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Mark Carney tries to soothe US fears in EU speech after move to become member
Canadian Prime Minister Mark Carney tried to soothe U.S. fears over his overtures toward the European Union, pledging that a planned new partnership wouldn’t be detrimental to the United States. Carney outlined his vision for the planned first-of-its-kind alliance with the EU in a speech to the European Parliament in Strasbourg, France, on Thursday, a […]
Romania's president nominates a new prime minister to break a political deadlock
BUCHAREST, Romania (AP) — Romanian President Nicusor Dan nominated Liberal European lawmaker Siegfried Muresan on Thursday to be prime minister as he seeks to end a monthslong political crisis after his previous two picks failed.
Meet Artem Stepanov, the record-breaking ‘Ukrainian Haaland’
European football rarely has to wait long for its next breakout talent. Artem Stepanov is making a compelling case to be one of 2026/27's.The 19-year-old has had a record-breaking start to the season ...
The Champions League cloud that casts a long, dark shadow
More than a year on from one of their most embarrassing European exits, Celtic are struggling to escape from a groundhog day entirely of their own making. Amid buzz phrases like "learning lessons" and "wake-up calls" following last weekend's derby drubbing at Ibrox, an interesting yet awkward question emerges: have Celtic learned anything at all from last year's costly mistakes? Going out of the Champions League to Kairat Almaty cast a cloud over huge swathes of last season.
Carney embraces EU associate membership proposal as Trump pushes Canada closer to Europe
Canadian Prime Minister Mark Carney on Thursday embraced the prospect of his country becoming the European Union’s first associate member, saying closer ties with the continent would ensure no country could control Canada’s markets or undermine its sovereignty.
The Latest: Trump says EU allowing Canada as associate member could be a ‘hostile act’
President Donald Trump suggested that the European Union allowing Canada to become an associate member could be a “hostile act” and threatened to respond to the proposed move by imposing more tariffs on the bloc
Cherries fans hail historic day in San Sebastian
AFC Bournemouth fans gather in San Sebastian ahead of the club's first European fixture.
Canada looks to deepen research and education links with the EU
Canada is looking for deeper research and education links with the EU, according to its prime minister, Mark Carney. His comments followed hard on the heels of an offer from European Commission President Ursula von der Leyen to give his nation associate membership of the EU, a status that currently has no legal status or definition. Both sides have yet to detail how this newfound political enthusiasm will translate into concrete action.Addressing the European Parliament on September 17, Carney cited both the Horizon Europe research and innovation programme and the Erasmus+ student mobility scheme as areas for future collaboration.Association with the next iteration of Horizon Europe “would allow us to pool resources, cooperate on frontier technology, leverage our world-class research institutes and universities,” he told MEPs. Canada joined the present programme in 2024, but only takes part in Pillar 2, which supports collaborative research projects. Carney also said that young people should be allowed to work, study and live where they want, on either side of the Atlantic. “Canadian membership of Erasmus+ would give your students and ours more opportunity to learn at some of the world’s top universities, to broaden their horizon and to build those lasting ties that will sustain our alliance,” he said.Limited exchanges with Canada are already possible, for example in the Erasmus Mundus strand of the scheme, which supports joint master’s programmes. This would be considerably increased if the country became a full associate member, a club currently limited to nations neighbouring the EU.Most favoured nation?As for the offer of associate membership of the EU, the aim would be to build “an alliance for the future to create a common prosperity and economic security base,” von der Leyen said during her state of the European Union address, also in the European Parliament in Strasbourg, on September 16.“We will work on intelligent manufacturing,” she went on. “We will create a tech alliance. We will integrate defence industrial bases. We will make the Arctic a flagship joint project. We will work on energy-critical minerals and batteries, on [artificial intelligence], quantum, cyber and economic security.”Mona Nemer, Canada’s chief science advisor, told Science|Business that the political speeches by Carney and Von der Leyen will open the door to even more scientific cooperation between Canada and the EU. She even attributed the broader political partnership to the scientific diplomacy of Horizon Europe association. “The science and research collaborations have predated this political rapprochement,” she said.While she is not part of the government decision-making process, Nemer thinks Carney’s speech in the European Parliament is more than “political posturing” and the Canadian government is likely to come up with more practical ideas for how to boost collaboration in the near future. “The prime minister mentioned Horizon [Europe] and Erasmus+, maybe there is something more concrete around this,” she said.She went on to suggest that Canada and Europe could also work more closely together on setting international standards for emerging technologies, AI safety, data sovereignty and joint research infrastructures, such as particle accelerators and marine research fleets.Nemer confirmed that science cooperation will be on the agenda at an upcoming EU-Canada summit in October. She met recently with EU ambassadors to Canada to "see where the possibilities are, to signal that there is interest."Room for expansionLike other countries outside Europe that are associated to Horizon Europe, such as South Korea, Australia or Japan, Canada is not allowed to host European Research Council (ERC) grantees. However, Canadian universities hint they would like re-open that discussion. “Canada’s participation in Horizon Europe, the world's largest research funding programme, has been a big success,” said Robert Asselin, the chief executive of U15 Canada, an umbrella body for some of the country’s biggest research universities, in a statement. “Ensuring swift re-association to the next research programme, will be vital to maintain this momentum. We would welcome efforts to explore further opportunities to collaborate with European partners, such as through the European Research Council,” he said. Related articlesHow a new multilateral defence bank could boost innovationEurope’s independence hinges on innovation, von der Leyen saysBut so far, there are no details from the Commission on how von der Leyen’s proposal would boost Canadian access to the ERC or other sensitive research calls in Horizon Europe. And it is unclear how other non-European associated countries, such as New Zealand or Australia, would react if Canada was given better access than them. The same questions may arise closer to home. “How would a new category of associate member of the EU differ from Norway’s participation in EU programmes through the European Economic Area?” asked Jan Palmowski, secretary general of the Guild of European Research-Intensive Universities. “And how does this proposal for Canada change discussion for the UK, Norway and Switzerland for the next Multiannual Financial Framework?”Another area for discussion is how far Canadian organisations can participate in sensitive projects. “I would expect some of the most crucial issues at hand to be whether Canada can participate more closely and predictably in calls that are deemed sensitive on research security or EU preference grounds, on critical technologies, for instance,” Palmowski said. Canada’s participation in other parts of Horizon Europe, as well as the European Competitiveness Fund, might also be discussed, he added.Whatever the details, closer cooperation between the EU and Canada represents a “substantial” opportunity, according to Mattias Björnmalm, secretary general of the Cesaer university group. “Scientific excellence depends on talented people being able to work together, exchange knowledge and access complementary expertise and infrastructure,” he said. “A closer EU-Canada partnership would strengthen these conditions and provide greater certainty for long-term collaboration.”
