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Monrovia business owners say sudden closure of beloved movie theater could have negative ripple effect
Standout safety reclassifies to 2027, recruitment picking up
One of the top safeties in the 2028 class has opted to reclassify to the 2027 class with his recruitment picking up steam.
Trump’s New Political Tool: ICE
President Trump has increasingly used Immigration and Customs Enforcement to push personal and political objectives, and on Monday sent agents to airports across the country to help deal with long security lines.
Mullin’s Smooth Confirmation Was a Throwback in the Senate
In choosing Senator Markwayne Mullin, who has warm relationships across the Capitol and the political aisle, President Trump was reverting to a bygone tradition.
Struggling LA businesses face more concerns because of surging gas prices
Freddie Freeman might hit 5th against some left-handed pitchers
Whether it’s the Teoscar Tax or the Smith Levy, Freeman hasn’t batted lower than 4th since 2016
Entertainment and more in the Mid-Ohio Valley
PARKERSBURG – The Artsbridge calendar for this week: TODAY * Geppetto Woodcarver’s Wood Quilt display, 9 a.m. to 4 p.m., WesBanco, Market Street, Parkersburg * Art is Life/Life is Art, ages 55-plus,10:30 a.m. to 12:30 p.m., Parkersburg Art Center * Butterfly Photo Holder, ages 13-plus,11 a.m. to noon, Marietta Public Library * Hygge Club, adults, […]
Trump Delays Threat to Iran, but War Negotiations Are in Early Stage
President Trump postponed his threat to strike power plants in Iran, citing “productive conversations” with the Iranians. But officials said the talks were in an early stage and not substantive.
Detroit Tigers' Opening Day be on cable TV? Here's what we know
The Detroit Tigers haven't been able to give details on their broadcast service, Detroit SportsNet, and its status on cable TV packages.
Businesses prepare for Treefort Music Fest to take over downtown Boise
The Monday Outlook: Project Hail Mary and the Science Behind Blockbuster Sci-Fi
Project Hail Mary is the latest sci-fi blockbuster to stretch the bounds of audience imagination and stir the curiosity of real scientists. But the science driving films like Project Hail Mary, Interstellar and The Martian isn’t all fictional: at UChicago, researchers exploring the cosmos and decoding the origins of life are making discoveries that would feel right at home on the big screen. This week's Monday Outlook features scientists from UChicago and Argonne National Laborat
SC sees historical ranking in a 2025 national health ranking
South Carolina came in at 36th in the United Health Foundation's America Health Rankings 2025 annual report, the state’s best ranking since the report started b
‘Don’t Make Any Deal’: Trump Tells Republicans to Hold Firm on Shutdown Talks
The president is using the standoff over funding the Department of Homeland Security as leverage to pass a strict voter ID bill. Critics say the bill would place an undue burden on eligible voters.
UFL 2026: Joel Klatt, Curt Menefee Return To Headline FOX Broadcast Team
Joel Klatt and Curt Menefee will once again lead FOX Sports' broadcast coverage for the highly anticipated third season of the UFL.
White House pitches pharma on pricing draft
Plus: Names of the candidates to lead the CDC
'Sled head': Lawsuits against USA Bobsled/Skeleton allege brain injury
Three personal injury lawsuits have been filed on behalf of elite bobsledders who claim officials intentionally concealed evidence that the sport causes brain injuries.
Cincinnati hires Jerrod Calhoun: Utah State coach leaving after two years to guide his alma mater
The Bearcats have agreed to a six-year deal with the 44-year-old coach, a source told CBS Sports
2026 NCAA Tournament second round schedule: March Madness bracket, game dates, tip times, TV channels
Check out the master schedule for the first and second rounds of the 2026 NCAA Tournament so you can watch all the March Madness
Trump administration adds State Health Officer Dr. Daniel Edney to short list of nominees for CDC director
State Health Officer Dr. Dan Edney is among the contenders to head the nation’s Centers for Disease Control and Prevention, the Washington Post reported
AI attack ads are hitting Massachusetts political campaigns
Lawmakers are considering new legislation to regulate the use of AI in political advertising. Have you spotted them?
Several vehicles catch fire at used auto parts business on West Beaver Street
The Jacksonville Fire and Rescue Department has confirmed that several vehicles are on fire at a business on West Beaver Street.
Apple sets June date for WWDC 2026, teasing "AI advancements"
Apple will host its next Worldwide Developers Conference the week of June 8. The company is expected to announce major updates to Siri with advanced AI capabilities.
Apple to Start AI Comeback Bid on June 8 With Annual WWDC Conference
Apple Inc. announced plans to hold its annual Worldwide Developers Conference from June 8 to June 12, when the company is poised to unveil a make-or-break collection of AI features.
