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Long Reads for the Long Weekend
(Welcome to the Entertainment Strategy Guy, a newsletter on the entertainment industry and business strategy. I write a weekly Streaming Ratings Report and a bi-weekly strategy column, along with occasional deep dives into other topics, like today’s article. Please subscribe.) Happy Fourth of July weekend! As has been a tradition of mine going back to the beginning of the EntStrategyGuy website, I’m sharing my favorite long reads of the last year, like I did in 2019, 2020, 2021, 2024, and 2025. Let’s dive right in! Subscribe “Different Prices for the Same Ride: How Uber and Lyft Use AI to Get More Money Out of You“ by Derek Kravitz in Consumer Reports I don’t think surveillance pricing, like the kind described in this brilliant Consumer Reports article, is long for the world—it’s toxically unpopular—but we’ll see if either party takes on this issue. If I ran a political party focused on affordability, I would focus on a few pro-consumer and pro-market policies: Banning non-compete agreements. Ending surveillance pricing Eliminating junk fees (read more here...) Ensuring “right to repair” for consumer (and military!) products Capping excessive app store fees Stopping digital/algorithmic price-fixing tools. Preventing automatic subscription price increases. And more. If you want to fight inflation, there are a lot of great ways to do it quickly. Speaking of higher prices... “Secret Documents Show Pepsi and Walmart Colluded to Raise Food Prices Across the Economy“ by Matt Stoller in BIG Again, I think a political party should focus on lowering prices for consumers. And deals like this—Walmart making a deal/forcing Pepsi to offer the lowest prices at its stores and nowhere else—hypothetically lower prices at Walmart...but raise them everywhere else. “15 DUIs, still driving: California’s failure to take repeat drunk drivers off the road“ by Robert Lewis and Lauren Hepler in CalMatters CalMatters does terrific reporting in California, something the Golden State desperately needs more of, and this article is a great example of that. “PugLips: The next insanely popular thing you’ve never heard of…” by Simon Carless in Game Discover Co I thought that this parody article (and yes, it’s a parody, but I was definitely unsure at first) was hilarious and totally nailed how much tech/business journalism feels these days. Actually, three of my favorite articles this year were on hype in the video game industry, including Georg Zoller’s “The Video Game Industries Very Dark Night”—which I linked to recently and wrote a follow-up here—and Owen Mahoney’s “Derek Zoolander, Videogame Exec”. In particular, I like Mahoney’s focus on user experience as a guide to what trends will actually grab hold of customers. “The Matrix Lies“ by Evan Shapiro in Media War & Peace Evan Shapiro’s first person account of his experience with AI was hilarious. I think LLMs capabilities have significantly grown from last summer, and yet...my editor/researcher just had an abysmal experience using an LLM to do a quite basic task (which our LLM normally does each week) and the LLM made a mistake on every single data entry...along with seven different mistakes affecting twelve of the twenty or so entries, including mistakes that are explicitly spelled out in the prompt. That’s a brutal failure rate. Again, if you use AI/LLM for data collection, you need to take a lot of extra steps to verify and check the data. “Ghosts in the Balcony: A Cross-Country Trip to 58 Theaters Fighting to Survive“ by Matthew Frank in The Ankler I thought Matthew Frank’s pitch to head across America to visit theaters sounded insane aggressive at the time—at least it felt that way to someone a decade older than him; man, to be in your twenties again, am I right?—but I knew the result would be great. And it was, a terrific feature by a great young writer. Also, I loved Matthew’s recent article on who’s getting the precious few entry level jobs in Hollywood. (Hint: nepotism.) “Disney erased FiveThirtyEight“ and “Did Las Vegas get too greedy?” by Nate Silver in Silver Bulletin I love media history and analysis, and there’s no one better to get the history of FiveThirtyEight than from Nate Silver, who wrote about his personal experience in one of my favorite pieces from this year. I also loved Nate’s breakdown of what’s causing Vegas’ woes, but I’ll offer one criticism, summarized as “Might I suggest antitrust?” Many centrists/center-right/libertarian thinkers (Nate is self-described as the latter) often don’t