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Ancient cave paintings can harbor human DNA for millennia, scientists find
The breakthrough could reveal previously hidden ancient human activity inside caves, acting as ‘genetic archives’
‘The science is here’: UN chief welcomes first global AI assessment
Fresh scientific evidence and options for harnessing artificial intelligence (AI) were unveiled Wednesday following the launch of the first global, independent scientific assessment of opportunities, risks and impacts by a pioneering UN expert panel.
If we lose our coverage, we lose our lives
By Thomas Buckley My oncologist asked: “Polycythemia Vera. Do you know what that means?” Earlier, I lived in blissful ignorance, unaware I potentially carried a myeloproliferative neoplasm encoded within my DNA. “Yes,” I answered, “A rare form of blood cancer, incurable, not necessarily fatal, provided it’s treated.” At 31, I thought I had life figured […]
‘Beautiful blobs’: synthetic life a step closer as scientists make cells using lab-made DNA
Tiny, quivering spheres designed to feed and multiply raise prospect of artificial organisms to make drugs, food and fuel
FBI reportedly deems three ransom notes tied to Nancy Guthrie disappearance to be fake
The FBI reportedly denies the veracity of three ransom notes linked to the disappearance of Nancy Guthrie: two from February, sent days after she was declared missing, and one from June, alleging to have video of her following her kidnapping.
Venezuela quake: key services crippled and health workers missing
Search and rescue operations continued in Venezuela on Tuesday as thousands of displaced people struggled to find shelter and humanitarians warned about the spread of infectious disease.
Terrion Arnold released: Where Lions go from here after secondary suffers loss, plus potential replacements
The Lions cut ties with their former first-round pick after his arrest on kidnapping and armed robbery charges, leaving a void in Detroit's secondary.
Nancy Guthrie demand letter’s authenticity questioned by sheriff
Pima County Sheriff Chris Nanos weighs in on a new demand letter in the Nancy Guthrie case, which claims to know who kidnapped the mother of 'Today' host Savannah Guthrie.
Scientists Found Ancient Human DNA on Cave Walls for the First Time and It Could Rewrite the Story of Prehistoric Art
The find could transform how researchers study prehistoric cave art.
Lakers Have Reportedly Not Offered LeBron James a Contract Yet
With free agency set to officially open on June 30, the Los Angeles Lakers still have not put a contract offer in front of their 41-year-old star.
New Nancy Guthrie demand letter claims to have video from her 'last' day: Report
A new demand letter about Nancy Guthrie reportedly claims to have video of the 84-year-old and her kidnapper on 'the day that was probably her last.'
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Europe heatwave breaks records as UN agencies ramp up health warnings
As a record-breaking heatwave grips large parts of Europe, the World Meteorological Organization (WMO), national weather services and partners are mobilising heat-health action plans for millions of people facing dangerous temperatures.
Former MLB GM Shares Answer To Yankees' Bullpen Woes
The New York Yankees have a clear need in the bullpen, but the team may not have to acquire one through a trade. New York addressed its bullpen at last year's trade deadline, acquiring the likes of David Bednar and Camilo Doval among other relievers. However, Doval has struggled this season, so the ...
Scientists identify New Walking Shark Species With Morse Code-like Markings
A shark long known to Papua New Guinea communities has finally been confirmed by DNA as a species new to science.
New DNA study of Neanderthals bolsters suspicions of human-driven extinction
Analysis of 27 genomes reveals more diverse, better-connected populations and challenges the idea that genetic decline caused their disappearance
Preview: Star Wars: Galactic Racer's physics-based destructive tech and high-speed DNA shows promise
Now this is podracing!
Hidden bird species discovered in Japan after DNA reveals a stunning secret
A bird long thought to be a single rare species in Japan has turned out to be two. Scientists discovered that the elusive Ijima’s Leaf Warbler and a newly identified Tokara Leaf Warbler look almost identical, but their DNA and songs reveal they are distinct species. The finding marks Japan’s first new bird species discovery in more than 40 years and highlights how modern genetic tools are uncovering hidden biodiversity that would otherwise go unnoticed.
