SCROLL NEWS / DISCOVERY
Search headlines
Find the stories shaping the conversation.
Results for " bt " 3,684 found 🔀 AI-powered Shuffle
Subtle health changes may signal progressive supranuclear palsy years in advance
Drawing from UK Biobank data, Mass General Brigham researchers have uncovered specific health factors linked to higher or lower risk of developing progressive supranuclear palsy (PSP), a rare but devastating ...
Investors Question Whether Quick Peace in Iran Is Possible
Global markets are under pressure again amid doubts that the fighting in the Middle East can end anytime soon.
‘Corpus Christi’ returns to the Bartell, years after protests
StageQ, Madison’s LGBTQ community theater, stages Terrence McNally’s controversial retelling of Jesus’ life and crucifixion through Easter weekend.
Health inspectors found thawed seafood, food stored in buckets leading to temporary closure of Mama Tina’s Gumbo
Houston health inspectors investigating a customer illness complaint after eating Mama Tina’s Gumbo at the Houston Livestock Show & Rodeo found thawed seafood labeled “keep frozen” and learned the gumbo had been moved to a freezer at an unlicensed off-site location without temperature logs before being served, according to Houston Health Department records obtained by KPRC 2 News.
Major PlayStation Store Purge - Sony Removes Over 1000 Games
Sony continues to clean up the virtual storefronts.
'BTS: The Return' review: The world's biggest boy band, without a clear direction
The documentary is an intimate, surprisingly revelatory look at BTS in transition — and the complicated process of figuring out who they are now.
Doubts from key Republicans on surgeon general test MAHA’s political power
Casey Means faces pushback from some Republicans over her refusal to forcefully recommend vaccines.
Why the BTS Comeback Concert Was a ‘Disaster’ for Some Businesses
The turnout for the K-pop titans’ show was much lower than projected by officials, hitting the bottom line of some restaurants. Shares in the group’s management company also fell.
Berrien County Health Department will hold free hearing, vision screenings for kids
The Berrien County Health Department will offer free hearing and vision screenings for kids throughout spring break.Clinics will be held March 30 at the departm
What events are happening in the South Bend area from March 23 to 29?
A variety of events will keep you busy this week. Attend a screening event, catch a concert, attend a lecture or play.
Devin Booker gets 100% on Suns’ playoff seeding chase
Devin Booker knows where the Suns sit amid their previous five-game skid and how it impacts the playoff seeding chase.
Everything you need to know about 'BTS: The Return,' the new Netflix documentary
On Friday, Netflix will release a documentary about the biggest band in K-pop, BTS. It is titled “BTS: The Return.” It is from director Bao Nguyen. He is known for his work on “The Stringer”...
Everything you need to know about 'BTS: The Return,' the new Netflix documentary
On Friday, Netflix will release a documentary about the biggest band in K-pop, BTS. It is titled “BTS: The Return.” It is from director Bao Nguyen. He is known for his work on “The Stringer”...
Everything you need to know about 'BTS: The Return,' the new Netflix documentary
On Friday, Netflix will release a documentary about the biggest band in K-pop, BTS.
Scholar Athlete of the Week: Andra Stokes, Stevens High School
KSAT 12 Sports and CHRISTUS Children’s shine a spotlight on a local senior student athlete
One dead after shooting at Last Call Sports Bar in Jackson
One person is dead after a shooting at Last Call Sports Bar early Sunday morning.
A DNA test ruled him out. He was convicted of murder anyway.
Forensics has its share of high-profile problems. There’s phony “junk science,” like bogus bite-mark and blood spatter analyses that have sent innocent people to jail. And there’s the steady drumbeat of lab scandals, where analysts make up results. But there’s a subtler and more pervasive problem at work in many cases: lab analysts and lawyers who take perfectly legitimate science and twist it. Globe Opinion is exploring these distortions with a series we’re calling “Twisted Science.” And there may be no better place to start than with the case of Terrel Barros.
Nevada Wins Temporary Ban on Sports Betting on Kalshi
The prediction-market platform must obtain state gambling licenses and prohibit users under 21 to offer such contracts, a state court said.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Scientists Uncover Hidden “Second Layer” in Human DNA
A newly identified cellular system monitors subtle variations in genetic coding, hinting at a hidden level of control over how genes are expressed.
