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Luma locks down 15-year, $410M fund for life science investments
Luma Group today announced the final close of its inaugural life sciences venture capital fund, totaling $410 million. The New York-based investment firm has had a grip on life sciences since its founding in 2023. The funds unveiled today, dubbed LumaBio Fund I, include investments that have already been made into more than 10 biotechs. They include the likes of eye disease-focused Character Biosciences, rebranded Belgian biotech Coultreon Biopharma and cellular rejuvenation company Altos Labs. The fund saw early success when one of the companies it co-founded, called Vaccine Company, was picked up by Eli Lilly earlier this year for up to $1.55 billion. The acquisition of the in vivo nanoparticle technology-focused biotech formed part of a trio of vaccine buys for the Big Pharma, which has itself been on a prolonged spending spree in 2026. Luma's fund is structured as a 15-year investment with plans to support groundbreaking science and support companies through key milestones from discovery to commercialization, Luma explained in the release. "We founded Luma Group on the belief that extraordinary science, supported by patient, long-term capital, has the power to improve millions of lives," Joshua Fink, founder and managing member of Luma Group, said in the release. "This fund represents more than capital—it is a commitment to partnering with extraordinary innovators as they translate visionary science into life-changing medicines."
How titanosaurs hatched eggs in cooler climates
Fossil eggshells believed to be from some of the biggest dinosaurs that ever lived have been found in a surprisingly cool climate far from the equator. But those titanosaurs were too big to sit on their eggs. Microscopic evidence shows what they did instead to keep the eggs warm enough to hatch.
Suicide-Related ER Visits In Children Rise, But Many Hospitals Lack Specialized Mental Health Care
By Dennis Thompson HealthDay ReporterWEDNESDAY, Sept. 9, 2026 (HealthDay News) — ER visits by children suffering suicide-related crises jumped before and during the COVID-19 pandemic, a new study says. Emergency department visits among children involving self-harm or suicide rose by 74% between 2016 ...
Fantasy Football Week 1 2026 Start ‘Em Sit ‘Em: Quarterback
Week 1 is finally here, and with it comes the annual gut-check every fantasy manager dreads: trusting your gut on a quarterback you drafted or trusting the matchup staring you in the face right now. The names that dominated August mock drafts don’t always match up with the defenses they’re about to face, and a handful of under-the-radar arms are […] The post Fantasy Football Week 1 2026 Start ‘Em Sit ‘Em: Quarterback appeared first on ClutchPoints.
The Cost of Cutting American Science: How Federal Cuts Diminish Public Health Capacity
Among the federal government’s many responsibilities is the work it does to protect public health. Federal agencies monitor our food supply to ensure safety, conduct research to better understand emerging health threats, provide funding for public health programs in communities and work to detect and respond to disease outbreaks. Americans rely on these efforts every day—in a 2024 online survey, 74% of respondents said that “if the federal government issued safety guidance about food you eat regularly,” they would follow it. Changes to Federal Public Health Capacity The Trump administration’s efforts to reshape the federal government have resulted in significant impacts on our nation’s public health capacity over the past 20 months, affecting the response to health concerns such as measles, Ebola and cyclosporiasis. Agencies with core public health, food safety and disease prevention responsibilities experienced large workforce decreases during the first year of the administration. At the Centers for Disease Control and Prevention, for instance, the workforce in February 2026 was 26.7% smaller than in September 2024 before the start of the Trump administration. The Food and Drug Administration saw a similarly steep decline of 21.6%. Agencies such as the National Institutes of Health, Substance Abuse and Mental Health Services Administration and Food Safety and Inspection Service also experienced large workforce decreases. (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); Changes can also be seen in crucial public health occupations. The number of federal food inspectors, for example, decreased by more than half between September 2024 and February 2026, going from 1,035 to 473. This is the lowest number of food inspectors employed by the federal government since at least 2005. By February 2026, there were also 33.3% fewer federal public health program specialists, whose work includes advising federal funding recipients on public health activities and analyzing the effectiveness of public health programs. Government’s capacity is diminished as employees with specialized knowledge and experience in protecting the public and responding to health risks depart, leaving agencies less prepared to carry out their public health missions. There also have been vacancies in critical high-level leadership positions at public health agencies, most notably at the CDC, which had a permanent Senate-confirmed director for less than a month between January 2025 and early August 2026. Although the CDC has previously been led by acting directors at the start of an administration, the nearly yearlong gap since the departure of the administration’s first permanent director in August 2025 is without precedent. As of August 2026, the FDA is also currently without a Senate-confirmed commissioner following the previous commissioner’s resignation in May 2026. Additionally, public health agencies are experiencing increased politicization of their leadership ranks. In agencies such as the CDC and Food Safety and Inspection Service, the number of individuals in the Senior Executive Service—the most senior career leaders in government—has declined significantly, while at the same time the number of political appointees has reached record levels. (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); At the CDC, for example, the