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U.S. Department of Health and Human Services (HHS) Recommends Science-Based Thresholds to Target Dangerous Enhanced Kratom Products

Kratom products credit: CDPH DEA takes action based on updated recommendation from HHS October 11, 2026 - WASHINGTON - On Friday, the U.S. Department of Health and Human Services relesed the following: The U.S. Department of Health and Human Services (HHS) provided a new recommendation to the Drug Enforcement Administration (DEA) that establishes science-based thresholds for 7-hydroxymitragynine (7-OH) and mitragynine pseudoindoxyl (MGPI), potent opioid compounds associated with products marketed as kratom. The Department of Justice today announced that DEA issued new Notices of Intent reflecting HHS’ updated scientific analysis and recommendations, including a new Notice of Intent for 7-OH and MGPI incorporating HHS’ recommended concentration and ratio thresholds. Following a review of available scientific data and comments, HHS Assistant Secretary for Health Admiral Brian Christine, M.D., recommended that DEA use concentration or ratio-based thresholds to determine which products containing 7-OH and MGPI are subject to Schedule I control for purposes of temporary scheduling of these substances under the Controlled Substances Act. The recommendation is designed to target concentrated or chemically altered products while distinguishing them from natural botanical kratom products, which may contain trace amounts of 7-OH and MGPI. “We are drawing a clear line between natural kratom and dangerous, enhanced opioid products,” said HHS Secretary Robert F. Kennedy, Jr. “We listened to the public, followed the science, and developed a clear recommended threshold for temporary scheduling that targets concentrated 7-OH and MGPI without sweeping natural botanical kratom into Schedule I. The Trump Administration will continue taking decisive action against dangerous products that fuel addiction while making sure our policies are grounded in rigorous science.” Under the recommendation, 7-OH and MGPI would be controlled in Schedule I for purposes of temporary scheduling when either substance alone, or their combined amount when both are present: Exceeds 1 milligram per gram in solid powders, encapsulated material, or other solid forms, or exceeds 1 milligram per milliliter in liquid preparations; or When the mass of mitragynine present divided by the mass of 7-OH, or MGPI, or the combined amount of 7-OH and MGPI if both present, is less than 100. The ratio-based approach reflects the alkaloid composition of natural kratom products and provides a way to identify products intentionally enhanced or concentrated with 7-OH or MGPI. Available scientific data indicate that 7-OH occurs naturally in botanical kratom at relatively low or trace levels, while some evidence reviewed by FDA suggests MGPI may also occur at trace levels in some natural or kratom-derived products. FDA's scientific review found that 7-OH is substantially more potent than morphine in preclinical studies, with available data indicating approximately two to nine times greater potency depending on the study. FDA also identified evidence supporting a meaningful risk of opioid-like physical dependence and withdrawal from MGPI. “Our recommendation gives DEA a scientifically supportable framework to distinguish natural botanical kratom from products that have been concentrated or manipulated to deliver dangerous levels of potent opioid compounds,” said Assistant Secretary for Health Admiral Brian Christine, M.D. “This approach allows us to focus on the products that pose the greatest threat to public health.” In July 2025, following an FDA scientific and medical evaluation, HHS recommended that 7-OH above a specified threshold be placed in Schedule I of the Controlled Substances Act. In July 2026, DEA announced its intent to temporarily schedule 7-OH above a specified threshold, and HHS simultaneously sought public comment on the proposed threshold. DEA subsequently temporarily placed MGPI and two synthetic 7-OH derivatives, MGM-15 and MGM-16, in Schedule I. Since then, questions have emerged about how scheduling could affect natural botanical kratom products potentially containing trace amounts of MGPI. The new HHS recommendation responds to those concerns by providing DEA with a more precise threshold based on both the concentration of 7-OH and MGPI and their relationship to mitragynine, the predominant alkaloid in kratom. HHS and FDA will continue working with DEA to protect Americans from dangerous concentrated and synthetic opioid products while ensuring federal policy is grounded in the best available science. Source: HHS

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Oct 11 • 6:20 AM EDT • Science • goldrushcam.com
Sweating the details: Sauna's potential health benefits draw scientists' interest

A group of international researchers is pushing to rigorously study the potential health benefits of sauna and other heat therapies. They hope to bring scientific legitimacy to the age-old practices.

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Oct 11 • 6:00 AM EDT • Science • npr.org
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Sweating the details: Sauna's potential health benefits draw scientists' interest

A group of international researchers is pushing to rigorously study the potential health benefits of sauna and other heat therapies. They hope to bring scientific legitimacy to the age-old practices.

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Oct 11 • 6:00 AM EDT • Health • npr.org
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Clover Health (CLOV) Stock Looks Reasonable Despite New 5 Star Ratings

Clover Health Investments has seen sharp swings in its share price in recent years, and the stock closed at US$4.79 most recently. With the business in the spotlight after new Medicare plan ratings, the question for investors is whether that price can be explained by its sales. The stock has delivered a very large 3 year return of about 365.0%, which puts a lot of weight on whether current revenue levels and future top line potential can support today’s valuation. Clover Health’s Medicare...

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Oct 10 • 10:32 PM EDT • Health • simplywall.st
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Trust in science falls as COVID-era confidence fades, global survey finds

The retreat has potentially far-reaching consequences for public health as vaccination rates decline and preventable diseases resurge.

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Oct 10 • 8:48 PM EDT • Science • japantimes.co.jp
AI is among 17 potentially ‘catastrophic threats’ that researchers say require targeted action

More than a dozen “interconnected catastrophic threats” pose significant risk to global health and wellbeing through the remainder of the 21st century, researchers say – including the potential for extinction. But targeted action from world leaders can help avoid worst-case scenarios.

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Oct 10 • 7:59 PM EDT • Health • cnn.com
Global Experts Identify 17 “Catastrophic” Threats To Human Health This Century – Including 2 With “Extinction Potential”

The commission outlines a 75-year outlook for the threats, taking us the year 2100.

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Oct 10 • 7:05 PM EDT • Health • iflscience.com
Erie County Department of Health reports potential diphtheria exposure in West Seneca schools

Erie County Department of Health reports potential diphtheria exposure in West Seneca schools

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Oct 10 • 6:44 PM EDT • Health • wivb.com
Erie County Department of Health reports potential diphtheria exposure in West Seneca schools

BUFFALO, N.Y. (WIVB) — The Erie County Department of Health has confirmed a travel-related case of bacterial illness diphtheria, with schools in the West Seneca Central School District being identified as potential exposure sites. According to the district, notifications have been sent to families at Clinton Primary, Northwood Elementary, Winchester-Potters Elementary & East Middle School. […]

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Oct 10 • 3:30 PM EDT • Health • wivb.com
Marvin Harrison Jr. may be on move soon

Cardinals WR Marvin Harrison Jr. to be held out of Week 5 because of potential trade

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Oct 10 • 1:20 PM EDT • Sports • sports.yahoo.com
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Time capsule: As woodstove season approaches, elucidating the differences in hardwood and softwood

From density to molecular structure, potential firewood offers much to consider.

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Oct 10 • 1:07 PM EDT • Science • adn.com
Survey results: Fans split on the Giants’ playoff potential

Giants fans don’t think their team can win the division, but give them better odds at being a Wildcard.

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Oct 10 • 12:00 PM EDT • Sports • sports.yahoo.com
NBA insider reveals potential Warriors' Kristaps Porzingis return timeline for unknown health issue

Kristaps Porzingis has not been to training camp after suffering an undsiclosed health issue. An NBA insider may know when the veteran center will come back.

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Oct 10 • 11:28 AM EDT • Health • sports.yahoo.com
Jim Cramer Breaks Down the Complicated Story Behind CVS Health’s (CVS) Decline

During the October 6 episode of Mad Money, Jim Cramer examined whether CVS Health Corporation’s (NYSE:CVS) turnaround still has room to run after the stock’s sharp retreat from its summer highs. CVS ranked ninth among 10 stocks screened for a potential bear market. The criteria behind its inclusion offer another way to assess the turnaround […]

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Oct 10 • 11:26 AM EDT • Health • finance.yahoo.com
Raiders Urged to Make Trade to Improve 1 Key Position

The Las Vegas Raiders have emerged as a potential candidate to pursue a wide receiver before the NFL trade deadline, but their early-season success may not change the team’s cautious approach. Despite opening the campaign with a 3-1 record, the franchise must decide whether adding an established pass catcher is worth sacrificing valuable draft capital. […] The post Raiders Urged to Make Trade to Improve 1 Key Position appeared first on Gridiron Heroics.

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Oct 10 • 7:36 AM EDT • Sports • sports.yahoo.com
Juventus and Roma are interested in new Italy star

Issa Doumbia has emerged as a potential transfer target for Juventus after receiving his first call-up to the Italian national team under Roberto Mancini during the September and October international...

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Oct 10 • 7:00 AM EDT • Sports • sports.yahoo.com
China unveils smart robot designed to help farmers breed better strains of wheat

The prototype device was designed to use a ‘vast amount of breeder experience’ when assessing crops for their breeding potential.

