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Four researchers win data harmonization competition
The U.S. National Science Foundation National Synthesis Center for Emergence in the Molecular and Cellular Sciences (NCEMS) at Penn State has awarded four researchers from across the world for their efforts in a competition to build machine learning-based approaches for streamlining publicly available datasets for reuse.
Buying the Beautiful Game—and Beyond
With the 2026 World Cup approaching, advisor Laurie Pinto breaks down how US private equity and American investors are reshaping European football valuations.
AI Is Forcing Big Law to Rethink Business As Usual
In 2021, Volkswagen AG approached the global law firm Freshfields with a problem. The German carmaker’s technology unit was preparing to release new software features and wanted to make sure that they would be compliant in the more than 100 countries where Volkswagens are sold. Ordinarily, Freshfields said, it would bring in lawyers from each jurisdiction to vet the updates, budgeting thousands of euros per country — a process that would need to be repeated if any components changed in the futur
How the atmosphere at the FA Cup final epitomised the spirit of togetherness in the women’s game
The gate may have been down appreciably on recent years, but the Wembley showpiece was a celebration - particularly for Manchester City
Ministry of Public Health, WHO Thailand and the Embassy of the People’s Republic of China in the Kingdom of Thailand launch initiative to strengthen Thailand’s public health workforce
28 May 2026 | Embassy of the People’s Republic of China in ThailandA skilled and coordinated public health workforce is essential for protecting population health and responding to public health emergencies. Strengthening these capacities was the focus of a meeting held on 28 May 2026 at the Embassy of the People’s Republic of China in Thailand.Dr Ailan Li, WHO Representative to Thailand, together with Dr Watcharanan Tinnaitorn, Deputy Director of the Division of Public Health Emergency Management, Ministry of Public Health, and officials from WHO and the Ministry of Public Health, met with Counselor Zhang Xiaoxiao from the Economic & Commercial Counsellor's Office, Embassy of the People’s Republic of China in the Kingdom of Thailand to mark the launch of collaboration under the WHO Roadmap to strengthen the public health workforce.The initiative supports Thailand in strengthening its public health workforce across both health and non-health sectors. Public health emergencies require coordinated action across a wide range of professions and institutions, including health workers, border control officers, water safety specialists, communication professionals and local government authorities. Through the project, partners will work together to assess workforce capacities, strengthen competencies and promote coordination across sectors to support preparedness and response efforts.The discussion highlighted opportunities to enhance cross-country collaboration through knowledge exchange, communication activities and engagement at key project milestones, supporting workforce development and emergency preparedness efforts.Beyond its immediate objectives, the initiative also reflects Thailand’s contributions to public health at regional and global levels. The exchange highlighted the importance of sharing experiences, lessons learned and good practices through international cooperation to strengthen public health capacity and preparedness.WHO expressed appreciation to the Embassy of the People’s Republic of China in Thailand for supporting the project and recognizing the importance of investing in public health workforce development, preparedness and health security through partnership and multilateral cooperation. WHO also commended Thailand’s continued leadership and commitment to strengthening public health systems and emergency preparedness, including through cross-sector collaboration and workforce development.WHO remains committed to supporting Thailand and partners in advancing resilient and people-centred public health systems and strengthening preparedness for future health challengesAbout the EPHF Roadmap ProjectThailand is one of four countries selected in 2026 to initiate implementation of the Essential Public Health Functions (EPHF) Roadmap, alongside Maldives, Papua New Guinea and Timor-Leste. The initiative is funded by the China International Development Cooperation Agency (CIDCA). The project is led by Thailand’s Ministry of Public Health, with WHO Thailand serving as a co-implementing partner. Other partners include the Chinese Center for Disease Control and Prevention (China CDC), the International Association of National Public Health Institutes (IANPHI), the Global Network for Academic Public Health/Public Health Interprofessional Leadership Alliance (GNAPH/PHILA) and the World Federation of Public Health Associations (WFPHA).
10 Indie Games From 2026 That Feel Like Cult Classics Already
As we approach the midway point of 2026, let's take a look at some under-the-radar indie gems that already feel like cult classic video games.
Burning Question: Are Lions Players Buying Into New Serious Approach?
Examining if Detroit Lions players are sensing a change in the team's approach?
MSI’s New MEG Vision X2 AI+ Desktop Ships With A Talking Holographic Pet That Tweaks Your RGB And Performance On Command
MSI is taking the AI experience to the next level by introducing a live AI agent that helps users in real-time. MSI Unveils MEG Vision X2 AI+ Desktop, Coupled With LuckyClaw That Becomes Personal AI Companion for Making Tasks Easier Artificial Intelligence is no longer limited to chats and image generation. It's now assisting users in real-time, and the new approach just took MSI's newly launched desktop to a new level that might become a common theme in future PCs. MSI has launched MEG Vision X2 AI+, which it calls the "next evolution" in intelligent gaming desktops. Alongside the MEG […]
Who is the most underappreciated player on the 49ers?
