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Angus Taylor’s tough talk on migration puts politics over policy and risks feeding damaging stereotypes
If the opposition leader is serious about fixing the migration system, he should start by creating clearer pathways for people already contributing or stuck in limbo indefinitely
Brown’s National Labs Day spotlights collaboration in AI-enabled science
A daylong conference brought scientists from the Department of Energy’s National Laboratories to Brown to explore new collaborations and research pathways for faculty and students.
Scientists discover hidden fat-burning switch that could strengthen bones
Scientists at McGill University have uncovered a hidden molecular “switch” that turns on a powerful calorie-burning system in brown fat — the body’s heat-generating fat linked to metabolism and weight control. The breakthrough centers on glycerol, a molecule released when fat is broken down in the cold, which activates an enzyme called TNAP and triggers an alternative heat-producing pathway that scientists had struggled to explain for years.
The Christ Hospital Health Network partners with universities to create new pathways for medical careers
The collaboration seeks to create new pathways for students to pursue medical careers while remaining in Ohio.
Food Frontier and IIFH partner to commercialize nutrition science innovations
The Innovation Institute for Food & Health (IIFH) at the University of California (UC) Davis, US, and Food Frontier are collaborating to advance scientific discovery by integrating it with agricultural production, culinary influence, and market execution. The partners aim to “activate pathways” bringing these innovations into restaurants, supply chains, and consumer markets, where they say adoption is ultimately determined. Specifically, they will build an infrastructure model to accelerate timelines, reduce risk, and unlock new growth opportunities for these new innovations. This platform will help develop, validate, and scale ideas in real-world conditions.
Stockton and AtlantiCare to Expand Health Education and Workforce Pathways
Agreement creates Stockton-AtlantiCare College of Community Health in A.C.
A Legacy of Care: How Pathways Behavioral Health Grew with West Tennessee
We're trusted with the health and wellbeing of more than half a million people living across 9,000 square miles of West Tennessee.
Seton Hall and TCNJ Partner on Graduate Health Pathways
Seton Hall and TCNJ introduce streamlined pathways into graduate programs in physical therapy, occupational therapy and athletic training.
Science gets closer to understanding how a psychedelic trip changes the brain
The small study found evidence that a single trip may alter pathways between parts of the brain responsible for emotional regulation.
Science gets closer to understanding how a psychedelic trip changes the brain
The small study found evidence that a single trip may alter pathways between parts of the brain responsible for emotional regulation.
AI lets chemists design molecules by simply describing them
Creating complex molecules usually requires years of experience and countless decisions, but a new AI system is changing that. Synthegy lets chemists guide synthesis and reaction planning using simple language, while powerful algorithms generate and evaluate possible solutions. The AI doesn’t just compute—it reasons, scoring pathways and explaining which ones make the most sense.
Scientists Discover Evolution’s 120-Million-Year-Old “Cheat Sheet”
A long-standing assumption about evolution is being challenged by new research showing that vastly different species can rely on the same genetic pathways to develop similar traits.
How employer partnerships are reshaping Chicago’s workforce
WGU explores how Chicago employers are investing in flexible education pathways to strengthen talent pipelines.
Global Health & WASH: May 2026 Funding Opportunities (14 new opportunities!)
The May update for Global Health & WASH brings new calls that cluster around three distinct shifts: LMIC research leadership moving from funder encouragement into a hard eligibility constraint, pharmaceutical and corporate-linked funders running structurally independent education and use-inspired research portfolios at substantial scale, and AI adoption shifting decisively from speculative tool to operational capability across health and WASH systems alike. In LMIC Research Leadership as Eligibility, Not Encouragement, Wellcome anchors the dominant signal of the month with three separate major calls that all require or strongly center LMIC leadership in their basic eligibility architecture. Wellcome’s ESIC Hubs (£1.5-£1.9M per hub over 3-5 years) explicitly requires an LMIC-based lead applicant, treating Global South leadership as a design constraint rather than a participation goal. Wellcome’s Infectious Disease Clinical Trial Development Award funds transdisciplinary teams whose lead must be a mid-career or established researcher based at an organization in Africa, South Asia, or Southeast Asia. Wellcome’s larger Infectious Disease Clinical Trial Award (£1M-£8M for optimizing licensed interventions) requires the administering organization to be in eligible LMIC regions and at least 50% of applicants based there. Around Wellcome, the same pattern shows up at smaller scale and across funders: CHINNOVA channels $1M into West and Central African research institutions for climate-health work; IBRO’s Neuroscience Training Grants explicitly tier ceilings by region of residence with Africa receiving the highest amount ($5,000); IHME’s GBD Emerging Researcher Award reserves at least one of its two annual awards for an LMIC researcher; Sidaction’s HIV Cure call funds research teams across France, the Netherlands, and eligible African countries with a minimum two-country collaboration requirement. Taken together, these calls signal a meaningful shift in how research equity is being operationalized — not as encouragement language at the bottom of a call, but as a structural feature of who can lead, where the work must be administered, and what proportion of the team must be regionally rooted. In Pharma-Funded Independent Medical Education and Use-Inspired Research, the lineup this month is unusually deep. Pfizer alone runs four parallel calls under independent education and quality improvement frameworks: a Migraine and Women’s Health RFP (200K x 2-year, $500K pool), Migraine IME ($200K, $1M pool), JAK Inhibitor evidence-based education ($100K), and Maternal Vaccination HCP Education in Saudi Arabia ($75K), plus a separate Pediatric Pneumococcal Surveillance research call in Saudi Arabia ($400K per project). Novo Nordisk Foundation runs four parallel calls of its own at substantial scale: Infectious Diseases Catalyst Grants (DKK 60M pool, up to DKK 7M collaborative), Non-Diabetic Endocrinology Collaborative Grants (DKK 53M pool, DKK 5-10M per project), Pioneer Innovator Grant Health (DKK 1.1M), and Distinguished Innovator Grant Health (DKK 6.8M). LEO Foundation deploys DKK 2-4M per project for dermatology research excellence. Pfizer’s framing across calls deliberately separates the funding from product promotion, emphasizing measurable practice-relevant change and structural distance between scientific outputs and commercial activity. Novo Nordisk’s “use-inspired” hard filter pushes researchers toward a credible translation pathway from mechanism to deployable tool. The pattern: industry-aligned funders are running structurally independent portfolios at meaningful $ that fund implementation evidence, not promotion. In AI as Operational Capability, Not Speculation, several calls this month explicitly treat AI adoption as a near-term operational question with real evidence and governance requirements, rather than a speculative trend to be watched. Wellcome’s ESIC Hubs frames AI as “the accelerator” for evidence synthesis, asking hubs to translate technical innovation into adoption-ready workflows that can match real-world policy timelines. UNICEF Venture Fund’s new Climate Tech for Children’s Health call funds for-profit startups deploying AI, machine learning, and blockchain in low-resource environments, with a strict requirement that solutions must already have a working prototype with promising pilot results. The Water Research Foundation has launched two simultaneous AI calls treating reproducibility, cybersecurity guardrails, and human-in-the-loop deployments as core design constraints rather than nice-to-haves: one on GenAI and Agentic AI in water utilities ($200K), one on alternatives to water shutoffs that explicitly screens for implementation economics evidence. Nordic Innovation’s quantum technology call (NOK 4.5M) extends the same logic into life science and healthcare, demanding consortium-stage projects mature enough to test with real users. TEF-Health offers €300K in subsidized testing infrastructure for European healthcare AI and robotics SMEs. The pattern: funders are converting AI pilots into playbooks, requiring transfer evidence and risk controls before AI can move from experimentation to sector-wide operational practice. For LMIC-based researchers in infectious disease or evidence synthesis, the three Wellcome calls together represent the deepest concentration of LMIC-led research capital in recent memory — pair the Infectious Disease Clinical Trial Development Award (£200K, deadline May 19) as a strategic pipeline feeder into the larger Infectious Disease Clinical Trial Award (£1-£8M, deadline June 2), since the development award functions explicitly as a track into the larger trial scheme. For Nordic researchers, the four Novo Nordisk Foundation calls plus LEO Foundation and Nordic Innovation Quantum represent ~$30M in regional research capital this cycle, all with deadlines clustered in May-August. For WASH practitioners, the three Water Research Foundation calls together (each up to $200K) are a cluster worth reading across — one on AI deployment, one on shutoff alternatives, one rewarding applied innovation — and the strongest applicants will articulate how their work bridges utility operations to policy-relevant evidence. For US-based clinical researchers and educators, the four Pfizer calls plus the APF Portfolio’s 80+ programs form an unusually accessible recurring pipeline; APF’s prohibition on indirect costs is a meaningful structural feature for early-career applicants whose institutions might otherwise absorb significant overhead. Snapshot of New Opportunities Total Estimated Funding Pool: $100 Million+ USD The grants are organized into three categories: Open Calls: Current grant and opportunities with a deadline. Grants are listed by closing date. 39 open opportunities- 14 new! Rolling Applications: current grant and opportunities with rolling applications (but it’s still best to submit as early as possible). 14 rolling opportunities- 1 new opportunity! Long term planning: Grants that have closed their current rounds, but are expected to open new windows. 4 long term opportunities! A quick tip for returning readers: if you want to jump straight to the newest additions, use CTRL F to search for “New!” and navigate quickly to the latest funding opportunities This post is for paid subscribers. This helps support the time and effort it takes to curate and organize these opportunities. Subscribe To keep this accessible to everyone who needs it, we’re happy to offer pay what you can rates. You can find more details here. Open Calls: Migraine Competitive Grant Program: Migraine and Women’s Health (Quality Improvement and/or Research RFP), Pfizer.*Closing soon!* Pfizer, in collaboration with the American Headache Society, is seeking independent quality improvement and research projects that close persistent gaps in migraine care for women across the United States. The funding logic centers on measurable, practice-relevant change: proposals should generate actionable evidence, tools, or system improvements that can be shared and used widely, not just within a single site. Priority areas span menstrual migraine and screening in women’s health settings, the role of hormonal fluctuations across the lifespan, sex-specific risk factors, comorbidities and quality-of-life burden, and disparities in outcomes by race, ethnicity, and socioeconomic status. The call is structured as a two-step competitive process with an initial Letter of Intent, with the strongest concepts expected to translate scientific insight into implementable improvements in diagnosis, management, and equity. Geographies: United States. Who can apply: U.S.-based organizations (not individuals), including professional schools, healthcare institutions, professional organizations, and other entities focused on healthcare improvement. Funding amount: Up to USD $200,000 total over 2 years; total pool USD $500,000. Targeted Sectors / SDGs: Health; Focus areas: migraine, women’s health, quality improvement, clinical research, menstrual migraine, health disparities. Deadline: LOI: May 5, 2026; Full proposal (by invitation): August 28, 2026. Learn more and apply here. This RFP rewards “shareable impact”: the most competitive submissions will pair rigorous methods with a clear plan for system uptake and dissemination beyond the originating institution. ReSSARC: Strengthening the Health Sector and Food Security in the Central African Republic (AID 013381/01/0) Call for Proposals, Italian Agency for Development Cooperation (AICS). *Closing soon!* AICS is seeking a limited set of high-capacity humanitarian partners to deliver an integrated package that stabilizes essential health services while reducing acute malnutrition and strengthening food security resilience in priority areas of the Central African Republic. The funder’s logic is explicitly nexus-based: proposals should meet urgent, life-saving needs while reinforcing local systems, coordination mechanisms, and community-level capacity so results persist beyond the emergency window. AICS emphasizes inclusion and protection outcomes, expecting gender-sensitive design and explicit measures for groups facing compounded vulnerability, including women, children under five, internally displaced people, and people with disabilities. The call also signals a localization pathway, encouraging stronger collaboration with national NGOs and balanced partnerships, alongside clear coordination with existing cluster and humanitarian actors to minimize duplication and improve coverage. Geographies: Central African Republic (Bangui, Ombella-Mpoko, Ouham, Ouham-Pende, Lim-Pende, Lobaye). Who can apply: Non-profit organizations registered with AICS, plus eligible non-profits without an office in Italy that have a pre-existing collaboration agreement with an AICS-listed organization. Funding amount: Total pool EUR €1,800,000; max EUR €800,000 (single applicant) or EUR €1,000,000 (ATS). Targeted Sectors / SDGs: Health; Focus areas: malnutrition prevention and treatment, maternal and child health, community health services, food security and resilience, localization partnerships Deadline: May 5, 2026. Learn more and apply here. This call is structured to reward partners who can link frontline service delivery to system durability and localization, not just short-term coverage gains. Contracts for Innovation in drug and alcohol addiction healthcare, Innovate UK. *Closing soon!* Innovate UK, on behalf of the Office for Life Sciences Addiction Healthcare Goals program, is procuring R&D to accelerate innovations that can improve treatment outcomes, strengthen recovery, and reduce harm and deaths linked to drug and alcohol addiction. The competition is positioned as a market-facing readiness push: selected projects are expected to advance solutions toward later-stage validation, generate evidence of user acceptability and UK market fit, and map credible routes through regulatory and certification requirements. Innovate UK signals a preference for innovations that can be field-tested in relevant UK settings and progressed to TRL 6 or 7, with practical plans for commercialization after contract completion. This structure favors applicants that can execute most work in-house, co-develop with service providers and people with lived experience, and translate technical progress into deployable tools for addiction healthcare delivery. Geographies: United Kingdom. Who can apply: Single organizations of any size (including EU, EEA, or international) leading delivery, with most work and key deliverables carried out in the UK; subcontractors for specialist skills only. Funding amount: GBP £200,000–1.5 million per project (inclusive of VAT); Total pool: GBP £20 million (across two strands). Targeted Sectors / SDGs: Health; Focus areas: Mental Health, Health Systems Strengthening, Research & Development, Technology Access. Deadline: May 6, 2026 (11:00am). Learn more and apply here. This call uses procurement to pull near-market addiction innovations toward operational proof and adoption pathways in UK services.
