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Business Insider expands Discourse team and hires Arielle Pardes
Our Discourse team, led by executive editor Zak Jason and focused on agenda-setting topical features, is expanding.
Darling completes sale of sausage casings business to SARIA
Sale positions company for continued growth and value creation potential while optimizing portfolio and reducing debt.
Banijay America Confirms Ben Samek as CEO, Post-Merger With All3Media
Banijay America has confirmed its new structure post-merger with All3Media, as Ben Samek will serve as CEO of the combined company.
Mental health stigma in Japan may deter care
A UC Riverside–led study of mental health stigma in Japan has found a striking gap between the need for treatment and people's willingness to seek it, with high levels of social distancing toward people ...
Entertainment Partners Names UK Boss For European Expansion
EXCLUSIVE: Production management and entertainment payroll firm Entertainment Partners (EP) has a new boss in Britain. Chris Gratton has today been named Executive Vice President and Managing Director...
Entertainment Partners Names UK Boss For European Expansion
Chris Gratton has been named Executive Vice President and Managing Director of Entertainment Partners' UK business.
Sporting KC Weekly Schedule: Oct. 7-10, 2026
Sporting Kansas City returns home to host the Portland Timbers at 7:30 p.m. CT on Saturday at Sporting Park as the club celebrates National Hispanic Heritage Month. Tickets are available on SeatGeek, including a special Latino Heritage Night ticket pack featuring an exclusive luchador mask/hat and a Corona or Coca-Cola
Mary McNamara: As David Ellison names his new empire Skydance, the message is clear: He owns Hollywood
LOS ANGELES — What a surprise. David Ellison has decided to name the Frankenstudio media company created by the merger of Paramount Skydance and Warner Bros. Discovery simply Skydance. And
Spanish PM Pedro Sánchez looks for political lifeline in snap election
Embattled Socialist leader aims to capitalise on housing crisis to remain in power
Small Businesses Skip the Cross-Border Plumbing Big Companies Can’t Escape
Conventional wisdom says large corporations should dominate cross-border payments. They have global banks, treasury teams, negotiated FX rates,
Silly Dillys Wins $30,000 at RISE Up Harlingen Business Pitch Competition
Silly Dillys captured first place and a $30,000 award at the third annual RISE Up Harlingen Business Pitch Competition, leading a group of local entrepreneurs receiving financial support to develop and expand their businesses.
Traders Purchase Large Volume of Call Options on Sphere Entertainment (NYSE:SPHR)
Sphere Entertainment Co. (NYSE:SPHR - Get Free Report) saw unusually large options trading activity on Monday. Traders bought 9,775 call options on the company. This represents an increase of 1,615% compared to the typical volume of 570 call options.
CT Business Blend: Oct. 5, 2026
Hartford Business Journal’s Greg Bordonaro and WTIC’s Brian Shactman explore the people, companies and trends shaping Connecticut’s business scene every Monday at 8:30 a.m. on WTIC 1080 AM.
GloRilla expands her business brand with 'glam on demand' GloVerse
Memphis rapper GloRilla is expanding her business portfolio with GloVerse, which aims to help connect consumers with verified beauty professionals.
How will humans of the future be augmented? Six striking ideas from science fiction
From expanded vision to immortal bodies, these screen depictions have all stretched our understanding of what technology could do to humans.
Businesses Finding It Harder to Predict AI Spending
Companies are reportedly finding it increasingly difficult to forecast their AI spending. That’s according to a report Monday (Oct. 5) by The Wall Street
Can Democrats expand their Senate map?
Plus: Will Ken Paxton's estranged wife help him win?
The Legend of Zelda: Master Collection Officially Announced
A partnership between Nintendo and Panini offers a new opportunity for collectors and fans.
Livelong Women’s Health Summit Builds Momentum for 2027 Expansion
The Livelong Women's Health Summit brought together consumers, clinicians, researchers, and health experts for conversations spanning menopause, strength and performance, brain health, nutrition, hormones, and the science of aging. The Health & Fitness Association (HFA) served as a sponsor for the event.
