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Bears’ Caleb Williams: ‘Iceman’ trademark application is to protect my business interests
He applied for a trademark last month.
Sphere Entertainment (SPHR) Is Up 17.4% After Wizard of Oz-Driven Revenue Surge and Global Expansion Plans
Sphere Entertainment recently reported past-quarter revenue growth of 28%, powered by the success of its “Wizard of Oz at Sphere” production in Las Vegas, which has sold more than two million tickets and helped narrow operating losses in the Sphere segment. On the back of this stronger performance, the company is now moving ahead with international Sphere developments in Abu Dhabi and National Harbor, signaling a push to replicate its immersive venue model beyond the US. We’ll now examine...
Las Vegas entertainment icon stages backyard production
Mac King and several comedy-magic friends put on a whopper of a show at his house.
United Airlines adds new fees to cheapest business-class fares
How would you feel if you paid $2,000 or more for a business-class ticket but still had to pay a fee if you wanted an advance seat assignment?
A look inside the digital backbone of business
AI and data systems are transforming the modern Midwestern workplace
‘We watched them die before our eyes’: Sudan health workers helpless amid medical shortages
As violence forces tens of thousands to flee Sudan’s South Kordofan state, doctors in a key maternity hospital are facing impossible choices – with too few supplies, too many patients, and lives slipping away.
Palumbo family business secrets revealed in settlement agreement with IDOT
It turns out there were more connections than previously known between Sebastian "Sam" Palumbo, his construction firms and a road-building group overseen by relatives known as Builders Companies. But the firms insist those ties didn't violate Palumbo's agreement not to participate in state or federal contracts following a 1999 guilty plea in a racketeering case.
Is Brain Health the Next Healthcare Frontier?
Arianna Huffington breaks down the impact of daily behaviors on brain health.
Xiaomi reveals how much smartphone costs have actually risen due to the DRAM crisis
For the first time, Xiaomi has commented specifically on the impact of the DRAM crisis, revealing the extent to which the rising costs of RAM and flash memory are affecting the production costs of a smartphone.
Kids Need Rec Sports To Make a Comeback
America’s system of youth sports fails kids and families, writes Gail Cornwall.
Sphere Entertainment (SPHR) Stock Is Up, What You Need To Know
Shares of content production and distribution company Sphere Entertainment (NYSE:SPHR) jumped 4.2% in the afternoon session after Guggenheim raised its price target on the stock to $160 from $150 while keeping a Buy rating.
Kat Abughazaleh expands political network, keeps campaign office open as mutual aid hub after primary loss
On Thursday, Abughazaleh announced in a video that she will help campaigns "integrate mutual aid and direct action into their races," and she plans to help races across the country, "especially in the Midwest."
Trump signs 100% tariff on brand-name pharmaceuticals
Drug companies that commit to moving production to the U.S. will face a 20% tariff and no tariff if they also agree to lower prices.
Sphere Entertainment (SPHR) Stock Is Up, What You Need To Know
What Happened? Shares of content production and distribution company Sphere Entertainment (NYSE:SPHR) jumped 4.2% in the afternoon session after Guggenheim r...
Broadway's 'Six' leads New Orleans theater shows this week, from 'Little Women' to 'Irish Curse'
Dive into history with "Six," embrace sisterhood in "Little Women," and laugh with "The Irish Curse." Tickets available now for these captivating productions!
Kirk Cousins agrees to sign with Raiders
While Las Vegas is expected to select Fernando Mendoza at No. 1 overall, Cousins gives the club a veteran option at QB.
17 wide receiver draft prospects who fit Packers production benchmarks
There are production trends among Green Bay's previous draft picks at receiver, and there is a healthy list of prospects who fit the bill in 2026.
Presidio landman Brett Barnes: 'This business is in my blood'
Brett Barnes is general counsel for Presidio Production, a Fort Worth upstream oil & gas company. But Barnes is a landman.
Who Is Lee Zeldin? Possibly Trump’s Next Attorney General
The current EPA administrator has been floated as a possible replacement for Pam Bondi who reportedly may soon be dismissed.
