in national budget Robert Desaulniers News Big picture science: monitoring the Yakima River Basin News PNNL research could shape the future of fighting fentanyl ​COPYRIGHT 2026 BY APPLE VALLEY NEWS NOW. ALL RIGHTS RESERVED. THIS MATERIAL MAY NOT BE PUBLISHED, BROADCAST, REWRITTEN OR REDISTRIBUTED.

Oct 20 • 7:44 PM EDT • Science • applevalleynewsnow.com

Brewers President of Business Operations sides with Timeless Ticket holders: 'We did not live up to the spirit of the program'

Oct 20 • 7:21 PM EDT • Business • sports.yahoo.com

Michigan Senate Candidates Make Dueling Pitches to Business Leaders in Detroit

Mike Rogers and Dr. Abdul El-Sayed, the candidates in the tight race, defended their economic policies at the Detroit Economic Club.

Oct 20 • 5:40 PM EDT • Business • nytimes.com

WATCH LIVE: Illinois U.S. Senate candidates face off in forum to replace Durbin

Oct 20 • 5:37 PM EDT • Politics • pbs.org

ECU Health launches Centering Pregnancy group prenatal care program for moms-to-be

Oct 20 • 5:35 PM EDT • Health • wcti12.com

Rioting in France gives Trump a new talking point as he tries to stave off GOP midterm losses

As Kansans were waiting for President Donald Trump to arrive at his rally in Wichita this week, they were treated to a new addition to the pre-show program: footage of this weekend’s violent protests in France, most of it clipped from Fox News, aired on large screens.

Oct 20 • 5:25 PM EDT • Politics • cnn.com

DDA Launches Downtown Business Banner Program

DDA Launches Downtown Business Banner Program The Trenton Downtown Development Authority is giving local businesses a new opportunity to put their name on display in downtown Trenton. The DDA’s Downtown Banner Program will allow businesses to have their name displayed on a downtown banner for […]

Oct 20 • 5:23 PM EDT • Business • discoverdade.com

When I was 8 years old, Carl Sagan showed me the universe I want you to see

I have always tried to pattern my interactions with my program audiences like Carl might have done. Every chance I get to do that is one more opportunity I have to spark someone else’s interest in science.

Oct 20 • 4:36 PM EDT • Science • adlerplanetarium.org

Feds hold back an additional $1.2 billion in California Medicaid reimbursements

In May, the administration held back $1.3 billion in Medicaid reimbursements to California over concerns about "fraudsters" in the state's hospice and in-home care programs.

Oct 20 • 4:33 PM EDT • Politics • latimes.com

Political science, history student connects hometown roots to DC policy work

Dawson Glogau gained hands-on experience in policy research and advocacy during a summer internship in Washington, D.C., through the Liberal Arts Semester in Washington Program.

Oct 20 • 4:24 PM EDT • Science • psu.edu

Political science, history student connects hometown roots to DC policy work

Dawson Glogau gained hands-on experience in policy research and advocacy during a summer internship in Washington, D.C., through the Liberal Arts Semester in Washington Program.

Oct 20 • 4:24 PM EDT • Politics • psu.edu

Kaiser Permanente Hawaiʻi invites Maui students to explore health care careers

Kaiser Permanente Hawaiʻi is helping inspire the next generation of health care professionals through its upcoming Career Exploration Day on Saturday, Nov. 14, in partnership with Maui Economic Development Board’s STEMworks program.

Oct 20 • 4:00 PM EDT • Health • mauinow.com

University of Maryland expands key reproductive health program

The school is using more than $16 million in state grant funds over five years to build on previous work that already trained more than 100 clinicians, students and other health professionals in abortion care.

Oct 20 • 3:50 PM EDT • Health • wypr.org

Renovated Brook Farmhouse now home to Mohonk Preserve’s science programs

A natural history...

Oct 20 • 3:16 PM EDT • Science • hudsonvalleyone.com

Medicare paying billions in Utah health care, new study shows

Medicare is spending $6 billion on Utahns yearly as enrollment in the health insurance program inches closer to 500,000. That’s the most any federal health care program is spending on the Bee…

Oct 20 • 3:12 PM EDT • Health • abc4.com

The Metro: Donavan McKinney hopes to inject more humanity in politics

Democratic party member and progressive Donavan McKinney sits down with The Metro to discuss what he'll deliver if elected to the House.

Oct 20 • 3:05 PM EDT • Politics • wdet.org

Sundar Pichai: Google’s Frontier Imperative, Compute Scarcity Dilemmas, Future AI Products and Businesses

