SCROLL NEWS / DISCOVERY
Search headlines
Find the stories shaping the conversation.
Results for " technique " 220 found 🔀 AI-powered Shuffle
The heatwave hacks that will actually help to keep you cool
Should you wear wet socks to bed or point a fan out the window? Can the ‘Japanese door fan’ technique cool a baking hot car? Here’s what the science says
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Scientists measure hidden quantum forces that could power a new generation of pharmaceutical drugs
Researchers invent a laser technique that reveals the hidden forces shaping proteins, advancing a future of precision medicine engineered with quantum precision.
Jana Kramer almost quit “DWTS” because of 'Russian' teaching techniques: 'Do not speak to me that way'
The "One Tree Hill" star bonded with Hannah Brown, who won "DWTS" season 28, over the intense training experience that viewers don't get to see.
This simple twist could bring quantum computers closer to reality
Researchers found that twisting layered sheets of hexagonal boron nitride can dramatically change the light produced by quantum emitters embedded within the material. The technique offers an unexpected new level of control over components that could power future quantum computers, communications systems, and sensors.
DNA time stamps reveal the strawberry’s surprising origins
Researchers have created a new way to reconstruct the evolutionary history of complex plant genomes by analyzing genetic traces left by transposable elements. The technique revealed that modern strawberries were assembled through multiple ancient genome-merging events, shedding new light on how major crop species evolved.
WHO Step-by-Step programme recognized as a promising innovation for mental health in humanitarian settings
WHO, in collaboration with the Pan American Health Organization (PAHO) and Lebanon’s National Mental Health Programme, showcased Step-by-Step at the World Bank Group’s biennial Fragility Forum in Washington, DC. The forum convened more than 1500 representatives from governments, international organizations and civil society to advance the development agenda in the world’s most fragile and crisis-affected communities. WHO was invited to demonstrate Step-by-Step – a digital self-help intervention for depression, alongside innovations presented by Stanford University and Google. The World Bank Group selected Step-by-Step from among more than 50 innovations that they reviewed in the lead up to the Forum.About Step-by-StepStep-by-Step is a free digital tool developed by WHO in collaboration with Lebanon’s National Mental Health Programme and other partners, that helps people manage depression and anxiety on their own, with light guidance from a trained supporter. It uses a picture-based story to walk users through evidence-based techniques for managing common mental health conditions. Users complete five modules, with weekly contacts – of around 15 minutes each – from a trained non-specialist helper, such as a community health worker.Evidence-basedClinical trials in Lebanon involving nearly 1250 participants – including 680 Lebanese participants and 569 Syrian participants – showed that Step-by-Step significantly reduced depression, anxiety and stress, and improved daily functioning. By the end of the programme, a reduction in depressive symptoms of more than 50% was reported by almost half (46%) of Lebanese participants and more than one third (37%) of Syrian participants compared to approximately 14% of those who did not use the programme. Cost-effectiveness analyses further suggest that Step-by-Step may offer a cost-saving response to depression in humanitarian emergencies in low- and middle-income countries.Used globallyStep-by-Step is already in use nationwide in Lebanon and Thailand, as part of each country’s mental health system. In India, the NGO – Kaya Guides – has adapted Step-by-Step for delivery through a widely used messaging app. Together, these programmes have provided thousands of people with evidence-based support for depression. The content is freely available from the WHO website for any organization or country to adapt for their own context.A new implementation guideThe Fragility Forum coincided with the recent launch of WHO’s new practical guide: Psychological self-help interventions: delivering self-help for individuals, featuring Step-by-Step and Doing What Matters in Times of Stress (WHO, 2026). The guide is designed to help governments, health workers, organizations and planners bring evidence-based mental health support to more people, particularly in low-resource and crisis-affected settings.
New plasma trick could unlock smaller, more powerful computer chips
A new technique could solve one of the biggest challenges in making future computer chips from ultrathin materials. Researchers found that coating molybdenum disulfide with oxygen or fluorine lets manufacturers remove just the top layer of atoms much more safely during plasma processing. The result is a cleaner, more controlled path toward smaller and more capable electronics.
The secret behind smoother, better-tasting protein shakes
A new whey protein manufacturing technique could make protein shakes taste better and feel smoother in the mouth. Researchers traced unwanted bitterness to concentrated minerals and found a way to remove them without sacrificing the improved texture.
Scientists Just Discovered A Way To Reverse Aging Using Electricity
The search for anti-aging protocols is a long one, but a group of Stanford scientists may have discovered a new technique involving electricity.
Arson convictions are getting thrown out. Experts blame 'junk science'
At least eight Michiganians convicted of arson have been exonerated since 2012. Some say it reflects agencies using debunked investigative techniques.
Principal Charity Classic: Agronomists use science to prepare greens at Wakonda Club
Agronomists play a crucial role in golf tournaments, using advanced tools and techniques to ensure greens are ready for competition at the Principal Charity Classic.
Scientists Unethically Experiment On the Unborn to Improve Gene Editing Techniques, Bioethicist Says
Genetic researchers are experimenting on unborn children in trials that could have been done on animal embryos, according to one bioethicist.
Science-based approach to aspiration thrombectomy could help physicians achieve more optimised and effective procedures
This advertorial is sponsored by Penumbra. The proliferation of new thrombectomy devices coupled with a deepened understanding of these procedures has led to strategies like ADAPT (a direct aspiration first-pass technique) becoming one of the hottest topics in the neurointerventional space. With this in mind, Alex Solich (Karolinska University Hospital, Stockholm, Sweden) sat down with […]
Notre Dame 2026 Player Profile: Defensive End Keon Keeley
After a detour through Alabama, the former elite recruit Keon Keeley finally arrives at Notre Dame. Can the powerful edge rusher refine his raw technique to anchor the Irish defense?
In a First, Scientists Precisely Edit Human Embryo Genes
Researchers relied on a newer gene-editing technique that may make it possible to engineer embryos, a prospect that has long alarmed bioethicists.
New 3D silicon chip breakthrough could extend Moore’s Law for years
As traditional chip miniaturization slows, researchers have found a way to pack more computing power into the same space by stacking silicon circuits in multiple layers. The new process uses ultra-thin silicon membranes and low-temperature manufacturing techniques to overcome a major obstacle that has long blocked the production of true 3D chips.
New 3D silicon chip breakthrough could extend Moore’s Law for years
As traditional chip miniaturization slows, researchers have found a way to pack more computing power into the same space by stacking silicon circuits in multiple layers. The new process uses ultra-thin silicon membranes and low-temperature manufacturing techniques to overcome a major obstacle that has long blocked the production of true 3D chips.
Scientists just found a faster, cleaner way to extract lithium for EV batteries
A breakthrough lithium-extraction method could help solve one of clean energy’s dirtiest problems. Researchers at Columbia Engineering have developed a fast new technique that pulls lithium directly from salty underground brines using a temperature-sensitive solvent, avoiding the giant evaporation ponds that can take years and drain precious water supplies. Even better, the method works on low-quality lithium sources that current technologies struggle to use.
BATMAN to the rescue: TMVR technique helps cardiologists reduce risk of LVOT obstruction
LVOT obstruction is a serious complication of TMVR. BATMAN may help protect patients from LVOT obstruction without leading to any additional risks.
