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Marshfield Clinic receives nearly $580,000 mental health grant
Marshfield Clinic has received a three-year, nearly $580,000 federal grant to expand mental health education and access across 17 counties in central, northern and western Wisconsin.
Celebrating Excellence in Student Health: District Nurses Earn National Certification - Pine Bush Central School District
We are proud to celebrate two of our very own school nurses, Kathleen Chamberlain and Linda Loennecker, our nursing department chair, for achieving national certification through the National Board for Certification of School Nurses (NBCSN)! Achieving NBCSN certification is a major milestone in school nursing. The rigorous examination tests advanced clinical expertise, specialized knowledge, and … Continue reading "Celebrating Excellence in Student Health: District Nurses Earn National Certification"
Michael Lemma: The Science Behind Fenbendazole and Ivermectin Cancer Claims
Michael Lemma: The Science Behind Fenbendazole and Ivermectin Cancer Claims / cancer, cancer treatment, Celebrity Testimonials, clinical evidence, Drug
UFC AND CLEVELAND CLINIC RENEW LONGSTANDING PARTNERSHIP
UFC To Provide $1 Million Contribution To Fund Professional Athletes Brain Health Study Through 2030 WWE Joins Study; Zuffa Boxing Athletes Now Eligible To Participate
Verana Health and Bitfount Collaborate to Simplify Prescreening for Ophthalmic Clinical Trials
/PRNewswire/ -- Verana Health®, a digital health company dedicated to revolutionizing patient care and clinical research through real-world data (RWD), has...
FDA-approved epilepsy drug may help reverse osteoarthritis damage
Researchers at Yale have identified a promising new approach to osteoarthritis that could do more than simply ease pain. The epilepsy drug lacosamide appears to block a protein involved in both pain signaling and cartilage destruction, helping damaged joints shift back toward repair in preclinical studies.
West Baton Rouge Parish Health Clinic hosts free health screening fair
West Baton Rouge Parish Health Clinic hosts free health screening fair
The Math Singularity Is Here, and Science May Be Next
OpenAI has released an extraordinary body of mathematical work produced by an unreleased frontier model: 722 manuscripts spanning 372 research families across fields including number theory, complexity theory, and mathematical physics. Each result required, on average, the equivalent of roughly three hours of ChatGPT Pro reasoning. A New Era of Discovery We may be witnessing the beginnings of a “math singularity”: a point at which machine-generated discovery accelerates beyond humanity’s ability to independently reproduce, verify, or fully absorb it. If frontier models can generate hundreds of meaningful results in the time it takes a human researcher to investigate one, the constraint will no longer be producing new mathematics. It will be our capacity to validate, interpret, and integrate it. This does not make mathematicians obsolete. It changes their role. They may increasingly serve as guides, critics, and meaning-makers. Increasingly, they will decide which questions matter, determining which results can be trusted, and explaining why they are important. Mathematical insight may become abundant, while human judgment becomes more valuable than ever. Mathematics May Be Only the Beginning Every scientific discipline could eventually experience a similar acceleration. AI systems could generate and test hypotheses, connect findings across specialized fields, and explore possibilities at a scale no human research community could match. In medicine, imagine models identifying overlooked disease mechanisms, designing drugs and clinical trials, personalizing treatments, or discovering cures in months rather than decades. In materials science, AI could help create better batteries and cleaner industrial processes. In climate science, it could accelerate advances in energy, forecasting, and carbon removal. In biology, it could uncover relationships hidden across enormous genomic and molecular datasets. The result would not simply be faster research. It could expand the frontier of what is scientifically possible. The New Bottleneck Scientific discovery, however, is not the same as scientific progress. A medical breakthrough must still survive laboratory testing, clinical trials, regulatory scrutiny, manufacturing constraints, and real-world deployment. As machine-generated ideas multiply, the bottleneck may shift from producing breakthroughs to validating them safely and translating them into practice. We may soon have more hypotheses than laboratories can test, more drugs than clinical trials can evaluate, and more mathematical results than experts can review. That imbalance will require better systems for automated verification, reproducible research, prioritization, peer review, and collaboration between AI and domain experts. The importance of OpenAI’s work is not merely the number of manuscripts produced. It offers a glimpse of a world in which intelligence can explore thousands of intellectual paths in parallel. If ideas cease to be scarce, humanity’s defining challenge will be deciding which are true, which matter, and how to turn them into progress. The math singularity is not the end of human inquiry. It is the beginning of a new kind—one in which machines expand the frontier of knowledge and humans decide where it should lead. Subscribe Share Leave a comment
Philips Oral Healthcare establishes Global Clinical Advisory Board to help shape the future of oral care through scientific and clinical insight
Philips Sonicare establishes a Global Clinical Advisory Board of dental experts to provide scientific, clinical and strategic guidance.
