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Results for " gator " 534 found 🔀 AI-powered Shuffle

How deep does Auburn’s hatred of Alabama go? Check the Gatorade

Don’t go to Auburn for a taste of fruit punch. “We don’t even have red Gatorade." That's the Iron Bowl for you.

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May 4 • 4:20 AM EDT • Sports • usatoday.com
Investigation into fire at USF St. Pete Marine Science Lab | FOX 13 Tampa Bay

Investigators are still trying to determine the cause of the 2-alarm fire Saturday evening at the USF St. Pete campus. FOX 13's Heather Healy reports.

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May 3 • 6:17 PM EDT • Science • fox13news.com
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Gatorade getting a rebrand targeting non-athletes

Sixty years after it invented sports drinks, Gatorade is making a surprising pivot: It’s no longer focusing primarily on athletes. PepsiCo, Gatorade’s parent company, says the brand wants to broaden

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May 3 • 2:00 AM EDT • Business • telegraphherald.com
Person found dead in car after it plows into health club in Portland, Oregon

Investigators find explosives in car, which crashed into Multnomah Athletic Club shortly before 3am Saturday

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May 2 • 6:38 PM EDT • Health • theguardian.com
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Corruption, politics, and a former FBI agent: Lorain County ‘s government scandal explained

The Lorain County Sheriff's public corruption unit raided multiple county facilities — and a key investigator's identity suggests this is no political stunt.

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May 1 • 2:30 PM EDT • Politics • cleveland.com
House passes Corrections Dept. health bill with FOI restrictions

Read More at Inside Investigator >>

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May 1 • 7:45 AM EDT • Health • insideinvestigator.org
Instagram cracks down on content aggregators

The update targets content aggregators that don't post original content and instead simply re-upload others' posts.

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Apr 30 • 8:00 AM EDT • Technology • techcrunch.com
Justice Department rolls back gun control measures days after Trump assassination attempt

Days after a gunman charged security at the White House Correspondents’ Dinner in what investigators say was an attempt to kill President Donald Trump with legally owned firearms, his Justice Department is further rolling back gun control measures.

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Apr 29 • 3:24 PM EDT • Politics • cnn.com
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'Lifestyle analysis' found Moorhead business owner hid income while collecting SNAP

A Minnesota business owner is facing several felony charges after investigators say she filed false tax returns while fraudulently receiving SNAP benefits.

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Apr 28 • 9:22 PM EDT • Business • fox9.com
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Neuroinfectious Diseases Research Workshop: Advancing Translational Science and Clinical Innovation

The Neuroinfectious Diseases Research Workshop will be a two-day scientific meeting designed to accelerate research, foster collaboration, and build capacity in the field of neurological infections. Hosted at the NIH Neuroscience Center (NSC, Executive Boulevard), this meeting will bring together clinician-scientists, laboratory investigators, translational researchers, government partners, and trainees committed to advancing understanding of neuroinfectious

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Apr 28 • 8:00 AM EDT • Science • ninds.nih.gov
Mail-In test for colorectal cancer could help community health centers increase screening

Colorectal cancer (CRC) is the second most common cause of cancer death in the United States and disproportionally impacts people who receive care in under-resourced settings. Fortunately, several effective screening tests are available to detect cancer early when it is most treatable. In partnership with community health centers (CHC), investigators from Mass General Brigham and UCLA Health mailed one of two stool-based screening tests to more than 5,000 participants from CHCs in Boston and Los Angeles. Researchers found that participants were more likely to complete screening if they received a newer stool-based screening test, but follow-up colonoscopy rates remained low for those with abnormal results. Findings are published in JAMA Internal Medicine.

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Apr 28 • 8:00 AM EDT • Health • uclahealth.org
Dem pollster says party should do more to sell health care message

Focus groups conducted by Democratic-aligned firm Navigator Research show voters are struggling with health care costs, but some blame both parties.

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Apr 28 • 5:45 AM EDT • Health • politico.com
Investigators Seeking Attacker’s Motive Comb Through an Archive of Posts

Federal authorities are looking into whether Cole Tomas Allen posted on Bluesky as “coldforce,” who wrote and promoted liberal views that did not stand out on the left-leaning platform.