A case can be made for Jake Tonges. But is he really the most underappreciated player on the 49ers' roster?
Fever's whole approach is setting Caitlin Clark up to fail
Indiana might want to approach this differently going forward.
A quantum metasurface breakthrough could finally close the terahertz gap
Researchers have developed a compact quantum detector that makes terahertz radiation much easier to detect. A specially designed metasurface funnels incoming energy into tiny active regions, greatly strengthening the electrical signal produced. The approach boosted efficiency by roughly 20 times compared to earlier designs and could pave the way for more practical THz devices in healthcare, communications, and scientific research.
WCADAMHS approves funding for local mental health and addiction services agencies for FY 27
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"They will ruin my life": Microsoft threatens to wield 'Digital Crimes Unit' over zero-day exploit disclosures — causing uproar in the cybersec community
Microsoft's approach to working with security researchers has long been controversial, but some of its recent language has alarmed some commentators.
Utah tightens rules for Kevin O'Leary's AI data center after backlash
Tensions have been high in Utah after a local commission, despite opposition, approved a hyperscale data center campus spanning 40,000 acres.
Iraola the frontrunner with approach made - what do you think?
Outgoing Bournemouth boss Andoni Iraola is the leading contender to replace the sacked Arne Slot at Liverpool. Iraola is one of the most highly rated coaches in Europe and known for his attacking style of play. Bournemouth finished only one place and three points behind Liverpool to qualify for next season's Europa League.
State Airfields Receive Funding
U.S. Senator Cindy Hyde-Smith (R-Miss.), Chair of the Senate Transportation, Housing and Urban Development Appropriations Subcommittee, has reported that 24 municipal airfields in Mississippi have been awarded just over $20 million for facility improvements. The Federal Aviation Administration (FAA) approved the third round of FY2026 Airport Improvement Program grants, which meet Airport Safety and Resilient […]
Watch Remembering the Life and Work of Jonathan Clements: Masters in Business
Barry sits down with Jason Zweig and William Bernstein. They discuss "Money and Me" the last book of author and journalist Jonathan Clements. Jason and William also examine Clements's approach to personal finance and impact to financial journalism.
Pleas and political attacks fill the home stretch of California governor's race
The top candidates for California governor crisscrossed the state Friday, all venturing to friendly political territory to woo voters and undermine their rivals as the June 2 primary election fast approaches.
Jack Campbell vows to epitomize heartbeat of Detroit Lions fans
On the heels of his extension and payday, Jack Campbell made sure to share his appreciation for Detroit Lions fans.
SBA Clarifies And Narrows Its Crackdown On Small Business Investors
The agency had stopped approving loans to businesses with an investor who had previously backed any business that defaulted on an SBA loan. Now it's set up a waiver process.
Tag Team Approaches Helping Earn Wins for Mental Healthcare
By Yanet Luna, Vitals contributor Nearly one in seven California adults experiences a mental health condition. Yet close to two-thirds of those individuals do not receive the needed care, according to a 2022 report by the California Health Care Foundation. Clinical teams, community organizations and mental health advocates across the country understand the importance of creative […]
Approved budget includes $29M for Florida Poly growth and student success
'This investment is a powerful vote of confidence in the role Florida Poly plays in advancing Science, Technology, Engineering, Math, and Medical education.'
Louisiana passes new congressional map to eliminate majority-Black district, give GOP another seat
Approval of the new House map came a month after the U.S. Supreme Court struck down the state’s current map as an illegal racial gerrymander, weakening the landmark 1965 federal Voting Rights Act.
Louisiana Approves Map Eliminating a Majority-Black District
A Supreme Court court ruling last month rejected the state’s previous congressional map as an illegal racial gerrymander and set off a redistricting race across the South.
Questions surround shellfish workforce appropriation tucked into budget
The small appropriation would direct as much as $75K to the FSAA's Executive Director.
What to watch for at the Tony Awards on Broadway’s biggest night
Broadway's biggest night is approaching with the Tony Awards broadcast live from Radio City Music Hall on June 7.
Board approves seven new faculty appointments
The Princeton University Board of Trustees has approved the appointment of seven faculty members, including one full professor and six assistant professors.
Jameela Jamil called out the rise of 'scarily thin' celebs. Let’s talk about it
As we see more celebrities shrinking on red carpets, conversations are surging online. But can we talk about it appropriately? Experts share advice.