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Oct 10 • 5:11 AM EDT • Science • scmp.com
Sarasota County commissioner’s husband paid $42K by lobbyist for developers

The financial relationship between Tallahassee lobbyist and Sarasota County Commissioner raises concerns about potential conflicts of interest under Florida ethics law.

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Oct 10 • 5:00 AM EDT • Politics • wusf.org
These lawmakers want to head off a potential post-election crisis

A bipartisan effort is underway in Congress to avert a constitutional crisis, where Republicans don't seat Democrats, if they win the chamber.

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Oct 10 • 5:00 AM EDT • Politics • washingtonpost.com
Friedkin place focus on Roma amid Everton sale

The Friedkin family has put Everton, acquired in 2024 through its holding company, up for sale. According to Il Messaggero, this decision is linked both to economic reasons and to the potential diffic...

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Oct 10 • 4:01 AM EDT • Sports • sports.yahoo.com
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Detroit Pistons See Potential With Ausar Thompson At PG

With one preseason game in the books, the Detroit Pistons already have an exciting wrinkle to explore with Ausar Thompson logging point guard minutes

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Oct 9 • 10:20 PM EDT • Sports • sports.yahoo.com
MLB Insider Links Guardians' Steven Kwan To Padres

A.J. Preller could pursue a blockbuster trade for Cleveland’s Gold Glove outfielder, potentially shifting Fernando Tatis Jr. in the lineup to create a terrifying new offensive core.

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Oct 9 • 9:00 PM EDT • Sports • sports.yahoo.com
Nets’ Wolf, Traoré Taking Sophomore Leaps in Preseason

Explosive driving and elite playmaking from Brooklyn's rising sophomores signal a potential bench revolution, transforming last season's developmental growing pains into a formidable second-unit strength.

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Oct 9 • 5:50 PM EDT • Sports • sports.yahoo.com
Trump Says He Will Import Russian Diesel Fuel Amid High Prices

President Trump said Russia had agreed to ship potentially millions of tons of diesel fuel in the coming months. But Russia has an ongoing ban on exporting diesel.

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Oct 9 • 3:57 PM EDT • Politics • nytimes.com
Netflix’s Summer of Bummer

(Welcome to the Entertainment Strategy Guy, a newsletter on the entertainment industry and business strategy. I write a weekly Streaming Ratings Report and a bi-weekly strategy column, along with occasional deep dives into other topics, like today’s article. Please subscribe.) Today, I’ve got a guest post from longtime friend of the newsletter, Brandon Katz. I’ve been trying to find time all summer to look at Netflix’s straight-to-streaming film slate, but between a pre-planned trip and Nielsen moving up their streaming data timeline, I’ve been swamped. So I reached out to Brandon, one of my favorite fellow analysts, to write about it. And I feel like he captured the tone and data focus of the newsletter perfectly. You can connect with Brandon on LinkedIn and Twitter. Enjoy! Don’t worry, folks. You’re in safe hands with me. To ease any anxieties about an interloper in ESG’s domain, I’ll start by stealing one of his best framing devices: headlines. Box office flops are covered in the same way the Teenage Mutant Ninja Turtles eye pizza: with cartoonish insatiability. I would know. I’m a former reporter who wrote nearly identical headlines: Yet, intentionally or not, streaming misses get treated with kids gloves, filtered through a rosy lens: In the last six years, U.S. streaming viewership has become nearly as transparent as the box office, but the data often arrives weeks later, in a number of less intuitive metrics, and with nary an official budget to be found. This plays into the Wall Street-whispering narratives major streamers have been cultivating for years. They get a pass in a way that theatrical studios simply don’t. Subscribe Netflix’s Summer Slate Not a single Netflix original film released between May and August this year opened above 20 million U.S. TV hours, per Nielsen. That benchmark usually serves as the EntStrategyGuy’s floor for a streaming hit on Netflix. None of these films enjoyed a hit-cementing single week of 20-plus million hours during their runs. Netflix’s two best films were true crime docs, Maternal Instinct (16.5 million hours) and The Crash (19.7 million), the best overall week for a film this summer. Great for most other streamers, but not necessarily what we’re used to seeing from Netflix. For an overly-dramatic comparison, Happy Gilmore 2 opened last summer to around 47 million hours (celebrity cameos, baby!). Zooming out, the picture looks even worse. In 2026, Netflix’s five biggest scripted summer films posted the lowest average (28.6 million hours) and median (28.8 million hours) eight-week viewership totals of the past four years. Now, it’s unrealistic and unfair to expect Netflix to deliver a _KPop Demon Hunters-_sized hit every year. But it’s also not ideal to see the size of their hits shrinking over the last few summers. Let’s quickly run through some of the notable summer misses. Jennifer Lopez and Brett Goldstein’s perfectly fine romcom, Office Romance, fell off the charts after 20 million hours in its first two weeks. Top films usually last for four-plus weeks. Starry titles ideally don’t decay that fast either. Homegrown star Millie Bobby Brown couldn’t prevent the snappy Enola Holmes franchise from diminishing returns. At 14.3 million U.S. hours, the third film posted roughly half of what the first two films did in their first two weeks. What’s on Netflix calculated that per-day global views were down nearly 60% from the second movie. The Whisper Man did okay with more than 36 million hours over its first four weeks. But I expected a little more juice from a film featuring Robert De Niro, Michelle Monaghan, and Adam Scott. Kevin Hart’s Ladies First collected just 11.2 million hours total across two weeks. That’s a big miss for one of Netflix’s go-to stars. Plopping into the same bucket are Sunny Sandler’s Don’t Say Good Luck (10.3 million in two weeks) and John Cena’s Little Brother (17.5 million). Meanwhile, English-language originals Color Book (June 19), In the Hand of Dante (June 24) and Heartstopper Forever (July 17) never sniffed Nielsen’s Top 10 at all, despite needing only 2 to 5 million hours to land in the top ten most weeks. (By my count, eleven English-language scripted original films released between May and August did chart). It’s only fair to mention that Swapped (1-May) posted nearly 42 million U.S. hours over five weeks (the longest Netflix original run this summer) and is currently their eighth most-watched English-language film ever worldwide. Remarkably Bright Creatures (37 million, 4 weeks) and Voicemails for Isabelle (27 million, 4 weeks) weren’t bombs either. Still, overall, I think it’s fair to say this was a quieter summer season than we’re used to seeing from the market-leader. You might not realize that given the language commonly used in public analysis. The Twist Despite the starkly black-and-white tone of the coverage, here’s the twist: when many box office bombs arrive on streaming, their viewership looks a whole lot like many of Netflix’s supposedly successful summer releases. Hmm, where have we heard that one before? Masters of the Universe topped out at $65 million stateside against a $170 million budget_._ I’ll admit, Skeletor ripping sleeveless curls as a gym bro and bodyslamming Adam’s co-workers was funny. But, much to the chagrin of my bank account, my laughter doesn’t launch franchises. Yet the He-Man reboot opened to 19.6 million hours (from a Wednesday five-day opening instead of just one weekend), on par with Hoppers on Disney+ (19.4 million). It put up nearly 47 million hours over its first six weeks, bigger than all of Netflix’s summer releases. Pretty darn healthy and likely to land among the 25 most-watched movies on streaming this year. Sticking with Amazon, The Sheep Detectives just barely broke even at the box office with $133 million worldwide (and only $66 million domestic). I never expected cloven-hooved, cud-chewing mammals to be able to bring me to tears. Yet that’s exactly how I found myself at the end of this surprisingly affecting movie (#NoShame). It was likely the unexpected quality in a family-friendly film that powered its streaming over-performance. Sheep Detectives delivered a solid run for Prime video netting 26.2 million hours! How about franchise IP? Star Wars: The Mandalorian & Grogu had the lowest opening ($81 million) and lowest-grossing Disney-era live-action Star Wars film ($178 million domestic). One day before release, its Heat score (19.8%)—audiences who list their interest as a 7/7—fell behind blockbusters Wicked (21%), Superman (23%), Fantastic Four: First Steps (23%), Michael (23%), Toy Story 5 (26%) and Avatar: Fire and Ash (27%), according to Greenlight Analytics. The urgent enthusiasm just wasn’t there. On streaming, Mando opened to weeks of 12.1 million, 6.1 million and 2.7 million hours (21 million total) over its first three frames. Not the numbers Lucasfilm was hoping for nor the numbers of a streaming hit. But they’re in the same vicinity as some Netflix summer releases with $345 million at the global box office to offset a smidgen of the pain. Final Thoughts So why oh why does this nuance gap exist? Four key reasons: Data Literacy: A “$100 million opening” just makes sense. After decades of box office reporting, even casual movie fans are well-versed in the benchmarks of hits and home runs. There’s an immediate shorthand. But “16.5 million” hours doesn’t land nearly as cleanly. Despite leaps of progress, the streaming ratings era is still in its infancy compared to theatrical. The EntStrategyGuy and I met thanks to a late 2010s group chat of data nerds hungry to find a shred of certainty in nebulous streaming performance. I’m not surprised to see “No. 1 on Netflix” still getting misconstrued out in the wild. Timing: By Friday morning, we have the box office’s Thursday night previews totaled, allowing us to better project the weekend’s expectations. From there, ticket sales are reported daily. By Sunday, the film’s fate is usually finalized, at least in terms of public perception. In streaming, Nielsen recently improved its delay to…two weeks. The medium isn’t forced to contend with instant gratification as harshly. Financials: Theatrical film budgets are a mere Google away. Profit and loss is calculated in the cold and unforgiving naked light of day for all to see. But finding the vast majority of streaming exclusive movie budgets requires the forensic investigation skills of a Criminal Minds detective. Also, it’s very difficult to calculate how much revenue/value a straight-to-streaming films provides a streamer. This is why there are so few stories about streaming original movies “losing X amount of money”. On top of that, marketing budgets are far greater for theatrical movies than streaming exclusive movies, which leads to earlier and better awareness. This then translates to a wider pool of potential interest. Narrative Control: Netflix is the only major streaming service to publish weekly first-hand viewership data and annual engagement reports. Naturally, some headlines borrow their first-hand framing**.** Other streamers benefit from their comparative lack of transparency. They may occasionally announce vague performance platitudes such as Apple TV’s Mayday becoming its “biggest film debut on the platform to date over its first 18 days,” and that it ranked No. 1 with left-handed viewers in its first weekend. (Fine, I made up that second one). But, for the most part, they keep first-hand viewership shrouded in mystery to avoid bad press. Especially for outlets that demand multiple articles per day from their writers, it’s an easy (and understandable) way for some reporters to hit their daily article quota by just repeating what the streamers have told them. TL:DR version: Streaming-exclusive movies are asked to do different things than theatrical movies, but that doesn’t mean they should escape judgment. Both still need to draw enough eyeballs to justify their cost within the proper performance contexts. The more cleanly we can inject a little nuance into streaming analysis, the better we’ll understand the audience and content trends that drive this industry. And that’s what all of this is really about: knowing what audiences actually want! Brandon Katz is the Director of Insights & Content Strategy at Greenlight Analytics where he focuses on evaluating the ever-fluid media landscape to unearth understanding, opportunity and value. Greenlight Analytics is the entertainment intelligence consulting company redefining how Hollywood finds, understands, and activates audiences. Prior to joining Greenlight Analytics, he served as the senior entertainment industry strategist at Parrot Analytics, and as a full-time entertainment industry reporter covering the Xs and Os of Hollywood, most notably with TheWrap and the Observer.