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Apr 27 • 7:11 PM EDT • Politics • nytimes.com
Florida lands Peyton Miller, No. 1 center in 2027 recruiting class

The Florida Gators continued their momentum on the high school recruiting trail with a commitment from Peyton Miller, ESPN's No. 1 center in the Class of 2027.

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Apr 27 • 3:39 PM EDT • Sports • espn.com
Puff, pass and publish: the science behind cannabis

As cannabis becomes more accepted across the United States, public conversations are changing quickly. But according to Rebecca Cooney, a professor of Strategic Communication at WSU, many people still misunderstand what cannabis research is actually about. Cooney works in the Edward R. Murrow College of Communication and is also a co-investigator with the Resource Center...

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Apr 26 • 10:37 PM EDT • Science • dailyevergreen.com
Hellish conditions, damaging delays and uncertain justice fuel mental health crisis in SC jails

Hundreds of mentally ill people are languishing for months in South Carolina jails, deprived of needed treatment in a legal purgatory that feeds a cycle of incarceration, despair and avoidable deaths, a Post and Courier investigation has found.

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Apr 26 • 5:00 AM EDT • Health • postandcourier.com
In-state WR target commits to SEC program over FSU

The Florida State Seminoles missed out on in-state wide receiver Anthony Jennings, who has committed to the Florida Gators.

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Apr 25 • 5:17 PM EDT • Sports • sports.yahoo.com
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Mohammad Saleem receives Young Investigator Award

The award recognizes individuals who demonstrate “outstanding promise” in physiological sciences research.

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Apr 25 • 2:05 PM EDT • Health • news.vumc.org
‘Fight federal overreach’: Delaware appeals federal judge’s order to surrender wage records for 15 businesses to ICE investigators

Federal authorities say they have received tips that the businesses are illegally hiring undocumented immigrants.

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Apr 24 • 11:03 AM EDT • Business • whyy.org
Newer testing methods suggest significant silent spread of measles in the US, threatening elimination

Investigators estimated that an outbreak along the Arizona/Utah state line has been at least 6.5 times larger than the number of known cases.

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Apr 24 • 7:00 AM EDT • Health • cnn.com
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Man shot outside sports bar in Philadelphia's Frankford section

Investigators say more than a dozen shots were fired, and the victim was hit six times.

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Apr 24 • 6:15 AM EDT • Sports • 6abc.com
Critical Access Toolkit for Substance Use Disorder

The toolkit produced by PHI's Bridge program was developed by experts in addiction medicine. It provides educational videos and downloadable resources on need-to-know information about critical access to medications for opioid use disorder and overdose prevention tactics.

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Apr 23 • 2:30 PM EDT • Health • phi.org
ROSES-25 A.11 Early Career Investigator Program in Earth Science Correction

ROSES-25 A.11 Early Career Investigator Program (ECIP) in Earth Science supports outstanding scientific research and career development of scientists and

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Apr 23 • 11:18 AM EDT • Science • science.nasa.gov
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Leading with heart: Juan Salazar’s mission to advance pediatric health care for all children

An internationally recognized pediatric infectious diseases specialist and investigator, Salazar brings decades of leadership and experience to Vanderbilt Health.

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Apr 21 • 10:09 AM EDT • Health • news.vumc.org
Cohen & Gresser Welcomes Leading Entertainment Litigator Jeffrey M. Movit as Partner

/PRNewswire/ -- Cohen & Gresser is pleased to welcome Jeffrey M. Movit as a partner in its Litigation & Arbitration group, based in New York and Palo Alto. He...

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Apr 21 • 10:09 AM EDT • Entertainment • prnewswire.com
Daytime napping patterns may reveal hidden health decline in older adults

New research reveals that as people age, naps may be an easily trackable warning sign of underlying conditions or declining health. A new study by investigators from Mass General Brigham and Rush University ...

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Apr 20 • 11:40 AM EDT • Health • medicalxpress.com
New government-run health plan proposed, as businesses snubbed again

Read More at Inside Investigator >>

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Apr 20 • 7:45 AM EDT • Health • insideinvestigator.org
KitKat, Gatorade or granola bars? What’s banned under new SNAP rules are mixed.

