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Carbon emissions now more than double the planetary boundary, analysis finds
Earth is not infinite. Pollution beyond certain levels threatens the climate and ecosystems. To prevent this, scientists have proposed planetary boundaries, defining the safe operating limits of the Earth ...
Abry Brothers has been keeping it on the level for 7 generations, shoring up a sinking city
Abry Bros.has been shoring and leveling structures in New Orleans for nearly 200 years. New cost pressures and insurance regulations are making it harder than ever for the sixth- and seventh-generation owners.
Loaded Pirates Soar Up MLB Pipeline’s 2026 Farm System Rankings
The Pittsburgh Pirates are arguably the most improved team in baseball this year, both at the Major League and Minor League levels. At the MLB level, the Pirates have the second-best FanGraphs playoff odds in the NL Central after finishing last in their division last year. They appear poised for a big leap, especially at […]
Colorado’s congressional redistricting proposal could flip three Republican House seats
A Democrat-backed proposal to redraw Colorado’s congressional map for the 2028 election could flip three Republican districts. The proposal, introduced by a group called Coloradans for a Level Playing Field, is yet another development in a national redistricting debate after President Donald Trump called to redraw U.S. House districts. An analysis of the proposal in […]
Missing From Apple's Announcements: iPad 12 With Apple Intelligence
In his newsletter over the weekend, Bloomberg's Mark Gurman said Apple was likely to announce at least some but possibly not all of the following products between March 2 and March 4: the iPhone 17e, MacBook Pros, MacBook Airs, updated entry-level iPad and iPad Air models, and a lower-cost MacBook with an iPhone chip. As it turns out, Apple announced nearly all of those products, with the sole exception being an updated entry-level iPad.
Become the Butcher in Season of Slaughter
Become the Butcher and turn your enemies into Fresh Meat in Season of Slaughter, and play as the Paladin for free up to Level 25.
Hockey mom conflicted over women's team skipping White House visit
I've seen my daughter's hockey team receive less recognition and resources than the boys who play. The sport needs representation on a national level.
Study finds sea levels are higher than we thought, placing millions more at risk
Climate change's rising seas may threaten tens of millions more people than scientists and government planners originally thought because of mistaken research assumptions on how high coastal waters already are, a new study said.
Preston sports and community hub 'to tackle health inequalities'
The hub will seek to tackle low levels of exercise and significant deprivation in parts of Preston.
Browns extend tenders to six different Exclusive Rights Free Agents
NFL free agency is set to begin next week, but the Browns are tendering ERFAs ahead of next week's extravaganza.
KeyBank CIO Amy Brady steps down to “focus on her health and wellbeing”
KeyCorp attributed the move to “personal health considerations,” with no additional details currently available to the public.
Scientists have been underestimating sea levels
Our coasts are more vulnerable than we realized.
Sea Levels Are Higher Than Many Scientists Think, New Study Shows
Researchers found that a majority of studies on coastal sea levels underestimated how high water levels are, and hundreds of millions of people are closer to peril than previously thought.
Popular fruits and vegetables linked to higher pesticide levels
A sweeping new study reveals that what’s on your plate may directly shape the pesticides circulating in your body. Researchers found that people who eat more fruits and vegetables known to carry higher pesticide residues—such as strawberries, spinach, and bell peppers—also have significantly higher levels of those chemicals in their urine. While produce remains a cornerstone of a healthy diet, the findings highlight how everyday food choices can drive real-world exposure to substances linked to cancer, hormone disruption, and developmental harm.
Browns announce completed coaching staff under new HC Todd Monken
The Browns are all staffed up, and Todd Monken has his coaching staff nailed down.
Cavs score vs Pistons. Injury report, live game updates, highlights
The Cleveland Cavaliers face the Detroit Pistons and former Cavs coach J.B. Bickerstaff for the final time during the 2025-26 NBA regular season.
War Is In Your Pocket: The Mental Health Toll On Women
From Gaza, to Isreal, to Iran, constant social media exposure to conflict is reshaping women’s stress and anxiety levels.
Small Businesses Hold Steady, but See a Rocky Road Ahead
Small businesses maintained steady performance in 2025, but a Cleveland Fed survey shows optimism for 2026 has faded as rising tariff costs squeeze margins.
How to watch Cleveland Cavaliers vs. Detroit Pistons on Rock Entertainment Sports Network
The Cleveland Cavaliers are back Tuesday on the Rock Entertainment Sports Network.
Scientists find the genetic switch that makes pancreatic cancer resist chemotherapy
Scientists have identified a crucial molecular switch that decides whether pancreatic cancer cells resist chemotherapy or respond to it. The key player, a gene called GATA6, keeps tumours in a more structured and treatable form—but it gets shut down by an overactive KRAS-driven pathway. When researchers blocked that pathway, GATA6 levels rebounded and cancer cells became more sensitive to chemo. The discovery could help turn some of the toughest pancreatic tumours into ones doctors can better control.
The cost of chaos at the CDC
Confusion at the federal level and funding cuts are devastating local health departments.