Hollywood Disaster: Jobs Crater By 30% As LA's Entertainment Industry Destroys Itself With Politics
A staggering 30% drop in film and TV employment since 2022 has experts warning that Los Angeles is following the path of Detroit as production flees the high-cost city.
What to Eat for Better Heart Health, According to New Guidelines
The American Heart Association updates its advice for what to eat to maintain a healthy heart.
'Ferris Bueller's Day Off' book reveals the '80s star who almost beat out Matthew Broderick for title role
Another notable John Hughes collaborator could have portrayed Ferris Bueller, according to an upcoming book about the production of 'Ferris Bueller's Day Off.'
After their best season in 20-plus years, Century's Science Olympiad team is building for the future
This season, the school’s Science Olympiad team ranked second at the state tournament.
Cardinal Health expands Actinium-225 production capacity to support growing demand for novel cancer therapies
/PRNewswire/ -- Cardinal Health (NYSE:CAH) today announced a significant expansion of its Actinium-225 (Ac-225) production capabilities at the company's Center...
Young scientists compete in the 2026 Chester County Science Research Competition
Young scientists from across Chester County once again met for the chance to showcase their knowledge and engage in friendly rivalry at the 2026 Chester County Science Research Competition.
Roger Goodell: The Rooney Rule isn't going anywhere
"The one thing that doesn't change is our values," Goodell said.
Andy Reid: Justin Fields is "more than a gadget guy"
With Patrick Mahomes on the mend from a torn ACL suffered late in the 2025 season, there's certainly a chance he won't be ready for the start of the regular season.
NFL passes rule regarding kickoffs from the 50
The NFL has approved a rules change that will eliminate the kicking team’s incentive to intentionally kick the ball out of bounds when kicking off from the 50-yard line.
Sports and art come together for 2026 SWISH Arts & Culture Festival
The citywide fest will take place April 3-6 alongside the NCAA Men’s Final Four.
America Needs Reproductive Health Leave
Too often, "women have to choose between working through unbearable pain, losing income they can’t afford to go without, or tapping into a limited number of sick days," writes Congresswoman Ansari.
Hasbro Entertainment Names Rob Doherty VP of Production
Doherty will run production across Hasbro’s animation and digital content slate.
Predicting Harmful Algal Blooms and Toxicity in the San Francisco Estuary
In fall 2023, National Oceanic and Atmospheric Administration (NOAA) awarded a five‑year, $3 million Monitoring and Event Response Research Program (MERHAB) grant to improve Harmful Algal Bloom (HAB) detection in the San Francisco Estuary.
How Can We Improve Representation in Major Scientific Conversations?
Women, early-career researchers, and global scholars are still underrepresented in major scientific conversations. Explore how this manifests and hear from experts on what can be done to improve inclusion.
Texas A&M ranked Top 5 in SEC returning production
Texas A&M will reportedly return a solid 65% of its 2025 roster heading into the 2026 season, which ranks 5th in the SEC.
Eidos-Montréal announces 124 job cuts; studio head David Anfossi departs after 19 years at developer
Decision made following "changing project needs and impacts across production and support teams"
2026 NFL Draft Scouting Report: Michael Taaffe, S, Texas
Texas safety Michael Taaffe offers instincts and production at a deep position group in the 2026 NFL Draft.
SBA offering low-interest loans to residents, businesses impacted by last year's severe storms
Residents and businesses in six counties, including Cook, can apply for federal disaster loans if their properties were damaged by storms in August 2025.
Quilty Launches as the Entertainment's Intelligence Platform
Today, Quilty launches as the first unified intelligence platform for the entertainment industry, a new tool set that consolidates creative analysis, writer development, packaging, market forecasting, production planning, industry introductions and legal intelligence. Founded by Simon Horsman, a technology and entertainment lawyer and film, television, and theatre producer, alongside technology entrepreneur and film producer, Daniel Wood, Quilty was created to address the global entertainment in
Hasbro Entertainment Hires Animation Veteran Rob Doherty as New VP of Production
Hasbro Entertainment has announced the appointment of Rob Doherty as Vice President, Production. He will oversee production across Hasbro’s expanding animation and digital content slate, supporting the company’s continued growth in the space. Doherty brings over 30 years of experience in the kids’ television industry, with deep expertise in development and international co-productions. He has […]
Roundup: LNG milestone / Final investment decision / TSA funding
Production begins: A major LNG project on the Texas-Louisiana border has begun production, marking a key milestone for U.S. energy exports as global supplies tighten. The QatarEnergy–ExxonMobil joint venture is preparing to ship its first cargo in the coming months, positioning the facility as a critical new supply source amid geopolitical disruptions impacting global gas […]
Hasbro Entertainment Names Rob Doherty VP of Production
The executive brings more than 30 years of experience to the role.
