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New cholesterol guidelines could change when you get tested
A major new U.S. cholesterol guideline is shifting the focus toward earlier, more personalized prevention of heart disease. It urges people to start screening sooner—sometimes even in childhood—and highlights the importance of tracking not just LDL (“bad”) cholesterol but also genetic risk factors like lipoprotein(a). A new, more advanced risk calculator now uses broader health data to better predict heart attack and stroke risk over decades.
Last xAI cofounder, Ross Nordeen, leaves as Musk preps for SpaceX IPO
Elon Musk is shaking up xAI ahead of the SpaceX IPO. All 11 of his cofounders are gone, 8 of them since January.
CBS Sports offers split decision on Iowa vs. Nebraska Sweet 16
With tipoff coming later today, CBS Sports offered a split decision on who win between Iowa and Nebraska in the Sweet 16.
Ipswich paramedic died after struggling with her mental health
A coroner says Rebecca McLellan, from Ipswich, struggled after her bipolar disorder diagnosis.
OpenAI pivots from consumer hype to business reality
The company that started the consumer AI craze is clearing the decks for an IPO.
Grifols Plans IPO of U.S. Biopharma Business
The Spanish pharmaceutical company is looking to raise money to bolster its balance sheet and fund investments.
24 new deep-sea species found including a rare new branch of life
In a remarkable deep-sea breakthrough, researchers have discovered 24 new species of amphipods in the Pacific’s Clarion-Clipperton Zone—including a rare, entirely new superfamily. The findings reveal previously unknown branches of life and push the boundaries of how deep these creatures are known to live.
Grifols approves IPO of its US biopharma business
Healthcare company Grifols said on Tuesday it has approved a U.S. initial public offering of its U.S. biopharma business.
Health Ring Oura Interviews Banks for IPO as Soon as This Year
Health ring Oura has been interviewing bankers to advise on an initial public offering that could take place as soon as this year, according to a person with direct knowledge of discussions. A public offering would follow fast growth at the company, which sells connected devices—which cost from ...
Ambani's Reliance Jio: businesses and investors of the IPO-bound firm
Indian billionaire Mukesh Ambani's Reliance Jio Platforms is gearing up to file papers seeking regulatory approvals for a Mumbai listing, in what is likely to be the biggest-ever stock offering in the country.
‘We’ve got some unfinished business’: Corey Gipson reflects on historic Austin Peay season
Austin Peay men's basketball head coach Corey Gipson recently reflected on his 2025-26 season and revealed what makes Clarksville special.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Brooks Nader, 29, Reveals She Had Liposuction ‘Years Ago’ and Regrets It: ‘I Just Didn’t Need It’ (Exclusive)
The model and reality star tells PEOPLE that she experienced unwanted side effects from the procedure
Nuclear reactor developer X‑energy files for US IPO
X-energy has filed for an initial public offering in the United States, it said on Friday, as the reactor developer aims to tap growing investor enthusiasm for nuclear power.
Figma's stock drops 11% in two days after Google releases 'vibe design' product
Figma's stock has been getting hammered on concerns about AI, and Google's new design product is adding to that anxiety.
Canadian province poaches over 400 U.S. health workers, eyes Oregon for more
Portland ranked among the top U.S. cities for the number of people visiting the British Columbia’s health careers website.
Dipoto details how Seattle Mariners unlocked Eduard Bazardo
Eduard Bazardo was an unheralded trade add in 2023, but he was a player the Seattle Mariners were excited to attain and make a few key adjustments with.
Altman, Amodei and Musk fight dirty for the biggest prize in business
OpenAI, Anthropic and SpaceX plan initial public offerings that could raise sums equivalent to a decade of American IPOs, as artificial intelligence labs seek funding.
Mamdani addresses residents in third 'Rental Ripoff' hearing
This was the first time New York City housing residents were allowed inside.
Exclusive: Sword Health launches GLP-1 program as it eyes more deals
The company is weighing more M&A and an IPO as early as next year.