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Oct 9 • 3:32 PM EDT • Entertainment • entertainment.substack.com
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Stanford Scientists Identify Enzyme That May Promote Cartilage Regeneration in Arthritis

Stanford researchers identified an enzyme that may restore cartilage repair signals in arthritic joints, offering a potential drug target backed by mouse and human tissue results.

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Oct 9 • 2:00 PM EDT • Science • yahoo.com
‘A Latino problem’: National Democrats clash with Andy Beshear over Texas governor’s race

Kentucky Gov. Andy Beshear hoped being chair of the Democratic Governors Association this midterms year would raise his profile and connections ahead of his expected 2028 run for president. But it’s also created an opening to ramp up pressure on him, with frustrations spilling into the open this week as multiple Texas Democratic members of Congress and national group leaders accused him of putting his book tour and potential 2028 activity ahead of helping Democratic nominee Gina Hinojosa win the Texas governor’s race.

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Oct 9 • 12:19 PM EDT • Politics • cnn.com
RB Leipzig And Leverkusen Join Dortmund In Race For Sporting Talent Flávio Gonçalves

German giants are scouting the Portuguese winger as Sporting CP demands a massive €60 million release clause, forcing the Bundesliga's elite to weigh potential against a record-breaking price.

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Oct 9 • 10:42 AM EDT • Sports • sports.yahoo.com
HHS’s Elimination of Disparate Impact to Determine Discrimination: Potential Implications for Health and Health Care

This brief provides background on Title VI, summarizes the key changes in the 2026 final rule, and discusses the potential implications for racial and ethnic health disparities.

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Oct 9 • 10:28 AM EDT • Health • kff.org
Familiar Face Emerges as Potential Lions Coaching Addition

The Detroit Lions have not decided to make any changes to their defensive coordinator. However, head coach Dan Campbell noted that the team has a bye week, and they are not against potentially adding a defensive advisor from outside the organization to help defensive coordinator Kelvin Sheppard. One name to keep an eye on is […] The post Familiar Face Emerges as Potential Lions Coaching Addition appeared first on HEAVY.

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Oct 9 • 10:06 AM EDT • Sports • sports.yahoo.com
Travel Health Insurance Requirement Implemented

As of October 6, 2026, all travelers to Kenya must obtain travel health insurance through the government-sanctioned provider prior to entry and must present proof of coverage upon arrival. The Electronic Travel Authorisation (ETA) portal (for ETA-eligible nationals) and the eCitizen portal (for non-ETA-eligible nationals) have been updated with this requirement. The insurance costs approximately USD 44 and is valid for one year, including for repeat trips to Kenya during the insurance policy's validity period. Previously, travelers could rely on private or employer-provided health insurance and did not need to provide proof of coverage before entering the country. This change will not affect the above applicants' processing times. However, travelers should obtain the required insurance before traveling to avoid delays or bars to entry. Notably, Tanzania recently adopted a similar mandatory inbound travel insurance requirement, potentially signaling an emerging trend in the East African region.

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Oct 9 • 9:36 AM EDT • Health • fragomen.com
Health policy expert warns California's Medi-Cal spending crisis could drive up insurance costs for families

Paragon Health Institute President Brian Blase discusses California's Medicaid spending, eligibility concerns and the potential impact of higher taxes on privately insured families.

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Oct 9 • 9:28 AM EDT • Health • foxnews.com
Draymond Green Blames Dalton Knecht's Agent for Potential Lakers Cut

Green says Dalton Knecht's agent should have moved him out of Los Angeles once the Hornets trade fell apart.

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Oct 9 • 9:00 AM EDT • Sports • sports.yahoo.com
Blue Jays Insider Gets Candid on Potential Kevin Gausman Return

The Toronto Blue Jays are in offseason mode, and the front office must begin putting its plan to improve the roster into action. After coming within one win of a World Series title in 2025, the Blue Jays missed the playoffs this past season, making changes necessary as they look to get back into contention.Nonetheless, […] The post Blue Jays Insider Gets Candid on Potential Kevin Gausman Return appeared first on HEAVY.

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Oct 9 • 8:01 AM EDT • Sports • sports.yahoo.com
Republican congressman tries to outrun a potential blue wave in New York toss-up seat

Rep. Mike Lawler, R-NY, is in a tight race for re-election in a toss-up district that could help determine control of Congress in November.

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Oct 9 • 5:00 AM EDT • Politics • kgou.org
Everton up for sale? Friedkin Group considering new investment options including the potential sale of controlling stake

The Friedkin Group (TFG) have said they will only entertain interest from parties who they feel are the right stewards to take the club forward; TFG completed their full takeover of Everton in December 2024

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Oct 9 • 4:38 AM EDT • Sports • skysports.com
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Maple Leafs Handed Clear Fight Prediction Before Golden Knights Game

The Toronto Maple Leafs face the Vegas Golden Knights this Thursday, October 8, and the conversation ahead of the game centers not only on possible lineups and outcomes, but also on potential fights.In the latest edition of The Leafs Morning Take, Nick Alberga and Jay Rosehill discussed who could be the first Leafs player to […] The post Maple Leafs Handed Clear Fight Prediction Before Golden Knights Game appeared first on HEAVY.

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Oct 8 • 7:34 PM EDT • Sports • sports.yahoo.com
Progressive ward leader eyes Philly City Council run — and a potential showdown with Mark Squilla

Will Gross, the leader of the South Philadelphia-based 2nd Ward and the owner of OX Coffee in Queen Village, was a prominent opponent of the Center City arena proposal that Squilla supported.

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Oct 8 • 4:39 PM EDT • Politics • inquirer.com
U SPORTS Is Getting An NCAA Boost This Season With

With a new push to potentially limit international players in the NCAA, U SPORTS hockey will become an increasingly enticing option for Canadian players. This season, another group are making the transfer from the NCAA coming to Canada to complete their university women's hockey careers.

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Oct 8 • 3:34 PM EDT • Sports • sports.yahoo.com
Jahsiear Rogers Dismissed From Oklahoma Football Roster

The four-star freshman’s sudden exit leaves a void in the Sooners' developmental ranks, highlighting the program's uncompromising culture despite his promising spring performance and explosive athletic potential

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Oct 8 • 2:42 PM EDT • Sports • sports.yahoo.com
Real Madrid Identify Arsenal's Mikel Merino As New Midfield Option

Mikel Merino has reportedly emerged as a potential transfer target for Real Madrid. The Spanish giants are keen on the versatile midfielder but for now, no talks have taken place between Madrid and Arsenal over a possible deal.