Neil Diamond tribute sure to be ‘So Good!’
BAR HARBOR — Broadway and television star Robert Neary will bring his high-energy production, “So Good! The Neil Diamond Experience,” to the Criterion Theatre in Bar Harbor on Friday, April
National Science Foundation provides $45 million more for ag innovation effort
The NSF AgTech Engine in North Dakota was one of 10 "regional innovation engines" created by $15 million National Science Foundation grants, paid over two years, in January 2024.
Ayaneo discontinues Snapdragon 8 Elite based Pocket FIT console due to rising costs
The Pocket FIT 8Elite was delayed for a few months and it finally started shipping - but this will likely be the last production batch due to high memory costs.
Apple Reportedly Planning to Launch iMac With OLED Display
Apple is preparing to launch an iMac featuring an OLED panel with higher brightness, according to ZDNet Korea. Apple has apparently requested that Samsung Display, LG Display, and other suppliers produce 24-inch OLED panel samples suitable for a future iMac model using their mass-production facilities. This would be the biggest ever OLED display offered on an Apple device.
Nurses are an afterthought in health care debate, and that's deadly
As hospitals consolidate and executive pay rises, nurses and other frontline employees continue to get squeezed. Such pressures stretch patient safety.
Jonah Coleman Analytical Draft Profile
Using his RB Rookie Model, Dan breaks down Jonah Coleman's production, athletic profile, comps and fantasy outlook.
AKC Canine Health Foundation Joins All Access hosted by Andy Garcia to Explore the Science of Veterinary Innovation
The AKC Canine Health Foundation (CHF) is excited to announce a collaboration with the educational program "All Access hosted by Andy Garcia" to develop a documentary segment centered on canine health research. Set to film on April 15, 2026, at the Foundation's headquarters and the North Carolina State University College of Veterinary Medicine, the production will provide an objective look at how independent research improves the well-being of dogs, through highlighting CHF's pivotal role as a f
Injury sidelines Sophie Turner, shutting down 'Tomb Raider' series production
Amazon MGM Studios has hit pause on 'Tomb Raider' while star Sophie Turner recovers from an injury.
Eagles agree to one-year deal with Joe Tryon-Shoyinka
The Eagles are adding a former first-round pick to their defense.
