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Buffalo Bills roster cuts tracker, 2026

The Buffalo Bills must reduce their 91-man roster by a total of 38 players to meet the NFL’s 53-man mandate by August 30.

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Aug 27 • 10:24 PM EDT • Sports • sports.yahoo.com
Common vaccine linked to 24% lower dementia risk in older adults

A Brown University study found Shingrix reduced dementia risk by 24% over four years, building on prior research linking the shingles vaccine to brain health.

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Aug 27 • 10:21 PM EDT • Health • foxnews.com
The Literacy Crisis Reaches Dog-Bear Science

“New analysis of more than 300 bear encounters suggests our canine companions often increase odds of conflict and rarely serve as early warning systems many recreationists assume,” reads a subhead in Mountain Journal. The thing is, that study reaches no such conclusion. But you have to read beyond the abstract to understand that. Mountain Journal is not alone. Let’s look at a brief list of takeaways published elsewhere just to establish that none of them seem to know how to read science. Wes Siler’s Newsletter is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe Here’s CBC: “A new peer-reviewed study, The Canine Conundrum: Is a Dog a Help or Hindrance in Bear Country?, dug into conflicts similar to what the video depicts, by analyzing 326 reported human-bear conflicts from 1901 to 2023 involving dogs.” “The study found 54 per cent of conflicts were started by dogs. In the encounters researchers included in the study, five people and 56 dogs were killed, and 170 people were injured.” “Lana Ciarniello, an independent researcher who co-authored the study, said researchers found when a person goes hiking with at least one other person, the odds of a negative bear encounter decrease by 50 per cent.” “However, when a dog is involved, the chances of a negative bear encounter increase because ‘a dog really adds a chaotic factor into the mix of recreation,’ said Ciarniello.” Again, the study finds no data supporting that conclusion. “Hiking with your pet dog may make you feel safer in bear country—but a hiker’s recent encounter and a new study prove that the numbers don’t add up,” writes Backpacker, which is now part of Outside. The numbers don’t add up to support this take. There’s plenty more examples, but all are equally dumb, so I’ll stop there. How did so many people get this so wrong? Three reasons: 1) the study is published behind a paywall, with only the abstract freely available. 2) the methodology sets out to create work relevant to a hyper-specific audience, not the public. And 3) the dataset studied is almost absurdly limited and doesn’t bear (get it?!) comparison to wider information. Let’s work through all three. The Problem is Money I understand the irony, since I’m writing about this on a subscription-model newsletter, but information wants to be free. The study is published by The Wildlife Society and costs $16 to access. Reprinting it is specifically prohibited by the terms of use, so I can only share snippets and my conclusions with you here. Having worked as a journalist for 24 years, I can report with some authority that journalists are both lazy and cheap. I don’t think it’s a stretch to say that much of the material you’re seeing written about this study is drawn from the freely-available abstract (above) only, and not a deep dive into its methodology or data. And that’s a problem, because abstracts are where researchers are able to break from their numbers and editorialize their opinions about conclusions. So what’s getting reported isn’t based on numbers, it’s based on an opinion designed for a specific audience, not the general public. Hell yeah ladies, kick that bear’s ass. The Methodology is Designed to Support a Predetermined Conclusion One of the biggest issues with the science that everyone likes to cite about bear spray’s efficacy is that no one understands that study was designed for a specific audience, looking for a specific answer. And since that audience is not the public, and our safety was not the question being asked, its conclusion is rendered irrelevant to our needs. Yes, I’m talking about Efficacy of Bear Deterrent Spray in Alaska, which was created by Tom Smith and Stephen Herrero, two of the same scientists who put together this dog-bear conflict analysis. In the spray study, the purpose was to present relevant agencies with the information they needed to issue their field workers with bear spray. As such, incidents where people were unable to access the spray or similarly failed to get it deployed in time were excluded from the results, and only incidents they deemed successful were included. Could a ranger roll down their vehicle’s window and scare a bear away from a dumpster by spraying it? Turns out the answer was yes, and that was good enough for the purposes of that study. The sample size of actual bear attacks—the thing you and I would want bear spray to provide a solution to, was too small to draw conclusions from, and didn’t indicate success in that role. Is a Dog a Help or Hindrance in Bear Country? has similar limitations. “Insights provided here are intended to help wildlife managers create effective guidelines regarding the presence of domestic dogs in bear habitat,” is explained clearly by the study’s text. To conduct the study, Smith and Herrero went looking for publicly available reports of dog-bear conflicts: “All incidents included in our analysis involved at least one bear, one dog, and one person who was at immediate risk of injury (e.g., not in a protective structure such as a cabin or vehicle), injured, or killed,” explains the report’s methodology. Why is that a problem? “We recognize that data used in this study are biased in that people generally only report adverse interactions with bears, not benign ones. Consequently, we assume that for the most part, people and their dogs pass through bear country without incident.” As was the problem with the bear spray study, people are drawing conclusions here from a study that was never intended to be relevant to the general public. The Smith-Herrero database famously excludes Alaska’s Defense of Life and Property records, which are elsewhere considered the largest and most authoritative source on human-bear conflict. The Dataset is Absurdly Limited A 2009 study conducted by the Washington Department of Fish & Wildlife estimates that each year there are at least 43,000 documented complaints of human-bear conflict across North America. Is a Dog a Help or Hindrance in Bear Country? Examined those reports for years ranging from 1901 to 2023, and only managed to find 326 such incidents that met the criteria explained above. Let’s do some quick math, poorly. 43,000 incidents x 122 years = 5,246,000 total incidents of documented human-bear conflict. Smith and Herrero were only able to find 326 incidents that met their criteria for dog+human+bear+risk or occurrence of injury. That means there’s a 0.006 percent chance that the study’s conclusion—that dogs make bear encounters more dangerous—even gets a chance of occurring. And remember, that’s only in documented conflicts. There’s no way to know how many people across North America run into a bear in any given year without any conflict, but it’s probably safe to assume that the total number is well in excess of 43,000. And, dig deeper into the study and you can find further restrictions that skew its conclusions even more. “While the people involved in these incidents did not report the level of training their dogs had received, it is our assumption that most were untrained companion dogs as opposed to well-trained bear dogs, such as Karelians and livestock guardian breeds that have proven to be significant aids in bear country,” the study’s methodology explains. And that’s a problem, because an ongoing study here in Montana is finding that the simple presence of a Kangal like our youngest dog Teddy can reduce visits to private property from grizzly bears by 87.8 percent. In addition to being a badass, Teddy is also a companion animal. And in my admittedly limited sample size of the three dogs currently present in our living room, she’s no more effective than her mutt brothers. Plenty of people own a dog capable of deterring bears, even if they didn’t set out to own a bear dog. The real purpose of this study appears to be a recommendation that leashes are mandated and recreationists pursue training in their deterrent of choice. But that doesn’t make for sensational headlines. Are There Any Real Takeaways Here? Let’s throw some numbers around, just to try and get our hands around what the larger picture might look like for bears and dogs here. The American Veterinary Medical Association estimates that 42.6 percent of American households own a dog. The Canadian Animal Health Institute says roughly 35 percent of households in Canuckistan own a dog. In an attempt to create the worst possible result for dogs, let’s run with that 35 percent number. And given that outdoorsy and rural people are more likely to both own a dog, and have bear encounters, let’s just make a giant assumption and apply that number to those 43,000 conflicts documented annually. If 35 percent of 43,000 human-bear encounters involve a dog, then we can assume that at least 15,050 dog-bear conflicts are occurring annually in North America. 15,050 x 122 = 1,836,100. Smith and Herrero were only able to find 326 incidents that met their human, dog, chance or occurrence of injury criteria across 122 years. And only 170 documented human injuries. So, with all the obvious caveats about these numbers in no way describing reality beyond narrow study parameters, what they actually found is that your risk of injury if your dog tangles with a bear is only 0.009 percent. I’ll take those odds next time I’m hiking my dogs in bear country. Top photo: “Superintendent Horace Albright, eating pancakes with bears, at Lake Lodge, Yellowstone National Park.” NPS. A journalist with more than two decades of experience working around the world, Wes Siler is here to cut through the outrage and disinformation to bring you the factual, insightful, actionable reporting you need to understand what’s going on. Upgrading to a paid subscription supports this reporting, and buys personal access to Wes, who will help you save money on gear, plan outdoor adventures, and prepare for real life, and who promises he’s less salty in real life than he sometimes comes across as on the Internet. Wes Siler’s Newsletter is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe

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Aug 27 • 6:47 PM EDT • Science • wessiler.substack.com
“High-Deductible Health Plans Are Not the Answer”

In a new study, LDI Fellows found that high-deductible plans reduce health care spending at first, but may not slow spending growth over time.

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Aug 27 • 11:37 AM EDT • Health • ldi.upenn.edu
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Greenland research institutions halt new US collaborations citing mistrust

Although US President Donald Trump still harbours ambitions to take over Greenland, for US researchers his actions seem to have had the opposite effect. Over the summer, Greenland’s two largest research institutions, the Greenland Institute of Natural Resources and the University of Greenland, both announced policies of not starting new research projects with US researchers.Both institutions cite a mistrust of the US as a motivation for the decision. At the University of Greenland, the change of policy has already led to the rejection of specific proposals for new collaborations, rector Mari Kleist told Science|Business. “The reason is the changed political situation between the US and Kalaallit Nunaat [Greenland], and the uncertainty that the American interest in Kalaallit Nunaat has created,” she said.For the Greenland Institute of Natural Resources, a partially state-funded environmental research institution, the decision was also prompted by a lack of trust in US intentions. In a July interview with local broadcaster KNR, director Josephine Nymand cited concerns about data ownership, US “influence operatives” and social media monitoring of researchers entering the US.The Greenland Institute of Natural Resources has long collaborated with the US National Science Foundation (NSF). The policy change will not affect these existing partnerships but will apply to collaborations with new, “unknown” partners, Nymand said. At the University of Greenland, the policy is the same.The changes come amid proposals of severe cuts to the NSF, which would likely also see the US research presence in Greenland reduced. In spite of this, when asked about the Greenlandic policy change, the NSF remained optimistic of its continued presence in Greenland.“We are grateful to our partners in Greenland for their collaboration in advancing scientific knowledge and training the next generation of researchers. NSF remains committed to the long-term collaborations with Greenland that enable scientific research near communities and on Greenland’s ice sheet,” an NSF spokesperson told Science|Business.Fewer US researchers in GreenlandMost research published on Greenland is on natural science topics such as the cryosphere, ice dynamics, permafrost and climate change. In recent years, US researchers have been the most prolific publishers on Greenland.The US research presence in Greenland goes far beyond the capital of Nuuk, where the two research institutions are located. It includes the Pituffik Space Base in northwest Greenland, various projects in settlements and research stations along the coast, as well as research stations on the Greenland ice sheet itself.The largest of these sites, Summit Station, is located at the highest point of the Greenland ice sheet, about 3,200 metres above sea level, and since the 1980s it has been used for drilling cores out of the ice sheet. These ice cores provide valuable information on the global climate going back at least 100,000 years. About 30 kilometres from Summit Station, the Danish-led Greenland Ice-core Project (Grip), funded by the European Research Council, is also drilling ice cores. Although they initially competed, the relationship between the two research teams has “long been amiable,” Jørgen Peder Steffensen, a Danish researcher who has been part of Grip for more than 40 years, told Science|Business.However, since Trump took office in early 2025, Steffensen has noticed a reduction in US research in the country. “Several of our American partners did not make it into the field this year. Their field seasons were cancelled because they lacked the budget,” he said.He ascribed part of the reduction in US researchers to a renovation of Summit Station. “A very large share of NSF funding has gone into renewing the station. Money has been taken from research and allocated to rebuilding it,” he said.A report published in August by Arctic Hub confirms Steffensen's observations of fewer US researchers. It shows that US research publications on Greenland took a dip towards the end of the period spanning 2015 to 2024. In 2024, before Trump took office, the number of publications had fallen from an average of about 250 articles a year, to just 164, second behind Canada at 169.Data from the NSF logistics provider Battelle also shows a reduction in US research presence in Greenland in recent years. In 2023, Battelle counted 48 projects across 78 locations, but in 2025 that number had fallen to 40 projects across 38 locations. And while relations with US personnel in Greenland have remained strong, some tensions have arisen since Trump took office. “On a personal level, there is nothing. But it’s hanging in the air. It hangs unspoken,” Steffensen said.Cutting ties with US researchers entirely would come at a higher cost for the ice core researchers than the Nuuk-based institutions. To get cargo to and from their bases, both Grip and Summit Station rely on unique, ski-equipped Hercules LC-130 aircraft operated by the New York Air National Guard. Without these, maintaining a research base on the Greenland ice sheet would not be viable on current budgets, Steffensen said. “[If the Hercules planes were not available], we would have to think outside of the box. We would have to use smaller planes, and we would have to build a base closer to the coast. But staying in our current location would be too expensive and it would create a huge carbon footprint,” he said.Suspicious people in NuukIn her explanation of the severed US ties, Greenland Institute of Natural Resources director Josephine Nymand compared the decision to past situations when the institute had to cut ties with China and Russia, the latter due to Russia’s full-scale invasion of Ukraine in 2022. And although the current situation is less severe, the comparison reflects the seriousness with which Nuuk sees the US threats. “From Greenland’s perspective, the US may not look so different from Russia right now: a much larger neighbouring power threatening to invade,” Lin Alexandra Mortensgaard, a researcher of international politics in the Arctic at the Danish Institute for International Studies, told Science|Business. “From a European perspective, it is not a comparable situation, because we are entangled with the US on all possible fronts and do not want to destroy more than is absolutely necessary. But from Greenland’s side, there may well be a need to send a clear signal to the US,” she went on. Suspicions have been fuelled by instances of Trump-affiliated people in Greenland trying to persuade Greenlandic citizens to support a US takeover. The most prolific among them is Tom Dans, a former venture capitalist and pecan farmer who was appointed by Trump as the chair of the United States Arctic Research Commission. Observers fear that he is now using research to achieve a US takeover.“Greenland is a small society with a small population, so when Americans with unclear affiliations wander around, trying to be good friends with people, and you don't know what they want, that creates mistrust. This probably played into the research institutions taking these drastic steps,” Mortensgaard said.Related articles:The US ‘golden age’ science strategy: what Europeans need to knowEU polar research melts into the backgroundAnchor Greenlanders in Arctic climate research, experts tell EU ahead of policy updateAnd although Greenland’s population is small at just 57,000, for Mortensgaard, it serves as a microcosm for the geopolitical situation as a whole: global powers fighting for their interests to the detriment of the common interest. Arctic research already suffered when collaborations with Russia broke down in 2022, she said, so a split with the US would be a serious hit to climate science.“The Arctic climate system does not respect borders or geopolitical divides. When collaboration across those lines suddenly becomes impossible, it is a huge problem for knowledge production,” she said. European alternatives?The Greenland Institute of Natural Resources is funded partly by research grants from external sources like the NSF. To replace the US funding, the institute will have to look for alternative revenue sources, and Nymand said that she is looking to Europe for those. Aside from Denmark, of which Greenland is formally a part, she also noted increased interest in research collaborations from the UK, France and Switzerland. Kleist of the University of Greenland told Science|Business that it was too early to say if the severed US ties would lead to more collaborations with Europe. Meanwhile, Mortensgaard believed that the tensions in Arctic research could well leave room for closer European partnerships, or stronger links with Canada. “I spoke to Canadian researchers who had long-standing relationships with American colleagues and who collaborated with the US Navy, but who had gotten worried that their data on sea ice could be used if Trump suddenly decided to follow through on his threats of invading,” she said. “Like Canada, I think Greenland is considering creating closer ties to Europe and I think European capitals will be open to this,” she said.