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Oct 8 • 1:24 PM EDT • Sports • sports.yahoo.com
Purdue's College of Veterinary Medicine and One Health Innovation District expansion aims to strengthen workforce pipeline

The dean of Purdue University’s College of Veterinary Medicine says the development of the One Health Research Institute could help address the industry’s labor shortage. Dr. Bret Marsh says the effort is part of a larger statewide push to increase workforce retention. “It’ll be attractive to students, faculty, and staff,” he says. “We’re looking at the potential for […]

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Oct 8 • 11:50 AM EDT • Health • brownfieldagnews.com
Eagles’ Pass Rusher Emerges as Potential Trade Candidate Before Deadline

The Philadelphia Eagles and general manager Howie Roseman have never shied away from being active in NFL trade discussions. Over the years, Roseman has had one of the more aggressive mindsets in the trade market. With the 2026 NFL trade deadline coming up after Week 9, it would not be surprising to hear the Eagles […] The post Eagles’ Pass Rusher Emerges as Potential Trade Candidate Before Deadline appeared first on Gridiron Heroics.

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Oct 8 • 11:39 AM EDT • Sports • sports.yahoo.com
Simple math formula predicts when AI chatbots will go rogue

Most of us now carry in our pockets devices capable of running small AI chatbots. These chatbots have little safety oversight to ensure they don't provide information and answers with the potential to ...

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Oct 8 • 11:00 AM EDT • Technology • techxplore.com
South Korean shipbuilders face potential mass strikes

South Korea’s shipbuilding industry faces mounting headwinds as wage and collective bargaining talks continue, with HD Hyundai Heavy Industries Company Ltd. and Hanwha Ocean Company Ltd.

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Oct 8 • 10:13 AM EDT • Business • businessinsurance.com
New MacBook Pro leak could be very good news for ‘pro’ users

Apple’s new MacBook Pro is coming soon, and the latest leak offers potentially great news for ‘pro’ users worried about its thinner design.

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Oct 8 • 9:40 AM EDT • Technology • 9to5mac.com
Interview: The Fusion Future with Dennis Whyte

MIT nuclear scientist Dennis Whyte on fusion energy and its potential today and tomorrow.

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Oct 8 • 8:01 AM EDT • Science • pbs.org
F1: Teams to discuss potential budget cap changes

In wake of James Vowles' recent criticisms of the budget cap, Formula 1 is set to evaluate changes to the spending limit at the next F1 Commission meeting. As it stands, all teams are required to spend within a maximum limit of $215 million. The budget cap was introduced several years ago to prevent top …

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Oct 8 • 5:03 AM EDT • Sports • sports.yahoo.com
Is Fury v Joshua about meritocratic sporting excellence or just algorithmic celebrity power?

This long-awaited fight is happening exactly as intended: at the sweet spot where commercial potential meets a genuine absence of jeopardy

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Oct 8 • 3:00 AM EDT • Sports • theguardian.com
Eric Morris: Oklahoma State Still Working Through Braylin Presley's Eligibility

Braylin Presley is back at Oklahoma State, but his playing status remains uncertain. Eric Morris says the Cowboys are still working through eligibility questions while Presley faces the challenge of learning a new offense four games into the season. Here's the latest on his potential role.

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Oct 7 • 10:03 PM EDT • Sports • sports.yahoo.com
Chicago business owners push back on proposed ordinance targeting ‘troubled’ businesses

Some aldermen see their ordinance as a potential solution to crack down on criminal activity, and businesses that are accused of enabling criminal activity.

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Oct 7 • 8:29 PM EDT • Business • fox32chicago.com
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AI Makes "Open-Source, Clean Room" Implementations Of Adobe Photoshop & Premier In Rust

As an interesting demonstrator for the power of AI and potentially pressing legal challenges, Claude Code and AI agents have created 'open-source, clean-room reimplementation' versions of Adobe Photoshop, Adobe Premier, and Adobe Lightroom

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Oct 7 • 8:12 PM EDT • Technology • phoronix.com
Who Won August and September: Original Films or Franchises?