Empowering Veterans: The 2026 Fayetteville Veterans Business Expo aims to close the opportunity gap
This is the first year of the Veteran Business Expo, and it grew out of Fayetteville PWC’s Economic Impact Program, which focuses on expanding access and opportunity in public-sector contracting while strengthening the local economy. It builds off the success of previous events held by PWC, like the 2024 Industry Day (pictured above). Photo provided by PWC. The Fayetteville Public Works Commission (PWC) will host the inaugural 2026 Veterans Business Expo on May 14 at the PWC Main Operations Complex at 955 Old Wilmington Road, seeking to connect former U.S. Military members with vital business opportunities in their community. The event, which will take place from 4 p.m. to 6 p.m., is part of a partnership between PWC and the Veterans Business Outreach Center at Fayetteville State University (VBOC) and Fayetteville-Cumberland Regional Entrepreneur and Business HUB (FSU HUB).Aaron Harris, PWC’s manager of economic inclusion programs, said the event is designed to connect Veteran-owned businesses with partners and decision-makers who can help move opportunities forward.“This event brings together Veteran entrepreneurs alongside government agencies, public entities, contractors and resource partners in one place, creating a purposeful space to build relationships, exploring procurement and contracting possibilities and strengthening our region’s Veteran-owned business community,” Harris said. The Veterans Business Expo was devised to feature, highlight and facilitate direct connections and commerce. “We want to get our Veterans a platform for their businesses,” said Camille Little, the supplier diversity analyst at PWC. “Here at PWC, we have 20 departments, and we procure… I can’t tell you all the goods and services. This is our first expo. We’re looking for general contractors, electricians, landscapers, janitorial, construction suppliers, architecture, farms and engineering firms.” Little said, much like businesses in every industry, Veterans are often in need of assistance getting their foot in the door.“When Veterans are starting up, they have to know what resources are [available],” Little noted. “They have this ample amount of resources, but they need to know how to get started.” Identifying those resources and connecting Veteran business owners with opportunities and business development programs are made possible by the partnership between PWC and VBOC, Little said. The partnership has allowed the expo to flourish, she added.“There are opportunities, there are consultant workshops and different things that we partner with them for all the time,” Little said. “It’s about easing that transition because starting a business is hard. Having the dedication to continue after that first year is even harder right now.” That is why, Little said, the partnership with resources from Fayetteville State University brings decision makers to the table. “If you are a Veteran business owner, you may not know how to do business with PWC or the City of Fayetteville or FSU, or partners,” Little said. “‘Where do I get started?’ ‘How do I get contracts?’ Bringing people to an understanding and then having an opportunity like this, where you’re talking to that person who’s making the decision… that is our goal.”Those meetings between Veteran-owned businesses and other decision-makers will present a chance to showcase products and services directly to organizations seeking qualified vendors and capable partners, Harris said. Agencies and contractors, he added, can meet and engage businesses ready to support upcoming needs. Little said PWC and all of its departments, as well as the City of Fayetteville, and FSU will be on hand. Additionally, there will be procurement officers from the North Carolina Department of Public Safety. “Resource partners who support small business development will also be on hand, helping make introductions and reinforcing pathways that support growth for Veteran entrepreneurs,” Harris said.For Veteran entrepreneurs, Little said she recommends two things: an answer to “why?” and a business plan.“I would ask them, what problem are they solving with their business?” she noted. “Then I would also tell them to start making a business plan. I run into a lot of firms, and it’s like, ‘What is your plan?’ So just knowing where you want to go with your business is important.”Little said it is important to differentiate between a business that helps transition servicemembers away from the U.S. Military versus a business that Veterans consider the next chapter of their lives.“How much dedication are you going to give to this business to make it successful?” Little noted. “So I would always start with what’s your business plan.”For Harris, the event will be able to cover the needs of all types of Veteran-owned businesses.“Another important lesson is the need to meet businesses where they are,” he said. “Veteran-owned businesses are at different stages of development, so offering multiple entry points, networking, education and referrals has proven essential.”Registration information can be found at: www.eventbrite. com/e/2026-veterans-business-expo-connecting-heroes-to-opportunity-tickets-1984308563329?aff=ebdssbdestsearch
Scientists just discovered what coffee is really doing to your gut and brain
Coffee doesn’t just energize—it actively reshapes the gut and mind. Researchers found that both caffeinated and decaf coffee altered gut bacteria in ways linked to better mood and lower stress. Decaf even improved learning and memory, while caffeine boosted focus and reduced anxiety. Together, they show coffee works through multiple pathways beyond just caffeine.
Scientists just discovered what coffee is really doing to your gut and brain
Coffee doesn’t just energize—it actively reshapes the gut and mind. Researchers found that both caffeinated and decaf coffee altered gut bacteria in ways linked to better mood and lower stress. Decaf even improved learning and memory, while caffeine boosted focus and reduced anxiety. Together, they show coffee works through multiple pathways beyond just caffeine.
‘The reality, for better or worse’: Columbia comp sci students and faculty grapple with AI’s disruption of the field
‘The reality, for better or worse’: Columbia comp sci students and faculty grapple with AI’s disruption of the field ‘The reality, for better or worse’: Columbia comp sci students and faculty grapple with AI’s disruption of the field A field that once seemed like a direct path to stable, lucrative work is becoming less certain under AI, students and faculty told Spectator. By Ria Vasishtha and Arjun Menon May 3, 2026 Shanying Liu / Deputy Illustrations Editor Asia Genawi, SEAS ’29, first encountered artificial intelligence during her sophomore year at her high school in Indiana. Back in 2023, policies on AI varied widely—even within the same district—and some schools had no guidance at all. As Genawi began to see the effects of AI trickle into her classroom, she turned to guidance from her home state’s Department of Education, which she said she found “outdated and inaccessible.” Genawi spent the rest of her high school career dedicated to the issue, including writing a 15-page memo exploring varying AI policies across Indiana schools, which she sent to every Indiana state senator and representative whose contact information she was able to find. She later helped draft a bill that would have required public high schools to establish and share their own AI policies with students in an accessible format. But with so many other bills already awaiting referral, hers never made it to committee. When Genawi arrived at Columbia to study computer science, she found that the gaps she had spent years trying to address in Indiana had followed her there. Many students and professors were also grappling with what AI meant for the field. Across Columbia’s undergraduate schools, computer science has become the most popular major—accounting for around 11 percent of degrees awarded in Columbia College, 32 percent in the School of Engineering and Applied Science, and 12 percent in the School of General Studies in 2024. While the number of computer science majors in SEAS grew from 166 to 173 during the 2024-25 academic year, the total number across the three schools fell around 4.5 percent from 393 to 375, driven by declines at Columbia College and General Studies. At Barnard, it has grown to become the second most popular major as of 2025, up from third the year prior. The number of degrees awarded have grown fivefold since 2016. Faculty members and students in the department told Spectator that the surge in the major’s popularity has been driven in large part by its apparent promise of a secure, well-paid career path. However, they noted that the recent rise of generative AI has compromised the sense of stability that once defined the field, even as interest in technical skills among students persists. According to data from the Federal Reserve Bank of New York in 2024, out of 74 majors tracked, computer science had the fifth highest unemployment rate among majors at 7 percent, while computer engineering had the second highest at 7.8 percent. “Anecdotally, people are moving away from CS as a major,” Daniel Bauer, a senior lecturer in the computer science department, said. “They’re still taking some of our classes, right, because they think they need that, but they’re instead majoring in other things.” Bauer described a field that had shifted from what he called a “nerdy outlier discipline” to one that “everyone needs,” a sign that technical skills have become a baseline expectation across industries with the emergence of AI. “A lot of people thought, ‘Oh, it’s a guaranteed path to a stable income. You get a six-figure job right out of your undergrad,’” Bauer said. Now, companies may see AI as a way to reduce demand for entry-level programmers, especially in what he calls “code monkey jobs,” roles where a large number of employees are “just writing out code nine-to-five.” Chris Murphy, a senior lecturer in the computer science department, described the current moment as the convergence of two forces: the downturn of the job market and generative AI coming onto the scene. “Things kind of started to really pick up in 2014, 16,” he said, recalling the years after the weaker 2010 market. Murphy added that this was also a period where “students were getting more experience outside of class than they were inside of class” through internships, jobs, and side projects. Murphy suggested that the earlier momentum helped make computer science feel like both an academic program and a reliable pathway into work. That feeling is harder to sustain now as the industry reconfigures, which is a shift that students are seeing firsthand. Rebecca Yu, SEAS ’27, said that during a recent internship in Big Tech, she saw that “every single tech company was racing to integrate” large language models. She added that her manager said her intern class was the first to complete their assigned projects, which she attributed to the increased efficiency that comes with AI. Frank Liu, SEAS ’29, said that with AI lowering the barrier to coding, companies now expect everyone to write code. “A lot of companies outright say if you’re not using coding in your job, you might get fired for not being productive enough,” Liu said. Yu similarly expressed that students increasingly have to accept AI being a part of industry workflow, adding that many also “make use of it to maximize their productivity.” Richard Li, CC ’28, described a “franticness” among his peers as the pace of change accelerates. He explained how “some new tool” is released regularly, noting that tools rise and fall in prominence within weeks. He has come to believe that he doesn’t need to “match that speed all the time” and keep up with every development. Li has learned that AI tools allow him to “take a breath” and “get back into the loop much easier than before” when he needs to. While some companies specifically target Columbia when hiring, sending representatives to campus career fairs and recruiting large numbers from Columbia, a computer science degree cannot be treated as a static credential, Yu described. “You can’t just get your degree and stop learning after that. You have to always be learning,” Yu said. “That is something you basically have to expect for your job.” AI has not only affected students’ decisions to major in computer science, but also reshaped how the subject is taught. Across departments, faculty members no longer treat work done outside the classroom as a reliable measure of understanding, shifting instead toward in-person exams, quizzes, and attendance checks. While homework once made up as much as 60 to 70 percent of a student’s grade in computer science classes, Murphy said that breakdown has since flipped, with exams and quizzes now accounting for the majority. “The assumption—especially among pessimists—is that they’re using it to do their homework,” Murphy said. “They take the homework assignment. They put it into generative AI. Out comes the solution. Submit solution. The end.” Murphy said that faculty members ranged in their responses from fully prohibiting AI use to actively teaching students how to effectively work with AI. He said he shifted his approach this year after his teaching assistants called his belief that students weren’t using the technology “naïve,” and now permits students to use AI on assignments. His surveys of students in his introductory classes have told a more complicated story than the one so-called pessimists offer: Around 60 to 70 percent of students who reported using AI said they used it to have concepts explained to them, to clarify assignment instructions, to generate test cases, or to create practice questions. “Those are all ways that you might have had a tutor in the past to do that, and now you have this AI essentially as your tutor,” he said. Bauer has taken a different approach, teaching students how to use AI productively without sacrificing the core principles of the discipline. “People who are trained to actually use AI tools productively, while being in charge of designing the overall project, will be very much in demand in the next couple of years,” he said. Over the past year, a working group of computer science faculty has been redesigning the introductory and intermediate programming sequence to integrate generative AI as both a subject and a tool, representatives from SEAS wrote in a statement to Spectator. The effort is “coordinated” across the department, “not course-by-course,” with a systematic assessment of how AI integration is affecting student outcomes underway to shape the next round of changes. The goal, the department explained, is for students to be able to “read, verify, and reason about code, whether they or a model wrote it.” Tony Dear, senior lecturer in the computer science department, is piloting individualized AI feedback in a discrete mathematics course, while a machine learning course is also testing a Socratic AI dialogue system designed to “guide inquiry rather than supply answers,” the statement reads. Beyond individual courses, SEAS funded seven cross-departmental faculty projects in generative AI this past academic year, spanning biomedical engineering, chemical engineering, industrial engineering, and computer science, according to the statement. This phenomenon extends beyond the computer science department. SEAS’ new AI minor, which it announced in November 2025, reflects the University’s attempt to adapt. The minor is specifically designed for noncomputer science majors and aims to provide “essential AI knowledge” while emphasizing practical and responsible use across disciplines, according to the SEAS website. At the center of the minor is AI in Context, a course taught by a team of faculty from the departments of computer science, applied mathematics, philosophy, music, literature, and the Writing Center, the representatives told Spectator. Bauer described it as targeted at students who want to bring AI into fields like economics or biology, rather than as a path into software engineering itself. At the graduate level, SEAS announced a new Master of Science in artificial intelligence in February, with the inaugural cohort starting in the fall. While recognizing how AI has helped them navigate coursework, students also described its rise as isolating, even among members of the Application Development Initiative, one of Columbia’s largest computer science clubs. “As people start to ask AI for questions that they would normally ask students and members, it starts to isolate people” Li said. Alexa Kafka, BC ’27, echoed Li’s sentiment, pointing out that computer science has always been a collaborative discipline with code reviews and pull requests, even as AI makes independent work easier. Despite this, Kafka noted that she hasn’t been to office hours “in at least a year.” Bauer added that faculty are exploring long-term solutions to the assessment problem. “One of the things that we’re trying to do at the department or school level is to maybe move towards computerized testing facilities,” Bauer said, referring to ideas in the department to revitalize computer labs as an alternative to pen-and-paper exams. “We have to accept that this is the reality, for better or worse.” But more exams, students say, does not mean better learning, nor does it reflect how computer science is actually done. “Code is so variable and can be approached in so many directions, there’s never just going to be one correct answer. There can be multiple optimal solutions,” Kafka said. Students also expressed concern that the shift toward exam-heavy grading pulls focus away from the applied, project-based work that better reflects both discipline and industry expectations. ADI has tried to respond more quickly than the curriculum can. Through a vibe coding workshop this past semester, club members said they wanted to help students understand not just that AI exists, but how to use it deliberately. “Vibe coding” refers to the practice of prompting AI to write code for a task or project, and has become widespread enough that ADI felt the gap in formal instruction was worth addressing, according to Sophia Huang, BC ’29. The workshop introduced students to the concept of context engineering, which Shaina Sahu, SEAS ’27, described as not just writing a prompt, but optimizing “the rest of the relevant information that you would feed into the model.” Without that, students said that AI-generated code can fail at scale or introduce difficult-to-detect bugs. Genawi said the shift toward AI has changed what it means to be good at computer science. “I think the shift has kind of gone towards what can you create and what can you do, instead of, what do you know,” she said. Indeed, during ADI DevFest, its annual hackathon, Li said more teams are trying to complete their projects than in years past. While sign-ups have historically outpaced submissions, Li said this is beginning to change because teams “have a tool that completes the vision for them.” While many students see AI as an equalizer that lowers the barrier to entry for coding and technical work, Murphy said it also creates new equity concerns inside the classroom around who can afford stronger tools and who already knows how to use them. “The equity issues I worry about are students who have access to paid versions of things versus free versions of things,” he said. Although popular AI models like ChatGPT and Claude have free versions available, both have paid models that can reach over $100 per month, which output different qualities of code. Murphy also pointed to differences in prior exposure to AI literacy itself. “Students who go to high schools or K-12 education, where they’re taught AI literacy, prompt engineering, context engineering, they understand how to do this, as opposed to students who go to schools who don’t teach that,” he said. “Then they come in, and then they’re somehow expected to know how to use these tools.” For Genawi, those disparities begin long before students arrive on campus. “It’s very interesting to consider how lucky you were geographically,” she said. “To be born where you were is influencing your ability to get access to these spaces.” Students like Yu, though broadly apprehensive about the future of computer science, are not without hope. “I’m optimistic, because I think if you’re truly passionate about CS, there will definitely be a place in the field to do something you want to do,” she said. Senior Staff Writer Ria Vasishtha can be contacted at ria.vasishtha@columbiaspectator.com. Follow Spectator on X @ColumbiaSpec. Staff Writer Arjun Menon can be contacted at arjun.menon@columbiaspectator.com. Follow Spectator on X @ColumbiaSpec. Want to keep up with breaking news? Subscribe to our email newsletter and like Spectator on Facebook. Produced with Spectate by Emily Ta
Health Professions and ZagsConnect
Gonzaga Health Professions Pathways and ZagsConnect
Scientists may have found the brain’s switch for chronic pain
Deep within the brain, scientists have uncovered a hidden “switch” that may decide whether pain fades away—or lingers for months or even years. Researchers found that a small, little-known region called the caudal granular insular cortex (CGIC) acts like a command center, telling the body to keep pain signals alive long after an injury has healed. In animal studies, shutting down this pathway not only prevented chronic pain from forming but could even erase it once it had taken hold.
