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How a UVA Darden Executive Program Alumnus Helped Bring the Rotunda to Taipei
During America’s Bicentennial, a Taiwanese university president found inspiration in UVA’s Rotunda. Fifteen years later, a Darden Executive Program alumnus helped carry that vision across the Pacific.
AMC Entertainment (AMC) Is Down 8.7% After Equity Raise To Retire 2027 Notes And Fund Upgrades
In late June 2026, AMC Entertainment Holdings, Inc. completed a registered direct equity offering of about US$200.03 million and moved to fully redeem US$125.47 million of its 6.125% Senior Subordinated Notes due 2027 at par plus accrued interest. The company plans to use the remaining proceeds to bolster cash reserves and fund growth-oriented upgrades across its theatres as early as this autumn. Next, we’ll explore how using fresh equity capital to retire higher-cost debt and invest in...
BlueCrest warns UK is bad for business after losing £200mn tax battle
Investment firm says country ‘no longer a serious contender’
Small Businesses Inherit Big Business Money Problems
Large corporations and small businesses aren’t the same. The most obvious difference is sheer scale, but the knock-on effects of that scale have
Citadel Says Credit Unions Can Compete for Bigger Business Relationships
Small business banking has entered a period of reassessment as business owners look beyond rates and fees toward financial partners that can combine
The new Pac-12 Conference officially launches with the addition of seven full-time members
July 1, 2026 — Today, seven new full-time member institutions officially join the Pac-12 Conference, including Boise State, Colorado State, Fresno State, Gonzaga, San Diego State, Texas State and Utah State. With the additions, the new Pac-12 features nine full-time members and is set to compete in its first season with the 2026-27 campaign. The league also officially welcomed 12 new affiliate members today across five Olympic sports, including baseball (Dallas Baptist), men’s soccer (Cal Baptist, Cal Poly, UC Riverside, UC San Diego), women’s gymnastics (Southern Utah), women’s swimming (Cal Baptist) and wrestling (Air Force, Northern Colorado, North Dakota State, Northern Illinois, South Dakota State). In addition to official member admissions and the launch of the new Pac-12, and amid celebrations across new member communities, the league also made a series of other announcements related to its basketball tournaments, its official sports sponsorship and championships and a special edition content series in promotion of its first football season.
COVID Loans Were Meant For Businesses. DOJ Says $170K Went To His Personal Account
A North Carolina man has pleaded guilty after federal prosecutors said he obtained more than $170,000 from COVID-era business loan programs using false applications. Phillip ... Read More
Running with purpose: SAU alumni build a business and a ministry one race at a time | News
For Briston and Carley Rains, running is more than a sport. It is a career, a calling, and a ministry. The two Southern Arkansas University graduates are the owners of Texas Outlaw Running…
“Dutton Ranch” hires new boss for season 2 after moving on from creator
A "Justified" alum is taking over the "Yellowstone" spinoff series.
Dragon Age Lead Writer Condemns AI As A 'Virulent Plague'
David Gaider doesn't hold back when explaining why genAI is so bad for games development
Public Health steps up to meet community needs
Public Health continues to increase its presence in the community.
NotebookLM adding Short Video Overviews with Nano Banana 2 Lite
Google today announced Nano Banana 2 Lite and preview availability of Gemini Omni Flash, as well as NotebookLM Short Video Overviews.
Chicago Business Activity Cooled in June
The Chicago Business Barometer, compiled by MNI Indicators, slipped to 56.7 from 62.7 in May, but still beat expectations.
Supreme Court upholds state transgender sports bans
In the latest of a string of losses for LGBTQ rights, the high court allowed states to bar transgender athletes from girls’ and women’s sports.
In St. Pete, activists speak out for science
In a small St. Petersburg demonstration, scientists and their supporters fight back against government cuts to research.
The Latest: Supreme Court is set to rule on Trump’s challenge to birthright citizenship
The Supreme Court will rule on the constitutionality of President Donald Trump’s order on birthright citizenship declaring that children born to parents who are in the United States illegally or temporarily are not American citizens.
A milestone for Zooniverse
The University of Minnesota-connected citizen science platform logs its one billionth contribution to scientific knowledge.
New BioShocking Attack Tricks AI Browsers Into Leaking User Credentials
LayerX says BioShocking used indirect prompt injection to trick six AI browsers into copying credentials from signed-in accounts.
'Staying away from the middle will be hardest': Sachin Tendulkar's emotional message to Ben Stokes after retirement
Sachin Tendulkar led heartfelt tributes to Ben Stokes following his retirement from international cricket. Tendulkar lauded Stokes' fearless approach, match-winning ability, and inspirational leadership, calling him one of England's finest all-rounders and captains. Stokes, who bowed out after a Test series loss, expressed contentment with his decision, citing years of physical and mental demands as the primary reason for stepping away.