consider consolidation or antitrust as factors in policy issues like housing, America’s military readiness, or, in this case, Las Vegas. Even if libertarians want to debunk antitrust/consolidation concerns, I’d love to read that debunking. In this case, Vegas is incredibly consolidated (though it also has been for a long time) and I’d have loved to read Nate at least contending with this factor, since he addresses almost every other potential factor for Vegas’ decline. “Why Microsoft’s Carbon Removal Pullback Is Such a Big Deal“ by Robinson Meyer in Heatmap News I’m a big supporter of carbon removal efforts, but this nascent industry faces a lot of headwinds, including this big move most recently. I think it’s clear that solar panels and batteries should be able to get the world to its carbon footprint goals, but effective carbon renewal remains necessary to prevent the worst impacts of global warming. “AI is killing the cheap smartphone“ by David Oks LLMs and AI will impact the world in ways we’re not ready for, and already, third world countries are seeing the prices of cheap cellphones skyrocket due to the cost of chips skyrocketing. This article by David Oks is a terrific breakdown. “100 Days of Madness: Netflix, Paramount, Warner and the Future of Hollywood“ by Wade Major at Hollywood Heretic Wade Major dove deep into Hollywood/streaming’s financials in this must read piece. Not that I agree with everything in this article (read my take on Warner Bros./Paramount here) but the analysis is top notch. I think many people discount how quality thinking, regardless of the argument/conclusion, will make you a better thinker. “Erased by the UFC: Frank Shamrock, The MMA GOAT of the 20th Century“ by Nate Wilcox in The MMA Draw Newsletter Growing up playing the UFC fighting game on the Dreamcast, Frank Shamrock was my favorite MMA fighter, and this history/tribute to him was great. Other Fun Reads “The Hardest Part Of History To Tell Is How It Felt“ by Craig Fehrman at Defector “Unmasking the Sea Star Killer“ by Craig Welch at bioGraphic “What Could Save the Industry? Fin-Syn“ by Richard Rushfield in The Ankler Alex Rollins Berg in Underexposed on movie bumpers, pillow shots, Disney trash cinema, cult films, and Casablanca. David H. Montgomery in YouGov’s The Surveyor on punctuation marks, condiments, dinosaurs, and comic strips and kids media. “How Medium finally pivoted its way to profitability“ and “Why the best journalists on YouTube are all former Vox employees“ by Simon Owens in Simon Owens’s Media Newsletter “It’s Not Just You, Netflix Shows Have Gotten Slightly Shorter: Here’s What the Data Says“ by Kasey Moore at What’s on Netflix “Numlock Awards: How Diane Warren became the biggest loser in Oscar history“ by Nathaniel Rakich and “Numlock Awards: The Oscar Bait era is over. The Oscar Chum era is here.” by Walt Hickey & Michael Domanico at Numlock Awards
Old muscle stem cells can act young again but there’s a catch
Scientists at UCLA discovered a surprising reason aging muscles heal more slowly. In older muscle stem cells, a protein called NDRG1 builds up and acts like a brake, slowing the cells’ ability to jump into repair mode after injury. But there’s a twist: that same protein helps the cells survive the stresses of aging, allowing them to stick around longer.
Athletics slugger Brent Rooker to have season-ending knee surgery
Athletics designated hitter Brent Rooker will undergo surgery to repair a cartilage tear in his left knee and miss the remainder of the season. “This is a big blow,” manager Mark Kotsay said Wednesday before the A's played the Los Angeles Dodgers. A two-time All-Star, Rooker hasn’t played since June 8.
The Science of NAD+: Why We Must Shift from Lifespan to Healthspan
Discover the science of NAD+ and how it impacts your healthspan. Watch Mona Rosene explain cellular repair and how to fight aging from within.
Crews called to overnight fire to auto repair business in Boonville
We’re told there was damage to the back corner of the business.
Crews called to overnight fire to auto repair business in Boonville
Crews called to overnight fire to auto repair business in Boonville
Crews called to overnight fire to auto repair business in Boonville
Crews called to overnight fire to auto repair business in Boonville
Crews called to overnight fire to auto repair business in Boonville
Crews called to overnight fire to auto repair business in Boonville
Businesses 'can't survive' Shirley roadworks, publican warns
Southern Water has been repairing a collapsed sewer in Shirley, Southampton since April.