Marc Abrahams, founder of the satirical Ig Nobel Prizes: ‘Scientists in the US are very angry. People are waking up’
The awards are moving to Switzerland, because their founder believes he can no longer guarantee the laureates’ safety in the United States
Scientists Propose a Radical New Way To Detect Gravitational Waves Using Atomic Light
A new theoretical study suggests that gravitational waves may leave subtle signatures not in giant detectors, but in the light emitted by atoms.
Austin soul food staple Hoover’s Cooking to close after nearly 30 years
While the Manor Road soul food spot is ending its sit down dining service, it will still book private events through the summer.
Top business aviation banker talks debt, profits, JetGate, EBITDAR
Jefferies' Nick Fazioli on why Wall Street loves private jets, non-GAAP financial metrics and why past results don't preclude more investment
Robert Mueller, former FBI director and special counsel in Trump-Russia probe, dies
Robert Mueller, the former FBI director who led the historic probe into alleged collusion between Donald Trump’s 2016 campaign and the Russian government, has died, according to a family statement obtained by The New York Times and the Associated Press. He was 81.
Robert S. Mueller III, 81, Dies; Rebuilt F.B.I. and Led Trump Inquiry
After he concluded that Russia had interfered in the 2016 election, he became a target of the president’s anger.
Hubert Davis' future at North Carolina in serious doubt as pressure mounts after historic collapse
Sources tell CBS Sports that Hubert Davis' future at North Carolina is in serious doubt after a historic NCAA Tournament collapse, with boosters losing faith and questioning their willingness to fund the program.
BTS fans take over central Seoul for K-pop kings' comeback
South Korean megastars BTS reunite Saturday for their first show in nearly four years, with an expected 260,000 fans taking over central Seoul for a K-pop extravaganza livestreamed to millions more wo...
‘Very foolish mistake’: Trump lashes out at NATO allies over their refusal to help
Building Brighter Tomorrows: Advancing Community Health in 2026 and Beyond
The Institute for the Advancement of Community Health, in partnership with the Institute for Child Success, is hosting the 2026 Building Brighter Tomorrows Conference on Thursday, April 16 at Furman […]
Chicago's teetering debt is stark warning left-wing mayor is fueling 'pay later' doom cycle: expert
Expert Austin Berg warns Chicago's "pay later" debt culture under Mayor Brandon Johnson is alarming markets with a $1 billion budget gap and risky bond deals.
Jefferson Health hit with $108 million verdict in Einstein birth injury case
The verdict is the biggest medical malpractice verdict in the city since a record-setting $183 million award against Penn Medicine three yeas ago in another birth-injury case.
Overcoming Self-Doubt When Launching Your Own Business
Building a company will always test your confidence. Some days will stretch it; others will rattle it to the core. Self-doubt in those moments is not a sign you’re not cut out to lead. It’s what happens when you’re creating something new, the stakes are real, and you care deeply about the outcome. The founders who lead well over the long run aren’t the ones who never doubt themselves. They are the ones who have learned to work with it.
Researcher: Addressing runaway college sports spending in Virginia
This whole college sports enterprise is business development that is being financed by student subsidies, and frequently ever higher student loan debt. As a society, do we do this for any other fo…
NYC health budget plan: More support for children, less for fighting disease
The $2.51 billion spending plan includes increases for early childhood initiatives and a new public health lab - but less funding to fight communicable diseases, sexually transmitted infections, and tuberculosis.
Warriors’ nightmare seeding, matchup scenarios for 2026 NBA Playoffs
The Warriors are in the middle of a nightmare season, and it would be painful for fans if they witness their season end in a nightmare too.
How YouTuber Caleb Hammer built a big business on debt call-outs
Caleb Hammer, who built a large audience by blending personal drama with money advice, has parlayed that into a lucrative subscription business.
