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Authentic Signs Definitive Agreement to Acquire Care Bears
Authentic Brands Group, a global brand and entertainment platform, today announced it has signed a definitive agreement to acquire the intellectual property of Care Bears, one of the world's most beloved and enduring family entertainment franchises.
Supreme Court upholds birthright citizenship, rejecting Trump’s proposed limits
WASHINGTON (AP) — A divided Supreme Court on Tuesday upheld a broad conception of birthright citizenship, rejecting President Donald Trump’s executive order declaring that children born to people who are in the United States illegally or temporarily are not American citizens. The justices relied on a long-settled understanding of the 14th Amendment, adopted after the […]
Who’s building and who’s buying in Greater Baton Rouge
Here are the latest issued permits and property transactions in East Baton Rouge and Ascension parishes. East Baton Rouge Parish The East Baton Rouge Parish Sheriff’s Office purchased the pr… Already an INSIDER? Sign in. Already an INSIDER? Sign in
Business is good at the Camillus Costco. It asks town for OK to make a move
The proposal is being reviewed by the town of Camillus planning board.
US bill requiring paid games to be playable after they shut down has failed to pass a Senate vote
Stop Killing Games says it will try again with “the funding to do this properly”…
The Satire, Autograph Collection | The Hotel Collection
Discover The Satire, Autograph Collection an American Express Travel Luxury Property. Learn More About The Offerings & Features of The Satire, Autograph Collection in Alexandria, Virginia US.
Vatican Observatory addresses one of science’s greatest enigmas: quantum gravity
A conference addressed the subject of quantum gravity with regard to the incompatibility of quantum mechanics with general relativity, presenting a challenge for researchers to propose solutions.
Nation’s largest industrial landlord bets $100M on Chicago warehouse demand
The project is a show of confidence by one of the biggest industrial property companies that the Chicago-area warehouse market has pent-up demand.
Company that made a Steam Machine wrap based on Valve intellectual property without asking forced to take it down
Dbrand's Portal-themed Companion Cube wrap for the Steam Machine won't be seeing the light of day for a very good reason.
Developer addresses community concerns around Franklin youth sports complex project
The project, proposed by developer BLVD Capital, would transform Brownland Farm, a 233-acre property on Hillsboro Road just outside downtown Franklin, into “The Banks at Brownland.”
Columbus man arrested following massage business investigation
The Columbus Police Department has arrested a man following an investigation into allegations of inappropriate conduct at a local massage business.
'Cruel, heartless': Critics raise health concerns with proposed immigrant detention facility
Critics warn that plans for a proposed immigration detention center in Salt Lake City may not be dead and are raising healthcare concerns if such a facility is built.
Comcast to Spin Off NBCUniversal Into Standalone Entertainment Company
Comcast announced today that it plans to separate NBCUniversal into its own publicly traded entertainment company, marking one of the biggest corporate restructurings in the company's history. Under the proposed split, NBCUniversal will become an independent entertainment company, separating from C
BlueCross BlueShield of VT pulls its proposed lower-cost, higher-deductible health plans
The insurer said the Green Mountain Care Board’s delayed approval of the plans left them with little time to prepare.
Scientists Slam Trump Rule Change
Dr. Esen Sefik moved from Istanbul to New Haven 20 years ago because she believed the U.S. was the best place to do scientific research. Now, her advisees are wondering whether to stay in their home countries instead. Sefik described the U.S.'s changing research climate on Monday during a press conference about a proposed rule by the Trump administration that would require a political appointee to approve all discretionary federal grants.
THE WEEK OF JUNE 29, 2026
- NSF proposes grant policy changes - Republicans urge DOE to limit lab access - DOD highlights aging labs
Colorado Supreme Court: Redistricting plans for 2028 election cannot proceed under state constitution
The Colorado Supreme Court blocked all attempts at redrawing congressional district boundaries for the 2028 election from reaching the ballot on Monday, concluding each of the proposed ballot measures violated the constitutional single-subject requirement. The court considered five distinct, but related, ballot measures. Three proposals would have redrawn U.S. House of Representatives districts to give […]
Congress wants to ban AI companies from selling your health data
The new proposal bans selling health and location data info — including data entered into your favorite AI chatbot.