(Welcome to the Entertainment Strategy Guy, a newsletter on the entertainment industry and business strategy. I write a weekly Streaming Ratings Report and a bi-weekly strategy column, along with occasional deep dives into other topics, like today’s article. Please subscribe.) I just heard someone say that if you’re reading a pundit or data analyst, and they don’t tell you that they got anything wrong, they’re not a pundit but an “influencer”. I agree with that. You have to tell your audience when you get things wrong, or they won’t (or shouldn’t) trust you as much. Today, we’ve got another edition of “What I Got Right, What I Got Wrong”. In general, I’m patting myself on the back (and patting very hard) about a few things like IP at the box office, LIV golf, horror films, crowdfunding movies, superheroes, and old people going to the theaters. That said, I also made a couple of data mistakes on the streaming bubble popping and HBO’s datecdotes, so I’m not perfect. But first, I need your feedback... Subscribe Follow-Ups: What Should We Call Mid-Budget Movies Which Aren’t Cinematic Enough for Theaters But Are Too Expensive to Make Money on Streaming? After I asked for feedback on what we should call straight-to-streaming films that are too big to pencil out on streaming but not really big enough to resonate in theaters, I got some great suggestions from you all, including... “Moldilocks” from John Aboud “Little Big Indie” from Travis Frick1 “Midflicks” from Jonathan Funke. “Extra-Medium” from Jona Nwuke. (Read the explanation in the footnote.) Between these and Brandon Katz—who suggested “Bermuda Budget Triangle”, “The Platform Gap” and “The Distribution Deadzone”—we’ve got some excellent suggestions. And they’re better than my suggestion, the “Streaming Budget Dead Zone”, so let’s take a poll! The winning entry becomes the new term. Loading... RIGHT: LIV Golf is Fully Bankrupt…Is Anyone Else Next? A few years ago, I was always a bit perplexed at all the articles I’d read praising LIV Golf and their strategy to disrupt the PGA. LIV Golf, a brand new professional golf league, offered PGA stars ten times what they made on the PGA Tour to join their new league. And folks praised this strategy for its initial “success” in that a lot of big names did indeed leave the PGA. Yeah, of course the players came over. LIV Golf paid them so, so, so much more! But LIV Golf hadn’t discovered a way to increase potential revenue. So think about this in basic business terms… They paid much more in costs… …but had no real way to increase revenue. That’s not a strategy! That’s deficit financing. It won’t work unless you bankrupt the competition (and then turn around and pay those same golfers much, much less). It’s not a sustainable strategy and only lasts as long as the company/person/nation backing it decides they’re cool with losing money. For LIV Golf, that meant Middle East oil wealth, in particular Saudi Arabian money. Clearly, the current Iran War has hurt Middle East finances, so they need to trim their more exorbitant spending. And LIV Golf was part of that trimming. This should be a major warning for others. TGL’s parent company, TMRW Sports, just got a $1 billion valuation, despite TGL’s (the indoor golf league) horrible TV viewership of less than half a million viewers per match. Unrivaled, the women’s basketball league, just secured a $650 valuation, despite its horrible TV viewership and a new rival (Project B) entering the scene next year. To relate this to streaming, Hollywood should ask which streamers may have wealthy patrons funding their losses. (Let’s be clear: Google, Amazon and Apple.) Could those patrons lose their appetite? For Amazon, probably not. But Apple has a new boss, so maybe! WRONG: My Analysis of the Streaming Bubble Was Missing a Week I’m going to be congratulating myself a lot today, but I make mistakes too, like this data goof. When I last compiled the data on the decline in TV shows, I was missing one week at the end of June. If you look at the first image, you can see that one week was mislabelled as “July”. Mainly, this image got updated to show a 27% decline, not 29%: This change doesn’t really impact the overall analysis, but it is two percent better. By the way, through the third quarter, the decline increased and it’s now a 30% decrease since 2022. (I’ll write/visualize this in an upcoming article.) But I want you to trust me and my data. Especially these days, when many people are using LLMs that I know are inserting faulty data into their charts, I want to keep earning my audience’s faith. So that’s the accurate data. RIGHT: IP Remains Very, Very Popular In July, I wrote a giant (and I mean giant) article on Backrooms, Obsession, and the box office, going over what we know, what we don’t know about what works in theaters, looking at YouTubers, IP, the horror genre, comic book movies, and a whole lot more. The month of August really tested a lot of my theses and, being honest, mostly supported my arguments. Let’s start with IP. Looking at 8-Aug (the weekend after Spider-Man: Brand New Day came out) to 18-Sep (the weekend that Resident Evil came out, which I think provides a nice bookend to this time period), there were seven films based on pre-existing IP: Resident Evil (2026) ($126 million) Practical Magic 2 ($65 million) _Insidious: Out of the Furthe_r ($65 million) Coyote Vs. Acme ($59 million) Paw Patrol: The Dino Movie ($53 million) Tony ($15 million) Super Troopers 3 ($7 million) Compare those to the notable original films from the past month—I actually could have included more movies, but here are just thirteen, bringing us to an even twenty films—including.... The End of Oak Street ($54 million) Buddy ($26 million) Mutiny ($15 million) By Any Means ($15 million) The Dog Stars ($14 million) Runner ($14 million) One Night Only ($11 million) Hope ($8 million) Spa Weekend ($7 million) The Uprising ($6 million) Teenage Sex and Death at Camp Miasma ($6 million) Onslaught ($3 million) Eli Roth’s Ice Cream Man ($2.8 million) Here’s that in chart form: Five of the top six films in this time period were all based on IP. I made a big chart of films that grossed over $200 million at the box office before Spider-Man: Brand New Day and The Odyssey hit theaters. Let’s update that chart! By the way, if you want to see how I categorized each film—so another bar chart—here it is: I know that many of my fellow critics/pundits/analysts dislike films based on IP and how Hollywood is making so many of them. And I’m sympathetic to this point of view. As I’ve written many, many times before, you need a balance between existing franchises, new IP, and original films. And Hollywood clearly needs to make more films like Resident Evil (a well-made film from a visionary director) and fewer Practical Magic 2’s (which didn’t get critical or customer buzz). But at some point, critics and pundits need to contend with what audiences are telling them: Movie-goers aren’t showing up to original films. Audiences are speaking with their dollars, telling you they want more IP and franchises. You can try to convince studio heads to make fewer IP-based films and franchises, but the data and numbers aren’t there. Instead, critics need to work harder to convince audiences to show up for original films. Aim your ire/concern at the average person, not studio heads.2 Because they’re just making the films that audiences are telling them to make. WRONG: Original Horror Films Didn’t Break Out I’ll be honest, even though I wrote an article casting some skepticism on the horror genre in July, if you asked me to make a prediction, I would have predicted that, in August, a new, original horror film would have blown up. No, seriously, I just assumed that Obsession and Backrooms presaged a change in audience behavior. But none of the buzzy new original horror films from August—Teenage Sex and Death at Camp Miasma, Onslaught (not an action film in spite of the ads), The End of Oak Street, Eli Roth’s Ice Cream Man, or _Buddy—_broke out. To be clear, exactly one of those films (Buddy) had good “ROI”, but again—I try to be specific in my language—none were “popular” in any broad sense of the word. None of them will be “saving” movies theaters like Backrooms or _Obsession_helped save the summer. The new Insidious film and Resident Evil, both based on IP, were far and away the biggest horror films since July. (We’ll see if this changes in October/Halloween season.) RIGHT: Stay Skeptical about Crowdfunding... I’ve long been skeptical about crowd-investing platforms as one of Hollywood’s saviors, mainly because there’s so much hype/buzz. People need to stay more skeptical about more things, explaining both the potential upside but also the downsides. In particular, the media often hypes crowdfunding at the start and never checks in on the actual results after they’ve come in later. And August gave us our first update! _Ice Cream Man—_directed by Eli Roth—grossed $6 million off of a $5.5 million budget. This is a production of The Horror Section, which was one of the first “crowd investing” studios with 2,400 investors, which means that 2,400 investors probably lost money. They certainly aren’t getting as great of returns as if they had just invested their dollars in the stock market. Hopefully Stiletto (Tagline: “Someone’s Going to Make it Rain Blood!”) does better next month. WRONG: Another Data Goof Here’s another data error. When the first episode of House of the Dragon came out, HBO put out that it had 21.5 million viewers in the first three days, and I read that to mean in the US…but no, it was global. So my US-only datecdotes charts shouldn’t have included it. We never got US-only numbers for the first episode, but for the final episode, HBO put out that it had 11 million US viewers. (And that global dropped to 21 million viewers.) Here’s the updated chart (which I’ve since used in the Streaming Ratings Report): Still, this show is absolutely huge. RIGHT: Superhero Films Remain Very, Very Popular After Supergirl flopped, I read a few takes that “comic book movies are going the way of the Western”. Post-Spider-Man: Brand New Day, that take didn’t age well. To be fair, I have a very nuanced take on the superhero genre right now; it’s down right now, for a lot of reasons. But it’s not “dead”. Maybe _Spider-_Man is just a really popular character? I saw that take, and it’s a fair counter-argument. (But pundits arguing that superhero movies were dead should have mentioned this $1.5 billion counter-argument…) But is it just Spider-Man? The next Avengers film already has $50 million in pre-sales (and I was skeptical that that film would do well) and the Avengers: End Game re-release topped the box office two weekends ago (over three original films). And I wouldn’t bet against Batman or Superman. So maybe it’s just Spider-Man, Batman, Superman and the Avengers. Oh, and Deadpool, of course. And Black Panther. And Wolverine. And probably the X-Men. Plus a well-made Wonder Woman or the Hulk film could break out. But that’s it! It’s just those ten characters/teams. Oh, what’s that? Lanterns is also doing well on HBO? (See previous section…) To be fair, I’m actually pretty sympathetic to the argument that more popular characters—like Spider-Man and Batman—anchor more popular films. In fact, I made that exact argument three years ago when I first wrote about the “Marvel-cession”. In many ways, you can blame The Guardians of the Galaxy for fooling Marvel Studios (and the rest of us) into believing that any character could pop. It turns out, the list of iconic characters is probably smaller than most people think. But it’s probably too early to say that superhero films and comic book movies are dead unless “death” means a slight decline over a longtime. RIGHT: Who Killed Theaters? Old People I get frustrated whenever I see headlines or analysis about how young people are “returning” to theaters. As I’ve detailed(for years), young people have always powered the US box office, despite narratives about “kids these days” and their “phones”. Really, what’s changed post-2020/pandemic is that old people aren’t going to the movies nearly as much. This summer, I saw a movie (from an older director) in a theater near a retirement community, and multiple older people at the theater were talking about how this was their first time seeing a movie in years. I dislike personal anecdotes, so YouGov can fill in the data, best summarized by this headline: “Who killed movie theaters? Not the youths”. According to them, 64% of people aged 18-29 have seen a movie in the last year, but only 30% of 65-and-older. 20% of 18-29 have seen a movie in theaters in the last week and 42% in the last month. Here’s the polling data: Most concerning? Many Americans (17%) think theaters are a worse or much worse experience than watching films at home. Slight WRONG: Hadestown Opens Big A live theater capture of the Broadway musical, Hadestown, made $20 million at the US box office, which begs the question: was I wrong to be skeptical about musicals a few years ago? Yes and no. On the one hand, $20 million is a far cry from being “popular”, so yeah, the genre isn’t that popular overall and Hadestown is one of the more popular musicals from recent years (i.e. the “Taylor Swift Data Fallacy” in action). On the other, I doubt filming this cost all that much, and I don’t think that they spent much on marketing, so this is a good source of ancillary revenue. Smaller Updates WRONG: As I mentioned in a Streaming Ratings Report, I underestimated the budget for Enola Holmes 3. It probably cost more like $50 million, if not more. But... I’m not sure that it really matters? At sub-10 million hours, prices have to come down to make this work. WRONG: Netflix is giving Ink a 27-day in theaters! To quote the kids/YouTubers these days, let’s go! Now I might actually have a chance to see Danny Boyle’s latest in theaters. I’d complained about this in a “Coming Soon” section, but I was heartened to read that Netflix is giving multiple films longer theatrical windows this year. RIGHT: Netflix is sending 4-5 films per year to theaters. Netflix is slowly but surely sending more and more films to theaters, as I cautiously predicted earlier this year. For now, it’s just three big films and a number of awards contenders, but still, this is great news. And they’ll be releasing box office grosses! Just this week, Ted Sarandos confirmed that KPop Demon Hunters 2 will come to theaters (and my guess is it performs in the box office top ten at a minimum). WRONG: Angel has 3 million subscribers! How do I know this? Well, they told Deadline, who reported it. I marked this as “wrong”, since they’ve doubled their subscribers in one year but, you know, they don’t really have a hit film to speak of and they’re still losing money. WRONG: Furious was only renewed for one more season. I accidentally wrote “two more seasons” in my latest “Renewals, Cancellations, Un-Orders and Removals Update”. RIGHT: House of David is ending with its third season. In July, Prime Video renewed House of David for a third season, as I just wrote in my latest “Renewals and Cancellations” report. Well, now it’s ending after that third season. Why? As I’ve been writing, its viewership wasn’t great. I got feedback that this show didn’t cost very much, but it cost enough that its limited viewership didn’t save it. WRONG: Adults was a Hulu original! So I missed Adults when it first came out last year; I saw that it aired on FX and just assumed that it was a linear-first program. Turns out, it aired three episodes on FX, but binge-released the rest of its episodes the next day on Hulu. Huh. So I should have covered it last year! But I just wrote about it. 1 “When I was a kid in the 90s, if you wore a t-shirt to school that wasn’t too big and also wasn’t too small, but somehow didn’t quite fit, we’d say you were wearing an “extra-medium” shirt.” 2 As always, a huge exception is Disney, which barely makes anything original anymore.