Ancient chemistry trick unlocks new type of glass that traps CO2 and hydrogen
Researchers have discovered how to fine-tune a futuristic type of porous glass that can trap gases like CO2 and hydrogen. Inspired by centuries-old glassmaking techniques, the team added sodium and lithium compounds to make the material easier to process and shape. The breakthrough could accelerate the development of high-performance materials for clean energy, gas storage, and advanced manufacturing.
Scientists use DNA from poop to save the world’s rarest marsupial
Scientists in Australia are using cutting-edge DNA techniques to help save one of the world’s rarest marsupials — the critically endangered Gilbert’s potoroo, with fewer than 150 left in the wild. By analyzing tiny traces of DNA in the animals’ scat, researchers uncovered clues about the elusive fungi the potoroos depend on for survival. The findings could help conservationists identify safer new habitats and establish backup populations before disasters like bushfires wipe them out.
Neanderthals dined on shellfish much earlier than humans
Many of their harvesting techniques are similar to ones used today.
Scientists May Have Found the Blueprint of the Human Body at the Bottom of the Ocean
Scientists discovered that the brainless sea anemone build their bodies with a technique common in bilaterians... which is what humans are.
Faig Ahmed Weaves Mysticism, Science, Technology, and Craft into 'The Attention'
Curated by Gwendolyn Collaço, Ahmed's Venice Biennale presentation expands upon the dialectic between digital processes and hand-crafted techniques.
Paleontology rocked by discovery of organic molecules in 66-million-year-old dinosaur bones
Scientists have uncovered compelling evidence that dinosaur fossils may still contain traces of their original proteins, overturning a long-standing belief that fossilization destroys all organic material. In a remarkably well-preserved Edmontosaurus fossil from South Dakota, researchers detected remnants of collagen — the main protein found in bone — using advanced techniques including mass spectrometry and protein sequencing.
The No. 1 most underrated communication skill—it's a simple but 'powerful' technique that can save a conversation, says expert
Sometimes the most important skill is "knowing when not to say the thing you're about to say" and pivoting, says negotiation expert Kwame Christian.
Clemson Defense SWOT: Weaknesses & Opportunities
They say college football has become a big business and its true. One well-known business technique is called a SWOT analysis. Inspired by the Talkin’ Yanks podcast, I will bring you a SWOT analysis for Clemson football. In this edition we take the Weaknesses and Opportunities portion for the 2026 Clemson Tiger defense. Weakness: There […]
Steve McComas: Trusting science when easy answers elude us
Using this technique, I have found sunfish are opportunistic. If they find a patch of edible food, they will gorge themselves.
Rare Pink Katydid Slowly Transforms Green and Upends Camouflage Science
Camouflage is a widely studied antipredator technique that we thought we understood. A rainforest insect, however, is rewriting the textbooks on the subject as it reveals previously unseen behavior. O...
Anthropic introduces 'dreaming' technique for AI agents
Anthropic introduces 'dreaming,' a technique for AI agents to self-improve within the Claude Managed Agents tool.
Finding 'hidden sperm': AI offers hope to men previously told they were infertile
Millions of men experience azoospermia, where they produce little to no sperm. A new AI-powered technique offers hope to couples looking to have children.
Viewpoint: A career in science is possible, and worth it
Starting a career in science is exciting, but also demanding, with researchers often faced with intense competition, long working hours and high levels of stress. A pioneer in the field of mass spectrometry, Carol Robinson has been there. She speaks with Science|Business on the importance of creating a supportive environment, particularly for women.Robinson did not wake up one day thinking that she would become a scientist. It was only late in school that she developed an interest in chemistry. “The more you work at something, the more you think, actually, this is fascinating. So, I went much further and deeper than I ever needed to pass the exam. And then I loved it,” she says. “I thought, I’m going to give it my all. I’m going to enjoy it while I’m here. But I didn’t think this would be my career for 50 odd years.”She left school at 16 to become a lab technician with the drug company Pfizer, which is where she first worked with mass spectrometry. Fascinated, she was encouraged to take a part-time degree and then a PhD. She went on to do pioneering work in native mass spectrometry, a technique that is used to study protein structures in their natural state, paving the way for breakthroughs in drug discovery. She also broke new ground by becoming the first female professor of chemistry at the University of Cambridge, and then the first female professor of chemistry at the University of Oxford, her current home.She now wants to show young researchers that a career in science is worth it. “Sometimes, I believe the culture isn’t very encouraging, and that’s something I have worked on,” Robinson says.In 2021, she launched the Kavli Institute for Nanoscience Discovery at Oxford, whose acronym gives a sense of what she hopes it will achieve. “Maybe it is corny,” she says. “It’s just a reminder that I would like it if we could all be kind to each other and supportive, especially for early-career researchers of either gender, because there’s quite a big attrition rate in science, and maybe it just doesn’t feel like a very friendly place to work.”And yet, a career in science comes with a lot of flexibility. “There are few careers where you have that amount of freedom, to go to conferences, to the library. Just because you didn’t see me didn’t mean I wasn’t working,” she says. “And I’m excited to come in every day. So, I don’t want people to think it’s a terrible place.”Gender equality is also important when it comes to the quality of science as a career. “The more women we have, the better it becomes,” Robinson adds.Imposter syndromeAccording to EU data, women outnumber men in university education but account for just about a third of graduates in science, technology, engineering and mathematics (Stem). And while the number of women working as scientists and engineers in the 27-member bloc is on the rise, their representation remains below that of men, at 41%. This discrepancy is even more pronounced in top-tier functions across these fields, where women fill just 20% of positions.Having supervised many young scientists, Robinson sees that women continue to have a greater propensity than men to doubt their abilities, a feeling she once shared. “When I was doing my PhD at the University at Cambridge, I really felt like an imposter,” she says. “I don’t think I ever felt I deserved to be there or owned it and was proud. I just thought I was lucky.” Later on, she adds, “I was always that person who said, I can’t apply yet because my CV is not strong enough.”She has now made it her job to encourage women to break with this imposter syndrome. For example, rather than calling for volunteers to give a lecture in the groups that she mentors or teaches, which nearly always results in men stepping forward, she goes straight to the women, “because I know they won’t push themselves forward.”But the gender gap in science is not just down to imposter syndrome. The “obvious” reason, Robinson says, and the reason that is on everybody’s mind when discussing workplace gender equality, is the balance between work and raising a family. Her own path was to choose between the two, taking an eight-year break after completing a postdoctoral training fellowship to bring up three children. And she continues to advise women not to work part-time while they raise a family. “You’ll just get half the pay and continue to work full-time because you are not able to fit everything in,” she says. “You should be able to have a family and come back to have the career that you want.”The solution is for men to also take career breaks. “That kind of evens it up, so that it’s not such a big thing for women,” Robinson says. “I always encourage men in my groups to do that. I think it’s important to take your share of the duties.”Support produces resultsAccording to the Women in Stem Network, a UK advocacy group, countries with strong childcare systems and equal pay policies retain more women in technical careers. In Europe, these are primarily found in the Nordic region and parts of central Europe.At the EU level, the European Commission asks all Horizon Europe applicant organisations to have a gender action plan in place. Since this criterion was introduced in 2021, the share of women leading consortia has increased to 31%, against 23% in Horizon 2020. Their overall participation, however, has risen just 1%, to 38%. After trying to weaken the requirement for gender action plans in 2025, the Commission now intends to adopt a plan for supporting women in research and innovation.Related articlesCommission scraps plan to water down gender requirements in HorizonHow gender balance can swing who wins Horizon Europe fundingRobinson herself has benefited from three Advanced Grants from the European Research Council. “I was extremely honoured and privileged to get those, because they really allowed me to fuel my passion,” she says. “Without that, it would have been a much harder slog.”Beyond applying gender rules, she says that more work is needed on translational enterprise, where women are, once again, largely underrepresented. The European Patent Office found that only 13.8% of applications were filed by women in 2022. “We have so many more women doing amazing science; why do they feel it’s not a thing to have a company?” she asks.She founded her own spin-out company, OMass Technologies, in 2016, and remains chair of its scientific advisory board now that it trades as OMass Therapeutics. As for research, Robinson is now studying how changes in the brain may be linked to depression, using port-mortem tissue. “We’re hoping to publish soon,” she says. “We had to consult with a lot of people who knew a lot more about the brain than we did. So, we’ve learnt a lot, and that’s always a lot of fun to learn a new thing. That’s what keeps you going.”
