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Double plays help Jesuit-Brother Martin winner create tie atop Catholic League standings

The teams will play a second game Thursday at Kirsch-Rooney Stadium.

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Mar 25 • 5:01 AM EDT • Sports • nola.com
Mills halts kennel ordinance at second reading amid showing for business owner

MILLS, Wyo. — Mills City Council has shelved a proposed ordinance affecting kennels and catteries on second reading. Mills City Attorney Pat Holscher told

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Mar 25 • 12:43 AM EDT • Business • oilcity.news
Austin establishes microloan hub for small businesses

The city of Austin announced on Tuesday it’s teaming up with global nonprofit Kiva to launch the second Kiva hub in Texas, allowing small business owners to apply for microloans and coaching.

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Mar 24 • 6:21 PM EDT • Business • kxan.com
Tua Tagovailoa gets a second chance in Atlanta: 'Got to play better football'
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Mar 24 • 1:52 PM EDT • Sports • sports.yahoo.com
Losses triple for Highmark Health in 2025: ‘We’re still in the middle of the storm’

Despite revenue gains, operating losses continued for the second consecutive year in 2025 at hospital and health insurance giant Highmark Health as the...

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Mar 24 • 12:07 PM EDT • Health • post-gazette.com
AI compressed billions of years of evolution into seconds to create 'Lego-like robots' that can recover even when they lose limbs

Modular robots are easily expandable, know when they're upside down or stuck, and can march forward across all kinds of terrain.

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Mar 24 • 11:30 AM EDT • Science • livescience.com
Houston, Illinois carry strong opening-weekend efficiency in March Madness

The second-seeded Cougars — who played in last year's national-title game — rolled to 31-point wins against both Idaho and Texas A&M.

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Mar 24 • 9:33 AM EDT • Sports • spectrumlocalnews.com
The US in Brief: DHS’s new boss

The latest news in US politics, with coverage of Donald Trump’s second term.

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Mar 24 • 6:42 AM EDT • Politics • economist.com
Colorado’s Tamale Act may decide whether home cooks can build a business

An eclectic coalition, including the MAHA call for “food freedom,” gave the law a second chance as backers push for immigrant assistance and entrepreneurship.

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Mar 24 • 5:00 AM EDT • Business • washingtonpost.com
Freeway series game II chat

The Dodgers play their first game at Dodger Stadium since Game 5 of last year’s World Series on Monday, hosting the Angels for the second of a three-game exhibition series. Roki Sasaki goes for the Dodgers against left-hander Reid Detmers. MONDAY GAME INFO

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Mar 23 • 8:54 PM EDT • Sports • sports.yahoo.com
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Milledgeville teen runs car detailing business in school, wins $1,000 in chamber contest

At 19 years old, Kyan Silas has started a successful business and received second place in the youth entrepreneur program, landing him a $1,000 prize.Kyan Sila

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Mar 23 • 8:47 PM EDT • Business • wgxa.tv
Secondary Trauma and Healthcare Providers | Modern Midwives Blog |…

Secondary trauma is a common form of distress experienced by anyone who is witness to the trauma another person experiences. Those who work in the…

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Mar 23 • 8:00 PM EDT • Health • pbs.org
2026 NCAA Tournament second round schedule: March Madness bracket, game dates, tip times, TV channels

Check out the master schedule for the first and second rounds of the 2026 NCAA Tournament so you can watch all the March Madness

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Mar 23 • 2:50 PM EDT • Sports • cbssports.com
Borussia Dortmund names second-division exec as sporting director

Borussia Dortmund has dipped into the German second division to appoint a new sporting director who won praise for making impactful transfers on a budget.

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Mar 23 • 12:43 PM EDT • Sports • espn.com
Rahm Emanuel proposes banning all federal employees from betting on prediction markets
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Mar 23 • 9:47 AM EDT • Politics • cbsnews.com
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Illinois, the youngest team in Women's NCAA tournament, proving age is just a number

No. 7 seed Illinois faces No. 2 seed Vanderbilt in Nashville in the second round of the Women's NCAA Tournament.

