SCROLL NEWS / DISCOVERY
Search headlines
Find the stories shaping the conversation.
Results for " orr " 4,616 found 🔀 AI-powered Shuffle
Mayor Mamdani, NYC Health + Hospitals break ground on $255M River Commons, bringing 328 affordable affordable homes to the South Bronx
The city has broken ground on River Commons, a mixed-use development in Morrisania that will bring 328 affordable and supportive apartments, an expanded
'American Horror Story' reveals 'Love Story' heartthrob's blond transformation
'American Horror Story' reveals 'Love Story' heartthrob Paul Anthony Kelly's blond transformation for season 13.
Chapin is set to get a slate of new restaurants and businesses. Check out where
The town of Chapin noted that several new restaurants and business are slated for a growing corridor.
Ice, Ice, Maybe? Scientists Are Trying to Regrow Ice in the Arctic With Simple Tech
Arctic sea ice is disappearing at a worrisome rate. What if there were a way to slow that down?
Are the 49ers better or just a little bit different?
The 49ers added Mike Evans and Raheem Morris, but are they better?
How 'Bad Santa' brought naughty Billy Bob Thornton onto 'Landman'
If you've ever thought that you'd seen Billy Bob Thornton's Tommy Norris before, you're jolly right. The "Landman" central character is the spiritual cousin to Thornton's infamous role as Willie
Iowa Business Council projects positive six-month economic outlook
The Iowa Business Council has released its second-quarter Economic Outlook Survey for 2026, showing member expectations for sales, capital spending and employment remain positive for the next six months despite a slight overall decline from the previous quarter. The survey’s overall economic outlook index sits at 64.81 points for the second quarter, a decrease of […]
Concern Mounts About Rumored ‘State Of Decay 3’ Cancellation At Xbox
Xbox fans are now worried about reports that State of Decay 3 may be cancelled, despite recent previews, ahead of big layoffs.
"We're talking about at least half a decade of horror": former Exodus lead explains why he wasn't keen on doing a Baldur's Gate 4 despite Hasbro offering the chance
After Larian opted against a Baldur's Gate 4, Hasbro asked Archetype Entertainment head James Ohlen if he fancied a crack at it and he wasn't keen.
What Norris Center in Naples offers 2 years after Playhouse exit
Two years after Gulfshore Playhouse's departure from the Norris Community Center, the venue's event calendar is full with broader entertainment offerings.
World Cup 2026: Why England and Thomas Tuchel should be worried about DR Congo ahead of last-32 clash
El Boletín newsletter: An earthquake shakes Venezuela’s political reset
Our correspondent in Caracas reports on how disaster is testing an already fragile country
Oil markets move from fearing shortages to worrying about surpluses
Global oil supply recovery eases shortage fears as Brent crude falls to $73. Wall Street is lowering forecasts amid demand concerns.
Fired FTC commissioner speaks to OutFront as Trump touts Supreme Court ‘big win’: ‘we should be worried’
What to stream: ‘Enola Holmes 3,’ Madonna’s new album and ‘Zorro’
"Enola Holmes 3" and a new album from Madonna are some of the new television, films, music and games headed to a device near you.
2 New Order Members Step Away From Touring Due to Health Reasons
New Order announced Monday that Stephen Morris and Gillian Gilbert will not be joining their show at Primavera in Chile in November.
Netflix and Superheroes Are Having a Rough Stretch on Streaming....