There were 13 full-service public health clinics in L.A. County. Now there are 6
On Feb. 27, the L.A. County Department of Public Health eliminated services at six of its 13 free clinics, citing funding cuts at the federal, state and local levels.
What's Next for Browns After Trading for Tytus Howard?
With Tytus Howard joining the Cleveland Browns via trade, key opportunities to continue filling out the o-line loom large in the coming weeks
Apple introduces MacBook Pro with all‑new M5 Pro and M5 Max, delivering breakthrough pro performance and next-level on-device AI
Cleveland Browns hit an ‘exciting milestone’ in stadium project
Construction crews started to dig the hole on Monday that will eventually become the sparkling indoor stadium.
State eliminates 8 applicants seeking money for sports facilities upgrades and construction
14 sports facility projects across Ohio, including 3 in Cleveland, are seeking a combined $689 million
The science behind smell
Meet Edgar Orellana Reyes and Abbie Deeth (aka Gail)—a research duo at Macalester who prove that high-level science is better with a "bestie" by your side. The two worked in the lab of Professor Michelle Tong, Neuroscience, through Macalester's Collaborative Summer Research Grant. While they’ve been "locked at the hip" since they met, they bring
DC Health lifts Potomac River recreation advisory after tests show safe E. coli levels
The District Department of Health has lifted its recreational advisory for the Potomac River effective immediately, water quality testing showed bacterial level
Browns 2026 NFL draft picks after OT Tytus Howard trade
The 2026 NFL draft is around the corner with the Cleveland Browns having 9 draft picks after the Tytus Howard trade
US manufacturing grows steadily in February, input prices surge
U.S. manufacturing activity expanded steadily in February, but a measure of prices paid by factories for inputs rose to the highest level in nearly 3-1/2 years, highlighting upside risks to inflation amid import tariffs even before a U.S.-led attack on Iran sent oil prices higher.
Cleveland Clinic Establishes Women’s Integrated Sports, Exercise and Research Center
New Center will support the health, wellness and performance goals for female athletes at any age or ability
48-Hour Oatmeal Diet Could Cut Cholesterol Levels For Weeks, Study Shows
But there are caveats.
Tiny Public Assembly Theatre stages 3 new 12-minute plays a month
The tiny Public Assembly theater company is taking community theater to the next level by developing and performing three one-act plays per month. Seeing a show is the only prerequisite to submitting, and you might be surprised by the Hollywood star power that shows up.
Scientists reveal why a popular anti-aging compound may also fuel cancer
Polyamines—natural molecules found in every living cell—have become stars in the longevity world for their ability to boost cellular cleanup and support healthy aging. But there’s a dark twist: high levels of these same molecules are consistently seen in cancer, where tumors grow aggressively.
Global webinar on core public health capacities to conduct ship inspections and issue ship sanitation certificates
Ships cross borders every day, connecting countries and serving as a backbone of the global economy. However, outbreaks onboard can disrupt maritime traffic, leading to significant economic and operational negative consequences. Without strong public health capacities to detect, prevent, and respond to public health risks on board ships, maritime travel can also become a pathway for the spread of infectious diseases. To support countries in strengthening these capacities, the World Health Organization (WHO) convened a two-day webinar on 11–12 February, bringing together more than 700 ship inspectors, port health officers, and public health authorities, primarily from the African, Eastern Mediterranean, and European Regions. The webinar came at a pivotal time. With the amended International Health Regulations entering into force on 19 September 2025, the need to focus on public health preparedness has never been greater. Strengthening public health capacities at borders, including onboard conveyances, is a cornerstone of global health security and central to the amended IHR.“The high level of attendance and active participation throughout the two days of the webinar highlighted the growing demand for technical guidance and capacity-building support in ship inspection and issuance of ship sanitation certificates”, said Dr Ninglan Wang, Head of the Borders, Mass Gatherings and Health Protection Measures (BMM) Unit at the Health Emergency Preparedness Department at WHO headquarters. “The dynamic interactions among experts and countries underscored the value of continued cross-border collaboration in the maritime sector and knowledge exchange in this area”. Conducting regular public health inspections on board ships for the issuance of ship sanitation certificates (SSCs) in accordance with the IHR requirements is crucial for ensuring that ships meet specific health standards, thereby minimizing the risk of the international spread of diseases via maritime traffic. These certificates, mandated by the IHR, require ports to have trained personnel who can identify and control public health risks on board vessels and apply recommended control measures. This standardized global procedure not only ensures compliance with the IHR but also promotes consistency in health practices across ports worldwide. SSCs are the globally-recognized tool used to prevent and control known public health risks on ships, providing a common way to register and communicate public health events and measures taken on board between all stakeholders involved in this process, including public health authorities in ports and ship operators. Only SSCs issued by ports authorized by national authorities to issue such certificates are considered valid. As per the IHR, all States Parties are required to send to WHO their list of authorized ports (available here) and to keep it updated. However, many Member States continue to face practical challenges, such as limited resources, high staff turnover, and competing priorities. These realities underscore the value of platforms such as this webinar, which foster collective learning, peer-to-peer exchange, and practical solutions to help countries build and sustain the capacities required under the IHR.Over the two days, participants engaged in presentations and discussions covering a wide range of technical and operational topics, such as the overarching international legal framework governing ship sanitation; considerations for pre-inspection planning; risk assessment factors by type of vessel; the completion and issuance of SSCs and evidence report forms; or practical insights on the inspection of various technical areas, such as food safety, medical facilities, water systems, or vector control, among others. In addition, public health authorities from the Netherlands, Morocco, and Tanzania shared case studies to showcase their practical application of these IHR requirements in their respective countries. Given its success, WHO plans to replicate similar sessions in the future to reach additional time zones and regions and cover other pressing border health-related topics, ensuring that Member States can continue benefiting from these opportunities to share knowledge and expertise.