number of career SES decreased 42.9% between December 2024 and February 2026, while the number of non-Senate confirmed political appointees at the agency was six times larger than the agency’s historical average from 2009 and 2024. Knowledgeable career leaders are integral to the ability of public health agencies to carry out their work with scientific integrity and professional judgment, and rapid leadership turnover and increased politicization threaten agencies’ ability to make evidence-based decisions to protect our health. The upheaval and politicization in public health agencies have also negatively affected employee engagement. Strong employee engagement is crucial to the ability of agencies to carry out their mission and successfully provide essential services to the public. In the 2025 Public Service Viewpoint Survey conducted by the Partnership for Public Service, the Department of Health and Human Services—which encompasses major public health agencies such as the CDC and FDA—had an employee engagement and satisfaction score of 20.4 out of 100, one of the lowest among large agencies. Only 2.8% of HHS employees indicated trust in their political leaders and only 8.7% reported confidence that they could report a suspected violation of law or regulation without retaliation. Employees at HHS also reported that the agency’s ability to provide services to the public had suffered. Nearly half of employees at HHS, 47.5%, said their work unit was worse at delivering quality services compared to its performance in 2024. In addition, 57.8% said their work unit was performing worse at fulfilling stakeholder needs. In addition to the work done within federal agencies, the federal government also distributes significant funding for public health and disease prevention work to state and local governments, nonprofits and small businesses—funding which has been significantly disrupted. At the CDC, for example, there was a 71.9% decrease in the amount of project grant funding issued in fiscal year 2025 compared to fiscal year 2024. The FDA also issued far less funding in fiscal year 2025—a 21.3% decrease from its fiscal year 2024 funding. Changes in federal funding include the ending of grants to community organizations that worked on HIV prevention and the cancellation of funding for research into improvements to patient safety and healthcare quality. These changes go beyond federal agencies to impact the broader public health ecosystem, including the state and local health departments responsible for much of the on-the-ground public health work in their communities. About 80% of the CDC’s domestic funding is directed towards state and local partners—meaning that cuts to CDC funding can ultimately result in cuts to state and local public health capacity. Federal agencies also provide expertise and assistance to state and local health agencies as they deal with particular health challenges, but workforce cuts have resulted in fewer federal employees available to help. The Impact of Changes to Public Health Capacity These changes to federal public health capacity are not abstract concerns. Disrupted programs, reduced funding and lost expertise at public health agencies across all levels of government threaten the public’s physical well-being and safety. In some cases, this has already led to harm. The most immediate impacts of federal cuts were seen in interruptions to ongoing public health programs and crisis responses. In one instance, when CDC grants were canceled during the 2025 Texas measles outbreak—the most severe measles outbreak in 25 years—public health officials in Lubbock, Texas were forced to pause parts of their measles response work supported by the frozen funding. Lubbock’s director of public health further said that a lack of available CDC experts to reach out to for advice “definitely” impacted the department’s response to the measles crisis. Cuts to federal funding also forced Dallas County Health and Human Services to cut staff and cancel 50 community vaccination clinics during the outbreak. Public health work outside of major outbreak responses was also disrupted. For example, in April 2025, the Milwaukee Public Health Department was unexpectedly unable to reach experts on lead poisoning due to firings at the CDC when responding to concerns about lead contamination in Milwaukee public schools. Due to federal workforce cuts, several programs at the CDC, including Alzheimer’s and epilepsy programs, have also become trapped in limbo—existing on paper, but without the staff necessary to operate. More recent crises reveal how federal cuts have weakened the public health infrastructure needed to prevent and respond to dangerous new outbreaks. Internationally, cuts at the U.S. Agency for International Development eliminated funding for disease testing and contact tracing abroad, which delayed detection of and responses to the 2026 Ebola outbreak in the Democratic Republic of Congo. While international outbreaks may seem far removed, the unchecked spread of disease in any country can quickly pose a danger to economic well-being, security and health around the world. Within the United States, public health cuts inhibited responses to the summer 2026 outbreak of the food-borne parasite cyclospora. At the federal level, cuts to funding for lab equipment and for CDC staff with expertise in parasitic infections—including 9 out of 11 staff members at the lab responsible for identifying parasitic outbreaks in 2025— contributed to the largest reporting delay in outbreak cases at the CDC in 15 years. Conflicting communications from the FDA about the source of the outbreak, which followed cuts to the agency’s communications department, additionally led to confusion among the public about how to best avoid infection. At the same time, cuts to HHS funding and support for local and state public health slowed some health departments’ responses to the crisis. The exact costs of these delays, constraints and confusion in public health responses are difficult to estimate. However, their message is clear: federal cuts have already made containing threats to public health even more of a challenge. Conclusion Protecting public health—from food safety to disease prevention—is one of