Middle, High School Students Given a Spark to Explore Pathway into Science at Mission College
To connect middle and high school students to a possible career in science, El Nido Family Centers partnered with Bioscience Los Angeles County Inc. (Bioscience LA) and LA Mission College […]
CBL Scholars Program Opens Pathways to Business Law Careers - UC Law San Francisco (Formerly UC Hastings)
First-year law students and 2026 CBL Scholars Deniz Masjedi, Alvaro Flores, and Tavia Pappaly gain mentorship connections with leading industry professionals as they prepare for careers in business law. Created by the UC Center for Business Law San Francisco (CBL), the CBL Scholars Program aims to develop the next generation of business law leaders, supported by contributions from individuals and corporate sponsors. The highly competitive program provides funding along with academic and professional mentorship to students from disadvantaged backgrounds. Scholars gain exposure to the Bay Area’s technology and venture capital ecosystems and access to UC Law SF’s broad network of senior legal professionals. Now in its sixth year, the CBL Scholars Program provides a scholarship and academic and professional mentorship to students entering the business law community from disadvantaged educational, economic, social, or physical backgrounds. The program is generously sponsored by the law firms Gunderson Dettmer and Goodwin Procter. Meet this year’s CBL Scholars: Deniz Masjedi, Alvaro Flores, and Tavia Pappaly. All three have secured summer associate positions at prestigious law firms. Deniz Masjedi: A Passion for Helping Founders Grow Companies Deniz Masjedi, who was born in Iran and moved to Southern California as a teenager, traces her interest in law to her family’s immigration journey and her desire to advocate for herself and her family. She earned a bachelor’s degree at UC Berkeley, where she studied political science and sociology. At UC Law SF, she serves as a 1L representative for the Iranian Law Students Association and is active in the Business Law Society and Technology & Law Society. Next fall, she will serve as director of mentorship for the Technology & Law Society and director of professional development for the Business Law Society. She will join Sidley Austin this year as a 1L/2L summer associate. Q: What draws you to business law? A: Prior to law school, I worked in Cooley LLP’s Private Companies practice group as a corporate paralegal for three years, supporting over 100 venture-backed startups and venture capital funds. I found purpose in helping founders transform their vision into successful companies. It was incredibly rewarding being part of their journeys—from company formation and initial financing to major transactions such as M&A deals. What excites me most about this field is the potential for a small, innovative company to become the next Google or Zoom, shaping how people communicate and access information. I hope to continue supporting entrepreneurs and investors as a corporate attorney. Q: What does it mean to you to have been awarded this scholarship? A: As the first person in my family to attend law school in the United States, receiving this scholarship is a tremendous honor. My parents and I left everything behind so that I could enjoy the freedom to practice my religion without persecution and pursue a career in law as a woman. This award is an acknowledgment of my dedication to business law and motivates me to continue pursuing excellence in this field. It also recognizes years of hard work—learning a new language, navigating the college and law school application process, and ultimately building a career in the legal profession. Q: How will this scholarship help support your future goals? A: This scholarship will provide access to mentorship from leaders in the field, enabling me to develop the skills necessary to offer practical advice and effective representation to future clients. It also eases the financial burden of law school, letting me focus on my coursework and deepen my commitment to corporate law. As an immigrant, breaking into the legal profession has not always been easy, and the time that mentors have invested in me has been instrumental to my progress. This scholarship will allow me to continue building those relationships while positioning me to one day mentor others pursuing similar paths. Alvaro Flores: Inspired by Entrepreneurs The son of Mexican immigrants raised in San Antonio, Texas, Alvaro Flores says he has long been interested in how policy, markets, and culture shape society. He studied international relations and global economy at the University of Southern California, with minors in business finance and legal studies. His experiences span local political organizing, venture capital and startup work, and teaching entrepreneurship. At UC Law SF, he is involved in the Business Law Society, Technology & Law Society, and the Latinx Law Student Association. He will join Perkins Coie as a 1L/2L summer associate with the firm’s Emerging Companies & Venture Capital practice. Q: What draws you to business law? A: I’m drawn to stories of entrepreneurs whose simple ideas become companies that shape the economy and society. Spending time in venture capital and working directly with founders has shown me that many important decisions in the scaling process are ultimately legal ones, particularly how companies are structured and how capital is raised. Business law sits at the intersection of innovation and equity. It offers a way to stay close to the pace of technological change while also helping expand who gets to participate in it. There is something special about being part of that process here in the Bay Area, where the American Dream feels like it is reimagined in real time. Q: What does it mean to you to have been awarded this scholarship? A: I am truly grateful for the support and belief this scholarship represents. I see it not just as recognition, but also as alignment. The CBL Scholars Program’s focus on developing individuals who engage deeply with the business and technology ecosystem reflects the path I have been intentionally building. More than anything, it feels like an investment in that journey. I have been thoughtful about each next step–whether teaching, working in venture capital, or building multidisciplinary experiences–and this scholarship reinforces that those efforts come together in a meaningful way. Q: How will this scholarship help support your future goals? A: It allows me to focus more on developing as a business lawyer, without the distraction of financial constraints. Beyond that, the mentorship and access to the Bay Area network are just as valuable. I’m especially interested in working with early-stage companies and investors, so the opportunity to learn directly from people operating at a high level in that space is huge. Tavia Pappaly: Working in the Wine Industry Sparked Interest in Business and Law Tavia Pappaly spent five years in the wine industry before deciding to pursue law school with a goal of becoming a corporate transactions attorney. Pappaly says she wants to use her legal skills to help business grow and thrive. A first-generation law student from Fairfield, California, she is a member of the Legal Education Opportunity Program (LEOP) and will serve as vice president of social planning for the UC Law SF Sports Law Society in her 2L year. She plans to work as a summer associate at Gibson Dunn in San Francisco after her 2L year. Q: What draws you to business law? A: Business law brings together many of my interests and personal experiences. As the daughter of immigrants who grew up around a family-owned small business, I saw firsthand both the opportunities and challenges of building something from the ground up. That perspective, combined with my experience in the wine industry, solidified my interest in helping businesses of all sizes tackle evolving legal challenges. I’m excited to grow within the corporate law space and develop the skills and experience to support businesses at every stage. I’m deeply motivated to give back to immigrant communities and small business owners, whose experiences often intersect. By building a strong foundation in corporate law, I hope to support those working to create generational stability and to contribute in a meaningful way to the communities that have shaped me. Q: What does it mean to you to have been awarded this scholarship? A: Receiving this scholarship is incredibly meaningful to me. I take great pride in my background as a first-generation student and a woman of color, so being recognized for my potential in a field that has historically underrepresented those communities is both affirming and empowering. This program will help connect me to the resources and committed mentors that will help me succeed. Beyond that, it is no secret that law school is a significant financial commitment. This scholarship helps ease both the financial burden and the stress that comes with it, allowing me to focus more on my education and long-term goals. I am incredibly grateful! Q: How will this scholarship help support your future goals? A: This scholarship has already connected me with an incredible network of faculty, business law professionals, and like-minded students. The community fostered by the Center for Business Law is deeply supportive, and I’m excited to grow alongside my cohort. I truly believe this network will play an important role in helping me thrive in law school and position me for success in business law. As I have seen firsthand how impactful both financial scholarship and mentorship are, I hope to give back in this same way later in my career.
Carderock Scientists Inspire Future Innovators at Calvert County MESA Day
Naval Surface Warfare Center, Carderock Division (NSWCCD) representatives engaged with students in a rural Maryland community during the Calvert County MESA (Mathematics, Engineering, Science Achievement) Day at Huntingtown High School, April 9. Through an inspiring keynote speech and a live demonstration of a Boston Dynamics robot dog, Carderock scientists highlighted pathways to naval engineering careers, reinforcing the Navy's commitment to building the future STEM workforce by bridging the distance to underserved communities.
Mechanohealth: Where life science meets physical forces for health innovation
Integrating mechanobiological principles into disease pathogenesis, therapeutic development, and tissue engineering is reshaping our understanding of biological systems and accelerating the advancement of mechanotherapy and mechanohealth. This field reveals how mechanical cues regulate cellular behavior, such as force transmission along integrin-nucleus pathways and collective cell migration, and tissue functions. In doing so, mechanobiology connects fundamental research with clinical applications, from limiting cancer metastasis and fibrosis to promoting bone regeneration and maintaining vascular homeostasis. Building on discussion from the Inaugural International Conference on Mechanobiology (ICM) 2025, integrating mechanobiological research with clinical strategies offers new opportunities to address unmet needs, including personalized anti-fibrotic interventions or precision bone regenerative therapies. At the same time, it supports the broader concept of mechanohealth -- a paradigm focused on preserving the physiological mechanical balance within tissues.
Amid speculation about LIV Golf's future, PGA Tour CEO Brian Rolapp open to new pathways for players to return
Free small business financing, support workshop scheduled in Kailua-Kona
It is a valuable opportunity to learn about funding pathways and connect directly with experts who can support the next steps of small businesses; only several spaces remain, so don’t wait, register today.
Public Health Leadership Starts in the Classroom
Learn how states are integrating public health education into K-12 schools and building pathways for future public health professionals.
Healthcare Worker Making Heart Gesture.
LITTLE ROCK — The University of Arkansas for Medical Sciences (UAMS) and the University of Arkansas-Fort Smith (UAFS) have entered into a formal Memorandum of Agreement designed to create clear, accelerated pathways for UAFS graduates pursuing careers in health care. The agreement covers 14 UAMS programs across four colleges and…
AHSAA pathway to championship changes for fall, winter and spring sports
With the AHSAA public and private splits for championship play, the pathway to championships will look different.
Medicare may nix breakthrough device payment pathway
In this edition of STAT Health Tech: CMS may change breakthrough device payments, Zealthy's legal troubles, and more.