Cultivating Data-Driven Approaches with Plant Science
Launched this winter, the Data-Driven Plant Science course bridges experimental biology with embedded sensing, bioinformatics, and machine learning.
WHO Global Code of Practice on the International Recruitment of Health Personnel amended
WHO Member States adopted a resolution to amend the ‘WHO Global Code of Practice on the International Recruitment of Health Personnel’ (the Code) and strengthen its implementation, following Member State-led consultations in the lead up to the Seventy-ninth World Health Assembly. The resolution marks an important step towards the vision that everyone, everywhere can access competent and motivated health and care workers, as a foundation for both universal health coverage and global health security. Key additions to the Code focus on: inclusion of provisions on health personnel recruited internationally for employment as care workers; applicability of the Code recommendations during emergencies; and encouraging co-investment in health systems and health workforce to ensure international recruitment results in proportional benefits for source and destination countries.Since its adoption by the Sixty-third World Health Assembly in 2010, the Code has undergone three rounds of review of its relevance and effectiveness. “We welcome the resolution’s focus on sustainable and ethical mobility of health personnel,” explained Dr Yukiko Nakatani, WHO Assistant Director-General, Health Systems, Access and Data. “The Code’s adoption in 2010 was a landmark achievement. Following this update, we encourage all countries to enhance implementation, including by viewing co-investment as a win-win.” The additions were recommended by an Expert Advisory Group appointed by the WHO Director-General. The Expert Advisory Group’s final report noted the progress in health workforce data availability, provision of migrant health worker rights and the embedding of ethical recruitment principles in national policies. It also highlighted areas of possible improvement in the Code implementation, including support for the strengthening of health systems in source countries.The adoption of the resolution follows extensive consultations led by Member States, underscoring the continued relevance of the Code in a context of increasing international mobility of health workers and growing pressure on health systems resulting from global health emergencies and funding constraints.WHO is already taking forward actions called for in the resolution. An updated version of the ‘WHO health workforce support and safeguards list’, that guides ethical recruitment practices by identifying countries facing the most pressing health workforce challenges, will be published later in 2026. As recommended by the Expert Advisory Group, this will include additional flexibility enabling countries to indicate their willingness to allow active international recruitment, or for Member States not on the list to request tailored support and safeguards. This approach reflects a more nuanced, country-led framework that balances workforce mobility with the need to protect and strengthen health systems in vulnerable settings.“I thank the members of the Expert Advisory Group, the group of Member States who led the resolution, and all Member States for their constructive engagement,” added Dr Nakatani. “Let’s bring this spirit of collaboration to our collective efforts to implement the resolution, strengthen the health workforce and build resilient and equitable health systems.”
Fertitta Entertainment Agrees to Acquire Caesars Entertainment in $17.6B Deal
HOUSTON, LAS VEGAS AND RENO, NEV. — Fertitta Entertainment Inc., a private holding company controlled by the NBA’s Houston Rockets governor (i.e. owner) Tilman Fertitta, has entered into a definitive agreement to acquire casino and gaming giant Caesars Entertainment (NASDAQ: CZR) for $17.6 billion. Fertitta Entertainment plans to finance the acquisition through a combination of equity, assumed Caesars’ outstanding debt (approximately $11.9 billion) and new committed debt financing arranged by a consortium of 10 banks. Under terms of the agreement, Caesars shareholders will receive $31 in cash for each outstanding share, which represents a 49 percent premium to the company’s unaffected stock price on Feb. 25 (the last trading day before rumors of a potential transaction were reported) — $20.77 per share. Upon completion of the transaction, shares of Caesars Entertainment common stock will no longer be listed on the NASDAQ stock exchange. Caesars operates several major Las Vegas Strip properties, such as Caesars Palace, Harrah’s, Paris Las Vegas, Planet Hollywood, Horseshoe, The LINQ Hotel, Flamingo and The Cromwell. Fertitta Entertainment owns Golden Nugget Hotels & Casinos and operates more than 450 full-service restaurants around the world, including Landry’s, Rainforest Café and Morton’s. According to the press releases issued by both companies,…
Google won the search war. It's using the same tactic to win in AI.
Inference costs are becoming a race to the bottom, and Google's full stack AI approach puts it in a good position to offer cheaper tokens.
IFF Enters Into Agreement to Sell Its Food Ingredients Business to CVC
IFF (NYSE: IFF), a global leader in flavors, fragrances, food ingredients, and health and biosciences, today announced that it has entered into an agreement to sell its Food Ingredients business to funds advised by CVC Capital Partners, a leading global private markets manager, in a transaction that values the business at approximately $4.3 billion, representing an enterprise value-to-EBITDA multiple of approximately 10x.