Nobody remembers your EBITDA at your funeral
David Mammano highlights the importance of balancing profit with purpose in business to build companies that employees, customers, and communities value.
Science Corp. Announces Long-Term (36 Months) Results of PRIMA BCI Clinical Trial Showing Durable Vision Restoration in Blind Patients Suffering from Geographic Atrophy
Science Corporation, the neural engineering and brain-computer interface (BCI) company, today announced long-term (36 months) followup data from its pivotal ...
2026-27 MLS NEXT schedule: Key dates to know
By MLSsoccer staffThe 2026-27 MLS NEXT season will be the seventh and largest in league history, expanding national competition and player development opportunities across North America's top youth so...
Chevron elevates CFO to head oil and gas operations
HOUSTON, Oct 5 (Reuters) - Chevron Chief Financial Officer Eimear Bonner will become president of the US oil producer's oil, products and gas business, the company said on Monday.
Lions’ Jahmyr Gibbs Decision Makes Absolutely No Sense
Jahmyr Gibbs received just 15 carries against the NFL’s worst run defense as the Detroit Lions fell 32-26 to the Carolina Panthers.
Memorial Health team highlights support, expanded services during Breast Cancer Awareness Month
October is Breast Cancer Awareness Month, and Memorial Health System is using the time to highlight breast health education, early detection and the support available locally for patients and families.
Jeffries says House Democrats aiming to repeat 2018 sweep by flipping Trump districts
The Democratic Party is working to expand the map by going on offense in Republican-held districts, while President Donald Trump hits the trail in a red-state sprint to boost voter enthusiasm and shore up support from his base.
Neighborhood Intelligence Provides Business Update and Announces $45.5 Million Equity Financing with Participation from Management and a Single Institutional Investor
NASHVILLE, Tenn., October 05, 2026--Neighborhood Intelligence (NASDAQ: NXH) ("Neighborhood" or the "Company") today announced that it has entered into a definitive agreement for the purchase and sale of an aggregate of 16,485,508 shares of its common stock (or pre-funded warrants in lieu thereof) at a purchase price of $2.76 per share (or pre-funded warrant in lieu thereof) in a registered direct offering. In addition, the Company will issue warrants to purchase up to 16,123,189 shares of common
Sphere Entertainment (NYSE:SPHR) Downgraded by Craig Hallum to "Hold"
Craig Hallum lowered Sphere Entertainment from a "buy" rating to a "hold" rating and set a $132.00 price objective for the company. in a research report on Monday.
Labour standards increasingly shape market access and business competitiveness
A new ILO Brief examines how labour standards and responsible business expectations are increasingly shaping market access, supply chains and business competitiveness in Asia and the Pacific. It highlights the role of employer and business membership organizations in helping companies navigate evolving requirements and promote better labour outcomes.
Conference to Explore Alternatives to Coercive Mental Health Care
The 18th annual Critical Voices Network Ireland (CVNI) conference will take place at University College Cork November 12 and 13, bringing together speakers and participants to explore critical and alternative responses to human distress.
Chimpanzees steal less pineapple from their friends
The new research sheds more light on the evolutionary origins of friendship.
Star Wars Zero Company Has Received Its First Big Discount at Amazon Before Its October Prime Day Sale Begins, Dropping Below $50
Star Wars Zero Company has dropped to a new low price at Amazon ahead of the retailer's Prime Big Deal Days sale event, with a 20% discount across PS5 and Xbox Series X.
Memorial Health team highlights support, expanded services during Breast Cancer Awareness Month
Memorial Health team highlights support, expanded services during Breast Cancer Awareness Month
oasisVRX Expands to the Princeton Area With New Active Entertainment Virtual Reality Destination
/PRNewswire/ -- oasisVRX is expanding with the opening of its second location at Princeton North Shopping Center, 1225 Route 206 in Princeton, New Jersey....