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Mar 23 • 7:03 AM EDT • Sports • usatoday.com
Ohio State vs Notre Dame predictions, picks, odds for NCAA Tournament Second Round

Our March Madness experts pick the winner for No. 3 Ohio State vs No. 6 Notre Dame in the 2026 women's NCAA Tournament on March 23

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Mar 23 • 5:08 AM EDT • Sports • usatoday.com
UConn vs Syracuse predictions, picks, odds for NCAA Tournament Second Round

Our March Madness experts pick the winner for No. 1 UConn vs No. 9 Syracuse in the 2026 women's NCAA Tournament on March 23

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Mar 23 • 5:08 AM EDT • Sports • usatoday.com
Where to watch South Carolina vs. USC in March Madness Second Round: Time, TV Channel

The No. 1 South Carolina Gamecocks face the 9 USC Trojans in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 23 • 5:08 AM EDT • Sports • usatoday.com
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Experience shone through for Manchester City at Wembley against Arsenal

Manchester City claimed the first piece of silverware for the 2025/26 season with their 2-0 win over Arsenal at Wembley in yesterday’s Carabao Cup final. A second half brace from Nico O’Reilly was...

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Mar 23 • 2:35 AM EDT • Sports • sports.yahoo.com
TCU completes comeback, avoids Washington's NCAA Tournament upset bid

TCU women's basketball’s 62-59 overtime win over Washington in the second round of March Madness wasn’t pretty, but it was resilient.

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Mar 23 • 2:04 AM EDT • Sports • usatoday.com
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Kansas squanders its best player as Darryn Peterson's college career with second-round loss to St. John's

The Peterson era in Lawrence is likely over.

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Mar 22 • 9:54 PM EDT • Sports • cbssports.com
Kansas coach Bill Self unsure about future after buzzer-beater loss to St. John's: 'I haven't decided'

After a heartbreaking last-second loss in the second round of the NCAA tournament, Self wasn't ready to discuss his coaching future.

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Mar 22 • 8:39 PM EDT • Sports • sports.yahoo.com
Alabama vs. Texas Tech odds, time, March Madness predictions: 2026 NCAA Tournament picks from proven model

SportsLine's model has revealed its Texas Tech vs. Alabama picks for the NCAA Tournament 2026 second-round game on Sunday

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Mar 22 • 8:03 PM EDT • Sports • cbssports.com
Wisconsin edges Ohio St., wins another title at Frozen Four

Claire Enright scored the go-ahead goal in the third period Sunday, Ava McNaughton had 34 saves, and No. 2 seed Wisconsin beat top-seeded Ohio State 3-2 at the Frozen Four to win its second consecutive national championship.

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Mar 22 • 7:21 PM EDT • Sports • espn.com
‘Project Hail Mary’ blasts off with $80.5 million, a best for Amazon MGM, and the year

Studio estimates on Sunday say Amazon MGM's “Project Hail Mary” has topped the North American box office charts with $80.5 million in ticket sales — the second biggest ever for a non-franchise film.

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Mar 22 • 4:55 PM EDT • Entertainment • scrippsnews.com
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Phillies pitcher Daniel Robert stable after second medical emergency in six months

Daniel Robert suffered a cardiac event Sunday — the second in six months — but was stable after his defibrillator activated

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Mar 22 • 3:39 PM EDT • Sports • nbcsportsphiladelphia.com
Your Thymus and Your Healthspan

Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.

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Mar 22 • 2:18 PM EDT • Health • erictopol.substack.com
Kentucky vs. Iowa State odds, time, March Madness predictions: 2026 NCAA Tournament picks from proven model

SportsLine's model has revealed its Kentucky vs. Iowa State picks for the NCAA Tournament 2026 second-round game on Sunday

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Mar 22 • 1:03 PM EDT • Sports • cbssports.com
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Scientists Uncover Hidden “Second Layer” in Human DNA

A newly identified cellular system monitors subtle variations in genetic coding, hinting at a hidden level of control over how genes are expressed.

