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Results for " rex " 663 found 🔀 AI-powered Shuffle

Why Elevance Earnings Gave Health Insurance Stocks A Cold; UNH Up Next

Elevance Health stock dived and inflected UNH and other S&P 500 health insurers after it easily beat Q2 forecasts, but only slightly hiked its outlook.

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Jul 15 • 8:56 AM EDT • Health • investors.com
UK's Reform Calls for 'Full Security' for Lawmakers After Politician's Murder

LONDON, July 15 (Reuters) - Britain's populist Reform UK called ⁠on ⁠Wednesday for all lawmakers ⁠to be given "full security" if they want it after the murder of Ann Widdecombe, a prominent member of the party led by veteran Brexit campaigner, Nigel ‌Farage. At a news conference, Zia ‌Yusuf,

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Jul 15 • 7:21 AM EDT • Politics • usnews.com
Mystery bidder buys T. rex nicknamed 'Gus' for a record $50 million

A Tyrannosaurus rex fossil billed as one of the world's largest and most complete specimens was sold for a record $50.1 million Tuesday to a mystery bidder.

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Jul 15 • 2:25 AM EDT • Technology • npr.org
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‘We Love Iraq,’ Trump Tells New Prime Minister in Oval Office Meeting

The meeting comes as President Trump’s administration has been ratcheting up pressure on Baghdad to diminish Iran’s influence in Iraq.

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Jul 14 • 2:53 PM EDT • Politics • nytimes.com
What science loses when ‘T. rex’ becomes a trophy

Sold for a record price of more than $50 million, ‘Gus’ was described by Sotheby’s as more than 60% complete.

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Jul 14 • 2:26 PM EDT • Science • theconversation.com
T. rex 'Gus' sells for record-breaking $50.1 million

The Tyrannosaurus rex skeleton surpassed its pre-sale estimate and set a new auction record for a dinosaur fossil.

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Jul 14 • 1:24 PM EDT • Technology • dw.com
T rex fossil ‘Gus’ sells for $50.1m at New York auction, setting new record

Skeleton judged to be one of the largest and most complete ever unearthed was excavated on a ranch in South Dakota

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Jul 14 • 11:31 AM EDT • Technology • theguardian.com
T. rex fossil sells for a monster price tag at NYC auction

One of the most complete fossils of the dinosaur that has captured humanity's imagination sold for millions during Sotheby's Natural History auction.

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Jul 14 • 11:30 AM EDT • Technology • usatoday.com
Xbox Project Helix Vs. PS6 - Data Firm Reveals Its Forecasted Sales Figures For Each

But also warns that the outcome "could look very different"

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Jul 14 • 9:30 AM EDT • Technology • purexbox.com
Former Xbox Dev Compulsion Games Shares Open Letter To 'Studios Across The Industry'

South of Midnight dev is back in business

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Jul 14 • 7:11 AM EDT • Technology • purexbox.com
Sotheby’s Big T. Rex Auction Raises Concerns Hype and Wealth Are Upending Science

Private buyers are increasingly outbidding museums for fossils. That’s making it difficult—or even impossible—for researchers to improve our understanding of the past.

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Jul 14 • 5:30 AM EDT • Science • wired.com
Sale of multimillion-dollar T rex skeleton is big headache for scientists

Palaeontologists warn before auction at Sotheby’s in New York that super-rich collectors are harming research

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Jul 14 • 12:00 AM EDT • Science • theguardian.com
This dinosaur fossil captures the final moments of a T. rex attack

A fossilized Edmontosaurus skull with a Tyrannosaurus tooth still embedded in its face has given scientists rare evidence of a dramatic predator-prey encounter. The discovery suggests the giant carnivore delivered an incredibly powerful face-to-face bite, offering new clues about how Tyrannosaurus hunted.

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Jul 13 • 8:00 PM EDT • Science • sciencedaily.com
Trump’s Cease-Fire Effectively Collapses as He Vows to Restart Blockade and Tolls

After several days of strikes, the president notified Congress that fighting had begun again and announced shipping fees that his administration previously deemed illegal.