Should Diseases Be Renamed When Science Advances?
Changes in scientific understanding are prompting renewed scrutiny of disease names and their effects on how patients, clinicians, and researchers view conditions.
IQVIA Launches IQVIA Life Science Models to Help Life Sciences Companies Predict Clinical Trial Outcomes
RESEARCH TRIANGLE PARK, N.C.--(BUSINESS WIRE)--IQVIA (NYSE:IQV), a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries, today at TechIQ 2026 introduced IQVIA Life Science ModelsTM to help predict clinica
Mayo Clinic Health System doctor urges women to discuss family breast cancer history
“It affects your mom, your sister, your aunt and sometimes, unfortunately, yourself."
IQVIA Launches IQVIA Life Science Models to Help Life Sciences Companies Predict Clinical Trial Outcomes
RESEARCH TRIANGLE PARK, N.C.--(BUSINESS WIRE)--Oct 7, 2026--
On the front lines: How rural clinics are confronting measles challenge
There were 108 reported cases of measles in the state as of Oct. 3, according to Gov. Kathy Hochul.
Baptist Health, Seale Harris Clinic Named Lead Tenants at Riverwalk Health Center
Baptist Health and Seale Harris Clinic have signed leases to become lead tenants at the planned Riverwalk Health & Wellness Center in Hoover, with the facility
IQVIA Launches IQVIA Life Science Models to Help Life Sciences Companies Predict Clinical Trial Outcomes
RESEARCH TRIANGLE PARK, N.C.--(BUSINESS WIRE)--Oct 7, 2026--
IQVIA Launches IQVIA Life Science Models to Help Life Sciences Companies Predict Clinical Trial Outcomes
RESEARCH TRIANGLE PARK, N.C., October 07, 2026--IQVIA (NYSE:IQV), a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries, today at TechIQ 2026 introduced IQVIA Life Science ModelsTM to help predict clinical trial outcomes.
Science on Target: Q3 Research We Conduct
The Target ALS Global Natural History Study (GNHS) is entering a new phase of discovery. As the only international, longitudinal study generating deeply characterized clinical, genomic, and biofluid data to accelerate ALS biomarker discovery and therapeutic development, the GNHS is now beginning to deliver large scale datasets and resources needed to support new insights into […]
Science on Target: Q3 Research We Fund
$2.4 million Invested in Biomarker Innovation ALS is a heterogeneous disease with distinct subpopulations of cases clustering together based on common underlying biology and with distinct differences in the clinical time course and manifestation of disease. Biomarkers are therefore critical for enabling precision medicine to deliver the right therapy to the right individual at the […]
Community Clinic awarded $3 million federal grant
Springdale-based healthcare provider Community Clinic will receive $3 million from the Health Resources and Services Administration to expand rural substance use disorder prevention, treatment and recovery services in rural areas...
Anthony Rizzo supports young athletes, cheers on White Sox and prepares for Chicago Marathon
Former Cubs star Anthony Rizzo spent Wednesday inspiring young athletes in Chicago, sharing lessons from sports while supporting a youth clinic before heading to a White Sox playoff game.