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Mar 22 • 11:02 AM EDT • Science • scitechdaily.com
Boys' basketball coach of the year: Mike LeDuc of Damien

The second-winningest coach in California high school history guided Damien to the state Division I championship.

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Mar 22 • 7:10 AM EDT • Sports • latimes.com
Duke vs Baylor predictions, picks, odds for NCAA Tournament Second Round

Our March Madness experts pick the winner for No. 3 Duke vs No. 6 Baylor in the 2026 women's NCAA Tournament on March 22

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Mar 22 • 5:08 AM EDT • Sports • usatoday.com
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Where to watch Minnesota vs. Ole Miss in March Madness Second Round: Time, TV Channel

The No. 4 Minnesota Golden Gophers face the 5 Ole Miss Rebels in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 22 • 5:06 AM EDT • Sports • usatoday.com
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Where to watch Duke vs. Baylor in March Madness Second Round: Time, TV Channel

The No. 3 Duke Blue Devils face the 6 Baylor Bears in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 22 • 5:06 AM EDT • Sports • usatoday.com
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Where to watch Oklahoma vs. Michigan State in March Madness Second Round: Time, TV Channel

The No. 4 Oklahoma Sooners face the 5 Michigan State Spartans in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 22 • 5:06 AM EDT • Sports • usatoday.com
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What time is Michigan women's basketball's second round game?

Michigan cruised to a blowout victory over Holy Cross in their opening NCAA Women's Tournament matchup. See who they play next.

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Mar 22 • 4:46 AM EDT • Sports • sports.yahoo.com
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Politics: Iowa Senate majority leader outlines plans for coming weeks

Second funnel week concluded in the Iowa Legislature, meaning that lawmakers’ focus can return to funding, appropriations and other types of specific bills that don’t respond to the Legislature’s self-imposed

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Mar 22 • 2:00 AM EDT • Politics • telegraphherald.com
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2025-26 Women's Second Round Odds: Spreads, Lines for all 16 Games

Check out the odds for all 16 games of the women's NCAA Tournament Round of 32.

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Mar 22 • 1:52 AM EDT • Sports • foxsports.com
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Paxton Aaronson scores twice to propel Rapids to 4-1 victory over Sporting KC

Paxton Aaronson scored a goal in each half, Wayne Frederick's first career goal was the go-ahead score and the Colorado Rapids rolled to a 4-1 victory over Sporting Kansas City on Saturday night. Aaronson gave Colorado (3-2-0) the lead in the 12th minute, but Shapi Suleymanov scored for the first time this season — in the 44th — to pull Sporting KC (1-3-1) even. The tie lasted until the second minute of stoppage time when Frederick scored unassisted for a 2-1 lead at halftime.

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Mar 22 • 1:40 AM EDT • Sports • sports.yahoo.com
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France Is Voting for Thousands of New Mayors. Here’s Why It Matters.

The far-right party had first-round successes in several cities, but so did the far left. Sunday’s second round may clarify who has real momentum.

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Mar 22 • 12:01 AM EDT • Politics • nytimes.com
OU women's gymnastics senior Faith Torrez scores perfect 10, while Sooners lose in SEC championship

No. 1 OU women’s gymnastics (18-1-1) finished second in the Southeastern Conference Championship against No. 3 Florida (15-2-0), No. 2 LSU (12-5-1) and No. 4 Alabama (9-8-0) Saturday, with the

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Mar 21 • 11:42 PM EDT • Sports • oudaily.com
Black Family Wellness Expo returns to Wichita, promotes health awareness for second year

Organizers say more than 40 different vendors participated in the expo.

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Mar 21 • 10:46 PM EDT • Health • kwch.com
Chuck Norris's Second Highest-Rated Movie Is One He Spent About 30 Seconds In

The second highest-rated movie associated with Chuck Norris is one he didn't even have a starring role in.