(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) I have a quick prediction before we start today’s article: You might see this data in future news articles. Not my specific charts or analysis, but the core trend I’ve been monitoring—Netflix is having a lackluster Q2—will become inescapable. Often, folks want to know “What does the data say?” Well, that’s what it says. I haven’t seen this analysis hit the trades really yet, but I have a feeling some other outlets are going to start making this case soon. Remember, you read it here first. You probably have read about the problems facing superhero films at the box office this weekend. Well, this week, I explore whether superheroes are dying on TV as well! And the data says: definitely maybe! We have a lot to cover in today’s Streaming Ratings Report, which covers the two weeks of 18-May and 25-May. Today, I’m just looking at TV, like Netflix’s disappointing Q2, superhero shows underwhelming, a few TV shows dropping off the charts, The Pitt finally ending its epic run on the viewership charts (and whether “view counts” change its status as one of the biggest shows of all time), all the flops, bombs and misses, and a whole lot more. Tomorrow, I’ve got a great rundown of the film side of things. Let’s dive right in! (Reminder: The streaming ratings report focuses on the U.S. market and compiles data from Nielsen’s weekly top ten viewership ranks, Luminate’s Top Ten Data, Showlabs, TV Time trend data, Samba TV household viewership, company datecdotes, Netflix hours viewed data, Google Trends, and IMDb to determine the most popular content. While most data points are current, Nielsen’s data covers the weeks of May 18th to May 31st, 2026. You can find a link to my terminology here.) Subscribe Television - Netflix’s Q2 Slump Continues Having analyzed streaming ratings for going on half a decade, I have learned to trust my gut, but I’m always relieved when I can find actual data to back it up. For example, after a string of very popular shows like Stranger Things, Bridgerton, The Lincoln Lawyer and The Night Agent came out, week after week, in January and February, my gut wondered if Netflix had enough new and returning TV shows to sustain them throughout the year. Since then, Netflix’s post-March slate of shows has not impressed me. This week seemed to feature a potential new hit, but then, like a classic Duffer Bros. TV show, there was a twist. I speak of The Boroughs, Netflix’s latest (and last) Duffer Bros. produced show. The pitch is “Stranger Things with older actors”. And it topped the Nielsen charts: With just two weeks of viewership, The Boroughs would have been a top 25 debut show last year: But here’s the twist: Netflix has already cancelled The Boroughs! What happened? Likely a few things. First, the show didn’t do as well globally as it did in the US. As What’s on Netflix showed, it lagged behind several other shows that got cancelled. Second, its completion rate was likely low; after an initial burst of interest, it quickly dropped off on the Samba TV and Luminate charts. Third, the Duffer Bros. left Netflix for Paramount, and that may have factored into Netflix’s decision here. (Though I tend to believe that if a show is doing well, Netflix would have kept greenlighting seasons.) Still, just because I can explain why Netflix may have cancelled this show doesn’t mean I’m justifying it. In particular, as I’ve noted before, Netflix is losing a lot of their bigger shows as they reach their natural ends, and they need to replace those shows. This show had the hallmarks of a big new genre show, and it’s their biggest hit of the last few months (in the US at least), but now it’s done. Netflix’s other show this week—The Four Seasons, the second season of the “hit” show from last year—definitely disappointed. Its sophomore season had about half the viewership of the first, only 12.7 million hours. It also only had a two week run on Samba TV, and its numbers were all down on Luminate too. In other words, even with two successes, the Q2 slump for Netflix looks real: I could add to the list of disappointments: Both Lord of the Files and Man on Fire had short runs on the Nielsen charts. Running Point’s sophomore season also opened to about half its viewership, similar to The Four Seasons. A Good Girl’s Guide to Murder’s second season—see below—didn’t even make any of the three viewership charts I track, unlike the first season. Netflix is absolutely having a dismal second three months of 2026. If this Nielsen data is any indication, and I think it is, I think this will show up in Netflix’s engagement report, and maybe even their financial outcomes. And the rest of June doesn’t look much better. We have two hit shows coming back—Sweet Magnolias, one of their quietest big shows, and Avatar: The Last Airbender, a big hit for them in 2024—but the other big swings are limited series crime thrillers i.e. no future season potential. Like I said above, sometimes when I uncover a juicy nugget like this, other outlets end up writing very similar articles mimicking the data without credit. We’ll see if that happens this time! Share Television - The State of Superhero Shows on Streaming When I first heard the pitch for Spider-Noir—a Sony TV show on Prime Video that binge-released eight episodes first on MGM+ then on Prime Video two days later—I had my doubts. It’s a live-action Spider-Man show set in the 1930s, starring Nicholas Cage, based on a cameo of a character in Spider-Man: Into the Spider-Verse. No, seriously, that’s the pitch. That could either go terrifically well or horribly wrong. Great because, Spider-Man. He’s the biggest superhero we have. I’ve seen tracking numbers that put the new _Spider-Man: Brand New Da_y as the blockbuster of the year and initial pre-sales back that up. And yet this Spider-Noir pitch feels very esoteric. (Also, the eight-episode binge release feels very “Amazon copying Netflix” again.) So what’s the data say? And what does this say about the future of superhero shows?
Slotkin Joins Michigan Delegation Urging Small Business Administration to Approve Disaster Declaration
WASHINGTON, D.C. — U.S. Senator Elissa Slotkin (D-MI), Member of the Homeland Security and Governmental Affairs Committee, joined members of the Michigan Congressional Delegation in urging the Small Business Administration (SBA) to support Michigan Governor Gretchen Whitmer’s request for an administrative disaster declaration following the severe thunderstorms, tornadoes, high winds, large hail and torrential rainfall across the state in April. […]
South Bay History: Del Amo Financial Center spotlighted Torrance’s thriving 1960s business community
The Del Amo Financial Center had its official grand opening on Sept. 20, 1967.