Do Americans support Iran strikes? Here's what new poll says
A new Reuters/Ipsos poll finds low levels of support for the U.S.-Israel strikes on Iran that killed the country's supreme leader.
“Entry-Level PC Segment Will Disappear by 2028,” Says Gartner, as Soaring Memory Costs Start to Cripple Manufacturers
PC manufacturers won't find it viable to offer hardware to gamers at 'entry-level' prices, as memory costs have reached unprecedented levels.
Deshaun Watson expected to start for Cleveland Browns in 2026
The NFL Scouting Combine is coming to a close, and there have been a number of great performances recorded. There have also been some interesting reports coming out of the combine. Of the teams at the combine, the Cleveland Browns…
New iron nanomaterial wipes out cancer cells without harming healthy tissue
Scientists at Oregon State University have engineered a powerful new nanomaterial that zeroes in on cancer cells and destroys them from the inside out. Designed to exploit cancer’s unique chemistry—its acidity and high hydrogen peroxide levels—the tiny iron-based structure sparks not one but two intense chemical reactions, flooding tumors with cell-damaging oxygen molecules. This dual attack overwhelms cancer cells with oxidative stress while sparing healthy tissue.
New iron nanomaterial wipes out cancer cells without harming healthy tissue
Scientists at Oregon State University have engineered a powerful new nanomaterial that zeroes in on cancer cells and destroys them from the inside out. Designed to exploit cancer’s unique chemistry—its acidity and high hydrogen peroxide levels—the tiny iron-based structure sparks not one but two intense chemical reactions, flooding tumors with cell-damaging oxygen molecules. This dual attack overwhelms cancer cells with oxidative stress while sparing healthy tissue.
Old Town Albuquerque property owners weigh forming a Business Improvement District
Historic Old Town Association president J.J. Mancini says a BID — a mechanism through which property owners pool resources to fund services such as cleaning, maintenance, security and marketing — could take the historic neighborhood's goals and visions 'to the next level.'
4 Costco Tablet Accessories That Will Level Up Your iPad
Top Costco iPad accessory picks include the Apple Pencil Pro, Magic Keyboard, a 20,000 mAh power bank, and the latest AirTags for tracking.
Winners and Losers: Cleveland Cavaliers at Detroit Pistons
The Cavs came up short on the road.
Brad Stevens deserves praise for the Boston Celtics' recent success
Brad Stevens continues to build high-level rosters
Trump suggests U.S. could have 'friendly takeover of Cuba'
President Donald Trump said Friday that Secretary of State Marco Rubio was negotiating at a high level with the Cuban government.
NC State trying to extend Notre Dame's 'season from hell'
NC State's last two games could not have been much further apart in terms of performance level.
To succeed with AI, leaders must prioritize safety when driving transformation
Dr. Paul A. Testa, CHIO at NYU Langone Health, says artificial intelligence demands the same level of institutional commitment, governance and cultural investment that the best health systems brought to EHR adoption.
Pistons vs Cavaliers preview: Send a message to Cleveland’s bigs
Unfortunately, these potential Detroit Pistons statement games keep turning into who’s available games. The Pistons take on the new-look Cleveland Cavaliers tonight, but this won’t be the team Detroit might see in a seven-game series. Cleveland’s best player, Donovan Mitchell, is out tonight with a groin designation. Cleveland’s new addition, James Harden, is questionable with […]
See details for all the Ohio sports stadium & arena projects seeking state money
Cavs, Guardians, Bengals, Blue Jackets are far from alone in seeking help for stadium upgrades
Pound Hits Two-Month Low Versus Euro as UK Politics Spurs Hedges
The pound fell to its lowest level against the euro in more than two months and traders paid for protection against further losses after a special election in Manchester signaled trouble ahead for the governing Labour Party.
Why The Narrative Around Accel Entertainment (ACEL) Is Shifting As Valuation Holds And Leadership Evolves
The fair value estimate for Accel Entertainment holds steady at $15.17, with no change to the target level in the latest update. Bullish and bearish analysts are reading this unchanged target differently, with some highlighting it as support for the current thesis and others pointing out that it leaves limited room if execution does not fully match expectations. As you read on, you will see how this stable $15.17 target fits into the evolving narrative around leadership changes, risk inputs,...
