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Noah Wyle announced as PEOPLE’s 2026 Sexiest Man Alive

‘The Pitt’ heartthrob Noah Wyle was announced as PEOPLE’s Sexiest Man Alive — nearly 30 years after ‘ER’ costar George Clooney was first crowned.

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Oct 27 • 6:01 AM EDT • Entertainment • ew.com
Anthropic’s nearly 100-page list of business risks includes everything from bioweapons to AI blackmail

There are massive and wide-ranging list of potential roadblocks, like making it a target of expensive lawsuits, and concerns that its own product could grow out of humanity’s control.

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Oct 27 • 6:00 AM EDT • Business • cnn.com
Congo’s Ebola outbreak tops 10,000 cases as authorities race to slow the spread in African countries

It is the fastest-growing Ebola outbreak in history and nearly half of the people confirmed to have the virus have died, according to data from Congo’s Ministry of Health.

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Oct 27 • 5:23 AM EDT • Health • nbcnews.com
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Poll: Likely voters favor Democrats as Trump disapproval drives early turnout

Democrats hold an 8-point lead among likely voters in the fight for control of Congress with one week until Election Day, according to the latest PBS News/NPR/Marist poll.

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Oct 27 • 5:00 AM EDT • Politics • pbs.org
UK's Channel 4 shows to launch on Disney+ next year

LONDON, Oct 27 (Reuters) - Channel 4 has signed a deal with The Walt Disney Company to bring its shows to the Disney+ streaming platform in Britain and Ireland early

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Oct 27 • 4:37 AM EDT • Entertainment • centraloregondaily.com
Could meals help keep older adults from returning to the hospital?

Research found that food-insecure older adults who received two weeks of home-delivered meals after hospitalization had lower odds of early readmission.

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Oct 27 • 3:33 AM EDT • Health • northcarolinahealthnews.org
Australia's Star Entertainment surges 13% as cost cuts, casino strength drive profit

By Keshav SinghChundawat and Sneha Kumar Oct 27 (Reuters) - Star Entertainment closed 13% higher on Tuesday after the casino operator swung to profit for the first time in nearly

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Oct 27 • 2:29 AM EDT • Entertainment • centraloregondaily.com
I’m a brain expert. Here’s why we must treat Alzheimer’s like cancer

Our series The Expert View brings you specialist health advice from professionals. Here, Dr Emer MacSweeney, a consultant neuroradiologist and co-founder of Re Health, explains why early diagnosis and access to new treatments could transform Alzheimer’s care.

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Oct 27 • 2:00 AM EDT • Health • health.yahoo.com
Apple responds to early screen flaws on $1,999 foldable iPhone Duo

Apple’s foldable iPhone Duo faces early screen issues near the hinge.

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Oct 27 • 1:12 AM EDT • Technology • seekingalpha.com
Dante Moore not expected back this season for Oregon — leaving NFL Draft status uncertain

Moore has not played since getting concussed on a late hit at Southern California in late September. He resumed practicing earlier this month but remained in the concussion protocol.

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Oct 27 • 1:03 AM EDT • Sports • sports.yahoo.com
The midterms look good for Democrats — but it’s too early to call a blue wave

The United States may be within a week of momentous political change in midterm elections that could destroy the Republican Party’s monopoly on Washington and hand Democrats power to check President Donald Trump.

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Oct 27 • 12:01 AM EDT • Politics • cnn.com
Omaha business owner pushes mayor for earlier path to trades

Mayor John Ewing Jr. held a town hall Monday night, updating residents on public safety, affordable housing and small business opportunities.

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Oct 26 • 11:28 PM EDT • Business • wowt.com
Omaha business owner wants earlier path to trades

Dupree Seavers, owner of Black Power Redevelopers, raised concerns about access to the trades and city contracts for small businesses.

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Oct 26 • 11:27 PM EDT • Business • wowt.com
Skydance offers voluntary buyouts to some employees

Skydance Corp. is offering some employees a one-time voluntary buyout, a move that comes nearly three weeks after Paramount Skydance closed its $111 billion acquisition of Warner Bros. Discovery. The

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Oct 26 • 8:42 PM EDT • Entertainment • thederrick.com
New York’s minor parties fight to maintain ballot access

As early voting gets underway in New York, the race for governor is also testing the political strength of two of the state’s most influential minor parties.