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Jul 13 • 6:20 PM EDT • Politics • nytimes.com
T. Rex 'Gus' Could Make History, Then Disappear

Experts fear monumental fossil heading to auction will be lost to science

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Jul 13 • 5:15 PM EDT • Technology • newser.com
The Elder Scrolls Online Is Planning A 'Revised Roadmap' Following Xbox Layoffs

"The plan is still to deliver great content"

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Jul 13 • 9:30 AM EDT • Technology • purexbox.com
A chance encounter led to one of the largest T. rexes ever found. Now, it could be ‘lost to science’

A large T. rex skeleton nicknamed ‘Gus’ is on track to break auction records, and highlight one of paleontology’s biggest predicaments.

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Jul 13 • 7:04 AM EDT • Technology • cnn.com
A chance encounter led to one of the largest T. rexes ever found. Now, it could be ‘lost to science’

A large T. rex skeleton nicknamed ‘Gus’ is on track to break auction records, and highlight one of paleontology’s biggest predicaments.

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Jul 13 • 7:04 AM EDT • Science • cnn.com
Xbox Seems To Be Making A Fortune On The New Black Ops Ports For PS5

They've been spotted trending higher than GTA 6

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Jul 13 • 7:00 AM EDT • Technology • purexbox.com
Want to own a real T. rex? It could cost you $30 million

The Tyrannosaurus rex fossil known as "Gus" will go up for auction on Tuesday. It's not the first time dinosaur bones have been sold to the highest bidder.

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Jul 12 • 8:14 PM EDT • Technology • npr.org
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The Rare Pyrex Bowl Produced For Only A Year That Collectors Dream Of Finding At Thrift Stores

Pyrex’s Black Tulip casserole dish is a rare find for thrifters because its pattern of black flowers and pinwheels was only produced from 1956 to 1957.

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Jul 12 • 12:00 PM EDT • Technology • housedigest.com
T. rex fossil could become most expensive dinosaur ever sold

A 67 million-year-old Tyrannosaurus rex will go on sale in New York with a pre-sale value of $30m.

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Jul 11 • 7:58 PM EDT • Science • bbc.com
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T. rex fossil could become most expensive dinosaur ever sold

A 67 million-year-old Tyrannosaurus rex will go on sale in New York with a pre-sale value of $30m.

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Jul 11 • 7:58 PM EDT • Science • bbc.co.uk
T. rex fossil could become most expensive dinosaur ever sold

A 67 million-year-old Tyrannosaurus rex will go on sale in New York with a pre-sale value of $30m.

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Jul 11 • 7:58 PM EDT • Technology • bbc.com
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Skip Pyrex: The Antique Dishware You Can Find At Thrift Stores That's A 'True Collector's Jewel'

The Le Creuset Dutch Oven Terrine is unique. Shaped like a duck and no longer in production, this piece is a rare and interesting twist on plain cookware.

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Jul 11 • 7:40 PM EDT • Technology • housedigest.com
Xbox Sends Out Brief Statement Regarding 'Inaccurate' id Tech Reports

They say dozens of people are still working on the engine

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Jul 10 • 12:00 PM EDT • Technology • purexbox.com
Digital Foundry Shares Its Initial Analysis Of Black Ops 1 For PS5 Vs. Xbox

"This is a deeply odd state of affairs"

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Jul 10 • 10:30 AM EDT • Technology • purexbox.com
Former Tory minister Ann Widdecombe dies at 78

Ann Widdecombe became a dominant pro-Brexit voice later in her career.

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Jul 10 • 1:29 AM EDT • Politics • bbc.com
Bombing Iran, Then a Tentative Accord Didn’t Work. Does Trump Have a Plan C?

The administration appears to be reverting to an all-stick, no-carrot approach. But it has yet to answer why it believes economic warfare and bombing will yield a different result this time.