Many GOP states are enacting soda and candy bans for food stamp purchases amid MAHA’s healthy food efforts. Some retailers and SNAP users find the new rules complicated.

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Apr 20 • 5:00 AM EDT • Health • washingtonpost.com
CKD Screening With Mobile Health Units Reveals Disparities

Study investigator, Phillip Levy, MD, discusses the reality of how a zip code can impact CKD risk and treatment options.

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Apr 18 • 12:54 PM EDT • Health • hcplive.com
Amendment 53: New Opportunity: Early Career Investigator Program in Earth Science

ROSES-2025 Amendment 53 releases A.11 ECIP as a new opportunity in ROSES-25. Mandatory Notices of Intent are due by May 18, 2026, and proposals are due June 17, 2026.

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Apr 17 • 10:08 AM EDT • Science • science.nasa.gov
Gatorade, inventor of the sports drink, is getting a rebrand targeting non-athletes

Sixty years after it invented sports drinks, Gatorade is making a surprising pivot: It's no longer focusing primarily on athletes.

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Apr 16 • 12:39 PM EDT • Sports • ksl.com
Gatorade, inventor of the sports drink, is getting a rebrand targeting non-athletes

Sixty years after it invented sports drinks, Gatorade is making a surprising pivot: It’s no longer focusing primarily on athletes.

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Apr 16 • 10:30 AM EDT • Sports • wlrn.org
Gatorade, inventor of the sports drink, is getting a rebrand targeting non-athletes

Sixty years after it invented sports drinks, Gatorade is making a surprising pivot: It’s no longer focusing primarily on athletes.

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Apr 16 • 7:43 AM EDT • Sports • wral.com
La. Senate panel OKs bill to indoctrinate teens in conservative 'success' ideology

Two Black Democrats on the committee, Katrina Jackson-Andrews and Sidney Barthelemy II, objected to naming the bill after far-right activist Charlie Kirk, who had a history of publicly making racist and other derogatory comments.

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Apr 15 • 5:27 PM EDT • Politics • nola.com
Maximum-security KY prison neared riot over guard planting contraband on inmates

Investigators say an officer who “discovered” contraband secretly planted it.

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Apr 15 • 5:15 AM EDT • Politics • kentucky.com
Nevada investigators: Man defrauded Las Vegas sports betting investors

Investigators in Nevada allege a man defrauded investors out of tens of thousands of dollars as part of a Las Vegas sports betting scheme, the 8 News Now Investigators have learned.

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Apr 13 • 3:08 PM EDT • Sports • 8newsnow.com
Artificial sweeteners: Why the science war is raging on

Conflicting studies on artificial sweeteners are fuelling fresh debate across food and drink, as health risks, regulation and reformulation collide worldwide.

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Apr 13 • 5:07 AM EDT • Science • foodnavigator.com
Community rallies around local business after fire

Investigators are trying to find out what set off a massive fire that tore through a lumber business in Wayne County.

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Apr 12 • 9:17 PM EDT • Business • fox8.com
Franklin youth sports event fight; gunfire reported, man arrested

Franklin police arrested a 36-year-old Illinois man on Sunday after a youth sports fight prompted gunshot reports, but investigators say no gun was fired.

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Apr 12 • 7:26 PM EDT • Sports • fox6now.com
Nancy Guthrie Update: Expert Names ‘Most Likely’ Source of Suspect’s DNA

DNA is ‘hardy,’ says CeCe Moore, and one source might be investigators’ best hope at learning what happened to Nancy Guthrie.

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Apr 12 • 12:42 PM EDT • Entertainment • cbs19news.com
Nancy Guthrie Update: Expert Names ‘Most Likely’ Source of Suspect’s DNA

DNA is ‘hardy,’ says CeCe Moore, and one source might be investigators’ best hope at learning what happened to Nancy Guthrie.

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Apr 12 • 12:42 PM EDT • Entertainment • yakimaherald.com
Variety’s 2026 Legal Impact Report: Hollywood’s Top Attorneys

Meet Hollywood's top entertainment dealmakers and litigators of 2026.