Scientists Stunned: Colossal Eggs Discovered 3,500 Meters Beneath an Active Volcano
Beneath an active seafloor volcano off Vancouver Island, researchers have documented a congregation of giant eggs at roughly 3,500 meters, a discovery that reframes how life can flourish under extreme conditions. The eggs belong to the Pacific white skate, an elusive deep‑sea species adapted to cold, crushing pressure and perpetual darkness. What seemed an unlikely nursery is actually a geothermally warmed refuge, where subtle heat helps embryos survive a marathon incubation. The finding links volcanic energy to a quiet engine of biodiversity, turning a hostile landscape into an incubator. A living volcano, a hidden nursery The seamount long assumed dormant now exhales mineral‑rich, shimmering plumes, proof of hydrothermal life at depth. Expedition cameras swept across black basalt and pale bacterial mats, revealing vents that pulse with warmth. That warmth, though modest by human standards, alters the physics of development for cold‑adapted embryos. In a realm where metabolism creeps, even a few degrees can mean faster growth and higher survival. The volcano is not only active; it is ecologically formative, drafting a blueprint for a thriving oasis. Giant eggs and a skate built for the abyss The Pacific white skate, Bathyraja spinosissima, is built for the abyss: broad wings, armored spines, and a life history that trades speed for endurance. Females lay outsized, rectangular “mermaid’s purses,” often 46–50 centimeters long, packed with rich yolk to fuel years of growth. In the frigid deep, embryos can require around four years to hatch, a timeline that magnifies every energetic advantage. The scale is striking—large eggs, large adults, and a textbook case of deep‑sea gigantism. The volcano’s gentle heat may literally shave months or years from the wait. Why heat matters at the bottom of the sea Hydrothermal circulation delivers low‑level warmth without the turbulence that would scatter fragile egg‑cases. Slightly elevated temperatures accelerate enzyme kinetics, nudging development along while keeping embryos within a safe range. Mineral‑laden fluids likely shape local microbiomes, which, in turn, can influence biofilms on egg surfaces. The environment acts like a slow, steady incubator, countering the deep sea’s tyrannies of cold and scarcity. For a species with long maturation and few offspring, every incremental boost compounds across generations. An ecosystem sculpted by fire and water Seafloor volcanoes create steep environmental gradients, stitching together hot vents, cool eddies, and mineral gardens into mosaic habitats. Microbes harvest chemical energy, seeding food webs that support crustaceans, fishes, and skates. Cameras documented egg‑cases nestled among rocky ledges, near communities nourished by vent‑driven chemistry. These islands of productivity behave like deep‑sea oases, sustaining life far beyond the vent orifice’s flickering light. The nursery’s success underscores how geological forces engineer biological opportunity. “Finding a cradle of life tucked beneath a breathing volcano reminds us that the planet’s harshest places can be profoundly generous.” What the discovery could change The nursery reframes conservation priorities in regions where volcanism quietly underwrites reproduction. Protecting hydrothermal corridors could safeguard entire lifecycles, not just charismatic adults spotted during occasional surveys. It also sharpens questions about how climate‑driven shifts in ocean circulation might influence vent activity, temperature fields, and embryo survival. With methodical mapping, time‑series cameras, and environmental DNA, scientists can track whether nurseries remain stable or drift with geologic rhythms. Key implications include: Enhanced understanding of deep‑sea reproduction at hydrothermal sites. New conservation targets centered on geothermal nurseries. Comparative studies with other volcanic regions, from the Galápagos to rift zones. Biotechnological insights from organisms adapted to long, cold development. Better models of how seafloor heat shapes regional biodiversity. Methods behind the revelation Remotely operated vehicles threaded through chimney fields, gathering video, temperatures, and mineral signatures. High‑definition imagery captured the distinctive, horned egg cases, their edges dusted with fine volcanic silt. Geochemical profiles mapped how heat and chemicals disperse, outlining the “thermal lanes” where eggs most cluster. Combined, these datasets reveal a nursery organized by geothermal topography, with egg‑cases concentrated in pockets of gentle, sustained warmth. A fragile boon in a changing ocean Deep‑sea environments feel remote, yet they intersect with global pressures: mining proposals, cable routes, and shifting oxygen levels. The nursery’s resilience hinges on stable heat flow, intact substrates, and minimal disturbance from noise or sediment. Safeguarding such places is not just about protecting novelty; it preserves a slow, ancient strategy that lets large, long‑lived animals endure in the coldest reaches of the Pacific. Where geology and biology meet, the planet’s deep time still writes living stories. This volcano‑warmed nursery adds a vital chapter to that story, revealing how subtle thermal gifts can tip the scales toward life in the abyss. With each dive, researchers trace the contours of an unseen world, where fire feeds water, and water—against all odds—feeds the future.
Basketball tournament makes space for trans athletes amid international sports bans
The court, split into competitive and recreational sides, pitted players of all genders against each other for 15-minute matchups less than a week after transgender female athletes were banned from women’s events at the Olympics after the International Olympic Committee agreed to a new eligibility policy.
Stablecoin payments go 'invisible' in Southeast Asia as crypto card business surges
StraitsX, a Singapore-based company, has seen rapid growth in its stablecoin card program, with a 40x surge in transaction volume and an 83x increase in card issuance between 2024 and 2025.