Why muscle health should be a bigger part of clinical nutrition
Experts call for greater attention to muscle health across aging, illness and weight loss.
Alpharus Health Expands Access to Mental Health Services Across Illinois
Chicago, IL, Oct. 07, 2026 (GLOBE NEWSWIRE) -- Alpharus Health is expanding access to mental health care across Illinois by bringing comprehensive behavioral health services to 11 of its 13 community outpatient clinics. Alpharus Health now offers outpatient mental health treatment services in Aurora, Bloomington, Carbondale, Chicago, Downers Grove, Gurnee, Jacksonville, Joliet, Peoria, Springfield, and Swansea. Alpharus Health also offers virtual mental health treatment for all Illinois resident
Nexira spotlights menstrual health ingredient BloomEase and ViNitrox vascular data at SupplySide Global
New clinical findings show ViNitrox improves Flow-Mediated Dilation by 41% versus placebo — while Nexira enters the longevity segment with NU4LIFE and VinOgrape Plus targeting mitochondrial and microbiome health
Oklahoma Children’s OU Health to open northwest OKC clinic
Oklahoma Children’s OU Health will open a northwest Oklahoma City clinic Oct. 22 offering pediatric neurology and endocrinology care.
University of Lynchburg to launch online Master of Science in Counseling programs
In January of 2027, the University will launch the online Master of Science in Clinical Mental Health Counseling and Master of Science in School Counseling programs.
Why you’re voting on how medical clinics spend their money
California’s Prop 44 limits how medical clinics spend on administrative expenses. A healthcare union argues some are shortchanging patient services.
CVS Health® reminds New Yorkers that MMR vaccines are available statewide amid measles outbreak
Eligible patients can receive MMR vaccinations at more than 530 CVS Pharmacy® locations across New York and at MinuteClinic® locations WOONSOCKET, R.I., Oct....
Gastro Health and House Rx Announce Launch of Medically Integrated Dispensing
/PRNewswire/ -- House Rx, the leader in medically integrated dispensing solutions for specialty care clinics, and Gastro Health, one of the nation's largest...
AMO Pharma in Collaboration with Population Health Research Institute (PHRI) and Venca Research Inc. Announces FDA Advice on Potential Phase 3 Development Path for AMO-02 in Treatment of Arrhythmogenic Cardiomyopathy (ACM)
/PRNewswire/ -- AMO Pharma Limited ("AMO Pharma"), a privately held clinical-stage specialty biopharmaceutical company focusing on rare genetic disorders with...
The same union supporting a billionaire tax wants voters to limit clinic spending. Here’s what to know about Prop. 44
Prop. 44 would require clinics to spend more money on patient care, but clinics say the measure will bankrupt them.
GLP-1 Drugs? Surgery? WHO Issues Guidelines For Obesity In Children
The World Health Organization (WHO) released its first-ever guidelines to address how clinicians should manage obesity in children and adolescents, which
More health claim denials will hurt patients and clinics
A measurable change is seen in the financial system supporting care. Data shows claim reductions and denials have increased by more than 30%.
Baumgartner Takes Major Step Towards Leipzig Comeback
After 128 days sidelined by surgery, the Austrian playmaker rejoins team training to rescue a struggling attack missing his clinical finishing and veteran leadership from midfield.
Pilot Project Aids Cancer Survivors in Achieving Healthy Weight and Reducing Recurrent Risk
New program will help patients improve fitness and manage weight after cancer treatment
PTSD, Health-Related Social Needs Together Increase Cognitive Risks Significantly in Veterans
A recent study asked a question critically important to VHA clinicians: Are post-traumatic stress disorder (PTSD) and health-related social needs (HRSNs) associated with incident mild cognitive impairment, Alzheimer’s disease and Alzheimer’s disease-related dementias among U.S. veterans?