Californians may need to mail ballots early as Supreme Court signals support for new election day deadline
California counts mail-in ballots that arrive up to seven days after election day, but that option may be deemed illegal
Seattle Sports This Week: TV and radio for March 23-29
A look at the broadcast schedule for March 16-22 on Seattle Sports 710 AM and the Seattle Sports app, as well as local sports teams on TV.
Voice of America Journalists Sue, Saying Trump Officials Interfered in Coverage
The journalists said in the complaint that the administration was trying to force them to be a “mouthpiece” and that one official demanded “loyalty” if reporters wanted to “keep their jobs.”
Ewing to announce entertainment for Omaha’s Memorial Park concert
The event is happening on Friday, June 26.
Ewing to announce entertainment for Omaha’s Memorial Park concert
The event is happening on Friday, June 26.
Pop superstar announces summer concert tour, including stop in central Pa.
"The Freedom Tour" will make a stop in Hershey this August.
2nd Car Show Scheduled at Sangertown Square
Racing fans and families can check out high-performance cars and meet local drivers at the Mall Car Show at Sangertown Square.
Crab Nebula Expansion over 25 Years
These two Hubble images compare the Crab Nebula in 1999 to 2024, revealing its expansion over the years.
Health in a Handbasket: Chips & Dip
Today we're putting a healthy spin on a snack we all know and love.
Cowboys mock draft tracker: A trade might make sense early
How interested are you in trading back in the first round?
Cycling, crystals and cutting-edge science: the secrets of Hodgkinson and Hunter Bell’s success
The training duo who oversaw famous medal success in Torun believe the best is yet to come for their athletes
Trump to Maria Bartiromo: Iran wants to make a deal badly, could be within 5 days or sooner
Maria Bartiromo reports that President Donald Trump says Iran ‘wants to make a deal badly’ as he orders a five-day pause on planned strikes against key infrastructure, signaling ongoing high-level talks and triggering a sharp market rebound.
Blue Jays extend manager John Schneider, GM Ross Atkins following World Series appearance
The Blue Jays are locking up two architects of the team's World Series run.
Emmanuel Grégoire, Socialist long involved in local politics, voted new Paris mayor; AP explains
Grégoire won over 50% of the votes, beating out prominent conservative contender Rachida Dati who reached 41% while hard-left contender Sophia Chikirou got about 8%.
Inaugural Health Care by Food research award honors excellence in food is medicine science
DALLAS, March 23, 2026 — At a time when American dietary patterns are facing renewed attention, the American Heart Association has announced its inaugural Health Care by Food™ Most Impactful Food Is Medicine Research Award, honoring the year’s most...
Inaugural Health Care by Food research award honors excellence in food is medicine science
DALLAS, March 23, 2026 — At a time when American dietary patterns are facing renewed attention, the American Heart Association has announced its inaugural Health Care by Food™ Most Impactful Food Is Medicine Research Award, honoring the year’s most...
“It’s a bit of an event. It’s not a sport” - Kevin Garnett thinks the modern NBA is more entertainment than competition
Kevin Garnett says NBA has become entertainment-driven.
Spurs vs. Heat odds, prediction, time: 2026 NBA picks for Monday, March 23 from proven model
SportsLine's proven model has revealed its San Antonio Spurs vs. Miami Heat predictions and NBA picks today
'A towering figure in French politics': reactions to Lionel Jospin's death pour in
Lionel Jospin, Socialist prime minister of France from 1997 to 2002, has died.
Berrien County Health Department will hold free hearing, vision screenings for kids
The Berrien County Health Department will offer free hearing and vision screenings for kids throughout spring break.Clinics will be held March 30 at the departm
Inside the Turmoil at RFK Jr.’s CDC, as Told by Current and Former Employees
Forty-three current and former C.D.C. employees on the changes they say are replacing science with ideology — and making Americans more vulnerable.
Tribune All-Area girls' basketball team full of winners
2025-26 Tribune All-Area girls' basketball team features a group of winners, boasting a ton of talent on the hardwood.
AI Swarm Attacks Are Coming, Is Your Business Ready?
Leaders need a new cybersecurity playbook for the agentic era, with stronger governance, faster response systems, workforce awareness, and up-to-date security frameworks.
Turning coal to medicines: Chinese scientists bring a 160-year-old dream to life
Study cracks a puzzle that has baffled scientists and will reshape modern medicine production as the world reels from a global oil shortage.
Breaking the Cycle review – meet the charismatic Thai politician striving to change his country’s history
Gripping documentary examines the Future Forward Party’s unprecedented 2019 election result, and its leader’s aim to break Thailand’s repeated military coups
Devin Booker gets 100% on Suns’ playoff seeding chase
Devin Booker knows where the Suns sit amid their previous five-game skid and how it impacts the playoff seeding chase.