the federal government’s most important missions. Dramatic and haphazard cuts to federal agencies and funding have already disrupted the public health system, impacting the response to challenges such as measles, lead poisoning and cyclosporiasis. The U.S. public health system needed improvement before these disruptions. Since 2022, federal leadership and coordination in response to public health outbreaks has been on the Government Accountability Office’s High-Risk List of areas in need of attention to improve government effectiveness and efficiency. Recent cuts only compound these concerns. The chaotic dismantling of government and resulting disruptions to crucial functions like public health and disease prevention highlight the need for meaningful reform and concrete policy proposals to reimagine how government can better serve the public and be more effective, responsive and accountable. To learn more about the impact of federal cuts to public health and science more broadly, visit The Cost of Cutting American Science. Learn more For more information on the Partnership for Public Service’s government reform initiative, visit Government for a New Era. View here In line with The Cost of Cutting American Science, federal workforce data in this brief is as of February 2026
The Cost of Cutting American Science: How Federal Cuts Diminish Public Health Capacity
Among the federal government’s many responsibilities is the work it does to protect public health. Federal agencies monitor our food supply to ensure safety, conduct research to better understand emerging health threats, provide funding for public health programs in communities and work to detect and respond to disease outbreaks. Americans rely on these efforts every day—in a 2024 online survey, 74% of respondents said that “if the federal government issued safety guidance about food you eat regularly,” they would follow it. Changes to Federal Public Health Capacity The Trump administration’s efforts to reshape the federal government have resulted in significant impacts on our nation’s public health capacity over the past 20 months, affecting the response to health concerns such as measles, Ebola and cyclosporiasis. Agencies with core public health, food safety and disease prevention responsibilities experienced large workforce decreases during the first year of the administration. At the Centers for Disease Control and Prevention, for instance, the workforce in February 2026 was 26.7% smaller than in September 2024 before the start of the Trump administration. The Food and Drug Administration saw a similarly steep decline of 21.6%. Agencies such as the National Institutes of Health, Substance Abuse and Mental Health Services Administration and Food Safety and Inspection Service also experienced large workforce decreases. (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); Changes can also be seen in crucial public health occupations. The number of federal food inspectors, for example, decreased by more than half between September 2024 and February 2026, going from 1,035 to 473. This is the lowest number of food inspectors employed by the federal government since at least 2005. By February 2026, there were also 33.3% fewer federal public health program specialists, whose work includes advising federal funding recipients on public health activities and analyzing the effectiveness of public health programs. Government’s capacity is diminished as employees with specialized knowledge and experience in protecting the public and responding to health risks depart, leaving agencies less prepared to carry out their public health missions. There also have been vacancies in critical high-level leadership positions at public health agencies, most notably at the CDC, which had a permanent Senate-confirmed director for less than a month between January 2025 and early August 2026. Although the CDC has previously been led by acting directors at the start of an administration, the nearly yearlong gap since the departure of the administration’s first permanent director in August 2025 is without precedent. As of August 2026, the FDA is also currently without a Senate-confirmed commissioner following the previous commissioner’s resignation in May 2026. Additionally, public health agencies are experiencing increased politicization of their leadership ranks. In agencies such as the CDC and Food Safety and Inspection Service, the number of individuals in the Senior Executive Service—the most senior career leaders in government—has declined significantly, while at the same time the number of political appointees has reached record levels. (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); At the CDC, for example, the number of career SES decreased 42.9% between December 2024 and February 2026, while the number of non-Senate confirmed political appointees at the agency was six times larger than the agency’s historical average from 2009 and 2024. Knowledgeable career leaders are integral to the ability of public health agencies to carry out their work with scientific integrity and professional judgment, and rapid leadership turnover and increased politicization threaten agencies’ ability to make evidence-based decisions to protect our health. The upheaval and politicization in public health agencies have also negatively affected employee engagement. Strong employee engagement is crucial to the ability of agencies to carry out their mission and successfully provide essential services to the public. In the 2025 Public Service Viewpoint Survey conducted by the Partnership for Public Service, the Department of Health and Human Services—which encompasses major public health agencies such as the CDC and FDA—had an employee engagement and satisfaction score of 20.4 out of 100, one of the lowest among large agencies. Only 2.8% of HHS employees indicated trust in their political leaders and only 8.7% reported confidence that they could report a suspected violation of law or regulation without retaliation. Employees at HHS also reported that the agency’s ability to provide services to the public had suffered. Nearly half of employees at HHS, 47.5%, said their work unit was worse at delivering quality services compared to its performance in 