Stressed out by politics? You’re not alone. Political stress is rising, therapists say
After several years as a clinician helping couples and individuals navigate the struggles of daily life, therapist Amity Heyborne began noticing a new source of distress among her clients: political polarization.
Aspirus Health to offer flu vaccinations at multiple clinics starting this week
The organization says it has seen an uptick in people wanting to be vaccinated over the past few years.
New Clinical Guideline Helps Keep Women 'Optimized for the Fight'
The Department of Veterans Affairs and War Department have jointly released a clinical practice guideline to help clinicians provide improved care for women experiencing perimenopause and menopause.
Spooky stroll, outdoor movie night: 6 events to attend in New Caney, Porter this weekend, Oct. 9-11
Explore weekend events in New Caney and Porter from Oct. 9-11, including a pet vaccine clinic, fall festivals, a pop-up market and an outdoor movie night.
Ochsner uses AI to widen clinical trial screening
The health system reports 41% greater screening capacity, 3.6 times as many patients followed for future eligibility and approximately 75% less manual screening work. The vice chief scientific officer tells the tale.
UAMS Receives Grant to Provide Telehealth Nutrition Services, Remote Monitoring in Clinics in Batesville, El Dorado
The University of Arkansas for Medical Sciences (UAMS) will integrate telehealth nutrition services and remote patient monitoring at two of its clinics to help patients better manage their diabetes and chronic health conditions.
What are hospital longevity programs, and what can they tell you about your health?
What can hospital longevity clinics can tell you about your health? STAT's Sarah Todd went to one to find out.
Childhood obesity less common under new health-based definition
A new global definition of clinical obesity classifies far fewer children as obese than widely used body mass index (BMI) thresholds, according to a large international study. The findings could lead ...
IceCure Expands ProSense® ChoICE Study for Low-Risk Breast Cancer adding Legacy Health in Portland, OR as U.S. Clinical Site
/PRNewswire/ -- IceCure Medical Ltd. (NASDAQ: ICCM) ("IceCure," "IceCure Medical" or the "Company"), developer of minimally-invasive cryoablation technology...
Cigna Healthcare Introduces Health Sense To Connect Guidance, Benefits and Clinical Support Around Each Person, Improving Affordability and Outcomes
/PRNewswire/ -- Cigna Healthcare, the health benefits division of The Cigna Group (NYSE: CI), today introduced Health Sense℠, a personalized customer and...
Sanford Health Fargo offering flu shots at clinics, hosting vaccine events including ‘Boo to the Flu’
Sanford Health Fargo is now offering flu vaccinations to patients 6 months and older at all Fargo metro area primary care clinics.
Industry Insights: Q&A with Estée Lauder’s SVP of Global Clinical, Consumer Sciences on One-of-a-Kind Complexion Research
“A shade can be technically close to a person’s skin tone and still not look completely natural in every situation.”
Health Sense by Cigna Healthcare: How it works, AI, clinical support, and availability
Health Sense connects relevant data, context and clinical expertise to help Cigna Healthcare teams deliver more personalized, continuous support – so people can make informed decisions and act sooner. A phased rollout for eligible customers with oncology and cardiometabolic health needs will begin in early 2027.
Myakka City studies whether it needs a health clinic at its elementary school
MCR Health and Results 1st have received a grant from the Bishop-Parker Foundation to assess the need for a clinic.
Can you live longer for $5,500? Longevity clinics are the buzzy new trend at nonprofit hospitals
Longevity clinics promise personalized health advice and cutting-edge tests. Now major hospitals are entering the business, at costs reaching $45,000 a year.
8 Fermented Foods To Add to Your Diet
Fermented foods like pickles and kimchi can help keep your gut health. An expert shares which foods are worth adding to your meals.
Little Rock board votes to fund construction of city employees’ health clinic
The Little Rock Board of Directors on Monday agreed to pay for the construction of a health clinic for city employees.