Chicago Bears Will Have 2 Joint Practices This Preseason
The Bears will have another joint practice this summer, as it was just announced that they’ll work out with the Titans. @wiltfongjr has the details here:
Accidentally Leaked FSR 4.1.1 INT8 Reportedly Works With RDNA 3.5 Graphics
Valve's leak reveals FSR 4.1.1 INT8 supports RDNA 3.5 and RDNA 2 GPUs, with successful tests on RX 7800 XT and RX 6900 XT
Valve leaks FSR 4.1 for RDNA 3 and RDNA 3.5 GPUs through Proton Experimental
FSR 4.1 file works with RDNA 3 and RDNA 3.5 GPUs Valve appears to have pushed an early FSR 4.1 build through Proton Experimental.
AMD has reportedly released FSR 4 for RDNA3 GPUs in Valve Proton Experimental
AMD FSR4 appears to be coming to Valve’s Proton Experimental.
Scientists discover neurons must break their DNA to build the brain
As newborn neurons make their way through the developing brain, they must squeeze through incredibly tight spaces to reach their final destinations. Researchers discovered that this physical journey routinely causes some of the most severe forms of DNA damage—double-strand breaks—yet the young brain has evolved an impressive ability to repair the damage almost immediately.
This DNA repair gene went rogue and exposed a cancer weakness
Scientists have discovered that a gene normally considered a DNA-protecting "good guy" can become dangerous when cells make too much of it. The gene, EXO1, acts like molecular scissors that help repair DNA, but when overproduced it starts cutting DNA it shouldn't, creating damage linked to cancer.
DNA’s Made in Elgin Shop plans to open downtown in July
The Made In Elgin Shop, part of DNA’s Made In Elgin Incubator Program, is to open downtown selling items made by 8 entrepreneurs.
DNA time stamps reveal the strawberry’s surprising origins
Researchers have created a new way to reconstruct the evolutionary history of complex plant genomes by analyzing genetic traces left by transposable elements. The technique revealed that modern strawberries were assembled through multiple ancient genome-merging events, shedding new light on how major crop species evolved.
"Lost Civilizations" Linked by DNA: What Scientists Just Uncovered Changes Everything - Futura-Sciences
Megalithic Mysteries: A Shared Heritage Revealed At the closing of the Neolithic era, roughly between 4500 and 2800 BCE, vast megalithic monuments began to rise across Europe. These massive stone structures, often used as collective burial chambers, are a testament not only to strong local traditions but also hint at...
Scientists solve millipede mystery, and find they beat vertebrates onto land by 80 million years
"It took 10 people over a week just to find this one tiny 10-millimeter adult."
A Nashville business graveyard: How 12 South has priced out local owners
Burger Up will join Mafioza’s, Josephine’s, 12 South Taproom and so many others on the list of shuttered businesses in the area.
Scientists Reveal Why Mosquitoes Bite Some People More Than Others
"It's not a misconception."
Merchants of Doubt and the attacks on Extreme Event Attribution science
Last week, I attended a meeting at Columbia University on attribution science and climate law, hosted by the Sabin Center. It was a fantastic event, bringing together scientists and legal experts working at the intersection of extreme event attribution and climate law. Subscribe For those unfamiliar with it, extreme event attribution attempts to quantify the contribution of climate change to an extreme event. For example, several groups analyzed the impact of climate change on Hurricane Harvey’s enormous rainfall totals over Houston, Texas and they found that climate change increased rainfall by 15 to 38%. One thing that came up again and again was how terrified fossil-fuel interests are of extreme event attribution science. They are acutely aware that this research could land them in court. And losing those cases would leave them legally liable for billions of dollars in climate damages. Because the legal stakes are so high, the blowback has turned ugly. I spoke with several scientists at the meeting who are facing ongoing harassment over their work. This blowback is a coordinated campaign to make the entire field look suspect. The goal is to create the impression that attribution science is too uncertain, too political, or too conflicted to be useful in court or in public policy. The strategy is not based on actual science or evidence of misconduct, but on the generation of doubt. The new Merchants of Doubt We’ve seen this before. In fact, not that long ago: We only have to go back a year to the Department of Energy (DOE) Climate Working Group (CWG) report to see an example of using doubt as the tool to push back against well-established science. This strategy is laid out in an email from a member of the CWG, Dr. Roy Spencer, that was released during litigation over the Climate Working Group process. The key quote is: About all I can hope is that what we write will provide sufficient “reasonable scientific doubt” regarding the science claims in the 2009 TSD [technical support document], based upon almost 2 decades of new science, to call into