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Apr 8 • 11:00 AM EDT • Entertainment • variety.com
Nancy Guthrie Kidnappers Likely Made This Fatal Mistake, Says Investigator

The 84-year-old mom of Savannah Guthrie has been missing for ten weeks.

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Apr 8 • 10:37 AM EDT • Entertainment • kten.com
Nancy Guthrie Kidnappers Likely Made This Fatal Mistake, Says Investigator

The 84-year-old mom of Savannah Guthrie has been missing for ten weeks.

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Apr 8 • 10:37 AM EDT • Entertainment • wyomingnewsnow.tv
Health Law Navigator: The Compliance Department vs. The Machines: A Playbook for Using AI

In 2026, health care facilities are under relentless pressure to use AI. From diagnostic algorithms that outperform radiologists to predictive

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Apr 6 • 12:58 PM EDT • Health • spencerfane.com
Saturday stop in Swamp boosts Florida in Andrew Beard's recruitment

After a visit with Florida in the Swamp on Saturday, 4-star running back Andrew Beard is becoming more bullish on the Gators.

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Apr 5 • 2:31 PM EDT • Sports • sports.yahoo.com
Ben Shelton suffers another early exit at ATP Houston 250

Ben Shelton suffered another upset loss in Houston, falling as the top seed in the quarter-finals. He's still alive in doubles action, however.

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Apr 4 • 7:29 PM EDT • Sports • sports.yahoo.com
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Bucks reportedly told NBA investigators that Giannis Antetokounmpo declined to scrimmage 3-on-3 as part of return-to-play protocol
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Apr 4 • 1:38 PM EDT • Sports • sports.yahoo.com
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How the Internet Became the ‘Cookbook’ of the Drug Trade

A baffling overdose death took investigators to the frontier of ultra-potent synthetic drugs. The clues were hauntingly familiar.

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Mar 31 • 5:00 AM EDT • Science • nytimes.com
Sacramento’s Sutter Health settles feds’ drug violations probe at two facilities

Investigators found hundreds of violations at Sutter Medical Center in Sacramento and a surgical center in Fairfield.

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Mar 30 • 5:49 PM EDT • Health • sacbee.com
Florida influencer Clavicular arrested on suspicion of battery

A controversial manosphere influencer who goes by the name Clavicular was arrested on suspicion of battery, and no, this had nothing to do with the alligator incident.

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Mar 28 • 1:07 PM EDT • Entertainment • latimes.com
Florida football hosting key recruits this weekend for spring visits

Florida football hosts top recruits for a key March visit weekend that could have major effects on the Gators' first class under Jon Sumrall.

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Mar 28 • 9:49 AM EDT • Sports • sports.yahoo.com
Jaouadi sets record as Florida, Indiana co-lead NCAA swim

Florida freshman Ahmed Jaouadi broke the NCAA record in the 1,650-yard freestyle, and the Gators shared the Day 1 lead with Indiana at the Division I swimming and diving championships on Wednesday.

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Mar 25 • 11:54 PM EDT • Sports • espn.com
‘Swamp People’: Don Brewer & Calum Landry Capture Giant Legendary Gator

Plus, Troy Landry takes his 81-year-old mom out on the water.

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Mar 25 • 9:00 PM EDT • Entertainment • cbs19news.com
Special Battleground Report on Food and Health Part II: Messages

This Navigator Research report covers messaging guidance to effectively communicate on food and health-related issues to Americans in the battleground.

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Mar 24 • 4:45 AM EDT • Health • navigatorresearch.org
Your Thymus and Your Healthspan

Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.

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Mar 22 • 2:18 PM EDT • Health • erictopol.substack.com
Florida GOP’s divisions, cancel culture and Alligator Alcatraz: IFP

Turns out Florida state lawmakers can't approve budget, but they do like cancel culture. And how much has the state spent on Alligator Alcatraz?