Portage Co. Health and Human Services announces free flu shot clinic for kids
Portage Co. Health and Human Services announces free flu shot clinic for kids
2 Years After Historic Union Vote, Bicycle Health Clinicians Still Lack a Contract
Nearly two years after voting to unionize, Bicycle Health clinicians have yet to reach a contract agreement, representatives of the Union of American
Did New Science Board Just Shift BioCryst's (BCRX) Investment Narrative?
BioCryst Pharmaceuticals recently formed a seven-member Scientific Advisory Board made up of experienced rare disease and drug development leaders to guide its research, clinical plans and regulatory approach. The depth of this board, spanning big pharma R&D, AI driven drug discovery and rare disease commercialization, directly targets BioCryst’s execution risk as it builds a broader pipeline beyond its current portfolio. We will now examine how BioCryst Pharmaceuticals’ investment narrative...
NYC Health + Hospitals/Woodhull Marks Simulation Week with Hospital-Wide Training to Advance Patient Safety and Clinical Readiness
NYC Health + Hospitals/Woodhull celebrated Simulation Week on September 25 with an interdisciplinary simulation event designed to strengthen
Essentia Health-Virginia Clinic welcomes Emily Reed to practice family medicine
Emily Reed, an advanced practice registered nurse and certified nurse practitioner specializing in family medicine, is thrilled to join the Essentia Health-Virginia Clinic.
ASU designs a statewide pipeline for Arizona's anesthesia workforce
Every surgery, C-section, trauma case and cancer operation in Arizona depends on a clinician administering anesthesia and keeping the patient safe while the surgeon works. The state needs more of these clinicians.As of September, the Arizona State Board of Nursing lists 1,759 certified registered nurse anesthetists, or CRNAs, in the state. In 2023, Arizona was short 732 nurse anesthetists, and the shortage is projected to reach 868 by 2033.
Davids Fights Washington Healthcare Cuts with Plan to Lower Costs, Protect Kansas Hospitals
WASHINGTON, D.C. — Today, U.S. Representative Sharice Davids (KS-03) introduced a comprehensive package of healthcare legislation that directly counters Washington’s recent healthcare rollbacks, which are increasing monthly costs and closing rural hospitals. Davids’ efforts would protect Kansas families from rising medical costs, block new federal red tape, and keep local hospitals and health clinics open.
Livelong Women’s Health Summit Builds Momentum for 2027 Expansion
The Livelong Women's Health Summit brought together consumers, clinicians, researchers, and health experts for conversations spanning menopause, strength and performance, brain health, nutrition, hormones, and the science of aging. The Health & Fitness Association (HFA) served as a sponsor for the event.
Science Corp. Announces Long-Term (36 Months) Results of PRIMA BCI Clinical Trial Showing Durable Vision Restoration in Blind Patients Suffering from Geographic Atrophy
Science Corporation, the neural engineering and brain-computer interface (BCI) company, today announced long-term (36 months) followup data from its pivotal ...
Should Aging Be Called a Disease? Scientists Are Rethinking What It Means to Grow Older
What if the next big target in medicine is getting older itself? Researchers are taking that possibility seriously, with new tools, new clinics, and growing FDA attention. Instead of waiting for diabe...
2026 Outstanding Women in Business
The 18th annual Outstanding Women in Business awards recognize a dozen well-accomplished professionals from across the region and in many industries who go above and beyond. The committee selected the winners from more than 80 nominations, all of whom were worthy. The criteria evaluated each nominee’s professional achievements, community impact, ability to break the glass ceiling and mentorship of other professionals, particularly women. In addition to profiling these women in the following pages, the Worcester Business Journal will celebrate this year’s Outstanding Women in Business at a special luncheon on Oct. 28 at the College of the Holy Cross. To join the celebration of these exceptional women, visit WBJournal.com and register. – Mark Conti, editor This Year’s Judges Worcester Business Journal considered 54 Central Massachusetts professionals for the 2026 Outstanding Women in Business awards, based on 83 nominations. These nominees were independently evaluated by two volunteer judges, who scored each on their professional achievements, community contribution and mentorship of young professionals. Samantha P. McDonald is a partner at Bowditch. She is an experienced, client-focused real estate lawyer, concentrating on business and real estate property law. She has been recognized as a WBJ Power 100 in the Class of 2026 and a “Top Women of Law” in Massachusetts Lawyers Weekly. Dr. Kavita Babu is chief medical officer and vice president of medical affairs at Heywood Healthcare, where she provides strategic and clinical leadership to advance high-quality, patient-centered care across the organization. She is also a member of the WBJ Outstanding Women in Business Class of 2025.