question the original reasoning for the EPA Administrator’s decision that CO2 presents a threat to human health and welfare. This statement is strong evidence that at least some members of the committee were working to support a particular policy outcome: revoking the Endangerment Finding. The email also explains how they planned to do it: by attempting to generate “reasonable doubt”. This is going to be hard, Spencer implies. Despite falsely claiming that “2 decades of new science” weakens the case, Spencer explicitly acknowledges that the actual peer-reviewed science of climate change overwhelmingly rejects his position: But if the science argument is decided upon by a vote, or by the number of published citations, we lose the science argument. We can go back even further: This CWG email shares unmistakable DNA with the infamous 1969 tobacco memo that declared: “Doubt is our product, since it is the best means of competing with the ‘body of fact’ that exists in the mind of the general public. It is also the means of establishing a controversy.” The tobacco memo also acknowledges the limit of this strategy: Like the CWG, they knew the science was not on their side. Share The new new Merchants of Doubt The people attacking the IPCC chapter on extreme event attribution are the newest iteration of the Merchants of Doubt. Their goal, like all Merchants before them, is to introduce doubt into the process. Because the report is not even out yet, they cannot attack its conclusions. So they are attacking the authors instead. Here is a press release from the House Science, Space, and Technology Committee: In the letter, the Chairmen express concerns about potential conflicts of interest involving members of the Attribution Committee, stating that “publicly available information suggests a troubling pattern” in which committee members are affiliated with nonprofits that support climate accountability lawsuits, “raising the appearance of impropriety and member bias.” To be clear, this is just innuendo. There is no actual evidence of bias. And given the robust process that these reports go through, including multiple lines of peer review, it seems very unlikely that significant bias can survive into the report. When the report comes out, critics will have the opportunity to make legitimate criticisms of the report — if any exist. If none do, however, they’ll still make criticisms, but they’ll be bogus, simply designed to generate doubt. We’ll see. A note to the press: Fix your frame To any journalists reading this: The public debate over extreme event attribution science is not going away. The science is simply too dangerous to fossil-fuel interests for them to stop fighting it. You very well might be assigned to write an article about this area of research in the future. When you do, do not automatically adopt the framing that climate misinformers want you to use. They want you to frame the story around questions like: Are climate scientists trying to put their thumb on the scale to achieve a predetermined, politically motivated result? Are climate scientists improperly letting their politics invade the science of the IPCC? That frame is a trap. Instead, you need to view this through the historical lens of the Merchants of Doubt. How does the ecosystem of doubt operate? Who funds it? What methods do they use to misrepresent science and slime researchers? What scientific results are they trying to keep people from understanding are legitimate? Ultimately, you instead need to focus your article on the generation of doubt as a way to maintain the fossil fuel industry’s social and legal license to keep burning oil, gas, and coal. If you treat the misinformers’ frame as a legitimate, good-faith scientific critique, you are helping them produce doubt. Don’t do it. Don’t be a Merchant of Doubt. Thanks for reading The Climate Brink! Subscribe for free to receive new posts and support our work. Subscribe other stuff The Staying Curious Substack has an interesting post about the different flavors of climate sensitivity. This is crucial information if you want to understand how scientists think about how much warming the Earth will experience. I’d be grateful if you could hit the like button ❤️ below! It helps more people discover these ideas and lets me know what’s connecting with readers.
The Yankees Reliever Confidence Index: June Edition
David Bednar returns to form as Yanks’ relief unit remains surprisingly elite.
Sega Has Synthesized Sonic's DNA And Put It In A Chaos Emerald
"Oh, you mean Sonic's DNA?" Obama chuckled
Politics, Pubs, Parades, and the Parish: Joan Quigley, Part II
Former Assemblywoman Joan Quigley reflects on her legislative accomplishments, including helping pass New Jersey’s DNA evidence law.
These 20-Somethings Are Turning to Double Mastectomies | WSJ Health for June 12
Plus, scientists documented a controversial DNA-editing feat, and there’s a giant new wellness center in New York
Zelda: Ocarina Of Time Remake Can Wait, Twilight Princess Just Made A Triumphant Return
The Ocarina of Time remake has finally been confirmed, but Twilight Princess isn't going to let it have all the fun.