Malik Beasley reportedly indicted as part of sports-betting scheme involving point shaving, prop bets
Malik Beasley was first announced as part of a federal investigation last June.
Nine-year NBA veteran indicted on federal sports gambling charges
Veteran NBA shooting guard Malik Beasley has been indicted on federal charges for gambling related to a sports betting scheme, such as point shaving and prop bets, his attorney Steve Haney told ESPN. on June 29. According to Shams Charania,…
Meccha Chameleon Fans Bring The Hide-And-Seek Game To Real Life
The painted prop hunt game has escaped the digital space and entered the real one
Political Control of Research Funding Threatens Sound Science
Decades of federal research funding have led to breakthroughs in medicine, technology, and environmental science. A new OMB proposal aims to derail all of this through political interference.
Benevolent, manufacturing facilities: See 20 latest business, apartment, land sales ($30K to $1.4M)
See a list of property sales in Onondaga County other than residential homes.
Apple accuses India of 'copy-pasting' rivals' claims in antitrust investigation
Apple has accused Indian antitrust investigators of "copy-pasting" its rivals' claims and failing to properly conduct its own investigation in concluding the U.S. tech giant breached competition laws, calling for the findings to be quashed, regulatory papers reviewed by Reuters showed.
Martin County residents keep pressing state officials for funding to reopen hospital
ECU Health has proposed converting Martin General into a Rural Emergency Hospital under a federal designation.
Ingredion plans global Benicaros prebiotic expansion across gut and immune health applications
Ingredion highlights that its recent acquisition of the Benicaros prebiotic is a strong strategic addition to its Healthful Solutions portfolio, supporting the company’s formulation versatility alongside expansion of health-forward and clean label ingredients. The company purchased the patented prebiotic fiber, made from upcycled carrot pomace, from NutriLeads earlier this month. With the deal, Ingredion obtained full ownership of all intellectual property, trademarks, human clinical trials, and know-how related to manufacturing Benicaros.
BUSINESS PERSPECTIVES: BerkShares Business of the Month is Bizalion’s Fine Food in Great Barrington
Bizalion’s Fine Food co-owner Jean-François Bizalion emphasizes the unexpected connections between Provence and the Berkshires, the merits of Volcanic grown olive oil, and the importance of gaining fresh inspiration through travel and of valuing your community.
VSP Vision Announces Winner of Propel Student Business Challenge Scholarship
RANCHO CORDOVA, Calif.—VSP Vision, in collaboration with the Student Optometric Leadership Network (SOLN), today announced that Mason Martin, a student at the University of Alabama at Birmingham School of Optometry, is the winner of the 2026 Propel Student Business Challenge Scholarship, powered by PECAA. Martin, who was awarded the $10,000 scholarship and a travel grant to attend the SOLN conference in Denver, is the first first-year student at the school to receive this honor, the announcement said. VSP said his standout submission featured a thoughtful, patient-centered private practice business plan.
Atlanta businesses push back on proposed liquor license pause as leaders seek to curb Edgewood Avenue violence
Edgewood Avenue business owners back public safety improvements after recent violence, but some say pausing new liquor licenses won't solve crime's root causes.
Bob on Business: Fort Worth Stockyards auction barn seeing new life as studio, live venue
Also, more Stockyards-area property on the market; area CEO honored; pawnshop deal; and another acquisition.
Ted Cruz bill to regulate college sports in NIL era advances
The Texan said he hopes the proposed changes, written with a Democratic senator, can save athletics from a stark separation between the haves and have-nots.
Efzimfotase alfa demonstrated improvements in bone health in treatment-naïve pediatric patients with hypophosphatasia achieving median difference of 1.67 vs placebo in RGI-C Score at week 25 in MULBERRY Phase III trial
Positive results from the MULBERRY Phase III trial showed that efzimfotase alfa (ALXN1850), an investigational enzyme replacement therapy, demonstrated a statistically significant and clinically meaningful improvement in bone health in children (2 to
Healthcare groups clash over proposed California billionaire tax
California voters in November are set to decide if the state's billionaires should face a new tax on their assets in order to fund healthcare programs.