Cosmetic surgery investigation prompts push for tighter safety standards
A national plastic surgeons group urged people seeking liposuctions, Brazilian butt lifts or other cosmetic procedures to "do their homework."
Olaplex stock has plunged since its IPO. Here’s how the hair care brand is trying to turn itself around
Olaplex, a prestige hair care brand, has seen its sales and stock price plummet after a lawsuit. Now, the company is trying to turn its business around.
Science & Medicine: APOBECs and the fight against cancer
One of the handiest tools in our immune system is an enzyme called apolipoprotein B mRNA-editing enzyme, catalytic polypeptide — better known as APOBECs.
Police: Man arrested after trespassing at Wilton Manors business, loitering at private residence
A 53-year-old man was arrested Wednesday after he violated a no trespass order at a bar in Wilton Manors, authorities said.
'Everybody down!': BWC shows Austin officers stop mass shooting suspect in under a minute
Austin officers arrived within 56 seconds of the first 911 call, shooting and killing the suspect after he fired at police, Chief Lisa Davis said
Selena Gomez was 'misdiagnosed' before getting the correct mental health assessment
Selena Gomez has been open about her bipolar diagnosis, but it was a long road to understanding what was truly going on with her mental health.
Magic rout visiting Wizards behind Paolo Banchero’s 37 points
ORLANDO, Fla. — Entering Tuesday’s game against the Wizards, the Magic knew they’d already be without Franz Wagner, who is managing an extended rehab of a left high ankle sprain. Then, in the hours leading up to tipoff, Orlando learned it would also be without Anthony Black (right quad contusion) for the second game in a row and Wendell Carter Jr. (left ankle soreness) while hosting Washington ...
Bring On Defunct: The iPod Enthralls Young Music Listeners
It’s not exactly going analog, but people looking to move away from streaming say Apple’s old device is a small step away from constantly being online.
Analyst assesses Iran politics as US launches attacks
Terrorism expert Hans-Jakob Schindler describes Iran's leadership as a "multipolar system" that will be hard to break through.
Sunway Healthcare launches prospectus for up to $736 million IPO
Sunway Healthcare Holding on Friday launched the prospectus for its initial public offering that is expected to raise up to 2.86 billion ringgit ($735.98 million) in what could be Malaysia's largest listing in almost a decade.
She showed warnings of a failing behavioral health system in rural AZ. Her crisis turned deadly.
"She was failed by the system as much as society was." As Angela Bouck crossed the center line in a fatal 2025 crash, her history of bipolar disorder & lack of a mental competency evaluation reveals a breakdown in Arizona’s behavioral healthcare system.
Medtronic’s diabetes business MiniMed looks for $784m in US IPO
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Trump addresses health care costs, says ACA was "meant for the insurance companies"
Champions League Preview: Juventus vs. Galatasaray
Juventus face a monumental task of trying to reverse a 5-2 aggregate scoreline that was a lot of their own doing in Wednesday night’s second leg against Galatasaray.
How did Robert Carradine die? Disney star battled this disorder
"Lizzie McGuire" star Robert Carradine battled bipolar disorder for nearly two decades, his family said.
Why people are buying iPods again
Nostalgia and digital burnout are driving a new rush for Apple's retired iPods.
Inside xAI: Elon Musk is locked in for a big year for Grok, IPO
In the wake of cofounder exits, Elon Musk's hands-on management is reshaping the startup.
Candidate for Miss Connecticut shares her mental health and addiction struggles
At a glance, one may get a misguided perception of Christa Steiner. She’s a musician and candidate for Miss Connecticut. While the sash and crown are beautiful parts of Steiner, it’s her struggle that illustrates her story. She recognized the ugly pieces of addiction while living with an undiagnosed bipolar disorder. “When you have an untreated mental illness, self-medication is a big…
RFK Jr. claimed that keto diets cured schizophrenia. Here’s what science says.
Ketogenic diets do show promise for schizophrenia and bipolar disorder, but the research is preliminary and not backed by randomized controlled trials.
RFK Jr. claimed that keto diets cured schizophrenia. Here’s what science says.