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Oct 26 • 8:10 PM EDT • Politics • spectrumlocalnews.com
Smithsonian scientists just recreated the first 2 billion years of the Universe

Scientists have created one of the largest and most detailed simulations of the early universe ever made, offering an extraordinary new glimpse into the cosmos shortly after the Big Bang. Called Lumina, the groundbreaking simulation recreates the universe’s first 2 billion years, showing how dark matter, gas, and radiation interacted to give rise to the earliest stars, galaxies, and black holes.

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Oct 26 • 8:00 PM EDT • Science • sciencedaily.com
Ashland officer shoots man after police respond to business alarm

A police officer shot a man early Monday near downtown after responding to a business alarm, according to the Ashland Police Department.

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Oct 26 • 7:44 PM EDT • Business • opb.org
Anthropic IPO filing reveals AI profits and $800 billion compute risk

Anthropic's IPO filing shows AI can be profitable at scale. Nearly $800 billion in computing deals pose a major risk.

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Oct 26 • 7:38 PM EDT • Business • businessinsider.com
Early voting surges across New York as Hochul, Blakeman make final push

More than 485,000 New Yorkers cast ballots during the first two days of early voting, compared to more than 262,000 during the same period four years ago.

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Oct 26 • 7:09 PM EDT • Politics • spectrumlocalnews.com
Here's How The Way Activision Talks About Call Of Duty Launch Weekend Sales Has Changed Over Nearly 20 Years

It hasn't been bragging about Modern Warfare 4 sales despite rave reviews

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Oct 26 • 6:30 PM EDT • Technology • kotaku.com
Florida voters — almost 2.8M — surge past '22 midterm benchmark as early voting goes statewide

The first weekend of early voting being available in every Florida county pushed the number of votes cast for the Nov. 3 election towards 2.8 million, more than 20 percent of the turnout in the prior midterm election in 2022.

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Oct 26 • 5:32 PM EDT • Politics • wusf.org
Texas Senate candidates offer differing economic visions

Feeling the financial squeeze has become a major motivation for Texas voters to head to the polls early.

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Oct 26 • 5:21 PM EDT • Politics • spectrumlocalnews.com
Can Holograms Help Schools Address the Student Mental Health Crisis?

A Staten Island high school is opening a nearly $500,000 wellness studio that will connect students with remote therapists through 3D technology, testing a new approach to school-based mental health care.

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Oct 26 • 5:11 PM EDT • Health • governing.com
Blue Frog founder John Campbell named group CEO of Avidly

Avidly, a global technology services company specializing in customer relationship management and go-to-market solutions, appointed Blue Frog Founder John Campbell as group CEO, effective Oct. 7. Campbell leads the company, which has nearly 300 employees across nine countries, from its North American offices in Waukee. He will continue serving as CEO of Blue Frog. Campbell…

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Oct 26 • 4:28 PM EDT • Business • businessrecord.com
Fearless Podcast: Special episode: Power of Fearless

Earlier in 2026, Jenna Feeney wrote an essay for Fearless about how she’s counteracting the risks she faces because of adverse childhood experiences. She had learned about ACEs from a previous essay published in Fearless in 2023, written by Krista Tedrow. It wasn’t planned, but on the day Jenna’s column ran in Fearless this past…

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Oct 26 • 4:02 PM EDT • Business • businessrecord.com
Gov. Wes Moore, up for reelection in Maryland, campaigns in Virginia

With victory expected at home, Moore is wooing Black and veteran voters in a 2028 early presidential primary state.

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Oct 26 • 3:24 PM EDT • Politics • washingtonpost.com
Emberville Delays Early Access Launch at the Last Minute

Cygnus Cross, the development team behind the promising "Diablo meets Stardew Valley" game Emberville, has delayed their Early Access launch the day before it was supposed to happen. The new Early Access release date is January 7 ,2027. To soften the blow the team says that the content originally planned for its first major post-launch update will now be included in the January 7 Early Access release.