2024. In addition, 57.8% said their work unit was performing worse at fulfilling stakeholder needs. In addition to the work done within federal agencies, the federal government also distributes significant funding for public health and disease prevention work to state and local governments, nonprofits and small businesses—funding which has been significantly disrupted. At the CDC, for example, there was a 71.9% decrease in the amount of project grant funding issued in fiscal year 2025 compared to fiscal year 2024. The FDA also issued far less funding in fiscal year 2025—a 21.3% decrease from its fiscal year 2024 funding. Changes in federal funding include the ending of grants to community organizations that worked on HIV prevention and the cancellation of funding for research into improvements to patient safety and healthcare quality. These changes go beyond federal agencies to impact the broader public health ecosystem, including the state and local health departments responsible for much of the on-the-ground public health work in their communities. About 80% of the CDC’s domestic funding is directed towards state and local partners—meaning that cuts to CDC funding can ultimately result in cuts to state and local public health capacity. Federal agencies also provide expertise and assistance to state and local health agencies as they deal with particular health challenges, but workforce cuts have resulted in fewer federal employees available to help. The Impact of Changes to Public Health Capacity These changes to federal public health capacity are not abstract concerns. Disrupted programs, reduced funding and lost expertise at public health agencies across all levels of government threaten the public’s physical well-being and safety. In some cases, this has already led to harm. The most immediate impacts of federal cuts were seen in interruptions to ongoing public health programs and crisis responses. In one instance, when CDC grants were canceled during the 2025 Texas measles outbreak—the most severe measles outbreak in 25 years—public health officials in Lubbock, Texas were forced to pause parts of their measles response work supported by the frozen funding. Lubbock’s director of public health further said that a lack of available CDC experts to reach out to for advice “definitely” impacted the department’s response to the measles crisis. Cuts to federal funding also forced Dallas County Health and Human Services to cut staff and cancel 50 community vaccination clinics during the outbreak. Public health work outside of major outbreak responses was also disrupted. For example, in April 2025, the Milwaukee Public Health Department was unexpectedly unable to reach experts on lead poisoning due to firings at the CDC when responding to concerns about lead contamination in Milwaukee public schools. Due to federal workforce cuts, several programs at the CDC, including Alzheimer’s and epilepsy programs, have also become trapped in limbo—existing on paper, but without the staff necessary to operate. More recent crises reveal how federal cuts have weakened the public health infrastructure needed to prevent and respond to dangerous new outbreaks. Internationally, cuts at the U.S. Agency for International Development eliminated funding for disease testing and contact tracing abroad, which delayed detection of and responses to the 2026 Ebola outbreak in the Democratic Republic of Congo. While international outbreaks may seem far removed, the unchecked spread of disease in any country can quickly pose a danger to economic well-being, security and health around the world. Within the United States, public health cuts inhibited responses to the summer 2026 outbreak of the food-borne parasite cyclospora. At the federal level, cuts to funding for lab equipment and for CDC staff with expertise in parasitic infections—including 9 out of 11 staff members at the lab responsible for identifying parasitic outbreaks in 2025— contributed to the largest reporting delay in outbreak cases at the CDC in 15 years. Conflicting communications from the FDA about the source of the outbreak, which followed cuts to the agency’s communications department, additionally led to confusion among the public about how to best avoid infection. At the same time, cuts to HHS funding and support for local and state public health slowed some health departments’ responses to the crisis. The exact costs of these delays, constraints and confusion in public health responses are difficult to estimate. However, their message is clear: federal cuts have already made containing threats to public health even more of a challenge. Conclusion Protecting public health—from food safety to disease prevention—is one of the federal government’s most important missions. Dramatic and haphazard cuts to federal agencies and funding have already disrupted the public health system, impacting the response to challenges such as measles, lead poisoning and cyclosporiasis. The U.S. public health system needed improvement before these disruptions. Since 2022, federal leadership and coordination in response to public health outbreaks has been on the Government Accountability Office’s High-Risk List of areas in need of attention to improve government effectiveness and efficiency. Recent cuts only compound these concerns. The chaotic dismantling of government and resulting disruptions to crucial functions like public health and disease prevention highlight the need for meaningful reform and concrete policy proposals to reimagine how government can better serve the public and be more effective, responsive and accountable. To learn more about the impact of federal cuts to public health and science more broadly, visit The Cost of Cutting American Science. Learn more For more information on the Partnership for Public Service’s government reform initiative, visit Government for a New Era. View here In line with The Cost of Cutting American Science, federal workforce data in this brief is as of February 2026
Clearway Health Scales Operational Excellence with Appointment of Chief Operating Officer
/PRNewswire/ -- Clearway Health, a company that partners with hospitals and health systems to plan, build and operate specialty pharmacy programs, announces...