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Mar 19 • 2:50 PM EDT • Politics • usatoday.com
NCAA Tournament 2026 bracket picks, upsets, plus Cinderella teams: Model simulates March Madness 10K times

SportsLine's college basketball model has called 25 first-round NCAA Tournament upsets by double-digit seeds

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Mar 18 • 2:47 PM EDT • Sports • cbssports.com
A milestone voyage for Antarctic science

Navigating monolithic icebergs, massive ocean waves and sub-zero snowstorms, CSIRO research vessel (RV) Investigator is a workhorse for Antarctic science. In just over 11 years and spread across seven voyages, the vessel ...

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Mar 17 • 9:57 PM EDT • Science • phys.org
A milestone voyage for Antarctic science

Navigating monolithic icebergs, massive ocean waves and sub-zero snowstorms, CSIRO research vessel (RV) Investigator is a workhorse for Antarctic science. In just over 11 years and spread across seven ...

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Mar 16 • 10:00 PM EDT • Science • phys.org
DEA seizes $300K during search warrant at West LA business

Investigators seized approximately $300,000 in cash and halted the sale of marijuana and vape products.

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Mar 15 • 1:06 AM EDT • Business • nbclosangeles.com
Georgia lawmakers grill former special prosecutor Nathan Wade over Trump election case

State senators on Friday grilled the former special prosecutor who led the Georgia election interference case against President Donald Trump about communications his team had with federal investigators. But their efforts were largely frustrated by his repeated assertions that he couldn't remember details.

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Mar 13 • 7:57 PM EDT • Politics • pbs.org
🙂 Positive (35%)
Legislators reject Flock’s first political donations in California

Campaign representatives for two Democratic lawmakers said they'd return the money amid concerns that Flock’s data could be accessed by ICE investigators.

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Mar 13 • 9:00 AM EDT • Politics • politico.com
Freak accident blamed for fire that heavily damaged Bucks County business

Fire tore through an industrial building in Bucks County after what investigators are calling a freak accident.

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Mar 13 • 7:43 AM EDT • Business • 6abc.com
Student Led Service Group Helps Refugees Navigate Healthcare System

UW Medical Students Helps Refugees Navigate Healthcare System

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Mar 11 • 3:52 PM EDT • Health • gonzaga.edu
Science Shorts: Rice for weight control, functional dairy tech and more

Rice for weight control, functional dairy tech and more feature in this edition of Science Shorts

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Mar 11 • 2:13 AM EDT • Science • foodnavigator-asia.com
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Ed Martin, outspoken Justice Department lawyer, is formally accused of ethical violations

Ed Martin, an outspoken Trump administration official, is facing attorney discipline proceedings in Washington, DC, for a letter he sent to Georgetown Law about its diversity programs, the district’s professional conduct investigator announced on Tuesday.

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Mar 10 • 9:43 AM EDT • Politics • cnn.com
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Traditional Pacific navigators bring the intricate science of

Organized by Sophia Perez, Indigenous Technologies Coordinator for the Berkeley Center for New Media, a weeklong series of public workshops beginning March 9 will feature master navigators teaching

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Mar 10 • 8:52 AM EDT • Science • ls.berkeley.edu
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Traditional Pacific navigators bring the intricate science of wayfinding to the Bay Area

Organized by Sophia Perez, Indigenous Technology Coordinator for the Berkeley Center for New Media, a weeklong series of public workshops beginning March 9 will feature master navigators teaching everything from traditional canoe technology to ancient star-mapping.

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Mar 9 • 8:18 PM EDT • Science • news.berkeley.edu
USA TODAY Sports Network 2026 All-SEC men's basketball awards, player of the year

Darius Acuff Jr. and the Florida Gators took home major honors in the USA TODAY Sports Network's All-SEC awards. Check out the full selections.

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Mar 9 • 12:00 PM EDT • Sports • tennessean.com
Florida women's basketball defeat MSU in SEC Tournament opener

The Lady Gators led for all but 45 seconds in Florida's Round 1 SEC Tournament win over the Mississippi State Bulldogs.

