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Wales vs Norway – Predicted lineup and team news
Wales are set to take on Norway in their third UEFA Nations League group-stage clash this Thursday at Cardiff City Stadium, hoping to get back on the winning trail after a difficult start to their cam...
Taxes from data center electricity helps lower health insurance rates for 200,000 Virginians. There may be a catch to this revenue stream, though.
Democrats celebrated the connection between these two events. However, this could create a scenario where Virginia has a stake in seeing more data centers built.
Broward Health Coral Springs Advances Heart Care with First PFO Closure Using the GORE® CARDIOFORM Septal Occluder
Dr. Pablo Rengifo-Moreno with the team that completed the first PFO closure procedure using the GORE® CARDIOFORM Septal Occluder at Broward Health Coral Springs. Broward Health Coral Springs is proud to announce the successful completion of its first PFO (patent foramen ovale) closure procedure using the GORE® CARDIOFORM Septal Occluder, marking a significant milestone in […]
49ers Emerge as Potential Trade Destination for Cardinals Veteran
The San Francisco 49ers need pass-rush help after losing Nick Bosa for multiple weeks to a calf injury. Even before losing him, the Niners likely still needed help, since Bosa is their only reliable edge rusher. San Francisco did sign veteran defensive end Matthew Judon to the practice squad. Nonetheless, the Niners are rolling the […] The post 49ers Emerge as Potential Trade Destination for Cardinals Veteran appeared first on HEAVY.
Experts say a heart-healthy diet is more about consistency than chasing trends
A new ACC scientific statement looks at how eating well can help with the prevention and management of CVD. Plant-based foods as well as healthy fats and proteins are recommended over foods high in refined starches, added sugars and unhealthy fats.
Overall dietary patterns matter more for heart health than nutrients
A healthy, balanced dietary pattern, rather than one focused on individual nutrients or foods is key to maintaining heart health, according to a Scientific Statement issued by the American College of Cardiology and published in JACC, its flagship journal.
Childhood family environments impact midlife cardiovascular and cognitive health
Doctoral dissertation research investigated how the family environment in childhood affects health in midlife.
Broward Health Medical Center Dedicates Boyce Haller Family Cardiac Catheterization and Electrophysiology Suite, Made Possible by $5.2 Million Family Gift
(L-R): Michelle Thoman, chief operating officer, Broward Health Medical Center, Eileen LaMarca, consultant for the Broward Health Foundation, philanthropist Linda Haller, Shane Strum, president and CEO of Broward Health, Stacy Angier, commissioner on the North Broward Hospital District Board of Commissioners, and Lauri Littleton, associate chief nursing officer, Broward Health Medical Center, cut the ribbon […]
Is there really an afterlife? Here’s what science can — and can’t
The question of what happens after death sits at the edge of science because researchers can study dying brains, people who survive cardiac arrest and unusual experiences near death—but they cannot di...
HEALTH & WELLNESS @ HOME: Cardiologist discusses heart attack risks ahead of winter
Doctor explains why heart attack cases rise in colder months
In Praise of the St Louis Cardinals 2026 Season
Well it’s finally over and on the books for 2026. While the season didn’t end on a very good note, let’s instead talk about what went right. After stripping the roster down to the bolts, old school projections systems and Vegas odds had the Cardinals as one of the worst teams in baseball. Many fans […]
Will his health allow Dodgers' Freddie Freeman to deliver another postseason signature moment?
Because of an ailing right knee, the Dodgers don’t really know what you might see out of Freddie Freeman this postseason.
Ex-NFL player Jack Brewer leads charge to end fines for players using religous, political eyeblack messaging
Jack Brewer met with EEOC officials over the NFL's $6,651 fine on a Cardinals cornerback for wearing "Glory Be 2 God" on his eye black strip.
VCU Health tops off new outpatient heart center in Richmond
The 93,000-square-foot building is part of the health system’s effort to expand outpatient cardiovascular care beyond its downtown Richmond campus.
Annual Go Red for Women luncheon raises awareness about women's cardiovascular health
The American Heart Association's Go Red for Women luncheon is continuing the organization's tradition of raising awareness about the importance of women's cardi
9 Best Fruits to Help Reduce Blood Pressure, Cholesterol and Heart Disease Risk
The soluble fiber in fruit can improve cholesterol, a cardiologist says. Certain fruits show “potent cardiovascular protective action” thanks to their beneficial plant compounds.
UnityPoint Health-Finley Hospital nurses speak out against cutting hours for cardiac procedures
Nurses say they’re frustrated over UnityPoint Health-Finley’s decision to cut hours at its cardiac procedure lab.
Texas Rangers' Corey Seager finished the season with a bone spur in his elbow
Chris Young, the team's president of baseball operations, said Monday that Seager had the issue for a couple of months.