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Aug 27 • 8:00 AM EDT • Science • sciencebusiness.net
Dolly Parton struggled with kidney stones for years. Here are the warning signs to know

Dolly Parton’s death is bringing new attention to her history of recurring kidney stones. A Duke Health urologist explains when kidney stones can become life-threatening, their potential connection to other health conditions, and how to reduce the risk of recurrence.

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Aug 26 • 3:28 PM EDT • Health • wral.com
Google Play mandating reduced memory usage & seamless device migration in 2027

In response to “hardware supply constraints that are altering device memory,” Google aims to reduce the memory usage of Android apps.

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Aug 26 • 2:32 PM EDT • Technology • 9to5google.com
Sonoma County breaks ground on new behavioral health facility for teens, young adults

Sonoma County crews were beginning work this week on a new mental health and substance use disorder facility for local youth, advancing a project meant to reduce reliance on out-of-county facilities.

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Aug 26 • 1:27 PM EDT • Health • pressdemocrat.com
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Mental Health Benefits of Travel: How Vacations Reduce Stress

Forget the staycation. Research reveals that travel can build stress resilience, sharpen cognitive health and ward off depression far better than staying home.

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Aug 26 • 10:49 AM EDT • Health • wsj.com
Scientists may have found a shortcut to calorie restriction’s anti-aging benefits

Moderate calorie restriction lowered an immune protein called C3 that appears to help drive chronic inflammation as the body ages. Blocking the same protein reduced age related inflammation in mice, raising the possibility that future treatments could mimic some benefits of calorie restriction without severe dieting.

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Aug 26 • 8:00 AM EDT • Science • sciencedaily.com
Court blocks Trump push to strip grant funds from King County

The majority wrote that federal agencies' arguments for the changes are "fairly reduceable to the excuse 'the President made us do this.'"

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Aug 25 • 8:21 PM EDT • Politics • seattletimes.com
Turmeric compound may protect blood vessels from diabetes damage

A compound found in turmeric may help protect blood vessels from some of the damage caused by Type 1 diabetes. In rats, curcumin reduced inflammation, improved cellular signaling, and restored vascular health to levels resembling those of nondiabetic animals. The results hint at a possible new way to reduce the long-term cardiovascular risks of diabetes, but human trials are still needed.

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Aug 25 • 8:00 PM EDT • Science • sciencedaily.com
AI helps design new materials that work in the real world

MIT researchers added a new component to AI models that design new materials, helping ensure the material will be stable and practical for real-world use. The “CrysVCD” approach could reduce the money and time spent on screening out unusable designs.

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Aug 25 • 8:00 PM EDT • Science • news.mit.edu
Tisdel stands with Michigan voters to get money out of politics

State Rep. Mark Tisdel today voted to reduce the influence of powerful special interests in Michigan politics and strengthen public confidence that decisions in Lansing are made on behalf of taxpayers, patients and ratepayers, not major corporations seeking political influence. “The people of Michigan have been clear: They want money out of politics and accountability […]

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Aug 25 • 4:47 PM EDT • Politics • gophouse.org
Nevada sues Trump administration over Colorado River cuts

The state of Nevada on Monday filed a lawsuit against the Trump administration and Interior Secretary Doug Burgum, seeking to block the Colorado River management plan. On Friday, Burgum released a “record of decision” that would reduce water allocations to California, Nevada and Arizona, the Lower Basin states of the Colorado River. The record of […]

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Aug 24 • 1:36 PM EDT • Politics • coloradopolitics.com
‘We can’t accept falling behind’: Roger Denny addresses OU’s ‘Palace Project,’ stadium seat reduction

After OU announced plans last November to reduce Gaylord Family Oklahoma Memorial Stadium’s capacity by roughly 7,000 seats, athletic director Roger Denny provided new details on Aug. 20 on the

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Aug 24 • 12:29 PM EDT • Sports • oudaily.com
Stony Brook Southampton Hosts Falls Prevention Program to Support Healthy Aging

Stony Brook University will offer its S.A.F.E. (Strength, Awareness, Function, Education) Falls Prevention Program, a free eight-week workshop designed to help older adults improve balance and strength, reduce their risk of falls and maintain independence in their daily activities. Held at Stony Brook Southampton, the program provides older adults on the East End with practical

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Aug 24 • 9:00 AM EDT • Health • sbmatters.stonybrook.edu
Bird flu is spreading. Your backyard feeder could make it worse

Backyard bird feeders could become unexpected hotspots for H5N1 as Australia’s bird flu outbreak spreads, bringing species together in ways that rarely occur naturally. Experts say stopping feeding is safest, while smaller amounts of food, no hand-feeding, and careful cleaning can reduce the danger.

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Aug 24 • 8:00 AM EDT • Science • sciencedaily.com
Mozambique strengthens regulation of medicines and imported vaccines, boosting health protection