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Mar 4 • 10:10 PM EST • Sports • sports.yahoo.com
Teeth smaller than a fingertip reveal the first primate ancestor

Tiny, tooth-sized fossils have just reshaped the story of our deepest ancestry. Paleontologists have discovered the southernmost remains ever found of Purgatorius—the earliest-known relative of all primates, including humans—in Colorado’s Denver Basin. Previously thought to be confined to Montana and parts of Canada, this shrew-sized, tree-dwelling mammal now appears to have spread southward soon after the asteroid impact that wiped out the dinosaurs.

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Mar 2 • 7:00 PM EST • Science • sciencedaily.com
Pokopia Becomes Highest-Rated Pokémon Game On Metacritic

Pokémon Pokopia has surpassed Pokémon Y to become the most highly recommended Pokémon game ever, according to the aggregator

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Mar 2 • 11:30 AM EST • Technology • kotaku.com
Winner and Loser of the Week in Florida politics

FSU locks up their President for 3 more years, Dems pick a new future leader, and is the state on the hook for Alligator Alcatraz costs after all?

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Mar 1 • 5:30 AM EST • Politics • floridapolitics.com
How to turn your side hustle into a business

Gig work can boost your income, but it can also create new money problems if you’re not planning ahead. Consumer Investigator Rachel DePompa shares how to treat your side hustle like a business and make it work for you.

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Feb 26 • 2:49 PM EST • Business • foxcarolina.com
'Stop laughing.' Abby Wambach, more athletes condemn Trump's hockey comments

Retired soccer players Abby Wambach and Julie Foudy said they wish the men's hockey team would have rejected Trump's offer to visit the White House.

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Feb 26 • 11:34 AM EST • Sports • usatoday.com
Bracketology: Florida, Virginia moving up while Auburn, Indiana slide in NCAA Tournament projection

Breaking down who is trending up and who is trending down in CBS Sports Bracketology

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Feb 26 • 10:51 AM EST • Sports • cbssports.com
Stop taking free flights while out sick, union tells airline workers

The AFA chapter for Endeavor Air, a Delta subsidiary, told members it had seen more investigatory meetings for pass travel violations.

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Feb 25 • 8:39 AM EST • Business • businessinsider.com
Woman killed in UIC lot was on way to appointment with infant; suspect found dead: investigators

The person accused of fatally shooting a woman with a baby in a West Side hospital parking garage earlier this month was found dead, officials said.

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Feb 21 • 8:42 AM EST • Health • abc7chicago.com
Schubert Biochemistry Lab Advances Science and Patient Care

The Schubert Research Clinic Biochemistry Laboratory plays a critical role in supporting investigators by delivering high-quality clinical and research assays that move science—and patient care—forward.

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Feb 20 • 4:25 PM EST • Science • scienceblog.cincinnatichildrens.org
College basketball power rankings: Florida up to No. 2, just behind Michigan

The Wolverines, the national title favorite, and the Gators, the reigning national champs, lead the Power Rankings

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Feb 20 • 3:28 PM EST • Sports • cbssports.com
Top 25 And 1:

The Gators are 11-1 in their last 12 games after beating South Carolina on Tuesday

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Feb 18 • 2:30 PM EST • Sports • cbssports.com
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Woman who impersonated orthodontist at Raleigh business was part of months-long investigation

Investigators with the North Carolina Dental Board and Raleigh police have looked into the allegations against Ebony McBean for months. Their analysis found that McBean portrayed herself as an orthodontist and performed work that she wasn't licensed to do.

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Feb 16 • 12:39 PM EST • Business • wral.com
The Sports Report: Strickland looking to recapture more Gainesville magic

In addition to his two world titles, Jeff Strickland has six Gatornationals victories in Stock and Top Dragster and he’s set to return this season looking to add to that total.

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Feb 13 • 7:00 AM EST • Sports • nhra.com
CA sues Trump over public health funds

The Trump administration has ordered the CDC to rescind public health funds from California. Now the state is suing to block the clawback.

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Feb 12 • 9:00 AM EST • Health • calmatters.org
California sues as Trump cuts $600M in public health grants to four states

California, Colorado, Illinois and Minnesota argue the cuts are politically motivated and would harm HIV programs, emergency preparedness and more.

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Feb 12 • 8:30 AM EST • Health • calmatters.org
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CFO of Clearwater business laundered $2.4 million, police say

Jeffery Crane, 47, stole from companies in other parts of Florida and Georgia, according to investigators.