Two different views on Amendment 1, the abortion/reproductive health amendment on Virginia’s ballot
Virginians are voting on three proposed constitutional amendments.
Caribbean Diet: Traditional Foods, Nutrition, and Cardiometabolic Health
Traditional and neo-traditional Caribbean food patterns emphasize locally produced plant foods, roots, legumes, fruits, and seafood, with observational evidence linking these patterns to more favorable cardiometabolic profiles. Nutrition transition, import dependence, changing food practices, and structural pressures are reshaping these diets, highlighting the potential value of culturally relevant and locally resilient food systems.
Shaken Baby Syndrome: Junk science or not? When lawyers set scientific standards
Shaken Baby Syndrome has increasingly been branded “junk science,” not because the medical consensus has disappeared, but because courts, some expert witnesses, and the media have created disputes over how these injuries occur. The real question is not whether every SBS prosecution is correct, but whether uncertainty in an individual case justifies discarding a diagnosis supported by a substantial body of medical evidence.
Opioid settlement funds could bridge some health gaps
Back when now-Gov. Maura Healey was the Massachusetts attorney general, in July 2021, she sued opioid distributors, manufacturers, and pharmacies for their prescription practices, which the state argued contributed to a national opioid crisis. What resulted was a settlement of more than $1 billion from opioid-makers Johnson and Johnson and opioid-distributors McKesson, Cardinal, and AmerisourceBergen. […]
7wire Ventures Presents: Top of the Ladder Featuring Karoo Health Co-Founder & CEO Ian Koons
In our latest Top of the Ladder feature, we sat down with Ian Koons to discuss his path into healthcare, why cardiology has resisted value-based care for so long, what it means to build infrastructure rather than another app, how Karoo wraps care around patients between appointments, and where he sees the future of cardiovascular care.
Forest landscapes and birdsong soundscapes have independent physical health benefits
A new study finds that exposure to birdsong soundscapes or forest landscapes reduces physiological stress. These findings of physical health effects complement previous research showing mental health ...
Marvin Harrison Jr. with three grabs
Arizona Cardinals WR Marvin Harrison Jr. had three catches for 40 yards in the Week 3 loss to the San Francisco 49ers Sunday.
Tyler Allgeier invisible in Week 3
Arizona Cardinals RB Tyler Allgeier had just two carries for -1 yard and four catches for 10 yards in the Week 3 loss to the San Francisco 49ers.
New framework maps the complex link between psychological status and cardiovascular health
CVD remains the leading cause of death worldwide, while the global burden of mental disorders continues to rise.
NC State a 6.5-point underdog to Louisville
NC State dips back into conference play with the toughest opponent on its schedule this season, the Louisville Cardinals. It would have been a good idea to come into this one with a record better than 2-2, but Louisville is probably thinking the same thing. The Cardinals are coming off a surprising three-point home loss […]
Brock Purdy Enters Intriguing Conversation After 49ers’ Week 3 Win
The San Francisco 49ers are off to a 3-0 start after beating the Arizona Cardinals in Week 3, 36-20, on Sept. 27 at Levi’s Stadium. Moreover, this start for the Niners has one analyst recognizing starting QB Brock Purdy as arguably one of the best players at his position. Purdy went 15-for-27 on his pass […] The post Brock Purdy Enters Intriguing Conversation After 49ers’ Week 3 Win appeared first on HEAVY.
Deebo Samuel does a lot with a little in Week 3 win against Cardinals
Deebo Samuel's 80-yard TD reception on a day he wasn't credited with a catch highlights efficient performance from aging veteran receiver.
Psycho-cardiovascular interaction network links mental health and heart disease
A new review proposes the psycho-cardiovascular interaction network (PCIN), a framework that links psychological and psychiatric factors with cardiovascular health and disease. The review integrates epidemiological evidence, system-level mechanisms, and molecular signaling pathways to explain how depression, anxiety, chronic stress, and other mental health conditions may contribute to cardiovascular disease (CVD), and vice versa. It focuses on five representative pathways—brain-derived neurotr
Christian McCaffrey goes over 100 total yards vs. Cardinals
Christian McCaffrey keeps chugging along, totaling 116 yards and a score in Week 3 against Arizona.
Cardinals vs. Giants odds: Opening lines for Week 4 matchup
Cardinals open as slight underdogs ahead of matchup with Giants.
San Francisco 49ers rolling but lose players in win vs Cardinals
San Francisco 49ers took care of the Arizona Cardinals but lost a couple players in the process, a familiar storyline.
Arizona Cardinals allow another opening drive TD
The Cardinals have allowed 82-yard touchdowns in two consecutive games.
Arizona Cardinals-San Francisco 49ers 2026 week three discussion thread
Talk about the Arizona Cardinals game against the San Francisco 49ers.