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Oct 26 • 3:08 PM EDT • Technology • ign.com
Hochul, Blakeman hit the streets to encourage early voters

New York Democrats and Republicans were out in full force Saturday.

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Oct 26 • 2:42 PM EDT • Politics • spectrumlocalnews.com
Former Sarasota Big Lots to get new life as antique mall

Nearly 50 antique and collectible vendors have signed up to sell their wares in the former Big Lots, which is being transformed into an antique mall.

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Oct 26 • 2:14 PM EDT • Business • businessobserverfl.com
Spark Capital is the only VC firm mentioned in Anthropic's S-1

Anthropic's IPO paperwork mentions Spark Capital more than 50 times, reflecting Yasmin Razavi's early investment and board seat at the AI company.

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Oct 26 • 2:05 PM EDT • Business • businessinsider.com
Wilmington Health facility sells for $9.4M

Wilmington Health’s main facility recently sold for more than $9 million. The 66,000-square-foot facility located at 1202 Medical Center Drive was purchased by Charlotte-based real estate investment firm Cedar Square in a $9.4 million sale-leaseback transaction, according to a deed recorded Oct. 21. Wilmington Health will continue leasing the facility, CEO Jeff James told the Business Journal in September. James said the lease term would likely be five years, with most services eventually transferring to a new medical office building under construction in the Midtown Park office area near The Pointe at Barclay. The Wilmington Health facility was originally listed earlier this year at $11.85 million. A Wilmington Health representative did not respond to a request for comment by press time. Steve Hall, vice president of BlueCoast Commercial, represented Wilmington Health in the transaction. “Wilmington Health wanted to unlock the value in its real estate without disrupting a single patient visit, and a sale-leaseback let them do exactly that,” said Hall in a text to the Business Journal Monday. “Cedar Square gets a long-term, absolute net investment anchored by one of the region’s leading physician groups, and Wilmington Health keeps its home on Medical Center Drive while redeploying that capital into care.” The sale marks Cedar Square’s first entry into the Wilmington market, according to Jon Dixon, the firm's managing partner and founder. “We are attracted to Wilmington's growth and what we see as strong long-term fundamentals,” said Dixon in an email Monday. “Population growth, relative affordability, and quality of life make it a compelling market for us. The climate and proximity to the coast are a big part of that appeal.” He added, “We hope to pursue additional opportunities across retail, industrial, medical office and multifamily in Wilmington. We will evaluate opportunities individually and remain disciplined about the properties we pursue. We would like this acquisition to be the beginning of a broader investment presence in Wilmington.” Given the facility’s age, Dixon said the site could eventually be redeveloped, potentially for medical office space or housing. Dixon said recent announcements from UNC Health and Atrium were among the factors behind the firm’s growing interest in Wilmington’s medical-office market. The announcements involve competing proposals for hospital expansion in New Hanover County, which are subject to the state’s Certificate of Need process. “Medical office remains one of the most sought-after asset classes in commercial real estate,” said Hall, “and well-located (medical office buildings) with strong operators are scarce in Southeastern North Carolina.” According to Dixon, Cedar Square describes itself as a boutique, hands-on real estate investment firm that values direct relationships with tenants and the communities where it owns property. “We’re very hands-on, and we like to be in direct contact with all of our tenants and the communities in which we own,” Dixon said. He added, “We’re definitely interested in building a presence with local owners, brokers and businesses or tenants.”

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Oct 26 • 1:58 PM EDT • Health • wilmingtonbiz.com
Mike Macdonald: "Early returns are positive" on Rashid Shaheed's knee
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Oct 26 • 1:23 PM EDT • Sports • sports.yahoo.com
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Apple’s Foldable iPhone Duo Draws Early Complaints of the Screen Cracking

The iPhone Duo, one of Apple Inc.’s biggest new products in years, is drawing a growing number of complaints from customers who say the foldable display cracked after just hours or days of use.

