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Live updates: Eagles look to snap 3-game losing skid against Raiders
Follow along for live updates as Jalen Hurts and the Eagles look to snap a three-game losing skid against the Raiders.
Celebrity News | Ella McCay Release + Dick Van Dyke’s Centennial: Revisiting Three Entertainment Giants
James L. Brooks, Dick Van Dyke & Carl Reiner: Three Great Talents
Campbell County health and food inspections (12/5/25–12/11/25)
GILLETTE, Wyo. — The Consumer Health Services Division of the Wyoming Department of Agriculture conducts inspections of retail food establishments throughout Wyoming (where there is not a local health department that does inspections) to help ensure safety of Wyoming residents. Campbell County establishments are inspected at least once a year by the WDA. All of […]
Researchers turned a hamster into a hybrid creature that feeds on light—half animal, half plant - Futura-Sciences
A team from the University of Tokyo has achieved a breakthrough that sounds straight out of science fiction: they’ve created living cells that are part hamster, part plant — and capable of performing photosynthesis. Imagine ... Read more
A grad student’s wild idea triggers a major aging breakthrough
Senescent “zombie” cells are linked to aging and multiple diseases, but spotting them in living tissue has been notoriously difficult. Researchers at Mayo Clinic have now taken an inventive leap by using aptamers—tiny, shape-shifting DNA molecules—to selectively tag these elusive cells. The project began as an offbeat conversation between two graduate students and quickly evolved into a collaborative, cross-lab effort that uncovered aptamers capable of binding to unique surface proteins on senescent cells.
Science & Medicine: A breakthrough for glioblastoma patients that may lengthen lives
A new technique for delivering radiation to glioblastoma brain tumors may allow doctors to use much higher doses while preserving healthy brain tissue. UT Health San Antonio's Andrew Brenner, MD, PhD, says this may give patients more time.
After 3 tech layoffs, I knew I had to lean into being a founder
After going through multiple layoffs as a UX designer, Kelly Withers used her savings to fund her startup, Carmu, which sells yoga mats.
Carman: Hickenlooper owes Colorado voters answers, not threats
The Democratic campaign machine is already mobilizing to crush Julie Gonzales’ bid to unseat Sen. Hickenlooper
Nottingham Forest vs Tottenham Hotspur – Match Preview and Team News
Tottenham Hotspur travel to the City Ground on Sunday afternoon, aiming to secure three consecutive wins in all competitions for the first time under Thomas Frank.They face a Nottingham Forest side lo...
Belfast throws down Ireland's first sumo wrestling club
Belfast-based Sumo Na hÉireann is Ireland's first sumo club, capitalising on the sports growing popularity.
Anti-immigrant rhetoric and policies intensify across Europe
In the past year, tens of thousands hostile to immigrants marched through London chanting “send them home!”
"Grand Pro Circuit" is a new retro open-wheel sim aiming for 1980s realism
A low-poly look, manual gearboxes and no assists meet tyre temps, changeable weather and mechanical failures in this Steam-bound open-wheel throwback
2025 NFL Odds: Best Bets for Ravens-Bengals, Bills-Patriots
Sammy P has three NFL games on his slip this weekend. See how he's betting Ravens-Bengals, Bills-Patriots and Browns-Bears.
Full-length Replay: Jackson State at Northwestern
Northwestern (5-4) tries to put an end to a three-game slide when it hosts Jackson State (1-8).
Denfeld senior talks mental health in mom-daughter podcast
Through a grant from the Ann Bancroft Foundation, Ileini and Ashley Hirt share their journey of navigating mental health via shared podcast.
Packers vs Broncos Props & Best Bets for Week 15
Bo Nix has started throwing more frequently for Denver in recent weeks, and we expect that trend to continue in Sunday’s showdown against Green Bay.