Healthcare groups clash over proposed California billionaire tax
California voters in November are set to decide if the state's billionaires should face a new tax on their assets in order to fund healthcare programs.
Rescheduling marijuana would put politics ahead of science
The Drug Enforcement Administration is considering a proposal to move marijuana from Schedule I to Schedule III of the Controlled Substances Act, which would recognize all cannabis products as havi…
Rescheduling marijuana would put politics ahead of science
The Drug Enforcement Administration is considering a proposal to move marijuana from Schedule I to Schedule III of the Controlled Substances Act, which would recognize all cannabis products as havi…
California Politics 360 full episode | What to expect on California's November ballot
KCRA 3 Political Director Ashley Zavala leads conversations on California's November ballot questions, including the proposed billionaire tax.
'All INdiana Politics'
U.S. Sen. Todd Young has said that a proposed $300 billion payment to Iran would not be funded by American taxpayers, and that any ceasefire with Iran must be contingent on the dismantlement of its nuclear program, while Indiana Senators Young and Banks have split on a housing bill now awaiting President Trump's signature.
Linux 7.3 To Introduce DRM "Color Format" Property With AMD GPU Driver Support
While the Linux 7.2 kernel merge window is only ending later today to cap off the feature work on this next version of the Linux kernel, already for the Linux 7.3 kernel cycle later in the year there is one notable feature on the way: the DRM color format property is being introduced and being first supported by the AMDGPU kernel graphics driver.
National City weighs business tax overhaul amid mounting budget pressures
Council to hear proposal June 30. It faces significant opposition from business community.
Reporter talks environmental, health impacts of mining efforts near Boundary Waters
WTIP spoke to Benji Jones, Senior Correspondent at Vox Media, about what environmental and health experts are saying about the proposed Twin Metals mining project in the Boundary Waters Watershed. Jones’ article “Mining these metals could be a boon for the climate — but there’s one big catch,” is currently available at vox.com. Below is...
UNC, NC State to get millions from sports betting; gambling deductions allowed in budget proposal
Not only would the tax on sports betting operators rise to 23%, but North Carolina would levy taxes on prediction market operators as well under proposals expected to be included in the state budget.
Maryland health insurance rates could rise 13.7% in 2027 under proposal
BALTIMORE — Maryland residents who buy health insurance through the Affordable Care Act marketplace could see higher premiums next year, with insurers requesting an average rate increase of 13.7% for
MS Comic Con 2026: cosplayers, celebrities and fans unite to celebrate beloved characters
Attendees decked out in costumes and homemade props from their favorite TV shows and movies gathered at the Mississippi Trade Mart for Comic Con 2026
Star Wars Eclipse in danger of cancelation, claim striking Quantic Dream developers
Workers protested in Paris over proposed layoffs at the Star Wars Eclipse studio…
Ryman Hospitality Addresses Reports About Opry Entertainment Group
Ryman Hospitality Properties addressed recent media reports regarding its Opry Entertainment Group business.
CARE AT HOME GUARANTEE CORPORATION FILES PATENT APPLICATION FOR PROPRIETARY BUSINESS MANAGEMENT SYSTEM
Miami, FL, June 27, 2026 (GLOBE NEWSWIRE) -- CARE AT HOME GUARANTEE CORPORATION ('the Company'), a Florida-based Senior Care Solutions company, ...
J. William Fulbright, proponent of cultural exchange, left complex legacy across politics, education
As the Vietnam War heated up, U.S. Sen. J. William Fulbright became uncomfortable with American involvement in the conflict.
J. William Fulbright, proponent of cultural exchange, left complex legacy across politics, education
As the Vietnam War heated up, U.S. Sen. J. William Fulbright became uncomfortable with American involvement in the conflict.