Mozambique has reached a major milestone in strengthening the regulation of medicines and imported vaccines, with its national regulatory authority recognized by the World Health Organization (WHO) as having a stable, well-functioning and integrated regulatory system.The Autoridade Nacional Reguladora de Medicamentos de Moçambique (ANARME) has achieved Maturity Level 3 (ML3) for the regulation of medicines and imported vaccines under WHO’s global classification of national regulatory authorities.Mozambique becomes the 10th country in Africa to reach ML3, joining Egypt, Ethiopia, Ghana, Nigeria, Rwanda, Senegal, South Africa, Tanzania and Zimbabwe and marking further momentum in strengthening regulatory systems across the region.For people in Mozambique, stronger regulation means greater assurance that medicines and vaccines are appropriately evaluated for quality, safety and efficacy and monitored throughout their lifecycle. It also strengthens the country’s ability to identify and respond to safety concerns and substandard or falsified products, while supporting timely access to quality-assured health products.“Mozambique’s achievement is the result of sustained investment in regulatory capacity that will deliver crucial benefits for public health,” said Dr Sylvie Briand, WHO Chief Scientist and Assistant Director-General a.i. for Health Systems, Access and Data. “Strong regulatory systems protect people, build confidence in health products and help countries respond more effectively to evolving public health needs and challenges. Mozambique’s progress also contributes to advancing regulatory capacity across Africa and promoting more equitable access to safe and quality-assured medicines and vaccines.”Building a stronger regulatory systemMozambique’s achievement follows years of sustained efforts to build the institutions and capabilities needed for effective regulation.WHO worked closely with ANARME throughout this process, assessing the national regulatory system and supporting the authority in addressing identified gaps and strengthening priority areas.WHO evaluates national regulatory systems using its Global Benchmarking Tool (GBT), which assesses the regulatory functions required to ensure the quality, safety and efficacy of medical products. These include registration and marketing authorization, licensing, market surveillance and control, pharmacovigilance, regulatory inspection, laboratory testing and oversight of clinical trials, as applicable. WHO’s maturity levels range from 1 to 4. Reaching ML3 confirms a stable, well-functioning and integrated regulatory system, while ML4 represents an advanced system focused on continuous improvement.Benefits for Mozambique and the African continentAn ML3 regulatory system can support more timely and predictable regulatory decisions, reinforce safety monitoring and help ensure that health products entering and remaining on the market meet appropriate standards.It also creates greater opportunities for regulatory cooperation and reliance – approaches that help authorities make use of the work and decisions of trusted regulators, reduce unnecessary duplication and allocate limited resources more efficiently, while maintaining rigorous standards for quality, safety and efficacy.As the first Portuguese-speaking country in Africa to reach ML3, Mozambique’s experience can also contribute to strengthening regulatory systems and fostering greater cooperation, knowledge sharing and reliance among Portuguese-speaking countries and across the African continent. Its achievement further reinforces a more connected African regulatory ecosystem, providing a solid foundation on which the newly established African Medicines Agency can build to advance regulatory convergence and cooperation across the region.Strengthening confidence in regulatory recognitionMozambique’s achievement comes as WHO strengthens the process through which the performance of national regulatory systems is recognized.The newly established Technical Advisory Group on Regulatory Systems Strengthening (TAG-RSS) brings together independent international experts to advise WHO on whether recommendations concerning regulatory authorities reaching ML3 and ML4 and WHO-Listed Authorities, are supported by the findings of WHO evaluation processes. Its recommendations provide an additional level of independent assurance, strengthening the impartiality, transparency and credibility of WHO’s recognition process.Mozambique is among the first countries to achieve ML3 following consideration and recommendation by the TAG-RSS. As part of the same TAG-RSS process, South Africa was recommended to retain its ML3 status for the regulation of vaccines manufactured, imported or distributed in the country, following an additional WHO assessment. This extends the recognition first granted in 2022 and underscores the sustained performance of the South African Health Products Regulatory Authority (SAHPRA).The two recognitions highlight continued progress in strengthening regulatory systems across Africa, as well as the importance of continued performance, improvement and assessment in sustaining regulatory maturity.WHO will continue working with ANARME and SAHPRA to sustain these gains and support continuous improvement as science, technologies and public health needs evolve.

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Aug 24 • 8:00 AM EDT • Health • who.int
The New Shokz OpenFit Air 2 Earbuds Are Nearly 20 Percent Lighter Than The Previous Generation

They feature an open-ear design that reduces pressure and heat buildup.

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Aug 24 • 7:00 AM EDT • Technology • engadget.com
Xiaomi launches new Xring chip, partners with TSMC for production, sources say

Chinese smartphone maker Xiaomi on Monday unveiled a new version of its in-house Xring smartphone processor, betting that deeper control over key components will help ​strengthen its supply chain and reduce reliance on external chip ​suppliers.

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Aug 24 • 2:22 AM EDT • Technology • reuters.com
Eastlake science students make district history

Three Eastlake High School students made Sweetwater Union High School District history this year when they became the first students from the district to qualify for the International Science and Engineering Fair, an international competition that brings together some of the top high school researchers from around the world. Ronald Wyatt, Giles Del Priore and Ihan Sung advanced to the competition after successful runs at regional and state science fairs. Sung went a step further, placing fourth in the chemistry category at ISEF. The students were recognized on Aug. 10 during a Sweetwater Union High School District board meeting at the district office in Chula Vista.For Wyatt and Del Priore, recent Eastlake graduates, the journey began with a shared concern about dementia and the challenges faced by families caring for loved ones with memory impairment. Their engineering project, “Design and Evaluation of a Behaviorally Grounded Caregiver-Governed AI Companion for Individuals with Memory Impairment,” earned the Sweepstakes Award at the Sweetwater District STEM Fair and first place in its division at the Greater San Diego Science and Engineering Fair. The project explored whether Artificial Intelligence could provide companionship and support while helping reduce stress for people with dementia and their caregivers. “Our inspiration came from personal experience. Both of us have seen family members and loved ones affected by dementia, and we’ve witnessed how overwhelming the caregiving process can be,” Wyatt said. Del Priore said the students also wanted to address the high cost of third-party health care services while creating something that could potentially help their own families as well as people elsewhere. The students developed an AI system designed with safeguards intended to prevent misinformation reinforcement, emotional escalation and unsafe responses. In 240 controlled trials involving memory, identity, agitation and neutral scenarios, they said the system consistently prevented harmful incorrect reinforcement while using context-aware silence, de-escalation and caregiver verification. The project required the students to combine Artificial Intelligence, psychology, neuroscience and human-computer interaction. For Del Priore, one of the biggest technical challenges was getting the AI companion to communicate verbally with a patient. Hardware limitations required the students to collaborate with multiple Python libraries for speech-to-text and text-to-speech functions while keeping the cost of the companion low. “For us, the biggest challenge was translating complex behavioral and cognitive care principles into a functioning AI system,” Wyatt said.Qualifying for ISEF was a milestone that student expected. The international competition proved to be another milestone. “Competing at ISEF was an incredible experience and unlike anything we’ve ever done before,” Del Priore said. “Being surrounded by some of the most talented young researchers from around the world was both inspiring and motivating.” He said the experience stood out because of the emphasis on collaboration, innovation and scientific discovery. “The most memorable part was seeing how people from completely different backgrounds and disciplines approached solving real-world problems with creativity and passion,” he said. The students also credited teachers and mentors who supported their work. Del Priore said his sophomore-year AP Physics teacher, Dr. Price, was particularly influential. “Through all of my personal and academic struggles, Dr. Price always believed in me,” Del Priore said. “All of his faith in me really molded me into the person I am today and helped create my love for science even through tough times.” Wyatt is continuing his education at UC Santa Cruz, where he plans to study biomolecular engineering and bioinformatics, with an interest in research involving Artificial Intelligence, biology and health care. Del Priore plans to double major in chemistry and accounting. Sung, a rising Eastlake senior, qualified for ISEF after winning first place in the Engineering: Energy, Materials & Transport category at the Greater San Diego Science and Engineering Fair and first place in chemistry at the California Science and Engineering Fair. His project, “Renewable Ammonia Electrochemical Synthesis by Glow Discharge with an Iron-Based Catalyst,” involved a device he designed and engineered to produce renewable ammonia, with potential applications in fertilizer production and energy storage. Sung became interested in the project after considering the relationship between food insecurity and fertilizer costs. His system uses plasma to break apart nitrogen molecules so they can interact with hydrogen and form ammonia. At ISEF, Sung competed against more than 1,700 students from 65 countries and earned fourth place in chemistry. “I am proud to become one of te first students in the district to qualify for ISEF because this milestone can inspire others in the district to attain similar goals,” Sung said.

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Aug 23 • 1:00 PM EDT • Science • thestarnews.com
This is the only budget ergonomic office chair to get a 10/10 review from Creative Bloq, and it's now reduced by 22%

The one cheap office chair we actually wanted to keep is now just $132.53.

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Aug 23 • 10:00 AM EDT • Technology • creativebloq.com
Experimental compound helps burn fat without muscle loss

A decades-old compound may point to a new way of treating obesity by making the body burn more energy rather than simply reducing appetite. In mice, TOFA increased energy use by as much as 18%, reduced body fat without significant muscle loss, and improved blood sugar, triglycerides, and fatty liver disease. It also produced stronger results when combined with GLP-1 drugs such as Ozempic, Wegovy, Mounjaro, and Zepbound.