Denuvo Has Been Fully Cracked And 2K Is Fighting Back
Using a relatively new bypass technique, hackers claim to have effectively cracked all games using Denuvo protection software
MIT scientists turn chaotic laser light into powerful brain imaging tool
Scientists at MIT discovered that chaotic laser light can spontaneously form a highly focused beam instead of scattering—if the conditions are just right. This “pencil beam” enabled them to image the blood-brain barrier in 3D at speeds 25 times faster than existing techniques. The method also lets researchers watch how drugs move into brain cells in real time. It could dramatically accelerate the development of treatments for neurological diseases.
Vanderbilt Health clinicians seek to improve care for those with traumatic brain injuries
CBIS training covers the cognitive, psychological and social consequences of brain injury; behavioral approaches for managing challenging behaviors and promoting positive skills; and techniques for effectively working with families of individuals with brain injury.
MIT researchers find self-organizing “pencil beam” laser could help scientists design brain-targeted therapies
After a surprising discovery that overcomes a longstanding problem in fiber optics, MIT researchers demonstrated a biomedical imaging technique that is faster and more precise than other methods, which could help scientists and clinicians study new brain therapies.
Habit-stacking to reach health and wellness goals
Habit-stacking is a habit formation technique that’s gotten a lot of attention in recent years.
How to use habit-stacking to reach your health and wellness goals
Habit-stacking, a technique that’s gotten a lot of attention in recent years, can create a structured and effective routine when motivation alone isn’t enough.
Scientists just discovered a 60-foot long, kraken-like octopus
The discovery, using novel techniques to analyze fossilized jaws, details how colossal octopuses hunted the Late Cretaceous depths, competing with apex predators.
AI-driven sports technology from Carnegie Mellon students draws interest from Mark Cuban
More than 68 million Americans play a racquet sport, but improving their skills can be difficult. Costs for lessons are becoming increasingly expensive, and feedback for technique isn’t always individualized. But three Carnegie Mellon University students think they have an answer. They launched a company called ServeSense. Pitching their technology
This new camera captures what happens in a trillionth of a second
Scientists have unveiled a breakthrough imaging method that can capture the hidden details of events unfolding in trillionths of a second. This new technique doesn’t just track how bright something is—it also reveals subtle structural changes that were previously invisible, all in a single shot. By effectively turning ultrafast phenomena into detailed “movies,” researchers can now watch plasma form, electrons move, and materials transform in real time.
New imaging technique helps scientists see the inside of living cells to study how cancer spreads and grows
New fluorescent dyes allow scientists to watch cancer activity inside living cells in real time, opening new possibilities for treatment.
Sunbirds suck, scientists find. Hummingbirds don’t.
Two unrelated groups of nectar eaters, hummingbirds and sunbirds, evolved different techniques to slurp the sweet liquid from flowers. The tongue suctioning employed by sunbirds is unique among
A look at 'super agers' and the science behind longer, sharper lives
For thousands of years, humans have tried to avoid growing old. Billions are spent every year on potions and procedures to make us look younger, feel younger and think younger. It’s a hugely profitable, but ultimately fruitless hunt. But science has started to zero in on some proven techniques. Horizons moderator William Brangham explores that with Dr. Eric Topol and Dr. Sandra Weintraub.
Scientists Break Optical Limits With Quantum Dot-Powered Nanoscopy
A powerful new microscopy technique unveils hidden nanoscale light interactions, offering a glimpse into physics that conventional tools cannot resolve.
Kyle Hamilton praises Mike Mickens' technique and coaching style
Ravens safety Kyle Hamilton praises new DB coach Mike Mickens' 'rare' technique-oriented style, recalling their Notre Dame days.
Scientists Capture Hidden Electron Patterns Inside Quantum Materials
A new imaging technique uncovers how electronic patterns in quantum materials evolve unevenly across space and temperature.
Scientists Unveil Microscopy Breakthrough That Reveals “Invisible” Molecular States
Scientists have introduced a microscopy technique that reveals a hidden layer of chemistry involving molecules that normally evade detection.
Hidden weak spots in HIV and Ebola revealed with breakthrough nanodisc technology
A new nanodisc-based platform lets scientists study viral proteins in a form that closely mimics real viruses, revealing how antibodies truly recognize them. This approach uncovered hidden interactions in viruses like HIV and Ebola that traditional methods missed. By recreating the virus’s membrane environment, researchers can better understand how immune defenses work. The technique could speed up the development of more effective vaccines.
The Universe is expanding too fast and scientists still can’t explain it
A major international effort has produced an ultra-precise measurement of the Universe’s expansion rate, confirming it’s faster than early-Universe models predict. By linking multiple distance-measuring techniques, scientists ruled out simple errors as the cause of the discrepancy. The persistent “Hubble tension” now looks more real than ever. It could mean our current model of the cosmos is incomplete.