Trump’s Iran Approach Sows Confusion
President Trump’s pendulum swings on Iran have often seemed driven by mood and moment rather than any discernible strategy.
A Democrat’s Dodge on AIPAC Points to the Party’s Tensions Over Israel
A key moment at a Senate primary debate in Michigan showed how pro-Israel Democrats are approaching the issue with caution.
Bessent: Nothing 'untoward' about Trump appearing on $250 bill
The treasury secretary said his department has been preparing in case Congress approves legislation creating the $250 bills
Fireweed pitch: Unwinnable Democrats should back GOP, independents
If Democrats cannot win the 1st U.S. Congressional District race in Montana, the party is better positioned backing select moderate Republicans or independent candidates who can advance at least some of the agenda. That’s what Fireweed Campaigns, a self-described politically independent Helena-based firm with only Republican clients pitched to a room of approximately a dozen ‘Democrat-adjacent’ strategists mixed with representatives during a quiet strategy meeting in Anaconda in the summer of 2025.
The U.S. Is Proving the Case for the WHO
By responding to the Ebola outbreak independently, the U.S. is showing the limits of that approach.
Caesars Entertainment Agrees to Be Acquired by Fertitta Entertainment
Caesars Entertainment, Inc. has entered into a definitive agreement to be acquired by Fertitta Entertainment, Inc. in an all-cash transaction valued at approximately $17.6 billion, including the assumption of approximately $11.9 billion of Caesars’ outstanding debt.
'Business-Like' Approach Has Canes One Win Shy Of Stanley Cup Final
"I don’t think we’re an overconfident group. I think we’re a confident group in what we do, and we respect every minute of the playoffs."
Renault Group’s climate ambition based on science
Press ReleaseMay 28, 2026 Renault Group’s climate ambition based on science In 2019, Renault Group was the first carmaker to rely on science-based climate targets.Renault Group is announcing the renewal of its science-based targets, with a new approval of its near- and long-term targets by the Science Based Targets initiative. These targets are supported by the product momentum of futuREady strategic plan. Boulogne-Billancourt, May 28, 2026 In 2019, Renault Group was the first carmaker to rely o
Michigan Launches New Online Form to Improve Reporting, Tracking of Harmful Algal Blooms
From the Michigan Department of Health and Human ServicesLANSING, Michigan – As summer approaches, the Michigan Departments of Environment, Great Lakes, and Energy (EGLE), Health and Human Servi
How Large Businesses Can Manage Energy Risks and Price Volatility
Unpredictable energy market conditions are raising risks for large businesses. Explore how a managed approach supports long-term resilience.
Caesars Entertainment to be acquired for $17.6B
Caesars Entertainment has entered into a definitive agreement to be acquired by Fertitta Entertainment in an all-cash transaction valued at approximately $17.6 billion, including the assumption of | Fertitta Entertainment will acquire Caesars Entertainment in an all-cash transaction.
ExxonMobil shareholders approve moving company’s legal home from New Jersey to Texas
ExxonMobil’s board of directors said the legal and regulatory environment in Texas is more business friendly.
News | Texas billionaire to acquire Caesars Entertainment in $5.7 billion deal
Fertitta Entertainment has already received board approval
Medicaid’s Vital Role in Mental Health and Substance Use Disorder Care
Mental Health Awareness Month is an opportunity to recognize Medicaid’s essential role in helping people access mental health care and treatment for substance use disorder. As the nation’s largest payer for mental health and substance use disorder care, Medicaid covers approximately twenty two million non-elderly Americans with these conditions who rely on the program’s essential […]
FIFA's World Cup Ticket Strategy Is Extreme Version of Wider Approach
FIFA's World Cup ticket strategy has drawn criticism. It's a more extreme version of a profit-maximization approach that is becoming common in sports.
Fertitta Entertainment: $17.6 Billion Caesars Entertainment Acquisition Deal Announced
Fertitta Entertainment announced a definitive agreement to acquire Caesars Entertainment in an all-cash transaction valued at approximately $17.6 billion, including the assumption of about $11.9 billion in Caesars’ outstanding debt.
Trump won big with the White working-class. Now they’re souring on him.
In a striking shift, White voters without college degrees that voted to reelect Trump by a huge margin are now net-negative on his job approval.
Weeks in Review: Spring Sports Wrap-Up
With deadweek and finals quickly approaching, the end of the 2025-26 academic year also marks the end of all seasons for Seattle University Athletics. For the final “Week in Review” of the year, let’s take a look at how the teams that competed in the spring season finished their West Coast Conference (WCC) debut. Softball ...