Alphabet CEO Sundar Pichai has little patience for doubts about Google’s willingness or capacity to compete at the frontier of AI. His company’s latest Gemini 4 Argon model — long-promised and recently delivered — beats OpenAI and Anthropic’s latest public models on coding, math, science, and knowledge-work benchmarks and has placed Google’s AI back among the world’s best. Amid chatter that Google was fine with good-enough lightweight ‘Flash’ models, Pichai pushed back hard against any suggestion that company is limiting its research ambitions. “We won’t do it any other way,” he told me in a Big Technology Podcast interview recorded this week at Google’s Mountain View headquarters. Pursuing cutting-edge research is costly for Google, requiring compute and chips that otherwise could be sold at a high markup by its cloud business. But Pichai said allocating resources to frontier AI development is “ground zero” for Google. “Our cloud business is at any given moment in time forgoing short-term revenues because we are making compute trade-offs to support frontier AI development,” Pichai told me. In our conversation, we discussed Argon (which Pichai says processed three times as many tokens as Gemini 3 in the 72 hours after launch), AI’s role in developing better models, the AI interface of the future, competition with OpenAI, Google’s partnerships with Anthropic and Apple, data centers in space, and the nature of his optimism. You can read the full conversation, lightly edited for length and clarity, below, or listen to it on Apple Podcasts, Spotify, YouTube, or your podcast app of choice. Alex Kantrowitz: Google is back at the frontier with Gemini 4 Argon, which beats OpenAI’s and Anthropic’s public models on benchmarks spanning coding, math, science, and knowledge work. The conventional wisdom was that Google had given up on the frontier to focus on fast, good-enough models for its products. That was wrong? Sundar Pichai: Very wrong. Look, we are so committed to being at the frontier. It’s in our DNA. We won’t do it any other way. We’ve been thinking about the AI frontier for well over a decade now. The frontier is very dynamic. It’s very competitive. It’s very exciting. I couldn’t be more pleased with how Argon has come together. We took our time with it. We made sure we tested it safely and deployed it carefully. We took a bit longer than our other models, given its capabilities. Across the board, be it for agentic work, knowledge work, coding, creative tasks, Argon is one of the really good frontier models. The first 72 hours since we launched, it’s almost up to 25 trillion tokens used, which is about three times what Gemini 3.0 had in the first 72 hours. And we are capacity constrained as we are serving it. Excited, but there are always areas….. You know, the frontier is very dynamic, and you have to keep evolving the models. There are areas which we can see we need to improve as well. We’ll be at work on all of that as well. Which areas? On any given model, Argon would be across the board better at everything if you just look even two months back. But the space is so evolving. Even on coding, for example, there are pockets where we know we need to do better, and there’s clear feedback. We’ll make it better. The argument for standard models is that they’re already good enough to build great products, with the frontier valuable only for certain tasks. Meta built Muse with good models rather than the best, and Google could put standard models into Maps, Gmail, and Search. Why isn’t that sufficient? It’s definitely not how I have thought about it at all. We are deeply committed to driving the state of the art and actually pushing where this technology can go, all the way from transformers. That’s a journey we’ve been on. You will see us continue to do that. When you’re at the frontier, you get an earlier look into the emerging capabilities, earlier than others, which helps you better prepare for the future. We are fortunate to have a wide set of opportunities across consumer and enterprise. Some of our cloud customers, for sure, want the model at the frontier. The frontier models will be better at developing the next set of models in an era of recursive self-improvement. I would argue it matters there. Internally, we have definitely seen a steep point of inflection by deploying Argon to our developers. It definitely tackles problems which our previous models could not do. Being at the frontier puts you at the innovation frontier and helps you drive that as well. There is room for models of all sizes and capabilities. That’s why we did Flash, Flash-Lite, etc. I agree with you that you can develop very good product experiences with not necessarily the most frontier model, because they tend to be slower and more expensive too. But we care about the Pareto frontier, and we’re committed to doing all of that. You said developing frontier models gives you a look at what’s coming. What do you see on the horizon? What makes this moment so exciting is you build something which you think is a culmination of months of work, and you put it out. You already see clear headroom ahead. We’ve all been working on these agentic, long-horizon capabilities, but clearly the frontier is going to have multiple of these agents working together to do things. That’s an example of an exciting paradigm underway. It’s also clear to me that users, both in consumer and enterprise, will have access to some multi-agent framework for them, working all the time doing things. It feels like a moment of infinite possibilities. Sergey Brin said one of Argon’s core innovations was relying more on the model to help develop the model. Yet incidents involving OpenAI’s bots breaking containment and Google’s bots accessing a site they shouldn’t have suggest these systems still aren’t perfectly aligned. Isn’t there reasonable cause for concern about accelerating toward recursive self-improvement? There are three parts to your question. Let’s first talk about RSI itself. You’re right, Sergey mentioned RSI being a critical contributor as we are developing Argon. But to be very clear, today, in a continuum, we are pretty far from the end state of RSI or something like that. The right way to describe it is you have RSI loops along with AI researchers in various aspects of model development. You almost have agents helping AI researchers in some automated way work together to build these models. It’s good to at least understand where we are today, and it’s super exciting. I expect that continuum to keep making progress as we go into next year. The second question is around safety. Security comes from defense in depth. You’re talking about alignment, obviously. We all are doing a lot of work to make sure the models are as aligned as possible. But it’s an active area of research, and there are clear gaps. That’s not the only thing we rely on. You have the work you do on alignment, but beyond that, we put a lot of effort into real-time monitoring as these models are working. Making sure you have good telemetry into what’s happening so that you can intervene in real time if you see unexpected behaviors. How you do that, the architecture with which you do that, how you make sure it’s all sandboxed and isolated in a way that it can continue doing its job during real-time monitoring — these are all areas of investment. Obviously, when we deploy these models, giving customers, enterprises, control, both with real-time monitoring, but their ability to decide where they deploy, what type of data which models ever have access to, etc. All that work is very, very important, and we are doing a lot of that. As an industry, we need to constantly up our game and take the time to do all this stuff, including dedicating the compute required to make sure you can safely deploy these models. The third part is: Is it all enough? This is why there are a lot of conversations in the industry, and I think it’s reasonable to be worried. The right way to approach something you worry about is early on thinking about what more we can do. As an industry, you’re definitely seeing increased levels of work on alignment, testing for safety, etc., as we deploy these models. The next step would be developing better standards so there are cross-industry standards of how we do these things, including the ability to evaluate using independent evaluators. If you look at areas like financial controls, we have accounting standards, we have independent auditors. Those are all the next natural steps for us as an industry to work toward, and regulation will end up playing a role as we go through all of that as well. Google pursues both language models and world models, while some other AI companies like OpenAI have focused more heavily on LLMs as the path to AGI. Why is world-model research important to you? As humans, you obviously perceive the world around you, and you’re taking all those inputs. Making sure these models are able to understand the laws of physics, simulate the world in high fidelity. All that, I think, are key enabling blocks for intelligence. We are working across all possible applications of this. Take an area like robotics. It’s not an accident: If you look at embodied reasoning benchmarks, Argon is state of the art. That all comes from our experience building world models. Inherently, I would expect there will be architectures which will converge all of this in the future. But for us, we view this as, today, this jagged frontier that is intelligence. We want to be at the frontier of all the