No Offense: Devils Drop 5th Straight
There was a point, about midway through Thursday’s 4-1 loss to Pittsburgh, where it kind of, sort of felt as if the Devils might manage to salvage a point, maybe even steal two from the Penguins. Paul Cotter had scored, an almost water-to-wine level miracle. Jacob Markstrom was playing as well as he has at […]
Election observers raise concerns over secret ballot breaches at Gorton and Denton byelection
Democracy Volunteers say they saw 32 cases of apparent collusion – the highest levels in its 10-year history
Cavaliers look to keep up with East-leading Pistons
The Cleveland Cavaliers hold the fourth spot in the Eastern Conference, but according to oddsmakers and bettors, they're the current favorite to represent the conference in the NBA Finals.
Cuyahoga County is changing how first responders handle mental health crises
A new fund will help municipalities pair public safety professionals with behavioral health specialists to respond to residents in crisis.
Executives accused of defrauding veteran-owned business by giving themselves unauthorized raises
GREENWOOD, Ind. — Two high-level executives at a veteran-owned business in Greenwood have been fired and face criminal charges after allegedly giving themselves unauthorized raises and pay advancem…
Florida Department of Health cuts thousands of dollars in funds from HIV and AIDS drug program
Starting Sunday, the state will cut its subsidies for the AIDS Drug Assistance Program (ADAP), and funds will only be available for people at or below 130% of the federal poverty level, a drop from 400%.
Premier League chief, union boss warn of threat to star players over expanding football calendar
The 2026 World Cup is just around the corner, and PL chief executive Richard Masters said the sport 'cannot rely' on star players to maintain their level with the current calendar
Bedrock, Rock Entertainment Group unveil plans for 6,200-seat outdoor amphitheater on Cleveland riverfront operated by Live Nation
Diversified Protective Services Expands Executive Protection Services, Strengthening Security Support for the Entertainment and Film Industry
Diversified Protective Services, a premier security firm headquartered in Los Angeles, is proud to announce the expansion of its Executive Protection Services, with a specialized focus on the entertainment and film industry. As demand for discreet, high–level personal security continues to increase throughout Hollywood and the broader entertainment community, the company is positioned to deliver tailored protection solutions for actors, executives, production teams, and high–profile industry pro
Popular brain supplement linked to shorter lifespan in men
A massive study of more than 270,000 people has uncovered a surprising link between a common amino acid and how long men live. Researchers found that higher levels of tyrosine—an amino acid found in protein-rich foods and often marketed as a focus-boosting supplement—were associated with shorter life expectancy in men, potentially trimming nearly a year off lifespan.
The more you fear aging, the faster your body may age
Worrying about getting older—especially fearing future health problems—may actually speed up aging at the cellular level, according to new research from NYU. In a study of more than 700 women, those who felt more anxious about aging showed signs of faster biological aging in their blood, measured using cutting-edge “epigenetic clocks.” Fears about declining health had the strongest link, while concerns about beauty or fertility didn’t appear to have the same biological impact.
Sausalito looking for business to fill vacancies on Bridgeway
The city of Sausalito, deeply concerned about maintaining its world-class tourist image and warding off sea level rise, is planning to lure bigger retailers and restaurants without making it like every other place.
Trumbull health district recognized on a national level
Trumbull County Combined Health District was one of 19 health departments across the country recognized for high standards and services.
Todd Monken Non-Committal, But Optimistic About Browns' Current QBs
New coach Todd Monken embraces looming open competition for Cleveland Browns QB role, but sees promise with current options.
Missouri and Kansas families pay nearly 10% of their income on employer-provided health insurance
A new report found that nearly 10% of median household income in Missouri and Kansas goes toward deductibles and premiums. At that level, economists say those households are underinsured.
South Carolina Health Official 'Encouraged' by Sharp Two‑week Drop in Measles Cases
Feb 25 (Reuters) - South Carolina has reported lower cases of measles two weeks in a row, offering an encouraging sign that the outbreak may be easing, a state health official said in a briefing on Wednesday. "The hard work and long hours that frontline, often entry-level epidemiologists,
Meet the influencer Trump wants in charge of U.S. health
Wellness influencer Dr. Casey Means — a Stanford-trained physician and co-founder of Levels — is President Trump’s nominee for U.S. surgeon general.
Requests swamp Ohio sports stadium fund as Cleveland soccer joins rush
Bengals, Blue Jacks, Guardians, Cavs, Cleveland soccer facilities among those lining up for state help
Entertainment: Limelight venue & Survior 50
Limelight Hawaii, a six-thousand square foot space at the Ala Moana Hotel, can hold up to 700 people and features a massive LED screen, concert-level sound and lighting, and a full commercial kitchen and bar.