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Oct 26 • 1:13 PM EDT • Technology • finance.yahoo.com
Is Rayquaza Broken? Delta Reign Set Preview

Our new set Delta Reign is getting some hype because of the crazy new engine based around Mega Rayquaza ex. This deck is clearly good, and it's already

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Oct 26 • 1:00 PM EDT • Technology • pokebeach.com
Follow the science

By Robert Royal Surveys of young people show that many lose their faith because they believe science has refuted religion. Among many other factors, this error is a major challenge for the Church, one that does not receive nearly the…

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Oct 26 • 12:26 PM EDT • Science • infovaticana.com
Power, packaging companies approved for projects bringing 180 jobs to Northeast Ohio

Two companies, Avtron Power Solutions and Spray Products are expanding their current operations, adding 180 jobs and maintaining nearly 450 existing positions.

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Oct 26 • 12:12 PM EDT • Business • crainscleveland.com
Ashland police shoot armed man after numerous businesses vandalized

Officer-involved shooting occurred around 2 a.m. on A Street following reports of business alarm An unidentified man was shot early Monday morning after he approached Ashland police officers with a […]

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Oct 26 • 11:46 AM EDT • Business • rv-times.com
Intel Core Ultra 4000 Nova Lake-S leak: 28-core CPU beats Core Ultra 9 285K in single-thread test

Early Nova Lake-S benchmark results suggest improved single-thread performance over Arrow Lake. However, the 28-core sample still trails Core Ultra 9 285K in the overall CPU Mark test.

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Oct 26 • 11:41 AM EDT • Technology • videocardz.com
Hands-On: A. Lange & Söhne Datograph Perpetual Calendar—With Diamonds And A Bracelet

By giving collectors exactly what they've asked for, the brand has created nearly a perfect, quintessential Lange.

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Oct 26 • 11:00 AM EDT • Technology • hodinkee.com
Development battles, business worries and election season in Brunswick

Development projects, early voting, fatal collisions, business closings and more are pushing Brunswick County residents to the brink as October winds down.

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Oct 26 • 10:55 AM EDT • Business • charlotteobserver.com
Development battles, business worries and election season in Brunswick

Development projects, early voting, fatal collisions, business closings and more are pushing Brunswick County residents to the brink as October winds down.

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Oct 26 • 10:55 AM EDT • Business • newsobserver.com
What You Learn in Preschool May Affect Your Mental Health Nearly 20 Years Later

Tracking 356 Head Start preschoolers for nearly 20 years proves that brief, twice-weekly lessons in emotional awareness and conflict resolution significantly reduce adult depression and loneliness whi...

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Oct 26 • 10:41 AM EDT • Health • yahoo.com
Arkansas basketball frontcourt is obvious point of focus

If Arkansas has a question mark, it's clearly the frontcourt

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Oct 26 • 10:26 AM EDT • Sports • sports.yahoo.com
Bon Secours Mercy Health affiliate will buy Surgery Partners for about $5.7 billion

Surgery Partners shareholders other than Bain Capital would receive $23.50 a share in cash; the deal is expected to close in early 2027

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Oct 26 • 10:10 AM EDT • Health • qz.com
Suspect shot after reports of break-in at Ashland businesses, police say

Ashland Police shot someone early Monday morning after responding to reports of a break-in alarm at a business.The person, who has not yet been identified, was

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Oct 26 • 10:02 AM EDT • Business • katu.com
Manchester City owners provide another €23m to Lommel

Manchester City’s owners have provided a capital investment of around €23m into Lommel. As reported by HLN, the owners of Manchester City have now invested nearly €100m over the last six years. ...

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Oct 26 • 7:58 AM EDT • Sports • sports.yahoo.com
Trump will campaign in deep-red Mississippi in latest sign of GOP midterm worries
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Oct 26 • 7:55 AM EDT • Politics • cnn.com
8 Players Withdraw from ATP Vienna & Basel

The 2026 ATP season has nearly come to a close, and it’s in the middle of the final push, with 500s in Vienna and Basel leading up to the Paris Masters and the ATP Finals. Several players won’t be able to finish their seasons strong, though, as they have withdrawn from these two stacked draws. …

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Oct 26 • 7:15 AM EDT • Sports • sports.yahoo.com
Cameron Boozer Update: Rolling Right Along

It’s still early, but Cameron Boozer is quickly establishing himself in the NBA

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Oct 26 • 6:45 AM EDT • Sports • sports.yahoo.com
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Samsung slices into Apple's iPhone Duo troubles with a cheeky new ad

A Samsung Galaxy Z Fold 8 ad pokes fun at Apple's iPhone Duo as early screen cracking reports fuel the foldable rivalry.