Kai Rogers throws it DOWN with one-hand! 😤
Kai Rogers throws it DOWN with one-hand! 😤
Teen’s video a ‘Breakthrough’ in science communication
Seventeen-year-old Grace Lee from Chula Vista is gaining national attention as a finalist in the global Breakthrough Junior Challenge, an annual competition that invites students to create original videos explaining complex scientific ideas in creative and engaging ways. Founded in 2015, the contest encourages young people to break down advanced scientific theories using imagination and storytelling— “Steven Spielberg meets Albert Einstein,” as organizers describe it. Lee’s submission centers on the principle of least time in physics, a concept that explains why light always travels the path that takes the least amount of time. To bring the idea to life, she used intricate origami characters and stop-motion animation, along with simple at-home experiments, she said. “The fact that light always travels via the path that takes the least amount of time sounds simple at first, but nature is full of surprises,” she said. “This principle is actually very profound and underlies many different fields in physics that seem completely unrelated, from optics to Newton’s laws to Einstein’s theory of relativity.” Also, origami has long been one of her passions and integrating it into her project felt natural. She often makes origami gifts for friends and teaches origami in her school clubs. “A single 10-second scene would take hours to craft,” she said, noting the mixture of stop-motion and post-production editing required to animate expressions and movement. To ensure the science remained accurate and accessible, she spent time reading books and online resources, writing a script, creating a storyboard, and filming and editing repeatedly until the visuals worked.The experiments were among the biggest challenges. To demonstrate water waves, she used everyday household items — “a spatula and an electric toothbrush to vibrate the waves, glass in a baking pan for different depths, and an iPhone flashlight so the waves would be visible.” She also put careful thought into explaining the principle through analogies, including a gingerbread man and a fox. “Analogies and visuals are incredibly important,” she said. “Visual demonstrations allow viewers to see how the science actually works.” Beyond the competition, Lee is deeply involved in science leadership and advocacy. She serves as International President of miRcore, the world’s largest student computational biology organization, with 136 chapters across five countries. She leads a 20-member executive board, organizes outreach connecting schools worldwide, and has helped run workshops at locations including Scripps Research Institute and the University of Michigan. “I used to be intimidated,” she said, but she gradually grew her skills and confidence. “Now I am no longer afraid to use my voice and enthusiasm to bring out the best in others.” Her research experience includes two peer-reviewed papers on asthma and vaping. Misconceptions around vaping, she said, show why clear science communication matters. “Our research shows that there is long-term harm to your lungs on the cellular level that isn’t obvious unless you come down with an illness like the flu,” she said. Lee also founded Full Hearts at Eastlake High School, transforming the small club into one of the school’s largest, with hands-on service projects in partnership with local nonprofits. She continues mentoring younger students to sustain the mission. If she wins the Breakthrough Junior Challenge, Grace hopes the $100,000 science lab prize for her school will expand opportunities for students who have limited access to equipment and hands-on science outside the classroom.
Higher cost, worse coverage: Affordable Care Act enrollees say expiring subsidies will hit them hard
Americans are feeling the strain already with less than three weeks to go until the expiration of COVID-era tax credits that have helped many people pay for health insurance through the Affordable Care Act.
Business notes: Tommy’s Dutch Lunch reopens following renovations
The restaurant is open from 7 a.m. to 1 p.m., Tuesday through Sunday at 1203 W. Pine St.
Trump moves on D.C. golf courses with a default notice to nonprofit
The administration puts the National Links Trust on the clock in a bid to take control of the city’s three public golf courses.
Today is Dick Van Dyke’s 100th birthday: His tips for a long, healthy life—'sometimes I feel like I'm 15 again'
Dick Van Dyke is officially a centenarian! Here are three research-backed staples in his routine that he credits for his 100 years of life.
Trump attacks on political opponents spur a surge of threats, NBC News review finds
In recent weeks, nearly two dozen elected officials on both sides of the aisle said they were targeted after getting caught in the president's crosshairs.
Arts and entertainment throughout the region
A listing of local arts and entertainment events.
‘We are more successful than they wanted us to be’: Chloe Kelly on team squabbles, scoring that penalty and surviving sport’s gender wars
Women’s football is booming – but the bigger it’s got, the messier it’s become for players. Through it all, the hot tip for Sports Personality of the Year has kept a cool head
EXCLUSIVE: Inside Trump’s private schedule as media fixates on his health
Fox News obtained President Donald Trump's December schedule revealing back-to-back meetings and calls extending into evening hours throughout the month.