CVS Health put volume heavy and directionally bearish
Bearish flow noted in CVS Health (CVS) with 3,674 puts trading, or 1.5x expected. Most active are 2/27 weekly 74 puts and 2/27 weekly 73 calls, with total volume in those strikes near 2,800 contracts. The Put/Call Ratio is 1.51, while ATM IV is up nearly 2 points on the day. Earnings are expected on April 29th.Claim 50% Off TipRanks PremiumUnlock hedge fund-level data and powerful investing tools for smarter, sharper decisions Stay ahead of the market with the latest news and analysis and maximi
More Lower-Cost MacBook Details Surface Ahead of 'Apple Experience' Next Week
Apple is expected to unveil up to five new products next week, including a lower-cost MacBook, and a few more details about the laptop surfaced today. According to supply chain sources who spoke to DigiTimes, the entry-level MacBook will indeed be launching in March. The report said volume shipments of the laptop to Apple are projected to begin next month. Quanta Computer is expected to be the primary assembler of this new model, and Foxconn is expected to join in later.
The brutal business of the NFL: Martin Emerson Jr. and J.O.K. face uncertain futures after Browns’ combine re
Andrew Berry's carefully worded comments at the NFL Combine cast serious doubt on whether either beloved Browns player will suit up for Cleveland again.
Will Ethiopia be part of Israel’s ‘hexagon’ alliance rivalling its enemies?
Israeli President Herzog is in Addis Ababa days after high-level delegations from Turkiye and Saudi Arabia also visited.
Will team owner greed prevail over the public good in Ohio sports facility financing? Editorial
At a minimum, any publicly funded gilding of the Guardians’ and Cavs’ resources for facility upgrades should be paired with a required renegotiating of the facility leases to take local taxpayers off the hook for any further obligation to pay for repairs and upgrades, writes the editorial board of The Plain Dealer and cleveland.com.
[CROI 2026] aidsmap: The war on science: resisting and rebuilding at a crucial juncture
“We all knew Trump’s second term would be worse than his first. But few of us were prepared for the level of destruction – and the speed of it...”
The Health and Climate Benefits of Slow Living
Pick one day a week to slow down. It can lower stress levels—and your carbon footprint.
Opioid Overdose Deaths: National Trends and Variation by Demographics and States
Opioid overdose deaths fell sharply from 2023 to 2024 (79,358 to 54,045), driven largely by decreases in fentanyl-involved deaths. Even after these declines, deaths remained above 2019, the year before opioid deaths increased sharply during the pandemic.
Manipulating gene activity to reverse aging
By altering levels of molecules called transcription factors in mice, researchers were able to reverse some of the effects of aging.
Cleveland's next big sports destination: Cosm
The venue will serve as an anchor for Cleveland's riverfront development plan.
Trump Says General Caine Sees Easy Victory if U.S. Attacks Iran
The remarks differ from what Gen. Dan Caine, the chairman of the Joint Chiefs of Staff, is said to have told the president in high-level White House meetings.
Entry-Level Ferrari Ready To Lose Its Head Soon Enough
Prices for the Ferrari Amalfi Spider will likely start at around $270,000, if not a little more
Microplastics found in prostate tumors in small study
Plastic particles were found at higher levels in tumor tissue than nearby noncancerous tissue, raising questions about the role they may play in tumor development.
Prior authorization is a top health care burden, KFF poll finds
About 32% of Americans say prior authorization requirements are a major burden, more than billing confusion or finding appointments, according to the January 2026 survey.
Nationwide recall issued for popular supplement, consumer health risk: Return ASAP
The product is being recalled because it contains a higher level of a potent compound than is listed on the label, which poses a health risk.
This Gen Zer skipped university and built a six-figure dog walking business
As AI threatens entry-level jobs, some young people are starting their own businesses.
Dru Joyce Classic | April 10, 2026 | Greater Cleveland Sports Commission
Dru Joyce Classic returns to Cleveland! Cleveland is set to host one of the nation’s premier youth basketball events. From April 10-12, 2026, the Dru Joyce Classic will take over the I-X Center, bringing elite competition and a significant economic boost to Northeast Ohio. This three-day tournament is a cornerstone of the...
Like Trump nationally, incumbent Colorado Dems lose sight of what matters to everyday people
My years as a high-level radioactive waste manager took me in and out of Washington, D.C. frequently during the 1990s. Following Newt Gingrich’s successful 1994 ouster of the Democratic majority in Congress, following their 40-year reign, I was surprised many Democratic lobbyists were willing to acknowledge privately Newt’s win was probably a good thing. There […]
Looks like Samsung's Privacy Display trick won't remain exclusive for long
According to a new leak, Chinese smartphone brands are testing hardware-level privacy displays similar to Samsung's Galaxy S26 Ultra feature.
Which EU country is best at digital health records?
Most European countries have made progress in access to electronic health records. Despite this progress, there is still room for improvement. Low levels of digital health literacy in some countries remain another key challenge.