Datavant, ID.me partner on digital identity verification for medical records
Datavant is partnering with identity verification company ID.me to help patients request their medical records faster and more easily via simple digital credentials. | Datavant has teamed up with ID.me to streamline medical records requests, enabling patients to verify their identities digitally and access records faster.
Samsung One UI 9 Rollout: These Galaxy Phones Are Getting Android 17
Samsung’s One UI 9 rollout is expanding. See which Galaxy phones are getting Android 17, which devices are next, and how to check for the update.
Heartland Catfish Unveils New Website
Heartland Catfish Company recently launched a new website in celebration of its 30th anniversary. The site has been refreshed to focus on retail and food service partnerships, give a detailed look at the company’s products and processes and emphasize consumer education about the benefits of U.S. Farm-Raised Catfish as a versatile and healthy protein source. […]
Three Japanese regional banks consider business integration
The Japanese lenders concerned are Procrea Holdings, Akita Bank, and Bank of Iwate.
Hunt Marketing Firm in Oxford Receives Accolade
For the third consecutive year, Hunt Marketing in Oxford has earned a place on the Inc. 5000 list of America’s fastest-growing private companies. Hunt ranked No. 4,009 on the 2026 list. “Being named to the Inc. 5000 list for a third time is meaningful because it validates the growth story we’re building,” said CEO and […]
Lexology Index Recognizes Five Hecker Fink Partners in 2026 Business Crime Defence Guide
Hecker Fink Partners Shawn Crowley, Jenna Dabbs, Mike Ferrara, Sean Hecker, and Amy Jeffress have been recognized in the Lexology Index guide for Business Crime Defence. The 2026 guide honors leading lawyers worldwide who “stand out among peers for their exceptional work representing companies, corporate officers, and individuals in criminal litigation arising from their business activities.”
Indonesia and China to strengthen science and education cooperation
Indonesia and China plan to expand cooperation in higher education and science to advance innovation and technology adoption.
The AI Advantage Minnesota Has Been Building for Decades
Software companies used to defend themselves in a handful of reliable ways. They built useful features, made their products easy to use and counted on the hassle of switching platforms to keep their customers from leaving. A new company that wanted to compete had to invest months, sometimes even years, of engineering time to catch
Reclaiming 'Health Sovereignty': EU Gastein Forum Confronts A Fragmenting Global Order
Health, long treated as a sanctuary of diplomatic consensus, has entered an era of high politics and ideological division. Leading the closing panel of the EU Health Forum Gastein (EHFG) on Friday (2 October), session chair Ilona Kickbusch, founder of the Global Health Centre at the Graduate Institute in Geneva, highlighted how recent votes at the UN General Assembly demonstrate that nation-states increasingly split and vote instead of searching for consensus.
‘An anchor’: Oakshire fans celebrate, grieve as business prepares to shut down
Oakshire Public House has been a gathering space in the Whiteaker neighborhood since 2013 and holds many individual and community memories. Oakshire as a company is closing, but it plans to transition the Public House to a new company in the next two months, keeping the location open through the process.
Universal Expands EMEA Retail and Partnerships for 'Shrek 5'
Universal builds excitement for 'Shrek 5's' summer 2027 release with new EMEA retail, events and partnerships. Donkey spin-off film set for 2028 release.
Virtual care firm Populus Health Technologies names Catalano as chief revenue officer
Populus Health Technologies, a virtual care media and technology company, announced the appointment of Joe Catalano as chief revenue officer.
Move over kimchi, natto is appearing in health food shops everywhere
Japan’s smelly, slimy beans are highly nutritious but you’ll need ‘nerves of steel’ to eat them
'Totally Spies!' Expands Licensing with Apparel and Jewelry Deals
Banijay Kids & Family announces new "Totally Spies!" licensing agreements spanning apparel, jewelry and publishing as the franchise marks 25 years.
Business Roundup: Latham Aldi sets opening date, women-only gym expands into Slingerlands
Here's what's new in the Capital Region business scene.
