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Scientists turn probiotic bacteria into tumor-hunting cancer killers
Scientists have engineered probiotic bacteria to act as tumor-seeking drug factories. In mice, these bacteria infiltrated tumors and produced a cancer-fighting drug right where it was needed. This targeted approach could make treatments more effective and reduce side effects. More research is needed before it can be tested in people.
Cue Biopharma Reports Fourth Quarter and Full Year 2025 Financial Results and Business Highlights
Advanced research and development of CUE-401 for IND (Investigational New Drug) readiness –CUE-401 is the Company’s lead asset for the treatment of autoimmune and inflammatory diseasesAppointed industry veteran Lucinda Warren as Chief Financial and Business OfficerRaised net proceeds of $10.2M through an underwritten public offeringAnnounced strategic collaboration and license agreement with ImmunoScape to develop breakthrough cell therapy approach for solid tumors – Entitled to receive upfront
Scientists find a new therapeutic target present on up to half of all tumors
For five decades, scientists have known about a notorious cancer-causing enzyme called SRC. But they always assumed it only appeared on the inside of cells, where it sent signals that fueled tumor growth ...
Scientists discover molecule that stops aggressive breast cancer in its tracks
Scientists at Oregon Health & Science University have developed a new molecule that could open the door to treating triple-negative breast cancer, one of the most aggressive and difficult-to-treat forms of the disease. The compound, called SU212, targets and disables a key enzyme that cancer cells rely on to fuel their growth. In tests using humanized mouse models, the molecule caused tumors to shrink and slowed the spread of cancer by forcing the enzyme to break down.
More than 200 lawsuits filed against Kettering Health Network following breach
“I think I’m gradually heading towards remission, even though I am probably not a candidate to have the tumors removed.”
Scientists reveal why a popular anti-aging compound may also fuel cancer
Polyamines—natural molecules found in every living cell—have become stars in the longevity world for their ability to boost cellular cleanup and support healthy aging. But there’s a dark twist: high levels of these same molecules are consistently seen in cancer, where tumors grow aggressively.
New iron nanomaterial wipes out cancer cells without harming healthy tissue
Scientists at Oregon State University have engineered a powerful new nanomaterial that zeroes in on cancer cells and destroys them from the inside out. Designed to exploit cancer’s unique chemistry—its acidity and high hydrogen peroxide levels—the tiny iron-based structure sparks not one but two intense chemical reactions, flooding tumors with cell-damaging oxygen molecules. This dual attack overwhelms cancer cells with oxidative stress while sparing healthy tissue.
New iron nanomaterial wipes out cancer cells without harming healthy tissue
Scientists at Oregon State University have engineered a powerful new nanomaterial that zeroes in on cancer cells and destroys them from the inside out. Designed to exploit cancer’s unique chemistry—its acidity and high hydrogen peroxide levels—the tiny iron-based structure sparks not one but two intense chemical reactions, flooding tumors with cell-damaging oxygen molecules. This dual attack overwhelms cancer cells with oxidative stress while sparing healthy tissue.
Entertainment This Week with Mike Marra
Airdate: February 25th, 2026 Willbee Transit Mix Previews HBAJ Home & Garden ShowFebruary 25, 2026Chamber Announces Women’s Week Panel Discussion BreakfastFebruary 25, 2026Henry Ford Wellness Wednesday: Cancer Screening with Tumor Board Director Donna Long, RNFebruary 25, 2026Jackson Fire Department Offering Free Smoke AlarmsFebruary 25, 2026Entertainment This Week with Mike MarraFebruary 25, 2026New Downtown Parking Plan…
Scientists engineer bacteria to eat cancer tumors from the inside out
Researchers are engineering bacteria to invade tumors and consume them from the inside. Because tumor cores lack oxygen, they’re the perfect breeding ground for these microbes. The team added a genetic tweak that helps the bacteria survive longer near oxygen-exposed edges — but only once enough of them are present to trigger the change. It’s a carefully programmed biological attack that could one day offer a new way to destroy cancer.