The Strange New Politics of AI. Plus. . .
It’s Thursday, September 17. This is The Front Page, your daily window into the world of The Free Press—and our take on the world at large. Today: Douglas Murray asks, why do we allow terrorists to die of old age? The American nonprofits backing Hamas. A conversation with Dara Horn and Coleman Hughes. And much more. But first: inside the unlikely coalition warning that AI may kill us all. Last week, an AI researcher named Jacob Coxon made headlines around the world after saying that he had resigned from Anthropic because he believes AI might cause human extinction—and his co-workers do, too. Unlike the rest of us, potentially, the story just won’t die. The Pro-Human Assembly, a conference held Tuesday in Washington, D.C., about the existential dangers of artificial intelligence, couldn’t have come at a better time—or with a more eclectic coalition. The Archbishop of San Francisco was there. So was Steve Bannon, screaming about the Chinese. Bernie Sanders did a quasi-dramatic reading of messages posted to an online forum by rogue AI agents. Ashley Judd paraphrased a graphic Andrea Dworkin quote for reasons that remain a mystery to me still. It was odd. People in the AI industry have talked openly about the possibility of this technology causing human extinction for years, but it hits differently in the wake of the Hugging Face incident. If you don’t know what that is, all the more reason to read my dispatch today. As the doomers see it, the best-case scenario is a future in which humans are basically kept as pets: well cared for, but with zero autonomy. The worst-case scenario, obviously, is the everyone dies thing. What should be done? I heard lots of ideas but no easy answers. There are currently zero federal regulations on AI, which is sort of strange even to think about. After all, we regulate microwaves, and the people running the microwave industry have never once refused to rule out the possibility that their products will end all human life on Earth. What I saw in D.C. left me even more convinced that you would be hard-pressed to find anyone who believes nothing should be done. You know, except for President Trump. — River Page River Page • Tech and Business [ The AI Doomers Have a Plan to Save Us. I Went to Find Out What It Is. ](https://www.thefp.com/p/the-ai-doomers-have-plan-save-bernie-sanders-bannon) Read story How Robert Kraft Made Macklemore a Martyr—and How to Better Fight Antisemitism On Monday, New England Patriots owner Robert Kraft and a group of other NFL owners banned Macklemore from performing at their stadiums after the rapper delivered a “Free Palestine” speech while opening for Ed Sheeran. Kraft cited the rapper’s “broader history of antisemitic rhetoric and imagery.” Once multiple venues refused to host shows with Macklemore on the lineup, the tour’s promoter officially dropped him. Today, Josh Kaplan says that the move was counterproductive, arguing that though well-intentioned, Kraft’s decision turned an irrelevant footnote into a martyr. “You cannot cancel people into liking you,” Josh writes. Read his column on what a better response to Macklemore would have looked like. Read [ Robert Kraft Made Macklemore a Martyr ](https://www.thefp.com/p/robert-kraft-made-macklemore-martyr-antisemitism-palestine) This raises the question: What actually works against antisemitism? On the latest episode of Conversations with Coleman, recorded in front of a live audience in New York, Dara Horn joins Coleman Hughes to talk about her new book The Final Solution to the Jewish Question. She argues that antisemitism is a script that has repeated itself across countries and ideologies, and that most people don’t understand that well enough to fight it. Don’t miss their conversation. Watch [ The Lie at the Center of Antisemitism, with Dara Horn ](https://www.thefp.com/p/the-lie-at-the-center-of-antisemitism-coleman-hughes-dana-horn) Listen now Douglas Murray • U.S. Politics [ Douglas Murray: The 9/11 Failure That Still Haunts America ](https://www.thefp.com/p/douglas-murray-911-failure-justice-terrorist-guantanamo-bay) Twenty-five years after the September 11 attacks, the men who planned them have still not faced trial. Khalid Sheikh Mohammed and most of the accused have been locked up in Guantanamo Bay since 2002. Judges have retired, and plea deals have collapsed. Today, Douglas Murray examines how this happened and argues that a justice system that allows terrorists to die of old age in an interminable pretrial process is one that has failed. Read his latest column on what that failure says about our unpreparedness for the era we are now living in. Read story The Editors • U.S. Politics [ When Nonprofits Support Terrorists ](https://www.thefp.com/p/when-nonprofits-support-terrorists) A newly declassified CIA brief from 1998 found that Osama bin Laden used nonprofit shell organizations—including U.S.-based Islamic groups—to fund his terror plots. Today, a similar story is unfolding as multiple organizations on American soil present themselves as nonprofits, taking advantage of tax-exempt status while seeking to advance the ideological mission of terrorist groups like Hamas. Read our editorial on the latest evidence of this dangerous trend—and why there’s no excuse for making the same mistake the CIA revealed 28 years ago. Read story Simon Sebag Montefiore and Bari Weiss Live in New York For decades, the Middle East has shaped American foreign policy and loomed large in the public consciousness. Few understand its influence on our politics better than Simon Sebag Montefiore, who argues that America’s quagmires in the Middle East stem from a deep misunderstanding of the region—on both the left and the right. Join him October 1 as he sits down with Bari Weiss live in New York City to kick off his U.S. book tour for The Cauldron: The Making of the Modern Middle East. Get Tickets Now MORE FROM THE FREE PRESS [ Sydney Sweeney’s Naked Truth ](https://www.thefp.com/p/sydney-sweeneys-naked-truth-caitlin-flanagan) Caitlin Flanagan Read story [ I Thought Ukraine Was Losing. Then I Was Almost Hit by a Russian Drone. ](https://www.thefp.com/p/elliot-ackerman-ukraine-drone-gas-station-train) Elliot Ackerman Read story [ The Dangerous Ideology Behind the AI Warnings ](https://www.thefp.com/p/dangerous-ideology-effective-altruism-artificial-intelligence) Shyam Sankar Read story [ Amanda Knox: Patrick Clancy Can’t Win ](https://www.thefp.com/p/amanda-knox-patrick-clancy-grief-internet-crime) Amanda Knox Read story THE NEWS The Federal Reserve raised interest rates by a quarter point, its first hike since 2023, signaling that another increase could follow as the central bank tries to bring inflation under control. President Donald Trump fired back by demanding that rates be cut sharply, though he stopped short of criticizing Fed Chair Kevin Warsh by name. The Houthis fired drones and missiles at Saudi Arabia on Wednesday, including a major oil port on the Red Sea, and Saudi jets struck back with air strikes across Yemen in an escalating front of the Middle East war. (For more on the Houthis, read Zineb Riboua’s column from earlier this week.) A sweeping Russia and Iran sanctions bill passed the House in a 262–159 vote and is now heading to Trump for his signature. Named after the late senator Lindsey Graham, the legislation would hit countries that purchase large volumes of Russian oil and gas with tariffs of up to 100 percent, and is aimed at cutting off revenue that funds Russia’s war in Ukraine. European Commission president Ursula von der Leyen proposed making Canada the European Union’s first-ever “associate member,” drawing a standing ovation from European lawmakers. The proposal, framed as a response to a world grown more hostile, faces an uncertain path as EU member states would have to approve it, and one diplomat said that “nobody really knows what it means.” The House voted unanimously to send billionaire Leon Black a criminal contempt referral after he defied a congressional subpoena to testify and hand over documents related to his connections to Jeffrey Epstein. Black chose to fight the subpoena in court rather than comply. Charlie Kirk’s family filed a wrongful death notice Wednesday against Utah Valley University, alleging that a series of security failures left him exposed to a rooftop sniper. The notice is a required legal step before the family can sue. Merriam-Webster added 1,400 words and definitions to its dictionary, including looksmaxxing, vibe coding, and cuffing season. The publisher said the new entries offer “a window into the world today.” The Free Press earns a commission from any purchases made through all book links in this article.