possible approaches, and that will help us both drive better research, better insights, and develop a much better AGI model, is how we think about it. Some people argue Google should focus on selling its computing resources rather than using them for AI research. Cloud wants to sell compute at a high markup, while researchers need a very big computer to build the best models. How do you balance those demands? Ground zero for us is making sure we are investing in the compute that’s needed to be at the AI frontier. In 2015, I set the company to be AI-first. AI is that key horizontal ingredient across everything we do, all the way from Search to Cloud to Waymo. That is ground zero for us, making sure both for research and developing the models that we have enough compute needed. Beyond that, we have these independent businesses which each have their own long-range plans. They’re using those long-range plans to project forward, and we plan for compute for all of them. The cloud team, they have a business and they have a projection and they have demand signals. They have committed contracts. With that help, we can plan on a long-term compute trajectory for them. We’re fortunate to have this wide set of opportunities. There’s no company in the world which isn’t making trade-offs at any given moment in time. But the first principles we operate on is making sure we have enough compute to invest in the frontier, and that’s non-negotiable, and everything else works on top. Remember, we are building our own compute, our own data centers. There are long lead times. The compute we have today is a function of decisions I made in 2024. Even if you think back to a year from today, last year the agentic coding takeoff hadn’t happened. Today, obviously, when you sit and look at anything, everyone is short—not just us, other companies—and everyone wishes you had two times what you had planned for. That comes with the territory. At any given moment in time, we are planning for what we would need two to three years out in the future. You’re going to find some decisions you make may look suboptimal two years out, depending on where the state of the art is. I don’t spend too much time thinking about it. The way I think about compute allocation is making sure Google DeepMind, both for research and frontier model development, is cutting edge in terms of compute access. After that, we plan for all our businesses. It’s great we can provide our compute to other people too, like we have done. It allows us to scale that up, get real tests for it in the widest application set possible, test it in the real world, and make sure we are at the cutting edge of technology at every layer of our AI stack as well. Ben Horowitz relayed on a podcast that Andy Jassy had said compute was sold out until 2028. Are you seeing the same thing? If today a customer is coming out and asking us for compute in ’27, that is incredibly difficult to do. Even last year we went out and leased some short-term compute to accommodate some customers and help them out. But yes, we are all dealing with similar timelines. Every major technology shift seems to involve overbuilding, from railroads to fiber. Do you think that’s happening here? It depends on the time frames you’re looking at. This level of build, if I take a long enough time frame, it makes complete sense to me. We are at early stages of the most consequential technology ever, and this is not like fiber. It’s not dark. We are using it. We are capacity constrained on a daily basis. The applications, the underlying technology is improving rapidly. But running a company, the way I work through the moment is you look at your demand signals. You look at your committed revenue opportunities that you’re getting in the form of contracts. You balance that with the underlying technical capability, or internally you balance how we are using it internally, the model trajectories. Based on all that, you take a disciplined approach—a confident, aggressive, but disciplined approach—to plan out compute. But when you talk about the broader economy as a whole, you’re having people operate with various levels of risk. I focus on what I can control as a company and plan through it. If your question is, can there be an overbuild? Yes, because you can have some constrained components. Remember, what matters is a set of everything you need to build out that compute. Memory, electricity, electricians…. Land. Like 2,000 components or more. You could get constrained at some point. There could be things which cause bottlenecks, and then you could have overbuilds. There could be external shocks to the economy. There are macro risks. All that is possible at any given time. But am I confident that the compute we are planning for, we will have uses for it given enough time? Absolutely, yes. I was in the room when you said AI would be as profound as fire and electricity. If you believe that, shouldn’t you give researchers the biggest possible computer, even at the expense of today’s cloud profits? We’re all doing some form of that. Our cloud business is at any given moment in time forgoing short-term revenues because we are making compute trade-offs to support frontier AI development. What you’re seeing is true already. But you want to be thoughtful. Even our AI researchers have some constraints, which are also good. That’s what inspires creativity. That’s what helps you come up with a more efficient algorithmic breakthrough, maybe to use less memory. What we are committed to is to invest what’s needed to stay at the frontier. OpenAI President Greg Brockman told me a few months ago that the ideal AI product might have no interface at all—just as natural as conversation. What do you think the interface looks like in the age of AI? Computing historically has been humans adapting to computing. With AI, it’ll be the other way around. The technology will adapt seamlessly to how humans live and go about their day-to-day life. You want to be able to speak to that AI when you want to. It has context. It can be persistently running somewhere, give you continuity. You’re not dealing with a lot of complexity. It’s natural. All that makes sense to me. That doesn’t mean it won’t have any interface, however. Nowadays, even on my phone, Gemini voice models are so good. I can just press the microphone button. I can just ramble. That’s why we call it Rambler. I can ramble. It intelligently corrects with my personal context. Even my friends’ names, weird names, it gets it right, even if it first guesses it wrong. It’s amazing. I’m not going in, backspacing, editing once I finish saying it. It’s remarkable how good it’s gotten. But there are going to be moments you will need an interface. You may want to entertain yourself. You may want to watch a video. You may ask your AI to create something, and you want to watch it, consume it. The way I think about it is, you want it to be as seamless and as natural as possible, and that you are not doing the hard work adapting to whatever the interface is. The technology is adapting to how you’re working at any given moment in time. When I asked Sam Altman about competition from Google, he argued that OpenAI was building AI-native products and implied Google was bolting AI onto existing ones. Do you accept that framing, and can a “bolt-on” compete with an AI-native product? First of all, it’s a very dynamic moment. We are all pushing each other. OpenAI has pushed us as a company too. This is not just we are doing something to them. Far from it. Yes, Google went into its own version of a code red too. In the AI moment, all of us have to respond with varying levels of urgency at any given moment in time. We are constantly building new products as well. Gemini was built from the ground up as a product—the Gemini app I’m talking about. Or tomorrow, as all of us are adapting to agents, are you bolting agents onto ChatGPT, or are they building it natively? How would you think about that? You can always put these questions back. I don’t think of it that way. I think of it as you want to build world-class product experiences that are AI-native and they are winning. Some of it is adapting products, some of it is rethinking new experiences. They will all be part of how you approach this moment. How do you expect to make money from these AI interfaces? If an agent recommends a product and I buy it, should it take a cut of the sale, even if that’s disclosed? I’m going to put enterprise aside. Consumers are going to increasingly value this technology. Take software developers today. Developers are willing to pay for these coding models because it really helps make them more productive. Nobody would want to code the way they were coding three years ago, or even the same time last year. When you’re delivering value, there’s value to be had. I’ve never seen examples where consumer products really scale to billions of users, where people are using it intensely, and haven’t had monetization to go along with it. If you’re providing value to people, there is inherent value to be had. The nature of it may change. You’re asking a scenario in which agents are doing stuff for you. At the end of the day, you will have commercial needs. The agents need to fulfill those commercial needs. The providers on the other side are going to see value in that. There’s going to be some mechanism by which it gets fleshed out. That’s what an efficient system does. But what matters is that you’re building those world-class consumer experiences. I promised myself one product