September 9 Playbook: “Trumpapalooza”
🏈 It’s a Football Wednesday. The NFL season starts tonight 🎶 Your Morning Pick Me Up. NFL on NBC Sunday Night Theme. Champions United PA Weather🌂 Bradford | Chance of Showers, 81🌤️ Mount Carmel | Partly Sunny, 82☀️ Ambler | Mostly Sunny, 87 PA Sports ⚾ Phillies (81-64, -4.0 GB, +3.5…
Recent Stanton graduate wins Humane Science Award from National Anti-Vivisection Society
Alan Alwakeel, a recent graduate of Stanton College Preparatory School in Jacksonville, Florida, was one of just five recipients of the prestigious Humane Science Award at the 2026 Regeneron International Science and Engineering Fair (ISEF). The award is presented by the National Anti-Vivisection Society (NAVS), a nonprofit devoted to the advancement of science without harming animals and the only animal advocacy group invited to award a prize at the ISEF. Each recipient received a $3,000 prize
Aurora Appoints Seasoned Biopharmaceutical Executive to Lead Commercial Acceleration of Global Medical Cannabis Business
/PRNewswire/ -- Aurora Cannabis Inc. (NASDAQ: ACB) (TSX: ACB), the Canadian-based leading global medical cannabis company, announces Faris El Refaie, a...
Springfield Health Department partners with Big Y for free vaccine clinics
The Springfield Department of Health and Human Services and Big Y Pharmacy have partnered this season to offer vaccine clinics for community members.
Guelph meat science faculty went from five to zero
Federal funding flowed to Protein Industries Canada and plant proteins after 2018 while a $32-billion meat industry went without its share.
Favored Farmhouse expands business
MOSES LAKE — The owners of the Favored Farmhouse celebrated expanding their business by cutting the ribbon for the new drive-through Thursday – and co-owner Daphne Martinez said there’s more to come.
Sept. 9 - Savannah Philharmonic Announces Upcoming Phil the Neighborhoods Series
September 9, 2026 - The Savannah Philharmonic will present their annual Phil the Neighborhoods fall series. This annual concert series brings residents and families together through music.
Scientists and algorithms: Finding the right balance in modern drug development
The future of drug development is not scientists versus algorithms. It is scientists and algorithms working together.
Worried about rising beef prices? WA farmers say, share a cow
CARNATION, Washington — Far from the refrigerated meat sections of Seattle's grocery stores, two dozen beef cattle relaxed in the afternoon drizzle falling on Carnation Farms' grassy fields. Livestock manager
Arsenal XI vs Napoli – Predicted lineup and team news
Arsenal open their Champions League campaign at Napoli on Wednesday, returning to the Stadio Diego Armando Maradona for the first time since their 2019 Europa League quarter-final win there. Mikel Art...
USI drops their second straight match at home
EVANSVILLE, Ind. (WEHT) — The University of Southern Indiana men’s soccer is still looking for their first win under new head coach Mads Kaiser after falling 2-1 to Bellarmine. The loss was their second straight at home after falling to IU Indy last week. The Knights got on the board first in the first half with […]
How Meta’s Billions for Teen Mental Health Can Make a Real Difference
Instead of repeating the mistakes they made with tobacco money, states should set clear goals — and measure outcomes through dashboards accessible to all — for programs addressing social media’s harms to teenagers.
Undefeated Anthony Wint Books Second UFC Fight in 43 Days
Former NFL player Anthony Wint has booked his second UFC fight in 43 days. The undefeated athlete out of Homestead, Florida, fights on the UFC 332 card on October 3 in Salt Lake City, Utah. He takes on promotional newcomer Lucas Armand in the heavyweight division. The UFC announced the fight on the Dana White’s […] The post Undefeated Anthony Wint Books Second UFC Fight in 43 Days appeared first on HEAVY.
Taylor Swift Promoter Tells Judge Live Nationr Could Kill His Business
Louis Messina, tour promoter for Taylor Swift's Eras Tour as well as Ed Sheeran and other top acts, told a judge Live Nation has harmed his business.
Canfield Fair incident puts focus on political rhetoric in Ohio governor’s race
For months, Ohio’s governor’s race has been fought with increasingly personal campaign messages.Now, after an armed man pushed through a crowd toward Democrati
The Trump administration slams Ford for its ties to China
The Trump administration on Tuesday expressed “profound concern” to carmaker Ford about its alleged ties to Chinese technology and manufacturing.