The Optimist: A statement win and a much needed rest
The Panthers head into a much needed bye week with head held high
Jobs in health care. Jobs for women. The US labour market is segmenting. Chernobyl’s radiation and Lenin’s love of literature.
Thank you for opening your Chartbook email. Elmer Bischoff, Two Figures at the Seashore, 1957 The only really dynamic job-creator in the US economy is health care: The largest crunch has come in Federal government, which has shed 2.7 m jobs. Source: tchouvkov on Twitter Tech is struggling. [ Joey Politano 🏳️🌈@JosephPolitano The US tech sector continues bleeding jobs in official data released today—overall, employment decreased by 17k last month and is down 69k over the last year That's nearly as bad as the worst of the 2024 tech-cession, and much worse than the 2022 boom or even pre-2020 norms 12:42 PM · Oct 2, 2026 · 15.2K Views 15 Replies · 47 Reposts · 390 Likes ](https://x.com/JosephPolitano/status/2106001807847940232?s=20) The new jobs are all for women. [ Justin Wolfers@JustinWolfers I'm not sure who saw this coming, but so far nearly all the jobs created during the second Trump administration have gone to women. 1:09 PM · Oct 2, 2026 · 33K Views 70 Replies · 146 Reposts · 644 Likes ](https://x.com/JustinWolfers/status/2106008723533533601?s=20) Meanwhile, real wages are being eaten up by modest over-target inflation. [ Heather Long@byHeatherLong The financial pain is real: Wage growth fell to 3% (y/y) in September. That's the lowest in 5 years. Wage growth: 3% Inflation: ~3.4% Inflation has eaten up all wage gains for the average worker since April. Many people are having to make hard choices about what to buy and what … 1:24 PM · Oct 2, 2026 · 37K Views 24 Replies · 275 Reposts · 533 Likes ](https://x.com/byHeatherLong/status/2106012367712620728?s=20) HEY READERS, THANK YOU for opening the Chartbook email. I hope it brightens your day. I enjoy putting out the newsletter, but tbh, what keeps this flow going is the generosity of those readers who clicked the subscription button. If you are persuaded to click, please consider the annual subscription of $60. It is both better value for you and a much better deal for me, as it involves only one credit card charge. Why feed the payments companies if we don’t have to. Subscribe Elmer Bischoff, Bathers, 1960 Americans are disillusioned with higher ed. For contributing subscribers only. Subscribe Where the Chernobyl radiation went. h/t Simon Kuestenmacher aka simongerman600 How Lenin’s love of literature shaped the Russian Revolution - Tariq Ali This, then, was the intellectual atmosphere in which Lenin came of age. His father, a highly cultured conservative, was the chief inspector of schools in his region and much respected as an educationalist. At home, Shakespeare, Goethe and Pushkin, among others, were read aloud on Sunday afternoons. It was impossible for the Ulyanov family – “Lenin” was a pseudonym adopted to outwit the tsarist secret police – to escape high culture. At high school, Lenin fell in love with Latin. His headteacher had high hopes that he might become a philologist and Latin scholar. History willed otherwise, but Lenin’s passion for Latin, and taste for the classics, never left him. He read Virgil, Ovid, Horace and Juvenal in the original, as well as Roman senatorial orations. He devoured Goethe during his two decades in exile, reading and rereading Faust many times. Lenin put his knowledge of the classics to good use in the time leading up to the October revolution of 1917. In April of that year, he broke with Russian social-democratic orthodoxy and, in a set of radical theses, called for a socialist revolution in Russia. A number of his own close comrades denounced him. In a sharp riposte, Lenin quoted Mephistopheles from Goethe’s masterwork: “Theory, my friend, is grey, but green is the eternal tree of life.” Source: The Guardian Elmer Bischoff, The River, 1953 If you’ve scrolled this far, you know you want to click: Subscribe
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth
Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine
Dan Campbell: I'm not talking about firing Kelvin Sheppard
The Lions defense was unimpressive in the first three weeks of the 2026 season and things didn't get any better in Sunday night's loss to the Panthers.