‘We have to have a big tent": Why this top Democrat says he’s not worried about primary wins by Democratic Socialists
Nintendo has suddenly announced a new Direct livestream for tomorrow
Whether you are a kid or a squid, you can tune in for more details on the single-player adventure game.
Resident Evil Veronica Finally Gives Claire Redfield Her Due – the Horror Series’ Most Ignored Character Deserves the Spotlight
Despite being in plenty of spin-offs and crossovers, Claire Redfield is in barely any of the mainline Resident Evil games. After a long time away, RE Veronica is finally set to give Claire her due.
Milei Taps Lifetime Politician to Lead His Cabinet After Scandal
Argentine President Javier Milei tapped a seasoned politician he once openly insulted on the campaign trail to become the fourth cabinet chief of his government plagued by corruption scandals.
Morris rides into orange and purple western town with unfinished business
In the '“Wild West” phase of college football, returning offensive coordinator Chad Morris is making a new mark at Clemson.
PPDS Brings 'Limitless' TV Entertainment To Historic 5 Star Bellevue Syrene Hotel With Philips MediaSuite
PPDS, the exclusive global provider of Philips Professional Displays, has announced that its Philips MediaSuite TV range has been chosen to deliver seamless access to a virtually limitless world of | Delivering modern luxuries to the 18th century hotel in Sorrento, Philips MediaSuite TVs with cast built in are now bringing seamless access to millions of movies, TV shows, games, and streaming apps to guests at one of Italy's most prestigious and exquisite hospitality destinations.
Iraqi Officials Arrested in Green Zone Corruption Raid, Deepening Political Tensions
Iraqi security forces arrested several senior political figures in a series of overnight raids inside Baghdad's heavily fortified Green Zone.
Al-Diriyah join race for Soule who remains unconvinced
Matias Soulé’s future seems far from Rome. Regardless of what happens by tomorrow, the Argentine winger is expected to leave the capital, as the Giallorossi have clear ideas about who will play in ...
At Universal Horror Unleashed in Las Vegas, fear is always in season
Your nightmare awaits at the AREA15 year-round attraction.
AB Science reports completion of the step 3 of phase 1, evaluating the combination of AB8939 with venetoclax for the treatment of refractory or relapsed AML
PRESS RELEASE AB SCIENCE REPORTS COMPLETION OF THE STEP 3 OF PHASE 1, EVALUATING THE COMBINATION OF AB8939 WITH VENETOCLAX FOR THE TREATMENT OF REFRACTORY OR RELAPSED ACUTE MYELOID LEUKEMIA THE COMBINATION OF AB8939 WITH VENETOCLAX GENERATED A 67% OVERALL RESPONSE RATE (ORR) AND A 100% DISEASE CONTROL RATE (DCR), WITH NO DOSE-LIMITING TOXICITIES (DLT) OBSERVED, IN A POOR-PROGNOSIS POPULATION WITH ADVERSE GENETICS TREATED IN THE SECOND - TO FOURTH-LINE RELAPSED OR REFRACTORY SETTING Paris, June 2
Cognition's CEO says token leaderboards are 'directionally correct'
Cognition CEO Scott Wu said there are better ways to incentivize employees to use AI.
Reporter talks environmental, health impacts of mining efforts near Boundary Waters
WTIP spoke to Benji Jones, Senior Correspondent at Vox Media, about what environmental and health experts are saying about the proposed Twin Metals mining project in the Boundary Waters Watershed. Jones’ article “Mining these metals could be a boon for the climate — but there’s one big catch,” is currently available at vox.com. Below is...
Iraq detains politicians, officials in anti-corruption crackdown
Iraqi security forces arrested politicians and senior officials early on Sunday as part of a broader anti-corruption campaign ordered by Prime Minister Ali al‑Zaidi, a government spokesperson said.
Spend Five Minutes With This Hellish Operating System Simulator and You'll Never Swear at Your Computer Again
Seriously, I'm sorry I had a gazillion browser tabs open alongside several hours' worth of unsaved work. Please don't crash. Please.
New packaging for Apple's A20 Pro chip should keep the iPhone 18 Pro series feeling cool
With everyone worried about chips and phones heating up, processors are getting improved thermal management tools.
2026 World Cup Betting Report: 'USA Is By Far Our Worst Result In The Book'
There's no way around it: The USA making a deep run at the World Cup would be a horrendous result for sportsbooks. Patrick Everson reports.