Shedeur Sanders Receives Major Praise From Fellow Browns' Rookie
Cleveland Browns standout linebacker Carson Schwesinger heaps praise on fellow rookie Sheduer Sanders
PRET for impact: Advancing pandemic preparedness in the Democratic People’s Republic of Korea
IN THE SPOTLIGHT PRET for impact: Advancing pandemic preparedness in the Democratic People’s Republic of KoreaThe Democratic People’s Republic of Korea (DPR Korea) is making significant progress in strengthening pandemic preparedness, with dedicated support from the WHO South‑East Asia Regional Office (SEARO) and the Pandemic Influenza Preparedness (PIP) Partnership Contribution (PC).Aligned with the WHO Global Influenza Strategy and the Pandemic Influenza Preparedness (PIP) Framework Partnership Contribution High‑Level Implementation Plan III (2024–2030), the country is strengthening its capacity to prepare for and respond to influenza and other respiratory threats. In early 2025, a core team from the Ministry of Public Health of the Democratic People’s Republic of Korea (DPRK) participated in a two‑day virtual workshop, which included a mini‑simulation exercise. The workshop was organized by WHO SEARO in collaboration with the Preparedness and Resilience for Emerging Threats (PRET) Secretariat at WHO headquarters and the WHO Country Office for the DPRK. Read more A REGIONAL CONSULTATION GUIDES WHO SEARO IN DEVELOPING A ROADMAP FOR IMPLEMENTING THE PREPPAREDNESS AND RESILIENCE FOR EMERGING THREATS (PRET) INITIATIVE BASED RESPIRATORY PATHOGEN PANDEMIC PREPAREDNESSInfluenza and other respiratory pathogens with pandemic potential continue to pose major public health risks globally. To strengthen regional preparedness and response, Member States of the WHO South‑East Asia Region (SEAR) convened in Colombo, Sri Lanka, to review and provide input on the draft Roadmap and Action Framework for Broad Respiratory Pathogen Pandemic Planning (2026–2031). Supported through the Pandemic Influenza Preparedness (PIP) Partnership Contribution (PC) funds, the proposed roadmap aims to advance robust, integrated preparedness and response capacities for influenza and other respiratory threats across SEAR. This work is aligned with the Preparedness and Resilience for Emerging Threats (PRET) initiative and the SEAR Strategic Roadmap on Health Security and Health System Resilience for Emergencies Read moreSRI LANKA’S USE OF ANTIVIRALS TO REDUCE THE SEASONAL INFLUENZA BURDEN Sri Lanka is strengthening its influenza response by placing greater emphasis on rapid testing, timely treatment, and integration with maternal health services. With support from WHO, the country is building a stronger evidence base on the burden of influenza and the value of vaccination, advancing a holistic approach to protect vulnerable populations and enhance pandemic preparedness. To reduce hospitalizations and deaths from seasonal influenza, Sri Lanka is taking proactive steps to expand access to rapid diagnostic testing and ensure prompt initiation of treatment. National clinical guidelines recommend the use of oseltamivir for individuals at high risk of complications, helping prevent severe illness and shorten the duration of infection. This strategy not only saves lives but also supports local pharmaceutical production, contributing to a reliable supply of antivirals for both seasonal outbreaks and future pandemics.Read moreBHUTAN BOOSTS PANDEMIC INFLUENZA READINESS WITH PANDEMIC INFLUENZA PREPAREDNESS FRAMEWORK PARTNERSHIP CONTRIBUTION SUPPORTED TRAINING AND SIMULATIONSOriginally developed in 2012, the National Influenza Pandemic Preparedness and Response Plan (NIPPRP) has long served as Bhutan’s central framework for managing influenza threats. In 2024, the plan underwent a comprehensive update to reflect evolving global and regional guidance, lessons learned from the COVID‑19 pandemic, and new capacities developed under the PIP Framework. The revised NIPPRP is now more clearly aligned with Bhutan’s broader emergency and disaster risk management structures, ensuring a coordinated, whole‑of‑government approach to pandemic response. As part of efforts to strengthen national pandemic preparedness, Bhutan conducted three national‑level training sessions followed by simulation exercises on influenza pandemic preparedness and response at five sentinel hospitals between April and May 2025, with support from the PIP Partnership Contribution (PC). These activities brought together more than 140 health professionals and key partners from across the country, with a focus on operationalizing the updated NIPPRP and enhancing readiness at key frontline facilities. Read moreSTRENGTHENING INFLUENZA SURVEILLANCE: WHO BRINGS TOGETHER INFLUENZA EXPERTS FROM SOUTH-EAST ASIA AND WESTERN PACIFIC REGIONSThe World Health Organization (WHO) convened the 18th Bi‑regional Meeting of National Influenza Centres (NICs) and Influenza Surveillance for the WHO South‑East Asia and Western Pacific Regions from 9–11 September 2025. Hosted by the WHO South‑East Asia Regional Office (SEARO), the meeting brought together representatives from Member States, Territories, and Areas across both regions, alongside experts from the WHO Collaborating Centres for Reference and Research on Influenza in Australia and Japan, the WHO Collaborating Centre for Studies on the Ecology of Influenza in Animals in the United States, quadripartite partners (WOAH and FAO), and other technical counterparts. The consultation provided a platform to review progress, share experiences, and outline priorities for strengthening influenza and respiratory pathogen surveillance across the two WHO regions.Read moreNETWORKS