Downtown Largo could become an open-container entertainment district
Downtown Largo could allow open-container drinking, outdoor entertainment and live music under a proposed entertainment district.
How PENN’s US$360 Million Aurora Resort Shift At PENN Entertainment (PENN) Has Changed Its Investment Story
PENN Entertainment has opened the US$360 million Hollywood Casino and Hotel Aurora, replacing its former Fox River riverboat with a 388,500-square-foot, 24/7 land-based resort featuring over 1,000 slots, 50 table games, a sportsbook, 226-room hotel, spa, event center, and extensive dining options. The Aurora project, which created around 700 permanent roles and mirrors PENN’s broader shift into higher-amenity land-based properties, highlights how the company is reinvesting heavily to refresh...
Gavin Newsom opposes a California wealth tax. He’s proposing a national billionaire tax instead
California Gov. Gavin Newsom on Friday proposed a national tax on billionaires that he says is the first part of an “economic reset for America” agenda, which aides explicitly say is part of his considering to launch a presidential campaign.
Why where you live matters for heart health — even in childhood - Baylor College of Medicine Blog Network
Evidence links environmental exposures to early cardiovascular risk, disproportionately impacting marginalized communities like AI/AN youth.
Opinion | Don't apply politics to scientific research
Under recently proposed rules, federal grants could be terminated midstream for reasons having little to do with science or merit.
Proposed Changes to Grant Rules Threaten the Future of Research: Scientists Must Act Now!
The Trump administration is seeking to politicize US federal science funding, but collective action can stop this grantpocalypse from happening.
Billionaire tax, affordable housing: See the measures on California's November ballot
California voters will decide on 14 statewide policy proposals come November, from the controversial billionaire tax to an $11 billion affordable housing bond.
Prosperity Council’s Report Challenges Kotek to Signal That Oregon Is Open for Business
The 15-member panel of business and labor leaders proposed four modest tax code changes, replacing the Climate Protection Program, and some less controversial reforms.
California’s Billionaire Tax Kicks Off a Democratic Civil War
The divisive proposal heads to the ballot after attempts to reach a compromise deal failed.
Trump's DOT clears a pedal-free path for Tesla and Zoox
The NHTSA is proposing allowing the removal of pedals and steering wheels for AVs, making it easier for Tesla and Zoox to pursue alternative designs.
Controversial billionaire tax will appear on November ballot
Proponents of a controversial billionaire tax pledge to making sure it appears on the November ballot to backfill federal healthcare funds.
233-acre Franklin farm could become major youth sports complex
A Nashville Predators-operated ice rink and athletic facility could transform historic Franklin property.
Growing sinkhole in Houston's Third Ward raising safety concerns for business owner, neighbor
A growing sinkhole behind a property on Scott Street in Houston’s Third Ward is raising concerns for a longtime business owner and her neighbor.
Monkey Business: Wild rhesus macaque spotted at Mount Dora hotel
A wild rhesus macaque was spotted at the historic Lakeside Inn in Mount Dora, Florida, spending about 45 minutes roaming the property and attracting attention from guests and staff. The hotel and local businesses responded with humorous, monkey-themed social media content, engaging the community. Wildlife officials cautioned the public not to approach or feed wild monkeys due to potential health risks and encouraged reporting sightings to authorities. The monkey has not returned to the hotel but has been seen elsewhere in downtown Mount Dora.
University, State of Utah sign agreement for proposed south valley health campus
U of U Health has secured land for a proposed health campus that will serve as the health care anchor for the 600-acre master-planned development...
Business Council deliberations continue with four bill drafts
Lawmakers on the Joint Appropriations Committee spent another day diving through the Wyoming Business Council’s dealings. This time, they also reviewed draft bills that would influence how the council operates.
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
SBA’s Proposed Update to the 8(a) Business Development Program: A New Approach to Social Disadvantage
On June 11, 2026, the Small Business Administration (“SBA”) published a proposed rule that would fundamentally alter how individuals qualify as “socially
Proposed CDC science office could tighten political control at agency
Under President Trump, political leaders are exerting more control across federal health agencies.