These fat-filled brain cells may be making multiple sclerosis worse
Scientists have uncovered a surprising clue that may help explain why multiple sclerosis (MS) progresses rapidly in some people but not others. In brain tissue from patients with severe MS, researchers found large numbers of “foamy” immune cells packed with fat droplets after absorbing damaged myelin. These overloaded cells appear to switch from helping repair the brain to fueling ongoing damage and inflammation.
Scientists Discover Ultrasound May Stop Arthritis Before It Starts
A new study suggests low-intensity ultrasound can influence immune cell behavior in ways that may reduce chronic inflammation and encourage tissue repair after joint injury.
6 Ways Your Body Can Change After Starting a High-Protein Diet
Adding more protein to your diet can cause several changes in your body, such as better muscle repair and potential digestive issues.
Applications open for Hawaii County Kona low business recovery program
Eligible businesses can use the money for recovery needs, including equipment repair, temporary relocation costs and water damage.
Applications open for Hawaii County Kona low business recovery program
The reward from the county can be used for recovery needs, including equipment repair, temporary relocation costs and water damage.
ISS repair spacewalk highlights concerns about station health
NASA astronauts on the space station are preparing for a spacewalk to repair a robotic arm as safety advisers raise concerns about its long-term health.
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Chick-fil-A gets into the home repair and services business
The popular chicken chain has brought its hospitality prowess to a new industry in metro Atlanta — home services.
Tooting its own horn: Keller business with brass focus proves its mettle
Houghton Horns has been providing horn repair, service and supplies for 40 years.
AMC Entertainment Holdings (AMC) Is Down 16.5% After Dilutive Debt-Reduction Equity Raise - Has The Bull Case Changed?
Earlier today, AMC Entertainment Holdings announced a registered direct follow-on equity offering of 95,250,000 common shares at about US$2.10 each, aiming to raise roughly US$200.03 million primarily to redeem 6.125% Senior Subordinated Notes due 2027 and for general corporate purposes. This latest capital raise follows AMC’s roughly US$150 million at-the-market equity offering completed in early June, underlining how ongoing balance sheet repair is coming at the cost of further dilution...
Road-funding initiative in Colorado qualifies for November ballot
A measure that would dedicate all transportation-related revenue to Colorado’s roads and bridges has officially qualified for the November ballot after it cleared the state’s signature threshold, according to election officials. Backed by the coalition Restore Our Roads, Initiative No. 175 would require that all transportation-related revenue be used exclusively for building and repairing roads […]
What the Reflecting Pool debacle says about Trump and his presidency
The contrast from what Trump promised in April, when he announced his plan to repair and refurbish the pool, has been nightmarish.
DC Wrap: Vance claims progress in Iran talks; Reflecting Pool being repaired
A look at the day's biggest stories in national politics
Trump says repairs at Reflecting Pool will be 'taken care of' immediately
The firm that was awarded a $14.7 million contract to line the pool said it would make repairs “as part of the warranty”
Bones communicate with the rest of the body to support overall health – here’s the science behind your skeleton
Bones are living tissues that constantly rebuild, repair and help the body stay in balance.
Science-Backed Beauty Formulations Market Size and Growth Analysis Study 2026 to 2035
Global Science-Backed Beauty Formulations Market Size is predicted to grow at a 8.6% CAGR during the forecast period for 2026 to 2035. The skincare formulations segment is set to take a large share of the science-backed beauty market. This growth comes from more people focusing on skin health, anti-ageing, acne, hyperpigmentation, and barrier repair.
Scientists discover neurons must break their DNA to build the brain
As newborn neurons make their way through the developing brain, they must squeeze through incredibly tight spaces to reach their final destinations. Researchers discovered that this physical journey routinely causes some of the most severe forms of DNA damage—double-strand breaks—yet the young brain has evolved an impressive ability to repair the damage almost immediately.