Mr Bean Brand Expands with New Global Licensing Partnerships
Banijay Kids & Family announces expanded Mr Bean licensing deals including Royal Stacks burgers, apparel, watches, toys, and arcade games worldwide.
Tetairoa McMillan: Everything just clicked on Sunday night
Panthers wide receiver Tetairoa McMillan's first Sunday night game was one to remember.
King Drive Business Improvement District budget expands for 2027
The Historic King Drive Business Improvement District's 2027 operating plan, which includes a budget increase, will head to the common council for approval.
TendedBar installs countertop beverage system at Clearwater entertainment center
TendedBar has installed its countertop beverage dispensing system at Launch Family Fun Center in Clearwater, Florida, according to a company LinkedIn post.
Data centers become a new political battleground in Tennessee
As opposition grows, AI companies are spending heavily on campaigns and lobbying as data centers reshape Tennessee politics.
Data centers become a new political battleground in Tennessee
As opposition grows, AI companies are spending heavily on campaigns and lobbying as data centers reshape Tennessee politics.
Small businesses need to leverage home field advantage with SEO
Small and mid-sized businesses no longer just compete with the company down the street.
'The Outsiders' review: A dynamic staging at the Hollywood Pantages
'The Outsiders,' winner of the 2024 Tony for best musical and based on the classic S.E. Hinton novel, has its L.A. premiere at the Hollywood Pantages Theatre.
Scientists win Nobel Prize in medicine for work on ‘light-gated ion channels and optogenetics’
Scientists to Karl Deisseroth, Peter Hegemann and Georg Nagel won the 2026 Nobel Prize in Physiology or Medicine.
Sunderland Youngster Enjoys Major Career Milestone On International Duty
Sunderland striker Juan Riquelme Angulo scored his first senior Ecuador goal against Panama.
An 8-justice Supreme Court to decide whether cities can sue oil companies for climate change impacts
The Supreme Court will hear arguments Monday in one of the most important climate change cases to reach its docket in years, a multibillion-dollar effort to hold major oil companies like ExxonMobil liable for the damages caused by planet-warming pollution.
To Make More Money, Rolls-Royce Is Aiming Higher on Price, Not Production
The luxury carmaker is expanding its factory in Britain to focus on rarefied custom cars. First up is a $3.5 million-plus electric roadster.
Republicans and Democrats find a unifying target: Pharmacy benefit managers
Republicans and Democrats, both patients and politicians, seem united in their disdain for the healthcare companies known as pharmacy benefit managers. Tennessee and Arkansas are regulating them now.
HEALTH AND FITNESS: Celebrate Walktober by going for a walk
Now that the extreme heat of our seemingly endless summer weather is behind us, being active outdoors is more enjoyable. October is a great time to get outdoors and go for a walk! That is the spirit of Walktober, an initiative adopted by health organizations, companies and communities around the globe.
Pee Dee business leaders worry poor infrastructure, workforce shortages will limit economic growth
Pee Dee business leaders have high ambitions to expand commercially and develop the region, but many also worry that utility and infrastructure issues could limit economic growth.
New Small Business Alliances Signal Competitive Positioning by 18+ IT and Consulting Leaders Across FedCiv, FedHealth, and DoD
In the GovCon IT and consulting market, some companies react to opportunities. Others shape the board well before the game begins. Mentor-protégé agreements fall squarely into the latter category. These partnerships are not administrative check-the-box exercises. They require sustained commitment, alignment at the leadership level, and a clear view of where the market is heading. […]
Southern Taiwan Science Park revenue climbs 36.5% in first eight months of 2026
Companies in the Southern Taiwan Science Park (STSP) posted record revenue of NT$2.495124 trillion (US$78.59 billion) in the first eight months of 2026, up 36.5% from a year earlier, according to the STSP Bureau. The bureau said the growth reflected the global AI boom and the park's expanding role in the high-tech supply chain.