Oracle E-Business Suite Flaw CVE-2026-46817 Actively Exploited in the Wild
Oracle E-Business Suite vulnerability CVE-2026-46817 (CVSS 9.8) is being actively exploited in the wild despite Oracle’s recent patch release.
New York Yankees’ Jazz Chisholm Jr. Exits Game Against Tigers
The New York Yankees have been struggling in recent games, and their ballclub is continuing to spiral. In the fourth inning, Jazz Chisholm Jr. collided with Jasson Domínguez, ultimately knocking Chisholm to the ground. Status alert: Jazz Chisholm Jr. leaves game Monday.pic.twitter.com/5XyTh98wIX — Underdog MLB (@UnderdogMLB) June 30, 2026 Chisholm exited the game following the […] The post New York Yankees’ Jazz Chisholm Jr. Exits Game Against Tigers appeared first on HEAVY.
Biology alumni receive honor for undergraduate paleontology research
Julia Zottola ’26 and Sofia Corsico-Sánchez ’26 earn recognition from the Association for Women Geoscientists and the Paleontological Society
Nancy Pelosi, Connie Chan condemn Scott Wiener harassment incidents
Chan and Pelosi did not sign onto a letter condemning the incident captured in a viral video, but spoke out against harassment in statements to the Chronicle.
Sony Spurs $1,000 PlayStation 6 Rumors
Rumors of sky-high next-gen consoles have been floating around for about as long as the next-gen consoles have been confirmed as in development, but it seems as though Sony CEO, Hideaki Nishino has all but confirmed $900+ pricing for the PS6 in a recent Q&A session following an official Gaming & Net...
The Entertainment Community Fund Reveals New Board of Trustees Appointments and Leadership Additions
The Entertainment Community Fund, formerly The Actors Fund, has revealed four new Board members, including one returning member, as well as new appointments to its Western Council and the Actors Fund Home Board of Trustees.
WhatsApp is Finally Getting Usernames to Help Keep Phone Numbers Private
WhatsApp is rolling out username reservations globally, letting users reserve unique names before the privacy feature launches later this year.
How The Nitro Bar became a booming coffee business
As part of the series Women Mean Business, NBC News' Savannah Sellers spoke with The Nitro Bar co-founder Audrey Finocchiaro about building a fast-growing coffee brand, expanding to New York City, and turning a bold idea into a thriving business.
Supreme Court declines to hear Trump appeal of E. Jean Carroll sexual abuse verdict
The Supreme Court Monday declined to take up an appeal from President Donald Trump over a $5 million verdict and finding that he sexually abused and defamed E. Jean Carroll, a decision that means the president will now have to pay the magazine columnist.
How Sports Other Than Football Shaped Garrett Wilson’s Creativity
Growing Up, the WR Also Played Basketball and Did Gymnastics
America @ 250: Alex Wysocki asks, ‘Are short-term political gains worth giving up the big picture?’
Alex Wysocki is a television producer, filmmaker, husband and father of three. He and his wife Abigail moved to Champaign during the COVID-19 pandemic and are raising their family here.
Add Lynn Bartels to Colorado’s roll call of legends
A few weeks after the Rocky Mountain News shut its doors forever in 2009, more than 600 Republicans gathered for the state party’s annual Centennial Dinner. Lamenting the historic significance of the loss of one of Colorado’s great daily newspapers, the state chairman noted the presence that evening of former Rocky political reporter Lynn Bartels […]
Trafalgar Entertainment to Acquire The London Theatre Company
Trafalgar Entertainment announced the acquisition of The London Theatre Company, adding The Bridge Theatre and King's Cross Venue to its growing portfolio of entertainment venues.
Notable Rutgers grads and former students
Some notable Rutgers alumni include James Gandolfini, Chris Christie, Eric LaGrand and more.
BT and Verizon to create new international business in $625mn deal
New 50:50 venture will be milestone in UK group’s strategy of refocusing on its domestic operations
These @USMNT kits are strictly an athletic-fit situation
These @USMNT kits are strictly an athletic-fit situation
We turned 80-year-olds into trained health monitors to save lives and boost senior dignity
As a career geriatrician, I’ve long known that some of society’s finest minds are being underappreciated while living in senior communities. So I helped to develop a new health program to help put older adults on the watch as health monitors.