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Oct 26 • 6:44 AM EDT • Technology • androidauthority.com
Think your boss is bad? Scientists identify history’s first official ‘corporate psychopath’

People motivated by power, wealth, and personal advancement were attracted to capitalism from its earliest days

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Oct 26 • 6:36 AM EDT • Science • yahoo.com
Convicted business manager cost Columbus charter school nearly $500,000, audit finds

A former Columbus charter school business manager convicted of theft is responsible for nearly $500,000 in losses, according to a state audit.

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Oct 26 • 6:30 AM EDT • Business • nbc4i.com
In his own words: Trump on gas prices and energy costs since launching the war with Iran

Since launching the war with Iran nearly eight months ago, U.S. President Donald Trump has struggled to quell soaring energy costs, undermining Republicans’ attempt to keep control of Congress in the midterm elections next week.

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Oct 26 • 6:25 AM EDT • Politics • ksat.com
1 In 5 Young Adults Feel Anxiety Every Single Day, Study Says

By Dennis Thompson HealthDay ReporterMONDAY, Oct. 26, 2026 (HealthDay News) — Nearly 1 in 5 young adults in the U.S. feel anxious every single day, a new study says. Just under 20% of Americans between 18 and 25 said they suffered from daily anxiety in 2024, up from 15% in 2020, researchers report ...

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Oct 26 • 6:15 AM EDT • Health • usnews.com
Need help deciding on the state ballot measures? Here are my recommendations

You haven’t voted yet because the state propositions are too bewildering? I’m with you.

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Oct 26 • 6:00 AM EDT • Politics • latimes.com
Trump’s D.C. hotel is gone. Mar-a-Lago is now a GOP campaign cash magnet.

Republican campaigns, party committees and PACs have spent nearly $3 million at Trump businesses since his return to office, a Post analysis finds.

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Oct 26 • 6:00 AM EDT • Politics • washingtonpost.com
Match Gallery: Hibernian v Celtic

Celtic came back along the M8 on Sunday with all three points after coming from behind to win 2-1 against Hibernian.The home side took an early lead from a quickly-taken free-kick but that was soon fo...

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Oct 26 • 5:51 AM EDT • Sports • sports.yahoo.com
BGOV OnPoint: Small Business Contracting Competition in Flux

A proposed overhaul of small business eligibility standards could expose nearly 57,000 small federal vendors to larger rivals, including publicly traded companies.

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Oct 26 • 5:05 AM EDT • Business • news.bgov.com
Jonathan Groff to star in Broadway production about Nickel Mines tragedy

Ronks-native actor Jonathan Groff will return to the Big Apple in early 2027 to star in a Broadway production about the Nickel Mines tragedy.

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Oct 26 • 5:00 AM EDT • Entertainment • lancasteronline.com
115-year-old Pan-American Life Insurance Group on track to surpass $2B in revenue

Insurance industry veteran José Suquet's bags were nearly packed for a job in Miami in 2004 when recruiters looking to fill the top job at Pan-American Life Insurance Group in

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Oct 26 • 5:00 AM EDT • Business • nola.com
Trump’s name was everywhere in earlier Louisiana elections. What about this time?

Both Republican and Democratic candidates in Louisiana seem to avoid mentioning the president.

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Oct 26 • 5:00 AM EDT • Politics • nola.com
Smithsonian scientists launch "Lumina" simulation to model early universe

Researchers introduce "Lumina," a massive cosmological radiation-hydrodynamics simulation designed to model the universe's first two billion years

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Oct 26 • 4:56 AM EDT • Science • openaccessgovernment.org
Local businesses weather the effects of international Geneva cuts

For nearly two years, restaurants, hotels, and other parts of the local economy have grappled with the effects of international Geneva job and budget cuts, particularly around the Nations quarter. Two publicly backed studies are now seeking to quantify the losses.