feature request: Can you make Gemini-powered search in Gmail as good as searching Gmail through ChatGPT? What’s going on here? One of the exciting things we announced recently is the unified Gemini agent for enterprise, and we’re bringing that to consumers. These are persistent agents which run 24/7 in the cloud. We’re spinning up a micro VM effectively for every query, and from the runtime, the harness, the model—it’s all a headless service. It’ll work everywhere, and it has your context with you. You can address this agent whether you’re in Workspace, in Search, in Gemini. Agents are going to drive this unification from a customer experience, which people are looking for. When you have a broad product portfolio and you’re moving forward fast, there are always areas where you’re moving forward faster than some other areas. That’s valid feedback. But we are putting a lot of time and effort into making sure, as we build out our agentic experience, that unification and that capability works well across all these services. People have asked where Google’s equivalent of Muse or Dots is. Do you anticipate creating a new product to compete with them? Our goal with Gemini is to be a personal, proactive, and powerful assistant. That’s what we are working toward. You saw us describe the early versions of it at Google I/O this year with Spark. Effectively, already, if you open the Gemini app as a Pro or an Ultra user, you see Chat and Task, and they start giving you that agentic experience. With Argon now, that capability is dramatically accelerated. What we announced recently in our enterprise event, we are bringing that to consumers as well. Soon in Gemini, you will be able to ask something, and it’s a continuum. You don’t need to think about whether you’re asking a chat or an agentic task. It’ll just automatically do the right thing, and it can work persistently in the background securely and get things done for you. Already, empirically, when I look at what’s coming into Gemini in our app, last year you would have tagged them and most of them would have been chats. But a steadily growing percentage is already agentic tasks in Gemini. Yes, we are going to bring personal agents to our consumers. It’ll work in the Gemini app. It’ll work in Google Search. It’ll work in Gmail. You can address it, call it, etc. We want to make sure we’re getting it right. It’ll be powered by Argon, and we are very excited to bring it to our users. Google has invested and committed tens of billions of dollars to Anthropic. What do you see in Dario Amodei that makes you want such a deep investment and partnership? Very early on, when we looked at the founding team of Anthropic, it was very clear to us this was a world-class team which was involved in some of the earliest GPT models. We were quickly able to assess that they would be at the frontier. We’ve always tried to identify and partner with companies which would be at the cutting edge of technology. We’ve done that with SpaceX. We’ve done that with Anthropic. That’s what we saw, and we had a chance to partner. Is your partnership with Apple to license Gemini for Siri expanding, contracting, or standing still? For both us and Apple, that partnership was about translating the capabilities of AI into better experiences for users. I thought Apple has done a phenomenal job of incorporating—they customize these models and build it into Siri—and it’s been great to see the reception. We are committed to doing more. You’re going to do more with them? There’s nothing specific to comment, but it’s a partnership. It’s working well. What have you learned so far about the feasibility of data centers in space? It’s a very exciting project. Projects like this remind me—I still recall that moment in the desert for the DARPA Grand Challenge, watching the Stanley car compete in it, which ended up being the basis for Waymo. With all these technologies, you’re at a moment in time where it looks a bit like sci-fi, but 10 to 20 years down the line, it’s actually working in a meaningful way. I feel the same in space. We’ve always believed in betting big on these technologies. Quantum has been a great example of it. We’re probably 10 years into the journey. Waymo, we are almost 20 years into the journey. Space, we are two to three years into the journey. It’s clear to me that it’s an approach which will make a lot of sense in the future. Being in sub-synchronous orbits with 24/7 access to the most abundant form of energy we have access to will make a lot of sense for this exponential increase in compute that we are going to need. Having said that, this is a challenging project. The team has disciplined milestones. It was a super exciting milestone to send the TPUs up to space. Sometime, as we are speaking, we are expecting a “hello world” moment from them. I look forward to seeing that happen, and we’ll continue investing here too. You previously said 25% of the code written within Google was written by AI. What’s the number today? That number in our world today is meaningless in the sense that every part of what we now touch is influenced by AI deeply. What we are tracking with Argon, for example, it’s been a point of inflection. People are using Argon to really go tackle complex projects, including projects which affect millions of lines of code. In the four weeks since we have launched Argon, we have seen a 30% increase in CLs, and more importantly, almost a similar increase—a one-third decrease in rollbacks. People are writing code more productively and better code with it. We are tracking it with newer metrics now. How are you dealing with opposition to data centers? If you can’t build in the U.S. the way you want to, where else do you go? We’re very committed to building our data centers very responsibly. When I look at our largest data centers in some of the communities where we have been the longest, I visit them, I talk to people. There are people who come and tell us their kids have gone to college because of our investments in these communities, and we’ve grown in those communities. To me, this is about doing it right. Engaging with the communities early, doing it transparently. We are committed to making sure we are bringing incremental power, and we cover 100% of the cost of our power needs for these projects. It’s understanding the impact on neighborhoods and making sure you’re working thoroughly to address them. Done rightly, you can continue making progress. But we are constantly taking feedback into account. I do worry not everyone operates the same way. People have been surprised by data centers showing up in their backyard. Those are all important. As an industry, we should continue to do better. But part of the reason, in a 20-year time frame, we are thinking about things like data centers in space is making sure we are able to put these data centers where maybe the trade-offs will be different. What unproven area of AI is Google working hardest to crack? Is it continual learning—getting models to keep updating after release—or something else? There are multiple parallel paths. You saw with Argon we have a million output tokens. With our Gemini models early on, we had a one-million context window on the input side. These are all examples of breakthroughs we are constantly working on. How do you think about synthetic data? How do you think about continual learning? How do you think about more efficient architectures? We do dedicate a meaningful percentage of our compute to these research bets too. It always goes hand in hand, including our world models. Those are all bets we are placing. Sometimes, as part of these bets, there are ideas that emerge which just make their way into the mainline models. Maybe we don’t fully talk about it, but we have multiple steps in these areas. Working in technology requires optimism that building something will improve the world, but those bets can leave real consequences when they fail. I recently returned to a town in El Salvador where enthusiasm for Bitcoin had given way to unfinished construction and something resembling a ghost town. How do you maintain the optimism you spoke about in your Stanford commencement address while accounting for those risks? I genuinely have a deep conviction that improving technology and improving access to technology makes people’s lives better. It’s been my personal experience in my life, out of which comes that deep conviction, optimism. But with that, I’ve always felt humanity’s journey is always about working hard to harness that technology to make it work well for society. The optimism is not an optimism that you just build whatever you want, whenever. You work hard to make sure you’re building technology in the service of humanity, to make the human condition better. That’s got to be the defining goal as we are approaching it. With that framework, I’m very, very optimistic. We are in very early stages of the kind of progress that we are going to see on many areas. We’re all talking about areas like healthcare. A lot of the progress is ahead. The ability to make things in a fundamentally cheaper way on many things where things have been getting expensive for a long, long time, discovering new materials, etc., which really bend the curve—it’s tough to step today and understand the impact of all that, but they’re going to be very profound. I’m very optimistic, but we have to be rightfully concerned about all the ways this technology can go wrong. Sundar, I know you don’t do many of these. Thank you. Thanks, Alex. Appreciate it.