Seton Hall Students Gain Insight at Sports Medicine Conference
Seton Hall B.S. in Interprofessional Health Sciences students gained insight into career pathways, networked with professionals and connected classroom learning to practice.
Towards better vision: WHO South-East Asia regional meeting on eye health
The WHO South-East Asia Regional Meeting on Eye Health was convened to address the substantial and persistent burden of avoidable vision impairment in the Region. South-East Asia accountsfor nearly one third of the world’s blind and visually impaired population, with cataract, uncorrected refractive error, and diabetic retinopathy contributing to more than 90 percent of cases. The meeting responded to the need for coordinated action to achieve the 2030 global targets for effective cataract surgical coverage and effective refractive error coverage, and to advance implementation of the Regional Action Plan for Integrated People Centred Eye Care. It provided a platform for reviewing progress, identifying system gaps, and strengthening country pathways to accelerate universal access to quality eye care.
The Many Faces of STEM
UNLV graduate students host a science workshop at Sunrise Mountain High School, providing an opportunity for kids to explore numerous career pathways.
Simon Business School expands pathway to accelerated master’s degree through new college partnerships
Undergraduate students at partner institutions can earn their MS from the Simon Business School in one year.
Masters 2026: Only one question remains for Rory McIlroy — how high will he climb among golf's all-time greats?
McIlroy may never have the numbers to catch Jack Nicklaus or Tiger Woods, but he certainly has a pathway to No. 3 all-time.
Science students find mentorship and pathways to career success
Batool Abdulruhman and Alyssa Rivera both grew up in rural Valley communities where doctors are scarce and medical care is difficult to access. Now they are on a path to become doctors practicing in the Valley because of the support and mentorship they received through the Center for Access to Science for All (CASA) in […]
Scientists just found a hidden “drain” inside the human brain
A hidden waste-removal pathway in the brain has finally been caught in action. Using cutting-edge MRI scans, researchers discovered that fluid flows along the middle meningeal artery in a slow, lymphatic-like pattern—very different from blood. This confirms the presence of a previously unknown drainage hub in humans. The finding could transform how scientists approach brain aging, injury, and diseases like Alzheimer’s.
Scientists discover spice synergy that boosts anti-inflammation 100x
Chronic inflammation often works quietly in the background but can fuel serious diseases like diabetes, heart disease, and cancer. New research reveals that everyday plant compounds—like menthol from mint, cineole from eucalyptus, and capsaicin from chili peppers—can team up inside immune cells to dramatically boost their anti-inflammatory power. While individual compounds showed modest effects, certain combinations amplified results hundreds of times over by activating different cellular pathways at once.
Scientists discover spice synergy that boosts anti-inflammation 100x
Chronic inflammation often works quietly in the background but can fuel serious diseases like diabetes, heart disease, and cancer. New research reveals that everyday plant compounds—like menthol from mint, cineole from eucalyptus, and capsaicin from chili peppers—can team up inside immune cells to dramatically boost their anti-inflammatory power. While individual compounds showed modest effects, certain combinations amplified results hundreds of times over by activating different cellular pathways at once.
What Is Tmrw Longevity Powder? Here's what to know about the blue scoop
Tmrw Longevity Powder combines blue spirulina with a focused blend designed to support energy, clarity, digestion and healthy aging pathways.
Community event to celebrate history through the lens of sports
This Saturday, the historic Carver Recreation Center in Charlottesville will host the Black History Pathway event.
NovaBridge Reports Full Year 2025 Financial Results and Provides Business Update
Successful transformation to global biotech platform with two mid-stage potential best-in-class/first-in-class programs, givastomig and VIS-101, with compelling proof-of-concept dataGivastomig, a potential best-in-class/first-in-class Claudin 18.2-directed bispecific antibody for gastric cancer, has shown robust and durable responses with broad CLDN18.2 activity, favorable safety, as well as potential eligibility for FDA’s Accelerated Approval Pathway with potential initiation of a registrationa
Scientists discover hidden brain switch that tells you to stop eating
Your brain’s “stop eating” signal may come from an unexpected source. Researchers found that astrocytes—once thought to just support neurons—actually play a key role in controlling appetite. After a meal, glucose triggers tanycytes, which send signals to astrocytes that then activate fullness neurons. This newly discovered pathway could lead to innovative treatments for obesity and eating disorders.
New Mexico's court-mandated pathways to mental health care
Lawmakers have made changes in recent years to bolster the treatment system, but advocates say wide gaps render them insufficient.
Preparing the Next Generation of Alcohol and Drug Counselors
UNO’s Clinical Mental Health Counseling program is expanding its reach and impact by offering students a pathway to dual licensure in both mental health and substance use counseling. In just two additional courses beyond their required coursework, students can become eligible for Nebraska’s Provisional Licensed Alcohol and Drug Counselor (PLADC) credential.
A gene mutation may trap the brain in the wrong reality in schizophrenia patients
A newly identified gene mutation may help explain why schizophrenia patients struggle to update their understanding of reality. The mutation disrupts a brain circuit involved in flexible decision-making, causing mice to stick with outdated choices even when conditions change. Researchers pinpointed the issue to a key thalamus–prefrontal cortex pathway. By reactivating this circuit, they were able to restore normal behavior—raising hope for future therapies.
Two Maine universities launch program to boost health care workforce
The joint program offers a fully online pathway from medical laboratory technician to medical laboratory science and the state’s only bachelor’s degree in this field.
Club sports serve as a pathway to varsity level athletics
While club and varsity sports operate as independent units, participants are all athletes on one campus. As a Division III school, opportunities arise for club athletes to play on a bigger field, and vice versa. For senior lacrosse goalkeeper Nichole Allan, the chance did not come until her final semester at Ithaca College.
Researchers lead push for health innovation at NextGen Pathways Symposium
Missouri S&T researchers joined colleagues from across the University of Missouri System at the Havener Center March 12-13 to share the latest developments from projects that could improve health outcomes for the state and beyond.
McPherson College and Barton School of Business at Wichita State Launch Accelerated MBA Pathway Partnership
Wichita State University’s W. Frank Barton School of Business and McPherson College have announced a new academic partnership that will allow eligible
UAB’s Nurse-Midwifery Pathway receives accreditation, a step forward for women’s health in Alabama
UAB’s Nurse-Midwifery Pathway receives accreditation, a step forward for women’s health in Alabama
📸 They played for two countries… and everyone forgot!
In modern football, international pathways are no longer always linear. Some players first wear one national team’s shirt at youth level before choosing another when stepping up to senior level.Othe...
With stricter laws across the Southeast, NC remains an access point for abortion care
Out-of-state patients got more than one-third of the abortions provided in North Carolina in 2025, as telehealth expands as a pathway to care.
“Self-Determination is the Pathway to Liberation”
The 66-page report, “‘Self-Determination is the Pathway to Liberation’: Alternative Mental Health Crisis Response in the United States,” identifies key elements of rights-respecting responses to mental health crises and explores how alternative mental health crisis response programs have carried out these approaches in practice. Many of these models share core elements, including promoting individual autonomy, providing voluntary support rather than mandating compliance, and avoiding unnecessary law enforcement involvement.
2026 NFL Offseason: International Player Pathway Program Pro Day
2026 NFL Offseason: International Player Pathway Program Pro Day | @EdEastonJr
Vanderbilt Lung Transplant Program sets new record
The Vanderbilt Transplant Center is now the second largest lung transplant center in the United States by volume, with 149 lung transplants in 2025, the most ever in one year at Vanderbilt Health. The Vanderbilt Lung Transplant Program leads the nation in organ preservation and regeneration and is among the best in long-term outcomes, demonstrating the success of the interdisciplinary team in caring for these complex patients. Several features make the program unique in the United States, said Konrad Hoetzenecker, MD, PhD, professor of Thoracic Surgery and surgical director of the Vanderbilt Lung Transplant Program. Vanderbilt serves as a “second opinion center” and accepts most complex candidates that are turned down by other centers due to increased perioperative risk. This includes patients over 70 years old, patients requiring combined procedures with their transplant, multiorgan transplantations and sensitized patients (individuals who have pre-formed anti-HLA antibodies who are at higher risk for complications). The expertise and excellent outcomes have attracted patients far beyond the borders of Tennessee; almost half of Vanderbilt Health’s lung transplant recipients come from out of state. “Another unique feature is our minimally invasive transplant program,” Hoetzenecker said. “By using distinct surgical instruments and techniques, the incisions can be kept as small as 7 to 8 centimeters, which results in better healing, less pain and faster recovery. “This minimally invasive approach is embedded in an Enhanced Recovery After Surgery (ERAS) protocol, a multimodal, evidence-based perioperative care pathway designed to reduce surgical stress, minimize complications and speed up recovery. Our unique ERAS protocol, by a dedicated interdisciplinary approach, aims to improve recovery after lung transplant and reduce ICU and hospital stay.” The lung transplant program recently celebrated a milestone — 1,000 lung transplants since the program began in 1990. “This significant achievement reflects the concerted effort of a multidisciplinary collaboration by the Departments of Thoracic Surgery, Medicine, Anesthesiology and Critical Care,” said David Erasmus, MD, associate professor of Medicine and medical director of Vanderbilt Lung Transplant. Lung transplants have been attempted since the 1960s, but they were largely unsuccessful until the 1980s, when surgical techniques were refined and new antirejection drugs proved effective. Patient outcomes steadily improved from the 1990s to the present. Vanderbilt’s fourth lung transplant recipient in 1990, Pam Everett, is the longest-living, single-lung transplant known in the world, recently celebrating 35 years since her transplant. The Vanderbilt Lung Transplant surgical team is led by Hoetzenecker and Caitlin Demarest, MD, PhD, the surgical director and associate surgical director of the Vanderbilt Lung Transplant program. Erasmus is the medical director of Vanderbilt Lung Transplant along with Anil Trindade, MD, associate medical director and associate professor of Medicine.
Scientists find gut bacteria inject proteins that control your immune system
Gut bacteria aren’t just passive passengers—they can actively send proteins straight into our cells. Using microscopic injection systems, even harmless microbes can influence immune responses and metabolic pathways. Researchers found these interactions may play a role in inflammatory diseases like Crohn’s. It’s a major shift in how scientists understand the microbiome’s power over human health.