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Mar 21 • 10:16 PM EDT • Entertainment • mensjournal.com
Coaches in elite company clash when Kansas faces St. John's

SAN DIEGO -- Only three active head coaches in Division I college basketball have won multiple national championships. Two of them meet for a berth in the Sweet 16 when Bill Self's No. 4 Kansas Jayhawks face Rick Pitino's No. 5 St. John's Red Storm on Sunday in the second round of the NCAA Tournament East Region.

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Mar 21 • 9:01 PM EDT • Sports • cbssports.com
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March Madness scores: Live updates, schedule for today's NCAA Round 2

Keep up with today's Men's NCAA Tournament second round with scores, highlights, game times and how to watch March Madness Round 2.

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Mar 21 • 4:15 PM EDT • Sports • usatoday.com
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Mainieri out as South Carolina's baseball coach in 2nd season

Paul Mainieri is out as South Carolina's baseball coach midway through his second season after he couldn't approach the level of success he had produced at LSU.

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Mar 21 • 3:22 PM EDT • Sports • espn.com
Ranking 5 most likely March Madness upsets in NCAA Tournament second round

The second round of 2026 NCAA Tournament is underway. Here's a look at the five most likely March Madness upset predictions in the Round of 32.

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Mar 21 • 11:20 AM EDT • Sports • usatoday.com
Physicists created an electron 'catapult' that moves particles at 'extraordinary' speed

Using a new method, physicists found a way to 'catapult' electrons across solar materials in quadrillionths of a second.

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Mar 21 • 11:00 AM EDT • Science • livescience.com
Duke vs. TCU odds, March Madness predictions: 2026 NCAA Tournament picks from proven model

SportsLine's model has revealed its Duke vs. TCU picks for the NCAA Tournament 2026 second-round game on Saturday

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Mar 21 • 8:32 AM EDT • Sports • cbssports.com
Jack Draper blown away in ‘difficult’ Miami Open exit

The giant Opelka fired down 25 aces and 47 winners in two tiebreak sets, winning 7-6 (3) 7-6 (0), as Draper suffered a second-round exit

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Mar 21 • 3:06 AM EDT • Sports • sports.yahoo.com
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Kakaako jewelry business robbery suspect is charged

Brian Bertoli, 34, the suspect in the robbery of a Kakaako jewelry business on Wednesday afternoon, was charged today with robbery in the second degree. His bail has been set at $100,000.

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Mar 21 • 2:00 AM EDT • Business • staradvertiser.com
Devils' win streak snapped with 2-1 loss to Capitals

Logan Thompson made 30 saves, losing his shutout bid with just 43 seconds remaining, and the Washington Capitals beat the New Jersey Devils 2-1 on Friday night.

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Mar 20 • 9:56 PM EDT • Sports • sports.yahoo.com
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2026 March Madness predictions: NCAA bracket expert picks odds for second round games on Saturday

Best bets for Saturday's second-round action in the 2026 NCAA Tournament

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Mar 20 • 9:17 PM EDT • Sports • cbssports.com
Michigan vs Saint Louis prediction, picks, odds for NCAA Tournament Second Round

Our March Madness experts pick the winner for No. 1 Michigan vs No. 9 Saint Louis in the 2026 NCAA Tournament on March 21

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Mar 20 • 8:21 PM EDT • Sports • usatoday.com
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Gonzaga vs Texas prediction, picks, odds for NCAA Tournament Second Round

Our March Madness experts pick the winner for No. 3 Gonzaga vs No. 11 Texas in the 2026 NCAA Tournament on March 21

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Mar 20 • 6:41 PM EDT • Sports • usatoday.com
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March Madness bracket predictions, picks for all Second Round games today

Our March Madness experts picked the winner for all games in the 2026 NCAA Tournament on March 21. See them all.

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Mar 20 • 6:17 PM EDT • Sports • usatoday.com
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63%
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Hubert Davis buyout: What it would cost UNC to move on from coach after first-round NCAA Tournament exit

The Tar Heels' second straight first-round NCAA Tournament exit adds to growing questions about the program's direction

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Mar 20 • 5:03 PM EDT • Sports • cbssports.com
Amazon is reportedly developing an AI-centric smartphone

Amazon's second smartphone could forego an app store.