Milwaukee Brewers vs. St. Louis Cardinals score, lineups, TV, updates
The Brewers close out the regular season against the Cardinals at American Family Field on Sunday, Sept. 27 with Jacob Misiorowski on the mound.
49ers vs Cardinals live updates: Score, highlights, analysis
The San Francisco 49ers face the Arizona Cardinals in Week 3. Follow live score updates, highlights, injury news, key plays and instant analysis.
49ers Announce Mike Evans Decision Before Cardinals Game
Mike Evans is expected to be available for the San Francisco 49ers in Week 3, according to Jeremy Fowler of ESPN, with Ian Rapoport confirming the update as well. Mike Evans good to go. https://t.co/FWtPebaDOl — Ian Rapoport (@RapSheet) September 27, 2026 Evans’ Path to Being ClearedEvans left San Francisco’s Week 2 win over the […] The post 49ers Announce Mike Evans Decision Before Cardinals Game appeared first on HEAVY.
NFL Week 3 TV coverage maps
There are 15 games remaining on the NFL schedule in Week 3. Where and when will they air?
Cardinals vs 49ers Prediction, Pick, Odds for NFL Week 3
If you want more Action Network content, be sure to add us as a preferred source on Google. The Arizona Cardinals (1-1) and San Francisco 49ers (2-0) battle in Week
The Best Workout for Lowering Blood Pressure Over 45, According to New Research
A new study suggests that a circuit training routine involving cardio and strength exercises could be most effective for reducing blood pressure.
Cardinals vs. 49ers Week 3 TV Map
Complete list of cities and states the game can be seen on regular TV
How to Watch: Arizona Cardinals at San Francisco 49ers
Everything you need to know about the Arizona Cardinals game against the San Francisco 49ers.
Shedding and raising pounds
Former Wales prop Adam Jones will face one of his greatest challenges when he tackles the Cardiff half-marathon.
Devils beaten 3-1 at Steelers in Challenge Cup
Cardiff Devils remain without a win on the road in the Challenge Cup having been beaten 3-1 at 100% Group A leaders Sheffield Steelers.
Milwaukee Brewers beat the St.Louis Cardinals 3-2
The Milwaukee Brewers beat the. St. Louis Cardinals 3-2 Saturday, September 26, 2026 at American Family Field in Milwaukee, Wisconsin.
A 9-Million-Year-Old Tooth Just Challenged What Scientists Thought They Knew About the Atacama Desert
Scientists were surprised to discover a fossilized tooth from a capybara that lived almost 9 million years ago in what is now northern Chile’s Atacama Desert. Chile’s Atacama Desert is an unlikely place to find traces of capybaras, the world’s largest living rodents, whose lives revolve around water and wetland plants. Yet a fossilized tooth
Dietitian reveals easy ways to eat more whole grains amid new heart health findings
South Carolina-based registered dietitian Lauren Manaker discusses research linking four to six daily servings of whole grains with improvements in several cardiovascular markers and explains simple ways to increase intake.
St. Louis Cardinals vs Milwaukee Brewers Game Discussion Saturday
The St. Louis Cardinals will invade American Family Field again Saturday night for game 2 against the Milwaukee Brewers. Quinn Mathews will put on the pearls for his final start of the season Saturday night for St. Louis while it will be former Cardinals starter Dustin May taking the mound for the Brewers. First pitch […]
This seasonal habit promotes healthy aging and may reduce dementia risk in older people
Aging is inevitable, but there’s increasing evidence that it may be possible to prevent, or at least delay, age-related diseases, including cardiovascular disease and Alzheimer’s.
Furious Fury Blames Eddie Hearn’s Ego For Joshua Collapse
Boxing fans can’t have nice things. Less than two days after Tyson Fury vs. Anthony Joshua was finally announced for Dec. 11 in Cardiff, Wales, the bout is already in jeopardy. This potential cancellation, of course, comes after many years of fans hoping and wishing Fury vs. Joshua would fight. Sadly, the snake-bitten matchup is […]
Bay Area sports calendar, Sept. 26-27
Stanford quarterback Davis Warren and the Cardinal host Georgia Tech on Saturday at 7:30 p.m. (ESPN)
Judge temporarily blocks Boone Health from interfering with PulsePoint Cardiovascular
A Boone County judge granted a temporary restraining order Wednesday in favor of PulsePoint Cardiovascular amid an ongoing legal dispute with Boone Health.
St. Louis Cardinals vs Milwaukee Brewers Game Discussion Friday Night
The St. Louis Cardinals begin the final series of their season Friday night in Milwaukee as Michael McGreevy is the scheduled starter. The Brewers will send Robert Gasser to the mound. First pitch is scheduled for 6:40pm at American Family Field and the game broadcast will be handled by Cardinals.tv.