Ketogenic diets do show promise for schizophrenia and bipolar disorder, but the research is preliminary and not backed by randomized controlled trials.
Zabit Magomedsharipov announces combat sports return 7 years after final UFC fight
One of MMA's biggest what-ifs is returning to combat sports competition.
"Therapy Thursdays" works to make mental health approachable for BIPOC communities
WEBTOON Entertainment (WBTN) Is Up 7.0% After Securities Fraud Case Proceeds Past Dismissal - Has The Bull Case Changed?
WEBTOON Entertainment is now facing an active securities fraud class action after a U.S. District Court in November 2025 denied its motion to dismiss allegations that it misled investors about Monthly Active Users at the time of its June 27, 2024 IPO. The court’s decision has prompted law firms to investigate potential breaches of fiduciary duty by WEBTOON’s officers and directors, raising fresh questions about its disclosure practices and governance controls. We’ll now examine how the...
Fintech Clear Street postpones US IPO, Bloomberg News reports
Wall Street broker Clear Street has postponed its U.S. initial public offering, Bloomberg News reported on Thursday, marking the second delayed listing in a week as the IPO market faces another bout of volatility.
Celebrating Women in Science Day 2026 at CERN
Every year, on 11 February, CERN celebrates the International Day of Women and Girls in Science. In an effort to amplify diverse voices in STEM, six women scientists from CERN open up about their careers and the lessons they hope to pass on to the next generation. Francesca is an Italian biomedical engineer pursuing her PhD at CERN, working in the robotics team of the Beams Department. She’s currently working on the MARCHESE project, in affiliation with Campus Bio-Medico University of Rome, focusing on contactless monitoring of physiological parameters. Despite choosing a scientific career and often volunteering in scientific outreach initiatives, Francesca continues to nurture her passion for the humanities and arts. “I firmly believe that collaboration and inclusion are the right paths to improve the world together. I’m driven by a strong curiosity about everything around me.” Berare is a Turkish experimental physicist who worked with the ATLAS experiment during her MSc and PhD on searches for physics beyond the Standard Model. During her PhD, she became a Support Scientist for the Beamline for Schools (BL4S) competition, which marked the beginning of her journey combining research with science communication. She now works for both BL4S and ELISA, the mini proton accelerator at CERN’s Science Gateway. She fondly remembers the moment when the BL4S 2022 winners arrived at the experimental zone: “I felt incredibly lucky to share my passion with young, curious and really passionate people. We spent two weeks of beam time together watching their ideas turn into reality. All the intricate details of running an experiment, we accomplished them as a team.” Mia is a Canadian research fellow in the Accelerator Systems Department, working on beam developments for fundamental physics with radioactive molecules. Mia pursued a bachelor’s degree in mechanical engineering before moving to Vancouver for a master’s degree in engineering physics. Her interest in radioactive ion beam production brought her to CERN, where she studied actinide beams for three years as a PhD student in the Marie Curie European Training network “LISA” (Laser Ionisation and Spectroscopy of Actinides) at ISOLDE – a facility at CERN where scientists study the properties of atomic nuclei, with further applications in fundamental studies, astrophysics, and material and life sciences. Laura is a German mechanical engineer at CERN working on research and development to produce cavities for future accelerators. She studied mechanical and aerospace engineering at the Technical University of Munich. She joined CERN four years ago as a technical student for her master’s thesis and continued as a fellow working on collimators. Laura says that “as a child, I took part in girls’ day initiatives, which sparked my fascination for astrophysics and engineering. Later, it felt natural for me to give something back by organising workshops for young students to make STEM seem less intimidating and more accessible.” She particularly enjoys being close to the CERN Main Workshop and understanding how design ideas become real components. Paraskevi is a Greek physicist working at CERN’s HiRadMat (High-Radiation to Materials) facility, designed to deliver high-intensity beams to an irradiation area where material samples, as well as accelerator component assemblies, can be tested. She studied physics at NKUA, specialising in nuclear and particle physics, and is now pursuing her PhD at HiRadMat in collaboration with the University of Liverpool, studying novel materials for high-intensity beam diagnostics. “Continuous learning is one of my biggest motivators, and I am looking forward to exploring the limits of our knowledge on beam-material interactions,” says Paraskevi. Silvia is a Spanish physicist and deputy project manager for the Muon Drift Tube of the CMS detector, a general-purpose detector at the Large Hadron Collider (LHC). She started her career at CERN more than 20 years ago as a technical student, working on prototypes of the first dipoles for the LHC. “My first motivation came in high school, from my teacher,” says Silvia about what made her pursue a career in STEM. “My favourite part about my job is learning. You can learn something new every day.” In parallel to this initiative, like every year since 2017, from 2 to 6 February 66 women scientists and engineers visited schools in Geneva, Switzerland, and in the Haute-Savoie and Ain regions of France to meet with students. Organised in collaboration with CERN, the University of Geneva, EPFL, LAPP and LAPTh, this event allowed more than 4200 students between 6 and 17 years old to meet a woman scientist, discuss their profession and career path, ask questions and participate in classroom activities.
