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Vibe coding could mark the end of the App Store review process as we know it
Toward the tail end of last year, agentic coding (otherwise known as vibe coding) truly took off. With the launch...
To Keep Climate Science Alive, U.S. Researchers Are Speaking in Code
Words considered "woke" are vanishing from research proposals. Grist tracked the changes.
Developers warn flood of vibe-coded apps could slow Apple approvals
AI and "vibe coding" are fueling a boom in new apps, which developers say could lead to delays in Apple's App Store approvals.
Scientists just found a way to store massive data using light in 3 dimensions
A new holographic storage technique uses light in three dimensions to dramatically increase how much data can be stored. It encodes information throughout a material using amplitude, phase, and polarization, rather than just on a surface. An AI model then reconstructs the data from light patterns, simplifying the process. This could pave the way for faster, denser, and more efficient data storage systems.
World's smallest QR code, smaller than bacteria, could store data for centuries
Scientists have created a microscopic QR code so tiny it can only be seen with an electron microscope—smaller than most bacteria and now officially a world record. But this isn’t just about size; it’s about durability. By engraving data into ultra-stable ceramic materials, the team has opened the door to storing information that could last for centuries or even millennia without needing power or maintenance.
Swift, a coding language developed by Apple, now offers official Android support
Roughly a year after the effort was announced, the Apple-developed coding language, Swift, has just launched support for Android. With...
'Hannah Montana' Star Cody Linley Says It's 'Hard to Believe' People Had Shirtless Photos of Him in Their Lockers
Cody Linley reflected on his time as Jake Ryan on 'Hannah Montana' and being a teenage heartthrob, telling Yahoo Entertainment that 'it’s hard to believe that there were girls that had pictures of me with my shirt off in their locker.'
This 1min.AI Advanced Business subscription is just $85
Don’t miss your chance to get an Advanced Business subscription to 1min.AI for just $85 (Reg. $540). Just use the code MARCH15 to get 84% off until March 29
Gambling is entertainment — taxpayers shouldn’t foot the bill for losses.
The tax code should make clear that activities fused with fun, excitement and personal enjoyment are never an occasion for a tax deduction.
Cape Cod’s Best Community’s Choice Awards business spotlight: Carl F. Riedell & Son, Inc.
Nominations for Cape Cod's Best Community's Choice Awards are rolling in! Don't miss your chance to recognize your favorite local businesses.
See 98-year-old 'Taylor Swift of cabaret singers' in Provincetown this summer
The 2026 Provincetown Town Hall series has actors from NBC, HBO shows, Broadway stars, Tony and Grammy nominees, and Ru Paul's Drag Race contestants.
Power Hours: A day in the life of Orangetheory president Lauren Cody
Orangetheory president Lauren Cody said she loves plane rides, green tea, and history. Her routine prioritizes protein and energizing supplements.
Quincy amends code for live entertainment licenses
The City of Quincy is amending city code regarding licenses for live entertainment.
7+ Florida Politics Now: 2026 legislative session and the upcoming special sessions
Cody Butler talks with political analyst Susan MacManus about the 2026 legislative session and the upcoming special sessions.
Who owns college sports? The American people do, and Congress must protect it
Cody Campbell, Founder of Saving College Sports, writes college sports are a public trust, not privately owned by schools or conferences.
Pokémon GO Datamine Reveals Explorer Gadget, a Virtual Auto-Catching Item
Trainers, a new in-game item that could fundamentally change we Trainers play Pokémon GO has been spotted in the game’s code. According to a recent datamine by the ever-watching PokeMiners, Scopely is working on an item called the Explorer Gadget, which appears to replicate the functionality of physical auto-catching devices like the GO Plus and […]
Understanding protein motion could greatly aid new drug design
For many of us, “protein” is the key element of a food order. However, beyond your preferred choice of meats or plant-based alternatives, proteins encompass a large class of complex biomolecules whose chemical structure is encoded in our genes. Proteins have critical functions in living cells: They help repair and build body tissues, drive metabolic reactions, maintain pH and fluid balance, and keep our immune systems strong.