Google Health 5.09 rolling out: Cardio Load from third-party workouts, more
Following yesterday's announcement, Google Health 5.09 is rolling out with support for the new Health Guardian features on the Pixel Watch.
Judge temporarily blocks Boone Health from interfering with PulsePoint Cardiovascular
A Boone County judge granted a temporary restraining order Wednesday in favor of PulsePoint Cardiovascular amid an ongoing legal dispute with Boone Health.
Pioneer of China NewCo model sued in US over trade secret misuse, double-dealing
A legal feud unfolding in New York is putting a spotlight on the work of a business development veteran who is credited for pioneering one of biopharma’s hottest dealmaking mechanism: the China “NewCo” model. In a lawsuit originally filed in New York state court and recently moved to federal court, China’s Lepu Medical Technology has alleged that biopharma business development consultant Su Zhang, who was hired to help shop its GLP-1 weight-loss candidates to Western partners, engaged in corporate double-dealing and trade secret leaks. According to the complaint, while acting as Lepu’s primary dealmaking liaison for a group of obesity and metabolic disease drug candidates, Zhang was secretly double-dipping as the acting chief business officer for a direct competitor, BrightGene Pharmaceutical. “She never adequately disclosed the role, never sought Lepu’s consent, and never proposed any safeguard,” Lepu alleged in its complaint, which was filed in July after Zhang’s consulting firm, CoDevCo, sought certain transaction-based success fees from its angry customer through an arbitration process in Singapore. Lepu, the parent company of Lepu Biopharma, has asked Zhang to pay back its $500,000 retainer and disgorge all benefits she received during the alleged breaches of fiduciary duty, plus other damages and relief. The company has also requested the court grant injunctions to protect Lepu’s trade secrets. The ill-fated partnership officially kicked off in December 2024, when Lepu tapped CoDevCo as its “exclusive business development mechanism” to identify collaborators for the company’s drug candidates. According to Lepu’s complaint, Zhang personally negotiated and signed the agreement as managing director for CoDevCo, which used her home address. Before the Lepu deal, Zhang made a name following a short stint as the global head of business development for Hengrui Pharmaceuticals. It was during her tenure that Hengrui signed a landmark deal granting exclusive rights for a portfolio of GLP-1 assets to Hercules, which was at that time newly established by a group of private equity and venture capital firms. In addition to the regular upfront and milestone payments, Hengrui also gained an equity stake in Hercules, which later became Kailera Therapeutics. The Hengrui-Hercules deal opened a new paradigm, where a Chinese biopharma company spins off certain early-stage assets to investors for further development through the creation of a new company abroad. The “NewCo” model quickly came into vogue as it allows Western investors to access high-potential assets originating from China at an early stage while giving the Chinese licensors an opportunity to reap long-term benefits through equity stakes in the new firms. The NewCo model proved its value when Kailera staged a record-breaking $625 million IPO on Nasdaq this April, merely two years into the Hengrui deal. Related Kailera CEO 'knew we were in a good spot' before obesity biotech's record-breaking $625M IPO On her LinkedIn page, Zhang described her work at Hengrui as “[b]uilding team and capability from the ground up,” forming NewCo and major pharma partnerships worth billions of dollars. Lepu clearly wanted that kind of track record to help boost its own cardiometabolic portfolio, which includes a range of assets for obesity, Type 2 diabetes, fatty liver disease and muscle preservation during weight loss treatment. “Lepu’s pipeline is very valuable, but only if Lepu could secure the right international partner to expand into the overseas market during the available commercial window,” the company argued in its complaint. The Chinese biotech said it had little knowledge of U.S. laws, customs or business practices in the business development field, and therefore “needed to rely entirely” on the expertise of Zhang and her team as the firm’s first engagement of a U.S.-based BD consultant. “Zhang’s dominating influence on the business development strategy is further evidenced by the fact that she personally controlled the business-development communications on behalf of Lepu with potential partners,” Lepu said in its complaint. After entering the deal, Zhang introduced Lepu to her four associates. According to Lepu’s version of events, all of them were allegedly employed at different time points to perform similar jobs at other Chinese companies that Lepu described as its competitors, while having access to Lepu’s confidential information. As such, Lepu described Zhang’s team as “a roster of individuals whose primary professional loyalty, by virtue of their concurrent full-time employment, ran to Lepu’s competitors.” As well as the specific examples set out in the case, a look at Lepu’s deals over the period suggests Zhang may have been involved in at least one transaction. During their partnership, Lepu, through its subsidiary Shanghai Minwei Biotechnology, also out-licensed its GLP-1/GIP/FGF21 agonist MWN105 to a NewCo