Celtic vs Ferencvaros – Match preview and team news
Celtic is set to host Ferencvaros in their opening Europa League fixture on Thursday at Celtic Park.Martin O’Neill’s men will look to start their European campaign on a strong note after their rec...
New platform launched to help stroke survivors and families “understand the science shaping stroke care”
The European Stroke Organisation (ESO)—in partnership with the Survivors Honouring Inclusion, Networking and Empowerment (SHINE) Global Stroke Collaboration—today announced the launch of Stroke Insights, a new online platform designed to translate complex stroke science into clear, trusted and practical information, ensuring stroke survivors and their families can navigate the latest medical research in a more […]
Scientists Overhaul Giant Particle Collider in Search of Universe’s Hidden Building Blocks
The European Organization for Nuclear Research, or CERN, will dismantle the Large Hadron Collider, which helped discover the so-called God Particle, in order to build a more powerful particle accelerator.
Fans' loyalty rewarded by Europa League win
Former Sunderland striker Marco Gabbiadini reflected on a "special" Europa League victory as the club made a winning return to European football after 53 years away. The winning moment against AZ Alkmaar came in the 66th minute when Enzo le Fee slotted away his penalty after being brought down inside the area. "It was very special," Gabbiadini told BBC Radio 5 Live's Football Daily.
Juventus v NEC Nijmegen match preview and prediction
Juventus host NEC in their first European game of the season as the men in black and white look to recover from their poor run of form in their last two matches.Most people expected Juve to have a bet...
Juventus vs NEC Nijmegen – Predicted lineup and team news
Juventus are set to begin their Europa League journey with a home match against NEC Nijmegen at the Allianz Stadium on Thursday evening.The Italian giants head into this European opener after a shaky ...
Talking Points: European Paradise on Wearside
Collective dreams came into reality as Wearside became a European paradise for a buoyant fanbase after a hard-fought win.
Le Fee provides stardust on Sunderland's special night
You have to go back to a second-round exit at the hands of Portuguese side Sporting in the 1973-74 Cup Winners' Cup for the last time Sunderland played in a major European competition. There were no shortage of individual displays to galvanise them from Robin Roefs with his crucial saves, Granit Xhaka pulling the strings from deep to full-back turned winger Trai Hume causing chaos in the opponents' box one moment and throwing in a crunching tackle to end an AZ break the next. The 26-year-old worked tirelessly off the ball, nicking the ball back for his side time and again, but it is in the final third that the Sunderland playmaker really comes to life.
Trump Wanted Canada as the 51st State. He Ended Up Pushing It Toward the European Union.
The invitation by the E.U. for Canada to become an “associate member” is a sign of Mr. Trump’s brand of diplomacy, which often involves threatening America’s closest friends.
Garner crucial for Everton's European push
James Garner's consistent displays last season earned him a first England cap in a friendly against Uruguay in March. After the match, England manager Thomas Tuchel compared him with Uruguay and Real Madrid midfielder Federico Valverde. "He's our mini Valverde," said Tuchel.
EU Proposes 'Kids Act' Banning Social Media Under 13 Over Mental Health Risks
Framing youth digital safety as an urgent public health priority, European Commission President Ursula von der Leyen announced sweeping digital health protections for minors on Wednesday (16 September) in Brussels, introducing the “EU Kids Act” to restrict online platform access.
Eating four to six wholegrain servings daily protects heart health
Eating four to six servings of wholegrain each day reduces several major risk factors for cardiovascular disease, according to a new study published in the European Heart Journal today (Wednesday).