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Jul 9 • 8:52 PM EDT • Politics • nytimes.com
Black Ops 1 & 2 Now Live On PS5, Here's Some Early Footage Compared To Xbox

A surprise shadow drop

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Jul 9 • 2:10 PM EDT • Technology • purexbox.com
AC Black Flag Resynced Comparison Shows Difference Between Xbox Series X And Series S

How the Xbox versions stack up

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Jul 7 • 6:33 AM EDT • Technology • purexbox.com
These 20+ Games Are Coming To Xbox Next Week (July 6-10)

Including at least two more Game Pass additions

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Jul 4 • 8:05 AM EDT • Technology • purexbox.com
Long Reads for the Long Weekend

(Welcome to the Entertainment Strategy Guy, a newsletter on the entertainment industry and business strategy. I write a weekly Streaming Ratings Report and a bi-weekly strategy column, along with occasional deep dives into other topics, like today’s article. Please subscribe.) Happy Fourth of July weekend! As has been a tradition of mine going back to the beginning of the EntStrategyGuy website, I’m sharing my favorite long reads of the last year, like I did in 2019, 2020, 2021, 2024, and 2025. Let’s dive right in! Subscribe “Different Prices for the Same Ride: How Uber and Lyft Use AI to Get More Money Out of You“ by Derek Kravitz in Consumer Reports I don’t think surveillance pricing, like the kind described in this brilliant Consumer Reports article, is long for the world—it’s toxically unpopular—but we’ll see if either party takes on this issue. If I ran a political party focused on affordability, I would focus on a few pro-consumer and pro-market policies: Banning non-compete agreements. Ending surveillance pricing Eliminating junk fees (read more here...) Ensuring “right to repair” for consumer (and military!) products Capping excessive app store fees Stopping digital/algorithmic price-fixing tools. Preventing automatic subscription price increases. And more. If you want to fight inflation, there are a lot of great ways to do it quickly. Speaking of higher prices... “Secret Documents Show Pepsi and Walmart Colluded to Raise Food Prices Across the Economy“ by Matt Stoller in BIG Again, I think a political party should focus on lowering prices for consumers. And deals like this—Walmart making a deal/forcing Pepsi to offer the lowest prices at its stores and nowhere else—hypothetically lower prices at Walmart...but raise them everywhere else. “15 DUIs, still driving: California’s failure to take repeat drunk drivers off the road“ by Robert Lewis and Lauren Hepler in CalMatters CalMatters does terrific reporting in California, something the Golden State desperately needs more of, and this article is a great example of that. “PugLips: The next insanely popular thing you’ve never heard of…” by Simon Carless in Game Discover Co I thought that this parody article (and yes, it’s a parody, but I was definitely unsure at first) was hilarious and totally nailed how much tech/business journalism feels these days. Actually, three of my favorite articles this year were on hype in the video game industry, including Georg Zoller’s “The Video Game Industries Very Dark Night”—which I linked to recently and wrote a follow-up here—and Owen Mahoney’s “Derek Zoolander, Videogame Exec”. In particular, I like Mahoney’s focus on user experience as a guide to what trends will actually grab hold of customers. “The Matrix Lies“ by Evan Shapiro in Media War & Peace Evan Shapiro’s first person account of his experience with AI was hilarious. I think LLMs capabilities have significantly grown from last summer, and yet...my editor/researcher just had an abysmal experience using an LLM to do a quite basic task (which our LLM normally does each week) and the LLM made a mistake on every single data entry...along with seven different mistakes affecting twelve of the twenty or so entries, including mistakes that are explicitly spelled out in the prompt. That’s a brutal failure rate. Again, if you use AI/LLM for data collection, you need to take a lot of extra steps to verify and check the data. “Ghosts in the Balcony: A Cross-Country Trip to 58 Theaters Fighting to Survive“ by Matthew Frank in The Ankler I thought Matthew Frank’s pitch to head across America to visit theaters sounded insane aggressive at the time—at least it felt that way to someone a decade older than him; man, to be in your twenties again, am I right?