Glyphosate: A story of science, risk, and nuance
In the summer of 2014, a California groundskeeper named Dewayne Johnson started noticing patches of raw, weeping skin spreading across his body. He had spent years applying Roundup, Monsanto’s glyphosate-based herbicide, for a school district, sometimes drenched in it when equipment malfunctioned. By 2014, he had a diagnosis: non-Hodgkin’s lymphoma. In 2018, a jury awarded him $289 million in damages, later reduced on appeal. Tens of thousands of lawsuits followed. The story hasn’t quieted down. It’s all over the internet, swinging between “this will kill you, buy organic” and “relax, you’re fear-mongering.” Some of that recent chatter stems from an Executive Order protecting glyphosate and its production, which set off intense infighting within the MAHA movement. Some of it reflects a deeper truth: Americans genuinely care about harmful chemicals in their environment (see poll below). And the conversation isn’t going anywhere, with a Supreme Court case involving Monsanto set for this April. Glyphosate (the active ingredient in Roundup) is one of the most widely used herbicides in the world. But does glyphosate cause cancer? And how much exposure is actually risky? With so much mistrust in institutions and corporations (and some genuine conflicts of interest), making sense of the actual scientific evidence is genuinely hard. Here is a translation of what the scientific evidence actually says. Does glyphosate cause harm? Glyphosate is an herbicide that kills most plants it contacts rather than targeting specific species. It works by blocking an enzyme pathway (EPSPS) that plants and many microorganisms need to produce essential amino acids. Without those amino acids, the plant can’t grow and dies. Glyphosate was first developed by Monsanto in the 1970s and became ubiquitous after the company introduced “Roundup Ready” crops in the 1990s. In 2024, Bayer removed glyphosate from residential Roundup-branded products due to litigation pressure. But today it is still the most widely used herbicide in the world. Farmers also discovered they could spray it directly on crops like oats, lentils, beans, and peas just before harvest to dry them out faster and make harvesting easier. Because of its widespread use, it’s obviously really important to understand if it’s harmful to humans. The key principle: The dose makes the poison The most important concept in toxicology is that “the dose makes the poison.” Sixteenth-century physician Paracelsus articulated what remains the foundational principle of toxicology: sola dosis facit venenum. Water will kill you if you drink enough of it. Aspirin saves lives at 81 milligrams and causes internal bleeding at higher chronic doses. So, at what dose is glyphosate poisonous? The LD50 in rats (the dose that kills half the test animals) is around 5,600 mg/kg body weight. Table salt is roughly 3,000 mg/kg. By that classic measure, glyphosate is less acutely toxic than salt. But some people are exposed to a lot of glyphosate through their work. And among the general public, there are many questions about low-dose, cumulative exposure from multiple sources over long periods. Does glyphosate cause health problems? Cancer Correlation maps are striking, with one analysis finding that 60% of counties that spray the most glyphosate have non-Hodgkin’s lymphoma rates above the national average. But correlation alone doesn’t establish cause, which is why animal and human studies matter. In animals: Rat studies are typically what most fear is rooted in, but most people don’t know the study details on the dosage given to rats. A pooled analysis of the 13 most rigorous rat studies found evidence that very high doses, around 55,000 times greater than typical food residue exposure, can cause certain cancers. In humans: One of the strongest studies followed 55,000 herbicide users over 20 years and found no overall increased cancer risk. There was one signal: among those with the highest use, rates of acute myeloid leukemia (AML) appeared elevated. A broader meta-analysis of 18 human studies also found no overall cancer risk, though a separate meta-analysis focused specifically on non-Hodgkin lymphoma found that people with high cumulative glyphosate exposure faced a 41% higher relative risk compared to those with low or no exposure. These human studies are observational studies (randomized controlled trials would be unethical), and meta-analyses are only as reliable as the studies they pool. But the story seems consistent: at very high exposure levels, there may be some cancer risk. But that’s about as far as the science currently takes us. Emerging research: gut and reproductive health Gut: Because glyphosate targets a pathway that exists in some gut bacteria, scientists have questioned whether it could affect the microbiome. In mice, a 2023 University of Iowa study found that glyphosate altered gut bacterial composition and raised markers of intestinal inflammation. A 2024 systematic review found similar patterns: disrupted gut bacteria and problems with the mucus layer that protects the intestinal wall in mice. Whether this translates to humans is an open question. The human gut is highly variable and resistant, and we don't yet have strong studies confirming the same effects in people. Reproductive health: Animal studies have found that glyphosate-based herbicides can interfere with reproductive hormones, including disrupting egg cell development in mice and reducing the number of eggs available in sheep’s ovaries. However, the doses used in these experiments were high, so it’s not yet clear whether the same effects would occur in humans. On the human side, a 2021 pilot study led by Mount Sinai researchers tested urine samples from pregnant women across the U.S. and found glyphosate in 95% of them. The study also found a possible connection between higher glyphosate exposure during pregnancy and a subtle physical difference measured in female newborns. That said, some connections weren’t statistically reliable and this was a small study. The researchers themselves said more and larger studies are needed before drawing firm conclusions. What do regulators say about glyphosate safety? In 2015, the International Agency for Research on Cancer (IARC), part of the World Health Organization, classified glyphosate as "probably carcinogenic to humans" (Group 2A). The classification is worth taking seriously. But, there’s an important distinction: IARC classifies hazard, meaning the potential to cause harm under some conditions. It does not assess risk, which accounts for actual exposure levels and the real-world probability of harm. The U.S. EPA, the European Food Safety Authority, Health Canada, and regulatory agencies in Australia and Japan have all concluded that glyphosate is “unlikely to be carcinogenic to humans” at realistic exposure levels. They’re asking a different question: given how much of this people actually encounter, what is the probability of harm? Your actual exposure is what determines your actual risk. What does glyphosate mean for your daily life? At the grocery store: Food residues are small. The EPA’s acceptable daily intake is 1.75 mg/kg of body weight per day. To hit that threshold from oatmeal alone, a 150-pound adult would need to eat roughly 50 pounds of oats every day. But this calculation addresses only one pathway (food), and we don’t yet have robust tools to measure people’s actual total exposure. If reducing exposure matters to you, organic certification prohibits synthetic herbicides, and organic oat products generally test at lower or undetectable levels. Either way, a diet rich in whole grains, conventional or organic, is far better for your health than one that omits them out of fear of residues. On the farm: Occupational exposure is orders of magnitude higher than consumer exposure. Farmers and farm workers who mix, load, and apply glyphosate-based herbicides, especially without protective equipment, face meaningfully different risk profiles. Proper PPE isn’t optional. Integrated weed management strategies that rotate chemical modes of action are also worth taking seriously, both for health and for long-term effectiveness. If you live near a farm: Spray drift is real. Concentrations near field edges can spike during and after application, particularly on windy days. This is an area where I think public health could really step up and empower rural communities with buffer zones, rather than placing the onus on individuals. But for now, knowing your local agricultural calendar and keeping windows closed during application are the first steps. Bottom line Dewayne Johnson was exposed to glyphosate at levels most people will never encounter, and a jury decided he deserved compensation. That outcome is not evidence that the oatmeal in your pantry is dangerous. But it is a reminder that the dose, the context, and the person doing the exposing all matter enormously. Glyphosate is a chemical tool with benefits, trade-offs, and genuine open scientific questions. Learning to hold that complexity without collapsing into panic or dismissal is, honestly, one of the most useful and hardest things to do in navigating modern health science. Love, YLE Your Local Epidemiologist (YLE) is founded and operated by Dr. Katelyn Jetelina, MPH PhD—an epidemiologist, wife, and mom of two little girls. Hannah Totte, MPH, is an epidemiologist and YLE Community Manager. YLE reaches more than 425,000 people in over 132 countries with one goal: “Translate” the ever-evolving public health science so that people will be well-equipped to make evidence-based decisions. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe
Scientists Call for a Complete Rethink of Alzheimer’s Treatment
New insights suggest that Alzheimer’s cannot be tackled through a single pathway, as its roots extend across molecular, genetic, and systemic processes.
How can you explore careers worldwide? Binghamton student founds club to find out
Binghamton University School of Management student Liam Foley discovers how connecting with diverse cultures creates new pathways for success after founding an international business club.
A surprising foam discovery could change everyday products
Foams have long baffled scientists because liquid drains from them far sooner than theory predicts. New research shows the reason: the bubbles don’t stay put—they rearrange, opening pathways for liquid to escape. The key factor is the pressure needed to shift bubbles, not just push liquid through them. This insight reshapes how we understand foams and could improve everyday products.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Forum on harnessing Artificial Intelligence for health equity
Register to this forumOver the past decade, artificial intelligence (AI) has significantly evolved in complexity, performance, and utility. Its integration across a wide range of industrial sectors has accelerated, with healthcare emerging as one of the most transformative sectors. In this sector, AI has enabled high-impact applications – from enhancing the speed and accuracy of disease diagnosis and supporting clinical decision-making, to strengthening public health initiatives such as disease surveillance and workforce optimization. Moreover, AI holds immense potential to empower individuals, enabling them to take greater control of their personal health and well-being. Yet the central question remains: Who benefits, who is at risk, and do these innovations close or widen health inequities? While the potential of AI-enabled applications is substantial, many countries have approached their adoption with caution. This hesitancy stems from concerns about risks and benefits, including model bias, data breaches, privacy violations, and the erosion of professional skills due to over-reliance on AI. Additional barriers include inadequate data infrastructure and a lack of robust evidence on the most effective forms and interfaces of AI to enhance service delivery and system performance. Moreover, the rapid rise of Generative AI has introduced a heightened urgency for the development of comprehensive governance and ethical frameworks. The Asian Development Bank (ADB) Health Practice Team and Digital Sector, in collaboration with the World Health Organization (WHO) Regional Office for the Western Pacific, are convening the Forum on Harnessing AI for Health Equity on 25–26 March at ADB Headquarters. Senior health officials from 16 developing member countries (DMCs), alongside leading researchers, innovators, and policymakers from across Asia and the Pacific, will engage in discussions on how AI can be governed, financed, and scaled to deliver healthier lives for all. The forum is funded through the High-Level Technology Fund with support from the Government of Japan. Objectives The two-day forum aims to:Identify high-impact, evidence-based health AI use cases suitable for resource-constrained settings and map out a pipeline for potential supportIntroduce and validate the WHO's policy guidance on minimum necessary ecosystem for countries and institutions to self-assess readiness for AI adoptionObtain initial commitment from participating stakeholders to join a pilot regional initiative focused on data/model sharing for a priority health challengeEndorse a prioritized set of actionable policy recommendations focusing on governance, regulation, and sustainable financing necessary to scale high-impact health AI use cases in resource-constrained settings Target participants The forum will convene participants from 16 ADB DMCs including Bangladesh, Bhutan, Cambodia, Cook Islands, Fiji, Indonesia, Lao People's Democratic Republic, Mongolia, Nepal, Palau, Papua New Guinea, Philippines, Sri Lanka, Thailand, Uzbekistan, and Viet Nam. In addition, health system leaders and practitioners, private sector technologists, academic experts, representatives from civil society organizations, development partners, and philanthropic institutions engaged in AI for Health from Australia, the People’s Republic of China, Japan, Malaysia, New Zealand, Singapore, and the Republic of Korea will also be invited. SessionsDay 1 (25 March)Session 1: AI Use Cases for the Care Continuum: Improving Access and QualitySession 2: Adopting a risk-based approach for AI use case prioritizationSession 3: Establishing the Minimum Ecosystem for Implementation Risk ManagementSession 4: Future-Ready Health Workforce: Building Competency for Human-AI CollaborationDay 2 (26 March)Session 5: The Political Economy of AI in Health: Understanding Stakeholder Interests and their Impact on EquitySession 6: AI and Health Financing: Supporting Fair Coverage and ProtectionSession 7: AI Regulation and Oversight: Pathways for Different RealitiesSession 8: The Way Forward – Building Alliances and Regional Partnership How to registerThe forum will be held in a hybrid format. In-person attendance is by invitation only, while livestreaming of the forum will be available to the public. To register, please complete this form on or before 24 March 2026.Event organizers / partnersAsian Development Bank (ADB)WHO Regional Office for the Western Pacific High-Level Technology Fund (HLTF)ContactAkihito WatabeHealth Specialist, SD3-HSDawatabe@adb.org Jae Kyoun KimHealth Specialist, SD3-HSDjkkim@adb.org
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Mental health solutions for the digital age
Ask the digital natives of Gen Z about the source of their biggest mental health challenges, and most will say social media and AI.Several of the nearly 400 guests at the third annual Gen Z Wellness Summit, presented by the Friends of Semel Teen Advisory Council at UCLA on March 8, explicitly named the endless stream of content on their phones as serious stressors. “Everybody is addicted to (Tik Tok) as if they were addicted to substances,” said Jantin Asmar, 17, a senior at Virtual Academy in Antelope Valley. “We’re always chasing that dopamine. We’re expecting that dopamine rush and it’s really decaying our interactions with others.” High school student Jantin Asmar was among nearly 400 people who attended the third annual Gen Z Wellness Summit. (Photo by Sandy Cohen) Even young teens feel pressure to be on social media constantly, both to consume content and collect “likes,” said 13-year-olds Chloe and Sophia, both students at Brentwood School. “Everyone’s always on, and you miss stuff if you’re not on it,” Chloe said, adding that social media’s emphasis on appearances is leading to eating disorders: “That’s a big thing for our generation.”The incessant influx of images and updates creates expectations that “weigh teenagers down,” said Linda Kou, 16, a junior at San Gabriel High School.Even though digital spaces allow people to connect with others beyond their immediate surroundings, it doesn’t always translate to real-life community, said Kelah Morgan, 17, a senior at Animo South Los Angeles Charter High School. High school students Kelah Morgan, left, and Linda Kou, shared about the challenges presented by social media. (Photo by Sandy Cohen) “Even if you see people saying that they relate to you online, it might be hard to find people in your personal life who you see every day who you feel comfortable enough to say, ‘You see me online, but this is me in real life and what I’m actually going through,’” she said.Solutions for our digital timesThe Gen Z Wellness Summit was intentionally designed as a free, in-person gathering where young people interested in mental health from across the southland could meet in person. “Peer support is the most important element of maintaining our mental health in community,” said Helena Hansen, MD, PhD, director of UCLA’s Semel Institute for Neuroscience and Human Behavior.Keynote speakers at the summit addressed AI, social connection and self-empowerment, while breakout sessions included discussions about eating disorders, dating, substance use, phone detox and breathwork. Here are some of the day’s top takeaways:Beware of FOPO: Scott Barry Kaufman, PhD, a psychology professor at Columbia University, said that rather than FOMO, or fear of missing out, we ought to be more aware of FOPO: fear of people’s opinions. “Just think about how much your FOPO might be holding you back in your life,” Dr. Kaufman said. “And just that inner contemplation should be enough for you to change your life, because there’s so many things we don’t go after because we have debilitating FOPO.”We don’t need to feel like we’re the best – or what he called “narcissistic self-esteem” – but it’s helpful to acknowledge our own worth, recognize our good qualities and develop self-belief in the skills and talents we’ve cultivated. When we have that – dignity and self-respect, without needing everyone to like us – FOPO is less of a concern.Self-reflection is most effective in community: “When we try to self-reflect alone, we sometimes ruminate,” said Ira Bedzow, PhD, executive director of the Emory University Purpose Project. “But when we self-reflect with people that we trust … (it) allows us to hold ourselves accountable to different ways of seeing and different ways of hearing and different ways of being.”Opening up about our experiences and listening to others are skills we can develop, Dr. Bedzow said.He invited students to participate in what he called a “fishbowl exercise,” where four students sat in a small circle, surrounded by a dozen or so students forming a larger circle. Those in the inner circle answered such questions as: “What stops you from being you today?” and “What helps you feel most like you?”Within minutes, the group in the small circle (the fishbowl), were sharing intimately about their life challenges as those in the outer circle nodded in understanding.After the exercise, one participant said, “I felt like I wasn’t alone, that it wasn’t just me who feels that way.”Another remarked on how “personal” it felt to share face-to-face with others, even strangers.Don’t let AI crush your creativity: Theoretical neuroscientist Vivienne Ming, PhD, has been studying artificial intelligence for more than 20 years. And while she said “it’s reasonable to be concerned” about the fast-growing technology, it can also help humans become better problem-solvers when used strategically.“The smartest thing on the planet today are humans and machines working together creatively,” Dr. Ming said. “What gets more valuable in humans as machines get smarter? Our ability to explore the unknown.“Your unique voice is literally your value to the world … but most of us for most of our lives have been taught to not be unique,” she continued. “Be your own person. Celebrate being different. It is genuinely, measurably, truly valuable.”In a breakout session called “Phone Detox? IYKYK: Living Your Story IRL” led by Don Grant, PhD, students shared their frustrations with AI compromising academic work, art and creativity.“Art is a translation of human experience,” one participant said. “When people use AI, they diminish their own human experience.”Dr. Grant urged them, as “the last generation to remember a world before AI,” to remember the power of imagination and creativity – and to act on it.Remember that social media distorts perceptions: Stuart B. Murray, PhD, PsyD, who directs the Eating Disorders Program and Translational Research in Eating Disorders Program at UCLA, asked the students in his breakout session to take a spontaneous selfie and edit it to conform with society’s beauty standards. All 20 girls in the room immediately got to work, thickening their hair, slimming their faces, plumping their lips.“The pressure to look like what we present on social media can be crippling,” Dr. Murray said. “We now know that social media use is part of a causal pathway into an eating disorder.”Adolescents and young adults are most at risk of developing an eating disorder, he said, with one in three students on college campuses exhibiting clinically meaningful eating-disorder symptoms. More than 4 million people in California will have an eating disorder in their lifetime.Even for those who don’t develop anorexia or bulimia, the ubiquity of modified images online distorts what we consider normal, making us feel worse about ourselves. Remembering that, he and other speakers said, might inspire us to log off occasionally and spend time in the real world with people who love us as we are.