Game thread: St. John’s men’s basketball vs. Iona
The Red Storm take on Rick Pitino’s former team in a Saturday matinee at the Garden
Enquirer names Cincinnati high school athletes of the week, Dec. 12
Cincinnati.com readers selected the Beacon Orthopaedics & Sports Medicine's Athletes of the Week from high school sports action through Dec. 7.
Speaker Johnson unveils health care plan as divided Republicans scramble for alternative
The legislation, unveiled Friday, is a last-minute sprint as Johnson's party refuses to extend the enhanced tax subsidies for those who buy policies through the Affordable Care Act.
Global Space Award winners 2025: Playmakers, innovators, and science breakthroughs
The inaugural ceremony was held at London's Natural History Museum on Dec. 5.
Why one trauma doctor sees self-driving cars as a 'public health breakthrough'
NPR's Ailsa Chang speaks to Dr. Jonathan Slotkin about the new data released by Waymo about accidents and their self-driving cars.
Why redistricting fell flat in Indiana: From the Politics Desk
Plus, three questions ahead of our new poll this weekend.
Roundup: Indiana rejects redistricting, Trump bashes immigrants in Pennsylvania : The NPR Politics Podcast
It’s been a busy week in the political world. We discuss the Indiana state Senate's rejection of President Trump's push to redraw the state’s congressional districts, President Trump's speech on the economy in Pennsylvania in which he denigrated immigrants, and the United States' seizure of an oil tanker off the coast of Venezuela.This episode: political correspondent Sarah McCammon, senior White House correspondent Tamara Keith, and senior political editor and correspondent Domenico Montanaro.This podcast was produced by Casey Morell and Bria Suggs, and edited by Rachel Baye.Our executive producer is Muthoni Muturi.Listen to every episode of the NPR Politics Podcast sponsor-free, unlock access to bonus episodes with more from the NPR Politics team, and support public media when you sign up for The NPR Politics Podcast+ at plus.npr.org/politics.Please let us know what you think of our show and how we can make it better by filling out this quick survey. As a token of our appreciation, three respondents will be randomly selected to receive a $25 gift card.
Steve Adelstein: PFAS water contamination has met its match
PFAS-free drinking water is finally achievable through fast, scalable, lab-verified technology.
NYC Health + Hospitals/Elmhurst Receives $1 Million in Advanced Surgical Microscope Equipment Funded by Queens Borough President Donovan Richards - NYC Health + Hospitals
NYC Health + Hospitals/Elmhurst recently held a ribbon-cutting ceremony to celebrate the acquisition of three new state-of-the-art Leica surgical
Tesla made a $350 pickleball paddle
The paddle follows a long line of oddball products, from $450 mezcal to questionably legal flamethrowers.
Federal DOT threatens to pull highway funds to N.Y. over immigrant CDLs
According to Sean Duffy, 53% of non-domiciled CDLs in New York were issued illegally.
Doctors: Florida plan to repeal vaccine rules a 'direct threat' to health
Florida’s medical community came out in force on Friday at a Department of Health workshop in Panama City on vaccine requirements in Florida.
NYC Health + Hospitals/South Brooklyn Health Recognized for Highest Quality Stroke Care by the Joint Commission - NYC Health + Hospitals
NYC Health + Hospital’s/South Brooklyn Health announced its designation as a Thrombectomy Capable Stroke Center by the Joint Commission. This
Best Missouri sports betting apps: Top MO sportsbook apps to receive $3,000 in bonus offers, promos
Missouri betting apps are now accepting real-money bets, and this page will guide you through the best sports betting apps currently available in Missouri.
NSF announces new initiative to launch and scale a new generation of transformative independent research organizations to advance breakthrough science
The U.S. National Science Foundation Directorate for Technology, Innovation and Partnerships (NSF TIP) on Friday announced the launch of a new initiative designed to launch and scale a new generation…
RFK Jr is a danger to public health – but local Maha laws could be a bigger threat
An array of under-the-radar initiatives are taking hold across the US, often tied to immunization, fluoridation and raw milk
Registration opens for business expo
Registration is open for the University of Lynchburg’s third annual business expo, Building Communities Through Partnerships.