Microplastics found in prostate tumors in small study
Plastic particles were found at higher levels in tumor tissue than nearby noncancerous tissue, raising questions about the role they may play in tumor development.
Vanderbilt Health patient receives tumor-infiltrating lymphocyte therapy
The highly personalized treatment is currently approved for patients with advanced stages of melanoma whose tumors have grown despite immunotherapies and/or targeted therapies.
Mysterious RNA led scientists to a hidden layer of cancer
A mysterious RNA found in breast cancer led scientists to uncover an entire hidden class of cancer-specific RNAs across dozens of tumor types. These molecules form unique molecular signatures that identify cancer type and subtype with remarkable accuracy. Some even drive tumor growth and metastasis. Because many are released into the bloodstream, a simple blood test can track how patients respond to treatment and predict survival.
Scientists discover the enzyme that lets cancer rapidly rewire its DNA
Researchers have uncovered the enzyme behind chromothripsis, a chaotic chromosome-shattering event seen in about one in four cancers. The enzyme, N4BP2, breaks apart DNA trapped in tiny cellular structures, unleashing a burst of genetic changes that can help tumors rapidly adapt and resist therapy. Blocking the enzyme dramatically reduced this genomic destruction in cancer cells.
Scientists find nerves actively fuel pancreatic cancer
Scientists have uncovered a hidden partnership between pancreatic cancer and the nervous system. Support cells in the pancreas lure nerve fibers, which then release signals that accelerate early cancer growth. This creates a self-sustaining loop that helps tumors take hold. Blocking the nerve activity significantly reduced tumor growth in experiments, suggesting a new treatment strategy.
Scientists test “smart” nanotech to target cancer tumors with more precision
UC Davis scientists are researching “smart” nanoparticles that anchor to tumors and enable on‑demand delivery of cancer‑fighting therapies, boosting precision while protecting healthy tissue.
Vanderbilt Health celebrates milestone for novel histotripsy procedure
Vanderbilt Health recently performed its 100th histotripsy, a noninvasive procedure in which highly focused ultrasound waves are directed at liver tumors to destroy cancer without ever making an incision.
Cancer vaccine shows promise against HPV-related throat tumors in early study
If proven effective in humans, the vaccine could complement standard therapies for HPV-driven cancer, as well as inform the design of therapeutic vaccines for other diseases.
When immune cells stop fighting cancer and start helping it
Scientists have uncovered a surprising way tumors turn the immune system to their advantage. Researchers at the University of Geneva found that neutrophils—normally frontline defenders against infection—can be reprogrammed inside tumors to fuel cancer growth instead. Once exposed to the tumor environment, these immune cells begin producing a molecule called CCL3 that actively promotes tumor progression.
Why colorectal cancer breaks the immune system’s rules
Colorectal cancer has long baffled scientists because, unlike most tumors, patients often do better when their cancers are packed with immune-suppressing regulatory T cells. New research finally explains why. Scientists discovered that these T cells aren’t all the same: one subtype actually helps keep tumors in check, while another shields cancer from immune attack. The balance between these “good” and “bad” cells can determine whether a tumor grows or shrinks.
A surgeon performed the world's first remote robotic brain surgery
Dr. Homoud Aldahash sat three meters away from his patient as he removed a brain tumor via a robot.
1 of 4 in the US for Advanced Brain, Spine Tumor Diagnostics
UConn Health, JAX partner to offer methylome profiling, enabling precision treatment
New triple-drug treatment stops pancreatic cancer in its tracks, a mouse study finds
By targeting three key growth pathways at once, researchers eliminated pancreatic tumors in multiple mouse models and prevented the cancer from returning, a promising step toward overcoming treatment resistance.