Man accused of assault, inducing panic at Dr. Amy Acton event pleads not guilty
The armed Ohio man investigators said set off a security scare involving Democratic gubernatorial candidate Dr. Amy Acton pleaded not guilty in court Tuesday.
Chris Mason: Burnham looks to show he will go further than Starmer with West Bank sanctions
It is hoped that coordinated action minimises the blowback to any one country from Israel or America, our political editor writes.
Carmignac Gestion Buys Shares of 100,508 Caesars Entertainment, Inc. $CZR
Carmignac Gestion bought a new position in shares of Caesars Entertainment, Inc. (NASDAQ:CZR - Free Report) during the 2nd quarter, according to the company in its most recent 13F filing with the Securities & Exchange Commission. The institutional investor bought 100,508 shares of the company'
Incumbent GOP governor rolls to primary victory after keeping Trump at a distance
Kelly Ayotte cruised past Republican primary challengers, setting up a high-stakes New Hampshire governor's race against Democrat Cinde Warmington.
Shohei Ohtani’s Health Raises New Alarm After One-Game Dodgers Return
Los Angeles Dodgers star Shohei Ohtani is out of the lineup just one day after returning, sparking increased alarm.
'Practical Magic 2' is charming but cursed by repetition
The Owens sisters are as bewitching as ever – multiple generations of them, in fact – in “Practical Magic 2,” even if the sequel might only truly cast a spell
From farm to table: Edgecombe County effort expands access to fresh, healthy food
An Edgecombe County farm is expanding its efforts to tackle food insecurity and improve access to healthy food across eastern North Carolina.
Dallas mayor sounds alarm on the 'grave threat' facing America's cities
Dallas Mayor Eric Johnson warns a socialist movement threatens U.S. cities and the economy, touting his city's financial services growth and free markets.
Allegri counts on European 'motivation and adrenaline' for Napoli
Coach Massimiliano Allegri is hoping the arrival of Champions League football can help put Napoli on the right track after back-to-back defeats in Serie A. Victory on the opening day against Genoa has been undermined by successive defeats at the hands of Como and Inter Milan, leaving new boss Allegri looking for a reset when his side welcome Arsenal to Stadio Diego Armando Maradona on Wednesday evening.
NFL media hires two veterans as new analysts
NFL Media is bolstering its ranks ahead of the 2026 season with a pair of familiar names. The league’s media arm is undergoing a transition this season with NFL Network now under the umbrella of ESPN. That arrangement is part of the equity deal that now sees the league as a minority owner in the…
Armor Health Names Regional VP of Client Relations
National correctional healthcare provider Armor Health has appointed Tamara Taylor, RN, CCHP as the company’s first Regional Vice President of Client Relations.
G.A. Carmichael Family Health Center ribbon cutting set for Wed., Sept. 9
GOODMAN, MS — G.A. Carmichael Family Health Center is proud to announce the grand opening and ribbon cutting of the G.A. Carmichael Community Student Health Center at Holmes Community College…
If AI thinks it's conscious, it's more likely to believe in vampires, karma and ghosts, new study shows. What does it mean for how we use it?
A new study shows that measures to stop AI's claims of consciousness have unintended consequences for non-human entities
What Trump’s new study says about support for trans rights — and why experts are worried
This story was originally reported by Orion Rummler and Jasmine Mithani of The 19th. Meet Orion and Jasmine and read more of their reporting on gender, politics and policy. A new study from the Trump administration is sending alarm bells through pro-democracy groups for its potential to fuel a crackdown on Americans who support LGBTQ+ […]
See Mark Harmon's return as Gibbs in 'NCIS: Origins' trailer
Mark Harmon is back in action as Leroy Jethro Gibbs.
Campbell’s investing to turn around Snacks business
National media campaigns to feature Goldfish and Pepperidge Farm.
No Evidence That Sugar Substitutes Harm Weight, Health, or Sweet Taste Preferences
New review of three major EU-funded trials shows swapping sugar for non-nutritive sweeteners may help with weight loss maintenance, while broader "sweet taste" exposure appears largely neutral for health.
Kenya moves to regularize foreign businesses after president's remarks alarm immigrant communities
The Kenyan government on Tuesday gave foreigners running businesses in the country 90 days to obtain or update required documents, including work permits and business licenses. The move followed rema...
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
SC's Emerging Biotech Industry Receives National Recognition
Genetic Engineering & Biotechnology News (GEN) recently named the Palmetto State among its “Regional and State Clusters to Watch” in its first-ever Next 10 U.S. Biopharma Clusters report, highlighting emerging life sciences ecosystems beyond...