Supporting Breakthrough Health Advancements in Eswatini Under the America First Global Health Strategy - United States Department of State
Today, the United States and the Government of the Kingdom of Eswatini signed a five-year Memorandum of Understanding (MOU) on global health cooperation that includes strategic investments to strengthen national health efforts, leverage American technology, and facilitate the long-term sustainability of Eswatini’s health system. The Department of State, working with Congress, intends to provide up […]
The 4 most innovative tech products we tested this year (includes a surprise tri-fold phone)
From AI glasses with digital overlays to robot vacuums that can pick up your leftover laundry, here are ZDNET's Breakthrough Award winners for 2025.
Innovation Requires Striking The Right Balance
Innovation takes time. It requires a sustained commitment to trying — and often failing — to forge breakthroughs.
Business school grad 'rebuilt' himself throughout ASU journey
W. P. Carey School of Business graduate David De Sousa wants future students to know that his ASU journey is proof that your past does not define your future.
SFA students blend pop culture, business innovation at Swift-Mas Showcase
NACOGDOCHES, Texas –– Students in Stephen F. Austin State University’s Nelson Rusche College of Business stepped into the spotlight during finals week for the Swift-Mas Showcase, an event supported by SFA’s Arnold Center for Entrepreneurship that highlighted student innovation and creative problem-solving throughout the fall semester.
Ghost particles slip through Earth and spark a hidden atomic reaction
Scientists have managed to observe solar neutrinos carrying out a rare atomic transformation deep underground, converting carbon-13 into nitrogen-13 inside the SNO+ detector. By tracking two faint flashes of light separated by several minutes, researchers confirmed one of the lowest-energy neutrino interactions ever detected.
Dueling health care plans fail in the Senate as ACA premium deadline approaches
Competing health care plans failed to meet the 60-vote threshold in the Senate Thursday. With federal ACA subsidies set to expire, health insurance costs are expected to surge in the new year.
Framework Raises DDR5 Memory Prices By 50% For DIY Laptops
Framework Computer had worked to keep their memory prices lower than other laptop vendors amid the ongoing memory shortages throughput the industry worldwide
WTHR to serve as the official broadcast partner for the 2026 Indy Ignite season
Senator Demands Federal Agencies Halt Small Business Contracts, Citing Investigation of Native Hawaiian Firm
Joni Ernst, chair of the Senate Small Business Committee, sent letters to 22 federal agencies saying the no-bid contracts granted through a Small Business Administration program are a “fraud magnet.”
First look at One UI 8.5 on Galaxy S23 Ultra: What’s new and what’s missing
Samsung has started working on One UI 8.5 for Galaxy S23 Ultra, which was confirmed through the software server’s listing. The update will bring plenty of new features to the device, and the first hands-on video has just arrived. Folks over at SamMobile gained access to internal One UI 8.5 and installed the firmware on […]
Science-minded artisans help WHOI move forward at Woods Hole shop
Three Woods Hole Oceanographic Institution employees make ocean-inspired art to support organization's mission. Here's where to find it.
The greatest Tyne-Wear derby moments?
When you have a rivalry as fierce and as storied as the Tyne-Wear derby, you are never short of memorable moments. With Sunderland and Newcastle set to face each other for the first time in the Premier League since 2016 on Sunday, we have taken a trip down Memory Lane to find some of the standout moments. Neither team came into the match in great form, but there was particular pressure on Newcastle boss Ruud Gullit after three defeats in the opening four games.
Thailand dissolves parliament, heightening political turmoil as Trump seeks to salvage ceasefire with Cambodia
The escalation broke the ceasefire brokered in July by Trump who threatened to halt trade talks with the two countries unless they ended the fight.
The nation’s cartoonists on the week in politics
Every week political cartoonists throughout the country and across the political spectrum apply their ink-stained skills to capture the foibles, memes, hypocrisies and other head-slapping events in the world of politics. The fruits of these labors are hundreds of cartoons that entertain and enrage readers of all political stripes. Here's an offering of the best of this week's crop, picked fresh off the Toonosphere. Edited by Matt Wuerker.
These Bucs uniforms are so 🔥
The Tampa Bay Bucs are going old school with the throwbacks.