UT Austin researchers create nanoscale Longhorn using DNA origami
UT Austin researchers folded DNA into a nanoscale Longhorn, demonstrating a breakthrough that could help deliver cancer drugs more precisely and speed up the production of advanced materials.
Ancient DNA shared with Neanderthals may explain human language
A tiny set of ancient genetic “switches” may have played a surprisingly large role in making human language possible. Researchers found that these DNA regions, which act like volume controls for genes involved in brain development, have an outsized influence on language ability despite making up less than 0.1% of the genome.
Microbiology DNA and Chemistry for Health Insights Tops Research Schedule
Microbiology dominated the research schedule aboard the International Space Station on Thursday helping doctors protect health on Earth and in space. The Expedition 74 crew also tested a new spacesuit, packed a U.S. cargo spacecraft, and kept up lab maintenance throughout the orbital outpost.
Sydney Sweeney reacts to 'Euphoria' 'cast drama' rumors after final season
Sydney Sweeney responded to 'cast drama' rumors after 'Euphoria' ended with a heavily maligned final season, and spoke about 'clickbait' that's written about her.
Foley Hoag Advises Vesica Health in Sale to Photocure ASA
Learn more about the latest updates in legal, with expert commentary and insights from trusted attorneys from Foley Hoag LLP. Foley Hoag is a professional community of highly qualified attorneys from all over the US.
Vanderbilt Health and UAB partner to help more clinicians use genomic medicine in everyday care
The project will create a genomic eConsult service that allows clinicians to ask practical questions about genetic testing and interpretation.
President’s message: Progress and opportunity for science and medicine
his is an extraordinary moment in time for the biomedical sciences. Seven decades ago, the discovery of the structure of DNA sparked a revolution in understanding life. In the decades since, the knowledge of fundamental biology we have accumulated has led to innovative treatments for many difficult-to-treat diseases, and many more are now within reach....
Building trust and lab testing at the heart of DRC Ebola response: WHO
In Ebola-stricken eastern Democratic Republic of the Congo (DRC) a massive push for early testing and contact tracing is helping to contain the virus, the UN World Health Organization (WHO) said on Tuesday.
Your DNA is changing all the time. Here’s why
We tend to think of the DNA strands that contain our genetic code as consistent, stable units. But in reality, the cells that make up our bodies are constantly replicating and changing. Even as you read this sentence, in fact, the genes within your cells are mutating. So, what causes these mutations and what’s the impact? Science writer Roxanne Khamsi examines the answers in her new book, Beyond Inheritance. Today on the show, she gets into how scientists examine these mutations, how they’ve shifted our understanding of disease and what the future of genetic therapy could entail.Interested in more biological and life sciences? Email us your question at shortwave@npr.org.Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.
Southwest eyes deeper revamp; MAX 7 service seen in 2027
Southwest Airlines expects Boeing's long-delayed 737 MAX 7 to enter revenue service in 2027, about six months after the aircraft is certified by the U.S. Federal Aviation Administration, Chief Operating Officer Andrew Watterson told Reuters on Saturday.
Casagrande: Keep college football weird
College football is unlike any sport in the world. Let's not strip the weirdness from its DNA in the name of progress or money.
World Ocean Assessment highlights urgent need for science and global action
In the wood-panelled rooms of New York’s storied Explorers Club, where portraits of pioneering adventurers line the walls, diplomats, scientists and ocean advocates gathered on Tuesday evening with a shared sense of urgency – and anticipation.
Beluga whales keep switching mates and it may be saving their species
Hidden beneath Arctic waters, beluga whales have long kept their family lives a mystery. By analyzing DNA from more than 600 belugas in Alaska’s Bristol Bay over 13 years, researchers uncovered a surprisingly flexible mating system: both males and females regularly have offspring with different partners over their lifetimes.
Regional health agency issues measles alert for World Cup
As World Cup fever rises in the Americas, countries are urged to strengthen measles surveillance and vaccination amid ongoing outbreaks across the region.
Browns newly acquired DE Jared Verse's jersey number revealed
Dillon Gabriel is no longer wearing No. 8 for the Browns as Jared Verse has been spotted in his original number in Cleveland
Dodgers' Lack of Offense Proves Costly, Drops Series Opener in Arizona
The Arizona Diamondbacks hit three home runs as the Los Angeles Dodgers were unable to produce any offense
Banner employee facing sexual assault, kidnapping charges
The victim reported she felt if she yelled for help, she would be sedated or restrained.