Health Equity in Action: Building Pathways to Care and Community Well-Being
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Scientists discover a brain signal that may trigger autism’s domino effect
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Scientists find the genetic switch that makes pancreatic cancer resist chemotherapy
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Drexel and Cooper University Health Care Announce Partnership to Advance Nursing Careers Through Experiential Learning
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Global webinar on core public health capacities to conduct ship inspections and issue ship sanitation certificates
Ships cross borders every day, connecting countries and serving as a backbone of the global economy. However, outbreaks onboard can disrupt maritime traffic, leading to significant economic and operational negative consequences. Without strong public health capacities to detect, prevent, and respond to public health risks on board ships, maritime travel can also become a pathway for the spread of infectious diseases. To support countries in strengthening these capacities, the World Health Organization (WHO) convened a two-day webinar on 11–12 February, bringing together more than 700 ship inspectors, port health officers, and public health authorities, primarily from the African, Eastern Mediterranean, and European Regions. The webinar came at a pivotal time. With the amended International Health Regulations entering into force on 19 September 2025, the need to focus on public health preparedness has never been greater. Strengthening public health capacities at borders, including onboard conveyances, is a cornerstone of global health security and central to the amended IHR.“The high level of attendance and active participation throughout the two days of the webinar highlighted the growing demand for technical guidance and capacity-building support in ship inspection and issuance of ship sanitation certificates”, said Dr Ninglan Wang, Head of the Borders, Mass Gatherings and Health Protection Measures (BMM) Unit at the Health Emergency Preparedness Department at WHO headquarters. “The dynamic interactions among experts and countries underscored the value of continued cross-border collaboration in the maritime sector and knowledge exchange in this area”. Conducting regular public health inspections on board ships for the issuance of ship sanitation certificates (SSCs) in accordance with the IHR requirements is crucial for ensuring that ships meet specific health standards, thereby minimizing the risk of the international spread of diseases via maritime traffic. These certificates, mandated by the IHR, require ports to have trained personnel who can identify and control public health risks on board vessels and apply recommended control measures. This standardized global procedure not only ensures compliance with the IHR but also promotes consistency in health practices across ports worldwide. SSCs are the globally-recognized tool used to prevent and control known public health risks on ships, providing a common way to register and communicate public health events and measures taken on board between all stakeholders involved in this process, including public health authorities in ports and ship operators. Only SSCs issued by ports authorized by national authorities to issue such certificates are considered valid. As per the IHR, all States Parties are required to send to WHO their list of authorized ports (available here) and to keep it updated. However, many Member States continue to face practical challenges, such as limited resources, high staff turnover, and competing priorities. These realities underscore the value of platforms such as this webinar, which foster collective learning, peer-to-peer exchange, and practical solutions to help countries build and sustain the capacities required under the IHR.Over the two days, participants engaged in presentations and discussions covering a wide range of technical and operational topics, such as the overarching international legal framework governing ship sanitation; considerations for pre-inspection planning; risk assessment factors by type of vessel; the completion and issuance of SSCs and evidence report forms; or practical insights on the inspection of various technical areas, such as food safety, medical facilities, water systems, or vector control, among others. In addition, public health authorities from the Netherlands, Morocco, and Tanzania shared case studies to showcase their practical application of these IHR requirements in their respective countries. Given its success, WHO plans to replicate similar sessions in the future to reach additional time zones and regions and cover other pressing border health-related topics, ensuring that Member States can continue benefiting from these opportunities to share knowledge and expertise.
PRET for impact: Advancing pandemic preparedness in the Democratic People’s Republic of Korea
IN THE SPOTLIGHT PRET for impact: Advancing pandemic preparedness in the Democratic People’s Republic of KoreaThe Democratic People’s Republic of Korea (DPR Korea) is making significant progress in strengthening pandemic preparedness, with dedicated support from the WHO South‑East Asia Regional Office (SEARO) and the Pandemic Influenza Preparedness (PIP) Partnership Contribution (PC).Aligned with the WHO Global Influenza Strategy and the Pandemic Influenza Preparedness (PIP) Framework Partnership Contribution High‑Level Implementation Plan III (2024–2030), the country is strengthening its capacity to prepare for and respond to influenza and other respiratory threats. In early 2025, a core team from the Ministry of Public Health of the Democratic People’s Republic of Korea (DPRK) participated in a two‑day virtual workshop, which included a mini‑simulation exercise. The workshop was organized by WHO SEARO in collaboration with the Preparedness and Resilience for Emerging Threats (PRET) Secretariat at WHO headquarters and the WHO Country Office for the DPRK. Read more A REGIONAL CONSULTATION GUIDES WHO SEARO IN DEVELOPING A ROADMAP FOR IMPLEMENTING THE PREPPAREDNESS AND RESILIENCE FOR EMERGING THREATS (PRET) INITIATIVE BASED RESPIRATORY PATHOGEN PANDEMIC PREPAREDNESSInfluenza and other respiratory pathogens with pandemic potential continue to pose major public health risks globally. To strengthen regional preparedness and response, Member States of the WHO South‑East Asia Region (SEAR) convened in Colombo, Sri Lanka, to review and provide input on the draft Roadmap and Action Framework for Broad Respiratory Pathogen Pandemic Planning (2026–2031). Supported through the Pandemic Influenza Preparedness (PIP) Partnership Contribution (PC) funds, the proposed roadmap aims to advance robust, integrated preparedness and response capacities for influenza and other respiratory threats across SEAR. This work is aligned with the Preparedness and Resilience for Emerging Threats (PRET) initiative and the SEAR Strategic Roadmap on Health Security and Health System Resilience for Emergencies Read moreSRI LANKA’S USE OF ANTIVIRALS TO REDUCE THE SEASONAL INFLUENZA BURDEN Sri Lanka is strengthening its influenza response by placing greater emphasis on rapid testing, timely treatment, and integration with maternal health services. With support from WHO, the country is building a stronger evidence base on the burden of influenza and the value of vaccination, advancing a holistic approach to protect vulnerable populations and enhance pandemic preparedness. To reduce hospitalizations and deaths from seasonal influenza, Sri Lanka is taking proactive steps to expand access to rapid diagnostic testing and ensure prompt initiation of treatment. National clinical guidelines recommend the use of oseltamivir for individuals at high risk of complications, helping prevent severe illness and shorten the duration of infection. This strategy not only saves lives but also supports local pharmaceutical production, contributing to a reliable supply of antivirals for both seasonal outbreaks and future pandemics.Read moreBHUTAN BOOSTS PANDEMIC INFLUENZA READINESS WITH PANDEMIC INFLUENZA PREPAREDNESS FRAMEWORK PARTNERSHIP CONTRIBUTION SUPPORTED TRAINING AND SIMULATIONSOriginally developed in 2012, the National Influenza Pandemic Preparedness and Response Plan (NIPPRP) has long served as Bhutan’s central framework for managing influenza threats. In 2024, the plan underwent a comprehensive update to reflect evolving global and regional guidance, lessons learned from the COVID‑19 pandemic, and new capacities developed under the PIP Framework. The revised NIPPRP is now more clearly aligned with Bhutan’s broader emergency and disaster risk management structures, ensuring a coordinated, whole‑of‑government approach to pandemic response. As part of efforts to strengthen national pandemic preparedness, Bhutan conducted three national‑level training sessions followed by simulation exercises on influenza pandemic preparedness and response at five sentinel hospitals between April and May 2025, with support from the PIP Partnership Contribution (PC). These activities brought together more than 140 health professionals and key partners from across the country, with a focus on operationalizing the updated NIPPRP and enhancing readiness at key frontline facilities. Read moreSTRENGTHENING INFLUENZA SURVEILLANCE: WHO BRINGS TOGETHER INFLUENZA EXPERTS FROM SOUTH-EAST ASIA AND WESTERN PACIFIC REGIONSThe World Health Organization (WHO) convened the 18th Bi‑regional Meeting of National Influenza Centres (NICs) and Influenza Surveillance for the WHO South‑East Asia and Western Pacific Regions from 9–11 September 2025. Hosted by the WHO South‑East Asia Regional Office (SEARO), the meeting brought together representatives from Member States, Territories, and Areas across both regions, alongside experts from the WHO Collaborating Centres for Reference and Research on Influenza in Australia and Japan, the WHO Collaborating Centre for Studies on the Ecology of Influenza in Animals in the United States, quadripartite partners (WOAH and FAO), and other technical counterparts. The consultation provided a platform to review progress, share experiences, and outline priorities for strengthening influenza and respiratory pathogen surveillance across the two WHO regions.Read moreNETWORKS AND TECHNICAL PARTNERSHIPSSTRENGTHENING PANDEMIC READINES: SOUTH-EAST ASIA ADVANCES UNITY STUDIES UNDER THE PANDEMIC INFLUENZA PREPAREDNESS INITIATIVEThe WHO Global Influenza Surveillance and Response System (GISRS) Investigations & Studies initiative, also known as Unity Studies, provides a standardized, globally coordinated framework to support these efforts. Originally developed for influenza and adapted during COVID-19, Unity Studies enable countries to conduct rapid, nationally led investigations and studies to assess transmissibility, severity, susceptibility, and intervention effectiveness. To better prepare for future influenza pandemics, WHO has recently launched a network of sites which will be ready to conduct these investigations and studies rapidly in the event of a pandemic, or epidemic of an emerging or re-emerging respiratory pathogen. The WHO South-East Asia Region now hosts six sites of WHO GISRS Unity Studies across the five countries including Sri Lanka, strengthening regional capacity for early pandemic investigations. From 13–16 July 2025 in Colombo, the Global Public Health Summit offered an opportunity to advance this agenda. Read moreSTRENGTHENING PANDEMIC PREPAREDNESS THROUGH UNITY STUDIES: REAL-WORLD APPLICATIONS FROM INDIA IN WHO’S SOUTH-EAST ASIA REGION As countries continue to strengthen their pandemic preparedness through investments in resilient health systems during the interpandemic period, the World Health Organization’s (WHO) Global Influenza Surveillance and Response System (GISRS) Investigations & Studies Global Initiative, Global Initiative, commonly known as Unity Studies, remains a vital framework for respiratory pathogen pandemic preparedness. These standardized epidemiological protocols enable countries to rapidly generate high‑quality data on transmissibility, infection severity, population immunity, and the effectiveness of public health interventions. To highlight how Unity Studies protocols are being adapted and applied in national settings, WHO Headquarters, together with WHO Regional Offices, including the WHO South‑East Asia Regional Office (SEARO), hosted a global webinar. The session showcased case studies from India and the United Kingdom (UK), demonstrating innovative approaches to respiratory virus surveillance and pandemic readiness. Read moreSTRENGTHENING REGIONAL INFLUENZA SURVEILLANCE AND PREPAREDNESS: WHO SEARO HOSTS HIGH-LEVEL WEBINAR AMID RISING H5 THREATS In response to the increasing detection of avian influenza A(H5) cases in humans globally and within the WHO South‑East Asia Region, the WHO Regional Office for South‑East Asia (SEARO) convened a regional webinar on 25 July 2025 to review preparedness mechanisms, strengthen surveillance pathways, and promote timely reporting of unusual respiratory events. The virtual session brought together more than 50 participants from Ministries of Health, National Influenza Centres (NICs), National IHR Focal Points (NFPs), WHO Headquarters, WHO Country Offices across the Region, and WHO Collaborating Centres (CCs) for influenza. The webinar provided an opportunity to share situational updates, discuss surveillance gaps, and reinforce coordination mechanisms critical for early detection and rapid response to avian influenza threats. Read moreOther Key PIP Updates (July-December 2025)MEMBER STATES:Bangladesh drafted and conducted a series of Core Group Meetings in 2025 to review and update the National Pandemic Preparedness and Response Plan for Respiratory Pathogens. In addition, the country carried out Rapid Response Team (RRT) trainings on seasonal and avian influenza and other re‑emerging infectious diseases. Bangladesh also updated its epidemiological data‑training programme for physicians at sentinel surveillance sites, using a revised epidemiological data‑collection tool.Bhutan revised and updated its National Influenza Pandemic Preparedness and Response Plan (NIPPRP) in 2025 and developed a national Standard Operating Procedure (SOP) for influenza outbreak management. DPR Korea conducted a nationwide simulation exercise in July 2025 to support the update of its National Influenza Pandemic Preparedness Plan (2019). This followed a PRET‑based virtual orientation and mini‑simulation exercise held in May 2025 by SEARO and the WHO PRET Secretariat. The comprehensive exercise, conducted across central and provincial levels, assessed strengths and gaps in pandemic influenza preparedness and response. The feedback gathered has been incorporated into the revised draft plan to address identified weaknesses and strengthen overall readiness.India conducted a targeted nationwide online re‑orientation training on review and updates to the influenza portal for all State Surveillance Officers (SSOs) and relevant officials using the Integrated Health Information Platform (IHIP). The training emphasized correct marking and reporting of influenza samples as “unsubtypable” or “not subtyped” where applicable, to ensure accurate national surveillance.Maldives conducted simulation exercises in three atolls based on its existing National Pandemic Preparedness and Response Plan (NPPRP). The country plans to conduct similar exercises in three additional atolls after updating the NPPRP in 2026. In addition, Maldives conducted training on FluID and FluMart as part of a broader data‑management training package for Ministry of Health and Health Protection Agency