Forum on harnessing Artificial Intelligence for health equity
Register to this forumOver the past decade, artificial intelligence (AI) has significantly evolved in complexity, performance, and utility. Its integration across a wide range of industrial sectors has accelerated, with healthcare emerging as one of the most transformative sectors. In this sector, AI has enabled high-impact applications – from enhancing the speed and accuracy of disease diagnosis and supporting clinical decision-making, to strengthening public health initiatives such as disease surveillance and workforce optimization. Moreover, AI holds immense potential to empower individuals, enabling them to take greater control of their personal health and well-being. Yet the central question remains: Who benefits, who is at risk, and do these innovations close or widen health inequities? While the potential of AI-enabled applications is substantial, many countries have approached their adoption with caution. This hesitancy stems from concerns about risks and benefits, including model bias, data breaches, privacy violations, and the erosion of professional skills due to over-reliance on AI. Additional barriers include inadequate data infrastructure and a lack of robust evidence on the most effective forms and interfaces of AI to enhance service delivery and system performance. Moreover, the rapid rise of Generative AI has introduced a heightened urgency for the development of comprehensive governance and ethical frameworks. The Asian Development Bank (ADB) Health Practice Team and Digital Sector, in collaboration with the World Health Organization (WHO) Regional Office for the Western Pacific, are convening the Forum on Harnessing AI for Health Equity on 25–26 March at ADB Headquarters. Senior health officials from 16 developing member countries (DMCs), alongside leading researchers, innovators, and policymakers from across Asia and the Pacific, will engage in discussions on how AI can be governed, financed, and scaled to deliver healthier lives for all. The forum is funded through the High-Level Technology Fund with support from the Government of Japan. Objectives The two-day forum aims to:Identify high-impact, evidence-based health AI use cases suitable for resource-constrained settings and map out a pipeline for potential supportIntroduce and validate the WHO's policy guidance on minimum necessary ecosystem for countries and institutions to self-assess readiness for AI adoptionObtain initial commitment from participating stakeholders to join a pilot regional initiative focused on data/model sharing for a priority health challengeEndorse a prioritized set of actionable policy recommendations focusing on governance, regulation, and sustainable financing necessary to scale high-impact health AI use cases in resource-constrained settings Target participants The forum will convene participants from 16 ADB DMCs including Bangladesh, Bhutan, Cambodia, Cook Islands, Fiji, Indonesia, Lao People's Democratic Republic, Mongolia, Nepal, Palau, Papua New Guinea, Philippines, Sri Lanka, Thailand, Uzbekistan, and Viet Nam. In addition, health system leaders and practitioners, private sector technologists, academic experts, representatives from civil society organizations, development partners, and philanthropic institutions engaged in AI for Health from Australia, the People’s Republic of China, Japan, Malaysia, New Zealand, Singapore, and the Republic of Korea will also be invited. SessionsDay 1 (25 March)Session 1: AI Use Cases for the Care Continuum: Improving Access and QualitySession 2: Adopting a risk-based approach for AI use case prioritizationSession 3: Establishing the Minimum Ecosystem for Implementation Risk ManagementSession 4: Future-Ready Health Workforce: Building Competency for Human-AI CollaborationDay 2 (26 March)Session 5: The Political Economy of AI in Health: Understanding Stakeholder Interests and their Impact on EquitySession 6: AI and Health Financing: Supporting Fair Coverage and ProtectionSession 7: AI Regulation and Oversight: Pathways for Different RealitiesSession 8: The Way Forward – Building Alliances and Regional Partnership How to registerThe forum will be held in a hybrid format. In-person attendance is by invitation only, while livestreaming of the forum will be available to the public. To register, please complete this form on or before 24 March 2026.Event organizers / partnersAsian Development Bank (ADB)WHO Regional Office for the Western Pacific High-Level Technology Fund (HLTF)ContactAkihito WatabeHealth Specialist, SD3-HSDawatabe@adb.org Jae Kyoun KimHealth Specialist, SD3-HSDjkkim@adb.org
Stalled train blocks Brazos County business, homes for nearly a week
Union Pacific confirms mechanical issues caused the delay; train expected to move soon
Finding Easter eggs in entertainment boosts enjoyment and fan behavior, study finds
If you've watched popular movies or television shows in the last decade, there's a good chance you've found an Easter egg or two: not an actual brightly colored egg but a subtle reference to another movie ...