This DNA repair gene went rogue and exposed a cancer weakness
Scientists have discovered that a gene normally considered a DNA-protecting "good guy" can become dangerous when cells make too much of it. The gene, EXO1, acts like molecular scissors that help repair DNA, but when overproduced it starts cutting DNA it shouldn't, creating damage linked to cancer.
Auto glass repair businesses suffer as Oakland break-ins decline
A decline in car break-ins across Oakland is being welcomed as a public safety win, but it is also contributing to a downturn for some local auto glass repair businesses.
Fewer car break-ins in Oakland means less business for repair shops
Oakland has seen a decrease in car break-ins over the past year, which is good news for car owners, but less so for some repair shops. Those businesses that specialize in replacing windows and windshields have seen a sharp decline in the once-reliable portion of their income.
Cold water changes your cells, and science says it only takes one week - Futura-Sciences
A daily dip in cold water might do more than jolt you awake. A study from the University of Ottawa suggests that a week of cold-water immersion can shift how cells protect and repair themselves, switching on a kind of internal cleanup crew. It is a striking finding, but also...
Businesses, commuters adjust for two-year Fort Bragg gate closure
The repairs to the All-American Freeway and the replacement of the Gruber Road Bridge are necessary investments, a Fort Bragg spokesperson said.
2-Alarm Fire Breaks Out At Restaurant In Milford, Fire Officials Say
The business will be temporarily closed until repairs and cleaning are complete.
With towing business, local man achieves dream
FAIRMONT – After several years honing his skills in and around the Fairmont area, Cameron Meyer has captured his dream by opening up his own business, CM Auto Repair and Towing. Meyer went to college for auto repair right out of high school, and has spent nearly 15 years working for multiple businesses in Fairmont. […]
Stanford scientists regrow lost cartilage and reverse arthritis in major breakthrough
A new treatment that blocks an aging-related protein restored lost cartilage in old mice and helped prevent arthritis after knee injuries. Human cartilage samples showed similar signs of regeneration, raising hopes for a future drug that could repair joints instead of replacing them.
Back to Business Program expands with increase to grant amounts
We designed the Back to Business Program to help small business owners recover from unexpected costs to repair and prevent vandalism and property damage. To meet the needs of businesses, we expanded the program to increase the grant amounts business owners can receive. Applications are open through December 2026, or until funds run out. Changes to […]
Construction causes power outage at PitCo Health and Human Services
Construction work hit a buried power line at 3 p.m. on Thursday that supplied grid and backup generator power to the Pitkin County Health and Human Services building, leading to necessary repairs that will last through the weekend and into next week.
Christopher Kim: Florida families and small businesses deserve the right to repair
Florida consumers deserve freedom to repair products they own.
Microrobots that could heal spinal injuries
Promising lab results for ‘microscopic repair crews, guided by magnets’
New Topeka vehicle repair business celebrates grand opening
There is a new vehicle collision repair business in Topeka ready to serve the capital city.
New gutter business offering installation, repairs now open in Tacoma
The Brothers That Just Do Gutters has expanded to the South Sound, offering a range of services for all things gutters.
HOA residents should not be contacting repair vendors
After reading the association’s letter, the violation letter is fairly standard. Many associations have such a noninterference policy as part of their rules and regulations.
Repairing DNA damage: Scientists discover a surprising new benefit of melatonin
A new study suggests melatonin supplements may help night shift workers boost their body's DNA repair processes, potentially offsetting some of the damage linked to working overnight. The findings are early but raise the possibility of a simple strategy to help reduce long-term health risks associated with night shift work.
Scientists are raising new questions about vitamin B12 and cancer
Vitamin B12 has long been seen as a health hero, helping the body make red blood cells, repair DNA, and keep nerves functioning properly. But scientists are discovering that the story may be more complicated than simply “more is better.” While too little B12 can damage DNA and raise cancer risk, some studies suggest that extremely high levels — especially from long-term high-dose supplements — may also be linked to certain cancers or poorer outcomes in cancer patients.
Photo Gallery: French surgeon who pioneered vocal cord repair visits Vanderbilt Health, observes seventh procedure
Marie, a physician from France who has spent over two decades honing the selective laryngeal reinnervation, presented at the second annual Robert H. Ossoff Lecture and was a guest in the operating room for Vanderbilt Health’s seventh such surgery.