Indiana regulators OK Texas company's purchase of Indiana power plant
The $3.45 billion transaction, which includes two other power plants, still requires federal approval and faces a challenge related to market competition concerns.
J.J. McCarthy Uses ‘Classroom’ Analogy to Describe Relationship With Kyler Murray
In his first public comments since Murray signed with the eager-to-contend Vikings, McCarthy sounded as though he understood the situation but did not necessarily appreciate it.
New depression treatment targets the immune system instead of the brain
A surprising new approach to depression treatment is showing early promise — not by targeting brain chemicals, but by calming the immune system. In a small clinical trial, researchers found that an anti-inflammatory drug normally used for rheumatoid arthritis appeared to ease symptoms in people with hard-to-treat depression, while also reducing fatigue and anxiety and improving quality of life.
31 hours with the spit-shined Mina the Hollower (and 34 with the four games that came before it)
To truly appreciate Mina The Hollower, an extraordinary new throwback of a game, I sent myself to Yacht Club University. That’s not a real institution of higher learning, but it’s the best way I can explain much of the past several weeks as I prepared to play Mina by playing the four biggest game previously made by studio Yacht Club Games. I had expected Mina the Hollower, in development for six years for PC and consoles, to potentially be something special. A demo I tried in March had felt great. Mina the Hollower had an old-school premise: a singular move for its hero that felt so good to control and so rich with possibilities that, in the hands of skilled designers, it could be riffed on in various ways for the length of a full game. Mina’s core maneuver, her hollowing, made her sort of an upside down Super Mario. Nintendo’s hero jumps through the air, discovering power-ups at the apex of his jump by bonking overhead blocks, then defeating enemies by landing on them. Mina essentially jumps into the ground, digging (“hollowing”) into the earth to fetch buried treasure, then burrows for a short distance to emerge on the other side of a wall that hides treasure or an enemy that needs some battering. I wanted to understand how good Yacht Club was at making games. I wanted to see how far they’d come. If Mina was terrific—as I predicted it might be—I wanted to feel how they got there, one button press at a time. On May 6, 21 days before the writing of this review, I checked with Yacht Club Games co-founder and programmer David D’Angelo, to ask which of the studio’s games I should play to truly appreciate the new one’s design. “Hmmm all of them?” he wrote back. “Starting with Shovel Knight definitely is helpful,” he continued, referring to Yacht Club’s first game. He gave me a link to a spreadsheet of over 400 cheat codes that could help me out, if I found the game too tough.1 “Most folks say Specter of Torment is the least difficult and quickest to finish in terms of playtime, and [it] refines much of Shovel Knight,” he told me. “King of Cards is a big celebration of everything we did in [the Shovel Knight compilation] Treasure Trove— might work for you better if you’re a fan of shorter, Mario-style courses. And it’s probably the closest to Mina in terms of polish.” So that was that. Four games, none of which were required. Mina is a whole new game in a whole new world, best I can tell. I’d barely played that first Shovel Knight before and never the other three. I just thought it’d help. It did. It turns out that playing a game studios major works before their latest is very illuminating.
Uganda closes its border with Congo, where suspected cases of rare Ebola type are surging
The measure, which goes against the guidance by the World Health Organization, underscores growing fears of contagion in East Africa from Bundibugyo, a rare type of the Ebola virus that is behind this outbreak and that has no approved medicines or vaccines.
Talarico makes stunning claim about why he thinks Texas elections aren't fully 'free and fair'
Texas Senate candidate James Talarico is claming state election laws amount to voter suppression, vowing to out-organize GOP rival Ken Paxton in 2026.
Colorado Gov. Polis signs RTD overhaul bill aimed at rebuilding transit ridership
Gov. Jared Polis on Tuesday approved a sweeping overhaul of the Regional Transportation District, signing a bill that reshapes the agency’s leadership and seeks to reverse years of stagnant ridership and eroding public trust in metro Denver’s transit system. Senate Bill 150 — sponsored by Sens. Iman Jodeh of Aurora and Matt Ball of Denver, […]
Jalen Hurts details philosophical shift in Eagles offense
Jalen Hurts said Sean Mannion's offense brings a different philosophical approach as the Eagles continue installing a revamped system during OTAs.
La Union uses Business Community Ownership Fund to build community with their commercial space
As interior designers, Sonia-Lynn Abenojar and Sergio Max Legon-Talmoni know what it takes to turn an idea into a reality. “Our role as designers is taking the big idea from the client, any inspiration they have from aesthetics to function, and putting them into drawing form so the City can review and approve it. Then […]
Midterm redistricting has placed millions in new voting districts. Here's where 6 state efforts stand
President Donald Trump hopes the unusual mid-decade redistricting can help Republicans retain control of the closely divided House, despite negative approval ratings and historical tendencies for the incumbent's party to lose seats
Sports Minister: ‘Not appropriate’ for Italy to take World Cup spot
Italy’s Minister for Sport, Andrea Abodi, asserts that it is neither ‘possible’ nor ‘appropriate’ for the Azzurri to be considered for admission to the World Cup as a replacement for Iran.It...