Strip casino project proposing new 2,000-seat live entertainment venue
Hard Rock is doubling down on its commitment to live entertainment at its $4 billion Strip resort project.
Supreme Court strikes down Hawaii law requiring permission to carry guns in stores and hotels
The high court's 6-3 decision means people can carry guns onto privately owned property like shopping malls and gas stations, unless the owners specifically say guns are banned at their establishments.
Major part of student-loan repayment overhaul is blocked in court
A federal court ruled that the Education Department's proposed borrowing caps for advanced healthcare programs cannot take effect on July 1.
Waterloo's Grout Museum District to demolish its Bluedorn Science Imaginarium amid funding changes
This summer, the Grout Museum District is preparing to demolish its former science center, the Bluedorn Science Imaginarium. The decision was made in the face of funding uncertainty stemming from property tax reform in Waterloo.
How Elifin is reshaping the commercial real estate playbook
Elifin is leveraging a decade's worth of proprietary commercial real estate data as well as artificial intelligence to reshape how properties are marketed, analyzed and sold. The Baton Rouge-based … Already an INSIDER? Sign in. Already an INSIDER? Sign in
Gov. Scott vetoed the Legislature’s latest attempt to lower health insurance costs. What’s next?
Governor Phil Scott's veto of a health insurance bill sparks debate over lowering healthcare costs in Vermont. Discover the proposed alternatives and political tensions.
A new vision for quantum computing takes a big step forward, with new grant
A $4 million National Science Foundation grant will propel the next phase of a Yale-led project to build a quantum computer with an innovative new design.
Psychedelic Science 2027 Speaker Submission Invites the Field to Bridge Promise and Practice
Psychedelic Science 2027 (PS27) convenes May 3–7, 2027, at the Colorado Convention Center in Denver under the theme “Bridging Promise & Practice”PS27’s speaker submission is now open through Friday, September 18, with no planned extensionsPS27 welcomes proposals across science, therapy, policy, culture, industry, the humanities, spirituality, connected movements, and the wisdom traditions that have carried this work for generations DENVER, June 25, 2026 (GLOBE NEWSWIRE) -- The Multidisciplinary
David P. O'Brien
About five years ago, David P. O'Brien had a comfortable position at Marsh & McLennan Cos., where he held the top post at the financial giant's Louisville, Ky., office. Despite the lofty rank, Mr. O'Brien found himself longing to be at a smaller company that had to work a little harder to land business. That desire led him away from Kentucky five years ago and to Cleveland, where he serves as executive vice president at business insurance agency Oswald Cos. "I left Marsh before it was en vogue," he said, referring to layoffs and defections at Marsh over the course of this year that followed accusations of bid rigging at the big firm. Above all, Mr. O'Brien, 38, wanted to work at a company that relied on its inventiveness, rather than its name, for business. He said he has found that at Oswald. "It causes you to be more creative, to be more resourceful," Mr. O'Brien said. For instance, an Oswald client seeking to do business internationally might be directed to the network of offices abroad run by competitors such as Marsh and Aon Risk Services Inc. "We're going to use whatever access into the market that makes the most sense for our clients," he said. Of course, using such a strategy can be dangerous for Oswald if its client decides to further a business relationship with one of the firms Oswald recommended. "That's the obvious question and why it's nontraditional," he said. "I think if we're good, and if we're bringing value to the client, then there's no risk. I'm not threatened by it." Imaginative business solutions of that type made his career move to Oswald from Marsh worthwhile. "It's very much a challenge," he said. "It helps you keep your edge. I'm all for the competition." John Jacunski, currently vice president and corporate controller at York, Pa., paper company PH Gladfelter Co., met Mr. O'Brien four years ago when Mr. Jacunski was at WCI Steel Inc. in Warren. So impressed was he with Mr. O'Brien's work for WCI that Mr. Jacunski has retained the Oswald executive at PH Gladfelter. "He's a young guy for the position he has, but he's done a great job for us," Mr. Jacunski said. Among his roles at Oswald, Mr. O'Brien leads the firm's client retention efforts and also serves as director of its property and casualty group. "You don't have the same human resources," he said of the job jump to Oswald. "You don't have, obviously, the safety net a big company has." But sometimes, it can be difficult to ascertain individual contributions when working at a big company. "I wanted to be able to see the end results of my work and my efforts," Mr. O'Brien said.