Solace Health eyes IPO after $130M raise
Solace CEO Jeremy Gurewitz says the company is targeting an IPO in 2028.
Chipotle CEO allegedly suggests company would keep raising prices and 'lean into' customers making over $100K
Chipotle CEO allegedly suggested targeting customers earning over $100,000 per year in leaked audio, sparking controversy over potential price hikes.
Haiti’s transitional council hands power to US-backed prime minister
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Jennifer Garner reacts to Once Upon a Farm's eye-popping IPO
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Joby Aviation becomes newest partner of Sharks Sports & Entertainment
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Joby Aviation becomes newest partner of Sharks Sports & Entertainment
Sharks Sports & Entertainment (SSE) announced today a partnership that makes Joby Aviation a proud partner of the San Jose Sharks and naming partner on the new Reimagination Studio. As part of the collaboration, Sharks Sports & Entertainment will work exclusively with Joby Aviation to explore vertiport development in the
Musk joins his rocket and AI businesses into a single company before an expected IPO this year
NEW YORK (AP) — Elon Musk is joining his space exploration and artificial intelligence ventures into a single company before a massive planned initial public offering for the business later this year.
Musk joins his rocket and AI businesses into a single company before an expected IPO this year
Elon Musk is joining his space exploration and artificial intelligence ventures into a single company before a massive planned initial public offering for the business later this year.
The New Science of Craving
We often view our cravings—whether for drugs, alcohol, food, or approval—as indictments of our character. Yet neuroscience and psychology say otherwise; here's why.
City High Student of the Month presents at science fairs nationwide and started nonprofit to get science supplies in schools
Amal Eltayib started a nonprofit to benefit schools.
How politics in Minneapolis are putting law enforcement at risk
Minneapolis offers a warning for law enforcement leaders as political conflict undermines coordination and officer safety
Things I never travel without, from woman who's been to all 50 states
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Sports Companies to Watch in 2026’s IPO Boom
In 2026, Fanatics, New Era Cap and SeatGeek could go public
Chipotle is getting more serious about politics, forming a new PAC
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Liftoff IPO filing signals possible end to adtech market freeze
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ChatGPT is getting ads
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David Harbour underwent 'intense psychotherapy' for bipolar disorder: 'There is not a cure-all formula'
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David Harbour reveals he recently started 'intense psychotherapy'
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Looking for a new quantum stock? Honeywell plans an IPO of its Quantinuum business.
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The New Mercedes S-Class Has Stronger Engines
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Hawaii secures nearly $190M in federal funding for rural health care
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5 ground-breaking — and quirky — products from the 2026 CES
From a lollipop that lets you taste sound to a Tamagotchi style AI pet that physically grows, here are the coolest tech you could get your hands on.
5 ground-breaking — and quirky — products from the 2026 CES
From a lollipop that lets you taste sound to a Tamagotchi style AI pet that physically grows, here are the coolest tech you could get your hands on.