Eagle approves live entertainment permit for Woodstone at the Flats
Owners say the former Flats 16 property will become a community gathering space with restaurants, events, pop-up shops and outdoor areas
Cosmonauts Prep for Spacewalk for Science Work Today on NASA+
Live coverage is underway as two Roscosmos cosmonauts prepare for a spacewalk outside the International Space Station. The spacewalk is scheduled to begin at approximately 10:15 a.m. EDT and last roughly five hours.
Rob McElhenney talks 'football,' giving World Cup fans chance to win free car
Rob McElhenney dishes on soccer, how the cultures of Wrexham and Necaxa have shaped his growth and appreciation for the sport ahead of the World Cup.
The Art and Science of Transforming California’s Forests
As California’s wildfire season approaches, how is the state working to prevent severe wildfires? We convened a panel of experts to discuss our new report on the state’s progress—and to look at what can help the effort stay on track.
Palm Coast Welcomes the Big Buoys to Indian Trails Sports Complex
At the May 20, 2026, City Council Business Meeting, the Palm Coast City Council approved a Facility Use Agreement with Palm Coast Baseball LLC, allowing Baseball Field #2 at the Indian Trails Sports Complex to host collegiate baseball games as part of the newly established Orange State League.
Ebola, chemical plants and health, hantavirus, common colds, heat and more
As they say, bugs have ears. Public health has had a relentless May. Chemical plant (near) explosions, Ebola, hantavirus, and that's before you even get to the usual suspects: common colds, heat, and ticks. Here’s an attempt to keep you up to speed and, more importantly, what it means for you and your community. But first, an announcement: World Cup The World Cup starts in 15 days (not like anyone is counting down), and we are hanging TVs in the Health Security Operations Center. It’s going to be a gorgeous, chaotic celebration of basically every culture on earth. And it’s going to take a team effort—from communities to individuals, from public health to health care—to keep people healthy. That’s where you come in. If you’re going to the games or live within 30 miles of a stadium, we would love to hear from you. Sign up for a weekly survey here. Thanks to the more than 1,280 people who have already signed up…you will be hearing from us soon!! Global disease “weather report” Hantavirus: Two more cases The global count of cruise ship passengers with hantavirus has now increased to 13 cases (11 confirmed), with three deaths. The two new cases are overseas and among people who were already quarantining: A crew member in the Netherlands. A Spanish national passenger who was quarantining at home tested positive through daily monitoring. They are now in a biocontainment unit. In the U.S., everyone remains negative. There may be more cases, given that the incubation period of hantavirus (the time from exposure to infection) is 45 days. But this week, we will reach a major milestone: the median incubation window is 18 days, and that will pass on May 29. What this means for you: Your risk from this cruise ship outbreak remains essentially nil at this point. Ebola rages on in Central Africa Big thanks to Dr. Craig Spencer, a humanitarian physician who has treated and survived Ebola, for jumping in to provide the YLE community with an update. Craig, take it from here… The combined confirmed and suspected Ebola cases in DRC are now more than 1,000. All signs are pointing to a very long and catastrophic outbreak in Central Africa: This is a vast undercount. We know this because the test positivity rate is hovering around 50%, only 20% of contacts are being traced (and in some areas, no contacts at all), and more cases keep popping up with no known connection. This all points to widespread and undetected community transmission. This is in only a week of detection. Compared to previous outbreaks, the growth is very fast, as the huge West Africa outbreak in 2016 was first detected at 49 cases and rose to 208 cases a month later. It took four months for that outbreak to reach the size of the current one in the DR Congo. The cases are spread out across 16 health zones. There are now multiple epicenters, making containment very difficult. Next door in Uganda, the case count is seven. While this number is low compared to DRC, a concerning development is that two health care workers recently tested positive with uncertain exposure histories. If they weren’t treating known Ebola cases, this means it’s spreading undetected in Uganda as well. On the ground, backlash, including the burning of health centers, has emerged, a pattern seen in nearly every outbreak and rooted in deep community distrust. It often stems from outside actors working in communities without fully understanding or addressing local priorities. Affected populations may recognize the severity of Ebola while still holding other concerns as more pressing, such as where their loved ones are buried. Community trust is essential to an effective response, but difficult to build during an active emergency. It is best established long before a crisis begins. U.S. priorities are made clear, and may backfire. The U.S. Administration has shown that its first priority is keeping Ebola out, with helping end the outbreak in the DRC a secondary concern. That's meant travel restrictions broader than anything we've imposed before — covering travelers from across the region, and reportedly some green card holders and permanent residents as well. For example, just these past two