Another roadblock for DOJ campaign against trans health
New bill proposes expanding methadone access, $5.7 trillion on U.S. health care, and more health news from Morning Rounds
ESPN proposes final offseason moves for Detroit Lions
ESPN proposed final offseason moves for the Detroit Lions.
Trump is racing to finish his border wall. Here’s how he is planning to do it
President Donald Trump is accelerating his effort to finish his border wall and setting an ambitious goal of completing it by the end of his administration. He’ll need landowners whose property runs along the US-Mexico border to hand over their land to finish it.
Yankees news: Ryan McMahon to IL with throat infection
Ryan McMahon to IL, Oswaldo Cabrera recalled; a primer for the trade deadline; thoughts on the ABS system, CBA proposal
Assort Health scores $120M series C to scale voice AI agent platform for healthcare
Assort Health picked up $120 million in series C funding, hitting unicorn status, to fuel the company's work building out a voice AI agent platform for healthcare. | Assort Health has a large proprietary specialty dataset built on 190 million patient interactions, 62,000 care protocols and 1.6 million decision pathways.
Ryman Hospitality Properties says it is evaluating future of Opry Entertainment Group
Ryman Hospitality Properties says it is exploring strategic opportunities for its Opry Entertainment Group.
'Stone Crazy' Millwood business owner entices neighbors outdoors with crystal searches
Nowadays, the sole proprietor of Millwood’s Stone Crazy crystal shop is enticing today’s youth to follow in her outdoorsy footsteps— quite literally. Since the pandemic, Jenny Dykes has been leaving crystals from her business along Inland Northwest trails to spur others into exploring public lands.
WATCH: Under proposed rule, USPS won't deliver mail ballots to states that don't provide voter rolls, postmaster general says
Postmaster General David Steiner told a Senate committee Wednesday that, if a proposed rule is adopted, the U.S. Postal Service would withhold mail ballots from states that do not hand over to the federal government lists of people who have requested absentee or mail ballots.
Owner of Grand Ole Opry confirms it may sell country music's most iconic venues
Ryman Hospitality Properties says it is evaluating potential opportunities involving Opry Entertainment Group following recent media reports.
IHSA reacts as lawmakers propose bill requiring oversight on girls' sports impact
A new bill in Springfield would seek to overturn an IHSA decision to change the girls' high school flag football season
Ryman Hospitality Properties, Inc. Addresses Recent Media Reports Regarding Opry Entertainment Group
NASHVILLE, Tenn., June 24, 2026 (GLOBE NEWSWIRE) -- Ryman Hospitality Properties, Inc. (NYSE: RHP) (the “Company”), a leading lodging and hospitality real estate investment trust that specializes in group-oriented, upscale convention center resorts and entertainment experiences, today addressed recent media reports regarding the Company’s Opry Entertainment Group (“OEG”) business. Colin Reed, Executive Chairman of Ryman Hospitality Properties said, “We are incredibly proud of our OEG business an
Propsal to limit lobbying in city of San Diego politics moves forward
The San Diego City Council’s Rules Committee voted unanimously Wednesday to direct staff to begin drafting a proposed ethics reform package aimed at lobbyists and dark money.
Health insurers propose high rate hikes for 2027 Minnesota plans
To find out why and how much it'll burden customers, policy analyst Matt McGough with KFF Health News joined Morning Edition Wednesday.
Bangor council rejects proposed rules limiting ICE cooperation
One councilor left abruptly in protest during a heated discussion over ICE.
Online violence against women in politics: what shapes political party responses to technology-facilitated gender-based violence?