A molecular path toward DNA health
UIC researchers identified a molecular pathway that supports healthy aging and cancer prevention.
How aid cuts are hampering the front-line response to the Ebola crisis
Aid workers in Uganda are watching an Ebola crisis unfold in neighboring Democratic Republic of Congo. They're doing what they can to prepare for an uptick in cases, but foreign aid cuts aren't helping.
Scientists discover inherited traits that break Mendel’s Laws of genetics
A major mouse study found that some inherited traits are passed down through epigenetic changes that break the classic rules of genetics. Researchers discovered hundreds of cases where these chemical DNA marks behaved unexpectedly, including some that seemed to emerge out of nowhere. They also identified the first known naturally occurring paramutation in a mammal, hinting that environmental influences may play a larger role in inheritance than scientists realized.
Yankees predicted to trade for Padres $4M All-Star flamethrower to form nasty duo with David Bednar
New York Yankees have an up and down bullpen and will surely be looking for some arms this deadline. They could go all in for one of the most powerful arms out of the bullpen.
DNA had one rule. Bacteria didn’t get the memo
Every cell in every organism on Earth copies DNA the same way. Except one bacterial protein — quietly doing something scientists had never seen before.
At Ramapo DNA lab, genealogy meets science to solve cold cases
Dozens of times over four years, researchers have hit on matches that bring closure to families and free the wrongfully convicted
Overnight Science Saturday News Digest May 30th, 2026
Grapefruit-sized hail may become more common in a warmer world New 3D silicon chip breakthrough could extend Moore’s Law for years | ScienceDaily Ancient DNA reveals how women helped transform…
Repairing DNA damage: Scientists discover a surprising new benefit of melatonin
A new study suggests melatonin supplements may help night shift workers boost their body's DNA repair processes, potentially offsetting some of the damage linked to working overnight. The findings are early but raise the possibility of a simple strategy to help reduce long-term health risks associated with night shift work.
Hidden in plain sight: DNA reveals 15 overlooked coral lineages in the Indo-Pacific
Scientists have discovered that one of the ocean's most recognizable corals, the iconic “organ pipe coral” — long believed to be a single widespread species — includes at least 15 genetically distinct lineages. Two of these lineages are currently known only from the Red Sea. The findings, publish
DNA solves 250-year-old mystery of the Seychelles’ lost crocodiles
Scientists have solved the mystery of the Seychelles’ vanished crocodiles using DNA from historic museum specimens. The reptiles were not a unique species after all, but an isolated population of saltwater crocodiles that likely drifted thousands of kilometers across the Indian Ocean.
Vanderbilt Health-led team wins NIH Replication Prize for biobank data quality tool
The team measures how reliably data in large DNA biobanks reproduces previously published genetic findings.
Ebola outbreak in DR Congo collides with conflict and hunger, WHO warns
The UN World Health Organization (WHO) on Wednesday warned that eastern Democratic Republic of the Congo faces a “catastrophic collision of disease and conflict” as a fast-spreading Ebola outbreak outpaces containment efforts in a region already battered by armed violence, mass displacement and acute hunger.
Scientists are raising new questions about vitamin B12 and cancer
Vitamin B12 has long been seen as a health hero, helping the body make red blood cells, repair DNA, and keep nerves functioning properly. But scientists are discovering that the story may be more complicated than simply “more is better.” While too little B12 can damage DNA and raise cancer risk, some studies suggest that extremely high levels — especially from long-term high-dose supplements — may also be linked to certain cancers or poorer outcomes in cancer patients.
Ebola epidemic spreading rapidly and outpacing containment efforts
There are more than 900 suspected cases of the Bundibugyo strain of Ebola in the Democratic Republic of the Congo, and 220 suspected deaths, the head of the World Health Organization (WHO), Tedros Ghebreyesus, said on Monday.
Franklin Primary Health Center offering free men’s health check-ups
June is Men’s Health month. Join us for our free men’s health checkup Thursday, June 4th at the Franklin Primary Health Center Medical Mall, and Friday, June 5th at the FOX10 Studio.