Cleveland Armenian Festival returns to Richmond Heights this weekend
St. Gregory of Narek Armenian Church hosts the annual event Friday evening and all day Saturday.
WIS360 Top Stories for Tuesday, September 8th: Health Alert: Farm Fatality report
Health Alert: Farm Fatality report
It’s harmful for professors to preach their political beliefs
Senior staff writer Abby Breidenbach discusses the need for political discourse in the classroom and why that is harmed when a professor preaches their own beliefs.
It’s harmful for professors to preach their political beliefs
Senior staff writer Abby Breidenbach discusses the need for political discourse in the classroom and why that is harmed when a professor preaches their own beliefs.
Six decades of politics (but little government)
The first aired episode of “Star Trek,” entitled “The Man Trap,” premiered on September 8, 1966 — 60 years ago today. I’m actually editing a political science fiction issue of The Forum right now, and it’s prompted to me think a lot about the ways that Trek deals with politics and government and what it’s offered us as commentary. The @smotus report is a reader-supported publication. To support this work, please become a paid subscriber. Subscribe The original TV series ran from 1966 to 1969. It had a loyal but modest following, but the audience grew substantially with the series in syndication for years after that. The franchise developed its first motion picture in 1979, followed by five sequels, and then a whole other series of films built around the “Next Generation” series that first aired in 1987. In recent decades, several more TV series have built up around it, including the current “Strange New Worlds,” now in its fourth season. Throughout the past six decades, the franchise has offered us a good many insights into US politics and international relations, although often disguised as science fiction yarns. The original series was largely a Cold War fable, with the United Federation of Planets (a stand-in for the US) perpetually at odds with the Klingon Empire (a stand-in for the USSR). The “Let That Be Your Last Battlefield” episode (1969) posited a planet divided into two races, largely indistinguishable to outsiders, but nonetheless constituting a brutal racial hierarchy. “Patterns of Force” (1968) showed a struggling planet where the leader had attempted to construct a benevolent dictatorship — literally Nazism without bigotry — and found that authoritarianism could not exist apart from hierarchy and oppression. (Relatedly, I’d put “Star Trek VI: The Undiscovered Country,” high on a list of dad films about the end of the Cold War, near “The Hunt for Red October.”) Get 20% off for 1 year Indeed, the original series itself was something of a political statement, with a multi-racial crew running the Enterprise, a diverse and largely peaceful Federation mostly free from want and oppression, and protected by Starfleet, an armed force whose scientific mission was at least as important as its military one. Famously, when Nichelle Nichols wanted to walk away from the role of Uhura on the original series, none other than Martin Luther King, Jr. met with her and urged her to remain on the show, discussing the importance of viewers seeing an intelligent Black woman as part of the command team three centuries hence. Later series in the Trek franchise offered a good deal of political commentary on their own, but probably none as explicitly and incisively as “Deep Space Nine,” which ran from 1993 to 1999. The episodes surrounding the Dominion War, especially the “In The Pale Moonlight” (1998), showed the compromises, sacrifices, and moral rot associated with winning even a just war — probably better than any series would until “Andor” (2022-25). In “Far Beyond The Stars” (1998), Captain Benjamin Sisko is somehow transplanted to the role of a science fiction writer in 1950s New York. The writer is frequently sidelined and his ideas stolen because publishers don’t want to credit a Black writer. Several series have depicted the secretive Section 31 — an unacknowledged black ops security force operating within Starfleet. These episodes often end up using Section 31 as a foil to show the dangers of a lawless group within a lawful society, even (especially) when that group posits itself as essential for everyone else’s freedom to continue. The current “Strange New Worlds” has played with a few political themes. I found the first two seasons of this show among the best that the Trek franchise has produced in decades, but this season and the last have really been struggling for ideas. Yet one interesting thread is the idea that the diplomatic and enlightened leadership style of Captain Christopher Pike will not work in all situations. “A Quality of Mercy” (2022), which I wrote about here, puts Pike in the middle of a battle with a Romulan vessel in an alternate timeline, and finds that Pike’s conciliatory style would actually make a lengthy and deadly war more likely, while a quick and more violent approach might have prevented the war. This season’s opener, “Valles Marineris,” shows a pre-lightspeed civilization locked in a war to the death with a neighboring planet. The idea of an alliance or a federation hasn’t even occurred to them — their ship’s commander is curious but doesn’t see it as an option. For a franchise as political as “Star Trek,” one thing we almost never see is the government. We get occasional glimpses of Starfleet’s council — mostly uniformed people at a rectangular table — but almost no sense of how the Federation is governed. Are there elections? Who is in the legislature? How much power does the president have? What kind of factional divisions do they wrestle with and how? The shows and films are pretty silent on this. We’ve seen a few military tribunals within Starfleet, but little about how civilians deal with crime and injustice. With recent years seeing some of the franchise’s more interesting plot lines and casts, it seems clear that Star Trek is still full of energy and ideas. Given the erosion of American democracy and the reshuffling of the international order, there’s no shortage of material for future shows to comment on. I’m not sure we should toast to 60 more years, but cheers to a show that continues to teach us about ourselves. Share
APPLEGATE SHARES NEW FINDINGS ON OMEGA FATTY ACIDS THROUGH REGENERATIVE HEALTH INITIATIVE
/PRNewswire/ -- Applegate Farms, LLC, the maker of the nation's leading natural and organic meat brand, today shared new omega fatty acid findings from its...