Political parties have a primary role to play in tackling online violence against women and gender diverse politicians. While the prevalence and impact of TFGBV, such as coordinated disinformation campaigns, deepfake image-based sexual abuse or trolling are well documented, many parties are still building their knowledge on how to respond effectively and have not put in place internal practices and policies that respond to the rapidly evolving, poorly regulated digital ecosystem. About the ReportIn order to promote and protect fair and democratic participation in politics, this ALIGN Report explores what political parties are doing in response to TFGBV and what factors shape their action. The findings, based on existing literature and interviews with gender and politics professionals, indicate there are three sets of factors which donors, civil society and practitioners should consider when designing action to support political parties to respond to TFGBV internally. These are: (1) gender norms; (2) socio-political environment; and (3) internal party factors.Key messagesUnequal gender norms are ubiquitous across politics, shaping expectations of leaders to be strong and assertive, and practices of political parties to uphold masculinist values and sustain cultures of silence. These often lead to weak response to TFGBV against women politicians.The socio-political context can incentivise or disincentivise action, depending on the salience of gender issues, which are increasingly weaponised. Electoral competitiveness, domestic laws (i.e. quota requirements), and even the political system or global normative frameworks influence political will to act.Internal party factors that shape responses will vary across countries and contexts, but include: structures to enforce codes of conduct, policies and reporting mechanisms on (TF)GBV, political ideology, extent of centralisation of leadership, and crucially the meaningful participation of women in decision-making positions, not least through internal women’s wings.Party responses can be seen as a spectrum, with actions falling between active discouragement to address TFGBV to commitment to transform unequal norms and practices within the party.About the ToolkitTogether with the report, this ALIGN toolkit offers gender professionals and others working on democratic strengthening a set of guiding questions and reflection prompts to identify which responses could be most effective and suitable in different contexts. These actions can complement other solutions to TFGBV, such as regulations promoting safety by design. The assessment spans a broad range of factors including: (1) different manifestations of gender norms, (2) the socio-political environment and (3) internal party structures.Key messagesPolitical parties are duty-bound to take action internally to respond to the significant threats posed to women members and candidates, including from their own party colleagues, affiliates and political peers.Existing party approaches to TFGBV can be assessed along a spectrum which ranges from active discouragement and passive acceptance to minimal response and transformative change.To generate effective and context-appropriate solutions to TFGBV, it is important to consider how gender norms shape leadership expectations and internal party practices, while also analysing the impact of the socio-political environment. While actions to support women to stay safe online are very common, codes of conduct and measures to strengthen women’s voice and power in the parties are proposed as most transformative solutions.
House speaker looks to reconciliation process to pass Trump's voter ID bill
Johnson suggested tying election integrity proposals to a federal grant program
House speaker looks to reconciliation process to pass Trump's voter ID bill
Johnson suggested tying election integrity proposals to a federal grant program
Upstate NY youth sports coach accused of sending indecent material to children through Snapchat
The 21-year-old faces six charges after allegedly sending inappropriate content to two minors over several weeks.
Entrepreneur Works opens business assistance center in Chester
“We want every business to learn how to properly run a business,” says
EU Proposes Tax Simplification Measures in Bid to Boost Business
The European Union unveiled a new package to overhaul the bloc’s tax rules on Wednesday, the latest effort by Brussels to cut red tape and reduce the regulatory burden on business.
PENN Entertainment Celebrates Grand Opening of Hollywood Casino and Hotel Aurora
WYOMISSING, Pa. & AURORA, Ill., June 24, 2026--PENN Entertainment, Inc. (Nasdaq: PENN) ("PENN" or the "Company") today celebrates the grand opening of Hollywood Casino and Hotel Aurora, the all-new, $360 million state-of-the-art casino and hotel. PENN’s latest land-based property replaces the former riverboat property that operated on the Illinois shores of the Fox River since 1993.
This week in Santa Cruz County business: Capitola Wharf business faces uncertain future; Aptos Village business owners and RTC head to court
A proposed new policy regarding leases of city-owned property has the owner of Capitola Boat & Bait worried her business could be priced off the wharf, Jessica M. Pasko reports in her weekly column.