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Oct 26 • 12:47 AM EDT • Business • genevasolutions.news
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The Rise of Independent Voters Is Reshaping American Politics

In this Fulcrum Roundtable discussion, Jeremy Gruber of Open Primaries explains why voters are leaving the major parties, how closed primaries limit participation, and what reforms could expand representation for nearly half the country.

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Oct 26 • 12:40 AM EDT • Politics • thefulcrum.us
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Six health checks men need to stop putting off

Across developed economies, the rate of avoidable and preventable deaths among men is more than double that of women, OECD data shows. This is in large part due to men being reluctant to see a doctor until a health issue becomes too severe to ignore, but early diagnosis often means a better outcome.

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Oct 26 • 12:03 AM EDT • Health • health.yahoo.com
Lula is declared winner of Brazil's election as Bolsonaro rejects results

Flavio Bolsonaro is refusing to concede defeat to incumbent President Luiz Inácio Lula da Silva, who bested him by nearly 4.4 million votes, following a chaotic delay in poll closing

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Oct 25 • 10:27 PM EDT • Business • yakimaherald.com
Stray gunfire hits business after early-morning shooting in the Tower District

A business in the Tower District was hit by stray gunfire on Sunday.Fresno Police officers responded to a reported shooting in the area of Fulton and Dennett a

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Oct 25 • 9:49 PM EDT • Business • kmph.com
Il Volo celebrates nearly 20 years of musical harmony

Longer than many marriages and most rock bands, the Italian singing trio Il Volo have been together for almost 20 years. They’ve gone from teenagers to 30-somethings while selling more

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Oct 25 • 9:00 PM EDT • Entertainment • floridaweekly.com
Cubs Trade Of Edward Cabrera An Early Lose-Lose Deal

A high-stakes gamble for Edward Cabrera backfired in Chicago as the right-hander's metrics plummeted, leaving the North Siders searching for answers amidst a looming rotation crisis.

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Oct 25 • 8:39 PM EDT • Sports • sports.yahoo.com
Fresno police investigate shooting at Airbnb rental in Tower District

The Fresno Police Department is investigating a shooting that occurred early Sunday morning in a Tower District neighborhood.

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Oct 25 • 8:14 PM EDT • Business • abc30.com
6 stellar images of the early universe

The most detailed simulation of our universe’s first 2 billion years to date.

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Oct 25 • 8:01 PM EDT • Science • popsci.com
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Chinese scientists discover “D-rex,” a giant fungus with roots stretching back 65 million years

Scientists have discovered a giant new fungus in China that grows up to 20 inches tall and weighs nearly five pounds, making it the largest known of its kind. Dubbed “D-rex,” its evolutionary lineage appears to have emerged shortly after the dinosaurs went extinct, raising intriguing questions about how that ancient catastrophe may have shaped its evolution.

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Oct 25 • 8:00 PM EDT • Science • sciencedaily.com
Scientists discover Arctic sea ice loss could be far worse than predicted

Arctic winter sea ice could disappear much faster than scientists previously expected, according to new research using climate clues from 6,000 years ago. By comparing ancient ocean sediments with modern climate models, researchers found that future winter ice coverage may be roughly one million square kilometers smaller than earlier predictions suggested.

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Oct 25 • 8:00 PM EDT • Science • sciencedaily.com
Jenna Ortega ‘almost fell on’ her face after shooting ‘Iron Man 3’ film debut (exclusive)

Jenna Ortega recalls ‘limping’ home and nearly falling on her face after shooting her film debut in ‘Iron Man 3.’

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Oct 25 • 7:59 PM EDT • Entertainment • ew.com
Early voting underway in Michigan

Early voting began Saturday, Oct. 24 in Michigan. County officials say the first day of early voting went well and more than half of mail-in ballots have already been returned.

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Oct 25 • 6:51 PM EDT • Politics • abc12.com
With flu season off to an unusually early start, here's what doctors are seeing

It's not even Halloween yet, but doctors say flu season off to an unusually early start.