Scouting Future Saints: Missouri edge rusher Zion Young
Missouri edge rusher Zion Young is one of the draft's most underrated at his position and could add real production to the Saints defense.
After the 'War 2' debacle, Aditya Chopra is quietly working on a 'mysterious, timeless romantic saga'
After the 'War 2' debacle, Aditya Chopra's production house is working on a rom-com. The production house that has given us movies like 'Saiyaara', 'D.
Chris Kelly Opinion: A petition for better acting in politics and PR
“Memory, all alone in the moonlight/ I can dream of the old days/ Life was beautiful then…” – from “Memory,” by Andrew Lloyd Webber Successful theatrical productions achieve the “suspension of disbelief,” temporarily convincing audiences th…
The surprising science of quitting
Most of us are just one event away from resigning even though we probably should stay put
John Jacobs: Put students, not politics, first in Alabama classrooms…
We can, and should, get back to the basics of ensuring Alabama’s classrooms remain places where students come first. Our children deserve nothing less. |…
The geography of science
Scientific activity has historically been concentrated in a small number of advanced economies, but the global landscape of research is undergoing rapid transformation. Using data on 44 million publications from 1980 to 2022, this column examines how the geography of science has evolved along three dimensions: where research is produced, what topics it studies, and where it is consumed through citations. It documents a substantial shift in scientific production from traditional Western leaders s emerging economies. Yet scientific attention and knowledge diffusion remain uneven, revealing a tension between the global expansion of scientific capacity and the continued fragmentation of the knowledge system.
New Chattanooga business specializes in gun safety
Ginger Chandler stood at a panel of windows overlooking a vast production floor, where a small team of workers meticulously soldered together electrical components and assembled handguns.
Canadian business stalls over US trade deal jitters
STORY: The Canadian manufacturing hub of Windsor is home to thousands of small and specialized part makers and caters primarily to car companies and equipment manufacturers. The city thrives on close integration with Detroit, America's automotive capital, just across the river.That means it's also on the frontline of tariff and trade uncertainty with Canada's largest trading partner. JACKIE RAYMOND: "Even if we don't directly work with the automotive industry, we indirectly do."Jackie Raymond is co-owner of FASTSIGNS, a Canadian company that designs and installs custom business signs and graphics.The company is coming off its toughest year since the pandemic. Orders from its core automotive clients dried up.And while a new project brought some relief, the company says customers are placing smaller orders, demanding longer payment terms, and bargaining harder on prices.:: FileIt all points to uncertainty tied to the United States-Mexico-Canada Agreement, which is up for review this year. It's a deal U.S. President Donald Trump has repeatedly said he could scrap.:: Washington, D.C. / December 2, 2025TRUMP: "...and we'll either let it expire or we'll maybe work out another deal with Mexico and Canada...":: FileThe agreement - known as CUSMA north of the border - exempts most Canadian goods from U.S. levies.While Mexico has started formal negotiations with the U.S. over the deal's renewal, Canada has so far only held informal talks.RAYMOND: "I think the CUSMA is very, very important because it trickles down to every little business right down to your barber shop and your nail shop, which will affect all of our customers."The situation in Windsor reflects a broader unease facing Canada's economy, which contracted 0.6% in the fourth quarter. About 90% of the city's exports cross the border, often multiple times during production.Manufacturing accounts for nearly a quarter of employment in the Windsor-Essex region.Its chamber of commerce, which represents about 750 businesses, says companies paused investments, delayed production, and cut jobs at the height of the tariff uncertainty last year. :: FileWindsor partly regained its footing as Trump exempted USMCA-compliant exports from Canada from tariffs in March last year.But uncertainty still drags on business confidence and Windsor's unemployment level remains one of the highest among major cities in Canada.Local shops complain of lower traffic and restaurants report thinner crowds.And builders say the housing market – often among the first sectors to show strain from the knock-on effects of tariff uncertainties – is near a standstill.Brent Klundert of BK Cornerstone, a local real estate builder, said he laid off 13 of his 21 staff as sales and prices slumped last year. "And you know, when people are going to make the biggest investment of their life, they really want confidence in their job, in the longevity of their job in the economy itself. And people lost that due to the tariffs.” // “If we can get through CUSMA, if we can get through our trade agreements with the US, I think that that will add a lot of confidence into the marketplace that we've been lacking.”Since January Klundert has rehired 10 of his employees, hoping homebuyers would start coming back.So far, only a few have.