Entertainment leaders amp up discussions about AI, creators and innovative tech at CES 2026
LAS VEGAS – The world’s largest tech showcase does not come without theatrics. Innovations and gadgets like a lollipop that sings to you as you consume it, a laundry-folding robot and a “smart” LEGO b...
Entertainment leaders amp up discussions about AI, creators and innovative tech at CES 2026
LAS VEGAS (AP) — The world’s largest tech showcase does not come without theatrics. Innovations and gadgets like a lollipop that sings to you as you consume it, a laundry-folding robot and a “smart”…
Entertainment Leaders Amp up Discussions About AI, Creators and Innovative Tech at CES 2026
LAS VEGAS (AP) — The world’s largest tech showcase does not come without theatrics. Innovations and gadgets like a lollipop that sings to you as you consume it, a laundry-folding robot and a “smart” LEGO brick have stolen the spotlight so far at CES 2026. But underscoring this year’s programming is ...
IPOs: Serious Business With Some Showbiz
Many stock exchanges pull out the showbiz stops to attract IPOs to their venues, employing lasers, gongs, dancers, confetti and more. It's a good time, but it’s also serious business, as exchanges compete for a dwindling number of listings in recent years. Bloomberg Television Anchor Tom Mackenzie takes a look at some of the entertaining ways initial public offerings are celebrated. (Source: Bloomberg)
UAH women’s basketball makes history with wild overtime win against defending GSC champs
UAH (12-3, 7-0) will host Christian Brothers (3-8, 0-5) on Sunday. Tipoff is set for 2 p.m. at Spragins Hall in Huntsville.
Chinese tech stocks charged into 2026 with an AI chip IPO surge and more listings lined up
Chinese AI and semiconductor stocks have rallied since the breakout of the China-made DeepSeek-R1 AI model in January 2025.
Cancer Capitalism: How Drug Companies and Health Providers Profit
Leading to overcharges, treatments that don’t extend lives and failed implants.
How national politics rode along in the patrol car in 2025
From political violence and immigration enforcement to shifting criminal justice policy, 2025 forced local law enforcement to absorb the consequences of national decisions — regardless of ideology
Mini brains reveal clear brain signals of schizophrenia and bipolar disorder
Tiny lab-grown brains are offering an unprecedented look at how schizophrenia and bipolar disorder disrupt neural activity. Researchers found distinct electrical firing patterns that could identify these conditions with high accuracy. The discovery opens the door to more precise diagnoses and personalized drug testing. Instead of guessing medications, doctors may one day see what works before treating the patient.
New California law expands Newsom’s mental health court
A new law taking effect on Jan. 1, 2026 expands CARE Court, a mental health program launched by Gov. Gavin Newsom, to include people diagnosed with bipolar disorder.
Barstool Sports founder raises nearly $500K for family of Del. trooper killed in DMV shooting
Cpl. Matthew “Ty” Snook is credited with protecting civilians during the deadly attack; he leaves behind his wife and 1-year-old daughter
Woman Suffers AI Psychosis After Obsessively Generating AI Images of Herself
A woman working for a generative AI image startup says the tech led her into a manic bipolar episode, which triggered psychosis.
Bill from Rep. Deluzio targets 'ripoff' of costly sports stadiums hot dogs and beer
As President Donald Trump calls affordability concerns a “hoax” and Democrats look to highlight the issue in the upcoming midterm elections,...
Medtronic’s diabetes spin-off files for IPO
Make way for MiniMed! Medtronic's diabetes division has filed the necessary paperwork to go public. The company hopes to be traded on Nasdaq under the symbol MMED.
Medtronic’s Diabetes Management Business MiniMed Files for IPO
The Northridge, California-based company had a net loss of $21 million on revenue of $1.5 billion for the six months ended October 24, compared with a net loss of $23 million on revenue of $1.3 billion in the corresponding period a year earlier, according to its filing Friday with the US Securities and Exchange Commission. The filing positions the company to join a busy slate of possible debuts in the first months of 2026.