ASUS Announces New 64GB Configuration of the Ascent GX10
ASUS today announced a new 64 GB configuration of ASUS Ascent GX10, expanding the lineup alongside the existing 128 GB model. This compact AI supercomputer is designed to bring local agentic AI development within reach of more developers, researchers and data scientists. Based on the NVIDIA DGX...
Turkish-Japanese Science and Technology University opens in Ankara
Turkish-Japanese Science and Technology University, a joint project agreed on by the two countries in 2013, opened Monday in Ankara, offering undergraduate courses in engineering and doctoral programs in artificial intelligence and earthquake science.
Seven-goal Clásico keeps Barcelona five points clear
Barcelona beat Real Madrid 7-0 in Liga F on Sunday, with Clàudia Pina scoring four goals to extend the Blaugrana’s perfect start and open a five-point lead at the top. The Guardian reported that mo...
Euro zone business growth hits over 3-1/2-year high despite inflation worries, PMI shows
BENGALURU, Oct 5 (Reuters) - Euro zone business activity expanded at its fastest pace in nearly 3-1/2 years in September as demand remained strong despite inflation worries stemming from the Middle East war, according to a private survey which also showed resurgent price pressures.
Euro zone business growth hits over 3-1/2-year high despite inflation worries, PMI shows
By Indradip Ghosh BENGALURU, Oct 5 (Reuters) - Euro zone business activity expanded at its fastest pace in nearly 3-1/2 years in September as demand remained strong despite inflation worries stemming from the Middle East war, according to a private su...
Uncovered raw shrimp a tic against wings restaurant
The following is a list of restaurants in Richmond and Columbia counties that were inspected Sept. 25 through Oct. 2, accompanied by their scores and, in some cases, the health infractions that lowered those scores. Scores below 70 are considered failing.
Total Access Elevator Buys Competitor
Total Access Elevator, an elevator servicing company based in Santa Fe Springs, has made its fourth acquisition in a buying spree aimed at gaining market
Spain services growth accelerates despite cost surge, PMI shows
Oct 5 (Reuters) - The expansion in Spain's service sector picked up pace in September as increased demand lifted activity despite a surge in operating expenses, a business survey showed
Closed Business Day highlights importance of online security for businesses
On 5 October, the day after Open Business Day (an open door in hundreds of companies), the Centre for Cybersecurity Belgium (CCB) is calling on organisations and businesses to close their doors. Not to the public, but to cybercriminals. With Closed Business Day, the CCB is drawing extra attention to business cybersecurity.
TempraMed Announces VIVI Cap Smart Connectivity with Apple Health and Google Fit, Providing Better Health Outcomes and Data Tracking
VIVI Cap Smart transforms injectable medication protection into a connected health-data layer, enabling patients, caregivers and digital-health platforms to capture medication-use, temperature and adherence signals.Toronto, Ontario--(Newsfile Corp. - October 5, 2026) - TempraMed Technologies Ltd. (CSE: VIVI) (OTCQB: TMPTF) (FSE: 9DY) ("TempraMed" or the "Company"), a medical technology company transforming the storage, protection and management of temperature-sensitive medications, is pleased to
On This Day, Oct. 5: Scientists genetically sequence flu strain behind 1918 pandemic
On Oct. 5, 2005, scientists announced that for the first time they were able to genetically sequence the strain of avian flu that was behind the 1918 pandemic that killed up to 50 million people world...
Studs and duds from Panthers' Week 4 win over Lions
Who ended up as the studs and duds from the Panthers' Week 4 win over the Lions?
YH Entertainment Warns of Investment Fraud Impersonating AND2BLE's Japan Management
YH Entertainment Warns of Investment Fraud Impersonating AND2BLEs Japan Management
Jameson Williams leads Detroit in receiving on SNF
Jameson Williams had a team-high 102 yards versus the Carolina Panthers in Week 4, more than doubling his previous season high.