Del City Mayor steps down due to health issues
Del City Mayor Floyd Eason tells News 9 he is stepping down due to health issues.
Art Rooney on Rooney Rule: "The environment has changed"
The NFL has found itself in a DEI minefield.
Controversial star receiver named Philadelphia Eagles' most overpaid player
Earlier this month, star cornerback Cooper DeJean was named the Philadelphia Eagles’ most underpaid player by Brad Gagnon of Blecher Report. Gagnon recently released a list of every NFL teams’ most overpaid player, and for the Eagles, that distinction went to mercurial star wide receiver A.J. Brown. Brown has eclipsed the 1,000-yard mark in each of his four seasons in Philadelphia, but declining production combined with a huge contract and some distracting behavior has led Brown to being overpaid, at least in the eyes of Gagnon.
David Cross says stand-up specials aren't special anymore unless comics start breaking some rules
To make comedy specials special again, Cross says performers must break rules and take risks, rejecting slick, expensive productions that feel impersonal and phoned-in.
A conversation with Berthoud’s business community
The Berthoud Weekly Surveyor is inviting local business owners to join us for an open house at our office. This will be a relaxed, welcoming evening focused on conversation. A chance to connect, exchange ideas, and talk about what’s important to you and your business.
Trey Hendrickson was "looking forward" to playing with Maxx Crosby
Less than 24 hours after the Ravens' trade for Maxx Crosby fell through, the team agreed to terms with Trey Hendrickson.
African Content Moderators Have Worse Mental Health than Global Peers, Study Finds
A new study finds African content moderators report worse mental health than global peers, amid low pay, precarious work, and exposure to traumatic content.
Syracuse men’s lacrosse: Offense finding itself entering ‘second season’
Production is up as the lineup looks to have found some consistency for the first time this season.
Bringing SaaS to a wellness business
Wellhub CFO Bruno Annicq joined the company for the chance to make a big impact.
Entertainment Industry Veterans Launch Unified Production Platform (UPP)
Unified Production Platform (UPP) today announced its official launch, led by founder Mujeebur Rahmansaher and partners Greg Smith and An De Vooght—three ent...
On Opening Day, some Cubs fans lean into sports betting boom while others remain wary
Sports betting has exploded in Illinois since it was legalized in 2020. Fans heading into Wrigley Field on Thursday could gamble on their phones or at a sportsbook at the ballpark.
Seattle Public Theater’s ‘Hurricane Diane’ is a funny, pointed parody
Seattle Public Theater’s production of “Hurricane Diane” provides five of the best comic performances you are likely to see in Seattle.
New Congressional bill targets sports team relocations
More than 40 years after the Colts left Baltimore for Indianapolis like thieves in the night, those in a profession that enjoys nearly the same level of respect are trying to prevent it from happening again.
With Bears in mind, Sanders bill would offer up sports teams to city before 'billionaire owners' try to move
The Home Team Act would require an owner to announce that it wants to relocate a year prior, giving the community a chance to buy at "fair market value." Texas U.S. Rep. Greg Casar called it a "keep-the-Bears-in-Chicago bill."
US ramping up production of weapons critical for major war
From Tomahawk missiles to THAAD interceptor seekers, the US is massively increasing its production rates for key munitions amid stockpile concerns.
As political winds shift, this Louisiana renewable energy venture shoots for the stars
"We've spent years figuring out how to make wind blades lighter, stronger and cheaper — and we're set up at a facility that will allow us to expand quickly into production and shipping at scale. Now we're ready to apply those strengths to booming sectors of the economy."