Politics of potholes: why Bristol can’t fix its broken roads overnight
Marsh Street has been cited as Bristol’s worst for potholes. But it’s just one of many crumbling roads in Britain as councils face repairs backlogs and lack of funds
North Platte welcomes new boat sales and service business
Ott's Marine The Boat Life held its ribbon cutting ceremony in North Platte. The shop specializes in boat sales, service, maintenance and repairs for boating enthusiasts across the region.
MIT scientists discover amino acid that helps the gut heal itself
MIT scientists have identified cysteine — an amino acid found in foods like meat, dairy, beans, and nuts — as a potent trigger for intestinal repair. In mice, a cysteine-rich diet activated immune cells that released healing signals, helping stem cells rebuild damaged intestinal tissue after radiation exposure. Researchers say the discovery could eventually lead to new dietary therapies for cancer patients suffering from treatment-related gut damage.
Roanoke focus group wraps up Entertainment District talks; Berglund Center needs $30M+ in repairs
he Roanoke Entertainment District focus group met for the final time to discuss what comes next for the city’s performance and sports venue, the Berglund Center, as leaders weigh major repairs and long-term plans for the facility.
UT Health San Antonio researcher awarded $2.1M award to study cellular structures - UT Health San Antonio
Like a busy restaurant kitchen, our cells depend on well-organized working spaces to assemble the “recipes” that keep the body healthy. When these spaces are disrupted, important functions like gene regulation and DNA repair can go awry, promoting diseases such as cancer and neurodegeneration. UT San Antonio scientist David Libich, PhD, associate professor in […]
Scientists reverse Alzheimer’s in mice with breakthrough nanotechnology
A new nanotechnology treatment reversed Alzheimer’s symptoms in mice by restoring the brain’s natural cleanup system. The specially engineered nanoparticles helped clear toxic amyloid proteins from the brain and repair the blood-brain barrier, which normally protects and regulates the brain’s environment. In one striking experiment, elderly mice treated with the therapy later behaved like healthy younger mice.
Scientists discover why some cancers survive chemotherapy
Scientists have uncovered a surprising new trick used by one of cancer’s most notorious proteins. MYC, already infamous for fueling runaway tumor growth, also appears to help cancer cells survive by repairing their damaged DNA — including damage caused by chemotherapy and radiation. Researchers found that MYC can rush directly to broken DNA and recruit repair machinery, effectively helping tumors recover from treatments meant to destroy them.
Dallas weighs City Hall’s future as potential Mavericks sports, entertainment site
There were 418 submissions from residents, developers, architects, business leaders and others who responded to the city’s call for concepts favored repairing or restoring the Dallas City Hall.
What's next for Oakland County residents and businesses after water main break
Officials say the repair itself is expected to cost between $3 and $5 million.
NASA Knows: The Ozone Hole
This is the story of the hole in Earth's protective ozone layer: what it is, how it formed, and the decades-long effort to repair it.
Oakland County businesses working to move forward amid water main break repairs
Being a small business owner comes with its own challenges, and when you add a pipe burst to the mix, Lake Orion Coffee Shop owner Charlie McClenaghan says you never really know how to prepare.
Oakland County business moving forward amid water main break repairs
‘Fake, Fake, Fake’: Regulators sue company behind fake home repair businesses exposed by KARE 11 investigation
Water main break forces Lake Orion businesses to close on Mother's Day; most remain shut down
Daily 5 report for May 8: Why this dealer sold his collision repair business
John Masano sold his collision repair business to Driving Force Collision in 2024 to focus on dealership sales and service operations instead.