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Feb 11 • 5:38 PM EST • Business • tampabay.com
Investigators searching a location in Arizona in disappearance of Nancy Guthrie

Officials say a person has been detained for questioning in the disappearance of Nancy Guthrie. The Pima County Sheriff’s Department said in a statement Tuesday night that deputies detained someone

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Feb 11 • 4:07 AM EST • Entertainment • yakimaherald.com
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Curiosity Blog, Sols 4798-4803: Back for More Science

Written by Michelle Minitti, MAHLI Deputy Principal Investigator

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Feb 10 • 1:47 PM EST • Science • science.nasa.gov
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A Grip on Sports: Now that the NFL season is in the rearview mirror (though there is still one massive party to attend) it's time to shift the focus a bit

A GRIP ON SPORTS • It’s transition time. And we are not referring to the weather, despite the presence of Gatorade showers Sunday night.

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Feb 10 • 3:23 AM EST • Sports • spokesman.com
Former Dodgers star Yasiel Puig convicted of federal charges in sports betting case

Former Dodger Yasiel Puig was found guilty of lying to investigators about his involvement in illegal sports betting and obstructing justice.

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Feb 6 • 7:43 PM EST • Sports • abc7.com
QB competition imminent says Florida football OC Buster Faulkner

Buster Faulkner opens Florida’s QB battle, vowing to build the offense around whoever wins the job this spring.

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Feb 1 • 10:35 AM EST • Sports • gatorswire.usatoday.com
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Where Florida football's 2026 signees land in Rivals300 final update

Rivals300 updated its rankings for the final time this week as the class of 2026 recruiting cycle closes. Here's where Florida Gators signees stand.

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Jan 31 • 6:05 AM EST • Sports • gatorswire.usatoday.com
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Is Wyoming hoops stuck in purgatory within modern college basketball?

Every season for a reasonably successful mid-major university begins in a similar fashion. They schedule a few in-state cupcakes as the season and home openers before, if they are lucky enough, participating in an ever-declining MTE tournament during the week of Thanksgiving. Throw in a dash of high-major money labeled as “buy games” to help […]

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Jan 28 • 10:00 AM EST • Sports • mwcconnection.com
UConn Health Postdoc a Projected Top-10 Draft Pick

Grant for Emilie Korchak as part of Uplifting Athletes’ 2026 Young Investigator Draft Class

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Jan 27 • 7:15 AM EST • Health • today.uconn.edu
Vikings 2026 Outlook: Trade Addison? Fix O-Line? QB Purgatory

Addison trade rumors heat up, Flores stays, QB crisis grows—Vikings 2026 outlook unpacked.

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Jan 26 • 9:58 AM EST • Sports • dailynorseman.com
D.H.S. Cited Foreign Students’ Writings and Protests Before Their Arrests

Documents unsealed by a federal judge on Thursday include dossiers that investigators prepared on pro-Palestinian student activists before they were targeted for deportation.

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Jan 22 • 11:37 PM EST • Politics • nytimes.com
Basha star repeats as Gatorade Girls Cross Country Player of the Year

For the second consecutive year, Chandler Basha's Taylor Drewry is the Arizona Gatorade Girls Cross Country Player of the Year for 2025-26.

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Jan 22 • 3:16 PM EST • Sports • azcentral.com
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Ex-Dodger Yasiel Puig heads to trial in sports betting case

Former MLB star Yasiel Puig's federal trial begins in Los Angeles on Tuesday. The former Dodger faces charges of obstruction and lying to investigators about an illegal sports betting ring.

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Jan 20 • 10:47 AM EST • Sports • foxla.com
‘Smearing the victim’: Minnesota’s attorney general accuses federal investigators of maligning Renee good

Minnesota Attorney General Keith Ellison reacts to reports that the DOJ is investigating Renee Good’s possible ties to activist groups following her death. He says her background is “irrelevant” to the case and that it is an attempt to smear the victim.

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Jan 12 • 11:40 PM EST • Politics • cnn.com
😐 Neutral (0%)