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Mar 20 • 12:38 PM EDT • Technology • arstechnica.com
LSU's Flau’jae Johnson is back on March Madness stage. What to know about star guard

Star guard Flau'jae Johnson leads second-seeded LSU into a first-round NCAA Tournament game against the Jacksonville Dolphins. Here's what to know.

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Mar 20 • 8:03 AM EDT • Sports • usatoday.com
Valve releases SteamOS 3.8 preview with Steam Machine support and wider handheld compatibility

Valve SteamOS 3.8 preview is here Valve has released SteamOS 3.8.0 Preview, codenamed "Second Clutch," for the Steam Deck Preview channel. The update adds

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Mar 20 • 8:00 AM EDT • Technology • videocardz.com
The US in Brief: The rising cost of war

The latest news in US politics, with coverage of Donald Trump’s second term

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Mar 20 • 7:45 AM EDT • Politics • economist.com
March Madness second-round schedule: How to watch, follow Saturday's NCAA tournament action
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Mar 20 • 1:18 AM EDT • Sports • sports.yahoo.com
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Men’s NCAA Tournament Second Round Opening Odds: TCU vs. Duke

Horned Frogs battle top overall seed Blue Devils for a spot in the Sweet 16

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Mar 19 • 11:59 PM EDT • Sports • sports.yahoo.com
Victor Wembanyama drills game-winner to lift Spurs past Suns, clinch team's first playoff berth since 2019

Victor Wembanyama hit a game-winner over Oso Ighodaro in the final seconds on Thursday night at the Frost Bank Center.

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Mar 19 • 10:47 PM EDT • Sports • sports.yahoo.com
Markiplier to Microdramas: The Ankler x NAB Show’s Future of Entertainment

Share Subscribe Vegas, baby! The Ankler is heading back to NAB Show for a second year in a row — and doubling down on conversations with the smartest people in the industry. From April 18–22, we’re partnering again with the industry’s biggest media and tech gathering to break down the Business of Media and Entertainment as it’s actually evolving: faster, riskier and increasingly driven by new formats, new audiences and new power players. This curated series will bring together top creators, executives and innovators to tackle the forces reshaping the industry — from the AI disruption of Hollywood’s creative ecosystem to the rise of the creator economy, shifting audience behavior and the changing economics of production. We’ll be rolling out more programming in the coming weeks — including top speakers from leading AI studios, prediction markets and beyond — so keep an eye on the Business of Media and Entertainment hub. But first up, we’re announcing two panels about what’s actually working in Hollywood: The Scary-Smart Business of Horror A good scare has become one of the entertainment economy’s most reliable engines. With disciplined budgets, built-in fandoms and global box office upside, horror consistently outperforms. From theatrical releases to streaming-first originals and creator-driven IP, the genre is artistically flexible and financially durable — and one of the last truly communal experiences for Gen Z and Gen Alpha audiences. Join YouTube creator Mark Fischbach, aka Markiplier, whose independent feature Iron Lung earned more than $50 million at the global box office, Atomic Monster president Michael Clear and screenwriter Akela Cooper (M3GAN, Malignant) for a conversation moderated by Like & Subscribe’s Natalie Jarvey about why horror travels so effectively across platforms and borders, how studios and independents are building sustainable genre pipelines and why the next wave of breakout franchises may emerge from unexpected sources. Inside the Microdrama Boom Short-form serialized storytelling is having a major moment. Microdramas, social-native series and creator-led narratives are capturing massive audiences with low-cost, rapid production cycles and direct-to-fan distribution. What was once dismissed as niche or experimental is now attracting major platform investment. Moderated by Jarvey, this panel of microdrama creators and executives — including one of the format’s top stars and producers, Kasey Esser, and Dhar Mann Studios’ head of vertical content, Erin McFarlane — examines how format innovation, fandom dynamics and algorithmic discovery are reshaping the economics of scripted storytelling and what traditional studios can learn from these agile models. For sponsorship opportunities, contact Lynne@theankler.com Share