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Oct 25 • 6:39 PM EDT • Health • nbcchicago.com
Kenilworth's David Brearley 2026 Homecoming Photo Album

KENILWORTH, NJ – The Homecoming Dance was held on Friday, Oct. 16, and students were filled with energy and excitement as they left for the annual occasion held at David Brearley.To preserve the...

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Oct 25 • 4:48 PM EDT • Entertainment • tapinto.net
When will Myles Garrett return to the Rams?

Here's the latest on Myles Garrett as he continues recovering from early-season knee surgery.

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Oct 25 • 4:06 PM EDT • Sports • sports.yahoo.com
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How Pratt Proved Brewers Right in the World Series

Shrugging off an early error, rookie Cooper Pratt delivered a clutch game-winning hit, vindicating the Milwaukee Brewers long-term investment.

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Oct 25 • 4:00 PM EDT • Sports • sports.yahoo.com
Erick All leaves Week 7 game early

Bengals TE Erick All ruled out after suffering a knee injury in Week 7

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Oct 25 • 3:42 PM EDT • Sports • sports.yahoo.com
Binaytara Implementation Science Research Awards 2027 - Oncology News, Insights, Stories by OncoDaily

The Binaytara Implementation Science Research Awards 2027 provide up to $25,000 per project to support early-career investigators improving how evidence-based

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Oct 25 • 2:15 PM EDT • Science • oncodaily.com
Warriors honor Bay Area sports reporter Michael Wagaman

After Michael Wagaman passed away in early August, Dallas Braden took time to tribute him during his call of the Athletics’ game on NBC Sports Bay Area and California. Wagaman had covered Bay Area sports teams since 1996, including for the Associated Press, and freelanced for NBC Sports Bay Area and California at the time…

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Oct 25 • 12:30 PM EDT • Sports • sports.yahoo.com
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Googlebook is getting AAC Bluetooth audio and key fixes for Cast My Apps

As we talked about earlier this week, every brand-new platform goes through growing pains right out of the gate, and Googlebook OS is no exception. While we've already seen Google step up to...

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Oct 25 • 11:41 AM EDT • Technology • chromeunboxed.com
ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals

Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.

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Oct 25 • 11:30 AM EDT • Health • fiercebiotech.com
Their friend died of cervical cancer in 2020. Now, they advocate for women’s health in N.S.

Following the death of their close friend from cervical cancer in 2020, two women in Nova Scotia were left wondering how things might have been different had she been diagnosed earlier. Six years later, they have raised over $4 million to improve technology and infrastructure for women's health.

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Oct 25 • 11:05 AM EDT • Health • cbc.ca
Evaluating DJ Herz After Bouncing Back from Injury with Nationals

After making his first MLB appearance in nearly two years, what should the Washington Nationals expect from DJ Herz in his third season with the organization?

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Oct 25 • 10:56 AM EDT • Sports • sports.yahoo.com
Face the Facts: New health insurance helps early childhood educators

Child care is expensive, and keeping qualified workers on the job is part of the challenge. Now, Connecticut is offering a new health insurance subsidy to help early childhood educators lower their monthly premiums. Rep. Kate Farrar (D-West Hartford) explains how it works and why it could make a difference for families. Mike Hydeck: For years, Connecticut has had among…

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Oct 25 • 10:48 AM EDT • Health • nbcconnecticut.com
Obama, in Midwest, assails 'cruelty' and indecency from Trump and his allies in the midterm campaign

Obama remains the Democratic Party’s best motivator nearly a decade after leaving the White House. And he's taking his star power on the road in the final days of the midterm elections, which will help determine the balance of power in American politics on Nov. 3.

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Oct 25 • 10:35 AM EDT • Politics • pbs.org
Can social media bans protect young people’s mental health? Early research suggests that bans aren’t the answer

About 20 countries are looking to ban minors from social media. But bans have not always worked as planned. Here are some other ideas to make platforms safer for kids.