“AI polls” are fake polls
A few weeks after Donald Trump’s second presidential win, I took the train up from London (where I was living at the time) to Oxford to attend a conference on polls and forecasts of the 2024 election. Most of the attendees were pollsters or academics, but I also watched presentations from Aaru and Electric Twin, two companies that do what is interchangeably called synthetic sampling, silicon sampling, or synthetic audiences. Stripped of startup jargon, that means they use large language models (LLMs) to simulate responses to public opinion polls by having AI agents take on the role of survey respondents. I had already heard of Aaru thanks to some articles with eye-catching headlines like “No people, no problem: AI chatbots predict elections better than humans” in the months leading up to Election Day. The founders were making some big, some might even say far-fetched claims, such as: “within two years, we will simulate the entire globe — from the way crops are grown in Ukraine to how that impacts production of oil in Iraq, trade through the strait of Malacca, and elections for the mayor of Baltimore.” When Semafor asked Aaru’s cofounders — Cameron Fink and Ned Koh — about my boss, they said “we respect all those who came before us.” Nate (as he so often does) shared his thoughts on Twitter: Fink and Koh were relatively good-natured about this back-and-forth when we spoke at Oxford. They even offered to mail me one of the t-shirts featuring Nate’s quote they apparently had made. I never took them up on the offer, which I now somewhat regret. These synthetic sampling companies fell off my radar for a while, but they do still exist. In fact, Aaru recently received a $1 billion valuation. Is what they’re doing anywhere close to the most important frontier in AI development? Not by a longshot, especially when Anthropic just developed a model so adept at exploiting software vulnerabilities that it’s only being released to 40 companies. Still, silicon sampling is increasingly finding its way into public polling. Axios reported in March that “a majority of people trust their own doctors and nurses” based on findings from Aaru — without mentioning that the “people” in that sentence were actually LLMs. Around the same time, the Public Sentiment Institute “boosted” their online sample of 373 real survey respondents with 114 AI agents.1 (Spoiler alert: even the co-founder of Electric Twin doesn’t think that’s a particularly defensible approach.) Polling companies like Qualtrics and Ipsos are also developing synthetic data panels. So, what should we make of these … “polls”? Let’s get one thing out of the way: whatever they are, they’re not polls in the way that term is usually defined. Subscribe You can’t replace polls with AI On one hand, using LLMs to essentially make up fake survey respondents sort of sounds like the dumbest idea ever, one that will at best imperfectly replicate real polls while introducing all sorts of biases. On the other hand, with LLMs improving at a remarkable, perhaps even alarming rate, maybe that means I’m a dinosaur at the ripe old age of 24 because I still want to rely on polls that talk to actual people. I’m not going to argue that synthetic samples are completely useless. In fact, as I’ll return to later, there is evidence that some techniques can replicate topline survey results quickly and cheaply. But the marketing from certain companies can be slightly optimistic. “No traditional poll will exist by the time the next general election occurs,” said Fink in 2024. We’re just 206 days away from the midterms, and based on the fact that I still have to collect a bunch of polls every day, I’d say he should have run that prediction by a sample of AI agents before the interview.2 To see why synthetic samples can’t replace polls, here’s a quick primer on how they work. The simplest version of these models involves taking a LLM (like ChatGPT or Claude), giving it a demographic profile (e.g., a white, college-educated woman who lives in Utah and makes $70k a year), and then asking it to respond to a survey question. You repeat that process a few thousand times using different demographic profiles and end up with a sample of synthetic survey responses. The actual models used by private companies are more sophisticated than this, usually because they incorporate more hypothesized demographic characteristics for each agent and provide them with extra information. Aaru, for example, feeds agents a diet of news and information they’d be likely to consume, while Electric Twin incorporates their customers’ proprietary data about the audience they’re trying to replicate. The way Ben Warner, the co-founder of Electric Twin, explained it to me was “we have a large amount of data on […] for instance, 5,000 people. Can we make an accurate prediction of how they would respond to another question?” Still, it should be obvious why synthetic samples can’t replace polls. Polling is fundamentally a data collection process. We might use surveys to make predictions by feeding them into election forecasts, but the main purpose of a poll isn’t prediction, it’s gathering new data about what people think and how they feel. Silicon sampling, on the other hand, produces no new data. It’s simply a model: you input LLM training data, demographic prompts, and a bunch of other information, and it spits out a prediction for what a poll would say. We love models here, but models aren’t polls. That difference is an important philosophical sticking point for most pollsters I talk to. “I think politics should stay away from [synthetic sampling], because we’re trying to […] represent the voice of the people,” said Natalie Jackson, a vice president at GQR Insights. Democratic pollster John Hagner told me: “I think I’m just incredibly skeptical of this idea. I don’t think it’s research. At that point, you’re asking the machine to tell you what you already believe.” Hagner has seen some presentations of early synthetic sampling experiments, but so far, “if it’s being used in a campaign, people are keeping it incredibly quiet.”3 But Eli, I hear you saying, aren’t polls themselves increasingly governed by modeling decisions? Indeed they are: pollsters’ choices on which sampling method to use, how to define their likely voter models, and how to weight their samples can and do lead to dramatic differences in the results they publish. Aaru even referenced these limitations in the methodology statement included with that maternal mortality “poll” — although I’m using the term “methodology statement” loosely here, because it doesn’t really explain how the model works at all. We can ignore the (frankly preposterous) implication that synthetic sampling isn’t subject to a separate set of biases. The important point is that there’s still a meaningful difference between using weighting and other statistical techniques on actual polling data and using a model to predict what a poll would say. The latter is far closer to election forecasts or techniques like MRP — potentially useful models, but not a replacement for polls.4 To be fair, other synthetic sampling companies are perfectly happy with the distinction between polls and models. Warner compared polling and synthetic sampling to different tools in a toolbox. “The mistake I think we make is we think that these new tools should either work in exactly the same way or somehow replace these old tools,” he said. “Rather than thinking of it as, okay, so we’ve always had the hammer, we’ve always had the screwdriver, now we’ve got a saw. But don’t use a saw to try [to] do the job of a hammer.” A quick comment from Nate Eli didn’t ask me for a comment — rather rude of him, don’t you think? But since I’m editing this story, I figured I’d add a few quick thoughts rather than putting words in his mouth. Beyond the frequently misleading marketing, what bothers me about the AI “poll” hype is that as AI tools make statistical inference cheaper and/or better (note that these are not synonyms) that actually increases the comparative value of collecting original data. You might be able to train a model to make a reasonable estimate of what some hard-to-reach poll respondent would say — say, a young Black man who voted for Trump. (Such a person checks a number of boxes for a voter who is usually hard to reach in surveys.) Indeed, this is closely related to what models like the Silver Bulletin forecast already do. They essentially smooth out the kinks in noisy survey data by making inferences based on past voting patterns or national polls or surveys of other states. But you don’t actually know what these voters think unless you’re reaching them directly. If there’s a shift in opinion among this subgroup, you’re not going to detect it. So if I were running a campaign, I’d invest more in going the extra mile to find a representative sample of those voters. And then I’d hire some smart quants — or Claude? — to figure out the implications for campaign strategy based on proprietary data that my competitors didn’t have access to. -Nate Silver Are these models any good? If synthetic surveys are just a new type of model, the next obvious question is whether the models are at least accurate. The answer very much depends on who you ask. On one end of the spectrum, you have the maximalist argument that synthetic sampling is more accurate than actual polls. “It’s an incredibly challenging problem to go to someone and say ‘hey, we’re going to be more accurate at predicting human behavior than you, even when you talk to your customers directly’,” Koh recently told CNBC. In his view, synthetic sampling isn’t a saw to polling’s hammer, it’s “magic.” There’s certainly evidence that synthetic samples can replicate certain survey toplines. But if Aaru does have any examples of their approach outperforming the polls, they’re keeping those to themselves.5 Aaru’s 2024 election model, for example, had Kamala Harris leading in Michigan, Nevada, Pennsylvania, and Wisconsin on November 4th. And although they’ve since taken down their forecast page, they gave Harris a 50.5 percent chance of winning the race on November 2nd.6 After the election, Fink told Semafor he was happy enough with those results because they were “within margin of error,” a term that is completely meaningless when applied to a “sample” of AI agents. And of course, Aaru says their models have improved since 2024, so supposedly now they’d be more accurate than the polls? Still, their stronger argument is on cost: “We are significantly faster and cheaper than traditional polling, and still more accurate,” said Fink. The first two claims are undeniably true, but the third brings us to the opposite end of the spectrum. Both Jackson and Hagner are skeptical that these models are reliable for anything beyond replicating common survey toplines. “I just […] don’t think the machines are what we want when we’re looking for nuanced views. My example on this is people in Arizona and Nevada in 2024 who voted for Trump and voted for expanding