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Mar 19 • 6:34 PM EDT • Entertainment • theankler.com
😐 Neutral (16%)
wow
57%
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Louisville tops South Florida: Highlights and Postgame Videos

Feel free to watch every second of these, or turn the highlight videos off around the 9-minute mark of the second half. Either way, go ahead and soak this up. It’s been a while. Highlights: Pat Kelsey postgame from the bus: Locker room celebration:

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Mar 19 • 6:08 PM EDT • Sports • sports.yahoo.com
☹️ Negative (-5%)
No. 16 Siena nearly upsets No. 1 Duke in NCAA tournament while making only 1 sub ... for 2 seconds
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Mar 19 • 6:05 PM EDT • Sports • sports.yahoo.com
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😐 Neutral (0%)
wow
38%
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angry
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Virginia Tech adds commitment from EDGE Alexander Taylor

Baltimore (Md.) St. Frances Academy edge rusher Alexander Taylor committed to Virginia Tech on Thursday. The three-star prospect announced the decision on X. Taylor is the second commit in the Hokies’ 2027 recruiting class, joining three-star edge rusher Andrew Rogers.

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Mar 19 • 5:40 PM EDT • Sports • sports.yahoo.com
😐 Neutral (17%)
ahah
40%
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Mobile sports betting dies again in Mississippi Senate

It is the second time this session that a mobile sports betting bill from the House has died in the Senate.

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Mar 19 • 1:40 PM EDT • Sports • magnoliatribune.com
Illinois: Penn Entertainment's Hollywood Casino Aurora scheduled to open June 24

Penn Entertainment announced on Thursday that Hollywood Casino Aurora will open to the public on June 24, pending customary regulatory approvals. This will be the second new Penn property to... Read more »

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Mar 19 • 12:34 PM EDT • Entertainment • cdcgaming.com
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😐 Neutral (19%)
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70%
love
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PENN Entertainment Sets June 24 as Grand Opening Date for New Hollywood Casino Aurora in Illinois

WYOMISSING, Penn. & AURORA, Ill., March 19, 2026--PENN Entertainment, Inc. ("PENN" or the "Company") (Nasdaq: PENN) announced today that it expects to open the new land-based Hollywood Casino Aurora to the public on Wednesday, June 24, pending customary regulatory approvals. This will be the second all-new PENN property to open in the Chicagoland region following the grand opening of the land-based Hollywood Casino Joliet in August 2025.

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Mar 19 • 10:00 AM EDT • Entertainment • finance.yahoo.com
What a Recent Court Win Reveals About the Trump Administration’s Unlawful Attacks on Climate Science

This article was originally published by the Bulletin of the Atomic Scientists. The second Trump administration is taking its hostility to climate science to new levels. In addition to its rhetoric dismissing climate change as a con or scam, recently released government documents show how the adm

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Mar 19 • 9:00 AM EDT • Science • blog.ucs.org
Accenture Reports Second-Quarter Fiscal 2026 Results

Accenture reported financial results for the second quarter of fiscal 2026 ended February 28, 2026.

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Mar 19 • 6:39 AM EDT • Business • businesswire.com
How Barcelona exploited Magpies' defensive weakness

Champions League Match of the Day pundits Stephen Warnock and Nedum Onuoha look at how Barcelona were able to repeatedly expose Newcastle United's centre-backs Dan Burn and Malick Thiaw during their 7-2 victory in the second leg of their last-16 tie.

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Mar 19 • 3:39 AM EDT • Sports • sports.yahoo.com
😐 Neutral (25%)
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100%
Your NCAA Basketball Tournament Viewing Guide: March 19, 2026

Not just the 16 first round games on the men’s side, but the second pair of First Four games on the women’s side as well!