Medtronic announces filing of IPO registration statement for Diabetes business, MiniMed
Medtronic plc (NYSE: MDT), a global leader in healthcare technology, today announced that its Diabetes business, which as previously announced will operate under the name MiniMed, has filed a registration statement on Form S-1 with the U.S. Securities and Exchange Commission (SEC) for a proposed initial public offering (IPO) of newly issued common stock. The separation is expected to be completed through a series of capital markets transactions, with a preferred path of an IPO and subsequent spl
Trump to Summon Health-Insurance Firms to Ask for Premium Cuts
President Donald Trump said he would convene insurance companies in the coming weeks in a bid to pressure them to reduce costs for Americans who will see their premiums rise following the expiration of Obamacare subsidies at year’s end.
India’s Health-Tech Firm Practo Said to Seek Banks for 2026 IPO
Practo Technologies Pvt., which runs a digital health platform, is planning an initial public offering, according to people familiar with the matter, joining a wave of companies rushing to capitalize on India’s buoyant market for first-time share sales.
Finley: MSU's sports IPO may cost it control of teams
Selling shares in athletic program raises questions about who's in charge
Schmidt Gives Keynote Address for Political Trust Conference
Professor Vivien Ann Schmidt gave the opening keynote address, titled Political Trust and Legitimacy in the Age of Populism, for the Political Trust conference, organized by CEVIPOF at the French Political Science School at Sciences Po in Paris on December 5, 2025. This year’s conference, named Political Trust: A Challenge for Democracies, brought together researchers from…
AI's Political Persuasiveness Is Dangerously Good: Parmy Olson
Scientists found that the latest AI models are getting better at persuading people, but at the expense of the truth, using a debating tactic known as Gish galloping. Researchers tested 19 language models on nearly 80,000 participants and found that when chatbots were prompted to overwhelm users with information, their factual accuracy declined. Bloomberg Opinion columnist Parmy Olson discusses the impact of AI and the power of Persuasion on The Pulse. (Source: Bloomberg)
Kansas football's Lance Leipold reacts to Chris Klieman’s retirement
Earlier this month, Kansas State football coach Chris Klieman announced he was retiring. Here’s what Kansas coach Lance Leipold said about that.
Dental Stem Cells Show Promise Beyond Oral Health
Multipotent dental stem cells can give rise to various cell types and show potential for treating injuries, diabetes, and heart disease in early clinical trials.
Music City Madness: How sports build community across fanbases
For University alum Larry Gies, sports are all about a community coming together. Before tipoff for Illinois men’s basketball’s game against Tennessee at Bridgestone Arena on Dec. 6, Gies talked about what an off-campus event like this means. “I think it’s just all about community,” Gies said. “Life’s about community, life’s about interacting with people,...
SpaceX’s possible $1.5 trillion IPO could be big business for Texas
SpaceX, the Elon Musk-owned aerospace company, is planning to go public next year with a potential $1.5 trillion IPO, which would set a new record for a new public offering and have a huge impact on the Texas economy.
Musk reportedly plans record IPO for SpaceX. Here’s what that means
Elon Musk, already the world’s richest man, could soon be much richer. Bloomberg reports he’s planning one of the largest initial public offerings in history for SpaceX.
Reddit is testing verification badges
Verified users will actually be notable figures, not just people who paid for the checkmark.
Findings may move science closer to growing organs in other species
Failure of human pluripotent stem cells (PSCs) to survive when grown with the PSCs of distantly related species occurs because of an innate immune reaction in the nonhuman cells, a study led by UT Southwestern Medical Center researchers suggests.
14 CEOs reveal the pump-up playlist that powers their day
Mark Cuban, Jesse Itzler, and CEOs of companies including Olipop and Solidcore shared the songs that get them energized.
Tony Fadell, iPod co-creator, might want to be Apple’s next CEO: report
A new report offers an overview of possibilities for when Apple’s CEO Tim Cook steps down, including Tony Fadell returning.
Enemy Reaction 2025: Minnesota Vikings
The 12s were loud and proud at Lumen Field, while Vikings fans had little to cheer for once again.