days, news broke that high-risk American travelers will be subject to a mandatory quarantine in Kenya before they are allowed to return. If an American is infected, the U.S. government plans to send them to a hospital it is standing up from scratch in Kenya. (Currently, Americans who were in the area are allowed to return but are diverted to three airports—Houston, Atlanta, and DC—for further screening.) Past administrations have used travel notices and stepped-up screening; this goes much further. At first blush, these strict precautions may sound prudent. But this approach could backfire in three ways: Restrictions this blunt give people every reason to hide where they’ve been and whom they’ve been near — making the people we most need to find harder to track, not easier. They also breed a false sense that this is someone else’s problem. But diseases are humbling. They find the small cracks in even the most impenetrable-seeming defenses. Lives lost. There is no treatment for this Ebola strain, which means survival depends heavily on the quality of the health system. We have that system in the States, but we are choosing not to use it for infected Americans. This is unbelievable and infuriating. (See a deeper dive from me here.) The only real way to lower the risk to Americans — and everyone else — is to end the outbreak in the DRC and across the region. What this means for you: If you have travel plans to this region, it’s time to cancel them. This is a high-risk situation in Central Africa, and CDC released a Level 4 Travel Advisory. There is also great uncertainty if and when the Administration will let you back in. To the general public in the U.S., your risk remains very, very low right now. U.S. disease “weather report” Ticks: past peak season? Good news, especially for people in the Northeast and Midwest: tick numbers continue to decline. Though we are at the peak of the season, this unusually early year is trending favorably. Heat-related illnesses in the North Heat risk is certainly not blanketing the entire country yet, but this week it will be moderate in the Midwest and the Southeast. What this means for you: Be sure to check the CDC HeatRisk tool. A red day isn’t the best day for that soccer game for a kid with asthma, and a stretch of orange days is a great time to check on your elderly neighbor. Common colds surging As far as respiratory viruses go, the only thing really going around right now is the common cold. It is higher this year than last year, but should peak very soon before returning this fall. Spotlight: Chemical plants Over the weekend, YLE California covered the serious situation that unfolded around a chemical plant in Orange County, California. Thankfully, the worst-case scenario (a chemical explosion) was mitigated, but only through luck. The health implications in a densely populated area could have been catastrophic. As the situation was winding down, another chemical explosion struck Washington State. This one was fatal. Health officials say the risk to surrounding residents from chemicals in the air and ground remains low, though the community deserves far greater clarity. Clean air and clean water consistently rank as Americans’ top public health concerns — yet when chemical disasters strike, communities are too often met with reassurances rather than transparency and accountability. Residents near the 2023 East Palestine, Ohio train derailment, for example, are still waiting to understand the long-term impact on their health, with few clear answers. What this means for you: Many are wondering if facilities processing potentially dangerous materials are in their neighborhoods. This interactive map allows you to enter your ZIP code and see all facilities monitored by the EPA, including any violations. Good news Ebola vaccines and treatment for the Bundibugyo species are in development. Two vaccine platforms are being explored, at least one of which may be deployable in as little as 2 months. One vaccine is being developed by Oxford, and the other uses the same biotechnology as the FDA-approved Zaire species of Ebola. (It may provide cross-protection, but it’s unclear at this point.) On the treatment side, two promising monoclonal antibody cocktails are likely to be deployed, though doses are limited and logistical hurdles remain significant challenges. Anni over at The Biotech Tea had a great explainer about the Ebola vaccine gap, if you want to read more. [ The Biotech Tea The Ebola vaccine gap, reading vessel damage, & the Makary exit 🗝️ Paid subscribers get the Biotech Term of the Week at $30/year (~$2.50/month). I try to keep it intentionally accessible, but if cost is ever a barrier, send me a message. A few people asked about expensing your subscription, so I put together a short email template… Read more 6 days ago · 10 likes · Annicka Evans, PhD ](https://www.thebiotechtea.com/p/the-ebola-vaccine-gap-reading-vessel?utm_source=substack&utm_campaign=post_embed&utm_medium=web) Polycystic ovary syndrome (PCOS) has been officially renamed polyendocrine metabolic ovarian syndrome (PMOS), following more than a decade of debate and input from roughly 22,000 clinicians, researchers, and patients worldwide. This is good because the old name was medically misleading, leading to patients without visible cysts being dismissed or overlooked entirely. The WHO estimates that 70% of people with the condition remain undiagnosed. A more accurate name should improve recognition, reduce stigma, and ultimately help the millions of people living with this condition get diagnosed and treated sooner. Poll Loading... Bottom line Public health situations are everywhere right now. Staying healthy takes public health professionals and systems working tirelessly behind the scenes and each of us showing up for our neighbors and communities. Love, YLE Big thanks to Ed Nirenberg for staying on top of the Ebola vaccines, Hannah Totte for all the figures, Dr. Craig Spencer for the Ebola insight, and Dr. Matt Willis for covering the chemical situation in CA. Your Local Epidemiologist (YLE) comprises a team of experts, ranging from physicians to immunologists to epidemiologists to nutritionists, working together with one goal: to “Translate” ever-evolving public health science so that people are well-equipped to make evidence-based decisions. YLE suite of newsletters reaches over 475,000 people across more than 132 countries. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe
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Effective preparedness for high-threat pathogens demands more than technical tools — it requires a coherent strategy, sustained country engagement, and the institutional infrastructure to translate evidence into action. In 2025, the Pandemic and Epidemic Management (PEM) Unit advanced all three, working across the full spectrum of high threat pathogen (HTP) preparedness: from methodology development and evidence generation to country-level technical support, emergency response, and regional workforce strengthening.At the core of the PEM unit's work is building the regional evidence and policy architecture needed to prioritize and respond to HTPs systematically. A major milestone was the development of the HTP Prioritization Methodology — a structured, multi-criteria approach to ranking pathogens by epidemic potential, severity, and national context — and its national pilot in Bangladesh, where SARS-CoV-2, Nipah, dengue, and cholera emerged as the highest-priority threats, informing the PEM unit's contribution to 2026–27 biennium prioritization and workplan development (Access link here).Underpinning this work, the PEM unit advanced the peer-reviewed evidence base for HTP preparedness in the South-East Asia Region (SEAR), with three publications in international journals in 2025: Development of a zoonotic influenza distribution assessment and ranking system (ZIDAR): Technical application in Nepal to support cross-sectoral risk-based surveillance in One Health; Implications for influenza A virus surveillance in Southeast Asian Region countries: a scoping review of approaches for the surveillance of swine influenza viruses at human-swine interfaces in BMJ Public Health; and Operationalizing multisector partnerships: a Theory of Action and Reflection tool for zoonotic influenzas in Health Policy and Planning. Together, these contributions move the Region’s HTP preparedness agenda from practice to science — generating the transferable methodological foundations that will inform evidence-based capacity strengthening in Member States.Country-level engagement in 2025 reflected the breadth of contexts in which HTP preparedness must function. Technical support was provided for Mpox and cholera events across the Region, including coordination of cholera and acute watery diarrhea prevention and control in Myanmar in the wake of the March 2025 earthquake. In Myanmar, the PEM unit contributed technical leadership to the earthquake emergency response — one of the most complex humanitarian emergencies in the SEAR — as Health Operations and Technical Support lead within the Incident Management Support Team. This included strengthening emergency response planning, supporting operational and after-action reviews, and providing monitoring and evaluation support for both acute and protracted crisis response. The breadth of HTP support provided to emergency operations across the SEAR was documented in the PEM unit’s contribution to the regional report for the Health Security Interface Technical Advisory Group.In Sri Lanka, technical collaboration with the WHO Country Office and the Ministry of Health laid the groundwork for the National Steering Committee's 2026 annual meeting, development of Standard Operating Procedures for specialized emergency response, and a national training programme — all structured around evidence-based risk assessment for specialized hazards including HTPs.Across the SEAR, the unit contributed to strengthening the workforce architecture that underpins HTP response. Technical inputs shaped the WHO South-East Asia Regional Health Emergency Workforce Strategy 2025–2030, and the PEM unit supported conceptual development of the health emergency workforce framework for the Pandemic Fund Round 3 proposal.Alongside this, the unit's sustained engagement on the meningitis agenda culminated in the launch of the Regional Implementation Framework to Defeat Meningitis in South-East Asia by 2030 at the Seventy-eighth Session of the Regional Committee, ensuring the Region's priorities were reflected in the Global Technical Task Force and expanding the unit's HTP engagement beyond outbreak-prone zoonotic pathogens (Regional Implementation Framework to Defeat Meningitis in South-East Asia by 2030).Taken together, 2025 demonstrated that meaningful HTP preparedness is built incrementally — through methodology, engagement, and the steady accumulation of institutional capacity across Member States.Bangladesh piloted the HTP Prioritization Methodology and identified the highest-priority pathogens in the country context (Photo credit: WHO Country Office, Bangladesh).
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