"We were there in the 80s for the crash, and this is definitely crashier." John and Brenda Romero reflect on the industry crisis
The pair have had to dramatically downsize their studio since the money dried up – but they're determined to keep on coding to the bitter end
Sick of empty VR app stores? Google's new AI tool lets you build VR apps in under a minute
Gemini's new Vibe Coding XR could finally solve the Android XR content problem.
Google's Agent Smith helps its employees with AI-driven coding
Google employees are playing with Agent Smith, an autonomous coding agent, as cofounder Sergey Brin pushes an agent-driven future.
Google's Agent Smith helps its employees with AI-driven coding
Google employees are playing with Agent Smith, an autonomous coding agent, as cofounder Sergey Brin pushes an agent-driven future.
To keep climate science alive, researchers are speaking in code
Words considered "woke" are vanishing from National Science Foundation proposals. Grist tracked the changes.
Chattanooga allergist warns smoke and pollen can worsen health for some during Code Orange
You may have noticed a haze over the Chattanooga area Thursday due to the Code Orange Alert caused by nearby wildfires.Poor air quality can be harmful forcerta
Eleven UC Berkeley faculty members elected fellows of the American Association for the Advancement of Science
The newly elected AAAS Fellows include a tech pioneer, the author of a book on nature’s poisons and a neuroscientist who can decode what you are seeing from your brain wave activity.
Decoding the Visual World
Learn how NSF's long-standing investments helped computers learn to identify and interpret images, advancing technologies now integral to people's daily lives.
Cape Cod fishermen take science offshore to count monkfish
Cape Cod fishermen have been helping scientists track monkfish. Here’s why it matters for the fishery, the fish, and your seafood plate.
Synthesia's top lawyer vibe-coded an AI version of himself
Gabe Stern, Synthesia's general counsel, says he's developing a lawyer avatar built to negotiate his company's contracts.
Cloudflare’s new Dynamic Workers ditch containers to run AI agent code 100x faster
Cloudflare says dynamically loaded Workers are priced at $0.002 per unique Worker loaded per day, in addition to standard CPU and invocation charges
Claude Code can now take over your computer to complete tasks
But Anthropic urges caution as "research preview" safeguards "aren't absolute."
Anthropic’s Claude Code and Cowork can control your computer
Its only a research preview for now.
Earth’s Strangest Magnetic Era: Scientists Decode the Ediacaran Mystery
Ancient rocks reveal that Earth’s magnetic field during the Ediacaran may not have been chaotic after all.
CelebrateOne secures $3.39M grant to fund for maternal health in Columbus
CelebrateOne secured a $3.39 million grant to fund 15 organizations expanding maternal health services in Franklin County.
Claude can now automate your entire desktop, but with a serious limitation
It's likely a temporary one, though.
The Monday Outlook: Project Hail Mary and the Science Behind Blockbuster Sci-Fi
Project Hail Mary is the latest sci-fi blockbuster to stretch the bounds of audience imagination and stir the curiosity of real scientists. But the science driving films like Project Hail Mary, Interstellar and The Martian isn’t all fictional: at UChicago, researchers exploring the cosmos and decoding the origins of life are making discoveries that would feel right at home on the big screen. This week's Monday Outlook features scientists from UChicago and Argonne National Laborat
Ruth’s Chris enforces business casual dress code at restaurants
The ‘Nightcap’ panel discusses Ruth’s Chris’ enforcement of a business casual dress code and the viral reaction on social media on 'Fox News @ Night.'
Firefox 149 Now Available With XDG Portal File Picker, Rust-Based JPEG-XL Decoder
Firefox 149.0 release binaries are now available with a wide assortment of improvements for this month's update to the cross-platform Mozilla web browser solution.
Companies Aren’t Ripping Out Business Software for AI. Here’s What They’re Doing Instead.
Tech leaders at large corporations say that, for now, they’re vibe-coding their own small, custom apps, and putting pressure on their software vendors.