Disappointing night for Jahmyr Gibbs
Facing the NFL's last-ranked run defense, Jahmyr Gibbs managed just 46 yards on 15 carries in a Week 4 loss to the Panthers.
True Food Kitchen Initiates Voluntary Chapter 11 Proceedings to Position Business for Long-Term Success
True Food Kitchen (the "Company") today announced that it and certain affiliates have filed voluntary petitions for relief under Chapter 11 of the U.S. Bankruptcy Code in the U.S. Bankruptcy Court for the Southern District of Texas (the "Court").
True Food Kitchen Initiates Voluntary Chapter 11 Proceedings to Position Business for Long-Term Success
/PRNewswire/ -- True Food Kitchen (the "Company") today announced that it and certain affiliates have filed voluntary petitions for relief under Chapter 11 of...
Japan’s Nippon To Buy Akzo’s Southeast Asia Decorative Paints Business For $1.35 Billion
The deal gives Nippon Paint—controlled by the family of late Singaporean billionaire Goh Cheng Liang—access to Akzo’s operations across Indonesia, Malaysia, Singapore, Thailand, Vietnam, Papua New Guinea and Australia.
5 winners, 5 losers from Lions’ loss to the Panthers
The Detroit Lions fell flat against the Carolina Panthers and are now facing some serious questions about their team.
Kelley Liu’s Song of Skin to Open SoHo Flagship, Expand CelDot
Kelley Liu is opening Song of Skin’s first permanent store in SoHo, hosting an L.A. pop-up and expanding her K-beauty brand CelDot.
MedX Health Appoints Monaderm as a Representative for SkinSecure™ Across Europe for Beauty and Aesthetics Research
MISSISSAUGA, Ontario, October 05, 2026--MedX Health Corp. (TSXV: MDX), a data-driven skin health analytics company, today announced the appointment of Monaderm, the Monaco-based skin measurement specialist, as a key European sales agent for SkinSecure™, expanding the commercial reach of its non-invasive, objective biological skin measurement technology, which maps collagen, melanin and hemoglobin non-invasively in living skin in a single 30-second capture, across the European cosmetics and skin
Sacramento sisters honor family legacy with dried fruit business
Three sisters in Sacramento have launched Stained Glass Fruit, a company that turns California-grown citrus into dried slices, blending their family’s agricultural history with entrepreneurship.
Sunday Night Football: Tetairoa McMillan's big night powers Panthers to 32-26 victory
McMillan caught 14 passes for 192 yards with two touchdowns against Detroit, as Carolina moved to 2-2 in 2026.
Honor Magic 9 series global launch scheduled for January 2027
Honor Magic 9 series is set to hit the global launch stage in January 2027. As per the company’s official announcement, the flagship smartphone is coming to overseas markets, starting in Europe early next year after a successful Chinese launch. Magic 9 series made its debut in China last week, and Honor has begun preparing […]
Chuba Hubbard's second TD gives Panthers 29-19 lead
The Panthers punted on their first drive.
Inside the court case for the brother of Hayden Panettiere's boyfriend
Zach Hickerson, brother of late actress Hayden Panettiere's boyfriend Brian Hickerson, is looking to resolve a case that landed him behind bars earlier this month.
They survived World War II and lost decades, but not 2026. Japan's century-old businesses are disappearing at a record pace
Japan’s century-old businesses face mounting pressures from rising costs, labor shortages, a shrinking market and succession challenges.
Amidst Conflict in the Gulf, Oman's Duqm Drydock Sees Business Boom
The Asyad Group’s Drydock subsidiary, which operates a substantial facility within the inner harbor at Duqm in Oman, has seen a massive expansion of i...
Georgia Tech And Amazon Launch Science Hub For AI, Robotics, And Logistics Research
Georgia Tech and Amazon have launched the Georgia Tech-Amazon Science Hub, expanding a decade-long research relationship between the university and technology company. Amazon will provide funding for joint research projects and community-building initiatives through the new hub.