WHO chief calls for urgent Ebola action and pandemic preparedness
The recent Ebola and hantavirus outbreaks demonstrate that the world is still vulnerable to rapidly spreading infectious diseases, Tedros Ghebreyesus, the head of the World Health Organization (WHO), warned on Saturday at the close of the 79th World Health Assembly in Geneva.
WTAP+ | From 1 person to a full crew, roofing business helps families and homes across the Mid-Ohio Valley
In this episode, Stephanie Plant sits down with the owner of Rainstoppers Roofing in Marietta.
From Kharkiv to the UK’s health service: Ukrainian doctor rebuilds her life – and helps others do the same
On 23 February 2022, in her home city of Kharkiv, Dr Inna Soldatenko finished work, collected her daughter from school, cooked dinner and prepared a lecture for her students. The next morning, she awoke to explosions.
Scientists discover hidden weakness shared by hundreds of cancer mutations
Scientists have unveiled a powerful new tool called PerturbFate that could change how researchers tackle diseases driven by huge numbers of genetic mutations, including cancer and Alzheimer’s. Instead of trying to target every faulty gene individually, the system tracks how different mutations reshape cells over time and identifies the hidden “control hubs” where those pathways converge.
Exclusive: Why Adnan Sami Doesn't Care About Getting 'Pulled Into Politics' After Meeting RSS Chief
Adnan Sami said, "So the politics, it doesn't bother me anymore."
Transforming our future by unlocking the power of DNA: the representation of health-related genomic testing in UK news items
European Journal of Human Genetics - Transforming our future by unlocking the power of DNA: the representation of health-related genomic testing in UK news items
Scientists Warn Many Insects May Not Survive a Warming World
A sweeping study of tropical insects found that many species may struggle to survive rising global temperatures.
6,000-year-old humans with unique DNA are puzzling scientists - Futura-Sciences
The original hunter-gatherer group has no known modern descendants and no close ancient relatives. A study published in Science Advances details this isolated lineage. Led by Kim-Louise Krettek and senior author Cosimo Posth at the University of Tübingen, the project included collaboration with Andrea Casas-Vargas at the Universidad Nacional de...
Scientists Discovered A Population Developed a Genetic Superpower—Thanks to Potatoes
A new DNA study found that Peruvian Andeans possess a high number of salivary amylase genes, or AMY1, for digesting starchy foods like the native potato.
Scientists use DNA from poop to save the world’s rarest marsupial
Scientists in Australia are using cutting-edge DNA techniques to help save one of the world’s rarest marsupials — the critically endangered Gilbert’s potoroo, with fewer than 150 left in the wild. By analyzing tiny traces of DNA in the animals’ scat, researchers uncovered clues about the elusive fungi the potoroos depend on for survival. The findings could help conservationists identify safer new habitats and establish backup populations before disasters like bushfires wipe them out.
UT Health San Antonio researcher awarded $2.1M award to study cellular structures - UT Health San Antonio
Like a busy restaurant kitchen, our cells depend on well-organized working spaces to assemble the “recipes” that keep the body healthy. When these spaces are disrupted, important functions like gene regulation and DNA repair can go awry, promoting diseases such as cancer and neurodegeneration. UT San Antonio scientist David Libich, PhD, associate professor in […]
Yankees news: Could Gerrit Cole be activated on Friday?
Cole could come up for his next start; bullpen as a unit bad, Bednar particularly unreliable; retirements and callups
DNA floating in seawater is now enough to let scientists monitor the health of America's dolphin populations
DNA is everywhere in the world's oceans—not only packaged inside cells from skin, scales, mucus, feces, and blood, but also floating freely. Sequencing such "environmental DNA" (eDNA) from open water ...
DNA floating in seawater is now enough to let scientists monitor the health of America’s dolphin populations
Sequencing environmental DNA in seawater shows the local presence or absence of species, but until now could give little information about those measures of biodiversity that are the most useful in conservation. As a proof-of-principle, scientists in the US have now shown that mitochondrial DNA in water sampled near schools of dolphins contains enough information to measure their local effective population size and monitor the health of these populations.
Bird and Human Faces Share the Same Genetic Blueprint. Why Do They Look So Different?
Changes in non-coding DNA sequences make all the difference.