called Sidera Bio in the fall of 2025. The deal included an upfront and near-term payment of $35 million, up to $1.01 billion in milestones, and a 9.99% stake in the Danish startup. It seems likely that Zhang facilitated the Minwei deal given that Lepu is on record as having used CoDevCo as its “exclusive business development mechanism.” The big shock for Lepu came in the form of a news article on June 25, 2025. The article, reporting on phase 2 data for BrightGene’s GLP-1/GIP receptor agonist BGM0504, identified Zhang as acting chief business officer of the Lepu rival. Blindsided by her association with BrightGene, Lepu confronted Zhang in July 2025. “Lepu was given assurances that there was nothing to be concerned about and told that Zhang would explain the matter to Lepu,” Lepu alleged in its complaint. “Zhang never did.” Lepu claimed that Zhang had the motive and opportunity to steer potential prospective partners toward BrightGene or other competitors. Later, in February 2026, one of Zhang’s associates joined BrightGene as the vice president for global business development, according to the complaint. Around the same time, Lepu sent written demand letters asking Zhang to account for her BrightGene role, identify what confidential data were shared with the rival firm, and provide any conflict-of-interest or firewall policies during the engagement. According to Lepu, neither CoDevCo nor Zhang answered the questions in their responses. Related Novo vs. KBP: How a $1.3B deal turned into a fraud accusation and an international legal fight In a motion to dismiss filed with the U.S. District Court in the Eastern District of New York on Sept. 4, Zhang’s legal team argued that Lepu’s agreement was signed with CoDevCo, and that an employee of the contractor does not owe fiduciary duties to the client. In its complaint, Lepu said: “That CoDevCo was the contracting entity does not insulate Zhang from personal liability for duties she personally undertook and personally breached.” Taking the argument one step further, the defending party argued that the consulting agreement “does not create a fiduciary relationship even between CoDevCo and Lepu; instead, it identifies CoDevCo as an independent contractor retained to market Lepu’s business to potential western partners.” Although CoDevCo was Lepu’s exclusive business-development contractor, there were no terms stipulating that the consulting firm should serve only Lepu, Zhang’s lawyer noted. As to Lepu’s claims that Zhang misappropriated trade secrets, the defendant argued that Lepu authorized the use of the information so Zhang’s team could perform their service per the agreement. In a rebuttal filed on Sept. 11, Lepu’s lawyer set out why they believe the Chinese biotech satisfied New York law’s misappropriation definition by alleging that the defendant used a trade secret “in breach of a duty or through improper means.” As an alternative to dismissing the suit, the defendant suggested the action should be stayed pending outcomes from the arbitration of a separate case in Singapore. While NewCo pioneer Zhang is defending her business arrangements, momentum behind the NewCo trend has continued unabated into 2026. Through August, Chinese biotech assets have spurred 15 NewCo deals this year, according to local trade publication PharmaDJ.
49ers injury report: Mike Evans sits out again Thursday
See which 49ers players did not practice or were limited in practice on Thursday.
3 Reasons to Watch the Cardinals’ Final Series
For the fourth straight season, the St. Louis Cardinals will not make the playoffs. For the third time in those four seasons, they will have a losing record. While the team has made major progress this season, it is still disappointing given the organization's rich tradition of winning. As a result, it's easy for members …
Brewers Roll Out Expected Postseason Rotation vs. Cardinals
Rising Milwaukee Brewers southpaw Robert Gasser looks to stay hot while Dustin May fights for his role.
Cardinal Health (CAH) Stock Looks About Right At Today’s Price
Cardinal Health has been a powerful performer over the past several years. The question now is whether the current share price lines up with what the business is earning. With the stock pulling back slightly in the short term after a strong multi year run, investors are increasingly focused on what its earnings actually justify. Cardinal Health has returned about 378.2% over the past 5 years, which puts real pressure on the current valuation story to be supported by the earnings profile. The...
Semaglutide is improving the heart health of millions—but how? Experts are stumped
“Our analyses could not fully ascribe the effects of semaglutide on cardiovascular disease to known risk factors with any certainty,” one researcher said after exploring years of data. "These results suggest that semaglutide should be considered as a cardiovascular disease reduction drug and not just as a weight loss drug,"
49ers Get Concerning Injury News Ahead of Cardinals Game
Ahead of Sunday’s matchup with the Arizona Cardinals, the San Francisco 49ers kicked off preparations Wednesday, and their initial Week 3 participation report showed a busy list of absences. 49ers Lose Another Defensive Tackle to IR San Francisco placed defensive tackle C.J. West on injured reserve Wednesday with a knee injury, the ninth player the […] The post 49ers Get Concerning Injury News Ahead of Cardinals Game appeared first on HEAVY.