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Aug 22 • 8:00 PM EDT • Science • sciencedaily.com
Reimagining how scientists study the chemistry of the air

Professor Victoria Barber and doctoral student Cooper Crabtree are spearheading Keck Foundation-funded project charting a path toward better understanding atmospheric oxidation. by Álvaro Castillo, UCLA College of Letters and Science From the vantage point of Victoria Barber, a UCLA assistant professor of chemistry and biochemistry, understanding the chemical reactions that shape air quality and climate are among the most pressing scientific challenges of our time. And thanks to a recent grant from the W.M. Keck Foundation, she and doctoral student Cooper Crabtree will spearhead a new research project exploring exactly how pollutants form in the atmosphere. Specifically, the project will examine how volatile organic compounds transform through atmospheric oxidation and explore how pollutants, like smog, form in the atmosphere. VOCs are released by sources ranging from trees and wildfires to vehicle exhaust pipes and consumer products such as cologne and perfume. As they undergo atmospheric oxidation, they can transform into a wide range of other compounds. Anyone in Southern California can attest to the urgency of this area of research — for example, in late July of this year, Los Angeles County was under an active ozone pollution advisory for almost a full week. While many people associate ozone with the protective ozone layer high in the stratosphere, ground-level or tropospheric ozone is a harmful secondary pollutant formed through atmospheric oxidation. Understanding how VOCs transform into pollutants like ozone is therefore critical to improving air-quality forecasts and informing strategies to reduce exposure. “My group is focused on trying accelerate our understanding of these networks of reactions so that we can do a better job of predicting how those pollutants form,” Barber said. “When we make decisions about how we might alter emissions, we can understand how that’s going to influence the production of these downstream pollutants.” With support from the W. M. Keck Foundation, Barber and Crabtree are developing new experimental approaches that will combine — and improve — techniques to study hundreds of chemical systems more efficiently than traditional methods allow. Instead of spending years decoding a single VOC, the project seeks to dramatically expand the pace and scale of discovery. The grant comes at a particularly important moment for environmental research. Barber, who joined UCLA in 2023, says funding for climate and air-quality research, especially for early career scientists, has become increasingly difficult to secure, a challenge compounded for ambitious projects that require building entirely new research infrastructure. The Keck Foundation’s support, Barber said, provides the flexibility to pursue bold early-stage, high-risk ideas that may be more difficult to fund using conventional federal funding sources. “It’s really, really hard to do environmental research under the current federal paradigm,” Barber said. “By stepping in and providing stable and flexible funding to explore this new idea, the Keck Foundation is making a huge difference to my research program.” In addition to funding early-career faculty, the Keck Foundation’s support is also focused on empowering graduate students like Crabtree in their scientific growth. The project gives Crabtree the opportunity to help develop an entirely new experimental approach to studying atmospheric chemistry — an experience that will provide him with valuable technical skills, scientific training and preparation for the next stage of his career. Stable funding also allows doctoral students like Crabtree to devote themselves more fully to research rather than balancing their scientific work with additional teaching responsibilities needed to cover funding gaps. “Getting to devote more of my time to research this past school year has greatly improved the pace and quality of our experiments, data analysis and planning for our future work,” said Crabtree, who is pursuing a Ph.D. in chemistry. “I feel very lucky — especially amid the current uncertainty surrounding scientific funding — to be able to continue exploring exciting knowledge gaps in our field and growing as a scientific researcher.” For Barber, mentorship is among the most rewarding and important aspects of her role as a faculty member. “Our jobs as faculty are to do good science and make good scientists,” she said. “I believe the Keck Foundation shares this belief and sees the potential positive impact this project can have.”

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Aug 21 • 3:28 PM EDT • Science • chemistry.ucla.edu
Community Invited to Forest Health and Wildfire Risk Town Hall on Aug. 27

Nevada County community members are invited to attend the “Hard Choices in the Woods: Forests, Fire and Herbicide” Town Hall on forest health and vegetation management tools used to reduce

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Aug 21 • 1:48 PM EDT • Health • nevadacountyca.gov
US service sector fuels acceleration in business activity, S&P Global says

The strongest growth in the U.S. ​services sector in nearly two years powered a sharp acceleration in overall business activity in August, offsetting a ‌slowing of growth in a manufacturing sector being restrained by reduced stock building and supply disruptions from the U.S.-led war with Iran.

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Aug 21 • 9:48 AM EDT • Business • reuters.com
Why scientists are stoked about mysterious black hole stars

You've heard of black holes. You've heard of stars. But have you heard of the newly discovered black hole stars that may explain multiple mysteries of the universe? We just did and we're honestly freaking out about it. Learn everything you need to know about it in this episode. Plus, hear some other cool stories fresh off the presses: Which exercise can help reduce your risk of dementia and how shrews shrink — and then regrow — parts of their body throughout the year.Interested in hearing more reporting on space, scientific mysteries or other emerging science? We want to know! Email us what you'd like us to talk about at shortwave@npr.org!Support public media with NPR+ and enjoy perks for over 25 podcasts like this one. This show’s perks include sponsor-free listening. Learn more at plus.npr.org.

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Aug 21 • 3:00 AM EDT • Science • npr.org
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What happens to people’s health when air pollution is reduced?

Growing evidence that cutting coal use and bans on high-polluting vehicles are leading directly to health benefits

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Aug 21 • 1:00 AM EDT • Health • theguardian.com
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How Scientists Are Fighting Food Waste with Phages, Silk, and More

From smart packages to bio-based coatings, researchers innovate on ways to reduce food contamination and extend produce shelf life, aiming to curb global food loss.

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Aug 21 • 12:00 AM EDT • Science • the-scientist.com
Ormond-by-the-Sea restaurant says A1A construction is hurting business

A Volusia County restaurant says an ongoing road construction project has sharply reduced its parking and is hurting business, while state transportation officials say the changes are intended to improve safety for drivers and pedestrians.

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Aug 20 • 8:48 PM EDT • Business • fox35orlando.com
SBA wants to give 114,000 more companies access to small business contracts

SBA is proposing to reduce the number of and simplify the approach to the NAICS codes and reduce the total size standard categories from nearly 1,000 to 338.

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Aug 20 • 6:22 PM EDT • Business • federalnewsnetwork.com
Turning Play into Progress: An Update on Sustainability Efforts

Learn how Sony Interactive Entertainment is advancing sustainability through lower emissions, reduced plastic packaging, ecosystem restoration, and climate research.

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Aug 20 • 9:00 AM EDT • Entertainment • sonyinteractive.com
Best Way To Reduce Heart Disease Risk Is Getting This 1 Health Factor Under Control, Doctor Says

In TODAY.com’s Expert Tip of the Day, a doctor reveals “the most important modifiable risk factor for heart disease” and how to get it to a healthy level if it’s too high.

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Aug 20 • 8:00 AM EDT • Health • today.com
I'm a former surgeon general. Kennedy shouldn't give disease 'a break.'

Outbreaks are rising. Response capacity is reduced. And HHS Secretary RFK Jr. holds a unique authority – and responsibility – to act.

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Aug 20 • 6:04 AM EDT • Health • usatoday.com
Cancer doctor reveals 5 habits that may reduce disease risk and improve outcomes

A breast surgical oncologist shares five everyday strategies to reduce cancer risk, including how GLP-1 drugs like Ozempic could play a role.

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Aug 19 • 9:48 PM EDT • Health • foxnews.com
Knee osteoarthritis isn’t inevitable — here’s what you can do

Knee osteoarthritis can seriously affect mobility and quality of life, but its progression isn’t completely out of your control. Exercise, stronger leg muscles, a healthier diet, and even modest weight loss can dramatically reduce stress on the knees and help keep pain in check.