Ohio lawmaker proposes election board changes after Delaware County dispute
Dispute at the Delaware County Board of Elections prompted a state lawmaker to propose changes to how county election boards work.
Cursor acknowledges its new low-cost coding model has Chinese roots
Cursor says its new coding model builds on Kimi K2.5, a Chinese model it didn't mention at launch.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Far-left activists stay in 5-star Cuban hotel as island suffers total blackout
CodePink sponsored flights to Cuba to protest President Donald Trump's sanctions, but the group faced backlash for staying in luxury hotels.
Scientists Uncover Hidden “Second Layer” in Human DNA
A newly identified cellular system monitors subtle variations in genetic coding, hinting at a hidden level of control over how genes are expressed.
Core operating profit rises 4% as net profit holds steady, with full-year dividend maintained at HK35 cents
March 22, 2026 -- The Hong Kong and China Gas Company Limited (stock code: 0003, hereinafter referred to as “the Group”) has announced its 2025 ...
Halide co-founder is suing former partner for bringing source code to Apple
Startup drama.
People inside Microsoft are fighting to drop Windows 11's mandatory Microsoft Account requirements during setup
Microsoft's big sweeping set of improvements coming soon to Windows 11 don't address its controversial Microsoft account requirements, but that might soon change.
Amazon developing new AI-driven smartphone years after Fire Phone flop: report
Amazon is reportedly developing an AI smartphone codenamed "Transformer" with Alexa integration over a decade after its failed Fire Phone launch.
Amazon developing new AI-driven smartphone years after Fire Phone flop: report
Amazon is reportedly developing an AI smartphone codenamed "Transformer" with Alexa integration over a decade after its failed Fire Phone launch.
Downtown Chico business owner voices concerns over street closures for events
A DOWNTOWN CHICO MERCHANT IS EXPRESSING CONCERN OVER THE IMPACT OF STREET CLOSURES FOR EVENTS -- ON THEIR BUSINESS. ACTION NEWS NOW REPORTER BELLA BARBOSA REPORTS FROM DOWNTOWN CHICO { "@context": "https://schema.org", "@type": "VideoObject", "name": "Downtown Road Closure Dilemma", "description": "A DOWNTOWN CHICO MERCHANT IS EXPRESSING CONCERN OVER THE IMPACT OF STREET CLOSURES FOR EVENTS -- ON THEIR BUSINESS. ACTION NEWS NOW REPORTER BELLA BARBOSA REPORTS FROM DOWNTOWN CHICO", "thumbnailUrl": "https://bloximages.newyork1.vip.townnews.com/actionnewsnow.com/content/tncms/assets/v3/editorial/c/47/c47e26d6-03c3-5f35-bf49-37925ab603d7/69bdedc4eb57d.image.jpg", "uploadDate": "2026-03-20T17:45:00-07:00", "contentUrl": "https://cdn.field59.com/KHSL/1774053903-6e1ef36dd09fbebf020833aee86b60da3b3cca3f_fl9-720p.mp4" } CHICO, Calif. - A downtown Chico business owner is voicing concerns about the impact of street closures for events on local shops. Leann Powell, owner of The Peddler’s Closet, expressed concern about events closing down streets downtown and bringing in food trucks and other shops’ products that directly compete with the brick-and-mortar stores in downtown Chico.Powell said an upcoming event held on a Saturday has brought up concerns for her and other business owners downtown, due to it being a busy day for businesses. "We're already struggling, and then to bring in more businesses on top of our businesses and shut our streets down is absolutely devastating," said Powell.Powell noted a decline in business during events like the Thursday Night Market, where street closures allow outside vendors to set up shop. She shared that while organizers for these types of events often offer booths to local businesses, it does not alleviate the burden."I don't really feel like that's a solution because you're bringing in other businesses, you're shutting the streets down. Yes, we can go down and set up a space, but then you've gotta pay somebody to run that space, plus run your own business for the day, and it's really not, it's really not helpful for us," said Powell.Applying for a street closure permit in Chico involves approval from the Public Works Department, the Chief of Police, and the Fire Chief. Permits can be denied only under a handful of circumstances, such as interference with first responders, previously scheduled construction, or existing permits for the same space.Mayor Kasey Reynolds addressed the issue, saying the city council has tasked staff with reviewing the municipal code for street closure permits with the goal of finding ways to minimize negative impacts on local businesses during events.Reynolds mentioned that any recommended changes might require further direction from the city council, depending on the extent of any changes recommended. googletag.cmd.push(function() { googletag.display('ad-1514992'); });
Scientists just found a hidden 48-dimensional world in quantum light
A routine quantum optics technique just revealed an extraordinary secret: entangled light can carry incredibly complex topological structures. Researchers found these hidden patterns reach up to 48 dimensions, offering a vast new “alphabet” for encoding quantum information. Unlike previous assumptions, this topology can emerge from a single property of light—orbital angular momentum.