Ukrainian defence tech seeks new ways to scale up
Since Russia's full-scale invasion in February 2022, Ukraine's defence sector has expanded several-fold, becoming a significant source of military innovation, especially in unmanned systems, counter-drone technologies, electronic warfare and AI-driven combat systems. But finding the funds and personnel to scale up and to reach international markets remains a challenge.Spurred on by the demands of the front-line, Ukrainian defence companies say they can develop a minor component in a couple of weeks, or major hardware or software solutions within a year. This is several times faster than the usual development cycles in the sector. Tencore, founded in 2024, is now one of Ukraine’s largest providers of unmanned ground vehicles, well exceeding the production of NATO members in this category. Odd Systems, a Ukrainian combat cameras developer founded in 2023, launched its first thermal camera in 2024. Less than two years later, it is developing the fourth generation of the product, one that has evolved into a full vision system.According to Michael Singer, managing partner at Verne Capital, a venture capital fund supporting defence companies in Europe, this speed is down to the short feedback loop between the developer and the end user. “Ukrainian companies develop technologies in close interaction with soldiers and military units, test them under real combat conditions and rapidly incorporate feedback into the next generation of the product,” he says. “Sometimes we need to react to feedback and deploy an upgrade within hours,” says Polina Tymchenko, the spokesperson for Himera, which develops electronic warfare-resistant walkie-talkies. “It means that, as a company, you have to have a higher tolerance for risk, and also design your products in a way that fosters those quick changes.”Getting a product deployed by a combat command involves no paperwork other than a purchase order, says Perry Boyle, co-founder and chief executive of Mits Capital, a Ukrainian-US investment group focused on attracting capital for Ukraine's defence tech sector. “New weapons can be developed and deployed based largely on handshakes.”Nevertheless, the speed of development is largely subject to the level of funding, says Iryna Sukhomlyn, head of business development at RMachine, a developer of unmanned ground systems. “Financial support needs to start much earlier, particularly at technology readiness level 3-5, not only when most of the technological risk has already been removed,” she says.In 2025, Ukrainian defence tech companies attracted about $129 million in investment, with the true figure likely higher given the share of undisclosed security-sensitive deals, according to a report published by the Kyiv School of Economics. These investments were primarily concentrated in the AI and software segment, as they are considered a lower financial risk.Scaling production is a major barrierAccording to Iryna Supruniuk, business development director at Odd Systems, proving a defence product in Ukraine is not the end of the development process, but the beginning of a continuous evolution, since operational requirements change rapidly. “Continuous iteration remains our highest priority,” she says.It's also when production must scale up, which represents a major hurdle. “Scaling production requires capital, manufacturing capacity, components, certification, procurement access and reliable supply chains,” Singer says. Scale-up is also hampered by demographic pressures, especially a shortage of young specialists needed to expand engineering teams. Companies have reported struggling to replace specialists lost due to Russian attacks, mobilisation and emigration. In order to meet this scale-up challenge and finance arms production, begun allowing defence technologies to be exported, assuming it has an excess capacity. It has also announced the creation of ten defence and weapons export centres across Europe by the end of 2026.According to Singer, a technology that has demonstrated its value under real combat conditions has a fundamentally different credibility than a product that has only been tested in a laboratory or training environment. But combat validation alone doesn’t automatically create an international business. “Companies still need access to foreign defence ministries and procurement organisations, international certification, financing for production scale-up and, in many cases, local industrial partners,” he says.Already in 2026, the EU has signed several agreements with Ukraine that aim at joint defence technology development and production. These include allowing Ukraine to join the European Defence Fund, signing a financing agreement under the European Defence Industry Programme, and setting up the EU-Ukraine Drone Alliance.For Singer, it is important that European defence companies don’t just see their Ukrainian partners as technology suppliers, but rather as potential innovation partners. “Ukrainian companies bring speed, operational experience and an exceptional ability to iterate. European partners can provide industrial capacity, capital, established supply chains and access to European procurement markets.”Procurement possibilitiesWhen it comes to exports, the procurement and compliance processes involved require time, taking months or even years, and money. In other words, resources that small defence tech companies need if they are to improve and scale up their technologies. According to Sukhomlyn of RMachine, if the priority is to rapidly increase available defence capabilities, then the processes need to reflect that urgency. “If Europe wants defence innovation at wartime speed, its administrative processes also need to operate much closer to wartime speed,” she says, highlighting a need for support with certification, market access and mutual recognition of relevant testing. “Otherwise, we risk having excellent technology available but spending years making it administratively eligible to be purchased.”Related articlesRussia widens targeting of European research centresEU must support research managers in central and eastern Europe, says Visegrad fund headThis is a lesson Europe’s defence sector would do well to learn, Singer says. “Defence innovation needs to be organised around the speed and requirements of the end user, not around the speed of the bureaucracy.”Supruniuk says the European defence sector should rethink the balance between quality and quantity. “In many cases, a good-enough system available in thousands of units creates greater operational value than a perfect system available in dozens.”“For decades, everyone has been looking for that all-powerful, exquisite system that can protect everyone,” adds Tymchenko. “We see in crime that only scalable, dedicated, affordable solutions can actually defend democracies.”
EU membership bid gives boost to Moldova’s fledgling R&D landscape
Moldova’s push to join the EU is having the spillover effect of helping to improve the country’s R&D landscape, which in recent years has suffered from fragmentation, decreasing personnel and a lack of research infrastructure.The country became an EU candidate country in 2022, alongside Ukraine, and officially began accession negotiations in 2024. With a pro-EU government, Moldova has been actively carrying out reforms to align with EU standards. This has helped accelerate the development of R&D, said Igor Chiosa, acting head of the Research and Innovation Policy Directorate at Moldova’s Ministry of Education and Research. “Our R&D landscape is moving up, and we are more and more involved in the European Research Area,” he said. “The support we receive from the EU is very important, not only financially, but also because of incentives, consultation and capacity building.”The R&D landscape in the former Soviet republic is still relatively underdeveloped, despite attempts at improvement going back to a 2004 law on science and innovation and later reforms in 2017 and 2018. But the system remains in a “precarious situation” and “in the process of contraction,” according to an assessment carried out by the government for the current National Programme for Research and Innovation, which runs from 2024 to 2027. The analysis highlights in particular the declining number of researchers and PhDs, which has been continuously falling, as well as limited research funding. This is around 10 times lower than the EU average and “insufficient to maintain a level of research activity that supports higher education and meets the needs of the economy.” The mechanisms for allocating research funds are also described as inefficient, as well as the general fragmentation of the landscape, with research and innovation activities being carried out in 67 different places. The lack of strategic vision for research infrastructure is also noted. The strategy sets out to address these issues and is being fuelled by reforms linked to EU accession. Moldova now has a regulation on open science and gender equality. There is also a new support mechanism for technology transfer offices and a business-academia roadmap. In 2025, the country also became the first Eastern Partnership country to approve a Smart Specialisation strategy, which will coordinate its R&D efforts to focus on strengths, within a European context. “We’ve done a lot in terms of normative acts,” Chiosa said. Horizon Europe successMoldova is also seeing more success in the EU’s flagship R&D programme, Horizon Europe. The country has now won nearly €15 million in funding, already double the amount won under the previous programme, Horizon 2020, and more than the €10 million target set by the government. Chiosa said the priority has shifted now to winning more research-centred projects, rather