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Mar 19 • 3:00 AM EDT • Sports • sports.yahoo.com
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😐 Neutral (8%)
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Keaton Wagler earns All-American honors and jersey banner

Greenville, S.C. — The preseason hype surrounding a kid named Keaton Wagler felt rather obscure back then. Today, Keaton Wagler is considered one of the recent great Illini to grace the wooden State Farm Center court. On Tuesday, Illinois freshman Keaton Wagler was named to the All-American Second Team, the first Illini Freshman ever to […]

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Mar 19 • 1:06 AM EDT • Sports • sports.yahoo.com
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😐 Neutral (6%)
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Messi scores 900th career goal in Inter Miami cup clash

Argentine superstar Lionel Messi bagged the 900th goal of his glittering career on Wednesday, scoring for Inter Miami in their CONCACAF Champions Cup clash with Nashville.- Clinical finish - The Argentine World Cup winner's 900th goal came early in Miami's last-16 second leg tie with MLS rivals Nashville.

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Mar 18 • 8:07 PM EDT • Sports • sports.yahoo.com
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Cavs at Bulls: How to watch, odds, and injury report

The Cavaliers will look to pick up their second win on this three-game road trip.

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Mar 18 • 7:00 PM EDT • Sports • sports.yahoo.com
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March Madness bracket updates: First Four continues Wednesday; Texas tops NC State on last-second winner, Howard gets first tourney win
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Mar 18 • 10:22 AM EDT • Sports • sports.yahoo.com
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BrightSpring Health (BTSG) Climbs 7.8% on Double-Digit Growth Outlook

BrightSpring Health Services Inc. (NASDAQ:BTSG) is one of the 10 Stocks That Made Millionaires Today. BrightSpring rallied for a second day on Tuesday, jumping 7.81 percent to finish at $42.10 apiece, as investors welcomed the company’s reaffirmed growth outlook for this year. In a shareholders’ meeting on the same day, BrightSpring Health Services Inc. (NASDAQ:BTSG) […]

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Mar 18 • 2:50 AM EDT • Health • finance.yahoo.com
Let the Madness begin: Texas beats NC State on Tramon Mark's game-winner with 1 second left
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Mar 18 • 12:56 AM EDT • Sports • sports.yahoo.com
Observations after Sixers start trip with lopsided loss to Nuggets

The Sixers trailed by 33 points during the second quarter of their loss Tuesday night to the Nuggets.

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Mar 18 • 12:34 AM EDT • Sports • nbcsportsphiladelphia.com
First Four: Texas beats NC State after Tramon Mark's game-winner with 1 second left
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Mar 18 • 12:29 AM EDT • Sports • sports.yahoo.com
March Madness bracket updates: Texas tops NC State on last-second winner; Howard gets first tourney win
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Mar 18 • 12:13 AM EDT • Sports • sports.yahoo.com
Juliana Stratton wins Democratic primary, set to become Illinois’ second Black woman senator

Lt. Gov. Juliana Stratton is all but certain to make history, becoming one of three Black women to serve in the Senate at the same time.

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Mar 17 • 10:21 PM EDT • Politics • 19thnews.org
NASCAR driver Daniel Dye suspended for David Malukas comments

The Kaulig Racing driver will be suspended indefinitely for the second time in the last four years for comments he made about an IndyCar driver.

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Mar 17 • 9:01 PM EDT • Sports • sports.yahoo.com
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😐 Neutral (8%)
angry
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Oscar ratings fall 9% in Conan O’Brien’s second year hosting

The 98th Oscars hosted by Conan O'Brien saw a dip in ratings after several years of gains. The Walt Disney Co. on Tuesday said that just under 17.9 million viewers tuned into Sunday’s show, which air...

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Mar 17 • 8:09 PM EDT • Entertainment • yahoo.com
Orange Bank & Trust Company Celebrates Women’s Leadership at Annual Bronx Women in Business Event

MIDDLETOWN, N.Y., March 17, 2026 (GLOBE NEWSWIRE) -- Orange Bank & Trust Company proudly hosted its second annual Bronx Women in Business ev...