Funding for populist-right ‘media-political complex’ exceeded £170m in five years, research finds
Handful of billionaires gave huge sums in particular to media organisations that boosted rightwing politicians, says Liam Byrne MP
St. Louis Blues Weekly Prospect Report (March 22)
Jiricek has big scoring week; McIsaac announces future plans; Ralph, Michigan State head to NCAA Tournament with Mayich, Clarkson University eliminated; Peterson scored pair, including a SH beauty for Springfield
Cleanup underway after pick-up truck crashed into science surplus store in Geneva
Thru The Game is changing the game for athletes' mental health in Colorado
How Obama’s Strategist Discouraged Biden From Running in 2016
In a new set of oral histories, David Plouffe, President Barack Obama’s political adviser, described how he urged Vice President Joseph R. Biden Jr. not to challenge Hillary Clinton for the nomination.
Norman City Council to consider ordinance repeal related to Rock Creek Entertainment District
Norman City Council will consider repealing an ordinance related to the Rock Creek Entertainment District during its Tuesday meeting, according to a council member’s social media post.
Students Learn the Science of Tree Felling at Treehaven
Click here to view this video from wjfw.com.
'Harry Potter' star details racist 'abuse' he suffered after joining upcoming TV show
Paapa Essiedu is speaking out about on 'abuse' he's endured since being cast as Severus Snape in the 'Harry Potter' TV series: 'Nobody should have to encounter this for doing their job.'
UTA College of Business to connect students, professionals with networking, elevator pitch event
Students, business professionals and recruiters will mingle from 6 to 8 p.m. Monday at the UTA Center for Entrepreneurship and Technology Development.
One dead after shooting at Last Call Sports Bar in Jackson
One person is dead after a shooting at Last Call Sports Bar early Sunday morning.
Precision Nutrition: Tufts University Expert Q&A On How Personalized Diet Science May Transform Health - Where The Food Comes From
Tufts expert José Ordovás explains precision nutrition and how personalized diet science could transform health and prevent disease.
Kansas squanders its best player as Darryn Peterson's college career with second-round loss to St. John's
The Peterson era in Lawrence is likely over.
Apple’s Worldwide Developers Conference returns the week of June 8
Apple today announced it will host its annual Worldwide Developers Conference (WWDC) online from June 8-12.
Carrie Anne Fleming, 'Supernatural' and 'iZombie' actress, dies at 51
Carrie Anne Fleming, who appeared on 3 episodes of 'Supernatural' as Bobby's wife Karen, has died. She was 51.
'Project Hail Mary' blasts off to record-breaking $80 million, becomes 2026's best premiere
'Project Hail Mary' burned through the outer layer of box office projections this weekend, reaching an astounding $80 million in its domestic premiere and $141 million worldwide.
Students compete in Virginia Science Olympiad State Tournament at UVA
The tournament’s events ranged from knowledge tests to building robots.
Students compete in Virginia Science Olympiad State Tournament at UVA
The tournament’s events ranged from knowledge tests to building robots.
Sunday Sports: Sackets hoops in the state finals, plus updates on SU sports
Here’s a recap of your North Country sports this Sunday.
The Cowboys are making a mistake with this move
The Cowboys still have to find help at linebacker.
Israel Thought It Could Spur Rebellion Inside Iran. That Hasn’t Happened.
President Trump’s hopes that an Israeli plan to ignite an internal uprising against Iran’s theocratic government could bring the war to a swift end have so far been dashed.
Khloé Kardashian Recalls How Her Divorce from Lamar Odom Made Her ‘Obsessed’ with Leading a Healthy Lifestyle
Khloé Kardashian opened up about her relationship with diet and exercise on the March 18 episode of her podcast, ‘Khloé in Wonder Land.’ She said she became ‘obsessed’ with exercise after examining how her food choices were affecting her quality of life.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Mississippi State Health Officer Dr. Daniel Edney, a Vaccine Proponent, Is Under Consideration to Lead the CDC
Dr. Daniel P. Edney, Mississippi’s state health officer and head of the Mississippi State Department of Health, is now under serious consideration to lead the CDC.
Kennedy’s latest MAHA-approved plan could supercharge peptide boom
He indicated that the FDA will soon widen access to the small proteins, which biohackers tout as therapies for a range of ills
Chiefs’ 2026 NFL Mock Draft roundup after NFL Free Agency
A closer look at the Chiefs’ 2026 mock draft outlook after free agency, with linked to edge help, cornerback, and offensive line support.