Two years after their last debate, Biden jabs at Trump: ‘What a loser’
As he rallied Maryland Democrats at a state party fundraiser Saturday night, former President Joe Biden decried the actions of the man who succeeded him in the White House, painting him as vain and corrupt.
Texas Democrats welcome Bernie Sanders and plunge into economic populism
In speeches and conversations throughout the convention, Texas Democrats embraced affordability and anti-corruption themes championed by the Independent senator from Vermont.
States seek to lower drug prices by targeting the companies that manage them for health plans
TOPEKA, Kan. — As consumers worry about medication costs, states are trying to lower drug prices by reining in big companies that oversee prescription coverage for health insurers. Some of those companies, called pharmacy benefit managers, also own pharmacies, and one of them, CVS, has spent millions of dollars fighting
Isha Johansen on the promise and politics of football
The first female president of the Sierra Leone Football Association discusses her new memoir, corruption in the game, and rebuilding through sport.
Why the CEO of AllianceBernstein says you should worry about an AI bubble
"Is it likely we have a meaningful correction? I think it is," AllianceBernstein's CEO told Business Insider in an interview.
City of Covington awards final round of fiscal year 2026 Small Business Incentive program funding
The City of Covington continues its commitment to supporting entrepreneurs, revitalizing commercial corridors, and strengthening neighborhood business districts through the Covington Small Business Incentive Program. The Covington Board of Commissioners has approved the fourth and final round of Fiscal Year 2026 Small Business Incentive Program funding, awarding $28,000 to support four projects across the city....
Peters, Bergman lead Michigan delegation in calling on Small Business Administration to approve disaster declaration
WASHINGTON, DC — U.S. Senator Gary Peters (D-MI), Ranking Member of the Homeland Security and Governmental Affairs Committee, led members of the Michigan Congressional Delegation in urging the Small Business Administration (SBA) to support Michigan Governor Gretchen Whitmer’s request for an administrative disaster declaration following the severe thunderstorms, tornadoes, high winds, large hail and torrential […]
The impact of club sports on student experience in higher education
Authors: Ryan Savitz1, Divit Gupta2, Jared Ward3, Andrew Bjorkelo1 1Neumann University 2Conestoga High School 3Brigham Young University Corresponding Author: Ryan Savitz savitzr@neumann.edu …
Why JD Vance is downplaying Richard Nixon’s corruption
It’s not every day that you see the would-be frontrunner for a major party’s presidential nomination extolling the virtues of Richard Nixon and downplaying his corruption.
Horry County business evacuated after reported gas leak
A gas leak in Horry County has caused a business to evacuate.
Scientists infected a 'vagina on a chip' with gonorrhea — then cured it with a new antibiotic found by AI
To sift through 6 million molecules in pursuit of new gonorrhea treatments, researchers trained AI to select the best drug candidate and then tested it in a "vagina on a chip."
PENN Entertainment (PENN) Just Overtook the 20-Day Moving Average
Should investors be excited or worried when a stock crosses above the 20-day simple moving average?
New Linux pedit COW Exploit Enables Root Access by Poisoning Cached Binaries
CVE-2026-46331 lets local users gain root on affected Linux systems by corrupting page-cache memory through act_pedit.
Rain stopped play? Biggest worry now in British sport is extreme heat
Climate crisis is on show every day when sportspeople do their thing and the rest of us sweat on the sofa
EVA HENRY: Corruption resurfaces in Adams, Arapahoe County politics linked to One Main Street
Corporate dark money groups are funneling millions into eleven different races statewide.
As San Joaquin County sees rise in rabid bats, public health says not to worry
2026 World Cup Is Putting FIFA’s Rules on Political Neutrality to the Test
The World Cup is in full swing across North America, and the U.S. men’s team faces Turkey in its final group round appearance on Thursday. But behind the cheering fans and nail biting matches, FIFA's commitment to political neutrality is put to the test. Marisa sits down with Tariq Panja, global sports correspondent at The New York Times. They dig into the politics behind the games, from restrictions on Iran’s team and President Trump’s unusually close relationship with FIFA president Giann
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Edgefield County health fair offering free screenings, vendors, and entertainment
JOHNSTON, S.C. (WJBF) — A free community health fair is headed to Edgefield County. “Prevention Today for a Healthier Tomorrow,” set for Friday, June 26 from 10 to 1 at Strom Thurmond High School i…
Falls Church Business News & Notes 6-25-2026 - Falls Church News-Press Online
Falls Church Business News & Notes Falls Church Business News & Notes Local Business Updates A full interactive roundup of chamber recognitions, business expansions, events, regional awards, and one correction. Expand All 8 total notes Includes full correction Links preserved Chamber Businesses Named Top Workplaces New Editions Consulting ranked #2 among small businesses. ⌄ New
Platner, Collins’ campaign spar over federal contracts
Platner released a multi-point plan he calls “a corruption crackdown,” which covers issues such as big money in politics, lobbying activities by former members of Congress, and making it more difficult for presidents to cash in on their position while in office.