Optimi Health to Participate in the H.C. Wainwright 28th Annual Global Investment Conference
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Campbell’s plans to boost Snacks business in 2027
National media campaigns to feature Goldfish and Pepperidge Farm.
Can what we feed farm animals directly benefit our own health?
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NRCC adds 4 Republicans to MAGA Majority program
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Osaka has the science. Now it needs the business
Osaka is striving to turn world-class life sciences research into a global healthcare industry - testing whether Japan's pharma and biotech sector can finally scale internationally.
Osaka has the science. Now it needs the business
Osaka is striving to turn world-class life sciences research into a global healthcare industry - testing whether Japan's pharma and biotech sector can finally scale internationally.
Osaka has the science. Now it needs the business
Osaka is striving to turn world-class life sciences research into a global healthcare industry - testing whether Japan's pharma and biotech sector can finally scale internationally.
Osaka has the science. Now it needs the business
Osaka is striving to turn world-class life sciences research into a global healthcare industry - testing whether Japan's pharma and biotech sector can finally scale internationally.
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GenSight Biologics Provides September 2026 Business Updates
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Phoenix family says call for mental health help ended in deadly police shooting
A Phoenix family says their call to police for help during their son’s mental health crisis ended with him being shot and killed by officers. Phoenix police say 20-year-old Jonathan Marquez Delgado was armed with a knife and ran toward officers. There are different accounts of what happened Sunday morning.
Phoenix family says call for mental health help ended in deadly police shooting
A Phoenix family says their call to police for help during their son’s mental health crisis ended with him being shot and killed by officers. Phoenix police say 20-year-old Jonathan Marquez Delgado was armed with a knife and ran toward officers. There are different accounts of what happened Sunday morning.
4 CDMOs to consider when outsourcing manufacturing
Contract development and manufacturing organizations looking to do business with biopharmas include Lonza, which has more than 30 sites, and Samsung Biologics, which recently announced a planned acquisition of another CDMO.
Small Farms Get Hands-on Focus at Farm Science Review
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Can what we feed farm animals directly benefit our own health? Our research suggests it can
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A British Carmaker Fitted Anti-Lock Brakes to a Road Car in 1966 and All-Wheel Drive 14 Years Before the AMC Eagle. Then It Went Bust, and It Just Came Back With 940 Horsepower
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Mental Health Monday: Self Care
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Michigan politicians spent Monday shaking hands with voters, a day after an armed man charged at an Ohio candidate
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Armed attacker arrested after lunging at Ohio Jewish gubernatorial candidate Amy Acton
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Christian Barmore returns to Patriots practice, TreVeyon Henderson remains out
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Armed Ohio man arrested after charging at Democratic candidate for governor, Amy Acton
The candidate, Amy Acton, was not hurt, but her team said several others were injured as the man tried to "lunge" at her.
Armed man charged toward Democratic candidate for Ohio governor at fair, law enforcement says
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West Valley light rail extension raises business concerns along Indian School Road corridor
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Polanski faces Green rival in his pursuit of Keir Starmer’s old seat
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Ratko Mladić funeral exposes gap between Serbia’s EU ambitions and political reality
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Third time the charm? Democrat Christina Bohannan tries again in pivotal US House race in Iowa
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Germany's AfD won a state election in a landslide, sounding an alarm for centrist politics
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Business Monday: Kaʻū farmers grapple with losses of trees, crops and infrastructure from Hurricane Lala
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Animal Welfare In Shrimp Aquaculture: Science-Based Manual To Foster Sustainable Rearing Practices
Over the past two decades, shrimp aquaculture has grown enormously worldwide. At the same time, consumer awareness of ethical, environmental and sustainability issues has increased, and concern for animal welfare is growing. Consumers are paying closer attention to how farmed animals are treated, pushing retailers and producers to improve standards.
Armed man charged toward Democratic candidate for Ohio governor at fair
He injured several people before he was stopped by troopers