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Aug 19 • 8:00 PM EDT • Science • sciencedaily.com
Coe College announces approval of three-year online business administration degree

Coe College has received approval from the Higher Learning Commission to launch a three-year, reduced-credit bachelor’s degree in business administration with a concentration in strategic leadership, the college announced Aug. 18. The online-only program is designed for adult students and working professionals. College officials said it is a true three-year degree, rather than an accelerated […]

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Aug 19 • 4:26 PM EDT • Business • corridorbusiness.com
Coe College to launch reduced-credit business administration degree program

Coe College will offer a new online, reduced-credit bachelor's degree program in business administration starting this fall.

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Aug 19 • 10:03 AM EDT • Business • iowacapitaldispatch.com
No Neutral Number: The Politics of Defining and Measuring Inequality

Before anyone can reduce inequality, someone has to define it, decide how to measure it, and choose how to respond.

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Aug 18 • 12:29 PM EDT • Politics • cic.nyu.edu
Douglas County, Colorado launches plan to cut red tape, speed up business development

Douglas County leaders have launched an initiative to reduce red tape and incentivize business development in the county.

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Aug 18 • 12:03 AM EDT • Business • cbsnews.com
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Dartmouth Health says it needs to close telehealth services for emergency and intensive care

Five Vermont hospitals rely on the remote care to reduce costs of specialists and transfers while still providing high-acuity care close to home. Dartmouth Health says the costs are “simply unsustainable.”

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Aug 17 • 11:18 AM EDT • Health • vtdigger.org
Hospitals say they found a tool to help reduce childbirth risks: wristbands

Hospitals across the U.S. are trying to reduce maternal deaths and complications after pregnancies using one small tool: a silicone wristband stamped with the declaration “I Gave Birth.”

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Aug 17 • 7:00 AM EDT • Health • cnn.com
Could a drug designed for weight loss help athletes perform better?

GLP-1 weight-loss drugs can reduce weight and improve health, but could they also boost athletic performance?

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Aug 17 • 5:35 AM EDT • Health • bbc.com
5 small-business ideas for introverts

Prefer going solo? These jobs let you focus on creativity and deep work—and reduce meetings.

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Aug 17 • 4:00 AM EDT • Business • fastcompany.com
Sports leagues’ concussion guidelines must be broadened as brain health concerns rise

Many sporting leagues are trying to reduce concussion risk, but their policies mainly fail to mention a growing threat.

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Aug 16 • 9:48 PM EDT • Health • theconversation.com
Sports leagues’ concussion guidelines must be broadened as brain health concerns rise

Many sporting leagues are trying to reduce concussion risk, but their policies mainly fail to mention a growing threat.

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Aug 16 • 9:48 PM EDT • Sports • theconversation.com
Trump orders military to ‘substantially reduce’ joint exercises with South Korea

The announcement comes as Trump said South Korea declined to help denuclearize Iran.

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Aug 16 • 7:16 PM EDT • Politics • nbcnews.com
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Trump reduces military exercises with South Korea, citing good ties with Kim Jong Un

The president cited the cost of the drills and said he did not want to send a signal that is "totally inappropriate and hostile" to North Korea. He also criticized South Korea for not helping him on Iran.

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Aug 16 • 6:52 PM EDT • Politics • washingtonpost.com
What Three Encompass Health Insiders Selling Signals After a Rate Increase

This sale reduced an insider's direct equity holdings by 11%.

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Aug 16 • 3:33 PM EDT • Health • finance.yahoo.com
This 10-cent heart drug cuts hospitalizations by 25%

A centuries-old heart drug costing less than ten cents a day could help keep heart-failure patients out of the hospital. New research suggests low-dose digoxin can reduce heart-failure hospitalizations by about 25%, potentially paving the way for its return as a major treatment.

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Aug 16 • 8:00 AM EDT • Science • sciencedaily.com
iPhone 18 Pro Pricing: Can Apple Protect Its Profit Margins?

Facing higher memory and storage costs for the iPhone 18 Pro, Apple has several options to reduce the price rises while increasing the average revenue per user.

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Aug 15 • 7:27 PM EDT • Technology • forbes.com
Scientists solve the mystery of a brain “switch” that can trigger weight loss in opposite ways

Scientists have uncovered why two seemingly opposite ways of targeting the same brain receptor can both promote weight loss. In mice, activating the GIP receptor in the brainstem reduced appetite, while blocking it in the hypothalamus removed a kind of “brake” on fullness signals. The discovery helps explain why very different obesity drugs can achieve similar results and suggests that carefully combining GIP-targeting treatments with GLP-1 drugs like those related to Wegovy and Ozempic could produce stronger effects.

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Aug 14 • 8:00 PM EDT • Science • sciencedaily.com
American Express Expands Virtual Cards for Corporate and Business Travel Spending

American Express is expanding the availability of virtual cards for businesses, as more companies use digital payments to manage expenses and reduce

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Aug 13 • 11:51 AM EDT • Business • pymnts.com
A City Mobilizes Against a Stubborn Health Threat: Mosquitoes

The city of Belém in northern Brazil was overwhelmed by an outbreak of dengue two years ago. An all-out municipal effort has reduced cases and may offer lessons to American cities.

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Aug 13 • 10:49 AM EDT • Health • nytimes.com
A Public Health Approach: Using Alcohol Regulation Strategies to Reduce Online Sports Betting Harms in Higher Education

The O’Neill Institute believes that the law is a fundamental tool for solving critical health problems.

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Aug 13 • 10:10 AM EDT • Sports • oneill.law.georgetown.edu
Common Health Coalition secures $100M from OpenAI Foundation to boost hepatitis C cure rates

The OpenAI Foundation invested $100 million towards a new public health initiative with the Common Health Coalition aimed at helping states and local jurisdictions close discovery-to-delivery gaps, | Funding will support the deployment of AI-enabled tools to help identify patients who have fallen out of care, reduce administrative burden, strengthen care coordination and improve patient outcomes.

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Aug 13 • 5:00 AM EDT • Health • fiercehealthcare.com
From first 72 hours to first 90 days, tech extends hospital care beyond discharge

As value-based care expands, health systems are using technology-dependent transitional care to support patients at home, reduce readmissions and improve outcomes.

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Aug 12 • 10:28 AM EDT • Health • healthcareitnews.com
Ozempic may have revealed the brain’s hidden “craving center”

Ozempic-like drugs appear to weaken more than hunger—they may also reduce cravings for alcohol and other addictive substances. Scientists are increasingly tracing this effect to the lateral septum, a brain region that helps connect memories and surroundings with rewarding experiences. Packed with GLP-1 receptors, it may act as a crucial control point between thinking about a reward and feeling compelled to pursue it. The discovery could open new approaches to treating addiction as well as obesity.

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Aug 12 • 8:00 AM EDT • Science • sciencedaily.com
Scientists turn Starlink into a giant scanner for Earth’s upper atmosphere

Researchers have found a clever new way to map a part of Earth’s upper atmosphere that is notoriously difficult to observe. Using orbital data from roughly 1,200 Starlink satellites, they reconstructed changes in atmospheric density about 500 kilometers above Earth. The approach could sharpen satellite tracking and help reduce the growing risk of collisions in increasingly crowded orbits.