Flathead City-County Health Department to hold annual flu clinic
The Flathead City-County Health Department will hold its annual flu clinic Wednesday, Oct. 7, at the Flathead County Fairgrounds Expo Building.The clinic will r
Tracking health misinformation helps pediatricians provide targeted patient education
Pediatric clinicians can learn useful information by tracking the health misinformation that their patients encounter, according to research presented during the American Academy of Pediatrics 2026 National Conference & Exhibition Oct. 2-6, 2026, at the San Diego Convention Center.
Physician Assistant Brandon Guth Earns Reid Health’s Advanced Practice Provider of the Year Award
Brandon Guth, PA-C, a physician assistant with Reid Medical Associates, is the second recipient of Reid Health’s Advanced Practice Provider (APP) of the Year Award for his commitment to clinical …
Providence Opens New Rural Health Clinic in Polson
Just over a year after breaking ground on a rural health clinic in Polson, community members, donors and hospital staff gathered Sept. 30 in front of the new building just behind Providence St. Joseph Medical Center. “Over the years we’ve heard about this need over and over again,” Chief Executive for Providence Montana Krissy Petersen […]
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth
Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine
The challenge of measuring clinical value in mental health
Clients need assurances that high-cost medications flooding the system are aligned with the clinical support needed to improve mental health.
From floating saunas to clinical trials: How heat might help mental health
While scientists have a decent understanding of how sauna and other forms of heat exposure exercises our cardiovascular system, they know relatively little about its impact on mental health.
From floating saunas to clinical trials: How heat might help mental health
While scientists have a decent understanding of how sauna and other forms of heat exposure exercises our cardiovascular system, they know relatively little about its impact on mental health.
From floating saunas to clinical trials: How heat might help mental health
Many people are turning to sauna because of its benefits for their mental health. While scientists have a decent understanding of how sauna — and other forms of heat exposure — exercises our cardiovascular system, they know relatively little about its impact on depression, anxiety and mood. But more studies are being done to understand this connection and why heat appears to act as a powerful antidepressant. NPR's Will Stone visits a "floating sauna village" in Oslo where a husband-wife team are conducting one of the first trials on the link between sauna and mental health — and talks to one of the leading researchers in the U.S about her efforts to study this. Morning Edition consumer health segment for October 5
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Teddy Bear Clinic at Kootenai Health
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Mobile healthcare clinic set up provide free services
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Doctors, insurers sue Newsom over health insurance premium increases
The California Medical Association and California Association of Health Plans say the tax violates Proposition 35, passed by voters in 2024.
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Fulton County pairs deputies with mental health clinicians to help keep people in crisis out of jail
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Fulton County pairs deputies with mental health clinicians to help keep people in crisis out of jail
VB Health Launches Public Seven-Part Supplement Quality Standard
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Inside the study for a remedy to fight Congo’s deadliest Ebola outbreak
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$55 million student wellness center project breaks ground at Michigan Tech
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Cabell-Huntington Health Department hosts drive-thru flu shot clinic
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Why Is CVS Health (CVS) Reworking Primary Care Around Value Based Care?
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Doctors, insurers sue Newsom over health insurance premium increases
California lawmakers passed a healthcare tax in June that could increase premiums by $100 annually, but groups representing doctors and insurers say it violates the law.