Koreatown rideshare driver arrested for allegedly using $2M in COVID business loans for crypto investment
A rideshare driver from Los Angeles’ Koreatown neighborhood has been arrested for allegedly using more than $2 million in fraudulently obtained COVID-19 pandemic business loans to buy cryptocurrenc…
General Mills offloads Brazil business as sales dip
The Golden Valley-based food company posted profit lower than Wall Street’s expectations, and this latest divestiture will help it focus on pet food and other growing segments.
Personal trainer dies from fatal injuries sustained inside North Carolina business
The 71-year-old was a personal trainer in Whiteville.
Is Kohl's going out of business? What to know about Michigan closures
Kohl's recently closed two Michigan stores. Here's what to know.
BrightSpring Health (BTSG) Climbs 7.8% on Double-Digit Growth Outlook
BrightSpring Health Services Inc. (NASDAQ:BTSG) is one of the 10 Stocks That Made Millionaires Today. BrightSpring rallied for a second day on Tuesday, jumping 7.81 percent to finish at $42.10 apiece, as investors welcomed the company’s reaffirmed growth outlook for this year. In a shareholders’ meeting on the same day, BrightSpring Health Services Inc. (NASDAQ:BTSG) […]
Stada Hunts for Major Consumer Health Deal After Record Profit
German pharmaceutical firm Stada said it’s ready to make a major consumer health acquisition as it books record profit and transitions to new ownership.
Cash Crunch Drives Nigerian Power Producers Out of Business
A number of heavily indebted Nigerian power producers have ceased operating because their customers aren’t settling their bills and they can’t afford to run their equipment or pay for gas supplies.
Oscar ratings fall 9% in Conan O’Brien’s second year hosting
The 98th Oscars hosted by Conan O'Brien saw a dip in ratings after several years of gains. The Walt Disney Co. on Tuesday said that just under 17.9 million viewers tuned into Sunday’s show, which air...
Reflecting On Health Insurance Providers Stocks’ Q4 Earnings: Progyny (NASDAQ:PGNY)
Quarterly earnings results are a good time to check in on a company’s progress, especially compared to its peers in the same sector. Today we are looking at Progyny (NASDAQ:PGNY) and the best and worst performers in the health insurance providers industry.
Douglas County Commissioner Mary Ann Borgeson reflects on 32 years in politics
As Women’s History Month highlights the achievements of women in society and culture, one woman has served the metro area community for more than three decades.
Ali Larijani, a Top Iranian Politician and Emissary, Is Dead at 67
Mr. Larijani, the top national security official and a confidante of the former supreme leader, expertly navigated Iran’s internal politics and led the brutal crackdown on protests this year.
Two men have been charged with running a fraudulent contracting business in Lower Merion
The Lower Merion Police Department is urging anyone who believes they were a victim of contractor fraud by Jake Fox and Scott Bradley to contact law enforcement.
Our family had $214,000 in debt. Here's what we changed.
Our debt came from normal expenses. We sold our truck, stopped eating out, and are paying off $100,000 of our $214,000 debt this year.
The glaring problem with RFK Jr.’s push for more nutrition education
Teaching doctors in training about nutrition will do little if patients cannot access healthy food.
Court filings shed light on McGlinchey debts, assets as firm is dissolved in bankruptcy
Documents filed in the McGlinchey Stafford bankruptcy case shed new light on the New Orleans firm’s financial situation in the wake of its surprise decision early this year to shut
The LYCRA Company to Eliminate More than $1.2 Billion of Debt through Prepackaged Restructuring Process, Positioning Business for Long-Term Financial Stability and Growth
WILMINGTON, Del., March 17, 2026--The LYCRA Company to Eliminate More than $1.2 Billion of Debt through Prepackaged Restructuring Process
Chelsea vs PSG – Match preview and team news
Chelsea welcome Paris Saint-Germain to Stamford Bridge tonight, needing a miracle to overturn a daunting three-goal deficit against the Champions League holders.The Blues arrive following a bruising 5...