Nintendo Switch eShop latest sales: lowest prices ever for TMNT: Shredder's Revenge, Tomb Raider 4-6, Witcher 3, more
A bunch of new sales are up and running on the North American Nintendo Switch eShop. These include the lowest prices ever for Teenage Mutant Ninja Turtles: Shredder’s Revenge, Tomb Raider 4-6 Remastered, The Witcher 3: Wild Hunt, and more. Here’s the full roundup: – .hack//G.U. Last Recode – $9.99 (was $49.99) – A Boy and His Blob – $6.74...
New academic leader ready to get to business in Morgantown
New Provost Beverly Wendland officially begins her post July 1.
Stetson Bennett dealing with ‘business side’ of NFL in QB competition with Rams
Former Georgia quarterback Jake Fromm provides perspective on the challenge Stetson Bennett faces competing with Ty Simpson on the Los Angeles Rams.
NEW Pirates Entertainment CONFIRMED for Mickey's Not-So-Scary Hallowee...
There's a new offering coming to Mickey's Not-So-Scary Halloween Party this year!
Israel missing out on global life sciences recovery
IATI's annual report for 2025 portrays general stagnation in the Israeli industry. with one or two bright spots.
Why does metal stick together in space?
If you push two metal plates together on Earth, nothing happens. In space, they can fuse into one. Here's why.
Read Michener’s ‘Centennial’
If you’ve been reading my columns, you’ve noticed I’m basically illiterate. I blame my dyslexia and public education, but my Olympic-level laziness could be the driving factor. Anyway, I basically can’t read (and, still, I graduated from CU Boulder, so another endorsement of public higher education). So, for me to recommend a book is like […]
South Korea's World Cup Exit Stuns Football, Entertainment Industries
South Koreas World Cup Exit Stuns Football, Entertainment Industries Hong Myung-bos squad finishes third in group; entertainment programs face awkward invitations amid lack of inspiring content
2026 World Cup Group J: Wild Austria-Algeria tie locks Iran out of knockout rounds
Here's how everything shook out in Group J of the World Cup.
UAPB School of Business and Management celebrates class of 2026
The School of Business and Management (SBM) at the University of Arkansas at Pine Bluff recognized the achievements of its graduating Class of 2026 during its annual Graduates Banquet recently at the STEM Conference Center. The event, coordinated by Cynthia Sims, SBM project/program specialist, brought together students, faculty, administrators, alumni, family members and supporters to […]
Israeli politicians lash out after Netanyahu announces intention of 'broad national government'
During the press conference, Netanyahu condemned unnamed forces which "want to cause a rift in the people, want to aggravate and deepen the misunderstandings and disagreements and rifts within us."
Gunnar gives back: O's shortstop surprises local kid with specialized cleats
BALTIMORE -- The story of 11-year-old Declan Lefevre’s youth baseball career is inspirational. When Declan was about 4 years old, a doctor noticed his legs were different lengths. And it wasn’t something he would grow out of, either, which is something his parents -- father Jeff Lefevre and mother Nichole
Burcum: Sanford Health got what it wanted. Now comes the moment of truth.
From columnist Jill Burcum: The South Dakota health system has spent a decade trying to crack the Twin Cities health care market. With the North Memorial deal, it now has a chance to prove itself.
Yankees Birthday of the Day: Eric Reyzelman
Celebrating an unheralded Yankees prospect on his 25th birthday!
Lawsuits filed against Pharr immigration-related business after filing unauthorized asylum claims
Two families have filed lawsuits against Pharr-based Ferrer Public Services, claiming the business filed unauthorized asylum applications that put their immigration status at risk.
Colts roster preview: AJ Haulcy garnering attention during offseason
With training camp off in the distance, we will be previewing each player on the Colts' 90-man roster. Up next is S AJ Haulcy.
Fallout from USMNT loss to Turkey and previewing the Mbappe-Haaland clash
On today’s show, we look back at the United States’ final group stage match against Turkey and evaluate their readiness for the Round of 32. Manchester City insider Sam Lee joins us to preview the tournament’s first true superstar heavyweight clash as Kylian Mbappe and France square off against Erling Haaland and Norway in a battle for Group I supremacy. Plus, The Athletic’s Jay Harris is back in the studio to break down the latest bracketology, advancement percentages, and qualification permutations for Groups G, H, and I using The Athletic’s World Cup Tracker.
Former Giannis Role Players Now On Milwaukee Bucks Trading Block
The Milwaukee Bucks are turning the page to a new chapter in their franchise following the trade of Giannis Antetokounmpo to the Milwaukee Bucks. Along with opening a new era, the Bucks are also looking to move on from some of their role players during the team’s Giannis phase. Among them are Kyle Kuzma and […] The post Former Giannis Role Players Now On Milwaukee Bucks Trading Block appeared first on HEAVY.