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Oct 7 • 6:41 PM EDT • Entertainment • entertainment.substack.com
Epic used AI to find potential security flaws that could expose patient health records

Epic Systems revealed last month that it used an advanced artificial intelligence tool to find security weaknesses that could have allowed undetectable access to patient health data. Epic maintains health records for more than 325 million patients around the world.

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Oct 7 • 5:18 PM EDT • Health • wpr.org
Current NFL HC Emerges as Potential Lions DC

The Detroit Lions have not even fired their defensive coordinator, Kelvin Sheppard, and there are already ties and potential dots connecting to who the next coordinator is. While Tampa Bay Buccaneers head coach Todd Bowles is currently employed as well, his seat is as hot, if not hotter, than Sheppard.So, with Bowles needing a job […] The post Current NFL HC Emerges as Potential Lions DC appeared first on HEAVY.

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Oct 7 • 4:43 PM EDT • Sports • sports.yahoo.com
ChatGPT for Teens keeps teens talking, even during mental health crises

ChatGPT’s teen safeguards are meant to protect vulnerable users, but new testing found the chatbot continues encouraging engagement during crises and potentially encourages unhealthy relationships with the AI itself.

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Oct 7 • 2:15 PM EDT • Health • techcrunch.com
Lions Linked to Blockbuster Jalen Ramsey Trade

ESPN insider Jeremy Fowler floated Steelers star Jalen Ramsey as a potential Detroit Lions trade target as Brad Holmes searches for secondary help.

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Oct 7 • 12:57 PM EDT • Sports • sports.yahoo.com
Two icons, a glorious farewell and a potentially bitter ending

As Lionel Messi's international career ends in fond farewell, Cristiano Ronaldo's is at risk of petering out. BBC Sport takes a look at what could be the end of the international career's of two football greats.

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Oct 7 • 11:12 AM EDT • Sports • sports.yahoo.com
Improve your health habits with Wellness Wednesday

Coming up tomorrow at 9 a.m., MPR News host Angela Davis revisits Wellness Wednesday conversations about oral health, the potential benefits of fermented foods and how to prevent and detect colorectal cancers.

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Oct 7 • 10:00 AM EDT • Health • mprnews.org
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Senate passes healthcare cybersecurity bill after 190 million impacted by Change Healthcare breach

The Health Care Cybersecurity and Resiliency Act of 2026 was passed by unanimous consent last week, potentially expanding federal cyber requirements for healthcare organizations.

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Oct 7 • 9:54 AM EDT • Health • therecord.media
WHO questions Russia on reported second plague lab death

The World Health Organization is pressing Russia for more information about the unexplained death of a worker at a Siberian plague research institute — and a potential second incident. WHO Director…

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Oct 7 • 8:33 AM EDT • Health • thehill.com
AMO Pharma in Collaboration with Population Health Research Institute (PHRI) and Venca Research Inc. Announces FDA Advice on Potential Phase 3 Development Path for AMO-02 in Treatment of Arrhythmogenic Cardiomyopathy (ACM)

/PRNewswire/ -- AMO Pharma Limited ("AMO Pharma"), a privately held clinical-stage specialty biopharmaceutical company focusing on rare genetic disorders with...

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Oct 7 • 8:00 AM EDT • Health • prnewswire.com
The world's oyster reefs could add $12 trillion to planetary health each year—if they were better managed

A new study shows that the world's oyster reefs are a precious resource that's vastly underestimated and underutilized. The authors set out to calculate the reefs' potential gross ecosystem product (GEP), ...

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Oct 7 • 12:00 AM EDT • Health • phys.org
Stats and Observations From Phoenix Suns' Preseason Opening Loss

Jordan Ott’s high-volume offensive system flashed potential through aggressive rim pressure and hustle, but sloppy ball security and mounting fouls ultimately derailed the Suns' preseason opener.

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Oct 6 • 10:00 PM EDT • Sports • sports.yahoo.com
Trump admin struggles to get answers from Russia on potential plague death

The Trump administration is struggling to get clear answers about the death of a Russian laboratory worker at an institute dedicated to studying the plague, amid days of stonewalling from Russian officials about the mysterious circumstances surrounding the episode.

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Oct 6 • 5:53 PM EDT • Politics • cnn.com
Kings Coach Christie Believes Sharp Will Become a Fan Favorite

Emanuel Sharp impressed Doug Christie with relentless hustle and grit, signaling a potential breakout as Sacramento’s next shutdown perimeter threat.

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Oct 6 • 5:24 PM EDT • Sports • sports.yahoo.com
NCAA proposes summer competition for college basketball teams

The NCAA is proposing allowing summer competition between college basketball teams as a potential new revenue source.

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Oct 6 • 5:01 PM EDT • Sports • espn.com
'If Abdul can win in Michigan, anyone can win anywhere': Alexandria Ocasio-Cortez outlines stakes for progressives at NYC fundraiser

Ocasio-Cortez is traveling across the country as she considers her political future and potential bids for higher office in 2028.

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Oct 6 • 1:55 PM EDT • Politics • abcnews.com
Study: How GLP-1 meds used to treat sleep apnea may affect oral health

“We need to understand how these medications affect the mouth so we can identify potential problems early and make sure patients receive comprehensive care.”

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Oct 6 • 1:20 PM EDT • Health • jagwire.augusta.edu
UEFA monitoring Man City case before deciding on potential action

UEFA is monitoring Manchester City’s financial case and will wait for the Premier League disciplinary process to conclude before considering whether to take any action of its own.An independent comm...

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Oct 6 • 1:15 PM EDT • Sports • sports.yahoo.com
Lions Make Decision on Brian Branch, Cade Mays

Brian Branch and Cade Mays will be designated to return and begin practicing this week, giving the Detroit Lions two potential reinforcements.

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Oct 6 • 11:02 AM EDT • Sports • sports.yahoo.com
McKesson and CD&R to acquire Option Care Health for around $5.8B

The $5.8 billion transaction establishes a framework for McKesson to potentially acquire CD&R's stake.

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Oct 6 • 10:10 AM EDT • Health • axios.com
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Brazil: Lessons from a Disaster