Lions-Rams Preview
INGLEWOOD, Calif. (AP) Nearly five years after the Los Angeles Rams blindsided Jared Goff by trading him to Detroit for Matthew Stafford, practically all parties involved in the blockbuster deal are thriving on the field and seemingly content about their fate.
Connecting through food: UC Davis Health chefs visit with local students
Chefs Jet Aguirre and Santana Diaz inspired local high school students by sharing their passion for cooking and the importance of healthy, locally grown food.
First-year Huskers boost MotoAmerica through inaugural Business Battle
"Most business schools wait until junior and senior year before introducing students to industry professionals, but we wanted to do that for our freshmen. Day one, we introduced them to corporate partners, real-world business challenges and mentors from our business community." —Laurie Miller, associate dean of undergraduate programs and curriculum, College of Business
Trump seeks to cut restrictions on marijuana through planned order
The president is expected to attempt to classify marijuana similar to some common prescription painkillers and other drugs.
Taking Stock of Elevance Health (ELV)’s Valuation After Digital Health Push and Board Refresh
Elevance Health (ELV) just paired a broader rollout of its AI powered Virtual Assistant with the appointment of veteran healthcare deal maker and governance expert Amy Schulman to its board, a combination investors should parse carefully. See our latest analysis for Elevance Health. Those digital health moves and the Schulman appointment are landing against a clear shift in sentiment, with the share price up 14.3 percent over the past month but a three year total shareholder return still...
Revived Patriots face Bills test in hunt for playoffs
High-flying New England face a mouth-watering test against Josh Allen's Buffalo Bills Sunday, seeking a win over their AFC East rivals that would secure the Patriots a playoff berth and the divisional title.They face a mountain to climb against their divisional rivals, the Los Angeles Chargers, who sit three wins ahead in the AFC West.
Texas Business Reforms Show Shareholder Democracy Is Thriving
View our Texas Business Reforms Show Shareholder Democracy Is Thriving insight.
In a setback for Trump, Indiana lawmakers defeat redistricting plan
Republicans resisted the call by President Trump for redistricting. He and the state's Republican governor threatened to back primary challenges against Senators who wouldn't get on board.
Amendment 29: F.6 Science Activation Final Text and Due Date.
The Science Mission Directorate Science Activation Program encourages all people to actively participate in science through activities and resources developed
Justice Department again fails to reindict N.Y. AG James, AP source says
A judge threw out the original indictment against James and Comey in November.
Turkey’s Largest City Is Threatened by a Lurking Earthquake
Escalating activity along a fault line in the Sea of Marmara is moving closer to Istanbul, seismologists warn.
WATCH: Rep. Thompson calls on Noem to resign for 'making America less safe'
Disney CEO Bob Iger Says OpenAI Deal Gives Entertainment Giant 'A Way In' to AI
The Walt Disney Company and OpenAI announced a deal Thursday that will make Disney characters available through the ChatGPT maker's image and video generation tools, and see Disney invest $1 billion in OpenAI.
Lorwyn Eclipsed's Proliferating Elf Commander Might Put Lathril Out of Business
Christmas comes early for elf players with a brand new Golgari elf commander that brings back proliferation, -1/-1 counters, and introduces us to the new blight mechanic from Lorwyn Eclipsed!
Mayor Adams weighs in on his legacy, achievements
He will leave as New York City’s second Black mayor, and the first one-term mayor in more than three decades.
Asked about The Donald’s national security strategy, the Commons was remarkable for its absences
You’d think MPs would be lining up to decry the US president’s threat to destabilise Europe. Instead, only backbenchers and a few junior ministers bothered to turn up
FMOL Health has purchased this property near Our Lady of the Lake
FMOL Health has acquired a kidney care facility property on Flanders Drive near Essen Lane. The system purchased the site through Our Lady of the Lake Hospital Inc. from Flanders Building LLC f… Already an INSIDER? Sign in. We are glad you enjoy reading Business Report. Continue reading this story and get ACCESS to all […]
Penske Entertainment establishes formal Independent Officiating Board for IndyCar
Comprised of three members tasked with presiding over the IndyCar Series and its Indy NXT development series, the IOB reports to a new non-profit entity, IndyCar Officiating, Inc, created by Penske Entertainment.