—but I knew the result would be great. And it was, a terrific feature by a great young writer. Also, I loved Matthew’s recent article on who’s getting the precious few entry level jobs in Hollywood. (Hint: nepotism.) “Disney erased FiveThirtyEight“ and “Did Las Vegas get too greedy?” by Nate Silver in Silver Bulletin I love media history and analysis, and there’s no one better to get the history of FiveThirtyEight than from Nate Silver, who wrote about his personal experience in one of my favorite pieces from this year. I also loved Nate’s breakdown of what’s causing Vegas’ woes, but I’ll offer one criticism, summarized as “Might I suggest antitrust?” Many centrists/center-right/libertarian thinkers (Nate is self-described as the latter) often don’t consider consolidation or antitrust as factors in policy issues like housing, America’s military readiness, or, in this case, Las Vegas. Even if libertarians want to debunk antitrust/consolidation concerns, I’d love to read that debunking. In this case, Vegas is incredibly consolidated (though it also has been for a long time) and I’d have loved to read Nate at least contending with this factor, since he addresses almost every other potential factor for Vegas’ decline. “Why Microsoft’s Carbon Removal Pullback Is Such a Big Deal“ by Robinson Meyer in Heatmap News I’m a big supporter of carbon removal efforts, but this nascent industry faces a lot of headwinds, including this big move most recently. I think it’s clear that solar panels and batteries should be able to get the world to its carbon footprint goals, but effective carbon renewal remains necessary to prevent the worst impacts of global warming. “AI is killing the cheap smartphone“ by David Oks LLMs and AI will impact the world in ways we’re not ready for, and already, third world countries are seeing the prices of cheap cellphones skyrocket due to the cost of chips skyrocketing. This article by David Oks is a terrific breakdown. “100 Days of Madness: Netflix, Paramount, Warner and the Future of Hollywood“ by Wade Major at Hollywood Heretic Wade Major dove deep into Hollywood/streaming’s financials in this must read piece. Not that I agree with everything in this article (read my take on Warner Bros./Paramount here) but the analysis is top notch. I think many people discount how quality thinking, regardless of the argument/conclusion, will make you a better thinker. “Erased by the UFC: Frank Shamrock, The MMA GOAT of the 20th Century“ by Nate Wilcox in The MMA Draw Newsletter Growing up playing the UFC fighting game on the Dreamcast, Frank Shamrock was my favorite MMA fighter, and this history/tribute to him was great. Other Fun Reads “The Hardest Part Of History To Tell Is How It Felt“ by Craig Fehrman at Defector “Unmasking the Sea Star Killer“ by Craig Welch at bioGraphic “What Could Save the Industry? Fin-Syn“ by Richard Rushfield in The Ankler Alex Rollins Berg in Underexposed on movie bumpers, pillow shots, Disney trash cinema, cult films, and Casablanca. David H. Montgomery in YouGov’s The Surveyor on punctuation marks, condiments, dinosaurs, and comic strips and kids media. “How Medium finally pivoted its way to profitability“ and “Why the best journalists on YouTube are all former Vox employees“ by Simon Owens in Simon Owens’s Media Newsletter “It’s Not Just You, Netflix Shows Have Gotten Slightly Shorter: Here’s What the Data Says“ by Kasey Moore at What’s on Netflix “Numlock Awards: How Diane Warren became the biggest loser in Oscar history“ by Nathaniel Rakich and “Numlock Awards: The Oscar Bait era is over. The Oscar Chum era is here.” by Walt Hickey & Michael Domanico at Numlock Awards

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Jul 3 • 2:38 PM EDT • Entertainment • entertainment.substack.com
Smith Named CAA Leadership and Sports Excellence Award Winner for Swimming & Diving

RICHMOND, Va. - Drexel's Sebastian Smith has been named one of the 19 recipients of the prestigious CAA Leadership and Sport Excellence Award for the 2025-26...