Dodgers vs. Brewers game chat
Dodgers take on the Brewers on Monday afternoon. Monday game info
Long-running entertainment show canceled by NBC
The show will end its run after nearly 30 years.
Trump insisted he didn’t need allies’ help in Iran. Now he’s demanding they step in
NATO allies face calls from Trump to help address the Strait of Hormuz crisis, raising doubts about the US president’s claims the Iran war is going well after he previously insisted he didn’t need their help.
Samsung admits 'some variation' will be seen on the Galaxy S26 Ultra's screen brightness due to Privacy Display — but it should be 'negligible'
A confirmation and reality check
NBC cancels 4 shows, including one that’s been on the air for 30 years
NBC has pulled the plug on 4 shows, including an iconic show that's been on the air for nearly 30 years
Emails show back‑and‑forth over latest Rick Jackson ad
An AJC‑obtained email chain shows months of back‑and‑forth that led to Republican Rick Jackson’s latest TV ad targeting Lt. Gov. Burt Jones.
A strange twist in the universe’s oldest light may be bigger than we thought
Scientists studying a mysterious effect called cosmic birefringence—a subtle twist in the polarization of the universe’s oldest light—have developed a new way to reduce uncertainty in how it’s measured. This faint rotation in the cosmic microwave background could point to entirely new physics, including hidden particles such as axions and clues about dark matter or dark energy.
The New York Times
Gun-rights activists are a long-established force in Republican politics. But no candidate with a credible chance of reaching Congress has had a profile quite like Brandon Herrera, who has built a...
Children's Healthcare CEO to retire after 40 years with hospital
Donna Hyland will step down as CEO and will be succeeded by Patrick Frias.
GN Store Nord to sell hearing business to Amplifon for $2.6 billion
GN Store Nord has agreed to sell its Hearing business to Italy's Amplifon for 17 billion Danish crowns ($2.6 billion) on a cash-free and debt-free basis, the Danish hearing aid maker said on Monday.
China woman uses AI-made man to lecture on respecting science, rejecting superstition
Non-existent retired professor who ‘lectures’ on parent-child relationships gathers online support from 200,000 followers.
Javier Bardem Condemns ‘Trump and Netanyahu’ for ‘Another Illegal War’ at a Very Political Oscars
Host Conan O'Brien was subtle with his comments, Jimmy Kimmel less so, and the nominated films themselves carried a political charge.
March Madness 2026: We had AI pick every game of the men's NCAA tournament bracket. Here's who won
Scientists discover what really happens during sourdough fermentation
New research shows that sourdough fermentation does more than make bread rise—it transforms wheat fibers in unexpected ways. Scientists found that enzymes already present in wheat, activated by the sourdough’s acidic environment, break down key fibres called arabinoxylans. This process may influence the bread’s texture, digestibility, and flavor. Some microbes even create buttery or subtly sweet notes that give sourdough its distinctive taste.
Scientists just discovered a tiny signal that volcanoes send before they erupt
A new detection method called “Jerk” could dramatically improve how scientists forecast volcanic eruptions. By using a single broadband seismometer, the system can detect extremely subtle ground movements caused by magma pushing underground—often hours before an eruption begins. Tested for more than a decade at the Piton de la Fournaise volcano on La Réunion, the tool successfully predicted 92% of eruptions between 2014 and 2023, sometimes giving up to eight hours of warning.
NCDHHS launches statewide online mental health bed registry tied to 988 hotline
The North Carolina Department of Health and Human Services has announced a statewide online mental health bed registry aiming to reduce wait times.
Iran Foreign Minister Says Mojtaba Khamenei Is in “Perfect Health” After Trump Doubts
Iranian Foreign Minister Abbas Araghchi wrote on his Telegram channel that “the Leader of the Revolution is in perfect health and is ful ...
2026 MLB Team Preview Series: Cincinnati Reds
The worst team to make last year’s playoffs, the Reds can once again compete as a fringe contender if things break right
Trump is searching for an endgame to the Iran war
Senior officials privately expressed doubt the Trump administration can achieve the overthrow of Iran's government and the destruction of its nuclear program through military means.