officials, aimed at improving routine reporting to WHO platforms and the DHIS2 system.In Myanmar, technical support was provided to the National Influenza Centre (NIC) through dedicated human‑resource support (January–December 2025) to sustain data management and laboratory detection capacity for influenza and other emerging and re‑emerging respiratory viruses. This support also included strengthening genomic sequencing capacity.Nepal conducted a consultative workshop on the National Pandemic Preparedness and Response Plan (NPPRP) in July 2025. The workshop engaged key stakeholders from multiple sectors to review lessons from past pandemic responses, assess current mechanisms, and gather critical inputs for strengthening national preparedness. Key recommendations included revising the 2019 NPPRP and developing an updated Influenza Pandemic Preparedness Plan aligned with emerging risks, national priorities, and relevant international frameworks. Nepal also held a two day workshop dedicated to advancing the National Action Plan for Genomic Surveillance, aimed at reinforcing the country’s capacities for early detection and monitoring of emerging respiratory pathogens.Sri Lanka received the final report from WHO on the feasibility assessment for conducting an Influenza Burden of Disease (BoD) study in the country. The assessment, conducted from 28 April to 9 May 2025, included a desk review of existing data sources, document review, visits to sentinel surveillance sites, and key informant interviews. The study identified critical data sources required for a future BoD assessment, as well as their availability and quality. Officials from the Epidemiology Unit, the National Influenza Centre (NIC), and SARI/ILI sentinel hospitals across the country participated in the assessment.Timor Leste conducted on‑the‑job training and monitoring activities at two sentinel surveillance sites to strengthen surveillance and laboratory capacity for the detection of SARI, ILI, ARI, and other respiratory infections. REGIONAL OFFICE:SEARO conducted a Member States Consultation on the first draft of the Regional Roadmap and Strategic Action Framework for implementing WHO’s PRET‑based broad respiratory pathogen pandemic planning for 2026–2031. The consultation took place on 29–30 October 2025 during the final two days of the Regional PIP PC Annual Review and PRET Meeting in Colombo, Sri Lanka. Participants included representatives from Member States, WHO Country Offices, WHO SEARO, WHO Headquarters, partner agencies, and invited multidisciplinary technical experts. They reviewed the draft and provided detailed feedback, which has since been incorporated into a revised version. The consultation helped shape a shared regional vision for robust, PRET‑aligned pandemic preparedness, building on country‑level progress, addressing existing gaps and challenges, and aligning with global and regional health security frameworks. The publication is planned for release during the SEAR regional committee in 2026.SEARO documented the evolution of the National Influenza Pandemic Preparedness Planning process in the Region, tracing its development from its origins as a planning tool for responding to avian influenza outbreaks in 2006, through the experiences of the 2009 and 2019 pandemics, to the current status. The document outlines the way forward for respiratory pathogen pandemic planning across all 10 SEAR countries, aligning future national plans with WHO’s PRET Framework for broad respiratory pathogen pandemic preparedness.The Infectious Hazard Management (IHM) Unit has drafted the WHO South‑East Asia Regional Guidance on Influenza Prevention and Control, aligned with the Global Influenza Strategy and other regional initiatives. The draft is currently under review. Although this technical product was developed in response to a request from the Ministry of Public Health of the Democratic People’s Republic of Korea (MoPH‑DPRK), SEARO is finalizing it for use not only in DPRK but also across all Member States in the Region.The Immunization and Vaccine Development (IVD) Unit, in collaboration with WHE/SEARO, completed a regional landscape analysis on key barriers, challenges, and opportunities for the introduction of seasonal influenza vaccination in WHO South‑East Asia Regional (SEAR) countries.Additionally, the Immunization and Vaccine Development (IVD) Unit has completed a regional landscape analysis of influenza vaccine procurement systems across the WHO South‑East Asia Region (SEAR).KEY MEETINGS AND PUBLICATIONSMEETINGS:Six-month progress review of the implementation of the PIP-PC workplans in SEAR, focusing on Outputs 1 and 2 for the period January to June 2025, and held virtually across three sessions on 4, 8, and 10 July 2025. Read moreAnnual Regional Meeting (Hybrid) on Pandemic Influenza Preparedness (PIP) Partnership Contribution (PC) and WHO’s Preparedness and Resilience for Emerging Threats (PRET) Implementation in SEAR in Colombo, Sri Lanka, 27 to 30 October 2025. Read more18th Bi-regional Meeting (Virtual) of National Influenza Centres (NICs) and influenza surveillance in WHO South-East Asia and Western Pacific Regions from 9 to 11 September 2025. Read morePUBLICATIONSImplications of influenza A virus surveillance in Southeast Asian Region countries: a scoping review of approaches for the surveillance of swine influenza viruses at human-swine interfaces. Read moreAnnual South-East Asia regional meeting on operational planning for implementation of global influenza strategy and preparedness for respiratory viruses in 2025 Report on annual review meeting of implementation of pandemic influenza preparedness (PIP) partnership Contribution (PC) Fund in South-East Asia Region and the simulation exercise on PRET Status of influenza in who south-East Asia Region
Plasma proteomic profiles linked to suicidal behaviors
Nature Mental Health - Using plasma proteome profiles from over 53,000 UK Biobank participants, Zhang et al. examined proteins associated with suicidal behavior and investigated pathways that could...
Governor Gianforte Mentors Great Falls Students on Careers in Technology and Business
GREAT FALLS, Mont. – Governor Greg Gianforte recently visited Great Falls High School to address students and discuss the pathways to careers in technology, business, and entrepreneurship. The Career Exploration class at Great Falls High School is being offered this semester to give students the opportunity to hear directly from Montanans in different career fields.
Scientists reveal how exercise protects the brain from Alzheimer’s
Exercise may sharpen the mind by repairing the brain’s protective shield. Researchers found that physical activity prompts the liver to release an enzyme that removes a harmful protein causing the blood-brain barrier to become leaky with age. In older mice, dialing down this protein reduced inflammation and improved memory. The discovery points to a surprising body-to-brain pathway that could inspire new Alzheimer’s therapies.
Singapore Alternative Lending Business Market Report 2026-2029: BNPL and Embedded Finance Market Intensifies as Atome, Grab PayLater and Shopee SPayLater Compete with Bank-Led Instalment Expansion
Key market opportunities in Singapore's alternative lending include BNPL standardization favoring accredited providers, embedding SME credit within digital ecosystems, tightening digital acquisition standards, and expanding private credit funding pathways. These shifts could enhance regulatory compliance, market reach, and investment potential. Singaporean Alternative Lending Market Singaporean Alternative Lending Market Dublin, Feb. 19, 2026 (GLOBE NEWSWIRE) -- The "Singapore Alternative Lendin
Olympics Provide a Pathway for New Sports Fans
Share of Ear from Edison Research has chronicled Spotify's rise in popularity, now reaching 25% of Americans 13+ daily.
Main Street begins legal process toward winddown
Main Street Sports Group has initiated its legal pathway to a winddown on Tuesday by issuing WARN notices to all employees, alerting them that, as of now their jobs will end in approximately 60 days when the NBA and NHL regular seasons conclude in mid-April.
OPINION: Pathways for future scientists are becoming scarce, threatening a strong and innovative workforce
If we want a scientific workforce capable of addressing the challenges we face, we must invest in scientists long before they become scientists. That means expanding research opportunities, supporting students early and building trust with communities.
Asteroid Bennu reveals a new pathway to life’s chemistry
Dust from asteroid Bennu is revealing a surprising origin story for life’s building blocks. New research suggests some amino acids formed in frozen ice exposed to radiation, not warm liquid water as scientists long believed. Isotopic clues show Bennu’s chemistry differs sharply from well-studied meteorites, pointing to multiple pathways for creating life’s ingredients.
2025 US ACT on Health Equity Community Investments Recipients
Author: Kennesha VanBurch, Director, Health Equity and Community Investment Partnerships 2025 marks the fifth year of the US Accelerate Change Together (ACT) on Health Equity: Community Solutions Challenge (CSC) and National Strategic Collaborations (NSC). This year, we received more than 250 applications from organizations across the country dedicated to prioritizing the social, cultural and linguistic needs of communities that have experienced barriers to care and opportunity. The overwhelming response underscores the vital role these organizations play in advancing health equity at the local level and across the nation. Since the launch of ACT on Health Equity in 2021, the initiative has invested more than $18 million in nonprofit organizations and their health equity programming through CSC and NSC. This year, $3.4 million in funding has been provided to 47 nonprofit organizations that focus on healthcare access, nutrition and lung health. Together, we are making meaningful progress toward health equity across the US. Supporting Organizations Advancing Community Well-being and Health Equity The awarded organizations address critical needs across health, education, and social support through initiatives aligned with AstraZeneca’s areas of expertise, including lung disease, lung and breast cancer, and cardiology. Their work spans across culturally competent senior care, equitable healthcare access, cancer and chronic disease support, and preventive health education, as well as hunger relief, community gardening, dental and transportation services, and resources for underserved families. Together, they are working to remove barriers to care, reduce preventable conditions, and empower individuals and communities of all ages and backgrounds to achieve better health outcomes. Photo courtesy of Medical Motor Service of Rochester and Monroe County, Inc. Description: MMS driver speaking to a Wegmans shopper. GGWNY staff; Lincoln Memorial Church Community Garden and lead gardener Diane Learn more about our recipients and the impact they make within their communities below. Community Solutions Challenge Advocates for Women’s Health, Inc. Advocates for Women's Health exists to provide access to high quality prenatal care and gynecology care to lower-income communities in and around Fresno, CA. They operate a nonprofit OB/GYN clinic located in Fresno. American Rescue Workers (ARW) ARW is a faith-based, non-profit organization providing homelessness and hunger prevention services in Central PA since 1934. ARW cares holistically for men, women, and children who find themselves facing food insecurity, and emergency situations that may lead to homelessness, or an actual homeless crisis, by providing shelter and social services. ARW serves people no matter their faith, regardless of faith. Asian Americans Advancing Justice Southern California (AJSOCAL) AJSOCAL is a social justice organization that protects and strengthens the rights and dignity of AAPI communities, especially those that are most disadvantaged. Byrd Cancer Education and Advocacy (BCEA) BCEA’s mission is to effectively assist individuals battling cancer by connecting them to vital support and resources. BCEA ensures that all relevant information reaches those in need, guiding them towards the resources necessary to fight their battle against cancer. Catholic Charities of the Diocese of Santa Rosa Catholic Charities of the Diocese of Santa Rosa creates access to opportunities for self-sufficiency by providing innovative and compassionate services to people of all backgrounds, beliefs and cultures. Chosen Hearts Chosen Hearts’ mission is to rebuild lives and restore hope by fostering a sense of community and creating lasting, positive change. Columbia Student Medical Outreach The Columbia Student Medical Outreach Program (CoSMO) Clinic is the oldest and largest student-run free clinic at the Vagelos College of Physicians and Surgeons at Columbia University. At its core, CoSMO is guided by the belief that all people—regardless of immigration or insurance status—deserve access to high-quality, equitable medical care. Eagle’s Nest Community Kitchen and Resource Center and Mobile Pantry Eagle’s Nest Community Kitchen, Resource Center and Mobile Pantry’s mission is to empower underserved and rural communities through hands-on STEM education grounded in sustainable agriculture. By combining mobile workshops, community gardens, and mentorship, they deliver accessible training in science, technology, engineering, and math that builds practical skills, advances food security, and fosters environmental stewardship. Through collaborative partnerships and by honoring local knowledge, they cultivate resilient communities and inspire the next generation of agricultural innovators. eClose Institute eClose Institute’s mission is to make medically relevant scientific discoveries using an education platform that embraces equality and empowers participants to contribute ideas, life experience and experimental data to improve disease treatment. Equal Hope Equal Hope is an organization dedicated to saving lives and improving quality of life by eliminating health inequities. This organization challenges the status quo in striving to understand the context of people’s lives and the barriers they experience to help them achieve better health outcomes for their lives. Through research, quality assessment and improvements, advocacy, education, and patient navigation, they approach health holistically to achieve sustainable outcomes and true health equity. Food For Free Committee Food For Free improves access to healthy food through establishing innovative programming and partnerships to overcome barriers and strengthen the community food system. They believe that access to healthy food is a fundamental right. Grassroots Gardens of Western New York (GGRWNY) The missions of GGRWNY is to share knowledge, powers, and resources to grow health food, heal systemic harm, and strengthen neighborhood connections through community gardens. Greater Providence YMCA (GPYMCA) GPYMCA builds healthy spirit, mind, and body for all, through inclusive programs and relationships grounded in core values of caring, honesty, respect, and responsibility. Programs are intentionally designed to close equity gaps in health, education, and wellness. GPYMCA serves individuals and families across all life stages and income levels, including medically vulnerable and underserved populations. Hearts of Valor INC Hearts of Valor’s missions it to keep the heart pumping through advocacy, collaboration, education, and support. Ibn Sina Foundation Ibn Sina Foundation ensures the health of the community by providing integrated, preventive, and primary care in a clinical setting through the dissemination and