AND TECHNICAL PARTNERSHIPSSTRENGTHENING PANDEMIC READINES: SOUTH-EAST ASIA ADVANCES UNITY STUDIES UNDER THE PANDEMIC INFLUENZA PREPAREDNESS INITIATIVEThe WHO Global Influenza Surveillance and Response System (GISRS) Investigations & Studies initiative, also known as Unity Studies, provides a standardized, globally coordinated framework to support these efforts. Originally developed for influenza and adapted during COVID-19, Unity Studies enable countries to conduct rapid, nationally led investigations and studies to assess transmissibility, severity, susceptibility, and intervention effectiveness. To better prepare for future influenza pandemics, WHO has recently launched a network of sites which will be ready to conduct these investigations and studies rapidly in the event of a pandemic, or epidemic of an emerging or re-emerging respiratory pathogen. The WHO South-East Asia Region now hosts six sites of WHO GISRS Unity Studies across the five countries including Sri Lanka, strengthening regional capacity for early pandemic investigations. From 13–16 July 2025 in Colombo, the Global Public Health Summit offered an opportunity to advance this agenda. Read moreSTRENGTHENING PANDEMIC PREPAREDNESS THROUGH UNITY STUDIES: REAL-WORLD APPLICATIONS FROM INDIA IN WHO’S SOUTH-EAST ASIA REGION As countries continue to strengthen their pandemic preparedness through investments in resilient health systems during the interpandemic period, the World Health Organization’s (WHO) Global Influenza Surveillance and Response System (GISRS) Investigations & Studies Global Initiative, Global Initiative, commonly known as Unity Studies, remains a vital framework for respiratory pathogen pandemic preparedness. These standardized epidemiological protocols enable countries to rapidly generate high‑quality data on transmissibility, infection severity, population immunity, and the effectiveness of public health interventions. To highlight how Unity Studies protocols are being adapted and applied in national settings, WHO Headquarters, together with WHO Regional Offices, including the WHO South‑East Asia Regional Office (SEARO), hosted a global webinar. The session showcased case studies from India and the United Kingdom (UK), demonstrating innovative approaches to respiratory virus surveillance and pandemic readiness. Read moreSTRENGTHENING REGIONAL INFLUENZA SURVEILLANCE AND PREPAREDNESS: WHO SEARO HOSTS HIGH-LEVEL WEBINAR AMID RISING H5 THREATS In response to the increasing detection of avian influenza A(H5) cases in humans globally and within the WHO South‑East Asia Region, the WHO Regional Office for South‑East Asia (SEARO) convened a regional webinar on 25 July 2025 to review preparedness mechanisms, strengthen surveillance pathways, and promote timely reporting of unusual respiratory events. The virtual session brought together more than 50 participants from Ministries of Health, National Influenza Centres (NICs), National IHR Focal Points (NFPs), WHO Headquarters, WHO Country Offices across the Region, and WHO Collaborating Centres (CCs) for influenza. The webinar provided an opportunity to share situational updates, discuss surveillance gaps, and reinforce coordination mechanisms critical for early detection and rapid response to avian influenza threats. Read moreOther Key PIP Updates (July-December 2025)MEMBER STATES:Bangladesh drafted and conducted a series of Core Group Meetings in 2025 to review and update the National Pandemic Preparedness and Response Plan for Respiratory Pathogens. In addition, the country carried out Rapid Response Team (RRT) trainings on seasonal and avian influenza and other re‑emerging infectious diseases. Bangladesh also updated its epidemiological data‑training programme for physicians at sentinel surveillance sites, using a revised epidemiological data‑collection tool.Bhutan revised and updated its National Influenza Pandemic Preparedness and Response Plan (NIPPRP) in 2025 and developed a national Standard Operating Procedure (SOP) for influenza outbreak management. DPR Korea conducted a nationwide simulation exercise in July 2025 to support the update of its National Influenza Pandemic Preparedness Plan (2019). This followed a PRET‑based virtual orientation and mini‑simulation exercise held in May 2025 by SEARO and the WHO PRET Secretariat. The comprehensive exercise, conducted across central and provincial levels, assessed strengths and gaps in pandemic influenza preparedness and response. The feedback gathered has been incorporated into the revised draft plan to address identified weaknesses and strengthen overall readiness.India conducted a targeted nationwide online re‑orientation training on review and updates to the influenza portal for all State Surveillance Officers (SSOs) and relevant officials using the Integrated Health Information Platform (IHIP). The training emphasized correct marking and reporting of influenza samples as “unsubtypable” or “not subtyped” where applicable, to ensure accurate national surveillance.Maldives conducted simulation exercises in three atolls based on its existing National Pandemic Preparedness and Response Plan (NPPRP). The country plans to conduct similar exercises in three additional atolls after updating the NPPRP in 2026. In addition, Maldives conducted training on FluID and FluMart as part of a broader data‑management training package for Ministry of Health and Health Protection Agency officials, aimed at improving routine reporting to WHO platforms and the DHIS2 system.In Myanmar, technical support was provided to the National Influenza Centre (NIC) through dedicated human‑resource support (January–December 