Walking This Many Steps Extra Each Day Could Reduce Heart Disease Risk
In TODAY.com’s Expert Tip of the Day, a cardiologist explains why you don’t need to aim for 10,000 steps a day to have a healthier heart and her advice to patients.
Admiral to cut 500 UK jobs in £100m cost drive
The Cardiff-based insurer says the cuts are about efficiency, not AI. It is the latest in a run of UK insurers shrinking headcount as motor margins tighten
St. Louis Cardinals vs Pittsburgh Pirates Game Discussion Wednesday
The St. Louis Cardinals will do battle with the Bucs again at PNC Park Wednesday night. Matthew Liberatore is the scheduled starter for the Cardinals Wednesday night while the Pirates have announced RHP Lake Bachar as their starter. First pitch is scheduled for 5:40pm central time and the game broadcast will be available via Cardinals.tv.
Early childhood BMI trajectories predict later cardiometabolic health risks
Childhood obesity predicts later cardiometabolic disease, but single-time weight measures may miss dynamic growth information.
Draft analyst Jeremiah: Marvin Harrison Jr. is unrecognizable with Cardinals
Marvin Harrison Jr's rapid decline since the NFL Draft is puzzling to evaluators.
Alec Burleson’s Gold Glove Case
When you think of Alec Burleson, you think of his power. His 23 home runs and 111 RBI have helped the St. Louis Cardinals exceed expectations this season. In fact, he currently leads MLB in RBI. Burleson's offensive resume already includes a Silver Slugger, earning it last year as a utility player. He is a …
New schizophrenia treatments, AI in mental health among topics at inaugural symposium in Roanoke
The two-day gathering on precision therapeutics will be held at the Fralin Biomedical Research Institute at VTC.
What links smoking, body fat, mental health, genes, and heart risk? Inflammation may be part of the answer
In a large UK Biobank study, higher levels of the chronic inflammation marker GlycA were associated with smaller heart chambers, thicker heart walls, impaired diastolic function, reduced stroke volume, and a 43% higher risk of major adverse cardiovascular events in the highest versus lowest GlycA group. Genetic susceptibility also modified the associations between environmental exposures, inflammation, and cardiovascular risk, while inflammatory proteins in the IL-1, TNF, and IL-6 pathways statistically mediated several of these associations.
SMU's Kevin Jennings Praises 'Good Response' After Louisville Nightmare
The Mustangs have moved on from their loss to the Cardinals, with Missouri State up next.
St. Louis Cardinals vs Pittsburgh Pirates Game Discussion Tuesday
Just 6 games to go for the St. Louis Cardinals this season. Tuesday night, it’s the beginning of a 3-game series against the Pittsburgh Pirates. Andre Pallante will get the start for the Cardinals while the Pirates will give the ball RHP Jared Jones. First pitch at PNC Park in Pittsburgh is scheduled for 5:40pm […]
Arizona Cardinals fall in new 2026 power rankings
Arizona Cardinals fall in most new power rankings.
San Francisco 49ers schedule, stats through 2 games
A look at the 49ers, whom the Cardinals face in Week 3, and what they have done so far in their 2-0 start.
New translational research awards aim to redefine health for women
DALLAS, September 22, 2026 — Despite decades of progress in cardiovascular science, women continue to face significant gaps in research, diagnosis and treatment, according to a report published by the American Heart Association and the McKinsey Health...
The Cardinals Season is Over, But the Future is Bright
The 2026 schedule hasn’t yet concluded, but the Cardinals’ playoff hopes are officially extinguished. From JJ’s debut and Burley’s monstrous blast that set the tone for the season on opening day, to a group of SFA baseball players taking their shirts off and swinging them over their heads. Jordan Walker reintroducing himself to the baseball […]
Cardiff pain must lead to progress for Charlton
Charlton Athletic fan Paul Sullivan hopes the club can use the extended international break wisely
Is 50 the new 60?