abortion in their states on ballot initiatives,” said Jackson. Hagner identified another issue. Maybe the synthetic respondents, like sycophantic LLMs, are inhuman in one important way: they’re too nice. “The reports that have come through at the meetings that I’ve been at are that the early experiments on this, they cannot get respondents to be as racist or sexist or, frankly, as negative as human respondents,” he said. Academic research mostly agrees on this point. While there are some papers that show promising results when using LLMs to replicate polling data, most show that LLMs suffer from various quirks like producing too few “don’t know” responses and can seriously overpredict the favorability of politicians like Donald Trump and Kamala Harris. They also seem to struggle with too little variation between demographic subgroups, so the difference in predicted opinion between Democrats and Republicans, for example, is too small. When I asked Warner about these studies, his response to these papers was that just because academics can’t get synthetic sampling to work doesn’t mean that the technique doesn’t work in general. “Actually, the argument is, okay, yours does not [work]. That does not mean […] for this complex set of machinery, which uses a lot of investment, a lot of time, a lot of money, you can’t get it to work.” Cards on the table, I’m somewhat sympathetic to this argument because academics aren’t exactly great at making election forecasts. Usually, the people with skin in the game are the most accurate. Warner’s argument is that the approach Electric Twin takes — which includes, for example, making multiple predictions for each synthetic respondent using different models and prompts and subsequently averaging those to get a final prediction in a sort of ensemble forecast — produces better results than the simpler academic models. Warner shared a comparison between his method and the method from a recent academic paper with me, and Electric Twin was indeed able to get more accurate replication. But even still, he acknowledged that synthetic sampling “is not a crystal ball.” “If you asked me, do I think using other data sources will be more accurate than asking somebody who they will vote for, I would probably say no. But if you asked me ‘would your system be useful for our turnout modeling today?’ I would say yes.” For better or worse, it looks like the method is already getting more popular in the market research world. Most of the clients Aaru touts these days are businesses like EY and McDonald’s. And AI will probably begin to pop up in other parts of the political polling process. Pollsters are already using it to code open-ended survey responses, and some firms, like YouGov, are testing using LLMs to ask survey respondents questions. More worryingly, one danger to actual polls is that AI agents can be used to infiltrate online surveys. Most online polls use various checks to prevent that from happening, but there’s conflicting evidence on how effective those filters are and how prevalent AI agents currently are in online panels. If those agents ever become impossible to detect, it might spell the end of online polling, but the solution isn’t to replace all of your respondents with ChatGPT. Silver Bulletin is a reader-supported publication. To receive new posts and support our work, consider becoming a subscriber. Subscribe 1 That particular poll obviously doesn’t meet Silver Bulletin standards for aggregation. But we exclude all Public Sentiment Institute polls from our averages because we classify them as an amateur polling firm. 2 You could argue that Fink meant the next presidential election, but (a) I’m also confident we’ll still have real polls in 2028 and (b) in that case he should have asked an LLM to define “general election.” 3 Quick caveat: that’s reporting from a Democratic pollster. It’s possible that Republicans are more willing to use AI in political campaigns. 4 Indeed, Silver Bulletin does not include “polls” produced by MRP in our forecasts or averages, and we think it’s extremely misleading when their practitioners describe them in a way that suggests original data had been collected among a large number of states or Congressional districts. 5 A recent report from Aaru and EY did show two examples of a synthetic estimate being closer than a survey to a real-world benchmark — but I’d take those findings with a grain of salt because the report reads more like an ad and didn’t involve any sort of prediction being made ahead of time. 6 For comparison, our odds for Harris on the same day were 48.2 percent.
The World’s First Computer Sank 2,000 Years Ago. Science Finally Solved One of Its Biggest Mysteries.
Using, oddly enough, techniques developed to analyze gravitational wave signals.
The World’s First Computer Sank 2,000 Years Ago. Science Finally Solved One of Its Biggest Mysteries.
Using, oddly enough, techniques developed to analyze gravitational wave signals.
Scientists say we’ve been wrong about what makes sprinters fast
A new international study is shaking up how we think about elite sprinting, arguing there’s no single “perfect” running style behind the world’s fastest athletes. Instead, speed emerges from a complex mix of an individual’s body, coordination, strength, and training—meaning every top sprinter moves differently. Using examples like rising Australian star Gout Gout, researchers show that unique physical traits can produce world-class speed without copying anyone else’s technique.
Scientists map the brain’s hidden wiring using RNA barcodes in major breakthrough
Researchers have developed a cutting-edge technique that uses RNA “barcodes” to map how neurons connect, capturing thousands of links with single-synapse precision. The method transforms brain mapping into a sequencing task, making it faster and more scalable than traditional approaches. In mice, it revealed surprising new connections between brain cells that were previously unknown. This could open the door to earlier detection and targeted treatment of neurological diseases.
On plant health and embracing new plant-breeding techniques in South Africa
The major challenge currently confronting South Africa’s agriculture is the spread of foot-and-mouth disease. For many farmers across the country, the most urgent tasks are both securing sufficient vaccines and rolling them out quickly in the coming months, particularly as the beef and dairy industries continue to suffer big losses. There is also pressure on sheep, goats, and other livestock to prevent the disease from spreading. As efforts to get the country through this monumental challenge continue, I believe it is important to sharpen our focus on the broader task at hand: strengthening biosecurity. This covers both animal and plant health. In recent years, we haven’t focused much on plant health, except a few times, such as when we had a goss’s wilt scare in the maize industry, a few cases of citrus black spot, or cases of sclerotinia in sunflower seeds. But the fact that South Africa managed to control the outbreaks of these particular diseases when they occurred a few years ago was due to organized agricultural and government scientific capabilities, and, most importantly, the availability of crop protection or agrochemicals necessary to address some of them. Therefore, as the animal health division in the Department of Agriculture focuses on the pressing challenge of the day, the foot-and-mouth disease, there is an opportunity for the plant health division to assess if they have all the requirements to tackle any outbreak that may occur on fruits, vegetables or crops in future. The challenge with crop diseases is that they can spread quickly and cause much more rapid damage in the field than we typically see with livestock. Therefore, speed is everything in ensuring the appropriate controls are available. I raise this as an important area, particularly given the drastic climate variation we observe across the country. The production conditions in some areas have changed noticeably over time, which may introduce new risks. The other essential part is ensuring that South Africa has access to the best crop protection technology available in the market. Many technology developers worldwide have operations in South Africa. Therefore, the Department of Agriculture, along with the Agricultural Research Council, must continuously interact with technology developers to assess the various crop protection technologies they are releasing globally and determine their suitability and need in South Africa. This will require a proactive approach from the government, unlike the current approach, in which technology developers typically approach regulators with new technologies. The government, recognising the food security risks, must take a proactive approach to ensure that South African farmers have access to the latest crop protection technologies, thereby safeguarding the country’s food security. Beyond crop protection, we must never forget that South Africa’s agriculture is key to ensuring that the country is the most food-secure country at the national level in sub-Saharan Africa. South Africa is also the only African country in the top-40 global agricultural exporters, having more than doubled since 1994 on the back of the adoption of high-yielding seed cultivars. South Africa has been the only African country to adopt a bold approach to embracing science and adopting genetically engineered seeds for grains and oilseeds in the early 2000s. Since then, we have seen crop yields improve noticeably, contributing to the gains we mentioned above. But ensuring that South Africa improves further is not a given. The key lies in South African regulators’ attitudes towards new technologies. We have to maintain a progressive approach and not give in to the politics of non-food and non-scientific voices that shout on the sidelines. Food security is national security, and the government must ensure we progress, leaning on science. Therefore, the registration of high-yielding new genomic techniques is required. South Africa cannot afford to fall behind the EU, the USA, South America, and many of its competitors in global agriculture. The Department of Agriculture’s crop science division must adopt a progress-and-science-embracing approach for the good of the country. Thanks for reading AgriView! Subscribe for free to receive new posts and support my work. Subscribe Share
Train transfer hub linked to reduced healthcare spending
Researchers from Osaka Metropolitan University and Japan System Techniques Co., Ltd. evaluated the 2019 Osaka-Higashi Line station openings using a natural experiment and health insurance claims. While the overall rail-line effect was not significant, Shigino Station, a well-connected transfer hub, showed an estimated cumulative reduction of about JPY 62,500 per medically treated person over four years, highlighting that station connectivity and local context may determinewhether new stations deliver healthcare cost benefits.