Celtics' Joe Mazzulla Praises Jaylen Brown's Subtle Impact In Win
Sometimes, it's the little details that make the biggest impact
Two weeks into war with Iran, Trump has been knocked back on his political heels
Two weeks of war in Iran has President Donald Trump increasingly knocked back on his political heels
Scientists tested vitamin D for COVID and found an unexpected long COVID clue
A major clinical trial has delivered an unexpected twist in the search for ways to fight COVID-19 and its lingering effects. Researchers at Mass General Brigham found that taking high doses of vitamin D3 did not make COVID-19 infections less severe or reduce hospital visits. However, the study uncovered a subtle but intriguing signal suggesting that people who consistently took vitamin D supplements might be slightly less likely to develop long COVID symptoms weeks after infection.
Officers searching for two people who robbed Hopewell business
Officers said the pair held the employee at gunpoint.
Lobbyist tied to pardon from Trump charged with attempted extortion
Federal prosecutors charged a lobbyist with trying to extort a former client and his son to recover half a million dollars in debt, according to court filings.
The Players Championship 2026 purse, payouts: Ludvig Åberg holds 3-shot lead entering Sunday at TPC Swagrass
Duke player: Harassment by sports betting losers is out of hand
Duke men's basketball player Isaiah Evans said prop bets aren't healthy for the sports. He told WRAL's Brian Murphy that he and his Blue Devil teammates hear from people about their prop bets, including immediately after Saturday's ACC Tournament semifinal, and it is not helpful, even harrassment.
Linux Finally Catches Up to Windows with a Game-Changing Performance Feature
For years, the Linux kernel’s scheduler has been world‑class at balancing loads, yet it missed a crucial, cache‑aware instinct. In modern multi‑core systems, that gap can turn into measurable latency, especially when threads bounce between cores that don’t share the same cache. A new upstream feature, often called Cache Aware Scheduling, is now set to change that equation. A cache‑savvy scheduler arrives At the heart of any OS, the scheduler decides which thread runs where and for how long. In modern CPUs, small private caches (L1 and L2) sit beside each core, while a larger Last Level Cache (LLC, typically L3) is shared among groups of cores. When a task migrates across LLC boundaries, its warm data may vanish from the cache, forcing slower trips to main memory. Cache Aware Scheduling keeps related tasks close to their shared LLC, reducing destructive migrations. By respecting cache topology, the kernel minimizes cold‑start penalties and preserves locality that many workloads desperately need. The result is less thrashing, fewer memory stalls, and more consistent throughput. "Keep tasks close to their data, and the system will keep performance close to its peak." Why this narrows the Windows gap Windows has long leaned on topology‑aware, cache‑sensitive heuristics, especially since the Windows 10 era. That advantage helped Microsoft handle hybrid designs with P‑cores and E‑cores, plus complex cluster and NUMA layouts. With cache awareness integrated upstream, Linux brings parity to this vital dimension, without sacrificing its trademark flexibility. The Linux approach remains deeply configurable, reflecting the ecosystem’s breadth across servers, desktops, and embedded devices. It layers atop existing NUMA‑balancing and energy‑aware logic, refining placement rather than reinventing the wheel. Crucially, it aligns scheduling with the hardware’s real shape, not just with abstract CPU counts. Real‑world gains and who benefits Early tests on Intel Sapphire Rapids platforms point to gains in the 30–45% range for select workloads. Those wins appear in cache‑sensitive tasks like in‑memory analytics, high‑thread compilation, and microservices with tight working‑sets. Games and latency‑bound engines can also feel steadier frame‑times, especially when threads share hot assets. The benefits extend to AMD’s 3D V‑Cache parts, where keeping threads near enlarged cache slices prevents needless misses. Hybrid x86 designs with performance and efficiency cores further profit when cache and core roles are scheduled in concert. Even handhelds running SteamOS can squeeze more out of limited power, translating cache locality into smoother play. Key advantages include: Lower end‑to‑end latency Fewer expensive misses to RAM Better multi‑socket and NUMA behavior Improved energy efficiency More predictable QoS under mixed loads Stronger scaling on dense servers Caveats, tuning, and rollout No scheduler change is purely