Major part of student-loan repayment overhaul is blocked in court
A federal court ruled that the Education Department's proposed borrowing caps for advanced healthcare programs cannot take effect on July 1.
News | Family entertainment company inks retail lease at West Michigan shopping center
Screen-free indoor play operator plans fall move-in at popular Walker retail corridor
How should European scientists respond to the US AI kill switch?
Earlier in June, Europe’s worst fears of technological dependence were confirmed when the White House ordered the AI firm Anthropic to stop non-US citizens using its leading models. This kill-switch moment crystalised anxieties in Brussels that the continent, lagging the US on the creation of leading-edge AI models, is now a technological of vassal of Washington. The shock has specific implications for European scientists and universities. Some governments are now worried that with AI being integrated into labs, Donald Trump now has his finger hovering over an off switch for European science. “Having restrictions on this tool, it can have an impact on our own research,” said France’s research minister, Philippe Baptiste, at the VivaTech conference in Paris on June 18.Baptiste, himself a former academic, said that colleagues in mathematics had recently warned him they were now cut off from leading-edge US models, risking their work. “This model is not available anymore now because of the US restriction, and for the first time this had an impact on mathematics,” a field where large language models (LLMs) are making a significant contribution, said Baptiste. So, should European scientists avoid relying on US models in the future? Or would this be a self-harming overreaction? And how is AI being used in science, anyway? What happened?On June 12, it emerged that Washington, citing cybersecurity concerns, had ordered Anthropic to stop non-US citizens using two models: Claude Mythos 5, and Claude Fable 5, a version of Mythos but with guardrails to prevent abuse. Anthropic said Washington’s concerns were overblown. But forced to follow the order, yet with no way to check who was using the models, the company suddenly shut down access for everyone, US citizens included. There’s still no agreement on how to restore broad access. But last week, Bloomberg reported that select US companies, and the US government, still had access to Mythos despite the ban, but the EU’s cybersecurity agency Enisa had been shut out. Class division of researchersIn the longer term, access outside the US should be restored, said Marcel Salathé, co-director of the AI centre at the Federal Polytechnic School of Lausanne (EPFL), because a permanent restriction would be financially ruinous to US AI firms. “Even Trump will eventually budge to economic pressure,” he said.However, US AI firms might end up operating rather like banks, doing due diligence on users of their leading-edge AI models, he went on.European scientists are unlikely to fall foul of such checks, he said. But having a Chinese postgraduate in their lab, or doing a type of research the US disapproved of, could potentially result in access being denied. “It will create a sort of class division of researchers,” he said. More than frontier modelsHowever, successfully deploying AI in science is about far more than just having access to leading LLMs such as Mythos.Instead, many science-specific tools, most famously Alphafold, which predicts protein folding structures, require “far less” computing power to train than frontier models, well within the capabilities of European supercomputers, according to a recent analysis by the Arq Foundation, a Brussel-based AI think tank. Instead, tools such as Alphafold are possible because certain fields, like protein folding, weather prediction or astronomy, have large, clean, standardised datasets that can be used to train predictive models. Rather than compute, “data is the central constraint for AI for science,” the report says. For example, a less powerful physics model trained on CERN’s data “will be more valuable than the best model without certain data,” said Bengüsu Özcan, author of the report. European advantage?Europe could therefore steal a march by using its scientific data and infrastructure to create models US digital giants cannot. “They might actually match or go even beyond what these big [US] companies are doing,” said Özcan.Indeed, some European start-ups hope to create automated testing labs to create the kind of standardised data that could speed up the discovery of new materials. Materials scientists say there’s currently too little data to train models. AI scientistsHowever, even if the bottleneck for AI in science is often data, rather than compute, being at the mercy of the US for LLM access could still become a problem for European scientists. A new class of “AI scientists” based on leading LLMs is also emerging, Özcan’s report says.Unlike domain-specific tools like Alphafold, these try to automate day-to-day scientific work, by providing an overarching tool that coordinates specific models to synthesise existing literature, generate hypotheses or run analysis of data. The problem for Europe, however, is that these tools are sometimes based on US leading models. Google Deepmind’s AI Co-Scientist, for example, is built on Google’s Gemini LLM. Systematic failureThese scientific automation tools are still in their early stages, and still