Subscribe TL;DR: Younger generations are showing signs of worse health compared to earlier-born cohorts at the same age This backward “drift” is showing up both in mortality risk and chronic disease Worsening trends in obesity and diabetes are the most consistent signals Taking the long view, we’ve made astonishing gains in health and life expectancy in the last century. Global average life expectancy has more than doubled from 32 years in 1900 to 73 years in 2024. (But don’t forget, there were still old people when life expectancy was 32). As people lived longer, they also generally lived healthier along the way. It turns out that avoiding things that can kill you early, like malnutrition and lots of childhood infections, also keeps you healthier later in life. In a classic 2004 paper, Finch and Crimmins proposed that cohorts of children who benefited from fewer early life infections had less lifetime exposure to inflammation and cardiovascular disease later in life, accelerating mortality improvements at older ages. Poor nutrition in the womb has also been linked to a higher risk of later chronic disease. The upshot is that improvements in childhood health can pay dividends many decades later. The combination of better living conditions (nutrition, sanitation) and medical advances (antibiotics, vaccines, blood pressure meds, etc) meant that people’s healthy lifespan generally expanded, even as they lived longer. Aging researchers call this best-case scenario “compression of morbidity”—meaning we delay the onset of disease and disability even faster than the years of life we are adding. During my 20+ year research career, we could generally bank on the idea that younger generations would not only live longer but also keep getting healthier along the way. “60 is the new 50” as they say… Enter “Generational Health Drift” Sadly, this expectation of steady progress may be changing. You’ve probably heard that US life expectancy gains have slowed to a crawl in the past couple of decades. Mortality improvements are also slowing (though less dramatically) in many other high-income countries (you can read more about that in a review paper I wrote here). Mortality is a very blunt health measure, but it is often a good barometer for the broader population health trends happening underneath. And we are now seeing that younger generations may be in worse health at similar ages compared to earlier born cohorts. My collaborator Prof. George Ploubidis at University College London coined this worsening health in more recently born cohorts “generational health drift.” “Generational health drift” is bad news on multiple fronts. Most obviously, we don’t want our health progress to go backward. But the timing is also bad, since our populations are aging. In demographic terms, “population aging” means that the proportion of the population at older ages (i.e >65 years) is increasing. Fun demography fact: Current population aging is not due to the recent declines in the birth rates making the news, but declines in fertility decades ago, after the “baby boom.” As baby boomers reach older ages, the smaller cohorts behind them mean the percentage of older adults will increase. For example, the share of the population age 65 and older in the US increased from 12.4% in 2004 to 18.0% in 2024. This story of population aging was written long ago. Many worry that population aging will put pressure on health care and pension systems. But if people reach older ages in better health than in years past, those fiscal pressures would be less dire than projected. Healthy older people can also continue to contribute to society in many valuable ways, including paid work, caregiving, community service….even high political office 🤷. On the flip side, if younger generations reach retirement age in worse health and with more disabling conditions, this could magnify the societal challenge of population aging. Evidence for worsening generational health A recent paper that I LOVED in the Proceedings of the National Academy of Sciences by Dr. Leah Abrams and colleagues examined which birth cohorts (aka generations) were behind worsening US mortality. Behold the Lexis diagram (cue swooning demographers). Calendar time is on the x-axis, age on the y-axis. Birth cohorts can be followed over time as they age on the diagonal lines moving up and to the right. This figure plots the year-on-year % change in all-cause mortality at a given age. Green shading indicates mortality improvements over time, white is stagnation, and gray shading indicates worsening mortality. Following the diagonal line for those born in 1950, you can see a noticeable shift from green to gray that follows this cohort for most of their lives. This gray shading shows generally worsening mortality for the 1950 to 1959 birth cohorts compared to their predecessors across all ages. Concerningly for my GenX and elder millennial peeps, there was also a deterioration in mortality for birth cohorts born in the 1970s and 1980s, visible as dark gray areas at ages 30 to 45 during the 2010s. While some of these mortality changes reflect specific shocks such as the opioid epidemic, most deaths still occur from major causes of death such as cardiovascular disease and cancer. For cancer, the gray in the top left corner of the figure below reflects the legacies of smoking for older cohorts, followed by a period of green with improvements in cancer mortality as smoking rates declined. But the white/gray shading in the bottom right corner highlights a stagnation and reversal of the cancer trends, with cohorts born around 1970 to 1985 experiencing worsening cancer mortality. This deterioration was most noticeable for colon cancer mortality, possibly linked to obesity or dietary factors. Not just dying more, but less healthy along the way. A recent paper by Dr. Laura Gimeno of University College London (of which I am a co-author), found evidence that more recently born cohorts in Great Britain have stagnating or worsening health. A stylized picture of what“generational health drift” might look like: The review paper found: Rates of childhood overweight and obesity were highest among Gen Z. Rates of diabetes in the 40s almost doubled from 3.1% among the Baby Boomers to 5.9% in Generation X. Gen Z reported higher rates of poor mental health in adolescence compared to earlier-born groups. These UK results are consistent with studies showing worsening health across generations in the US as well. A 2021 US study found that more recently born cohorts had worse biological markers (like blood