free, and trade‑offs still exist. Favoring locality can reduce cross‑cluster balance if limits are set too tight. Likewise, fairness and utilization must remain healthy, especially under heterogeneous, bursty workloads. Linux’s implementation is designed to be measured and tunable, not a blunt instrument. It cooperates with energy‑aware scheduling for mobile efficiency, and with NUMA‑balancers on big iron. Expect architecture‑specific refinements as vendors surface richer topology hints and cache‑sharing maps. Upstream integration has begun, with broad distribution adoption likely over the next cycles. Many users will encounter the change through standard kernel updates in 2025–2026, depending on distro cadence. Server‑class kernels may enable or tune it sooner for targeted fleets where cache locality is money in the bank. How to think about performance impact Cache Aware Scheduling amplifies gains when your workload is both CPU‑bound and cache‑sensitive. Think tight inner loops, hot code paths, and datasets that fit snugly in shared LLC. It’s less dramatic for I/O‑bound services or memory‑hungry tasks that blow past cache capacity. Still, even modest locality improvements often translate into smoother tail‑latency, which is where user experience and SLAs typically break. Developers can further help by pinning related threads, batching work, and aligning data to reduce cross‑cluster chatter. The scheduler’s new awareness works best when applications expose good hints. The bottom line By understanding and honoring cache topology, Linux removes a subtle yet costly bottleneck. The kernel’s smarter placement keeps hot data hot and work near where it belongs. That narrows a long‑standing gap with Windows, while preserving the openness and tunability Linux champions. For gamers, creators, and operators, the payoff is practical: more consistent frames, faster builds, and snappier services. For the ecosystem, it’s another step toward hardware‑savvy scheduling that turns transistor complexity into real‑world speed. And for Linux itself, it’s a timely upgrade that matches today’s silicon with tomorrow’s expectations.
Lawsuit says Manolo’s Bakery lost more than $50k in business during ‘Operation Charlotte’s Web’
That fight for survival hasn’t stopped Betancur from smiling and greeting his customers.
BTS Is Ready For Business In New ‘Arirang’ Artwork
BigHit Entertainment has shared the "Arirang" artwork, which the members of BTS looking dapper, and rather serious, in suits.
Cowboys DT headed to 49ers for 3rd-round pick
Cowboys defensive tackle Osa Odighizuwa has agreed to join the San Francisco 49ers in exchange for a 2026 third-round pick in this year's NFL Draft.
Buzzfeed has ‘substantial doubt’ it can stay in business
Buzzfeed, the digital media company that took the mid-2010s by storm, said on Thursday it has “substantial doubt” about its ability to continue as a business.
Flooding closes roads in Marshall County, hurting business and raising detour concerns
Tuesday's storms are still causing issues in our area.Flooding across Marshall County is causing issues for people trying to get to their destinations as well a
Trump pushes GOP to focus on health care in midterms, which would be fine with Democrats
The president told GOP lawmakers this week: “We can own the issue.” Republicans shouldn’t get their hopes up.
Trump doesn't recognize the debt we owe veterans
At a time when our forces are in harm's way, the people who care for them at home through Veterans Affairs are being stretched thinner and thinner.
Kathie Lee Gifford Says She Doesn’t Judge Anyone — But Has A Note About LGBTQ
"They've really got to stop with that," the retired morning TV personality said.
NFL free agency tracker: Each team's notable departing free agents, signings, trades as league's new year begins
Kathy Ireland sues business managers for allegedly swindling multimillion-dollar fortune
Kathy Ireland accused her former team of fumbling her multimillion-dollar fortune, according to documents obtained by Fox News Digital.
NFL free agency tracker: Each team's notable departing free agents, signings, trades as league's new year approaches
Medical Debt Associated with Deferring Dental, Medical, and Mental Health Care | Johns Hopkins Bloomberg School of Public Health
Deferred care due to medical debt consistently high across all types of insurance, with dental care the most sensitive to medical debt.
Samsung Galaxy S26 Ultra review: This is too much phone
This might be the year I switch to Android.
Introducing new Courier & Press sportswriter Markos Tsegaye
The Courier & Press is excited to welcome Markos Tsegaye to the sports staff. Get to know more about our newest employee here.