application of health-related knowledge, thereby enhancing the quality of life for future generations. India Home India Home is a non-profit organization dedicated to addressing the needs of and empowering the South Asian and Indo-Caribbean senior immigrant community in New York City through culturally competent services. At India Home’s centers, seniors find community and resources through a diverse range of programs and activities. Programs include congregate meals, creative aging programs, case management programs, and educational talks on health, nutrition, financial safeguards and elder law. La Colaborativa La Colaborativa empowers the Latinx community, enhancing social and economic health, and holding institutional decision-makers accountable. Lancaster County Food Hub At the heart of the Lancaster County Food Hub’s (LCFH) work is a strong commitment to meeting basic human needs, fostering respectful relationships, and connecting neighbors with supportive services in a nurturing and welcoming environment. Guided by their vision of a Lancaster County where every individual is supported and empowered to live with dignity and stability, they strive to not only provide immediate relief but also to create pathways to lasting self-sufficiency. Maryland Foundation of Dentistry (MFD) MFD is dedicated to improving oral health outcomes and preserving dental function for one of the state’s most vulnerable populations: adults with intellectual, physical, and/or developmental disabilities who are unable to afford the cost of dental care. Maternity Care Coalition (MCC) The missions of MCC is to improve the health and well-being of pregnant women and parenting families and enhance school readiness for children 0-3. MCC achieves this through direct service, advocacy, and research, in collaboration with individuals, families, providers, and communities. Medical Motor Service of Rochester and Monroe County, Inc. Medical Motor Service of Rochester and Monroe County’s mission is to provide specialized transportation for community organizations, as well as individuals with disabilities and special needs to improve their independence and quality of life. Milwaukee Consortium for Hmong Health (MCHH) MCHH’s mission is to create a thriving and healthy Southeast Asian and Hispanic community by empowering families through education and screenings. MCHH utilizes established community health workers and focuses on addressing health disparities related to cancer and chronic disease among the Hmong, Bumese, Karen, Karenni, Lao, and Hispanic populations living in Milwaukee, WI and other areas if needed. Mission Hospice and Home Care Mission Hospice and Home Care is delivering compassionate support and exceptional care in the home for individuals and communities, guiding them with choice and dignity to navigate significant care decisions. North Alabama AHEC (NAAHEC) The mission of the NAAHEC is to improve healthcare access, quality, and equity in rural and underserved communities across North Alabama. They strengthen the health workforce - particularly through the development of community health workers by providing comprehensive training, resources, and advocacy. By fostering strong community partnerships and promoting healthcare literacy, NAAHEC aims to address disparities, improve outcomes, and cultivate a healthier future for North Alabama. Our Neighbors’ Table Hunger comes in many forms. Our Neighbors’ Table is committed to establishing a community that provides for the whole person with nourishing food, kindness and dignity. Panhandle Breast Health Panhandle Breast Health works to decrease breast cancer deaths by providing education and reducing financial barriers to increase screening rates. Pitney Meadows Community Farm Founded in 2026, Pitney Meadows Community Farm’s mission is to celebrate and explore agricultural education, healthy food production, and recreation. Located on 166 acres in the heart of the city of Saratoga Springs and preserved in perpetuity as a working farm, Pitney Meadows is a unique resource. Prince William County Community Foundation (PWCCF) PWCCF’s mission is to create a stronger, healthier, and more connected community by addressing critical needs in food insecurity, health & wellness, scholarship, and philanthropy. PWCCF is committed to empowering individuals and families through equitable access to nutritious food, comprehensive healthcare, educational opportunities, and community-driven support. By fostering partnerships and promoting sustainable solutions, PWCCF aims to enhance the quality of life for all, ensuring a brighter future for every member of their community. Raytown Christian Church (Raytown Summer Lunch Ministry) Raytown Summer Lunch Ministry’s mission is to provide nutritious and kid-friendly meals to children during the summer months when they are not in school and receiving school meals. Regents of the University of California, Davis UC Davis Health is improving lives and transforming health care by providing excellent patient care, conducting groundbreaking research, fostering innovative, interprofessional education, and creating dynamic, productive partnerships with the community. RSVP Volunteers RSVP Volunteers creates and runs unique community programs powered by skilled volunteers to advance education and wellness for all ages and strengthen nonprofits through capacity-building and volunteer services. Second Harvest Food Bank of Orange County Second Harvest Food Bank of Orange County, in collaboration with partners, provides dignified, equitable and consistent access to nutritious food, creating a foundation for community health. The Icla da Silva Foundation The mission of the Icla da Silva Foundation is to save the lives of patients whose only cure is a bone marrow transplant by providing financial, emotional, and logistical support to remove barriers to treatment. There With Care of the Bay Area Founded in 2012, the mission of There With Care of the Bay Area is to provide a wide range of meaningful and fundamental services to children and families during the critical phase of a medical crisis. Universal Community Health Center Universal Community Health Center’s mission is to provide quality and accessible healthcare to under-served communities and to provide a patient centered model of care to empower communities towards wellness. West Cancer Foundation West Cancer Foundation breaks through barriers to cancer care and improves patient outcomes by providing accessible patient resources, early detection and education, and community-based research. Westside Family Healthcare Westside Family Healthcare’s mission is to improve the health of communities by providing equal access to quality healthcare, regardless of ability to pay. National Strategic Collaborations Foundation of Asthma and Allergy Impact Rescue (AAIR) The mission of The Foundation for Asthma and Allergy Impact and Rescue (AAIR) is to make sure that every child is rescued at school, healthy at home, and connected to care. Family Reach Foundation Family Reach is a nonprofit that provides non-medical financial support to families facing cancer. Cancer treatment requires more than medicine — families need a roof over their heads and food on their tables to survive. If a family can’t meet these basic needs, cancer treatment takes a back seat. They work with patients, providers, and community organizations to challenge the systems that force families to choose between their health and their home. LUNGevity Foundation LUNGevity Foundation is transforming what it means to be diagnosed and live with lung cancer through research, advocacy, and community. This mission brings them closer to their vision: a world where no one dies of lung cancer. Association of Black Cardiologists The Association of Black Cardiologists is dedicated to preventing and treating cardiovascular disease, including stroke, through education, research, advocacy, and community engagement, striving for optimal health for all by eliminating disparities. Cholangiocarcinoma Foundation (CCF) The Cholangiocarcinoma Foundation’s (CCF) mission is to find a cure and improve the quality of life for those affected by cholangiocarcinoma (bile duct cancer). Founded in 2006, in Salt Lake City, UT, by a family who lost a loved one to cholangiocarcinoma, CCF has grown to become the leading global resource in research, education, and public awareness. ZERO Prostate Cancer Zero Prostate Cancer’s mission is to improve and save lives from prostate cancer through advocacy, awareness, education, and support. GO2 for Lung Cancer GO2 for Lung Cancer relentlessly confronts lung cancer on every front, every day, for everyone. As the nation’s leading lung cancer advocacy organization that was founded by patients and survivors, they are dedicated to increasing survival and quality of life for those at risk, diagnosed, and living with lung cancer. National Minority Quality Forum The National Minority Quality Forum (NMQF) is a national 501(c)(3) with a mission to reduce patient risk for all. Young Survival Coalition (Breast) Young Survival Coalition supports the young breast cancer community and ignites global collaboration to improve quality of life worldwide. Black Women’s Health Imperative Black Women’s Health Imperative’s mission is to solve the most critical health issues that Black women and girls face through innovative programs, transformative research, and lifesaving policies.
Upper Iowa University launches 90-credit degree in business administration
Upper Iowa University has launched its first 90-credit bachelor's degree pathway as state universities work to establish their own.
That dry, bitter taste may be waking up your brain
New research suggests the astringent sensation caused by flavanols could act as a direct signal to the brain, triggering effects similar to a mild workout for the nervous system. In mouse experiments, flavanol intake boosted activity, curiosity, learning, and memory—despite these compounds barely entering the bloodstream. The key appears to be sensory stimulation: the taste itself activates brain pathways linked to attention, motivation, and stress response, lighting up regions involved in arousal and memory.
Sources: Lakers won't pursue 'single pathway' this summer
Will it be Giannis Antetokounmpo or bust this summer for the Lakers?
Windhorst: Lakers, Draymond Green have mutual interest
ESPN's Brian Windhorst says there is a pathway for Draymond Green to join the Lakers very soon.
New triple-drug treatment stops pancreatic cancer in its tracks, a mouse study finds
By targeting three key growth pathways at once, researchers eliminated pancreatic tumors in multiple mouse models and prevented the cancer from returning, a promising step toward overcoming treatment resistance.
cbdMD Strengthens Regulatory Science Platform to Support Emerging Regulatory Cannabinoid Evaluation Pathways
cbdMD, Inc. (NYSE American: YCBD), a leading innovator in hemp-derived wellness products, today announced a strategic initiative to integrate and expand its regulatory science, safety, and intellectual property assets to establish a differentiated cannabinoid compliance and evidence platform aligned with evolving federal healthcare evaluation frameworks, including emerging CMS and CMMI innovation initiatives.
California’s health care workforce crisis is a policy choice
“California should redouble our own state investments in health care workforce pathways and financial support for students.”
Cairn and Peak Capture the Thrill of Climbing Mountains
With infinite pathways and incredible tension, video games like Cairn and Peak are recreating the activity’s emotional highs and lows.
Internal review contradicts Trump administration on Alex Pretti shooting : The NPR Politics Podcast
An initial internal review into federal immigration officers’ fatal shooting of Alex Pretti in Minneapolis last weekend contradicts the description of the incident by Homeland Security Secretary Kristi Noem. We discuss President Trump’s shifting messages on immigration policy and how his administration’s efforts to restrict legal immigration pathways are changing the political environment. This episode: senior White House correspondent Tamara Keith, immigration policy correspondent Ximena Bustillo, and senior political editor and correspondent Domenico Montanaro.This podcast was produced by Bria Suggs and Lexie Schapitl, and edited by Rachel Baye.Our executive producer is Muthoni Muturi.Listen to every episode of the NPR Politics Podcast sponsor-free, unlock access to bonus episodes with more from the NPR Politics team, and support public media when you sign up for The NPR Politics Podcast+ at plus.npr.org/politics.
First Brands Group Commences Wind Down of North American Brake Parts Inc., Cardone, and Autolite Business Units
ROCHESTER HILLS, Mich., January 26, 2026--First Brands Group, LLC ("First Brands" or the "Company"), a leading global supplier of automotive parts, announced that it has commenced a wind down of certain of its North American business operations, including its Brake Parts Inc., Cardone, and Autolite brands. First Brands’ remaining business units continue to operate while the Company assesses pathways to transition these operations to new ownership.
Outdoor learning at Burke Lake shows students science career pathways
Environmental science and policy professor Cynthia Smith organizes outdoor education programs for seventh graders across the county, diving into the importance of hands-on research and environmental conservation.
Health Rounds: How obesity leads to uncontrolled inflammation discovered
Researchers say they have finally discovered the pathway by which obesity causes runaway inflammation that can lead to a host of health issues such as diabetes and liver disease.
NCAA adds flag football to Emerging Sports for Women program
Women's flag football has been added to the NCAA Emerging Sports for Women program, effective immediately, creating a pathway toward NCAA championship status as schools work toward the 40-sponsor threshold.
Mapping the science–technology translational landscape in biomedicine
Nature Biotechnology - A systematic, prospective analysis of the interplay between science and technology in biomedicine can illuminate the pathway for translating scientific insights into tangible...
What Can You Do With an Environmental Science Degree?
This guide breaks down environmental science careers, job outlook, skills, and education pathways.
Sports for People and Planet
The $2.3 trillion global sports economy is experiencing robust growth, with annual revenues projected to reach $8.8 trillion by 2050. However, factors such as rising levels of physical inactivity and escalating environmental challenges could erode up to $1.6 trillion in annual revenue by mid-century. The World Economic Forum, in collaboration with Oliver Wyman, has developed this insight report to highlight the urgent social and economic imperative for coordinated public–private action to secure the sector’s long-term resilience, presenting transformative, multistakeholder pathways and innovative case studies.This approach ensures that the future of sport remains competitive and inspiring, while also being sustainable and inclusive for people and the planet alike.
Scientists find a natural sunscreen hidden in hot springs bacteria
Researchers studying cyanobacteria from hot springs in Thailand have discovered a new natural UV-blocking compound with impressive antioxidant power. Unlike conventional sunscreens, it’s biocompatible and potentially safer for both people and the environment. The molecule is produced only under UV and salt stress and uses a unique biosynthetic pathway never seen before. This could help drive a new generation of eco-friendly sunscreens and skincare products.