Data Science Use Cases: 15 Real-World Applications Transforming Enterprise Operations
Explore 15 enterprise data science applications across manufacturing, healthcare, retail, and finance — with case studies, code examples, and proven outcomes.
'Keep it Kountry': How Kountry Wayne refused to code-switch and became comedy's most authentic voice
The Georgia-born comedian stands out through his authentic Southern voice and unconventional family dynamic as a father of 10, now breaking into film.
Ohio airman's father says his son's death should not be 'political springboard'
Charles Simmons son was killed in a March 12 crash in Iraq. The grieving father said he doesn't want his son's death used as a talking point.
Valve releases SteamOS 3.8 preview with Steam Machine support and wider handheld compatibility
Valve SteamOS 3.8 preview is here Valve has released SteamOS 3.8.0 Preview, codenamed "Second Clutch," for the Steam Deck Preview channel. The update adds
Cracking the human simulation code: Aaru co-founders on refining the science of prediction
Cameron Fink, Aaru co-founder and CEO, Ned Koh, Aaru co-founder and president, and John Kessler, Aaru co-founder and CTO, join 'Squawk Box' to discuss the origins of the company, using AI to predict human behavior with higher accuracy and speed than traditional methods, and more.
Anthropic just shipped an OpenClaw killer called Claude Code Channels, letting you message it over Telegram and Discord
The consensus among early adopters is that Anthropic has successfully internalized the most desirable features of the open-source movement—multi-channel support and long-term memory
Equine Business Code Draft Update now available, survey open
The Washoe County Planning Division has completed a draft of the equine business code, which is available online and can be viewed here: Equine Business Annotated Draft. Planners will host several opportunities in the coming weeks to provide feedback on the draft code. The first is an Equine Business Code Update Webinar that will review the equine business code update process so far, what […]
The Girl at the End of the World: A Gratitude Day Reflection on the Place that Built Our Science
⏱️ 9 min read | This Gratitude Day, March 23rd, we celebrate the extraordinary partnership between HD families, scientists, and caregivers, and reflect on the place that built the science on which we all stand.
Google Shakes Up Its Browser Agent Team Amid OpenClaw Craze
As Silicon Valley obsesses over a new wave of AI coding agents, Google and other AI labs are shifting their bets.
2 Arizona resorts, Hawaiian BBQ spot cited by health inspectors
Two Arizona resorts and one Phoenix Hawaiian BBQ spot were among places cited by health code inspectors in this week's Dirty Dining report.
Maine gubernatorial candidates outline health care visions
The Democratic and Republican primaries are set for June 9 and the general election is set for November 3.
Apple Cracks Down on ‘Vibe Coding’ Apps
Apple has quietly prevented AI vibe coding apps such as Replit and Vibecode, which help people create games and other applications, from releasing updates to their mobile apps on the App Store unless they make modifications, according to several people with knowledge of the situation. The ...
Scientists race to decode data from Europe’s vanishing glaciers
Glacier ice contains valuable information about the climates of the past. Researchers are scrambling to study it before it's too late.
AMD Medusa Point Leak Shows 10 “Zen 6” Cores At 2 GHz Faster Than 10 “Zen 5” Cores at 5 GHz
AMD's Medusa Point "Zen 6" APUs have leaked out once again at Geekbench, showcasing even higher performance than earlier.