Dueling Senate bills to address health care affordability fail to pass
The Senate today failed to pass legislation to address health care affordability. The chamber first voted on a Republican-backed bill that failed by a 51-48 vote. The bill would have disbursed $1,000 in health spending accounts for individuals age 18-49 and $1,500 for those age 50-64. A Democrat-led plan that would have extended the enhanced premium tax credits for three years also failed by a 51-48 tally. The bills needed 60 votes to pass.
Breakthrough 3D wiring architecture enables 10,000-qubit quantum processors
The novel 3D wiring architecture and chip fabrication method enable quantum processing units containing 10,000 qubits to fit in a smaller space than today's 100-qubit chips.
Disney bets $1 billion on OpenAI in deal that opens its vault of characters to ChatGPT and Sora
Darth Vader and other Disney characters are coming to ChatGPT and OpenAI's Sora AI video app as part of a three-year licensing deal.
Live updates: Dueling Senate health care plans come up for votes; US, Venezuela tensions rise
Senators will go on record Thursday on competing health care plans that try to address enhanced ObamaCare tax subsidies set to expire at the end of the year. A vote on the Democrats’ three-ye…
Meet the winners of our Athlete of the Playoffs polls for the fall sports
Be sure to check providencejournal.com/sports each week for the Longplex Athlete of the Week polls throughout the winter sports season.
Ed and Linda Whitacre contribute $7M to support health research, engineering and athletics at UT San Antonio - UT San Antonio Today
The Whitacres’ continuous investment in UT San Antonio demonstrates how philanthropy can advance education, discovery and health.
Moderna Founder Warns US Doubts on Science Threaten Biotech Edge
The US risks falling behind in biotechnology as the government cuts funding and skepticism over vaccines grows, according to Moderna Inc.’s co-founder and Chairman Noubar Afeyan.
Poppin' Tags Free Store owner extends mission with funds, new business
Sonya Dembowski remembers the moment she decided to begin her Poppin’ Tags Free Store in West Deer. She was driving through Coraopolis in the height of the pandemic shutdown. She remembers seeing piles of donations left outside a closed store. Dembowski later saw on the news that because the donations
Mental health needs of people with intellectual and developmental disabilities can't be ignored
William Skipworth’s three-part investigation in the New Hampshire Bulletin has laid bare the ongoing traumas experienced by people with intellectual and developmental disabilities. The community’s response has been swift — shock, grief, and a collective demand for action to prevent future harm. As the dust settles, pressing questions are emerging about oversight and accountability: Which […]
907 Sports: An in-depth look at the Alaska Sports Hall of Fame Class of 2026
The Alaska Sports Hall of Fame announced it’s Class of 2026 earlier this week, inducting three people and two moments.
Turning Passion Into Purpose Through Science and Resilience
A first-generation college student and parent, Tearica Moore is graduating Saturday with a bachelor's degree in biology.
Scientists say thousands of tiny black holes may be passing through your home every day | - The Times of India
Trending News: Physicists reveal that thousands of primordial black holes may drift through your home every year, undetected. Learn how these tiny, ancient black holes could be linked to dark matter and what that means for us.
It’s not just Americans who are feeling US tariffs. Five charts show their global impact
There are signs steeper US tariffs, introduced by US President Donald Trump, are feeding through to higher prices for Americans. But they are also inflicting pain beyond US borders. We look at examples from around the world.