than those related to support and capacity. Moldova is also targeting further involvement in large European projects. Last year, it joined the EuroHPC Joint Undertaking giving Moldovans access to Europe's supercomputing network. The country is also a member of Danubius-RI, a European research infrastructure focused on river and sea research. Despite these efforts, Moldova’s research capacity is still shackled by its limited R&D budget, which equates to 0.23% of its GDP. This is around half of what its neighbour Romania spends, which is the lowest in the EU. According to Chiosa, the research budget is increasing year-on-year, jumping by €6.34 million between 2024 and 2025. But this doesn’t show up when looking at it as a proportion of GDP. “Of course, it’s difficult,” he said. “That is why we are putting more emphasis on collaboration between business and academia, as well as participation in Horizon Europe, to try to diversify our sources of funding.”A World Bank loan of €30 million, plus a grant of €7.8 million, was agreed in 2025 to support the modernisation of Moldova’s universities. As part of this, a call was launched this year to provide universities grants of up to €900,000 to develop their research infrastructure. Moldova is also collaborating closely with Romania, with which it shares a common language, funding 100 joint projects in 2023 and 2024. This support has been instrumental. “They are helping with sharing their expertise, inviting us into consortia, and lots more,” Chiosa said. Looking forward, Moldova is eagerly anticipating joining the EU. “We are looking closely at what the EU is doing and will shape our future national programme in research innovation accordingly.”EU accession “blocked at a technical level”Moldova is aiming to join the EU by 2028, but despite its swift and eager efforts to meet the accession criteria, there remain obstacles outside of the country’s control. For a country to join the EU, it must have certain legislation in place and meet specific standards in various areas. This is categorised into six thematic clusters containing 33 chapters. Moldova and the EU have so far opened two of the clusters, numbers one and six. The first covers fundamental laws, such as the judiciary, security and financial legislation. The sixth covers external relations. The remaining four clusters are still unopened. This includes the third cluster, on competitiveness and growth, which contains the chapter on science and research.Related articlesQ&A: Albania’s ambition to become a ‘moderate innovator’Data corner: Horizon success rates are droppingThe European Commission has confirmed that these clusters are ready to be opened, with an official saying that the Commission is encouraging EU governments, who have the final say, to move forward on the matter. However, both clusters two and three remain blocked by the EU Council’s working party on enlargement and countries negotiating accession to the EU, a different official, representing the Council, confirmed.This working party is set to meet several times in the coming weeks, with a Council meeting scheduled for mid-October in which enlargement, and Moldova’s bid, will be discussed. But there is no certainty that these talks will lead to progress. According to the Council source, it is “completely impossible to foresee if and when the file will be unblocked,” citing the sensitivity of the matter. Moldova’s situation is particularly complicated. One factor is that it borders Ukraine and is increasingly embroiled in Russia’s war, with drone incursions occurring more often on its territory. Another is Transnistria, a Russian-backed breakaway state that lies within the territory of Moldova. It is unclear how the EU would be able to accept Moldova into the bloc while this situation remains unchanged. While there is no direct reason to delay opening cluster three with Moldova, as it covers matters unrelated to security, it could be that the EU is reluctant to speed through accession negotiations without first resolving broader, geopolitical issues.Chiosa is confident that, if and when the chapter on science and research is opened, Moldova will be able to finalise it quickly. It doesn’t require any legislative changes and is only a matter of proving certain standards, which Chiosa believes Moldova is well prepared to do. “We hope that chapter 25 on science and research will be one of the first chapters opened and closed,” he said.
Aurora Cannabis Provides Business Update; Accretive Acquisition of Safari Flower Company and Leading European Performance Expected to Fuel International Growth in the Fiscal Second Quarter 2027 and Beyond
NASDAQ| TSX: ACB Re-affirms FY27 Q2 guidance for sequential growth in quarterly net revenue and adjusted EBITDA1 Following the receipt of EU-GMP certification...
Chelsea and Arsenal are watching Brazilian teenager
Arsenal are no strangers to unearthing talent in the Brazilian league, and the Gunners have identified another young player who could shine in European football in the coming years.They have scouts mo...
i-payout Expands U.S. Money Transmitter Licensing Footprint and Advances European EMI Strategy
FORT LAUDERDALE, Fla., Sept. 16, 2026 (GLOBE NEWSWIRE) -- Expanded regulatory infrastructure is designed to give marketplaces, gig economy platf...
Canada offered status as EU’s first associate member
'This is a partnership not against anyone else, but for our common strength,' says the European Commission president
'Too early' - fan views on European football talk
In the meantime, the ride is the best in years and all the fans and pundits who thought Daniel Farke wasn't up to the job need to eat humble pie. Julian: Whilst I am proud with the way we are playing and believe that we have a really strong squad, I think it will be too early to go into Europe next season. John: All the talk about Europe is very premature.
Sunderland v AZ Alkmaar: Our Europa League Predictions Are In
European football is finally back on Wearside, but how do the Roker Report team see Sunderland faring against AZ Alkmaar on this historic night?
Sunderland vs AZ Alkmaar predictions: Europa League tips and odds
Sunderland play their first match in European competition since 1973 tonight, when they kick off their Europa League campaign against AZ Alkmaar at the Stadium of Light (kick-off, 8pm).
Europa League opener perfectly timed for Celtic after Ibrox shambles
A European clash before a vital Glasgow Derby is usually seen as a hindrance, but this is one that could benefit Celtic greatly…Martin O’Neill, Manager of Celtic, arrives at the stadium before the...
AC Milan vs Benfica – Match preview and team news
AC Milan will kick off their European journey on Wednesday, facing Benfica in their first Europa League match of the season at the San Siro.AC Milan vs Benfica – Match preview and team newsDate: We...
Sunderland’s European Adventure Is About More Than Football
As Sunderland prepare for their first European home game in 53 years, could the Lads and their supporters learn something from a whole new football culture?
For Those Who Dreamed of Seeing Sunderland in Europe
As Sunderland finally return to European football, one supporter reflects on the people who dreamed of nights like this but never got the chance to see them.
Herndon satellite business launches Luxembourg subsidiary
HawkEye 360 on Tuesday announced plans to establish its first European subsidiary, HawkEye 360 Luxembourg, S.à r.l.
Can Bournemouth Have Their Europe Cake and Eat It?
Historic European nights beckon for the Cherries, but cautionary tales of domestic collapse loom. Dive into the squad depth dilemma facing Marco Rose as he balances continental glory.
Vega launches two Earth science satellites
A Vega C rocket successfully launched a pair of Earth observation satellites for the European Space Agency and the European Commission on Sept. 14.
Bayer Leverkusen Begin Their Europa League Campaign Against Celje
Fresh off a frustrating domestic draw, the German giants must sharpen their clinical edge against goal-hungry Slovenian champions to ignite another deep run toward European silverware.
Morgan Stanley turns more hawkish, forecasts two Fed hikes and ECB move
Morgan Stanley has joined other major Wall Street banks in adopting a more hawkish outlook on interest rates, forecasting U.S. Federal Reserve rate hikes and another European Central Bank increase later this year as inflationary pressures persist.
A Gold Medal and a Breakthrough for Leipzig’s Young Stars
Elite prospects Mirja Kropp and Marie Kleemann secure landmark Fritz Walter Medals, cementing their status as the future of German football following a dominant U17 European Championship triumph.
PDO Chios Mastiha: Ancient Greek Tradition Meets Modern Science
From a legendary ingredient collected since ancient times to a versatile addition to the modern kitchen, PDO Chios Mastiha is bringing a distinctive taste of Greece to Canadian consumers. Produced exclusively in Mastichohora, in the southern part of Chios island, Mastiha owes its unique character to the region's particular soil and climate conditions, while its complex natural composition continues to attract scientific interest. Featured through the "Premium European Products: Better Knowledge,
Swedish elections on a knife-edge
A ‘razor-thin’ victory for the centre-left is forecast but not certain, in a result that tests the temperature of European politics
fiskaly appoints Co-CEO to accelerate European growth
VIENNA--(BUSINESS WIRE)--Sep 14, 2026--
Juventus target has decided to leave European football
Juventus were desperate to sign a new left-back in the last summer transfer window, and one of the players on their radar was Emerson Palmieri, with the Marseille defender opening the door for the mov...