2025) to sustain data management and laboratory detection capacity for influenza and other emerging and re‑emerging respiratory viruses. This support also included strengthening genomic sequencing capacity.Nepal conducted a consultative workshop on the National Pandemic Preparedness and Response Plan (NPPRP) in July 2025. The workshop engaged key stakeholders from multiple sectors to review lessons from past pandemic responses, assess current mechanisms, and gather critical inputs for strengthening national preparedness. Key recommendations included revising the 2019 NPPRP and developing an updated Influenza Pandemic Preparedness Plan aligned with emerging risks, national priorities, and relevant international frameworks. Nepal also held a two day workshop dedicated to advancing the National Action Plan for Genomic Surveillance, aimed at reinforcing the country’s capacities for early detection and monitoring of emerging respiratory pathogens.Sri Lanka received the final report from WHO on the feasibility assessment for conducting an Influenza Burden of Disease (BoD) study in the country. The assessment, conducted from 28 April to 9 May 2025, included a desk review of existing data sources, document review, visits to sentinel surveillance sites, and key informant interviews. The study identified critical data sources required for a future BoD assessment, as well as their availability and quality. Officials from the Epidemiology Unit, the National Influenza Centre (NIC), and SARI/ILI sentinel hospitals across the country participated in the assessment.Timor Leste conducted on‑the‑job training and monitoring activities at two sentinel surveillance sites to strengthen surveillance and laboratory capacity for the detection of SARI, ILI, ARI, and other respiratory infections. REGIONAL OFFICE:SEARO conducted a Member States Consultation on the first draft of the Regional Roadmap and Strategic Action Framework for implementing WHO’s PRET‑based broad respiratory pathogen pandemic planning for 2026–2031. The consultation took place on 29–30 October 2025 during the final two days of the Regional PIP PC Annual Review and PRET Meeting in Colombo, Sri Lanka. Participants included representatives from Member States, WHO Country Offices, WHO SEARO, WHO Headquarters, partner agencies, and invited multidisciplinary technical experts. They reviewed the draft and provided detailed feedback, which has since been incorporated into a revised version. The consultation helped shape a shared regional vision for robust, PRET‑aligned pandemic preparedness, building on country‑level progress, addressing existing gaps and challenges, and aligning with global and regional health security frameworks. The publication is planned for release during the SEAR regional committee in 2026.SEARO documented the evolution of the National Influenza Pandemic Preparedness Planning process in the Region, tracing its development from its origins as a planning tool for responding to avian influenza outbreaks in 2006, through the experiences of the 2009 and 2019 pandemics, to the current status. The document outlines the way forward for respiratory pathogen pandemic planning across all 10 SEAR countries, aligning future national plans with WHO’s PRET Framework for broad respiratory pathogen pandemic preparedness.The Infectious Hazard Management (IHM) Unit has drafted the WHO South‑East Asia Regional Guidance on Influenza Prevention and Control, aligned with the Global Influenza Strategy and other regional initiatives. The draft is currently under review. Although this technical product was developed in response to a request from the Ministry of Public Health of the Democratic People’s Republic of Korea (MoPH‑DPRK), SEARO is finalizing it for use not only in DPRK but also across all Member States in the Region.The Immunization and Vaccine Development (IVD) Unit, in collaboration with WHE/SEARO, completed a regional landscape analysis on key barriers, challenges, and opportunities for the introduction of seasonal influenza vaccination in WHO South‑East Asia Regional (SEAR) countries.Additionally, the Immunization and Vaccine Development (IVD) Unit has completed a regional landscape analysis of influenza vaccine procurement systems across the WHO South‑East Asia Region (SEAR).KEY MEETINGS AND PUBLICATIONSMEETINGS:Six-month progress review of the implementation of the PIP-PC workplans in SEAR, focusing on Outputs 1 and 2 for the period January to June 2025, and held virtually across three sessions on 4, 8, and 10 July 2025. Read moreAnnual Regional Meeting (Hybrid) on Pandemic Influenza Preparedness (PIP) Partnership Contribution (PC) and WHO’s Preparedness and Resilience for Emerging Threats (PRET) Implementation in SEAR in Colombo, Sri Lanka, 27 to 30 October 2025. Read more18th Bi-regional Meeting (Virtual) of National Influenza Centres (NICs) and influenza surveillance in WHO South-East Asia and Western Pacific Regions from 9 to 11 September 2025. Read morePUBLICATIONSImplications of influenza A virus surveillance in Southeast Asian Region countries: a scoping review of approaches for the surveillance of swine influenza viruses at human-swine interfaces. Read moreAnnual South-East Asia regional meeting on operational planning for implementation of global influenza strategy and preparedness for respiratory viruses in 2025 Report on annual review meeting of implementation of pandemic influenza preparedness (PIP) partnership Contribution (PC) Fund in South-East Asia Region and the simulation exercise on PRET Status of influenza in who south-East Asia Region
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