5 lessons from a weekend vibe coding class as a non-technical person
I joined a weekend vibe coding class and built apps in two mornings. As a non-technical builder, I learned five lessons.
New Albany looks to annex, rezone 106 acres for business park expansion
A developer seeks to annex and rezone more than 100 acres in Licking County into New Albany, expanding the business park near Intel.
Democrats like Markwayne Mullin but that doesn’t mean they’ll vote for him for DHS secretary
In his early days in Congress, Markwayne Mullin tried pairing his suit jacket and tie with a pair of jeans on the House floor. Then-House Speaker John Boehner reprimanded the young Republican for breaking the dress code.
The voice of a long ago whale could lead scientists to a breakthrough
Researchers on Cape Cod, Mass., recently discovered the oldest known recordings of whale sounds and believe the discovery could help scientists understand how the animals communicate
AI still doesn't work very well, businesses are faking it, and a reckoning is coming
interview: Codestrap founders say we need to dial down the hype and sort through the mess
OpenAI to cut back on side projects to focus on core business, WSJ reports
ChatGPT-maker OpenAI's top executives are finalizing plans for a major strategy shift to refocus the company around coding and business users, the Wall Street Journal reported on Monday.
Exclusive | OpenAI to Cut Back on Side Projects in Push to ‘Nail’ Core Business
A top leader urges staff not to be distracted by “side quests” as the company plans a shift of resources to coding, enterprise businesses.
New Book Helps Teachers Implement Science of Reading in Their Classrooms
Aldeman: Practical guide offers concrete tips and embedded QR codes that link to videos of teachers putting those strategies into practice.
Bcachefs 1.37 Released With Linux 7.0 Support, Erasure Coding Stable & New Sub-Commands
Kent Overstreet today released Bcachefs 1.37 as the newest feature release to this out-of-tree file-system driver and user-space tooling for this next-gen, copy-on-write file-system.
Home for Families launches on-site mental health support for clients
Columbus nonprofit Home for Families has partnered with Hidden Roots Mental Health to bring on-site mental health services to clients.
Belinda M. Paschal covers features, entertainment for the Dispatch
Dispatch features reporter Belinda M. Paschal, whose focus is arts and entertainment, gives an update on what's happening on her beat.
The founder of $100M brand Late July and Nixie started selling $1 cookies at 12 and learned the snack trade from the founder of Cape Cod chips—her dad
Nicole Bernard Dawes, the founder of Late July and Nixie, got her start in business selling $1 cookies at local delis—the lessons she learned from the $500 summer hustle led to multimillion-dollar success.
Will the Indus Valley script ever be deciphered?
The Indus Valley script dates back around 4,000 years but has yet to be deciphered. Can AI help decode it?
Perplexity's Aravind Srinivas Says AI Could Change How Computer Science Is Taught
Aravind Srinivas endorsed a post on X by a physics and AI/ML student that argued large language models (LLMs) are automating routine coding tasks.