Oct 20 • 1:47 PM EDT • Technology • bigtechnology.com

Local student wins photo contest with apropos shot

Heritage Days itself is a Rogersville tradition dating back to the late 1970s. Care NET’s photo contest for Hawkins County high school students is only in its third year, but

Oct 20 • 1:30 PM EDT • Entertainment • therogersvillereview.com

‘Healthy Rounds’: Supercharging the Immune System

Dr. Kapil Meleveedu, director of UConn Health’s Blood and Marrow Transplant and Cellular Therapy Program, joins Dr. Anthony Alessi’s podcast

Oct 20 • 1:15 PM EDT • Health • today.uconn.edu

Hackensack Meridian Health, Hunterdon Health to merge

Hackensack Meridian plans to invest $200 million into capital projects that support Hunterdon facilities and programs.

Oct 20 • 1:10 PM EDT • Health • modernhealthcare.com

Eight eMudhra CA Keys Compromised, Triggering Emergency Fixes Across Browsers and Software

Eight eMudhra CA keys were compromised, prompting browser blocks and software fixes. Chrome found no rogue certificates in CT logs.

Oct 20 • 1:09 PM EDT • Technology • thehackernews.com

Councilmember Mark Squilla is up for the PPA’s top job. Progressives are hoping to win his seat.

The potential of Squilla taking the job would shake up the race for his 1st District seat, and could give progressives an easier path to grow their ranks on Council.

Oct 20 • 12:57 PM EDT • Politics • inquirer.com

Michigan Medicine, UM Health-Sparrow expand precision oncology program

University of Michigan Health-Sparrow and Michigan Medicine are expanding the use of precision oncology in Lansing.

Oct 20 • 12:49 PM EDT • Health • wilx.com

Michigan Medicine, UM Health-Sparrow expand precision oncology program in Lansing

University of Michigan Health-Sparrow and Michigan Medicine are expanding the use of precision oncology in Lansing.

Oct 20 • 12:48 PM EDT • Health • fox19.com

Vernon County expands support for small businesses through grant program

15 Vernon County businesses have been awarded $10,000 each through the 2026 Elevate Vernon Grant Program.

Oct 20 • 12:39 PM EDT • Business • weau.com

Training solutions for your business

Director of Workforce Development and Continuing Education Programs Molly Salisbury joins Kerrigan to share how you can build your team's skills with training designed around your organization's needs.

Oct 20 • 12:35 PM EDT • Business • kctv5.com

NYC Health + Hospitals/Elmhurst and Queens Public Library Expand Partnership to Bring Health Education and Library Resources to Queens Residents

Elmhurst, NY – NYC Health + Hospitals/Elmhurst and Queens Public Library (QPL) today announced an expanded series of collaborative programs designed to

Oct 20 • 12:32 PM EDT • Health • nychealthandhospitals.org

Training solutions for your business

Director of Workforce Development and Continuing Education Programs Molly Salisbury joins Kerrigan to share how you can build your team's skills with training designed around your organization's needs.

Oct 20 • 12:27 PM EDT • Business • kctv5.com

Trump uses antisemitic slur to defend GOP Kansas senator

GOP Kansas Sen. Roger Marshall Marshall is locked in an unexpectedly tight reelection battle against Democrat Adam Hamilton in what might be the biggest surprise of the midterms.

Oct 20 • 12:14 PM EDT • Politics • seattletimes.com

AMD and Microsoft Bring FSR 4.1 to Xbox Series X|S, FSR Diamond Teased for Project Helix

AMD and Microsoft have confirmed that FSR Upscaling 4.1 is coming to the Xbox Series X and Series S. The news came in an AMD video presentation led by Jack Huynh, joined by Xbox CTO Scott Van Vliet and ASUS. The ROG Xbox Ally handhelds are getting it too, and it looks like they will be first in...

Oct 20 • 12:10 PM EDT • Technology • techpowerup.com

Chesapeake Bay Health Reaches 20-Year High, but Work Remains

The Chesapeake Bay earns its highest health grade in 20 years, restoration efforts progress but ongoing challenges remain. The Chesapeake Bay earned its

Oct 20 • 12:00 PM EDT • Health • conduitstreet.mdcounties.org

Scientists Built a Membrane That Breaks Down ‘Forever Chemicals’ Instead of Just Trapping Them

The membrane uses hydrogen and palladium to dismantle troublesome PFAS.

Oct 20 • 11:58 AM EDT • Science • zmescience.com

Intermountain Health Lutheran Breast Care Center Earns Re-accreditation

Intermountain Health Lutheran Hospital Breast Care Center in Wheat Ridge has been re-accredited under the American College of Surgeons (ACS) National Accreditation Program for Breast Centers (NAPBC).Breast cancer is the most common cancer diagnosed in women in the United States after skin cancers. Programs accredited by the NAPBC follow a model ...