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Aug 12 • 8:00 AM EDT • Science • sciencedaily.com
An Overview of State-Directed Payments and Medicaid Provider Taxes: History and Potential Effects of the Working Families and Tax Cut Legislation on Health Care Costs

Health care provider taxes and state-directed payment policies in the Working Families and Tax Cut legislation are expected to reduce non-Medicaid prices by up to 3.5 percent in markets with provider taxes and reduce spending on Medicaid, commercial and Medicare coverage. Our spending estimates indicate that there will be an additional $29 billion in federal savings on Medicare and commercial coverage for each $100 billion that federal Medicaid spending is reduced.KEY POINTS

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Aug 12 • 8:00 AM EDT • Health • aspe.hhs.gov
How Many Steps To Walk For Better Mental Health, Per Psychiatrist

In TODAY.com’s Expert Tip of the Day, a psychiatrist offers her simple prescription for improving mental health with walking, which can reduce depression and anxiety.

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Aug 12 • 8:00 AM EDT • Health • today.com
UConn Institute of Sports Medicine: The Science of Motion

The data-driven insights help support recovery, enhance performance, and reduce injury risk

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Aug 12 • 7:30 AM EDT • Science • today.uconn.edu
UConn Institute of Sports Medicine: The Science of Motion

The data-driven insights help support recovery, enhance performance, and reduce injury risk

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Aug 12 • 7:30 AM EDT • Sports • today.uconn.edu
Hospitals Say They Found a Tool To Help Reduce Childbirth Risks: Wristbands

North Carolina and other states have embraced “I Gave Birth” wristbands as a way to encourage women to seek help when they have postpartum complications. They’re gaining steam as the Trump administration’s cuts to Medicaid threaten postpartum care.

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Aug 12 • 5:00 AM EDT • Health • kffhealthnews.org
Your Business Is Probably Your Largest Asset. Are You Managing It That Way?

Your business is likely your largest asset. Learn why managing it for enterprise value—not just income—can increase wealth, reduce risk and create more options.

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Aug 12 • 5:00 AM EDT • Business • forbes.com
Pinellas County increases mosquito control in Palm Harbor following Department of Health-Pinellas Dengue Fever alert

Pinellas County Mosquito Control is ramping up efforts to reduce mosquito populations and urging residents to take actions to protect themselves in...

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Aug 11 • 4:33 PM EDT • Health • pinellas.gov
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Oracle is planning another round of job cuts this month

The potential layoffs reduce Oracle's payroll as it racks up billions in debt to fund AI infrastructure.

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Aug 11 • 4:04 PM EDT • Business • businessinsider.com
Fall sports season is about to begin in Maine: How can you avoid getting hurt?

The fall sports season is about to begin and athletes are getting excited. Injuries are a real part of sports, but there are ways to reduce your risk.

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Aug 11 • 12:42 PM EDT • Sports • wmtw.com
AHA resource: Economic Impact of Disparities in Health Outcomes

The AHA Aug. 11 released a new resource guide designed to address a critical gap by helping leaders understand and quantify the economic burden of disparities of health outcomes. The guide provides practical methods to identify and assess the financial impact of health disparities, along with data-driven approaches to implement interventions that both improve outcomes and reduce costs. READ MORE

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Aug 11 • 11:29 AM EDT • Health • aha.org
Trump Administration Bypasses Science Again, Doubles Down on Restrictions to Childhood Vaccines

WASHINGTON, D.C. – The Trump administration today issued a new executive order directing changes to the federal childhood vaccine schedule that, if fully implemented, would reduce access to life-saving vaccines for children, add new barriers to care, and further degrade the scientific process the federal government has relied on for decades to ensure vaccine access […]

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Aug 11 • 9:33 AM EDT • Science • familiesusa.org
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Health Sciences outreach program helps amplify the voices of people with aphasia

The UK College of Health Sciences is helping people with aphasia reconnect with their communities by partnering with local businesses and organizations to create more communication-friendly spaces. Through a unique outreach program, students work alongside individuals with aphasia to educate employees, reduce communication barriers and make everyday experiences more accessible and welcoming.

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Aug 11 • 3:00 AM EDT • Health • uknow.uky.edu
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Pork producer sees value in AgView health data tracking

Disease prevention remains a key focus for a Michigan pork producer. Joe Dykhuis says he utilizes AgView to make decisions that support herd health and reduce disease spread. “As a producer using AgView, I have already loaded into that system all the locations I have pigs on. We put in any time we move pigs […]

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Aug 10 • 11:47 AM EDT • Health • brownfieldagnews.com
How sports diplomacy is changing how nations connect

Sports diplomacy can strengthen alliances, reduce tension between potential enemies and turn the world’s attention toward regions too frequently ignored.

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Aug 10 • 11:40 AM EDT • Sports • washdiplomat.com
Gen Z calls it ‘loud budgeting’ – small business owners have been doing it for decades

The practice of openly proclaiming to the world what you can’t afford can lead to lower fees, reduced prices and better deals

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Aug 10 • 10:00 AM EDT • Business • theguardian.com
Delaware Implements Collaborative Communication Platform for Heart Health

Learn how Delaware leveraged online tools to improve collaboration between partners working to reduce heart disease in the state.

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Aug 10 • 9:00 AM EDT • Health • astho.org
The rise of managed intelligence: AI is rewriting the cybersecurity playbook

AI adoption is accelerating. Learn why governance, cybersecurity and executive oversight are essential to reduce risk and scale AI safely.

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Aug 10 • 9:00 AM EDT • Business • crainscleveland.com
AbCellera women’s health data top ‘most aggressive upside scenario,’ putting Astellas and Bayer on notice

AbCellera has reported phase 2 results “beyond even the most aggressive upside scenario” that its CEO dared to consider, boosting the biotech’s chances of challenging Astellas and Bayer for a women’s health market. The phase 2 clinical trial compared ABCL635, an antibody targeting NK3R, to placebo in patients with hot flashes caused by menopause. Investigators enrolled 92 postmenopausal women experiencing a mean of about 10 moderate or severe hot flashes per day. By Week 4, the number of moderate or severe hot flashes had fallen by a mean of 8.8 on ABCL635 and by 3.5 on placebo. That statistically significant, placebo-adjusted reduction of 5.3 hit the trial’s primary endpoint. The level of efficacy also cleared the bar set by existing drugs. While cross-trial comparisons can be misleading, AbCellera CEO Carl Hansen, Ph.D., had seen enough to start hyping the program. “We now view ABCL635 as a potential best-in-class non-hormonal therapy with strong differentiation against approved NK3R competitors across all important dimensions, including efficacy, safety, dosing and convenience,” Hansen said on a Monday morning conference call with investors to discuss the data. “We believe ABCL635 is now a highly de-risked program.” Last week, Hansen used AbCellera’s earnings call to set expectations for readout, with the CEO defining success as a clean safety profile and efficacy comparable to the two approved small molecules. The data vaulted over that bar. Astellas linked (PDF) one of the small molecules, Veozah, to placebo-adjusted reductions in hot flash frequency of 2.1 and 2.6 at Week 4 of its two phase 3 trials. Bayer reported (PDF) placebo-adjusted reductions of 3.04 and 3.29 at Week 4 of pivotal studies for its small molecule, Lynkuet. At 5.3, the placebo-adjusted reduction in AbCellera’s trial comfortably cleared the standard set by the incumbents. Veozah and Lynkuet came to market based on evidence of their ability to reduce the frequency and severity of hot flashes. AbCellera’s phase 2 study covered both endpoints, with the Canadian biotech reporting a mean reduction in severity of 1.4 points at Week 4 on ABCL635, compared to 0.3 points for placebo. Again, the placebo-adjusted result compares favorably to data on Veozah and Lynkuet. Analysts shared Hansen’s enthusiasm for the data. The phase 2 results “firmly validate ABCL635 as a potentially best-in-class treatment,” BMO Capital Markets analysts said in a note to investors Monday. ABCL635’s apparent efficacy edge “is likely attributable to the higher dosing/target engagement the asset is able to reach vs. the oral agents due to its wider therapeutic index,” the analysts added. The analysts, who model $2.3 billion in unadjusted peak sales for ABCL635, flagged the safety profile as another positive of the phase 2 readout. While Veozah carries a boxed warning for liver damage, nobody on ABCL635 in the phase 2 trial had elevated liver enzymes or bilirubin values. If replicated in phase 3, the lack of a liver signal could allow approval without the monitoring requirements imposed on Veozah. Investors appeared equally enthused, sending AbCellera's stock up 32% to $9.21 in premarket trading Monday from a Friday closing price of $6.93. Next, AbCellera will collect the Week 12 data and talk to its advisors about further development. The results open up “a wide variety of possibilities of how we might take this forward into phase 3 studies to truly maximize the value of the asset and make sure that ABCL635 is able to demonstrate its differentiation potential,” Sarah Noonberg, M.D., Ph.D., AbCellera’s chief medical officer, told investors.