Samsung Reportedly Drops Plans To Design Its Exynos 2800 On A Sub-2nm Process, Preferring Healthy Yields And Optimizations Over Cutting-Edge Lithography
Rather than raise unnecessary production costs, the Exynos 2800 will utilize Samsung’s new 2nm process to achieve better yields and optimizations
Meta and Google liable for social media harm to children’s mental health in landmark US case
Jury awards at least $3mn in damages with Instagram owner to pay the majority
Xiaomi's EV business defies industry slump with standout profitability
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Glyphosate: A story of science, risk, and nuance
In the summer of 2014, a California groundskeeper named Dewayne Johnson started noticing patches of raw, weeping skin spreading across his body. He had spent years applying Roundup, Monsanto’s glyphosate-based herbicide, for a school district, sometimes drenched in it when equipment malfunctioned. By 2014, he had a diagnosis: non-Hodgkin’s lymphoma. In 2018, a jury awarded him $289 million in damages, later reduced on appeal. Tens of thousands of lawsuits followed. The story hasn’t quieted down. It’s all over the internet, swinging between “this will kill you, buy organic” and “relax, you’re fear-mongering.” Some of that recent chatter stems from an Executive Order protecting glyphosate and its production, which set off intense infighting within the MAHA movement. Some of it reflects a deeper truth: Americans genuinely care about harmful chemicals in their environment (see poll below). And the conversation isn’t going anywhere, with a Supreme Court case involving Monsanto set for this April. Glyphosate (the active ingredient in Roundup) is one of the most widely used herbicides in the world. But does glyphosate cause cancer? And how much exposure is actually risky? With so much mistrust in institutions and corporations (and some genuine conflicts of interest), making sense of the actual scientific evidence is genuinely hard. Here is a translation of what the scientific evidence actually says. Does glyphosate cause harm? Glyphosate is an herbicide that kills most plants it contacts rather than targeting specific species. It works by blocking an enzyme pathway (EPSPS) that plants and many microorganisms need to produce essential amino acids. Without those amino acids, the plant can’t grow and dies. Glyphosate was first developed by Monsanto in the 1970s and became ubiquitous after the company introduced “Roundup Ready” crops in the 1990s. In 2024, Bayer removed glyphosate from residential Roundup-branded products due to litigation pressure. But today it is still the most widely used herbicide in the world. Farmers also discovered they could spray it directly on crops like oats, lentils, beans, and peas just before harvest to dry them out faster and make harvesting easier. Because of its widespread use, it’s obviously really important to understand if it’s harmful to humans. The key principle: The dose makes the poison The most important concept in toxicology is that “the dose makes the poison.” Sixteenth-century physician Paracelsus articulated what remains the foundational principle of toxicology: sola dosis facit venenum. Water will kill you if you drink enough of it. Aspirin saves lives at 81 milligrams and causes internal bleeding at higher chronic doses. So, at what dose is glyphosate poisonous? The LD50 in rats (the dose that kills half the test animals) is around 5,600 mg/kg body weight. Table salt is roughly 3,000 mg/kg. By that classic measure, glyphosate is less acutely toxic than salt. But some people are exposed to a lot of glyphosate through their work. And among the general public, there are many questions about low-dose, cumulative exposure from multiple sources over long periods. Does glyphosate cause health problems? Cancer Correlation maps are striking, with one analysis finding that 60% of counties that spray the most glyphosate have non-Hodgkin’s lymphoma rates above the national average. But correlation alone doesn’t establish cause, which is why animal and human studies matter. In animals: Rat studies are typically what most fear is rooted in, but most people don’t know the study details on the dosage given to rats. A pooled analysis of the 13 most rigorous rat studies found evidence that very high doses, around 55,000 times greater than typical food residue exposure, can cause certain cancers. In humans: One of the strongest studies followed 55,000 herbicide users over 20 years and found no overall increased cancer risk. There was one signal: among those with the highest use, rates of acute myeloid leukemia (AML) appeared elevated. A broader meta-analysis of 18 human studies also found no overall cancer risk, though a separate meta-analysis focused specifically on non-Hodgkin lymphoma found that people with high cumulative glyphosate exposure faced a 41% higher relative risk compared to those with low or no exposure. These human studies are observational studies (randomized controlled trials would be unethical), and meta-analyses are only as reliable as the studies they pool. But the story seems consistent: at very high exposure levels, there may be some