Oct 20 • 11:49 AM EDT • Health • news.intermountainhealth.org

Negro Spirituals Royalty Initiative Is Launched

The Negro Spirituals Royalty Initiative (NSRI) is a new program, created by the Social Justice Matters team of South Congregational Church in Centerville and managed collaboratively with the Hyannis-based Arts

Oct 20 • 11:00 AM EDT • Entertainment • capenews.net

Scientists left in the dark by National Science Foundation grant application delays

The Major Research Instrumentation program offers grants of up to $4 million to scientists buying research equipment

Oct 20 • 10:45 AM EDT • Science • scientificamerican.com

NFL Mexico and CONADE Join Miami Dolphins Academy to Create Year-Round Flag Football and Education Programming Across the Country

The initiative, implemented through the Global Markets Program (GMP), reflects the commitment of the Miami Dolphins and their local partners in Mexico to promoting sports and bringing physical education to communities across the country.

Oct 20 • 10:42 AM EDT • Sports • miamidolphins.com

WSU professor Felix Lankester elected to National Academy of Medicine

Lankester’s pioneering work on vaccine delivery and community-based vaccination programs has helped transform rabies prevention and save lives in low-income countries.

Oct 20 • 9:00 AM EDT • Health • news.wsu.edu

'Office Space' star Richard Riehle dies at 78

Actor Richard Riehle arrives at the premiere of New Line Cinema's 'A Very Harold & Kumar 3D Christmas' at Grauman's Chinese Theatre on November 2, 2011 in Hollywood, California. (Jason Merritt/Getty Images)Richard Riehle, known for his role in the 1999 film Office Space, has died. He was 78.A statement shared by Artists & Representatives and Wright Entertainment, Inc. announced Riehle's passing on Monday, writing, "Our industry has lost an exceptional talent, and our community has lost a truly wonderful man.""We are deeply saddened to confirm the passing of our beloved client, Richard Riehle, this past weekend," the statement said. "A remarkable actor whose career in theater, film, and television spanned nearly five decades and more than 400 projects, Richard leaves behind an extraordinary legacy."The statement continued, "Beyond his immense talent, he will be remembered for his genuine goodness, boundless kindness, and unwavering generosity, particularly toward emerging actors and filmmakers, whom he encouraged and supported at every opportunity."Born on May 12, 1948, Riehle starred in many television series and films over the years.Notable projects include Casino, The Man from Earth and Deuce Bigalow: Male Gigolo.He got his start as an actor at the University of Notre Dame, where he was involved in the University Theatre and starred in several stage productions. He went on to earn a Master of Fine Arts in acting and directing from the University of Minnesota.While he's played characters that have an "average Joe" presence, he always made the most of his brief screen time.Some roles that he is remembered for include The Quartermaster in Glory, the train guard in The Fugitive, Reverend Scroggins in Fried Green Tomatoes and Bill Cozbi in Bridesmaids.On television, he starred as Principal Ed Rooney in the 1990 series Ferris Bueller and as grandfather Walt Finnerty in the early 2000s sitcom, Grounded For Life.In 2023, he also played Warden Reynolds in Barry.Riehle is survived by his wife, Jane Latham, and their four children.Copyright © 2026, ABC Audio. All rights reserved.

Oct 20 • 8:56 AM EDT • Entertainment • willmarradio.com

JMU Military Science program prepares future military leaders

JMU’s Army ROTC program combines rigorous training, hands-on leadership development, and strong alumni support to prepare cadets for success as future military officers.

Oct 20 • 8:55 AM EDT • Science • jmu.edu

How much longer will Sacramento’s progressive politics let Califia suffer?

“Cali is dying on the streets because there is no way...to help her.”

Oct 20 • 8:00 AM EDT • Politics • sacbee.com

'It makes me feel that we can do a lot about it': ESA official shares striking satellite snap of Europe's record-breaking summer heat waves

The head of ESA's Earth observation program tells Live Science why a striking image of a recent heat wave scorching Southern Europe gives her hope that we can properly monitor ‪— and eventually prevent ‪— similar extreme weather events in the future.

Oct 20 • 7:00 AM EDT • Science • livescience.com

San Marcos relaunches support program for local businesses

The city of San Marcos re-launched its SMTX BOOST program to provide local small businesses with free training, coaching and resources.

Oct 20 • 7:00 AM EDT • Business • communityimpact.com

A note to readers: Science, accountability and elections

Dear readers, As early voting begins, I wanted to share some news — and why it connects to the decisions we make at the ballot box. I’ve been selected for the inaugural cohort of the South Atlantic Climate Journalism Hub mentorship program, hosted by Covering Climate Now. I’m excited to join this group, learn from scientists and fellow journalists, and expand my science reporting. Science directly ties to governance. Local officials make decisions about where development goes, how infrastructure is maintained, what emergency preparations receive funding, and how communities rebuild after disasters. Understanding the evidence behind those decisions helps us evaluate whether our government is serving us well. Here in western North Carolina, those connections are all around us, in Lake Lure and beyond. Flood maps inform decisions about property and development. Engineering assessments help identify risks at dams and bridges. Rainfall forecasts guide emergency preparations. Geological information helps explain landslide hazards. Water testing gives communities information they need to assess conditions. Meteorologists’ knowledge and public perception of weather events shape public safety. Each involves scientific or technical knowledge. Each also raises questions about public responsibility: What did officials know? How did they use that information? What did they tell the public? What did taxpayers receive for their money? A study can identify a problem. Elected officials still have to decide what to do about it, how to pay for it, and how to explain their choices. Reporting should examine both the evidence and the response. That is where I want to strengthen my work. My reporting on Helene recovery, infrastructure, flooding, public safety, and public spending has repeatedly brought me to questions that require scientific expertise alongside public records. This mentorship may help me better understand the research, ask more precise questions, and explain the answers clearly. I also bring the perspective of someone living with these concerns. I live downstream of Lake Lure Dam, and landslides affected my property during Helene. Those experiences bring urgency to my questions. Careful reporting helps establish the answers. Readers deserve to know what the evidence shows, where uncertainty remains, and whether officials accurately describe the information guiding their decisions. You also deserve scrutiny of proposed solutions: what they cost, what they are expected to accomplish, and what risks remain. Access to that information matters. As a mostly deaf journalist who relies on written communication, I will continue pressing for written public warnings, records, and explanations that people can read and use in real time. As you consider the candidates seeking your vote, consider how they approach evidence, preparedness, and transparency. Do they support local journalism, even when it’s not parroting a press release? Do they explain weather events clearly in plain English and explain their decisions after them? Make supporting records available? Acknowledge uncertainty? Follow through when a report identifies a risk? Those are practical questions about governing. Thank you for supporting Cops & Congress and the work that makes these questions part of the public conversation. I’m grateful to David Dickson and the CC Now team for this opportunity, and I look forward to bringing what I learn back to you. Annie DanceEditor & Publisher, Cops & Congress — Learn more about this newsletter, ethics policy, how you can help shape this work, and support it. Follow on X and Facebook. Send constructive criticism, fan mail, and tips with public documents for future stories: CopsandCongress@gmail.com ICYMI: View the Cops & Congress archive — Annie Dance is the publisher of Cops & Congress, a newsletter that analyzes what happens when crime, courts, disaster, democracy, and small-town policies collide. Views expressed here are covered by the First Amendment. Dance has a Bachelor of Arts from Manhattan University in Communication with a focus in Journalism and Government. She has been a journalist for over 20 years. Share Upgrade now or give a gift subscription