exhibit “systematic failures on scientific tasks,” Özcan’s report says. One of the problems is that the messy, day-to-day process of scientific discovery is largely not documented, meaning LLMs don’t have a good source of data to learn how scientists actually work. Meanwhile, some tasks, such as literature synthesis, don’t typically require access to leading edge models.However, the performance of AI scientific assistants could improve as companies such as Google pour resources into developing them. Rely on US“Unfortunately, for scientific assistants, there is not much we can do right now except rely on US frontier AI,” said Antoine Bosselut, a natural language processing expert based at EPFL. Chinese-built open models, which can run on local computers, lessening the risk of a shutdown, are touted as one alternative to US dependence. There’s also Mistral, once seen as Europe’s main AI hope, but the Paris-based company has seen its recent models fall behind in performance. But the Chinese alternatives are generally not as capable as US frontier AI models, said Bosselut, unless paired with fiddly, custom tools that allows them to act as independent agents. “Most scientists do not have the time,” he said. Don’t jump ship yetAlthough the kill switch moment is seen a warning shot for European scientists, it doesn’t mean labs should abandon US AI tools immediately. “I do not think the right response is simply to abandon US-based models and systems under the banner of sovereignty or independence,” said Mattias Björnmalm, secretary general of the Cesaer university association. “That would be an overreaction.”Related articlesEuropean sovereignty in AI requires ‘ugly trade-offs,’ say experts Robotic lab start-up makes case for €500M EU-funded materials testing facilityAI in science: is it useful? Instead, European researchers need to ask themselves whether they’re becoming dependent on technology that could be turned off in Washington, said Özcan. “They might not see this today, but they should really start asking this question,” she said. European researchers need a plan B, said Salathé. “I would recommend to every researcher, very proactively explore alternatives.”Own toolsIn addition, Björnmalm and others want European research institutions to develop their own scientific AI tools.Instead of signing AI deals with US digital giants, European universities should be using this money to create their own models, which may end up being superior for research, said Sabine Leonelli, an expert on the use of AI in science at the Technical University of Munich. “Universities in Europe seem to be happy to sign commercial contracts with US companies on the assumption [their AI tools] are better,” she said. But US frontier LLMs are typically opaque, and have been developed without independent scientific input, she said. “This is not good enough for science.”Last year, Swiss researchers released Apertus, an LLM designed to be completely transparent, from its development methods to its training data. The idea is that this makes scientific tools built on top of the model far more reproducible than with closed, commercial alternatives.“Europe needs more of this: serious capacity-building that gives researchers, universities and companies credible options,” said Björnmalm.
Ford Road growth continues in Canton. Here's 9 projects to know about
New restaurants and retail projects are reshaping the busy Ford Road corridor in Canton. See what's coming next.
Who's No. 1 in Morris/Sussex high school sports?
The Daily Record and New Jersey Herald totaled up each high school's 2025-26 success to determine the Top 10 athletic programs.
After Jordan Kyrou trade, Blues are open for business — and positioned for a franchise-changing run
With four firsts after move, GM Doug Armstrong is preparing for a transaction marathon — "a 6-mile jog tomorrow and an 8-mile run Friday."
GTA VI is a worrying sign for the future of physical games
Your GTA VI box will have a download code, but not a disc.
Gas prices, health, quality of life drive push for more Coloradans to trade four wheels for two, even if safety is a worry
Bike to Work Day brings out the cyclists in Denver, but many already pedal to their jobs and back.
This health data provider could benefit as AI reshapes drug research
Harvey Stober, senior equity analyst and correspondent at CNBC, explains why this healthcare company could benefit from artificial intelligence reshaping the drug industry thanks to its treasure trove of data.
Hollister’s First-Ever Target Collection Reveals a 3-Step Growth Strategy Any Business Can Copy
Hollister's first home collection is a move from closet share to lifestyle share, and a growth playbook any founder can borrow.
NFL offseason power rankings: No. 31 New York Jets try to put Aaron Glenn's horrific first season behind them
Governor Morrisey Announces $2.4 Million Investment to Expand Worksite Clinics Across West Virginia
CHARLESTON, W.Va. - Governor Patrick Morrisey today announced a $2.4 million investment to expand access to worksite-based healthcare services across West Virginia. Through the state's Rural Health Transformation Program (RHTP), the funding will expand employer-based health services and strengthen workforce participation as part of the Health to Prosperity (HTP) initiative. With this announcement, total funding opportunities and implementation initiatives under RHTP now exceed $88.5 million.