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Jul 2 • 6:10 AM EDT • Sports • drexeldragons.com
11 Games Are Leaving Xbox Game Pass In Early July 2026

Here's what's leaving soon

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Jul 2 • 6:00 AM EDT • Technology • purexbox.com
Black Flag Resynced's Full Resolution & FPS Details Revealed For Xbox Series X|S

All the visual & performance info you need

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Jun 29 • 12:37 PM EDT • Technology • purexbox.com
Xbox Expects The 'Component Crisis' To Get Worse For Consoles In 2027

Specifically for console storage and memory prices

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Jun 29 • 10:15 AM EDT • Technology • purexbox.com
Xbox Announces 'Record' Pre-Orders For GTA 6 In Response To New Report

A rare statement has been issued

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Jun 29 • 6:00 AM EDT • Technology • purexbox.com
The 10 'Most Wishlisted' Upcoming Xbox Games According To Microsoft

Based on the MS Store's new filter

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Jun 28 • 10:00 AM EDT • Technology • purexbox.com
Here's How The New Xbox Prices Compare To PS5, Switch 2 & Steam Machine

Going live as of August 2026

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Jun 26 • 6:00 AM EDT • Technology • purexbox.com
Elroy Air to Become Publicly Traded Company via Business Combination with Inflection Point-led SPAC

Elroy Air, Inc., a leading U.S.-based technology developer of autonomous heavy-cargo drones for defense, rapid response and commercial logistics, and Columbu...

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Jun 26 • 6:00 AM EDT • Business • businesswire.com
UK food and drink exports fall as US tariffs and Brexit trade friction bites

Rolling coverage of the latest economic and financial news

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Jun 26 • 2:04 AM EDT • Business • theguardian.com
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Making Our Own Luck

We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.

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Jun 25 • 4:48 PM EDT • Science • goodscience.substack.com
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Prime Day 2026 LIVE: our home cinema experts' picks of the best OLED TV, Dolby Atmos soundbar, projector deals and more

We’re recommending the top savings, on and off Amazon, in real time

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Jun 25 • 3:09 AM EDT • Technology • whathifi.com
How Brexit broke British politics

Brexit has had a lasting impact on British politics, causing a decade of turmoil and division, and resulting in the resignation of Prime Minister Keir Starmer after two years of economic stagnation and a divided electorate.

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Jun 24 • 4:12 PM EDT • Politics • sentinelcolorado.com
How Brexit broke British politics

Brexit fractured the European Union, and it broke British politics. The country is about to get its seventh prime minister since the 2016 vote to leave the EU. Labour Prime

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Jun 23 • 3:24 AM EDT • Politics • kdhnews.com
How Brexit broke British politics

Brexit fractured the European Union, and it broke British politics. The country is about to get its seventh prime minister since the 2016 vote to leave the EU. Labour Prime

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Jun 23 • 3:24 AM EDT • Politics • djournal.com
How a dead extremist Rabbi still shapes Israeli politics today
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Jun 23 • 3:17 AM EDT • Politics • aljazeera.com
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Britain left the EU 10 years ago. Its politics has been an unruly mess

Brexit fractured the European Union, and broke British politics. A decade on, millions of voters have deserted the two big parties for alternatives.

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Jun 23 • 2:12 AM EDT • Politics • npr.org
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Brexit 10 years later: How the U.K. economy and politics changed, in charts

Ten years after the Brexit vote, CNBC compiled these charts show how the U.K. has changed across growth, immigration, sterling, trade and politics.

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Jun 23 • 1:00 AM EDT • Politics • cnbc.com
Britain left the EU 10 years ago. Its politics has been an unruly mess ever since

Brexit fractured the European Union, and it broke British politics

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Jun 23 • 12:04 AM EDT • Politics • abcnews.com
Ever since Brexit, British politics has been an unruly mess

Brexit fractured the European Union, and it broke British politics. The country is about to get its seventh prime minister since the 2016 vote to leave the EU.