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Aug 10 • 8:24 AM EDT • Health • fiercebiotech.com
Yorkshire Water to invest £35m to improve health of River Ouse

The water company's works will reduce the amount of phosphorus entering the River Ouse.

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Aug 10 • 6:28 AM EDT • Health • bbc.com
How to improve employee retention: Strategies to boost engagement and reduce turnover

Watch this Quick Take with Yeo & Yeo’s Amy Cell to learn employee retention strategies that build engagement, strengthen loyalty and reduce turnover.

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Aug 10 • 5:00 AM EDT • Business • crainsdetroit.com
Healthy midlife habits could delay dementia by up to 13 years, study finds

New research suggests that managing key health risks during middle age could significantly reduce the likelihood of developing dementia.

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Aug 9 • 5:53 PM EDT • Health • abc11.com
Nissan's in-factory AI cameras track employees to help worker safety

Nissan is using AI cameras to track how factory workers move. They say it reduces injuries and cut health and safety costs.

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Aug 9 • 5:48 AM EDT • Business • businessinsider.com
GLP-1s Like Ozempic, Mounjaro May Lower Fracture Risk in Type 2 Diabetes

A new study has found that GLP-1 medications, like Ozempic and Mounjaro, may help reduce the risk of fragility-related fractures in people with type 2 diabetes.

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Aug 9 • 2:38 AM EDT • Health • healthline.com
UVA School of Data Science launches assured enrollment program for 2026-2027 academic year

UVA School of Data Science has launched a new pilot program designed to reduce the application burden on students interested in the data science major.

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Aug 7 • 5:26 PM EDT • Science • 29news.com
Exclusive | Trump Administration to Award $2 Billion to Battery, Materials Companies

The deals add to a Pentagon funding spree to reduce U.S. dependence on China.

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Aug 7 • 3:17 PM EDT • Politics • wsj.com
Veteran Janet Meyer invests in Chattanooga firm through Veterans Entrepreneurship Program - Gary W. Rollins College of Business

Janet Meyers built community and confidence in her startup company through the Veterans Entrepreneurship Program at UTC.

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Aug 7 • 9:37 AM EDT • Business • blog.utc.edu
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Vitamin C may fight cancer — but not the way scientists once thought

Linus Pauling was widely mocked for claiming that vitamin C could fight cancer, especially after trials using vitamin C pills showed no benefit. Researchers now know that intravenous vitamin C reaches vastly higher concentrations and can behave more like an experimental cancer drug than an ordinary supplement. Early studies suggest it may damage vulnerable cancer cells, reduce treatment side effects, and possibly improve outcomes for some patients.

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Aug 7 • 8:00 AM EDT • Science • sciencedaily.com
The Business Training Fortune 500 Employees to Stay Safe at Work Makes Millions of Dollars for Its Unlikely Creator: ‘Sort of Magic’

COVE is on a mission to help people see — and reduce injuries on the job.

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Aug 6 • 3:00 PM EDT • Business • entrepreneur.com
Leprosy cases climb in Florida: Here’s how to reduce your risk

Leprosy is considered rare in the U.S., and most Americans catch the disease while traveling abroad.

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Aug 6 • 11:15 AM EDT • Health • thehill.com
IAM Union: Workers Deserve Protection from Deadly Heat

As record-breaking temperatures continue to put working people at risk across the country, the Trump Administration is pulling back protections for workers from one of the fastest-growing workplace hazards: extreme heat. Recent reports say the Occupational Safety and Health Administration (OSHA) has reduced the heat-focused inspections and enforcement efforts that were previously expanded under the

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Aug 6 • 9:24 AM EDT • Politics • goiam.org
The Five-Year Exit Plan Every Business Owner Should Start Today

A five-year exit plan helps business owners increase business value, reduce risk, and build a more sellable company long before they're ready to exit.

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Aug 6 • 5:00 AM EDT • Business • forbes.com
Dietitian weighs in on viral claim that bananas weaken smoothie health benefits

Registered dietitian nutritionist Ilana Muhlstein weighs in on claims that bananas reduce the health benefits of berries in smoothies, noting that the current research shouldn't be overstated.

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Aug 5 • 10:28 PM EDT • Health • foxnews.com
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World’s most-used weedkiller disrupts honeybee brains

Glyphosate was long thought to be safe for honeybees because they lack the enzyme the chemical targets in weeds. However, researchers found that exposed bees foraged 13 percent less after only three days and showed changes in brain chemicals linked to behavior. Across a whole hive, that decline could reduce honey production, weaken pollination, and threaten long-term survival.

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Aug 5 • 8:00 PM EDT • Science • sciencedaily.com
Advocates celebrate as California's first cardiac ablation is performed in ASC

Medicare is looking to reduce healthcare costs, and EPs believe outpatient procedures are more convenient for patients.

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Aug 5 • 5:07 PM EDT • Business • cardiovascularbusiness.com
The fight for safer cath labs continues: ‘We have to fix the work environment’

A group of nine U.S. medical societies wants to help hospital leaders improve cath lab safety. Their primary goals are to reduce radiation exposure and prevent orthopedic injuries.

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Aug 5 • 4:49 PM EDT • Business • cardiovascularbusiness.com
Study finds three midlife health factors that could delay dementia for 13 years

Research suggests addressing risk factors for poor cardiovascular health between the ages of 45 and 65 could help reduce risk of cognitive decline

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Aug 5 • 4:00 PM EDT • Health • theguardian.com
Swallowing faecal capsules reduces peanut allergy in six adults

Altering the gut microbiomes of people with peanut allergy using faeces donated from an allergy-free individual improved their peanut tolerance in a clinical trial

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Aug 5 • 2:00 PM EDT • Health • newscientist.com
Marvel Rivals’ next update drastically reduces the game’s install size on PC and console

As of Season 9.5, Marvel Rivals is going to take up a lot less space on your platform of choice.

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Aug 5 • 7:28 AM EDT • Technology • eurogamer.net
Fountain Square businesses plead for support as $14M project enters final phase

A $14 million drainage project in Indianapolis's Fountain Square neighborhood aims to reduce flooding, though local business owners report significant losses in foot traffic and sales during the ongoi...

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Aug 4 • 11:22 PM EDT • Business • yahoo.com
TCL Tab A1 Plus Nxtpaper is now available in the US

And its price is already reduced by 25%. TCL unveiled the Tab A1 Plus and its Nxtpaper variant in early March at MWC, and now the Nxtpaper version is...

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Aug 3 • 9:09 PM EDT • Technology • gsmarena.com