This week in Santa Cruz County business: Capitola Wharf business faces uncertain future; Aptos Village business owners and RTC head to court
A proposed new policy regarding leases of city-owned property has the owner of Capitola Boat & Bait worried her business could be priced off the wharf, Jessica M. Pasko reports in her weekly column.
German Business Outlook Improves Slightly as Uncertainty Wanes
Germany’s business outlook brightened slightly in June, easing worries about the knock-on effects of the Iran war on Europe’s largest economy.
Younger Adults May Be Aging Faster Than Previous Generations
This could explain a worrying trend.
See the Colts' career passing leaders
See the top 10 Colts in passing yards from Peyton Manning to Earl Morrall
Jeremy Clarkson's health dilemma 'common among farmers'
The TV star shared his worried treatment would overlap with a busy period for his Cotswolds farm.
A federal judge orders an ICE detainee with mental illness released, finding her six-month detention unconstitutional
The ruling followed a hearing that exposed a sharp divide over how a Vermont prison's mental health providers, a corrections officer and outside clinicians assessed the woman’s mental illness, a dispute the judge did not resolve.
FedEx posts strong earnings results in last quarter with freight business
FedEx posted strong fiscal fourth quarter earnings on Tuesday in the company's last quarter that included the freight business before its spin-off.
Roku May Help Fox Avoid Aggregeddon
(Welcome to the “Most Important Story of the Week”, my bi-weekly strategy column analyzing the most important (but often not buzziest) news story of the last two weeks. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. Please subscribe.) Scrolling through links over the last week, I stumbled across this fun headline: Wow. Formula 1 (the sport, not the docu-series) is the perfect “dog not barking”. As a reminder, each week in my Streaming Ratings Report, I call out the shows that miss every viewership chart. I dub them “dogs not barking”—like the Sherlock Holmes mystery—because without any data, we forget they even exist. This is in contrast to something like, say, a film flop—cough The Mandalorian and Grogu cough—where even underperforming at the box office is widely discussed here, there and everywhere. In the US, Formula 1 is now in “no public viewership data, so not discussed” territory. After moving to Apple TV from its former home of ESPN, basically no one talks about it. Apple did publish an initial, unsourced, unsubstantiated, (dare I say unserious) datecdote claiming more folks are watching Formula 1 on Apple than ESPN, but we haven’t gotten any updates since. This stands in contrast to when the sport streamed on ESPN, and ESPN PR provided weekly viewership figures. Formula 1 was, at best, a niche sport in America—averaging 1.3 million viewers in the Big Data Plus era—but now it’s basically anonymous. (And yeah, after moving to Apple, I very, very, very much doubt its ratings increased.) Unfortunately, that story isn’t quite big enough to warrant a section in today’s “Most Important Story of the Week” column, but I wanted to call it out, because otherwise, no one else will! Certainly, no one will write articles about the silence/ratings decline, unlike when they wrote breathless articles connecting the rise in viewership to Netflix’s Drive to Survive, including Reuters just last month. (This is a topic I’ve tried to provide a moderate/nuanced/non-hyped take since 2022.) Anyway, on to this week’s issue. I was a bit worried I didn’t have a juicy topic, then the Murdochs went out and did their Murdoch thing: buying Roku. So that’s the story of the week, and it happens to touch on quite a few themes of the streaming wars and the disruption therein. I’ll cover that, plus why more consolidation in Hollywood media looks likely, more good news on the Hollywood labor front, whether we’ll see an uptick in production in Los Angeles, some Broadway and theme park news, cellphone prices going up in the third world (and possibly everywhere), and more. Subscribe Most Important Story of the Week - Another Big Media & Entertainment Merger The story of the week is clearly Fox is buying Roku for $22 billion. I read a lot of good strategy takes on why Fox bought this streaming TV device maker—and I’ll have mine below—but what fascinates me more is how this deal connects to quite a few themes of the streaming wars, linking to everything from the pace of M&A to “aggregeddon” to Netflix’s recent M&A actions/inactions to the shift to advertising from pure play streaming and more. The only topic I can’t really connect it to is my old theory, “never bet against Rupert Murdoch” because he isn’t the one who did this deal; his son Lachlan inked it. (Do I think he provided advice, even at his 95 years of age? Sure.) That plus I have one additional piece of strategy for all entertainment players, inspired by this deal. So let’s dive into all those topics, starting with why I like this deal. Roku is a Great M&A Buy
Why Paranoia About AI Is Healthy For Business Owners (and Panic Isn’t)
If you’re a business owner worried about AI, here’s what I’d tell you: Be paranoid, but not panicked. Look directly at AI, and learn to use it.