Linux Finally Catches Up to Windows with a Game-Changing Performance Feature
For years, the Linux kernel’s scheduler has been world‑class at balancing loads, yet it missed a crucial, cache‑aware instinct. In modern multi‑core systems, that gap can turn into measurable latency, especially when threads bounce between cores that don’t share the same cache. A new upstream feature, often called Cache Aware Scheduling, is now set to change that equation. A cache‑savvy scheduler arrives At the heart of any OS, the scheduler decides which thread runs where and for how long. In modern CPUs, small private caches (L1 and L2) sit beside each core, while a larger Last Level Cache (LLC, typically L3) is shared among groups of cores. When a task migrates across LLC boundaries, its warm data may vanish from the cache, forcing slower trips to main memory. Cache Aware Scheduling keeps related tasks close to their shared LLC, reducing destructive migrations. By respecting cache topology, the kernel minimizes cold‑start penalties and preserves locality that many workloads desperately need. The result is less thrashing, fewer memory stalls, and more consistent throughput. "Keep tasks close to their data, and the system will keep performance close to its peak." Why this narrows the Windows gap Windows has long leaned on topology‑aware, cache‑sensitive heuristics, especially since the Windows 10 era. That advantage helped Microsoft handle hybrid designs with P‑cores and E‑cores, plus complex cluster and NUMA layouts. With cache awareness integrated upstream, Linux brings parity to this vital dimension, without sacrificing its trademark flexibility. The Linux approach remains deeply configurable, reflecting the ecosystem’s breadth across servers, desktops, and embedded devices. It layers atop existing NUMA‑balancing and energy‑aware logic, refining placement rather than reinventing the wheel. Crucially, it aligns scheduling with the hardware’s real shape, not just with abstract CPU counts. Real‑world gains and who benefits Early tests on Intel Sapphire Rapids platforms point to gains in the 30–45% range for select workloads. Those wins appear in cache‑sensitive tasks like in‑memory analytics, high‑thread compilation, and microservices with tight working‑sets. Games and latency‑bound engines can also feel steadier frame‑times, especially when threads share hot assets. The benefits extend to AMD’s 3D V‑Cache parts, where keeping threads near enlarged cache slices prevents needless misses. Hybrid x86 designs with performance and efficiency cores further profit when cache and core roles are scheduled in concert. Even handhelds running SteamOS can squeeze more out of limited power, translating cache locality into smoother play. Key advantages include: Lower end‑to‑end latency Fewer expensive misses to RAM Better multi‑socket and NUMA behavior Improved energy efficiency More predictable QoS under mixed loads Stronger scaling on dense servers Caveats, tuning, and rollout No scheduler change is purely free, and trade‑offs still exist. Favoring locality can reduce cross‑cluster balance if limits are set too tight. Likewise, fairness and utilization must remain healthy, especially under heterogeneous, bursty workloads. Linux’s implementation is designed to be measured and tunable, not a blunt instrument. It cooperates with energy‑aware scheduling for mobile efficiency, and with NUMA‑balancers on big iron. Expect architecture‑specific refinements as vendors surface richer topology hints and cache‑sharing maps. Upstream integration has begun, with broad distribution adoption likely over the next cycles. Many users will encounter the change through standard kernel updates in 2025–2026, depending on distro cadence. Server‑class kernels may enable or tune it sooner for targeted fleets where cache locality is money in the bank. How to think about performance impact Cache Aware Scheduling amplifies gains when your workload is both CPU‑bound and cache‑sensitive. Think tight inner loops, hot code paths, and datasets that fit snugly in shared LLC. It’s less dramatic for I/O‑bound services or memory‑hungry tasks that blow past cache capacity. Still, even modest locality improvements often translate into smoother tail‑latency, which is where user experience and SLAs typically break. Developers can further help by pinning related threads, batching work, and aligning data to reduce cross‑cluster chatter. The scheduler’s new awareness works best when applications expose good hints. The bottom line By understanding and honoring cache topology, Linux removes a subtle yet costly bottleneck. The kernel’s smarter placement keeps hot data hot and work near where it belongs. That narrows a long‑standing gap with Windows, while preserving the openness and tunability Linux champions. For gamers, creators, and operators, the payoff is practical: more consistent frames, faster builds, and snappier services. For the ecosystem, it’s another step toward hardware‑savvy scheduling that turns transistor complexity into real‑world speed. And for Linux itself, it’s a timely upgrade that matches today’s silicon with tomorrow’s expectations.
Scientists discover ancient DNA “switches” hidden in plants for 400 million years
Scientists have uncovered an enormous hidden archive of plant DNA that has endured for more than 400 million years. By comparing hundreds of plant genomes, researchers identified more than 2.3 million regulatory DNA sequences that act like genetic switches, controlling when and how genes are activated. These sequences, known as conserved non-coding sequences (CNSs), were detected using a new computational tool called Conservatory.