The National Academy of Sciences Elects Two Berkeley Lab Researchers
Two Lawrence Berkeley National Laboratory (Berkeley Lab) scientists have been elected to the National Academy of Sciences (NAS) in recognition of their distinguished and continuing achievements in original research. They are part of a cohort of 120 new members and 25 international members. The National Academy of Sciences is a private, nonprofit institution that was established under a congressional charter signed by President Abraham Lincoln in 1863. It recognizes achievement in science by election to membership, and — alongside the National Academy of Engineering and the National Academy of Medicine — provides science, engineering, and health policy advice to the federal government and other organizations. The 2026 electees bring the total number of active members to 2,705 with 557 international members. Gary Karpen is a biologist senior faculty scientist in Berkeley Lab’s Biological Systems and Engineering Division and a Professor of Cell and Developmental Physiology in the Department of Molecular and Cell Biology at UC Berkeley. Karpen studies how the structure, organization, and maintenance of genetic material impact inheritance and cell function. His lab focuses on chromatin — a packaged form of DNA strands wrapped around proteins that comprises our chromosomes — with a particular emphasis on centromeres, rarely expressed sequences called heterochromatin, DNA repair, and regulatory RNAs. His research reveals insights into fundamental aspects of nuclear organization and genome regulation that are shared across the tree of life, broadening our understanding of cancer and other diseases, birth defects, and aging. Kam-Biu Luk is a Professor Emeritus of physics at UC Berkeley and a retired senior faculty scientist in Berkeley Lab’s Physics Division. He is an experimental particle physicist whose research has focused on neutrinos: nearly massless, electrically neutral elementary particles that can pass through matter virtually undetected. Neutrinos are created during radioactive decay processes, including the fusion process occurring in stars and the fission process that powers nuclear reactors. Luk initiated and co-led the Daya Bay Reactor Neutrino Experiment, a project based in China with more than 200 international collaborators. In 2012, the Daya Bay experiment discovered a new form of a phenomenon called “neutrino oscillation” in which neutrinos change from one type to another. For this discovery, Luk and his collaborator Yifan Wang received the 2014 American Physical Society Division of Particles and Fields W.K.H. Panofsky Prize for outstanding work in experimental particle physics, and he was also the co-recipient of the 2016 Breakthrough Prize. Luk is currently participating in the Deep Underground Neutrino Experiment (DUNE) hosted by Fermi National Accelerator Laboratory, which will investigate any potential difference in behavior between neutrinos and antineutrinos that may shed light on the evolution of the universe, especially why antimatter is absent in the present universe. ### Lawrence Berkeley National Laboratory (Berkeley Lab) is committed to groundbreaking research focused on discovery science and solutions for abundant and reliable energy supplies. The lab’s expertise spans materials, chemistry, physics, biology, earth and environmental science, mathematics, and computing. Researchers from around the world rely on the lab’s world-class scientific facilities for their own pioneering research. Founded in 1931 on the belief that the biggest problems are best addressed by teams, Berkeley Lab and its scientists have been recognized with 17 Nobel Prizes. Berkeley Lab is a multiprogram national laboratory managed by the University of California for the U.S. Department of Energy’s Office of Science. DOE’s Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit energy.gov/science.
Rubio’s Rome mission balances diplomacy and Republican politics
As global affairs expert Ian Lesser argues, Marco Rubio’s visit to Rome is unlikely to fully repair recent tensions between Washington, Italy and the Vatican, but it could still help ease the political climate. According to Lesser, Rubio embodies a more diplomatic and moderate Republican voice, yet remains constrained by the broader posture of the [...]
'iPhone Ultra' Could Be Industry's Most Repairable Foldable
The leaker "Instant Digital" today revisited their February design report on the foldable iPhone, claiming the device's internal design will make it the easiest-to-disassemble and easiest-to-repair foldable phone in the industry. In a new post on Weibo, Instant Digital said the device's "incredibly rigorous underlying engineering logic" has "truly paid off," and predicted that teardown videos will vindicate the earlier claims once the device ships.
After attack, Multnomah Athletic Club will stay closed for at least a week
Staff of the membership-based social and sports club say the MAC will reopen, but they need time to make repairs.
My Biz: Marion auto repair business finds a European niche
The staff at EuroCare auto repair shop in Marion, Iowa, includes 6 factory-certified technicians who stay current with the needs of imported cars that tend to be more expensive but have expired warranties.