Scientists studied the DNA of a 117-year-old woman and what they found is changing how we understand ageing
Imagine having a 117th birthday celebration with a sharp mind, a strong heart, and enough energy for the daily walk. If you're Maria Branyas Morera, this was not just a wish; it was her reality.
AI piplines correctly identify genetic basis for disease
Large language models use reasoning capabilities to identify new genetic factors causing disease - even without any medical training.
David Bednar Stat is Very Concerning for Yankees' Future
It's been an ugly past week or so for the New York Yankees, a very concerning sign for a team that was one of the best in Major League Baseball prior to this. Now sitting at 28-19, the Yankees are 3-7 over their last 10 games and are three games behind the first-place Tampa Bay Rays in the American League East.
Scientists reveal more than 1.3 million people may share DNA with Maryland’s earliest colonists
According to new findings by researchers from Harvard University, there could be more than one million three hundred thousand individuals living today who share their genetic material with some of the original colonists of Maryland in the United States, as shown in an innovative genetic study titled ‘The genetic legacy of the 17th-century colonial capital of St. Mary’s City’ in Current Biology.
Scientists Discover Ancient “Language Switches” Hidden in Human DNA
Researchers have identified tiny genetic “switches” that appear to play a surprisingly large role in human language ability.
Arizona Diamondbacks Gameday Thread, #45: 5/17 @ Rockies
Today’s Lineups DIAMONDBACKS ROCKIES Ildemaro Vargas – 2B Edouard Julien – 2B Corbin Carroll – RF Mickey Moniak – LF Geraldo Perdomo – SS Hunter Goodman – DH Nolan Arenado – 3B TJ Rumfield – 1B Lourdes Gurriel – LF Troy Johnston – RF Adrian Del Castillo – DH Willi Castro – SS Gabriel Moreno […]
Ebola outbreak in Central Africa declared a ‘Public Health Emergency of International Concern’
The World Health Organization (WHO) has declared the ongoing Ebola outbreak in the Democratic Republic of the Congo (DRC) and Uganda a Public Health Emergency of International Concern, citing rising cases, cross-border spread and significant uncertainties about the scale of the epidemic.
🚨 Official: Xabi Alonso joins Chelsea
Thunderbolt in the Premier League!Chelsea officially announced this Sunday morning that Xabi Alonso will take over as head coach starting next season!The former Anfield darling thus becomes the new ma...
Microsoft admits customization is in Windows' DNA, promises new Windows 11 controls
Microsoft says Windows has personalization and customization in its DNA, and it plans to roll out new features over the coming months.
Scientists discover why some cancers survive chemotherapy
Scientists have uncovered a surprising new trick used by one of cancer’s most notorious proteins. MYC, already infamous for fueling runaway tumor growth, also appears to help cancer cells survive by repairing their damaged DNA — including damage caused by chemotherapy and radiation. Researchers found that MYC can rush directly to broken DNA and recruit repair machinery, effectively helping tumors recover from treatments meant to destroy them.
A grad student’s wild idea sparks a major aging breakthrough
A casual conversation between graduate students helped spark a breakthrough in aging research at Mayo Clinic. Researchers discovered that tiny synthetic DNA molecules called aptamers can selectively attach to senescent “zombie cells,” which are linked to aging, cancer, and neurodegenerative disease. The method could eventually help scientists identify and target these cells in living tissue with far greater precision.
AMD promises to bring improved, hardware-backed FSR 4 upscaling to older Radeon GPUs
FSR 4.1 running on RDNA3 or RDNA2 GPUs may take a bigger performance hit.
Craig Venter obituary
Pioneering and controversial geneticist who was one of the first to sequence the human genome, in part by using his own DNA
AMD FSR Upscaling 4.1 officially coming to Radeon RX 7000 GPUs in July, RX 6000 in 2027
Breaking, AMD confirms FSR 4.1 for Radeon RX 7000 series After months and often years of waiting, AMD is finally confirming support for FSR4 on RDNA3 and
Scientists say a daily multivitamin may help slow aging
A daily multivitamin may help slow biological aging, according to researchers studying older adults in a large clinical trial. After two years, participants taking multivitamins showed slower aging in several DNA-based “epigenetic clocks,” with the effect equal to about four months less biological aging. People who started out biologically older than their actual age appeared to benefit the most. The findings hint that a simple supplement could play a role in healthier aging.