European science calls for ambitious investment in research: "Current decisions determine Europe's future. We are falling behind China and the USA"
"To remain global leaders, a competitive economic power, and a sovereign actor, Europe needs strong science and innovation." Seven scientific organizations, representing...
Only Ibrahimović has done as well as Ferran Torres 🦈
The Shark.This Sunday evening, PSG are trying to secure their first Ligue 1 win of the season away at Stade Brestois.The reigning back-to-back European champions made the perfect start to the match, t...
Swedish voters go to polls to choose a new parliament as hard right bids for role in government
Prime Minister Ulf Kristersson is seeking a second four-year term at the helm of the European Union nation that is also NATO’s newest member. Meanwhile, his predecessor hopes to win the job back.
European Commission backs out of conference after surprise Taiwanese participation
Senior MEP Pina Picerno linked the move to complaints from China
Iraola Talk: Reds Lacked Freshness in Scoreless Draw
It is not unsual to be fatigued after a European night, but it is something Iraola will have to learn to deal with.
Crypto billionaires donate millions to Reform UK, raising concerns about money in politics
Reform UK, the anti-immigration party led by Nigel Farage, received £72 million (around €83.9 million) from two cryptocurrency billionaires this weekend, prompting concerns about money’s influence in British politics. Ben Delo, co-founder of the BitMEX platform, donated £36 million, and crypto investor Christopher Harborne matched that amount. Harborne supports Reform UK’s policies, believing they will […]
On-loan Real Madrid star breaks Lionel Messi record
On-loan Real Madrid starlet Franco Mastantuono on Friday secured for himself a noteworthy piece of European football history. This came owing to his exploits in Fiorentina’s Serie A meeting with Ven...
“Newcastle United, Is My Dream Club” Allan Saint-Maximin
The French winger cements his cult hero status by declaring his enduring love for the Magpies, recalling an electric Tyneside spell that fueled the club's European ascent.
Putin warns European troops in Ukraine would mean war with Russia
The Russian president issued the warning ahead of the BRICS summit in New Delhi.
The dirtiest places on an airplane; testing for a breast cancer gene mutation; the evolution of esophageal cancer; plus other stories with Vanderbilt Health sources
William Schaffner, MD, Professor of Preventive Medicine, was quoted by several news outlets about public health issues, including: WKRN News 2 (heat-related illness); NBC News (how bad will flu and COVID be this winter?); AAA’s The Extra Mile (the dirtiest places on an airplane); WKRN News 2 (again) (measles in Tennessee); and The Tennessean and Healthline (new COVID vaccines). Schaffner also spoke to the EMJ European Medical Journal for a Q&A interview. Tuya Pal, MD, Professor of Medicine, was quoted in a New York Times story about testing for a breast cancer gene mutation. Michael Gibson, MD, PhD, Professor of Medicine, was quoted in a MedPage Today story about the epidemiologic evolution of esophageal cancer. Medpage Today writer Shannon Fritz quoted Shravani Durbhakula, MD, Associate Professor of Pain Medicine, who answered questions about a street drug called cychlorphine. Becker’s Behavioral Health picked up the story. WSMV Channel 4 News reporter Diana Rocco interviewed Michael Caucci, MD, Associate Professor of Psychiatry and Obstetrics and Gynecology, for a story about postpartum psychosis and the trial of Lindsay Clancy.
AFC Bournemouth vs Brentford: Is This A 'Must Win' Game?
Tomorrow, Cherries face an in form Brentford side that are yet to lose so far this season, and with European football soon to start, is this the first must win game of the season for Marco Rose's men?
‘The Europe she fought for will miss her’: Politicians pay tribute to Emma Bonino
The Italian civil rights activist and former European commissioner has died at the age of 78.
📸 This week’s viral Champions League images 🍿
The Champions League is wild! A look at the most bewildering moments from this European week, starting with Michael Olise’s hilarious — and now viral — interview on DAZN. Another surreal Olise ...
Emma Bonino, prominent humanist in Italian politics, dies at 78
A tireless defender of human rights, Emma Bonino served in the Italian and European parliaments, as foreign affairs minister, and as European commissioner. The historic figure of the Italian Radical Party died in Rome on Friday.
🗞️ Raphinha, Lamine Yamal and the Cesc effect: Friday's covers
The sports newspaper front pages this September 11 are packed with big names, continental surprises, and tensions handled in global boardrooms. Barcelona’s takeoff, Como’s European debut, and the ...
Taiwan vice president makes rare Europe visit for conference on democracy
European Parliament's Pina Picierno says Hsiao's visit 'was kept secret until her arrival to protect her participation'.
Wasps are disappearing this summer, and scientists are worried
Britain’s wasps have become mysteriously scarce this summer, and scientists suspect an unusual combination of temperature swings, heatwaves, and food shortages may be responsible. Even the wasps that remain appear unusually small, potentially offering a glimpse of how extreme heat could reshape insect populations.
Scientists say August was Earth's hottest month they've measured
The European climate service Copernicus said the Earth just sweltered through its hottest month on record in August. Scientists said the heat surge is mostly due to human-caused climate change.
The Sidemen Rep Arcade Signs Max Fosh, Friends From Work & More Ahead Of Europe’s First Creator Upfront
EXCLUSIVE: Arcade, the management company of The Sidemen, has signed a host of creators, as it relaunches as an entertainment business ahead of its first European upfront. Comedian Max Fosh, creator c...
Spanish Grand Prix 2026: Can football-obsessed Madrid embrace F1?
After F1’s explosion in popularity away from its European heartland the sport is coming home. Why Madrid? Because it is beautiful… and has a very big expo centre on the outskirts.
Yourgene Health Insight DPYD assay achieves IVDR accreditation
Yourgene Health (part of the Novacyt Group), an international molecular diagnostics company with a broad portfolio of integrated technologies and services, announces the commercial launch of its In Vitro Diagnostic Regulation (IVDR)-certified Yourgene® Insight DPYD assay, expanding the Company's clinical genetics portfolio across regulated European markets.
Yourgene Health launches Insight DPYD assay (IVDR)
Yourgene Health (part of the Novacyt Group), an international molecular diagnostics company with a broad portfolio of integrated technologies and services, announces the commercial launch of its In Vitro Diagnostic Regulation (IVDR)-certified Yourgene® Insight DPYD assay, expanding the Company's clinical genetics portfolio across regulated European markets.