Social media and ADHD diagnosis, new mpox strain in England and early firestarters
Science editor Ian Sample sits down with co-host Madeleine Finlay to discuss three eye-catching stories from the week
The New WHO Pandemic Treaty and Global Health Governance: Incorporating Common but Differentiated Responsibilities into PABS - Georgetown Journal of International Affairs
On May 20, 2025, the World Health Assembly unanimously adopted the World Health Organization (WHO) Pandemic Agreement, an international treaty designed to strengthen pandemic prevention, preparedness, and response. The product of three years of arduous negotiations, the treaty marks a new era of global cooperation in public health. However, core aspects of the agreement remain unresolved—notably the Pathogen Access and Benefit-Sharing (PABS) System, which is intended to ensure equitable access to pandemic-related materials and benefits. To support the successful implementation of the WHO Pandemic Agreement, the principle of “common but differentiated responsibilities” should be formally incorporated into the negotiating agenda of the PABS annex. Introduction For the first time, an international treaty has enshrined the principle of “One Health,” the compelling idea that the health of animals, humans, and the environment all contribute to pandemic risks. SARS (2003), H1N1 (2009–10), Ebola (2014–16), and COVID-19 all emerged through zoonotic spillover from animal hosts—respectively, civets, hogs, and bats. Together, they underscore the need for a coordinated, cross-sectoral approach. The Pandemic Agreement responds to this call, requiring state parties to acknowledge the ecological interplay and commit to a comprehensive “One Health” strategy. Specifically, Article 5 charges governments to address “the drivers of pandemics and the emergence and re-emergence of infectious disease at the human-animal-environment interface,” including wild animal markets, deforestation, and antibiotic overuse. Yet the effectiveness of this “One Health” vision depends equally on the free flow of scientific information and data among countries and institutions. Just as environmental and animal health factors have been neglected in past global frameworks, so too has data sharing been marginalized, despite its centrality to timely detection and response. The Pandemic Agreement takes an important step by requiring governments to enhance data collection and cooperate with the World Health Organization (WHO). However, these provisions will remain aspirational without a robust Pathogen Access and Benefit-Sharing (PABS) annex. The PABS system will determine whether countries and researchers can rapidly exchange pathogen samples and genetic data while ensuring equitable access to resulting research and development, including diagnostics, therapeutics, and vaccines. Without such mechanisms, the treaty’s promise to operationalize “One Health” and strengthen global preparedness will risk becoming largely symbolic, echoing earlier failures to translate shared principles into coordinated action. Equity Concerns When the 2025 Health Assembly adopted the Pandemic Agreement, it left the difficult question of access to pathogens and the sharing of resulting benefits to be addressed in a separate agreement. Negotiations on this separate agreement, PABS, are now underway in Geneva. Yet governments remain divided over fundamental questions of equity between the countries that primarily contribute to the system and those that primarily draw from it—and consequently benefit. For example, wildlife in countries bordering the equator is likely to produce PABS materials, but companies in Europe are likely to use them to develop lucrative products. The most likely contributor countries are likely to be those biodiverse countries around the equator, such as Brazil, the Democratic Republic of the Congo, and Indonesia, where the number of human-mammalian viral host interactions is large. Conversely, countries most likely to benefit from this material are those with the technology, investors, and infrastructure to capitalize on genomic data, such as the United States, EU member states, and Japan. This imbalance reflects a broader pattern seen in prior international frameworks. Now, as in the past, the wealthiest countries in the world (a useful heuristic is membership of the Organisation for Economic Co-operation and Development (OECD)) disproportionately benefit from systems in which pathogens and genomic sequencing data are contributed to a common source. Under the International Agreement on Plant Genetic Resources for Food and Agriculture (the “Plant Treaty” or “Seed Treaty”) and the Pandemic Influenza Preparedness (PIP) Framework, companies from Europe and North America disproportionately withdraw biological samples and data for development into lucrative medical products. Their governments and companies have both statutory and contractual claims to the products that those companies correspondingly produce. PABS appears poised to follow the same pattern. The text calls for strong language on access to pathogens and associated data, but the corresponding benefits that should flow to poorer countries are couched in equivocal or non-binding language. Common but Differentiated Responsibilities To address these inequities, the principle of “common but differentiated responsibilities” should be formally incorporated into the negotiating agenda of the PABS annex. Common but differentiated responsibilities are often a feature of climate change negotiations. The basic principle is that, even though all countries should reduce carbon emissions, governments that became rich and powerful through massive carbon emissions (e.g., France, the United Kingdom, the United States) should have a greater obligation to address the resulting crises. Applied