By Antonio Martins (Outras Palavras) Defeats become deeper and more prolonged when we misunderstand what caused them, avoid correcting course, and embrace “solutions” that only compound our mistakes. Lula’s government and the Brazilian left suffered a disaster in Sunday’s election. Contrary to every poll, the president finished the first round 2.2 million votes behind Flávio Bolsonaro—and, more significantly, 3.4 million votes below his total four years ago, when the machinery of the state was working against him and in favor of his opponent. His vote share declined in 98 percent of Brazil’s municipalities. The PL, the main party of the far right, elected 121 deputies and 28 senators, becoming the largest caucus in both houses of Congress. The parties aligned with the Centrão—Brazil’s bloc of transactional center-right parties—were somewhat diminished, but will still hold roughly 250 seats in the Chamber of Deputies and 35 in the Senate. That will make it easier to assemble the majorities needed to amend the Constitution or impeach Supreme Federal Court justices. If elected, Flávio Bolsonaro could appoint four members of the Court, substantially altering its internal balance of power. What produced these results? How can the far right be prevented from consolidating them into a prolonged political hegemony? And what is the essential change of direction the left now needs? Explaining the Disaster Across the commercial media and the exuberant chaos of digital platforms, interpretations are multiplying. Some focus on specific episodes: Lula’s absence from the Globo debate, his very close relationship with Alexandre de Moraes, or his emphasis on issues supposedly remote from most people’s everyday concerns, such as rare earth minerals. Among the more systemic interpretations, three seem especially questionable. One argues that the principal defeat was not the left’s, since its congressional representation declined only slightly. The decisive movement captured at the ballot box, according to this view, was a shift within the right itself—from the more moderate and transactional forces of the Centrão toward the more ideological and radicalized forces of the PL and Novo. A second interpretation holds that the nature of electoral and political processes has changed. The material interests and aspirations of society, it argues, no longer play the central role they once did; they have given way to forms of subjective self-identification that the left has yet to understand. And a third concludes that, because of these two developments, we should expect a political winter: a prolonged period in which the far right and the broader right dominate Brazilian political life. There are important elements in all three interpretations. The problem lies in what they deny or leave out: Lula’s third government was a small-bore government. It offered the majorities that elected it neither a clearly better life nor reasons to believe again in politics and its power to transform society. These failures flowed from two fatal accommodations, which I will examine below. As a result, the government suffered a slow but steady erosion of support. And, as has happened in so many Western countries, it gave the far right the opportunity to present itself as anti-system and to benefit from popular frustration and distress. The interpretation that emphasizes the migration of votes from the center-right and traditional right toward the far right has been advanced, among others, by the courageous journalist Leonardo Sakamoto. In his UOL column on Monday, October 5, he highlights the miserable behavior of the traditional conservative parties. Over the past four years, they repeatedly joined forces with the “neo”-fascists, helping to “normalize” them—a criticism that could equally be directed at almost the entire corporate media. Believing they could use the far right as a stepping stone, they instead ended up partly devoured by it. This was especially true in the Senate, where the PL’s gain of 13 senators and Novo’s gain of two came at the expense of the PSD, which lost nine; the MDB, which lost two; the PSDB, which lost two; and the PP, which lost one. Sakamoto’s observation is accurate and necessary, but it leaves uncomfortable questions unanswered. Why did the erosion of the Centrão benefit the far right rather than, for example, producing growth for the left—as has happened so many times before, both in Brazil and elsewhere? The answer is not difficult. Throughout its four years in office, Lula’s third government was almost invariably associated with the Centrão. Here lies its first accommodation: accepting the limits imposed by conservative institutions; avoiding, as much as possible, any attempt to strain those limits through popular pressure; and believing only in the modest changes that could be squeezed through openings in Congress. The failure of the campaign to end the six-day workweek is emblematic. Lula could have electrified the presidential race by pairing it with a popular campaign for passage of the measure. Instead, he chose to place his hopes in the hands of Senate president Rodrigo Alcolumbre. He generated no mass mobilization, did not force his opponents onto an uncomfortable defensive, and won no victory. In September 2025, the government squandered the greatest of its many opportunities to shake up conservative power in Congress. Popular opposition to the so-called Shielding Amendment—which, if approved, would have restricted criminal proceedings against members of Congress—brought crowds into the streets, mobilized primarily by artists and social movements. This opened the possibility for a broader political education: a campaign that could begin exposing the limits and dysfunctions of Brazil’s political system while putting Bolsonaro’s movement on the defensive for its predictable support of political privilege. The amendment was defeated. But the executive branch then backed away from the fight. It remained associated with an institutional world widely seen as corrupt, elitist, and indifferent to ordinary people’s struggles. In doing so, it forfeited its credibility as a vehicle for the protest vote. On Sunday, it reaped the bitter fruits. Are We Doomed? Taking a different approach from Sakamoto, the philosopher Moysés Pinto Neto and other writers have drawn attention, in their first analyses of October 4, to the fragmentation of the public sphere produced by Big Tech platforms. Through their algorithms, these platforms present each person with a different view of social reality. As a consequence, it becomes much harder to identify common material problems and demands—for example, the fight for labor rights or for a properly funded public health system. Voters no longer embrace such demands, these authors argue, because they no longer see themselves as part of a collective. Instead, they tend to value the identities assigned to them by neoliberal subjectivity—the role of the entrepreneur, for example. On this interpretation, the left’s possible error lies in clinging to outdated illusions. Moysés’s warning is highly relevant and resonates with arguments such as Naomi Klein and Astra Taylor’s “Apocalyptic Fascism and the Billionaires’ Bet.” Unlike a century ago, the far right no longer promises a radiant future. It concentrates instead on resentment—especially that of young men. “They belong to a generation that fears it may never own a home, but compensates with the pleasure it gets from constantly provoking progressives online. Convinced their future has been stolen, they share memes romanticizing historical authoritarian regimes,” the authors write. But Moysés seems to confuse this danger with inevitability. He fails to see that the left’s answer cannot be adaptation. On the contrary, it must strengthen the possibility of politics as collective action. Nor does he recognize that precisely such a reversal is already becoming possible in some of the most promising mobilizations of the twenty-first century: the election, at the end of 2025, of the young Muslim Zohran Mamdani as mayor of New York, on a platform centered on the intensely material fight for an affordable city; the Left Party’s victory in Berlin two weeks ago, built around the demand to expropriate private real-estate corporations; and the very recent wave of demonstrations in Spain—including an occupation of Madrid’s Puerta del Sol—in which tens of thousands of young people mobilized by the Tenants’ Union have demanded limits on rents. By putting itself in the straitjacket of the “fiscal framework” in the first months of 2022, Lula’s third government adopted the second fatal accommodation of its term. Faced with conservative institutions and a country devastated by four years of Bolsonaro, increased public investment was the government’s remaining weapon for offering a more dignified life to the majority and forging an anti-conservative pact with them. The same state that disburses 1 trillion reais a year to enrich a small class of rentiers could instead spend money to extend the Family Health Strategy to every Brazilian, at a cost of 30 billion reais; provide full-day public schooling and childcare to all adolescents and children—and, especially, relief to their mothers; achieve universal sanitation while cleaning up polluted urban rivers; multiply metro systems; begin transforming the urban peripheries; and undertake many other urgently needed projects. In April 2023, an article in Outras Palavras warned that the fiscal framework could “shrink the Lula government and preserve the forces that condemn the country to inequality and regression.” A year later, another article showed that restraints on public spending were strangling policies vital to ordinary people and undermining the president’s popularity. In November 2024 came a reality check, in the form of the government’s humiliating defeat in the municipal elections. Even then, the fiscal lock was neither removed nor loosened. On the contrary: throughout the government’s four years, fiscal restraint remained central to its political narrative. The administration proudly proclaimed that it had “put the state’s accounts in order,” without grasping either how misleading that phrase was—given the payment of 1 trillion reais in interest—or how badly the message was hurting it politically. Lula finally woke up in September 2026. The increase in Bolsa Família benefits, after four years of being frozen; the announcement that anti-obesity drugs would be offered through Brazil’s public health system; and the ban on online betting showed that the state has the power to act decisively on behalf of the majority when those in government are willing to confront obstacles. The huge marches that closed the campaign in Fortaleza, Salvador, Rio de Janeiro, and São Paulo on the eve of October 4 showed how such initiatives can mobilize activists and the broader public. But it was too late—and too little to change the outcome of the first round. History has not ended The possibility of a turnaround in the three weeks leading up to November 25 cannot be ruled out. It will not be simple or easy. Lula must not only make up a deficit of 2.2 million votes; he must also offset the movement of voters who backed other right-wing candidates in the first round, most of whom are likely to move toward Flávio Bolsonaro. Pulling that off will require a broad, grassroots effort to win over voters, potentially reinforced by new initiatives from Lula. The coming hours and days will be decisive. If Bolsonaro’s movement also wins the presidency, the result will create a high-risk situation for Brazilian sovereignty and democracy. The enormous challenges posed by such an outcome would require the left to reexamine, in depth and with a genuine willingness to engage in self-criticism, its political projects—or its lack of them—and its practices. But would that mean we are condemned to the long winter of far-right hegemony that some analyses are beginning to forecast? It is far too early to say, suggests a recent text by Álvaro García Linera, the thinker who served as vice president of Bolivia under Evo Morales. His central hypothesis is that this political current will prove short-lived. At a moment when the entire world is once again talking about sovereignty and protecting national economies, the far right offers a stale, recolonizing neoliberalism. Its submission to the United States is as blatant and pathetic as Flávio and Eduardo Bolsonaro’s overtures to Donald Trump. Its project amounts to something like every man for himself: greater inequality, capitalism without limits, devastation, and supremacism. Will it work? In the United States, just two years into his second term, Trump himself is reaching record levels of unpopularity and may be on the verge of losing Republican control of both the House and Senate in November. Every new beginning is difficult. Whatever the outcome of the second round, the defeats of October 4 show how profoundly the Brazilian left will have to rethink and rebuild. But just as it would be foolish to underestimate the seriousness of its mistakes, it would be equally foolish to conclude that rebuilding a political project is no longer possible. History has not ended. The times are moving faster than ever. Originally published in Portuguese by Outras Palavras. English translation by Eric Blanc; I’ve added the subtitles. More We can’t stop the far right at home or abroad without a revitalized labor movement, which is yet another reason why you should become a sustaining supporter of the Emergency Workplace Organizing Committee (EWOC) — one of US labor’s pivotal bright spots. Relatedly, Jacobin published a short piece of mine reflecting on a decade of Bernie Sanders inspiring a whole new generation of young worker organizers.

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Oct 6 • 10:08 AM EDT • Politics • laborpolitics.com
ConocoPhillips Reviews Norway Business & UK Teesside Asset Divestment

COP is weighing a potential Norway and Teesside asset sale valued at about $7 billion, supporting portfolio optimization and capital flexibility.

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Oct 6 • 9:50 AM EDT • Business • finance.yahoo.com
"Still Looking" – Fabrizio Romano Reveals Man Utd's David Raum Stance

David Raum was mentioned as one of the potential left-back targets for Manchester United in the summer.

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Oct 6 • 9:16 AM EDT • Sports • sports.yahoo.com
StoneX maintains Buy rating on Sphere Entertainment, $125 price target

StoneX maintained their Buy rating on Sphere Entertainment's stock with a price target of $125.00.The price target implies an upside of 12.8% from the Oct 5 close of $110.80.Key takeaways from the analyst noteLong-Term Growth Potential: Despite recent challenges, Sphere Entertainment is expected to…

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Oct 6 • 8:36 AM EDT • Entertainment • tradingview.com
Thunder’s Reported Preseason Gamble Is Exactly Right

Prioritizing health and development, Mark Daigneault’s decision to bench established stars for hungry prospects offers a crucial evaluation of the roster’s next generation of potential contributors.