Wake County childcare centers take preventive measures as measles cases rise
Phillies sign pitcher Cristopher Sánchez to 6-year, $107 million contract extension
3 restaurants open in Pittsburgh’s East Carson business district
Pittsburgh city leaders celebrated the opening of three new restaurants in the city’s East Carson business district on Friday.
Assemblywoman Alexandra Macedo says César Chávez allegations are "just the tip of the iceberg"
California lawmakers this upcoming week are set to move quickly to rename César Chávez Day to Farmworkers Day ahead of the holiday that takes place every year on March 31.
American football takes for ever. In which other sports do you spend most of your time not playing the game?
The long-running series in which readers answer other readers’ questions on subjects ranging from trivial flights of fancy to profound scientific and philosophical concepts
It’s time to take politics out of the Small Business Administration
The White House’s politicization of the agency will have a real-world impact on small business owners in the US
It’s time to take politics out of the Small Business Administration
The White House’s politicization of the agency will have a real-world impact on small business owners in the US
It's not just vaccines — parents are refusing other routine preventive care for newborns
Doctors are alarmed that skepticism fueled by rising anti-science sentiment is increasingly reaching beyond vaccines to other proven, routine, preventive care for babies.
Apple Has Released More Than 10 Products and Accessories This Month
It has been a busy March for Apple, which has unveiled more than 10 products and accessories this month. However, aside from the all-new MacBook Neo and Studio Display XDR, the devices received faster chips or new colors and little else.
'Everybody Loses' author discusses the meteoric rise of sports gambling
Two years ago, Americans bet $120 billion on sports, a 27% increase from the previous year. That figure grew to $150 billion in 2024. Journalist Danny Funt investigates what's considered one of the most consequential — and least scrutinized — shifts in modern American sports in his new book, "Everybody Loses: The Tumultuous Rise of American Sports Gambling."
NFL Network: What's next for Bills QB Josh Allen? (video)
NFL Network roundtable looks ahead to Josh Allen and the Bills in 2026.
How my time at Goldman is giving me a leg up building a cake business
Allison Sheehan left Goldman Sachs to build her "cake empire," but said her time on Wall Street has taught her crucial skills.
The Best Subscription-Free Home Security Cameras I've Tried
You don’t have to upload your video to the cloud or pay a monthly fee to secure your home. These security cameras record locally.
Southland girls' basketball final rankings for 2025-26 seaosn
A look at the top 20 high school girls' basketball teams in the Southland, led by Open Division state champion Ontario Christian.
White House navigates vaccine politics, midterm risks in CDC director search
The Trump administration faces complicated political dynamics as it seeks someone to helm the key public health agency suffering a prolonged leadership vacuum.
Game Preview: Carolina Hurricanes @ Pittsburgh Penguins 3/22/2026
Who: Carolina Hurricanes (44-19-6, 94 points, 1st place Metropolitan Division) @ Pittsburgh Penguins (35-18-16, 86 points, 2nd place Metropolitan Division) When: 3:00 p.m. eastern How to Watch: Locally broadcast on Sportsnet Pittsburgh and FDSN South, streaming on ESPN+ Pens’ Path Ahead: Quality opponents await in the next week; the Pens host Colorado on Tuesday, an Avs team […]
White House navigates vaccine politics, midterm risks in CDC director search
The Trump administration faces complicated political dynamics as it seeks someone to helm the key public health agency suffering a prolonged leadership vacuum.
New law firm formed; new executive director at chamber; hospital picks new chief of staff
Take a look at some of the recent promotions and new hires announced at south Louisiana businesses.
EA-US Politics Podcast: Mr Trump Goes to War
50-minute analysis of the chaos and destruction of Donald Trump and his inner circle as self-declared "President of Peace" wages war on Iran
Can Manchester City's Guehi play in EFL Cup final?
Manchester City will be without a key defender for Sunday's final at Wembley against Arsenal.
Europe’s trade with Iran: Which countries do the most business with Tehran?
EU–Iran trade fell to its lowest level in two decades in 2025 due to sanctions. Trade continues on a limited scale, with Germany accounting for the largest share.View on euronews
Arizona softball walks off ASU to even series
Arizona softball earned a walk-off win over ASU Saturday night, though not the kind the Wildcats may have been expecting through the first part of the game. Arizona jumped out to an 8-0 lead, then allowed the Sun Devils to claw all the way back before Regan Shockey delivered a walk-off single in the seventh […]
Black Family Wellness Expo brings people together for day of health education
The Black Family Wellness Expo returned to Roselawn Saturday.
Lakers player grades: Luke Kennard gives L.A. ninth straight win
The Lakers defeated the Magic for their ninth straight win thanks to Luke Kennard's heroics at the end of the game.