New Business: Robotics and AI rule at Hudson coffee drive-thru; new T-Bones open in Hudson
The best thing about the new coffee drive-thru in Hudson might be the fact there’s no need to scan QR codes or tip. That’s because behind the scenes robots are
Carter's relationship included dinner with OSU leaders, business lobbying
Former Ohio State President Ted Carter tried to leverage his leadership roles to help a woman he was involved with romantically, sources confirmed.
Microsoft just fixed my BIGGEST gripe about the Windows 11 setup experience
The latest Windows 11 preview build introduces the ability to specify a custom user directory for your account, something both macOS and Linux have supported for decades.
Was your Cape Cod home or business damaged in the Blizzard of '26? MA wants to know.
The deadline for the blizzard damage survey, which will help determine if the region qualifies for disaster assistance, is March 16.
PRWeek US Awards 2026: Best in Sports and Entertainment
Winner: Coca-Cola and Ogilvy; Honorable mention: Cetaphil and Lippe Taylor /Prompt
An odd-nosed crocodile ate our prehistoric ancestors
‘Lucy’ probably needed to watch her back.
Health systems use AI to break down language barriers in patient discharge notes
Translation systems are "trained to understand medication dosages, medical codes and other clinical terminology so the AI model works as it should," an Oracle engineer explained at HIMSS26.
Xbox unveils first tech details of its next generation console, codenamed Project Helix
Xbox has revealed limited technical details about its next console, codenamed Project Helix.
Amazon tightens code guardrails after outages rock retail business
Internal documents obtained by Business Insider show how Amazon is reacting to a series of recent outages related to software coding issues.
Greenway Health unveils AI-enabled EHR-RCM platform
Called Novare, it offers ambient note-taking, voice-activated chart search, agentic task helpers, intelligent coding suggestions, automated prior authorization, real-time benefit checks and more.
'Impractical Jokers' star dines at Cincinnati restaurant
The comedian stopped at a Cincinnati restaurant while on tour in Cincinnati.
Greenway Health debuts AI-enabled EHR-RCM platform
Called Novare, it offers ambient note-taking, voice-activated chart search, agentic task helpers, intelligent coding suggestions, automated prior authorization, real-time benefit checks and more.
How game day outfits change — and stay the same
The unspoken dress code for football games at UNC leans toward SEC attire, despite it being an ACC school.
Ohio AG Dave Yost says couple used fake rescue to bankroll puppy business
An animal rescue in southern Ohio said it would help dogs find homes. The owners pocketed the money instead, according to a lawsuit.
New entertainment venue to open in former El Camino Inn
A new entertainment venue, The Valley, is opening in downtown Columbus, taking over the former El Camino Inn space.
Blue Cross Blue Shield says data back up claim that AI is driving up medical bills
A new data analysis from Blue Cross Blue Shield shows how AI coding may be driving up the cost of health care.
What crocodile bones teach us about dinosaurs
Paleontologists have often determined how old a dinosaur was by counting the growth rings in its bones. Just like with trees, it was thought that each ring corresponded to a single year of age. But researchers who studied crocodiles at an outdoor recreation center near Cape Town appear to have poked a hole in that approach. In the crocodiles, which are some of the closest living relatives of dinosaurs, there was more than one growth ring laid down per year. The results contribute to a growing debate over the best way to age animals.Read more of freelance science reporter Ari Daniel’s story here.Interested in more on the future of science? Email us your question at shortwave@npr.org.Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.
ColorStack provides computer science students with community and competitive edge
Binghamton University’s chapter of ColorStack helps students learn skills in computer science and supports career development, all while fostering a supportive community. Founded in 2023,...
Bob on Business: Texas expected to be world’s largest data center market by 2030
Also, which ZIP codes saw hot home sales in 2025?
PSA: Pokémon Pokopia Players Can Now Tour The Developer's Cloud Island
You'll need a code and Switch Online sub to visit
Transparent Tribe Uses AI to Mass-Produce Malware Implants in Campaign Targeting India
Transparent Tribe uses AI tools to mass-produce polyglot malware targeting India using Slack, Discord, and Google Sheets C2.