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Oct 6 • 7:00 AM EDT • Sports • sports.yahoo.com
BTIG maintains Buy rating on Sphere Entertainment, $160 price target

BTIG maintained their Buy rating on Sphere Entertainment's stock with a price target of $160.00.The price target implies an upside of 44.4% from the Oct 5 close of $110.80.Key takeaways from the analyst notePositive Long-Term Growth Potential: Sphere Entertainment is positioned uniquely in the grow…

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Oct 6 • 5:47 AM EDT • Entertainment • tradingview.com
Switching on brain cells: The Nobel-winning science of optogenetics

In optogenetics, scientists control neurons by stimulating them with light—potentially unlocking breakthroughs for conditions such as dementia, depression and blindness.

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Oct 6 • 2:20 AM EDT • Science • phys.org
Mental health stigma may deter treatment seeking in Japan

A UC Riverside-led study of mental health stigma in Japan has found a striking gap between the need for treatment and people's willingness to seek it, with high levels of social distancing toward people with mental illness serving as a potential barrier.

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Oct 6 • 1:43 AM EDT • Health • news-medical.net
Why So Many Social Science Claims Are False

One of the most urgent questions facing society today is the potential impact of AI on education and labor markets. So it’s no surprise that two scientists attempted to provide

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Oct 6 • 1:25 AM EDT • Science • themountaineer.com
Reddy Steward Faces Potential NFL Fine After Hit on Nico Collins
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Oct 5 • 8:17 PM EDT • Sports • sports.yahoo.com
Padres’ Potential Game 4 Starter Comes Back from Paternity List

Walker Buehler has spent the season being one of the San Diego Padres' most valuable starting pitchers. That might not be immediately apparent from the overlying statistics, but the metrics under the surface show a different picture. San Diego will be all hands on deck after dropping both games to the Milwaukee Brewers at American …

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Oct 5 • 8:04 PM EDT • Sports • sports.yahoo.com
Chiefs get major timeline for potential Tyreek Hill signing

The buzz for Tyreek Hill to Kansas City is growing after a report on Sunday night. On Monday, Hill's timeline to sign with a team was revealed and it is very close.

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Oct 5 • 6:20 PM EDT • Sports • sports.yahoo.com
Lions Get Potentially Huge Brian Branch News

Lions coach Dan Campbell is hopeful Brian Branch will return to practice this week, but that doesn't guarantee he'll play against Arizona.

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Oct 5 • 5:23 PM EDT • Sports • sports.yahoo.com
Ted Cruz Says JD Vance’s ‘Political Bomb-Throwing’ Shows He’s ‘Insecure’ Ahead of 2028 Election

While Vice President JD Vance might have been floated as a potential frontrunner for the Republican presidential nomination in the 2028 election, Senator Ted Cruz is doing his part to keep the party’s...

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Oct 5 • 4:10 PM EDT • Politics • yahoo.com
Bladen Community College to host “So You Want to Start a Small Business” class and preview Pitch It Bladen 2027

The Small Business Center at Bladen Community College invites aspiring entrepreneurs to attend “So You Want to Start a Small Business” on Tuesday, Oct. 13, 2026, from 6:00 p.m. to 8:00 p.m. in Building 14, Room 104. This class will help participants explore what it takes to become an entrepreneur and take the first steps toward turning a business idea into reality.Participants will explore the entrepreneurial mindset and consider whether they have the interests, characteristics, motivation and willingness to take on the challenges of business ownership. The class will encourage attendees to examine their personal goals, expectations, strengths and readiness to pursue entrepreneurship.Attendees will also gain insight into the realities of starting and operating a small business, including the commitment, planning, decision-making and perseverance required to build a successful venture. Whether participants are just beginning to consider business ownership or already have an idea they want to pursue, this class will provide a foundation for determining their next steps.In addition to the class instruction, attendees will receive advance information about the upcoming Pitch It Bladen 2027 Business Competition, including the application form and details about the program. Individuals who are ready to move forward may submit their applications early and have the opportunity to receive advance acceptance into the program.Pitch It Bladen helps aspiring and emerging entrepreneurs develop their business ideas through structured instruction in business planning, financial management, cash-flow projections, marketing and operations. Participants work toward completing a business plan and preparing a business pitch, with the opportunity to compete for cash prizes.Last year's Pitch It Bladen program demonstrated the value of investing in local entrepreneurs by helping participants strengthen their business knowledge, develop their business plans and prepare to present their ideas. The competition showcased the creativity and potential of Bladen County's small-business community and provided participants with practical tools to move their business goals forward.Building on that success, Pitch It Bladen 2027 will provide another opportunity for local entrepreneurs to gain knowledge, build confidence and take meaningful steps toward launching or growing a business.“The Small Business Center wants to help individuals make informed decisions about entrepreneurship before they take the leap into business ownership,” said Theresa Dennison, Small Business Center director, in a press release. “This class gives participants an opportunity to evaluate whether entrepreneurship is right for them while also introducing them to Pitch It Bladen 2027 and the resources available to help them succeed.”Registration: Visit www.ncsbc.net and search for the class by name, or contact the Small Business Center at 910-879-5572 for additional information.

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Oct 5 • 3:26 PM EDT • Business • bizfayetteville.com
Ana Navarro addresses Rosie O’Donnell’s potential return to “The View” (exclusive)

O’Donnell previously said that she’d return for season 30, while EW later confirmed a formal ask hadn’t gone out at the time.

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Oct 5 • 2:53 PM EDT • Entertainment • yahoo.com
Supreme Court weighs local governments' climate lawsuits against oil, gas firms

Key justices appeared wary about the potential sweep of litigation, but torn over the complex legal interplay of federal and state laws raised by the case

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Oct 5 • 2:42 PM EDT • Politics • spectrumlocalnews.com
Supreme Court weighs local governments' climate lawsuits against oil, gas firms

Key justices appeared wary about the potential sweep of litigation, but torn over the complex legal interplay of federal and state laws raised by the case

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Oct 5 • 2:42 PM EDT • Politics • spectrumlocalnews.com
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Rural and Urban Health Center Patients and Financing

This brief reports on rural and urban health center patients and financing in 2025 using national data from the Uniform Data System (UDS) and examines potential impacts of recent federal policy changes.

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Oct 5 • 1:47 PM EDT • Health • kff.org
Darling completes sale of sausage casings business to SARIA

Sale positions company for continued growth and value creation potential while optimizing portfolio and reducing debt.

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Oct 5 • 12:43 PM EDT • Business • feedstuffs.com
A ‘phoenix’ planet was born from the ashes of its dead star

Finding the potential planet hints that our sun’s death could lead to the creation of new worlds.

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Oct 5 • 11:00 AM EDT • Science • sciencenews.org
Supreme Court declines First Amendment case of students forced to remove ‘Let’s Go Brandon’ sweatshirts

The Supreme Court on Monday declined to take up a First Amendment appeal from two middle school students who were ordered to remove sweatshirts emblazoned with the words “Let’s Go Brandon,” steering clear of a case that could have clarified the power schools have to police potentially offense speech in the classroom.

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Oct 5 • 9:47 AM EDT • Politics • cnn.com
Are aliens real? Here’s what science can and can’t prove

Some scientists believe the sheer number of stars, planets and potentially habitable environments in space makes extraterrestrial life plausible. But plausibility is not proof. Despite decades of sear...

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Oct 5 • 7:17 AM EDT • Science • yahoo.com
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth

Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine

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Oct 5 • 6:44 AM EDT • Science • goldrushcam.com
UT San Antonio Health Science Center study finds elevated levels of toxicants in teeth of children with autism

Suggests children are ‘chronically and repeatedly exposed’ to dozens of potentially harmful chemicals Contact for media: Steven Lee, (210) 450-3823, lees22@uthscsa.edu Content provided by Claire Kowalick SAN ANTONIO, Oct. 5, 2026 – A pilot study by The University of Texas at San Antonio Health Science Center found elevated levels of toxicants in the primary teeth […]

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Oct 5 • 6:14 AM EDT • Science • news.uthscsa.edu
UT San Antonio Health Science Center study finds elevated levels of toxicants in teeth of children with autism

Suggests children are ‘chronically and repeatedly exposed’ to dozens of potentially harmful chemicals Contact for media: Steven Lee, (210) 450-3823, lees22@uthscsa.edu Content provided by Claire Kowalick SAN ANTONIO, Oct. 5, 2026 – A pilot study by The University of Texas at San Antonio Health Science Center found elevated levels of toxicants in the primary teeth […]

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Oct 5 • 6:14 AM EDT • Health • news.uthscsa.edu
Alex Scott Injury Raises Fresh Bournemouth Fears After England Break

Alex Scott's dream England breakthrough has been overshadowed by injury, with the Bournemouth midfielder potentially facing two months out. After a brilliant start to the season, his absence comes at the worst possible time, while his injury raises familiar frustrations around AFCB's rising stars.

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Oct 5 • 5:24 AM EDT • Sports • sports.yahoo.com
China develops plant to extract hydrogen, fresh water and uranium from the sea

Scientists improve on existing technology, plugging an overlooked energy leak to achieve a potentially profitable green solution.

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Oct 5 • 12:00 AM EDT • Science • scmp.com