to PABS, it would require that governments hosting and supporting companies developing lucrative products carry greater obligations toward the cost of running the PABS system; share benefits or final medical products; and transfer technology to help countries worldwide develop their own capacities to innovate and manufacture vaccines during an emergency. For example, an annex could mandate that any company based in an OECD country that withdraws PABS material would be obligated to donate the resulting diagnostics, therapeutics, or vaccines to the WHO during a public health emergency or pandemic. Questions remain about how robust those donations would be, but the principle is that they should deliver highly significant lifesaving benefits to be equitably shared. Theoretically, this approach mirrors the PIP Framework, in which companies withdrawing influenza samples are required to pay half of the operating costs. In practice, however, the framework has fallen short. The PIP Framework Secretariat has struggled to secure payments from companies, with companies often disagreeing over how much is owed. Additionally, without another pandemic influenza to test the strength of the agreement during a public health emergency, corporate compliance with sharing mechanisms remains unknown. Even if these limitations did not characterize the PIP Framework, partially paying for operating expenses does not address the inequity in access to genetic data and pathogen samples that left less developed countries last in line for COVID-19 vaccines (and, before them, H1N1). Common but differentiated responsibilities would go further, addressing governments’ legitimate grievances regarding information sharing. It would make withdrawals of PABS material and resulting products more transparent, building trust across the board. Enforcement and Enduring Success A key implication of this approach is that the governing mechanism of the PABS must have real enforcement authority. The WHO Pandemic Agreement delegates its core governance responsibilities to a Conference of the Parties (COP)—a governing body composed of one representative from each participating government, similar to those established under the UN Framework Convention on Climate Change and the WHO Framework Convention on Tobacco Control. The proposed WHO Pandemic Agreement COP is charged with oversight functions but ultimately possesses no real authority to compel a government to take any action it does not wish to take. The text does not give the COP the ability to, for example, sanction a party that does not comply with either textual obligations or PABS provisions. In other words, there are no effective mechanisms in place to ensure compliance. Perhaps just as significant, establishing a meaningful enforcement mechanism within the PABS system would strengthen the WHO’s credibility and its ability to ensure compliance across global health governance. By setting a precedent for accountability, such a mechanism could enhance the organization’s authority not only within the Pandemic Agreement but also in enforcing the revised International Health Regulations and other frameworks for public health emergencies. Conclusion The PABS annex can—and should—be different. It should establish clear responsibilities for funding as well as for sharing the diagnostics, therapeutics, and vaccines that result from contributions to the system. The system, in turn, must include a dedicated body empowered to hold governments and the corporations they sponsor accountable for their responsibilities before, during, and after pandemics. Doing so would restore trust in the broader agreement, which was eroded as commitments were repeatedly diluted while parties scrambled to meet their own self-imposed deadlines during the Pandemic Agreement negotiations. A robust PABS Annex would cement a grand social bargain. Wealthier countries and their corporations would gain unimpeded access to scientific information essential for developing and manufacturing lifesaving medical products. As such, they would stand to gain considerable economic benefit. Yet that privilege must be matched with responsibility. The grand bargain must include not only the right to innovate, but also the duty to ensure that innovation serves all. As medical products are developed and produced through collective contributions, every person must have equal access. All human beings deserve an equitable chance to survive—to save their own life, the lives of their families, and the well-being of their communities. … Sam Halabi, JD, MPhil, is the Bette Jacobs Endowed Professor at Georgetown University’s School of Health and the Director of the Center for Transformational Health Law at Georgetown Law. He serves as the co-lead for the WHO’s Working Group on Regulatory Consideration on AI and Health’s training workstream. He earned his JD from Harvard, his MPhil from Oxford, and undergraduate degrees from Kansas State University. Lawrence Gostin, LLD (Hon.), JD, BA, is University Distinguished Professor and Founding Director and Timothy and Linda O’Neill Professor of the O’Neill Institute for National and Global Health Law. He is the author of Global Health Security: A Blueprint for the Future (Harvard University Press, 2021); Global Health Law (Harvard University Press, 2014); Public Health Law: Power, Duty, Restraint (University of California Press, 3rd ed., 2016); Public Health Law and Ethics: A Reader (University of California Press, 3rd ed., 2018); Law and the Health System (Foundation Press, 2014); Principles of Mental Health Law & Practice (Oxford University Press, 2010). He also directs the WHO Collaborating Center at Georgetown University. Image Credit: United States Mission Geneva, CC BY 2.0, via Wikimedia Commons
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