Oct 20 • 6:56 AM EDT • Science • anniedance.substack.com

'We lost the battle': Local businesses prepare as DEI crackdown hits OEV

New Florida law forces Tallahassee to replace its minority business aid program with a neutral alternative. Some business owners worry about the future.

Oct 20 • 5:03 AM EDT • Business • tallahassee.com

Commentary: Stable jobs support healthier Hoosiers and a more sustainable Medicaid program

Indiana's low unemployment rate is good news for Indiana’s economy, and also matters for the health and stability of Hoosiers.

Oct 20 • 5:00 AM EDT • Health • indianacapitalchronicle.com

GDC Festival of Gaming 2027 moves to four-day format to "create a higher quality, more focused and valuable experience"

"We're concentrating programming and opportunities during the days when the community is most active," say organisers

Oct 20 • 4:37 AM EDT • Technology • gamesindustry.biz

New health science center to be featured at Altrusa Oak Ridge meeting

Altrusa International will host a program on the new 130,000 square foot Roane State health science center.

Oct 20 • 4:10 AM EDT • Science • yahoo.com

New health science center to be featured at Altrusa Oak Ridge meeting

Altrusa International will host a program on the new 130,000 square foot Roane State health science center.

Oct 20 • 4:10 AM EDT • Health • yahoo.com

Pfizer makes ‘business decision’ to end phase 2 trial of autoimmune drug as program’s future uncertain

Pfizer has called time on a phase 2 trial of its CXCR5 antibody in an autoimmune blood disorder, with the company tight-lipped on whether this marks the end of the road for the asset. The Big Pharma had been evaluating the therapy, dubbed PF-06835375, in a phase 2 study of 61 patients with primary immune thrombocytopenia (ITP) that kicked off in 2022, according to the federal trials register. However, Pfizer confirmed to Fierce on Monday that this study had been terminated “due to a business decision.” “The decision to terminate the trial was not based on any safety concerns,” a spokesperson pointed out. At time of publication, PF-06835375 remained listed on Pfizer’s website for both ITP and lupus. A phase 1 study in lupus wrapped up in 2022, according to the trials database. ITP is an autoimmune disorder characterized by a low platelet count. Novartis was at one point evaluating its B-cell-depleting antibody ianalumab—recently approved as Fabhalta to treat immunoglobulin A nephropathy—as a potential treatment ITP. But the therapy struggled to demonstrate a benefit in the clinic for this indication. When contacted by Fierce, Pfizer wouldn’t confirm whether all work on PF-06835375 has been halted, and whether the company has any other plans to explore C-X-C chemokine receptor type 5 (CXCR5) as a mechanism. CXCR5 is found in blood cancers such as diffuse large B-cell lymphoma and mantle cell lymphoma chemokine receptor. However, there is little expression in normal tissue, which has led some drug developers to explore its potential. Vincerx Pharma had at one point been planning to take an anti-CXCR5 ADC into the clinic to treat B-cell malignancies, but that ambition was scrapped due to cash constraints. Where Big Pharma is placing its bets is one of the hot topics being discussed at Fierce Biotech's high-impact event in London next month. Find out more information and register by clicking on the banner below: [ ](https://qtxasset.com/quartz/qcloud5/media/image/where_big_pharma_is_placing_its_bets.png?VersionId=B8JrRbJ.pFUSK1pJgjeWHLGm_18RdLAy)

Oct 20 • 3:59 AM EDT • Business • fiercebiotech.com

Auburn Linebacker Xavier Atkins Dismissed From Football Program

Auburn linebacker Xavier Atkins has reportedly been dismissed from the football program following a disciplinary issue that sidelined him against Georgia. With Atkins no longer on the roster, Alex Golesh and DJ Durkin must rely on Elijah Melendez, Bryce Deas and De'Marcus Riddick against LSU.

Oct 20 • 2:42 AM EDT • Sports • sports.yahoo.com

Calcium-rich whey permeate improves bone health in postmenopausal women, study finds

AFI AFI COPENHAGEN, Denmark, Oct. 20, 2026 (GLOBE NEWSWIRE) -- Twice-daily supplementation with calcium-rich whey permeate supports the maintenance of bone mineral density in postmenopausal women, according to a 12-month clinical study.[1] Declining oestrogen levels during menopause can accelerate bone loss and reduce bone mineral density, increasing osteoporosis risk. The findings come from the RENEW project, a research collaboration investigating how calcium-rich permeate from whey production

Oct 20 • 2:00 AM EDT • Health • finance.yahoo.com

Franciscan Health Dyer adds OrderAhead food locker in partnership with Food Bank of NWI

Technology enhances partnership aimed at fighting Region food insecurity DYER, Ind. – Franciscan Health Dyer now has an OrderAhead food locker thanks to a partnership with the Food Bank of Northwest Indiana and generous donations to the Franciscan Health Foundation. The OrderAhead food locker program was designed by the Food Bank of Northwest Indiana for neighbors with chronic concerns about adequate food access. The lockers allow food-insecure individuals to place an order online for pickup at a scheduled time. “We are thankful to be able to further enhance our impactful partnership with the Food Bank with the addition of the

Oct 20 • 1:15 AM EDT • Health • wimsradio.com

Rogers argues El-Sayed is vulnerable with 2 traditionally Democratic blocs as Obama heads to Michigan

Mike Rogers argues Abdul El-Sayed may lose Black and Jewish voters in Michigan's Senate race during a Sean Hannity town hall on key demographics.