Lower Burrell nets air conditioning and heating business at former Hillcrest Volkswagen
Mark Williamson is in the business of heating and cooling, but he says his company’s ethos is a bit more than that. MW Mechanical Services, which Williamson founded in New Kensington in 2022, installs and repairs residential and commercial air conditioning and heating systems across Soutwestern Pennsylvania. It also services
Pentagon’s $25 billion cost estimate for Iran war is low and does not include cost of rebuilding US bases, sources say
The $25 billion estimate that a top Pentagon official gave to lawmakers on Wednesday for the total cost to date of the Iran war is a lowball figure that does not include the cost of repairing extensive damage suffered by US bases in the region, three people familiar with the matter told CNN.
Proposal exempting some IT equipment from Colorado’s ‘right to repair’ law fails
A bill proposing an exemption to Colorado’s “right to repair” laws for “critical infrastructure” failed to pass its first committee in the House after clearing the Senate. Senate Bill 090 would have exempted information technology equipment considered “critical infrastructure” — defined by the federal government as physical and information systems and assets essential to the […]
Tensor G6 reportedly bringing latest ARM CPU cores but outdated GPU to Pixel 11
An early, limited leak around Google’s upcoming Pixel 11 series offers some limited details around the Tensor G6 chipset inside,...
Framework Laptop 16 Gets NVIDIA RTX 5070 12 GB Upgrade Module for Eyewatering Price
Framework, known for its repairable and upgradeable gaming and productivity laptops, has officially released a Laptop 16 graphics upgrade module with the new NVIDIA GeForce RTX 5070 12 GB. Framework's original Laptop 16 graphics expansion module, which upgrades the original $350 AMD Radeon RX 7700S,...
King Charles steps into political storm during high-stakes US trip
Royal broadcaster Neil Sean joins ‘Varney & Co.’ to break down King Charles’ Washington visit, efforts to repair U.S.-U.K. ties, and the latest royal drama involving Prince Harry and Meghan Markle.
BUSINESS PERSPECTIVES: BerkShares Business of the Month is Hart GB
"I made the sweater I’m wearing right now, and I like to be making things and repairing things, so whether that is craft or art doesn’t matter so much to me," said Jamie Goldenberg, owner of Hart GB. What does matter is that I’m using my mind and my hands to figure out the world around me by interacting with it."
Fish oil may be hurting your brain, new study finds
Fish oil has long been praised as brain-boosting, but new research suggests the story may be more complicated. Scientists found that in people with repeated mild head injuries, a key omega-3 fatty acid in fish oil—EPA—may actually interfere with the brain’s ability to repair itself. Instead of helping recovery, it appears to weaken blood vessel stability, disrupt healing signals, and even contribute to harmful protein buildup linked to cognitive decline.
Jermod McCoy says doctors that did surgery told him knee is healthy for NFL
Jermod McCoy said doctors told him his surgically-repaired knee is healthy and ready for the NFL, but he'll let the Raiders decide what's next.
Minnesota’s largest indoor ice rink is in desperate need of repair
The NSC Super Rink is where the U.S. women’s Olympic roster, Bethel University and a handful of local high school and youth hockey teams skate.
2,200-year-old Roman shipwreck unlocks mysteries of how ships were built and repaired
And it’s all thanks to little bits of pollen stored in the wood beams.
Framework’s New Ultra-Repairable 'Pro' Laptop Lets You Ditch Windows Entirely
The Framework Laptop 13 Pro comes with better battery life, a better chip, and—finally—a touchscreen.
Mobility equipment repairs, health services available at Caldwell Health and Resource Fair
Seniors and other Idaho residents are encouraged to attend a health resources and social services fair on Wednesday in Caldwell.
Rare Cooler Master GeForce RTX 5080 shows up at repair shop, turns out it wasn't even broken
Limited Cooler Master RTX 5080 sent for repair after PSU swap What do you do when you install new hardware and see a spark inside your PC? The last thing
Better Business Bureau warns of storm repair scams ahead of severe weather
The Better Business Bureau warns of storm repair scams following severe weather. Learn red flags to watch for and how to protect yourself from contractor fraud.
iPhone 17 Pro Max Units With Dents And Scuffs Are Being Restored To Near-Pristine Levels, Similar To Cars Getting Repaired
Some owners cannot stand the sight of their shiny new iPhone 17 Pro Max getting bumps or scratches, causing them to seek those who can restore them
Resilient Entrepreneur Program Elevates Local Businesses
Johanna Robinson joined the Resilient Entrepreneur Program (REP) at Cal State San Marcos with a three-ring binder filled with sketches of two kittens inspired by her twin daughters. She wasn't sure if her project would become a children's book, an animated series or something else entirely."I was thrilled to be accepted," Robinson says. “As a...