Sony's gaming division just bought an AI startup that turns photos into 3D volumes
Sony purchased an AI startup called Cinemersive Labs to help improve rendering techniques and gameplay visuals on future games.
LA Chargers help high school athletes learn lifesaving CPR
More than 250 high school student-athletes from across the Los Angeles Unified School District spent a day learning about heart health alongside Los Angeles Chargers players.Students learned hands-only CPR, met Chargers players Elijah Molden and RJ Mickens in UCLA Health Sports Performance Training, Powered by Exos, and enjoyed lunch on the patio at Huddle for Heart Health, held March 19 at The Bolt, the Chargers’ official practice facility in El Segundo. RJ Mickens, left, and Elijah Molden joined more than 250 LAUSD high school students at the Huddle for Heart Health event. (Photo courtesy of Joaquin Torre/Los Angeles Chargers) Along with learning CPR techniques, students practiced performance training on the LA Chargers practice field in El Segundo. (Photo courtesy of Joaquin Torre/Los Angeles Chargers) LA Chargers defensive back RJ Mickens visits with high school students at the Huddle for Heart Health event. (Photo courtesy of Joaquin Torre/Los Angeles Chargers) The event was presented by UCLA Health, the American Heart Association, the Los Angeles Chargers and LAUSD.Hands-only CPR is a lifesaving skill, said David Sato, MD, board president of the American Heart Association Los Angeles.“We save more lives when we work together,” said Dr. Sato. “This collaboration with UCLA Health and the Los Angeles Chargers to teach students how to perform hands-only CPR helps ensure more families in Los Angeles have someone ready to act in a cardiac emergency when seconds count.”Hands-only CPR is a lifesaving procedure for cardiac emergencies that doesn’t involve rescue breaths. It involves pressing hard and fast in the center of the chest of a teen or adult who has collapsed. Pressing can be done to the beat of the Bee Gee’s hit “Stayin' Alive, which, at 100 beats per minute, is the minimum rate at which to push during hands-only CPR, according to the American Heart Association. LA Chargers defensive back Elijah Molden, standing, helps high school students learn CPR skills. (Photo courtesy of Joaquin Torre/Los Angeles Chargers) Most cardiac arrests that don’t happen in the hospital happen at home, and hands-only CPR is as effective as CPR with breaths in the first minutes following a cardiac emergency.
Apple Will Push Out Rare ‘Backported’ Patches to Protect iOS 18 Users From DarkSword Hacking Tool
As a DarkSword takeover technique spreads, Apple tells WIRED it will release fixes for millions of iPhone owners who remain on iOS 18 rather than force them to update to iOS 26 simply to be protected.
Scientists achieve ‘impossible’ solar efficiency in renewables breakthrough
‘Spin-flip’ technique promises to shatter efficiency limits
The science of the warm-up: From ridicule to RAMP, and the nightmare of losing a player to injury
Player warm-ups, whether for training or on matchday, have become part of the normal routine but there is technique behind making them work
Scientists just found a way to store massive data using light in 3 dimensions
A new holographic storage technique uses light in three dimensions to dramatically increase how much data can be stored. It encodes information throughout a material using amplitude, phase, and polarization, rather than just on a surface. An AI model then reconstructs the data from light patterns, simplifying the process. This could pave the way for faster, denser, and more efficient data storage systems.
Vanderbilt Lung Transplant Program sets new record
The Vanderbilt Transplant Center is now the second largest lung transplant center in the United States by volume, with 149 lung transplants in 2025, the most ever in one year at Vanderbilt Health. The Vanderbilt Lung Transplant Program leads the nation in organ preservation and regeneration and is among the best in long-term outcomes, demonstrating the success of the interdisciplinary team in caring for these complex patients. Several features make the program unique in the United States, said Konrad Hoetzenecker, MD, PhD, professor of Thoracic Surgery and surgical director of the Vanderbilt Lung Transplant Program. Vanderbilt serves as a “second opinion center” and accepts most complex candidates that are turned down by other centers due to increased perioperative risk. This includes patients over 70 years old, patients requiring combined procedures with their transplant, multiorgan transplantations and sensitized patients (individuals who have pre-formed anti-HLA antibodies who are at higher risk for complications). The expertise and excellent outcomes have attracted patients far beyond the borders of Tennessee; almost half of Vanderbilt Health’s lung transplant recipients come from out of state. “Another unique feature is our minimally invasive transplant program,” Hoetzenecker said. “By using distinct surgical instruments and techniques, the incisions can be kept as small as 7 to 8 centimeters, which results in better healing, less pain and faster recovery. “This minimally invasive approach is embedded in an Enhanced Recovery After Surgery (ERAS) protocol, a multimodal, evidence-based perioperative care pathway designed to reduce surgical stress, minimize complications and speed up recovery. Our unique ERAS protocol, by a dedicated interdisciplinary approach, aims to improve recovery after lung transplant and reduce ICU and hospital stay.” The lung transplant program recently celebrated a milestone — 1,000 lung transplants since the program began in 1990. “This significant achievement reflects the concerted effort of a multidisciplinary collaboration by the Departments of Thoracic Surgery, Medicine, Anesthesiology and Critical Care,” said David Erasmus, MD, associate professor of Medicine and medical director of Vanderbilt Lung Transplant. Lung transplants have been attempted since the 1960s, but they were largely unsuccessful until the 1980s, when surgical techniques were refined and new antirejection drugs proved effective. Patient outcomes steadily improved from the 1990s to the present. Vanderbilt’s fourth lung transplant recipient in 1990, Pam Everett, is the longest-living, single-lung transplant known in the world, recently celebrating 35 years since her transplant. The Vanderbilt Lung Transplant surgical team is led by Hoetzenecker and Caitlin Demarest, MD, PhD, the surgical director and associate surgical director of the Vanderbilt Lung Transplant program. Erasmus is the medical director of Vanderbilt Lung Transplant along with Anil Trindade, MD, associate medical director and associate professor of Medicine.