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Mar 17 • 4:00 PM EDT • Business • markets.businessinsider.com
Orange Bank & Trust Company Celebrates Women’s Leadership at Annual Bronx Women in Business Event

MIDDLETOWN, N.Y., March 17, 2026 (GLOBE NEWSWIRE) -- Orange Bank & Trust Company proudly hosted its second annual Bronx Women in Business event recently, an initiative created to celebrate the achievements, resilience, and leadership of women throughout the Bronx business community. Founded by Vanessa Baijnauth, Branch Manager of the Bank’s Williamsbridge Road office, along with the dedicated Bronx Women in Business Committee, the event continues to serve as a dynamic platform for empowering wom

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Mar 17 • 3:00 PM EDT • Business • finance.yahoo.com
The Gemini for Home voice assistant is now more concise, faster, & better at alarms/timers

Google is back with a second big update to Gemini for Home this month that notably improves the voice assistant.

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Mar 17 • 2:25 PM EDT • Technology • 9to5google.com
'Probably the softest second booking I can remember seeing'

Who does not love a trip down to London? This felt like a fantastic opportunity for us to close the gap on Crystal Palace and pick up three points that some of the teams around us in the relegation fight failed to get. Fair play to West Ham for taking a point off Manchester City - although, if I am being honest, I would have preferred they did not.

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Mar 17 • 8:01 AM EDT • Sports • sports.yahoo.com
'Dragon Mama' review: Part two of Sara Porkalob's Filipina family saga

Writer-performer Sara Porkalob continues her Dragon Cycle trilogy with the Los Angeles premiere of "Dragon Mama," the second installment of the family epic centered on Filipina mothers taking survival into their own hands.

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Mar 17 • 6:00 AM EDT • Entertainment • latimes.com
Japan's Idemitsu to invest $500 million in Australian Midocean to enter LNG business

Idemitsu Kosan , Japan's second-biggest oil refiner, said on Tuesday it ​will invest $500 million in Australia's ‌MidOcean Energy as part of a move towards a full-scale entry into the LNG ​business.

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Mar 17 • 5:26 AM EDT • Business • reuters.com
Tekken 8 Season 3 patch notes

It's already been more than two years since Tekken 8 released, and the game is getting its second major overhaul now.Bandai Namco has now released the official patch notes for the big Season 3 update coming tonight.

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Mar 16 • 7:53 PM EDT • Technology • eventhubs.com
Kennedy Center votes to shut down operations for 2 years and names a new president

The widely expected decision comes in the wake of numerous resignations and cancellations during President Donald Trump's second term, although Trump himself has cited the need for repairs as a reason for the closure.

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Mar 16 • 4:38 PM EDT • Politics • pbs.org
🙂 Positive (35%)
Pritzker flexes political muscle in Illinois Senate primary as 2028 buzz builds

Illinois primary could make history as three candidates vie for Durbin's Senate seat, with potential for second Black woman or Indian American senator.

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Mar 16 • 2:19 PM EDT • Politics • foxnews.com
2026 NFL offseason team grades: Rams earn high mark, while Broncos, Jaguars confuse

A report card for all 32 teams as we enter the second week of the 2026 NFL league year

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Mar 16 • 12:22 PM EDT • Sports • cbssports.com
Iran’s attacks have collapsed, and the trend is ‘overwhelmingly positive,’ analysts say. But the military side is separate from politics and markets

Iranian drone attacks on the United Arab Emirates collapsed from 332 on the second day of the war to just six on Sunday, according to the Institute for the Study of War.

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Mar 16 • 12:09 PM EDT • Politics • fortune.com
Alabama star Aden Holloway arrested before NCAA Tournament on drug charge

What we know about the Crimson Tide's second-leading scorer and what happened

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Mar 16 • 11:42 AM EDT • Sports • cbssports.com
TNT Sports to Debut '4.7 Seconds to the Championship' Tonight

Special project to highlight classic 2016 NCAA Final

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Mar 16 • 10:12 AM EDT • Sports • villanova.com