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Oct 25 • 10:01 AM EDT • Health • inquirer.com
Week 7 Early Games Open Thread

The only games I’m really keyed in on are the Steelers and Texans both losing to the NFC team and then decided which team between the Bengals and Ravens are the bigger threat to Denver’s future playoff seeding arrangement. Here are the games we have to watch today before the Denver Broncos take on the […]

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Oct 25 • 9:25 AM EDT • Sports • sports.yahoo.com
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US employer health insurance premiums exceed $28,000 for family coverage in 2026

US employer health insurance premiums rose 5% in 2026, exceeding $28,000 for family coverage, while nearly half of working-age adults lack adequate coverage

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Oct 25 • 7:54 AM EDT • Health • beinsure.com
South Texas Health System (@stxhealthsystem)

2 likes, 1 comments - stxhealthsystem on October 25, 2026: "One Last Chance to Think Pink: Breast cancer remains the most common cancer among women after skin cancer, making routine screenings and early detection more important than ever. Mammograms can help identify breast cancer before symptoms appear, when treatment options may be most effective. Last week, South Texas Health System McAllen celebrated breast health and preventive care with a special Mammo Monday event featuring the vibrant sounds of mariachi music at the hospital’s main entrance. The celebration reflected STHS' ongoing commitment to encouraging women to prioritize their health through regular screenings. Now, there’s one final Mammo Monday remaining! Join us at STHS ER Mission on October 26 from 8 a.m. to 5 p.m. for the last breast cancer event of 2026. During the event, attendees can: 🎀 Learn about breast cancer screening options 🎀 Schedule a mammogram appointment 🎀 Receive a complimentary goodie bag while supplies last To help make preventive care more accessible, South Texas Health System is also offering reduced self-pay rates* throughout October: • 2D Mammogram: $100 • 3D Mammogram: $155 • Bone Density Screening: $160 A screening today could make all the difference tomorrow. Make your health a priority and encourage the women you love to do the same. For breast health resources and information on the Think Pink campaign, visit the link in our bio. *If not already a covered benefit of your insurance.".

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Oct 25 • 7:41 AM EDT • Health • instagram.com
CBS News political experts weigh in on Texas Senate race halfway through early voting

The latest CBS News poll​ showed Talarico leading 51% to 49%, well within the margin for error.

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Oct 25 • 7:00 AM EDT • Politics • cbsnews.com
High-Signal Publisher
Amendment 87 can help support Colorado health care; no to tax increases; and more (Letters)

Amendment 87 gives Colorado a way to respond to our health care affordability crisis. New income tax revenue would be set aside for health care, K-12 public schools, and early child care, with an annual independent audit. For 97% of…

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Oct 25 • 6:00 AM EDT • Health • dailycamera.com
How to catch the hunter’s moon this weekend

An orange-colored full hunter’s moon will reach peak brightness early Monday morning along with a potential glimpse of Saturn.

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Oct 25 • 6:00 AM EDT • Science • cnn.com
Early voting underway in upstate New York

Early voting continues through Nov. 1 and Election Day is Nov. 3.

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Oct 25 • 6:00 AM EDT • Politics • spectrumlocalnews.com
Hochul, Blakeman hit the campaign trail as early voting begins

Both Kathy Hochul and Bruce Blakeman’s campaigns are escalating their attacks over affordability and the governor's record.

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Oct 25 • 6:00 AM EDT • Politics • spectrumlocalnews.com
Guest Commentary: How anti-Muslim politics endangers every Floridian

The political caricature of Muslims as a national security threat bears little resemblance to the reality that Floridians are living, working, and raising families in peace with nearly half a million Muslims woven into the fabric of the state.

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Oct 25 • 5:30 AM EDT • Politics • orlandosentinel.com
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Job-based health plan costs rise, with little relief in sight

Nearly half of large employers have increased the amount their workers must pay for health insurance — a response to rising premiums.

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Oct 25 • 5:01 AM EDT • Health • phillyvoice.com
State College Area Liquor Store Moving to New Location

A State College area liquor store will move a short distance to a new location early next year. The state-owned Fine Wine & Good Spirits store at 127

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Oct 25 • 3:00 AM EDT • Business • statecollege.com
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