cancer risk. But that’s about as far as the science currently takes us. Emerging research: gut and reproductive health Gut: Because glyphosate targets a pathway that exists in some gut bacteria, scientists have questioned whether it could affect the microbiome. In mice, a 2023 University of Iowa study found that glyphosate altered gut bacterial composition and raised markers of intestinal inflammation. A 2024 systematic review found similar patterns: disrupted gut bacteria and problems with the mucus layer that protects the intestinal wall in mice. Whether this translates to humans is an open question. The human gut is highly variable and resistant, and we don't yet have strong studies confirming the same effects in people. Reproductive health: Animal studies have found that glyphosate-based herbicides can interfere with reproductive hormones, including disrupting egg cell development in mice and reducing the number of eggs available in sheep’s ovaries. However, the doses used in these experiments were high, so it’s not yet clear whether the same effects would occur in humans. On the human side, a 2021 pilot study led by Mount Sinai researchers tested urine samples from pregnant women across the U.S. and found glyphosate in 95% of them. The study also found a possible connection between higher glyphosate exposure during pregnancy and a subtle physical difference measured in female newborns. That said, some connections weren’t statistically reliable and this was a small study. The researchers themselves said more and larger studies are needed before drawing firm conclusions. What do regulators say about glyphosate safety? In 2015, the International Agency for Research on Cancer (IARC), part of the World Health Organization, classified glyphosate as "probably carcinogenic to humans" (Group 2A). The classification is worth taking seriously. But, there’s an important distinction: IARC classifies hazard, meaning the potential to cause harm under some conditions. It does not assess risk, which accounts for actual exposure levels and the real-world probability of harm. The U.S. EPA, the European Food Safety Authority, Health Canada, and regulatory agencies in Australia and Japan have all concluded that glyphosate is “unlikely to be carcinogenic to humans” at realistic exposure levels. They’re asking a different question: given how much of this people actually encounter, what is the probability of harm? Your actual exposure is what determines your actual risk. What does glyphosate mean for your daily life? At the grocery store: Food residues are small. The EPA’s acceptable daily intake is 1.75 mg/kg of body weight per day. To hit that threshold from oatmeal alone, a 150-pound adult would need to eat roughly 50 pounds of oats every day. But this calculation addresses only one pathway (food), and we don’t yet have robust tools to measure people’s actual total exposure. If reducing exposure matters to you, organic certification prohibits synthetic herbicides, and organic oat products generally test at lower or undetectable levels. Either way, a diet rich in whole grains, conventional or organic, is far better for your health than one that omits them out of fear of residues. On the farm: Occupational exposure is orders of magnitude higher than consumer exposure. Farmers and farm workers who mix, load, and apply glyphosate-based herbicides, especially without protective equipment, face meaningfully different risk profiles. Proper PPE isn’t optional. Integrated weed management strategies that rotate chemical modes of action are also worth taking seriously, both for health and for long-term effectiveness. If you live near a farm: Spray drift is real. Concentrations near field edges can spike during and after application, particularly on windy days. This is an area where I think public health could really step up and empower rural communities with buffer zones, rather than placing the onus on individuals. But for now, knowing your local agricultural calendar and keeping windows closed during application are the first steps. Bottom line Dewayne Johnson was exposed to glyphosate at levels most people will never encounter, and a jury decided he deserved compensation. That outcome is not evidence that the oatmeal in your pantry is dangerous. But it is a reminder that the dose, the context, and the person doing the exposing all matter enormously. Glyphosate is a chemical tool with benefits, trade-offs, and genuine open scientific questions. Learning to hold that complexity without collapsing into panic or dismissal is, honestly, one of the most useful and hardest things to do in navigating modern health science. Love, YLE Your Local Epidemiologist (YLE) is founded and operated by Dr. Katelyn Jetelina, MPH PhD—an epidemiologist, wife, and mom of two little girls. Hannah Totte, MPH, is an epidemiologist and YLE Community Manager. YLE reaches more than 425,000 people in over 132 countries with one goal: “Translate” the ever-evolving public health science so that people will be well-equipped to make evidence-based decisions. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe
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