California is in for a summer of wild billionaire spending
OPINION: With competing tax measures on the ballot, California billionaires will be spending like... billionaires, political columnist Joe Garofoli writes.
Coldwater Creek flooding impacts business at 'Bob's Canoes' in Milton
MILTON, Fla. -- River levels are dropping back to normal in Santa Rosa County after the remnants from Tropical Storm Arthur came through.
NFL stadiums swapped turf for grass ahead of 2026 World Cup. George Kittle thumping for permanent change: 'Clearly we know it's possible'
New for MNSSHP 2026: Captain Jack Sparrow Leads Pirate Entertainment in Adventureland
Captain Jack Sparrow joins MNSSHP 2026 in Adventureland with a new pirate entertainment act. The Rusty Cutlass band has not appeared on any confirmed 2026 lineup yet.
We have an epidemic of political violence in this country: National Review columnist
National Review columnist Caroline Downey discusses growing political violence and criticizes Illinois Gov. J.B. Pritzker for his remarks about the Chicago cross-burning incident.
We have an epidemic of political violence in this country: National Review columnist
National Review columnist Caroline Downey discusses growing political violence and criticizes Illinois Gov. J.B. Pritzker for his remarks about the Chicago cross-burning incident.
Essentia again ranks among Minnesota's best for quality care
Minnesota Community Measurement (MNCM) — a statewide resource providing timely, comparable information on healthcare quality, costs and equity — once again ranks Essentia Health as a quality leader in its annual Health Care Quality Report.
Manufacturing business cuts ribbon in Putnam County, set to bring 120 jobs to area
The operation is a joint venture between global engineering group Sandvik and mining company Alpha Metallurgical Resources.
Mauricio Pochettino reportedly offered contract extension to coach USMNT for another World Cup cycle, through 2030
Minuteman Press Franchise Owner Dave Forster Reflects on 40 Years in Minneapolis
MINNEAPOLIS, June 26, 2026 (GLOBE NEWSWIRE) -- Dave and Sandy Forster are the owners of Minuteman Press in Minneapolis, MN since February of 198...
After 80 Years, Mathematicians Give Famed ‘Erdős Method’ an Upgrade
Decades ago, Paul Erdős used randomness to illuminate the vast and weird world of networks. Now mathematicians are making his technique even more powerful.
From The Sports Desk: The U.S. lost, but also saw return of star Christian Pulisic
The Americans may have lost their final group stage. But Pulisic, who had been nursing a calf injury, returned to action. He’s back just in time for the start of the knockout round.
KXNO layoffs leave Iowa sports community too quiet
This week's layoffs of local sports radio talkers leaves our sports community worse off, columnist Travis Hines writes.
Ben Wood, longtime three-dot columnist known as ‘Mr. Show Business,’ dies at 94
Ben Wood, a multifaceted copy editor, food and entertainment writer, and three-dot columnist for the Honolulu Star-Bulletin and Honolulu Star-Advertiser for almost 50 years, died June 19 after several years of declining health. He was 94.
'It's business': 2027 5-star CB on choosing Texas over Texas A&M
2027 5-star CB John Meredith "loves A&M to death" but made a reported business decision in choosing the Texas Longhorns.
Online retailer John's Crazy Socks relocates to Huntington in effort to turn around business
The company's core mission is to create employment opportunities for people who face barriers to work because of disabilities.
Sweden: European Social Rights Committee calls for an end to Sweden’s two-tier healthcare system
Amnesty International welcomes a landmark decision by the European Committee of Social Rights finding that Sweden breached the right to health without discrimination.
World Cup 2026: USMNT stunned by Türkiye in stoppage time, losing perfect group stage run
USA vs. Türkiye score, live updates: USMNT finishes group play before knockout match with Bosnia and Herzegovina
World Cup 2026: Christian Pulisic won't start for USMNT's group stage finale against Türkiye
Serious statin side effects on muscles are extremely rare, new research confirms
Scientists created a new tool to help doctors predict a patient’s risk of severe muscle problems from taking a statin.
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Kurt Zellers Steps Down as CEO of the MN Business Partnership
The former legislator’s tenure in this key role lasted less than three years.
Sofia Elverdin Selected as Co-Recipient of the Best Dissertation Prize From the American Political Science Association’s Women, Gender and Politics Section
Sofia Elverdin, assistant professor of politics at Washington and Lee University, was recently selected as a co-recipient of the American Political Science Association’s (APSA) Best Dissertation Pr…
Game On Retro owner plans entertainment empire expansion, Coram movie theater transformation
Plans include opening a new arcade, store and transforming a shuttered movie theater in Coram.