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Jun 23 • 12:04 AM EDT • Politics • apnews.com
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Britain left the EU 10 years ago. Its politics has been an unruly mess ever since

Brexit fractured the European Union, and it broke British politics.

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Jun 23 • 12:04 AM EDT • Politics • clickondetroit.com
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Britain left the EU 10 years ago. Its politics has been an unruly mess ever since

LONDON (AP) — Brexit fractured the European Union, and broke British politics. The U.K. is about to get its seventh prime minister since June 23, 2016, a decade ago Tuesday, when the country voted …

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Jun 23 • 12:04 AM EDT • Politics • thehill.com
Brexit Has Cost the UK Growth, Analysts Say, in the Decade Since the Vote

Citing lower trade and investment, analysts broadly agree that Britain’s economy is smaller than it would have been if the country had stayed in the E.U.

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Jun 23 • 12:00 AM EDT • Business • nytimes.com
ANALYSIS: Fear not Britain, the EU doesn't agree on you rejoining either

Brussels heavyweights are clashing over whether Brexit can be reversed and on what terms

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Jun 22 • 10:00 PM EDT • Politics • euractiv.com
Draft Profile: Nikita Klepov

The OHL's points leader should hear his name called in round one later this week.

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Jun 22 • 7:17 PM EDT • Sports • sports.yahoo.com
Prime Day 2026 LIVE: all the top TV, soundbar and projector deals handpicked by our home cinema experts

Our experts are updating this page in real-time with all the best (and worst) Prime Day AV deals

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Jun 22 • 10:58 AM EDT • Technology • whathifi.com
T. rex took 40 years to reach full size, scientists find

Tyrannosaurus rex may have been a much slower grower than scientists realized. A new study of 17 tyrannosaur fossils found that the giant predator likely took about 40 years to reach its full size of roughly eight tons, extending previous estimates by 15 years.

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Jun 21 • 8:00 PM EDT • Science • sciencedaily.com
Dinosaurs invaded downtown St. Paul for blockbuster 1986 Science Museum exhibit

The brontosaurus and a 10-foot-tall Tyrannosaurus rex had been floated down the Mississippi River from Minneapolis that morning on coal barges to drum up publicity for the exhibit. It worked.

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Jun 20 • 5:19 PM EDT • Science • twincities.com
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Halo: Campaign Evolved Has Some Weird Xbox Account Requirements For Local Co-Op

Not a big issue on Xbox Series X|S, but it potentially is on PS5

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Jun 20 • 9:30 AM EDT • Technology • purexbox.com
Halo Studios Unveils Six Hours Of Footage From Campaign Evolved's Main Menu

It's a beauty!

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Jun 19 • 11:30 AM EDT • Technology • purexbox.com
ROG Xbox Ally X20 Marks The 'Opportunity Of A Lifetime', But Expect A High Price

ROG’s Director of Product shares a little more of what to expect

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Jun 19 • 8:30 AM EDT • Technology • purexbox.com
Ubisoft+ Premium Is Free Across Xbox & PC For The Next Five Days

Just remember to cancel if you don't want it

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Jun 18 • 2:30 PM EDT • Technology • purexbox.com
Treyarch Confuses Xbox Fans With Black Ops 1 & 2 Reveal For PS5

"The games are compromised on both Xbox and PC"

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Jun 18 • 6:00 AM EDT • Technology • purexbox.com
Before Making a Deal, Trump Demanded Iran’s Surrender. He Got a Surprise.

While the Iranians suffered substantial losses in the war, they emerged from a confrontation with the world’s most powerful military having proved they can use economic chaos as a weapon.