Scientists just found a hidden 48-dimensional world in quantum light
A routine quantum optics technique just revealed an extraordinary secret: entangled light can carry incredibly complex topological structures. Researchers found these hidden patterns reach up to 48 dimensions, offering a vast new “alphabet” for encoding quantum information. Unlike previous assumptions, this topology can emerge from a single property of light—orbital angular momentum.
New controls can stretch, blur and even reverse quantum time flow
In new research published in Physical Review X, scientists have designed quantum control protocols that generate processes more consistent with time flowing backward than forward. The protocols—techniques ...
Hundreds of Millions of iPhones Can Be Hacked With a New Tool Found in the Wild
A powerful iPhone-hacking technique known as DarkSword has been discovered in use by Russian hackers. It can take over devices running iOS 18 that simply visit infected websites.
Scientists Unveil Cheaper and Faster Way To Extract Lithium From Massive Untouched Reserves
A new solvent-based technique could change how lithium is extracted from brines, potentially making the process faster, cheaper, and viable in places where conventional methods fail. Few elements are as key to the clean energy transition as lithium, and global demand for it is soaring. The metal
A smartphone app can help men last longer in bed
In a randomised trial, men who experience premature ejaculation benefitted from using an app to learn techniques for extending intercourse
Entertainment this week: Pride Weekend at Northstar, Magoo and more!
Friday, March 13 RGXC Masters Weekly Friday Training Groups 9-11 a.m. | Royal Gorge Cross Country, Soda Springs. Join us for our Weekly Master’s Groups! On Friday’s we host our Technique Group, focused on develop...
Nine tips to help you cope during turbulent times
Nine science-backed techniques to help you cope and find some calm in turbulent times.
Why Trump can’t explain the start — or the endgame — of the war in Iran
President Donald Trump has spent a lifetime talking himself out of tough spots. But in the war with Iran, his trusty technique of sowing confusion to postpone reckonings is beginning to fail.
Enormous 3D map of the universe shows brilliant 'sea of light' near the cosmic dawn
A unique technique allowed astronomers to see the early universe as a "sea of light" and explore the effects of gravity and dark energy on cosmic evolution.
March 6, 2026
Astronomer and Queen guitarist Brian May teams up with astrophysicist Derek Ward-Thompson to bring the cosmos to 3D. Plus, Frances Arnold’s game-changing technique of “directed evolution” creates enzymes with unusual capabilities. And, how did we come to think of society's toughest problems as something for individuals to manage rather than governments to regulate?
Scientists build a “periodic table” for AI
Choosing the right method for multimodal AI—systems that combine text, images, and more—has long been trial and error. Emory physicists created a unifying mathematical framework that shows many AI techniques rely on the same core idea: compress data while preserving what’s most predictive. Their “control knob” approach helps researchers design better algorithms, use less data, and avoid wasted computing power. The team believes it could pave the way for more accurate, efficient, and environmentally friendly AI.
A Possible US Government iPhone-Hacking Toolkit Is Now in the Hands of Foreign Spies and Criminals
A highly sophisticated set of iPhone hijacking techniques has likely infected tens of thousands of phones or more. Clues suggest it was originally built for the US government.
What is ‘Jeffing’? This walk-run technique can help you get in shape.
The cardio workout offers significant health benefits, even for those who don’t want to run continuously.
PRESS RELEASE: State Water Contractors release annual science Report
Report shares updates on six studies funded by SWC’s Science Program designed to guide California water management techniques to protect fish and wildlife Press release from the State Water Contractors Today, the State Water Contractors (SWC) released its Annual Science Report for the 2024-25 fiscal year. The report provides updates on six studies, initially funded by more than $4 million from SWC’s Science Program in 2023, designed to generate actionable science that supports fish and habitat protection while maintaining a sustainable water […]
Microsoft can now store data for 10,000 years on everyday glass thanks to laser breakthrough
Improvements to the data writing and reading techniques, alongside a new way to store data, mean the technology is more accessible than before.
Microsoft can now store data for 10,000 years on everyday glass thanks to laser breakthrough
Improvements to the data writing and reading techniques, alongside a new way to store data, mean the technology is more accessible than before.
Five Berkeley Lab Scientists Receive DOE Early Career Research Awards
Five scientists from Lawrence Berkeley National Laboratory (Berkeley Lab) have received Early Career Research Program (ECRP) awards from the Department of Energy. The ECRP program, now in its 16th year, was established to bolster the nation’s scientific workforce by supporting exceptional researchers at the outset of their careers, when many scientists do their most formative work. Recipients use the funding to pursue projects that have the potential to solve scientific challenges and advance the country’s STEM capabilities. To be eligible for the program, a researcher must be an untenured, tenure-track assistant or associate professor at a U.S. academic institution, or a full-time employee at a DOE national laboratory or Office of Science user facility, who is within 10 years of having earned their doctorate. Awards to an institution of higher education will be approximately $875,000 over five years, and awards to a DOE national laboratory or Office of Science user facility will be approximately $2,750,000 over five years. This year’s Berkeley Lab awardees and their projects are listed below: Timon Heim: Better detectors for more powerful particle colliders Timon Heim is a staff scientist in the Physics Division. His ECRP project will develop a new type of detector that can track the particles generated by collisions in particle colliders with high spatial and temporal resolution. Current detectors in use at high-energy colliders, like the ATLAS detector at the Large Hadron Collider (LHC) at CERN, can track the trajectory and measure momentum of particles, but they can’t track a particle’s time of arrival with sufficient precision to discern from which of the many particle interactions they originate. Heim’s proposed technology — called a 4D tracking detector, because it captures data about particles’ positions in space and time — aims to solve this challenge, allowing researchers to glean more precise data from collision experiments to uncover new insights into fundamental forces and potentially discover new particles. The enhanced capabilities of 4D detectors will be a necessity for experiments at future colliders, such as the Muon Collider or Future Circular Collider. The project will develop custom microelectronics that process the signal of a pixelated silicon sensor that can register charged particles passing through it in an extreme radiation environment that these colliders produce during operation. The goal is to measure individual particles’ position with 50-micro-meter spatial and 50 pico-second (one trillionth of a second) temporal precision, for an incoming flux of around 1 billion particles per second per square centimeter. Harrison Lisabeth: Studying underground processes to unleash abundant energy Harrison Lisabeth is a research scientist in the Energy Geoscience Division focused on combining real-world experiments and AI to guide development of geothermal energy systems. His project will explore how deep underground rock formations – where geothermal wells are dug – are stressed by chemical reactions of the minerals and mechanical strain from movements in the Earth. A better understanding of subsurface stresses is essential to engineer safe and reliable geothermal wells that access the heat of deep rocks to produce electricity. It is estimated that the U.S. could generate ten times the amount of energy needed to power the grid using geothermal sources. Lisabeth plans to simulate how minerals grow, dissolve, and influence the behavior of surrounding rock in geothermal reservoirs by tracking chemical changes in rock samples under pressure in the lab. The project will also develop machine learning models to predict geologic strain based on field measurements and refine existing models that describe how common rock types deform under stress. Combining these