pressure and blood sugar) than earlier generations at the same age. A separate 2022 study of Americans aged 50 and over found that more recently born generations had a higher number of chronic diseases, with younger age of disease onset. A 2024 Lancet paper found that in the US, women born in 1945 had 33% obesity prevalence at age 50, rising to 48.2% for women born in 1970 turning 50. So what’s going on, and can we turn it around? We don’t have a definitive answer for what’s causing the deteriorating health of younger cohorts, but circumstantial evidence points to worsening trends in obesity and diabetes in both the US and UK. Remember that cohort trends reflect lagged effects of early environments, and younger generations have faced both earlier onset and more severe obesity across their lifetimes. Despite these very concerning trends, the future is not set in stone. We’ve reversed poor generational health trends before: drops in smoking are a major reason cancer and heart disease deaths fell so dramatically in recent decades. GLP-1 drugs may finally turn the tide against rising rates of obesity and diabetes, though it is still early days. But things could also get worse…for example from a return to higher levels of childhood infectious diseases that can have a lasting impact on health. See for example: [ ](https://jenndowd.substack.com/p/dont-you-forget-about-measles-the) [ Don’t You Forget About Me(asles): The Virus That Erases Immune Memory ](https://jenndowd.substack.com/p/dont-you-forget-about-measles-the) Jenn Dowd, PhD · March 24, 2025 [ Read full story ](https://jenndowd.substack.com/p/dont-you-forget-about-measles-the) Even as an optimist, emerging data on the “generational health drift” has my full attention. For most of my research career, we took it for granted that each generation would be healthier than the last. But if present trends continue, **50 could be the new 60….**and Gen Z celebrities will soon look older than Paul Rudd :). Stay well, Jenn Share the Health! If you found this post useful, please share it with a friend. Share
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(Feature Impact) Driven by rising rates of obesity, diabetes, high blood pressure and other risk factors, cardiovascular disease has surpassed cancer as the leading cause of death among Hispanic adults in the United States. googletag.cmd.push(function() { googletag.display('fixed-big-ad-top-asset'); }); Hispanic people represent nearly 1 in 5 of the U.S. population and are the nation’s largest ethnic minority group, yet many continue to face barriers to achieving heart health and accessing high-quality healthcare. A new scientific statement published in the American Heart Association’s flagship journal, “Circulation,” revealed how social, economic, cultural and environmental factors contribute to persistent disparities in cardiovascular health, calling for culturally tailored prevention strategies, equitable access to care and greater representation of Hispanic populations in cardiovascular research.“Hispanic populations in the U.S. are incredibly diverse even within their own communities with differences in genetic ancestry, language, cultural traditions and social experiences that can significantly influence cardiovascular health,” said Johanna Contreras, M.D., M.Sc., FAHA, director of the Division of Heart Failure and medical director of the Hispanic Heart Center within the Mount Sinai Health System. “Yet Hispanic people remain underrepresented overall in the research that guides prevention and treatment strategies… Without better representation and more detailed data, we risk overlooking important differences that can help us improve care and save lives.”Hispanic Cardiovascular Health by the NumbersCardiovascular risk factors – obesity (nearly 46%), type 2 diabetes (15.5%) and high blood pressure (approximately 44%) – are prevalent among Hispanic adults and often emerge at younger ages and occur more frequently among Hispanic adults compared with white adults.According to the report, only about 1 in 5 Hispanic adults achieves ideal cardiovascular health as defined by the American Heart Association’s original Life’s Simple 7 metrics. Updated analyses using the Life’s Essential 8 framework demonstrated persistent disparities for heart and brain health, as well as suboptimal dietary quality, sleep patterns and levels of physical activity.Social and Economic Barriers MatterBiology alone does not explain cardiovascular health disparities. The environments where people live, work and age, along with social and economic challenges, impact heart health. In fact, approximately 17% of Hispanics live below the federal poverty threshold, compared with 8.2% of white adults. googletag.cmd.push(function() { googletag.display('fixed-big-ad-middle-asset'); }); “Many Hispanic adults face obstacles that extend far beyond the doctor’s office,” Contreras said. “Limited health insurance coverage, language differences, food insecurity, environmental exposures and concerns related to immigration status can make it more difficult to prevent disease, manage chronic conditions and receive timely treatment.”Contreras emphasized the cultural values and practices of Hispanic people also influence how they perceive their health and healthcare options.“Family plays a central role in many Hispanic communities and can be an extraordinary source of strength, support and resilience,” Contreras said. “At the same time, family members are often called upon to translate medical information, navigate health systems and help make healthcare decisions for loved ones. Those responsibilities can shape how health information is understood and acted upon.”An Action Plan for Improving Hispanic HealthThere are practical opportunities to achieve equitable cardiovascular health and reduce disparities through community engagement, culturally responsive care, inclusive research and policies that address the underlying drivers of health.“Reducing cardiovascular disease among Hispanic populations demands action at every level,” Contreras said, “from improving access to culturally responsive care and expanding research participation to addressing the social and environmental conditions that shape health.”By addressing both medical risk factors and the social conditions that shape health, experts believe there is an important opportunity to reduce disparities and help more people live longer, healthier lives. Learn more at Heart.org.Photo courtesy of Shutterstock googletag.cmd.push(function() { googletag.display('fixed-big-ad-bottom-asset'); });