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Jun 17 • 8:51 PM EDT • Politics • nytimes.com
'It's Going To Be Pretty Brutal' - Jason Schreier Reveals More On Upcoming Xbox Layoffs

The Bloomberg reporter has published a new 30-minute video

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Jun 17 • 12:10 PM EDT • Technology • purexbox.com
Starmer warns against ‘looking backwards’ to Brexit after rivals back UK’s return to EU

Speaking at the G7 summit, prime minister says he stands by Labour’s manifesto pledge not to rejoin bloc

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Jun 17 • 12:00 PM EDT • Politics • theguardian.com
Macy’s Fourth of July show to feature Post Malone, Blake Shelton, Salt-N-Pepa and Shaboozey

Macy's is set to celebrate America's 250th birthday with a spectacular July Fourth fireworks show featuring performances by Post Malone, Blake Shelton, Salt-N-Pepa, Noah Kahan, Bebe Rexha and Shaboozey.

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Jun 17 • 12:00 PM EDT • Entertainment • seattletimes.com
Vibrating pill could help predict relapse risk for anorexia nervosa patients

UCLA study shows a vibrating pill could help doctors determine if a patient with anorexia nervosa may have a higher risk of relapse.

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Jun 17 • 8:00 AM EDT • Health • uclahealth.org
Obama’s Nuclear Deal Looms Over Trump’s Iran Negotiations

President Trump is under pressure to significantly improve upon the Obama-era deal in order to justify the huge human and economic cost of taking the United States to war.

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Jun 16 • 7:15 PM EDT • Politics • nytimes.com
Compulsion Games Might Be Getting Shut Down By Xbox, Says Report

Update: Source says they're in negotiations with Microsoft

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Jun 15 • 1:04 PM EDT • Technology • purexbox.com
Rumour: Journalist Suggests Two Xbox Studios Are 'At Risk Of Being Closed' In 2026

One said to be a complete shock

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Jun 15 • 11:45 AM EDT • Technology • purexbox.com
Cubs' Struggles Should Lead to Ideal Phillies Trade

The Philadelphia Phillies moving on from one of their big prospects wouldn't come as much of a surprise at this trade deadline, though there are some others in the system who could be traded, even if they aren't as highly regarded as some of the other top players.

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Jun 14 • 11:16 PM EDT • Sports • sports.yahoo.com
Roundup: The Results From Our Xbox Games Showcase 2026 Predictions

They seemed like safe-ish bets, but we didn't do that well!

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Jun 14 • 11:00 AM EDT • Technology • purexbox.com
Six Games Are Confirmed For Xbox Game Pass In July 2026 So Far

An early look at what's to come

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Jun 13 • 9:30 AM EDT • Technology • purexbox.com
Why Brexit Still Haunts British Politics

A decade on from the referendum that led to Britain's exit from the European Union, the issue continues to divide and drive debate in Westminster.

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Jun 13 • 7:00 AM EDT • Politics • time.com
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Brexit ten years on: a decade of national ‘Bregret’?

Economists are still squabbling about how much Brexit has cost

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Jun 13 • 1:30 AM EDT • Politics • theweek.com
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Resurfacing to begin Monday on SH-33 Business Spur in Rexburg

Construction will eliminate street parking in the area work is occurring and happen mostly through the night as crews create a smoother ride through Rexburg.

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Jun 12 • 10:50 AM EDT • Business • itd.idaho.gov
Xbox's New Startup Animation Is Now Live For Everyone, Plus Four Other New Features

Or at least, it should be

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Jun 12 • 9:30 AM EDT • Technology • purexbox.com
Halo: Campaign Evolved Comparison Shows Difference Between Xbox Series X And Ally X

Based on early pre-release footage, of course

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Jun 11 • 2:30 PM EDT • Technology • purexbox.com
What did T. rex’s breath smell like?

Short answer: Really gross.

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Jun 11 • 9:01 AM EDT • Science • popsci.com
Community Days returns with expanded entertainment, parade and biggest fireworks show yet

DuBOIS — For 33 years, DuBois Community Days has brought residents together for a weekend of entertainment, food, family activities and hometown pride.

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Jun 11 • 5:00 AM EDT • Entertainment • thecourierexpress.com
US congressman helps secure $750,000 for rural hospital’s radiology expansion

Rep. Mike Simpson, R-Idaho, announced the news on June 10, with the money going toward Madison Memorial Hospital in Rexburg.