Global heat stuck on high. Scientists say August was Earth’s hottest month they’ve measured.
The European climate service Copernicus said the Earth just sweltered through its hottest month on record in August.
Global heat stuck on high. Scientists say August was Earth's hottest month they've measured.
The European climate service Copernicus said the Earth just sweltered through its hottest month on record in August
Global heat stuck on high. Scientists say August was Earth's hottest month they've measured.
The European climate service Copernicus said the Earth just sweltered through its hottest month on record in August.
Viewpoint: Unlocking Europe’s wildfire data
Europe is already investing in the science, technology and infrastructure needed to understand, prevent and fight wildfires. Copernicus provides satellite-based Earth observation and environmental information, while the European Forest Fire Information System provides information on fire danger and forest fires across Europe. Weather and climate systems add forecasts of heat, drought, wind and humidity; historical fire databases show where fires have occurred; and researchers generate increasingly detailed knowledge about fuels, fire behaviour, forecasting, modelling and risk management. Meanwhile, new European research projects are adding digital twins and other tools to this growing ecosystem.However, these data do not necessarily sit together, nor are they necessarily described, structured or governed in ways that allow them to be used together. Much of the information is public, but some is commercially held. Some is sensitive. Some is subject to legal, security or operational restrictions. Even when data can be legally accessed, different systems may use different formats, terminology and rules.Europe therefore faces an unusual paradox: we have vast amounts of relevant information to respond to the wildfire challenge, but not the means to bring it together. For example, a wildfire researcher or emergency service might need to ask whether a particular combination of vegetation, drought, wind and topography has historically been associated with rapid fire spread. The relevant information may exist in several institutions, using different systems and subject to different conditions of access.The challenge is to conduct an authorised analysis that interacts with these sources, combines the results and respects the rules imposed by each data custodian.An important part of the answer can be found in the Fair principles, the idea that data should be findable, accessible, interoperable and reusable. Developed more than a decade ago, these principles have become a central reference point for modern data stewardship, making it easier for people and machines to find data, understand what it means and determine whether it can be reused.Readability by machines is essential, since AI systems will be key to meeting the data challenge. Bring analysis to the dataThe proposition is not to give an AI system unrestricted access to sensitive databases. Quite the opposite. The goal is to make it possible for approved algorithms to go to the data, rather than requiring sensitive data or large datasets to be copied to wherever the analysis happens.Imagine an analysis asking a series of questions of different data stations. At one station it might examine weather and climate data; at another, historical fire records; at another, experimental measurements of fire behaviour. The algorithm does not need to download everything. It can operate within the environment permitted by each data custodian and return only the results that the rules allow to leave.This is sometimes described as data visiting, and related approaches already exist in areas such as federated analysis and federated learning.Sensitive data should therefore not be treated as a free-for-all for machines. This requires appropriate governance at multiple levels. Access needs to be authenticated and authorised. The purpose of an analysis should be defined. The code or model being run should be controlled. Data custodians should be able to specify what can be queried and what results can leave their environment. Activities should be auditable and human oversight should remain where the consequences require it.In other words, the objective is not to trust AI with the data. It is to design systems in which AI never has more access than it needs.As open as possible, as closed as necessaryFair data should also not be confused with open data. Some wildfire data should be openly available. Other information may legitimately need to remain restricted because it concerns critical infrastructure, security, commercial interests, privacy or operational capabilities. The principle should be: as open as possible, as closed as necessary.The important point is that restricted data should not automatically become unusable data. If machines can discover what information exists, understand its meaning, establish where it came from and determine the conditions under which it can be used, authorised analyses can potentially be carried out without the underlying data ever leaving the environment in which it is protected.Restricted data can still be Fair and machine-actionable.This is also an important question of data sovereignty. European institutions should not have to surrender control of their data to a handful of technology platforms in order to benefit from AI. Nor does Europe need to start again by building one giant repository for every piece of wildfire information. The better approach is to connect what already exists.This is the principle behind emerging approaches such as Tryangle, developed through the Leiden Initiative for Fair and Equitable Science. Rather than creating another centralised data warehouse, the approach seeks to provide an interoperable layer through which approved algorithms can visit distributed data sources while respecting the rules of their custodians.In this way, a data station can remain where it is. Its custodians can retain control. Existing databases and applications do not have to be abandoned. What changes is their ability to communicate with other systems through common, machine-readable descriptions, access rules and interoperability mechanisms.But approaches like this need data that meets the Fair principles. Only then can an interoperable ecosystem safely begin to turn fragmented information into collective intelligence.Data infrastructure is wildfire infrastructureThe implications of this approach are entirely practical. Firefighters could gain better intelligence about local and evolving risks. Land managers could test prevention strategies using more comprehensive information about fuels, weather and past fires. Researchers could compare evidence across ecosystems without repeatedly moving huge datasets between institutions. Smaller regions and resource-constrained teams could access analytical capabilities without having to build large data infrastructures themselves.Europe is already investing heavily in satellites, databases, research programmes, forecasting systems and scientific expertise. The question is whether we will connect those investments well enough to turn them into actionable intelligence.That requires policymakers and funders to treat data infrastructure as seriously as physical infrastructure. Data generated or supported through European public funding should be Fair, verifiable and machine actionable by design, wherever legally and ethically possible.Related articlesData Corner: Europe’s burning need for wildfire mitigation researchClimate monitoring must remain a global enterprise, experts sayIn practice, that means funding not only the production of data, but also the infrastructure that makes data usable across systems: metadata, provenance, interoperability, access mechanisms and governance. Where data must remain restricted, we should ensure that it can still be securely discovered, verified and used for authorised analysis.Initiatives such as the European Open Science Cloud offer an existing framework through which these principles can be put into practice. What is needed now is to accelerate implementation and make them a standard part of how Europe funds and builds research and innovation systems.We do not need another generation of disconnected databases. The data is already there. The opportunity is to make it work together, securely, responsibly and quickly enough to help prevent the next fire, rather than simply document the last one.Jean-Claude Burgelman is professor emeritus at the Free University of Brussels (VUB) and editor-in-chief at Frontiers Policy Lab. For more than 20 years he held leading roles in research and innovation policy at the European Commission.
Flying Car With (Tiny) NH Angle Gets the OK in Europe: Business NH Magazine
PAL-V, the Dutch firm that has been working for decades on a flying car held aloft by a helicopter-like rotor, has gotten a production license from the European aviation safety agency.
Nine Years Since Brighton's First Ever Premier League Win
Relive the historic afternoon a Pascal Groß masterclass dismantled West Brom, sparking a transformative journey from top-flight newcomers to European contenders under the lights of the Amex.