Webster Groves business waits week for answers after water main break
A heating and air conditioning business is waiting for cleanup and repairs a week after a water main break flooded its basement
Knoxville couple claim scammer used their business name to pose as repairman
KNOXVILLE, Tenn. (WATE) — A Knoxville couple who operate an appliance repair business says their company name is being used by a scammer. The couple says the scammer has been operating for more tha…
‘Pothole Politics’ Meets a Hell’s Kitchen Crater at W42nd & 9th Avenue
Three weeks of sewer repairs snarl traffic at W42nd and 9th, exposing underground infrastructure clashes and testing Hell’s Kitchen patience.
Asking Eric: My brother and I are estranged due to political disagreements
In today's Asking Eric column, R. Eric Thomas responds to someone who isn't sure they can repair their broken relationship with their brother.
Water main break causes headaches for Gwinnett County business owners
The water main break took over 12 hours to repair.
The Kennedy Center wants to show that the building really needs a renovation
The Kennedy Center's new president, Matt Floca, is leading tours to show the building's need for major repairs | 830 WCCO
IMF director says shock from US-Iran War is 'baked' into the economy
War has ravaged the Middle East for 43 days, but the damage could take years to repair amid tension at the Strait of Hormuz and damaged oil hubs.
Mid-Missouri event offers free health services, brake light repairs and meals
Tallgrass Collective hosted a free clinic offering health services, vehicle brake light repairs, food and clothes Saturday from 11 a.m. to 2 p.m.
Framework CEO warns AI boom may lead to a scenario where "personal computing as we know it is dead”
Framework CEO Nirav Patel warns that the AI boom and a “winner-takes-all” scramble for chips and storage could drive up component costs and push consumers toward cloud-leased, closed devices, effectively ending personal computing as traditionally understood. While acknowledging progress in repairability across the industry, he positions Framework’s upcoming Next Gen Event as part of a renewed pledge to defend user ownership through upgradable, repairable hardware and local control over data and computation.
MDOT plans $1.5M repair project on I-94 Business Loop in Marysville
Drivers in Marysville can expect lane shifts and closures as MDOT begins a $1.5M repair project on the I-94 Business Loop starting April 20.
Google Pixel bests iPhone and Samsung in repairability name-and-shame report
A new report calls out the top smartphone makers in the US for their poor device repairability scores, but Google...
Apple gets bottom ranking for repairability of iPhones and MacBooks
Repairability ratings based on official government criteria in Europe have found that Apple gets the worst ratings for the repairability...
Apple has the lowest grades in laptop, phone repairability analysis
The MacBook Neo is a step in the right direction, though.
New Research Brings Joint Repair Closer for Millions With Osteoarthritis
DURHAM, N.C. — Osteoarthritis affects more than 32 million Americans, making it one of the leading causes of chronic pain, disability, and loss of mobility in the United States.For many people, treatment options are limited to managing pain with medications or repeated injections, and in severe cases, replacing the joint entirely through surgery.
Inside the Rays’ new era: A Q&A with Ken Babby on Opening Day, fans and what’s next for a new ballpark
'Fans can expect our organization to be determined, accountable and accessible, as they should.'
Google Pixel 10a disassembly nets it a very good repairability score
You can see the whole process in this video. Google launched the Pixel 10a in February and released it in early March, and today a video showing its...
Tarrytown spa undergoing repairs after SUV crashed into business
Repairs are underway at a Tarrytown spa after an SUV crashed into the business. The business hopes to reopen in early May.
Local garage door repair business, customers targeted by nationwide scam
Fallout from a nationwide trend of garage door repair scams showed up at the doorstep of Ray and Brad Larson in the form of angry customers they never heard of.