A 20-year-old cancer vaccine may hold the key to long-term survival
Two decades after a breast cancer vaccine trial, every participant is still alive—an astonishing result for metastatic disease. Scientists found their immune systems retained long-lasting memory cells primed to recognize cancer. By enhancing a key immune signal called CD27, researchers dramatically improved tumor elimination in lab studies. The findings suggest cancer vaccines may have been missing a crucial ingredient all along.
Scientists turn tumor immune cells into cancer killers
Scientists at KAIST have found a way to turn a tumor’s own immune cells into powerful cancer fighters—right inside the body. Tumors are packed with macrophages, immune cells that should attack cancer but are usually silenced by the tumor environment. By injecting a specially designed drug directly into tumors, researchers were able to “reprogram” these dormant cells to recognize and destroy cancer.
Lab-grown organoids reveal how glioblastoma outsmarts treatment
Tumor organoid models offer new insight into how the brain and immune system shape cancer behavior.
A common painkiller may be quietly changing cancer risk
Ibuprofen may be doing more than easing aches and pains—it could also help reduce the risk of some cancers. Studies have linked regular use to lower rates of endometrial and bowel cancer, likely because the drug dampens inflammation that fuels tumor growth. Researchers have even found it can interfere with genes cancer cells rely on to survive. Still, experts warn that long-term use carries risks and shouldn’t replace proven prevention strategies.
Scientists Found a Way to Supercharge the Immune System Against Cancer
Researchers have developed a new class of antibodies that amplify the immune system’s ability to fight cancer. By clustering immune receptors that normally receive weak signals from tumors, these four-pronged antibodies push T cells into full attack mode. In early studies, they outperformed conventional antibodies at activating cancer-killing immune cells. The work opens the door to more effective immunotherapy treatments.
Tennessee QB Joey Aguilar has surgery to remove tumor from arm, per report
Aguilar threw for 3,565 yards this season, the third-most in the SEC
MIT study shows high-fat diets give liver cancer a dangerous head start
A high-fat diet does more than overload the liver with fat. New research from MIT shows that prolonged exposure to fatty foods can push liver cells into a survival mode that quietly raises the risk of cancer. Faced with ongoing metabolic stress, these cells abandon their normal roles and revert to a more primitive state that helps them endure harsh conditions. Over time, that shift leaves the liver less functional and far more vulnerable to tumor formation, helping explain why fatty liver disease so often precedes liver cancer.
MIT scientists strip cancer of its sugar shield
Scientists at MIT and Stanford have unveiled a promising new way to help the immune system recognize and attack cancer cells more effectively. Their strategy targets a hidden “off switch” that tumors use to stay invisible to immune defenses—special sugar molecules on the cancer cell surface that suppress immune activity. Early tests show it can supercharge immune responses and outperform current antibody therapies.
Marco Donia: The Science of Tumor-Infiltrating Lymphocytes
Marco Donia: The Science of Tumor-Infiltrating Lymphocytes / Ajay V. Maker, Alena Gros, Alexandre Harari, Brian R Gastman, cancer, Fumito Ito, George Coukos,
Science & Medicine: A breakthrough for glioblastoma patients that may lengthen lives
A new technique for delivering radiation to glioblastoma brain tumors may allow doctors to use much higher doses while preserving healthy brain tissue. UT Health San Antonio's Andrew Brenner, MD, PhD, says this may give patients more time.
December 12, 2025
Over the past century, most cancer research has focused on the tumor itself. Rakesh Jain focused on the tumor’s environment instead. Plus, a glacier’s edge can be a dangerous place to do research. One team is using robots and sound samples to monitor the melting ice. And, when cases of plague pop up in the US, it can feel straight up medieval. It’s treatable, but how and why does it persist?
Scientists uncover the hidden survival trick that lets cancer bounce back
Scientists discovered that certain cancer cells use a low-level activation of a DNA-dismantling enzyme—normally seen in cell death—to survive treatment. Instead of dying, these “persister cells” leverage this sublethal signal to regrow. Because the mechanism is non-genetic, it appears much earlier than typical resistance mutations. Targeting this enzyme could help stop tumors from returning.