RWJBarnabas Health and Rutgers Cancer Institute Unveil the Melchiorre Cancer Center, Expanding Access to World-Class Cancer Care
Today, RWJBarnabas Health and Rutgers Cancer Institute, the state’s only National Cancer Institute-designated Comprehensive Cancer Center, unveiled the Melchiorre Cancer Center at Cooperman Barnabas Medical Center.
'Voicemails for Isabelle' director was worried end cameo scene would come off 'creepy' (exclusive)
Netflix's new hit rom-com, 'Voicemails for Isabelle,' includes a poignant appearance in the film's final moments. Writer-director Leah McKendrick talks to EW about her decision to include that cameo, and her fear that it would feel 'creepy.'
Chicago’s Bike Lanes Don’t Hurt Businesses, City Report Finds
As protected bike lanes face opposition in some neighborhoods, city-backed case studies found lanes in a half-dozen corridors have not contributed to a negative impact on economic activity.
Student Turns LEGO Resale Hobby Into $50,000 Business
Cedarville University senior Micah Torres turned a LEGO minifigure hobby into Rusty’s Figs, a business generating $50,000 in revenue. Through mentorship, faith and...
'House of the Dragon' Season 3, episode 1: Aegon originally knelt. Tom Glynn-Carney changed it.
Inside Larys and Aegon's terrible, horrible, no good, very bad road trip.
Louisiana Sports Hall of Fame Preview: Warren Morris
LSU Legend Warren Morris will receive the Ambassador Award from the Louisiana Sports Hall of Fame this weekend.
Gov. Scott vetoed the Legislature’s latest attempt to lower health insurance costs. What’s next?
Scott wants to expand other models of health insurance in Vermont. Observers worry that his veto points to deepening political divisions over how to keep healthcare affordable.
Santana: Politician Spending Accounts Fuel Banana Republic Politics Across OC
Despite recent grand jury warnings, OC Supervisors tomorrow are ready to vote to keep spending and creating multi-million dollar, taxpayer-funded discretionary spending accounts.
Hideo Kojima Shares New Screenshot Of Upcoming Horror Game OD And...Hey, That Looks Like PT!
Playable Teaser? More like....uh...Passageway...Terrifying!
Hungary’s PM launches drive to free country from Orban’s ‘mafia’
The raft of proposed changes includes a new constitution and anti-corruption office, and the ousting of the president.
Kojima Says Only Xbox And Phil Spencer Understood OD, His New Horror Game
Apparently, former Xbox boss Phil Spencer got OD while other video game CEOs didn't
Kojima Says OD Will Push Horror’s Limits, as Todd Howard Gives TES VI Update and Praises Arkane’s Blade
Kojima says OD will push horror’s limits, while Todd Howard gives a The Elder Scrolls VI update and says Arkane is doing great on Blade.
Hideo Kojima Says Upcoming Xbox Horror Game OD Has a Special System for People Who Are Too Scared to Keep Playing
Hideo Kojima has teased his upcoming Xbox horror game, OD, revealing it includes a special system designed for people who are too scared to keep playing.
Fans Recoil At ‘GTA 6’ Price Leak, Which Turns Out To Be False, For Now
GTA 6 is about to be up for preorder, but a leak had fans worried it's going to be very expensive. That, however, seems to be false. At least for now.
Massive fire erupts in Montgomery County warehouse
Firefighters are battling a major blaze at a warehouse in Montgomery County.
Business Insider wins Capital Emmy
The project was reported and produced by Business Insider's Chief Video Correspondent Graham Flanagan as part of the Boot Camp franchise.
Every Apple Watch Model Hits Its Lowest Price Ever for Prime Day
Prime Day deals are already in full swing today, despite the event not kicking off until tomorrow, June 23. Below we're tracking all-time low prices across the Apple Watch lineup, including Apple Watch Series 11 for $120 off, Apple Watch SE 3 for $50 off, and Apple Watch Ultra 3 for $150 off. Note: MacRumors is an affiliate partner with Amazon. When you click a link and make a purchase, we may receive a small payment, which helps us keep the site running.
Experiencing the newly-opened Guy Fieri dining and entertaining concept, Downtown Flavortown
Celebrity chef Guy Fieri opens new restaurant, Downtown Flavortown, in Myrtle Beach.
The Jacob Engels attacks don't worry me. This does
I never thought he warranted the attention.
Politician behind 'top two' primary has second thoughts
The man who brought California the top-two open primary now thinks it needs a drastic overhaul.