Oct 20 • 12:03 AM EDT • Politics • foxnews.com

Seminoles Mourn the Passing of Former Coach Chuck Amato

He was a fixture on the Florida State sideline for 27 years, and coached many of the program's greatest defensive stars, like Derrick Brooks and Corey Simon. to name a few.

Oct 19 • 11:15 PM EDT • Sports • sports.yahoo.com

Proposed New Visa for Home Health Aides and Nursing Assistants: What Healthcare Staffing Companies Need to Know

A new policy proposal published by the Brookings Institution recommends creating a temporary work visa that would let US employers sponsor foreign home health aides, personal care aides, and nursing assistants to help ease a growing shortage of caregivers. The September 29 proposal, authored by Brookings scholar Tara Watson through the Hamilton Project, would create an “H-1D” visa category built specifically for the direct-care workforce, launching as a pilot program of 30,000 visas per year. It would require employers to pay wages near the top of the local market, guarantee workers a minimum number of weekly hours, and contemplate a potential pathway to permanent residence after six years, although implementing that pathway would require additional changes to immigration law. The H-1D is only a proposal at this point. No H-1D legislation has been enacted, and employers cannot currently sponsor workers under this proposed classification. But if the idea gains traction, healthcare staffing companies could find themselves with both a significant recruiting opportunity and a new set of compliance obligations. This Insight walks through the proposal’s general immigration and employment requirements, then turns to the specific opportunities and challenges it could create for staffing firms.

Oct 19 • 10:59 PM EDT • Health • fisherphillips.com

ACHE’s new rural-focused public health doctoral program welcomes first class of 21

A new doctoral program at the Arkansas Colleges of Health Education in Fort Smith aims to equip healthcare professionals with skills to address rural health disparities and revive services missing from their communities.

Oct 19 • 10:10 PM EDT • Health • arkansasonline.com

Actor, activist Jane Fonda makes appearances, endorsements in Oregon

Actor and progressive activist Jane Fonda made appearances in Salem and Portland to support Oregon Democratic candidates for the November election.

Oct 19 • 8:56 PM EDT • Politics • statesmanjournal.com

Toppenish School District receives $7.5 million federal grant to expand mental health services for students

The BriefThe Toppenish School District has been awarded up to $7.5 million through Project AWARE (Advancing Wellness and Resiliency in Education), a federal grant administered by the Substance Abuse and Mental Health Services Administration (SAMHSA).The grant will provide up to $1.5 million annually over five years to expand mental health services, strengthen substance use prevention and intervention, and improve access to support for students.District officials say the funding will help address identified gaps in services, particularly drug and alcohol counseling at the high school level, and will allow the district to build capacity for long-term mental health support.TOPPENISH, WASHINGTON — The Toppenish School District has been awarded up to $7.5 million through Project AWARE (Advancing Wellness and Resiliency in Education), a federal grant administered by the Substance Abuse and Mental Health Services Administration (SAMHSA), to expand mental health services and substance use prevention for students.District officials said access to mental health resources has been limited, making it difficult for some students and families to get the support they need. The federal Project AWARE grant will help address those challenges by bringing schools and local healthcare providers together to better support students.The grant will provide up to $1.5 million annually over five years to expand mental health services, strengthen substance use prevention and intervention, and improve access to support for Toppenish students. Deputy Superintendent Dr. Jeff Camero said the district is focused on coordinating with service providers in the area to work as a unified team."We made the awareness with the grant. But looking at all the service providers in the area and how can we all together work as a team?" Camero said.Camero said the district wants to use those resources to reach students earlier and provide more support for those struggling with their mental health. The district plans to address a range of mental health challenges, from anxiety and depression to youth suicide risk. Camero emphasized the importance of supporting students in grades eight through twelve, where suicide rates are a particular concern."Making sure from anxiety to depression, making sure that we can help support our students at those levels, but also the youth suicide risk, looking at that as a top in this area, in our grades, you know, eight, for example, eight through 12, looking at suicide rate and looking at how whether we look at the ACES or whatever program we're looking at, that's federal, how that connects and how we can better serve our students with this extra funding," Camero said.The funding will allow the district to bring in additional staff, including mental health and substance use specialists, to work directly with students and connect families with community resources. The district is already posting positions, including a director role, with additional positions expected to follow.District officials are also thinking beyond the grant's five-year timeline. Brittany Kaple, Director of Public Relations for the Toppenish School District, said the intent is to build capacity and establish connections that will sustain mental health services even after the grant funding ends."We do have the director position already posted, with some of our other positions following really close behind that. But the intent is to, you know, it's a five-year grant, so those positions would be funded for that five years. But there's also the intent to build capacity and make those connections so that at the end of the grant, when that money, you know, if that money is not renewed," Kaple said.As student mental health needs continue to evolve, access to drug and alcohol counseling has become an important priority for the district. Kaple said teachers and staff have been raising concerns about the need for more support, especially at the high school level."And that was something that was also an identified need by our high school staff when the superintendent met with them last school year. They said that that was a really great need, something that they felt was a gap in services that we were providing for our students. And so this is going to be one way to help support that need," Kaple said.The Toppenish School District says its goal is to ensure students and families have access to the support they need, both now and in the years ahead. Additional positions, including drug and alcohol counselors and family engagement specialists, are expected to be posted in the coming weeks. News Sunnyside City Council navigates 2027 budget planning Monique Garcia News "Dancing with the Stars" champion J.R. 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