Poppi founder speaks about building a billion-dollar soda business
Allison Ellsworth, the founder of the viral soda brand Poppi, sits down with NBC News' Savannah Sellers to discuss how she turned a personal health issue into a billion-dollar cultural phenomenon.
🇺🇸 Y! Sports AM: Why not U.S.?
The USMNT, who play their final group stage match tonight, have given fans reason to believe in their status as contenders.
Ensuring health for Special Olympics athletes
University of Minnesota healthcare students across many disciplines are helping to provide health screenings for athletes competing in the 2026 Special Olympics USA Games.
ADUSA tapped a former Amazon exec to helm its business. What does this mean?
The grocery company’s nominee for the top role may raise some eyebrows given Amazon’s brick-and-mortar track record, but Claire Peters' appointment could be the key to further omnichannel growth.
Folarin Balogun and USMNT Transfer Updates
Hosts Tamerra Griffin and James McNicholas break down a massive six-match World Cup slate as group stages reach their climax. Soccer insider David Ornstein joins the show to discuss the escalating transfer market buzz surrounding USMNT star Folarin Balogun and Tottenham’s Lucas Bergvall. Plus, the team highlights The Athletic’s interactive World Cup Tracker with Jay Harris to map out the complicated qualification pathways for Group A, B, and C. Can the USMNT line up a favorable Round of 32 matchup? Senior Editor Hannah Vanbiber also dives into the debate surrounding Jeremy Doku’s...
What's new to streaming this week? (June 26, 2026)
What’s new on Netflix, Prime Video, Hulu, and more? We've got you covered.
Walmart Business Targets the Invisible Work Slowing Small Business Down
Running a small business can take up a big chunk of its owner’s time. Even something as simple as ordering the breakroom snacks each month can add up, and
The Painting That Is Still on Trial in South Korea: How the unending Korean War became a permanent excuse to criminalise expression
By Boram Jang, East Asia Researcher at Amnesty International In a Seoul courtroom in March this year, a prosecutor read out charges against Jeon Seung-il, a former art student, from an indictment first written in 1989. The language had not changed, nor had the charges. Thirty-seven years later, only the young defendant had grown old. In 1989, he was 23 years old in a South Korea still shaped by decades […]
Sen. Van Hollen: Trump is saying he ‘doesn’t give a damn’ about people who can’t afford housing
The biotech founder asking why good science gets stuck
As an undergraduate, Alinta Furnell led student societies, pitched startup ideas and built biotechnology ventures. Now, the UNSW alumna is investigating one of innovation’s biggest challenges – why so many scientific breakthroughs never make it beyond the lab.
Julian Edelman's blunt advice for Patriots with Christian Gonzalez
Julian Edelman shared his thoughts on the ongoing contract situation between the Patriots and star cornerback Christian Gonzalez.
Scientists observe water switching between 2 different molecular structures, boosting decades-old theory
For decades, scientists suspected water secretly behaves like two different liquids. A new AI-powered study has finally caught it happening at the molecular level.
Overwatch Fans Revolt Over New Skins That Cost Too Damn Much
The new ‘Ultra’ skins include visual and audio effects, but is that enough?
Entertainment Listing: June 24
Wednesday June 24 Little Nashville • Marion Bingo, 6 p.m. – 9 p.m. PK’s • Carbondale Trivia, 8 p.m. – 11 p.m. Advertisement Thursday June 25 PK’s • Carbondale Ethan Stephenson Band, 9 p.m. Little Nashville • Marion Chris Chamness, 6 p.m. – 9 p.m. Sunset Concert, New Era Events Plaza The Way Down...
Day Two of Competition Highlights Athletes Across Multiple Sports
The second day of competition at the 2026 Special Olympics USA Games was cut short due to inclement weather, but not before some memorable moments. Before outdoor events were halted, athletes showcased speed on the track, excitement and enthusiasm at gymnastics, and pride on the football and soccer fields. Even as an athletics athlete from Special Olympics Southern California lost his shoe, he managed to win the race.
Editorial | Brooklyn coffee shop’s snub of Congress member shows politics boiling over in NYC
He was out on Sunday campaigning in Brooklyn for re-election to his Congressional seat when he paid a visit to Poetica Coffee. Goldman said the staff politely
Financing the Future: Leaders Make the Investment Case for Women's, Children's and Adolescents' Health
With development assistance declining and health systems under growing strain, leaders at Africa Health ExCon called for a shift from fragmented financing to integrated, sustainable investment in women’s, children’s and adolescents’ health. Discussions highlighted domestic financing, private sector engagement, service integration and climate-resilient health systems as pathways to greater impact.