approaches, Lisabeth hopes to develop a framework to predict stress to improve stability and longevity of geothermal wells. Daniel Carney: Pushing the quantum boundaries of particle measurement Daniel Carney is a staff scientist in the Physics Division who uses quantum information science to study particle physics and gravity. At very small scales, “quantum noise” — random fluctuations from the act of measurement — can drown out faint signals from rare processes. Carney’s ECRP project, “Fundamental Physics at the Quantum Limits of Measurement,” aims to build a new mechanical quantum sensor that can measure extremely small particle interactions below the limits of that quantum noise. The approach uses lasers to hold a tiny bead containing radioactive atoms; when one decays, the system measures the bead’s motion and the energy of any particles emitted. The experiment’s initial goal is to search for heavy sterile neutrinos, hypothetical particles predicted by some extensions of the Standard Model. The system could also help measure the mass of the neutrino, study the way particles interact through the electromagnetic and weak forces, and hunt for low-mass dark matter — all unsolved mysteries in particle physics. Callum Wilkinson: Using machine learning to demystify neutrinos Callum Wilkinson is a staff scientist in the Physics Division and part of the international Deep Underground Neutrino Experiment (DUNE) hosted by Fermi National Accelerator Laboratory. DUNE will create an intense beam of neutrinos that interact in detectors in Illinois and, after an 800-mile journey through the earth, in massive detectors in South Dakota. By precisely measuring neutrinos and how they change, researchers will get a better understanding of their fundamental properties and whether they are responsible for why there is so much more matter than antimatter in our universe. Wilkinson’s ECRP project will apply two machine learning techniques to improve the analysis of DUNE’s data and enhance the experiment’s precision. One approach will look for hidden patterns in how neutrinos interact and produce low-energy particles, while the other will help correct for distortions in what the detectors record. The methods will be tested on one of DUNE’s prototype detectors and could be used in other neutrino experiments, improving their measurements and helping scientists build better models. Aditi Krishnapriyan: Machine learning methods that scale as datasets grow Aditi Krishnapriyan is a faculty scientist in Berkeley Lab’s Applied Mathematics and Computational Research Division (AMCR) and assistant professor at UC Berkeley. Her project, awarded through UC Berkeley, will develop machine learning methods that scale with dataset size for modeling complex, multi-scale phenomena. The resulting tools can be applied in a wide range of research, including the study of new electrolytes for batteries or the examination of molecular interactions. ### Lawrence Berkeley National Laboratory (Berkeley Lab) is committed to groundbreaking research focused on discovery science and solutions for abundant and reliable energy supplies. The lab’s expertise spans materials, chemistry, physics, biology, earth and environmental science, mathematics, and computing. Researchers from around the world rely on the lab’s world-class scientific facilities for their own pioneering research. Founded in 1931 on the belief that the biggest problems are best addressed by teams, Berkeley Lab and its scientists have been recognized with 17 Nobel Prizes. Berkeley Lab is a multiprogram national laboratory managed by the University of California for the U.S. Department of Energy’s Office of Science. DOE’s Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit energy.gov/science.
Holographic 3D printing breakthrough produces objects in less than a second
The technique is called Digital Incoherent Synthesis of Holographic light fields (DISH). Instead of assembling materials layer by layer, DISH projects a three-dimensional holographic light field directly...
Scientists confirm one-dimensional electron behavior in phosphorus chains
For the first time, researchers have shown that self-assembled phosphorus chains can host genuinely one-dimensional electron behavior. Using advanced imaging and spectroscopy techniques, they separated the signals from chains aligned in different directions to reveal their true nature. The findings suggest that squeezing the chains closer together could trigger a dramatic shift from semiconductor to metal. That means simply adjusting density could unlock entirely new electronic states.
Attackers prompted Gemini over 100,000 times while trying to clone it, Google says
Distillation technique lets copycats mimic Gemini at a fraction of the development cost.
Madison Ballet defies convention with shoulder rolls and combat boots
The ballet’s Feb. 13-15 program, ‘Re: Focus: Pointes of View’ in Overture Center, spotlights traditional techniques in nontraditional (and playful) ways.
Scientists take first look inside one of world’s most extreme engines
Scientists used optical diagnostic techniques to 'see inside' solid-fuel ramjets, one of the most extreme engines in the world.
4 Incredible Techniques Combine to Advance Dark Energy Science
Big, recent investments are paying off as the world's dark energy observatories continue to produce results.
‘Phoenix heat melts ICE’: Zipps Sports Grill Bar raids raise questions
Although the Department of Justice said it was not an official immigration action, Raul Piña, who serves on the Community Advisory Board for the Melendres v. MCSO case about racial profiling, disagreed. Piña said this technique of detaining undocumented immigrants was pioneered by former Maricopa County Sheriff Joe Arpaio.
AI Unlocks Hundreds of Cosmic Anomalies in Hubble Archive
Astronomers used a cutting-edge, AI-assisted technique to uncover rare astronomical phenomena within archived data from Hubble.
Distant entangled atoms acting as one sensor deliver stunning precision
Researchers have demonstrated that quantum entanglement can link atoms across space to improve measurement accuracy. By splitting an entangled group of atoms into separate clouds, they were able to measure electromagnetic fields more precisely than before. The technique takes advantage of quantum connections acting at a distance. It could enhance tools such as atomic clocks and gravity sensors.
China-US team’s feat could ‘open entirely new avenues’ in semiconductors
Paper outlines novel ‘self-etching’ technique enabling world’s first fabrication of intricate structures in 2D perovskite materials.
Scientists twist tiny crystals to control electricity
Researchers have developed a technique that allows them to carve complex three dimensional nanodevices directly from single crystals. To demonstrate its power, they sculpted microscopic helices from a magnetic material and found that the structures behave like switchable diodes. Electric current prefers one direction, but the effect can be flipped by changing the magnetization or the twist of the helix. The findings show that geometry itself can be used as a tool for electronic design.
Science teachers from Queensland Open Brethren schools told to teach students about vegetarian dinosaurs on Noah’s Ark
Teachers who attended ‘compulsory’ creationist conference run by US-based fundamentalist group told radiometric dating techniques were flawed
Shoveling snow could pose dangerous health risk for one group, experts warn
Snow shoveling creates hidden heart strain similar to cardiac stress tests. Learn safer techniques and warning signs to protect your cardiovascular health.
'I've Never Seen It in Games Before' — Fable Will Use a Storytelling Technique Borrowed From The Office
Remember those mockumentary-style interview sections in the original reveal trailer for Fable? Well, those will actually be in the game, and they’re inspired by an unlikely source — The Office.
Forensic science meets ancient art—inside the quest for Leonardo da Vinci’s DNA
Researchers are using cutting‑edge DNA techniques to hunt for genetic evidence in centuries‑old artworks in an effort to better understand the genius of Leonardo da Vinci
Chicopee business seized by state over tax delinquency
Sign Techniques fabricated and installed signs for many local businesses.
Scientists destroy 99% of cancer cells in the lab using “vibrating molecules” - Futura-Sciences
A groundbreaking advance in the fight against cancer has just been made. Scientists have developed a revolutionary technique that uses vibrating molecules to kill malignant cells. This innovative method showed a remarkable 99 percent success ... Read more
Positive thinking could boost immune response to vaccines, say scientists
Study suggests being optimistic produces more antibodies, hinting at future healthcare potential of mental techniques