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Jun 11 • 2:37 AM EDT • Business • radiologybusiness.com
Here's What's In The 'Premium Upgrade' Editions For Fable, Gears & Halo On Xbox

Early access being one of the major perks

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Jun 10 • 8:30 AM EDT • Technology • purexbox.com
'We'll Start To See Radically Different Business Models' - Xbox Boss Talks Future Of Consoles

She says mass audiences can't afford thousands on a console generation

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Jun 9 • 7:00 PM EDT • Technology • purexbox.com
Arts, Beats & Eats adds veteran honors, a Pride stage, T-rex and more

The festival has also made a deal with Royal Oak to stay in the city at least through 2030.

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Jun 9 • 11:00 AM EDT • Entertainment • detroitnews.com
GREX-PLUS Science Book v2

GREX-PLUS (Galaxy Reionization EXplorer and PLanetary Universe Spectrometer) is a mission candidate for a JAXA strategic L-class mission to be launched in the 2030s

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Jun 9 • 9:51 AM EDT • Science • astrobiology.com
Xbox Employee Responds To New Trailer Showing PS5 Logo For Gears Of War E-Day

"I can confirm this is not true"

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Jun 8 • 7:00 PM EDT • Technology • purexbox.com
Trump Wants to Call the Shots. But in Iran, He Keeps Hitting His Limits.

President Trump is grappling with his own version of the sort of Middle East crisis that beset his predecessors, and that he promised to avoid.

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Jun 8 • 5:49 PM EDT • Politics • nytimes.com
GENESIS, U.S. SOCCER FOUNDATION, AND MLS PLAYERS ASSOCIATION SUPPORT YOUTH SPORTS WITH NEW MINI-PITCH IN ILLINOIS

/PRNewswire/ -- Genesis, U.S. Soccer Foundation, and the Major League Soccer Players Association (MLSPA) opened a new mini-pitch at Drexel Elementary School in...

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Jun 8 • 11:12 AM EDT • Sports • prnewswire.com
Understanding anorexia’s grip on the brain could unlock new therapies

One-third of people with anorexia nervosa don’t recover and treatment has remained stagnant for years. Now we’re beginning to understand how the condition takes over the mind

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Jun 8 • 9:00 AM EDT • Health • newscientist.com
Businesses fear for economy if Swiss vote to cap population at 10 million

Switzerland goes to the polls on June 14 to vote on whether to cap its population at 10 million people in a referendum some have likened to a "Swiss Brexit", alarming many businesses who fear an economic blow should the proposal succeed.

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Jun 8 • 2:01 AM EDT • Business • reuters.com
U.S. Investors Target Wrexham-Style Turnaround with Italian Soccer Club

The deal is expected to close this month.

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Jun 7 • 5:41 PM EDT • Sports • sports.yahoo.com
Matt Booty Explains Xbox's Plans For Exclusive Games Going Forward

"We know exclusives are important"

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Jun 7 • 4:55 PM EDT • Technology • purexbox.com
Senua Brings A 'Different Kind' Of Hellblade Game To Xbox Game Pass In 2027

We're here for it

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Jun 7 • 3:34 PM EDT • Technology • purexbox.com
Xbox Fans Go Wild As Asha Sharma Gives Free Consoles To Everyone At FanFest LA

Watch the reaction here

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Jun 7 • 3:15 PM EDT • Technology • purexbox.com
21 Game Pass Titles Get New Announcements At The Xbox Showcase 2026

Talk about a stacked lineup!

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Jun 7 • 2:57 PM EDT • Technology • purexbox.com
Halo: Campaign Evolved Gets July 2026 Release Date For Xbox, PC & PS5

Master Chief returns next month

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Jun 7 • 1:19 PM EDT • Technology • purexbox.com
Roundup: All The Xbox Reveals From The Future Games Show 'Summer Showcase' 2026

There were plenty of them!

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Jun 6 • 5:30 PM EDT • Technology • purexbox.com