Barcelona vs Feyenoord, Champions League: TV & Streaming, Live Thread
Join us for the first Barcelona European adventure of the season!
Europeans struggle to imagine 'credible' future, study finds
New research identifies an 'imagination gap' as where political choices can still matter
Europeans struggle to imagine 'credible' future, finds study
New research identifies an 'imagination gap' as where political choices can still matter
Belgium battle could be a blessing
It is a new chapter for Aston Villa and, against Club Brugge, they turned the page. A first win of the season, albeit more nervy than anticipated, lit the spark for Unai Emery's side. The visitors were in a commanding and deserved position at half-time, John McGinn's opener making him the club's all-time record European goalscorer with 12.
Seagulls must learn from slow start
It's been a busy start to the 2026-27 campaign for Brighton and Fabian Hurzeler must now begin to prepare for a packed schedule of domestic and European football. Although the Seagulls will wait until October for their Conference League league phase to start, Hurzeler's side has endured a flurry of mixed results in their opening five games of the season. After a bruising 4-3 loss at Stamford Bridge to transfer-foes Chelsea, Brighton were lucky to escape with a 1-1 draw at home to Leeds.
Champions League
A new edition of the UEFA Champions League is under way, with Inter opening their 2026/27 European campaign with a defeat away to Real Madrid. Europe’s premier club competition will now take a break...
Porto vs Manchester City Match: Champions League Live Updates
Porto hosts Manchester City at the Estádio do Dragão on Tuesday, September 8, in the opening round of the 2026-27 UEFA Champions League phase. Both teams enter the European opener in strong domestic form and will be looking to start their Champions League campaigns with a positive result. Kickoff is scheduled for 8 p.m. BST, […] The post Porto vs Manchester City Match: Champions League Live Updates appeared first on HEAVY.
Eutelsat Wins Further Connectivity Business in Greenland
Eutelsat is going to help to bring better connectivity to Greenland. Alongside the European Union, the government of Greenland and the government of
Allegri counts on European 'motivation and adrenaline' for Napoli
Coach Massimiliano Allegri is hoping the arrival of Champions League football can help put Napoli on the right track after back-to-back defeats in Serie A. Victory on the opening day against Genoa has been undermined by successive defeats at the hands of Como and Inter Milan, leaving new boss Allegri looking for a reset when his side welcome Arsenal to Stadio Diego Armando Maradona on Wednesday evening.
🚨XIs ready: City visit Porto in their European opener
Estádio do Dragão is getting ready to host an electrifying UEFA Champions League opener. Francesco Farioli’s FC Porto come into it on fire after putting together seven straight wins and opening th...
🚨Confirmed XIs: Dortmund host Villarreal in their European opener
The 2026/27 UEFA Champions League kicks off in style at the mystical Signal Iduna Park. Borussia Dortmund come in as favorites, backed by three straight wins and Serhou Guirassy’s firepower up front...
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
Apple Acquires Startup Working on 'Breakthrough Sensing Technology'
Earlier this year, Apple acquired California-based startup Sonera, according to a notice published today on the European Commission's website. Sonera previously announced that it had developed "breakthrough sensing technology" that "non-invasively measures magnetic fields" generated by the brain and body. The company said its technology can analyze neural data without direct skin contact, giving it an advantage over traditional electrical sensing techniques.
Legal complaint against FIFA to cover impact on women’s schedule
A legal complaint against FIFA has been extended to cover its “abusive conduct” towards the women’s game in Europe. The complaint by the European Leagues umbrella group, which includes the Premier League and Scottish Professional Football League (SPFL) as members, was first lodged with the European Commission in October 2024.
Legal action against Fifa to include women's schedule
Legal action from the top European leagues and global players' union Fifpro against Fifa is extended to include the world governing body's "abusive conduct" towards the women's game.
📺 Follow Napoli's UEFA Champions League journey on NOW!
Napoli are back in the Champions League and getting ready for a new European season packed with major challenges. Massimiliano Allegri’s side will face Arsenal, Manchester City, Porto, Villarreal, C...
Arsenal Predicted XI vs Napoli as Arteta Handed Injury Boost
Mikel Arteta faces a selection dilemma in Naples as key stars return. Discover how Bruno Guimaraes and Ebere Eze could spearhead a refreshed lineup seeking European redemption.
Qualitas Energy buys Cero Generation’s 5.8GW European renewables business
Renewables investment platform Qualitas Energy has bought Cero Generation’s 5.8GW European solar PV and energy storage project portfolio.
Roma slash 26/27 wage bill by 14%
Roma, as stated by Tony D’Amico, has lowered its wage bill as requested by UEFA to send a positive message to European football’s governing body. The Roman club is moving toward sustainability, wh...
Exclusive: Daryl Mitchell backs ETPL to produce cricket's next superstars
Daryl Mitchell is one of the big names taking part in the inaugural European T20 Premier League this season with the Dublin Guardians, and the New Zealand international is backing the new franchise league to make a huge mark.
Eight Italy hopefuls to watch in Tuesday’s Champions League matches
Champions League football gets underway for the 2026-27 season on Tuesday evening, and ahead of kick-off at 17.45 BST, here is a look at the eight Italy hopefuls that could be involved in European act...
Jose Mourinho: Will Real Madrid begin their Champions League campaign with a win against Inter?
Jose Mourinho begins his second Real Madrid spell in the Champions League against former club Inter Milan, 16 years after winning the trophy with Inter at the Bernabeu. Will he finally deliver European glory in Madrid?
French A.I. Start-Up Mistral Raises $3.5 Billion as Part of Strategy Shift
Mistral is trying to keep pace with American and Chinese rivals while offering customers a European alternative for artificial intelligence.
Thriston Lawrence rallies from 6 behind and beats Paul Casey in a playoff in Switzerland
Thriston Lawrence is a winner for the third time in five years at the European Masters. This one took a final-round 62 and four playoff holes to beat Paul Casey.
EU seeks to reassure a Trump-rattled Greenland with promise of a new partnership and investment
The European Union is promising Greenland a stronger partnership and hundreds of millions of euros in investment, wanting to reassure Greenland after U.S. President Donald Trump's threats to take control of the island.
Barcelona youngster could be handed minutes vs Feyenoord
An up-and-coming member of the attacking ranks at La Liga giants Barcelona could yet be afforded minutes off the bench in the club’s European season opener.This comes amid confirmation that Jesse Bi...
Banijay Entertainment Unveils Ambitious Pan-European Lifestyle Format with Vinted
London, 24 August 2026: Media and entertainment group, Banijay Entertainment, today announces Live Better for Less, an ambitious new pan-European