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‘Coyote vs. Acme’ surges past expectations, snagging No. 2 at domestic box office after cancellation
‘Coyote vs. Acme dropped an anvil on the domestic box office this weekend, surpassing projections for a $15.4 million premiere that placed it just behind ‘Spider-Man: Brand New Day’ and just ahead of ‘The Odyssey.’
3.2K views · 13 reactions | Our media and politics reporter Ken...
Our media and politics reporter Ken Bensinger examines how political campaigns in the U.S. are increasingly paying social media influencers for support, though the ties are not always clearly...
Rabies outbreak at North Carolina mobile petting zoo triggers health warning
4 baby goats left dead after rabies outbreak, officials said
iPhone 18 Pro Pre-Orders May Start at an Unusual Time
Pre-orders of Apple's iPhone 18 Pro may not open until Saturday, September 12, a day later than the company's usual schedule, according to a new report. Apple is set to hold its annual iPhone event on Wednesday, September 9, where the iPhone 18 Pro models, its first-ever foldable iPhone, and the Apple Watch Series 12 and Ultra 4 are all expected to be announced.
Friday sports: Watertown’s new coach, new era
Shane Countryman is running the team this year.
Music Legend, 82, Makes Bombshell Career Announcement Amid Health Fears
Fans had been concerned about the seven-time Grammy winner.
Woman arrested in connection to Tillamook illegal massage business investigation
A woman was arrested at a Tillamook massage parlor on Thursday in connection to an illegal massage business investigation, according to police.
FDA just approved updated covid shots. Here’s what to know as cases rise.
Questions remain over formal federal recommendations for which Americans should get a vaccine, which could complicate availability of the shots in a handful of states.
Longtime local sports reporter to be added to Kinnick Media Wall of Fame
Steve Batterson will be inducted posthumously alongside Gary Dolphin, Mike Hlas and Steve Roe the weekend of Sept. 18 - 19.
Nominate a local business for a chance to win a Browns sponsorship
Deadline to submit a nomination is Dec. 31
Hot rods, custom cars and live entertainment set for QC Nationals weekend
The NSRA Quad Cities Street Rod Nationals return Aug. 28–29 to the Mississippi Valley Fairgrounds with two days of classic cars, custom builds, live entertainment, contests and family activities for automotive fans.
Essex mental health trust's leaders need to improve, says CQC
It issues its latest report on an NHS trust under scrutiny at an inquiry into mental health deaths.
Senator Markey had ‘iPad' moment. Will it help Moulton's age pitch?
Perhaps now more than ever, the nation’s aging political class is once under renewed scrutiny.
South Africa’s ‘manganese queen’ suffers fresh court setback in $530 million debt battle
South Africa’s “manganese queen” Daphne Mashile-Nkosi has suffered a court setback in Kalagadi Manganese’s $530 million dispute with state lender IDC
Jameson Parker Joins QC Entertainment As President Of Production
Jameson Parker has joined QC Entertainment ('Get Out,' 'BlacKkKlansman') as President of Production, Deadline can report exclusively.
Sword Health to acquire Headspace in all-cash deal
Virtual physical therapy platform Sword Health is planning to acquire digital mental health company Headspace in an all-cash deal, according to a regulatory filing from the latter. | The virtual physical therapy and mental health platforms are targeting a September close, per a regulatory filing. A price tag was not disclosed, but is being reported to land between $200 million and $300 million.
Class-action lawsuit claims UnityPoint Health shortchanged hourly workers
A potential class-action lawsuit filed on behalf of employees of UnityPoint Health alleges the hospital chain has violated wage-and-hour laws by rounding down workers’ actual hours.
Boston Scientific hit by cyberattack causing ‘disruptions’ to parts of its business
This year has seen a growing number of medtechs hit by cyberattacks, and now Boston Scientific has become the latest victim. In an SEC filing posted Aug. 26, the medtech giant said it had detected a “cybersecurity incident” the day before. The incident has affected certain parts of its information technology systems, something that “has resulted in a global disruption to the company’s operations.” The incident has hit not just its information systems but also its business applications, which “support aspects of the Company’s operations,” it said in the filing. This includes its ability to process and ship customer orders. Boston Scientific said it is working to restore the systems, but the timeline remains unknown. Related Baylor Genetics hit by cybersecurity attack targeting patient, staff information As the company investigates the incident, it remains unclear how significantly its business will be affected. “Accordingly, the Company has not yet determined whether the incident is reasonably likely to have a material impact.” The company’s shares were down 3.5% in premarket trading as the news broke. This adds another layer of pressure for the medtech, which last month revealed a new global restructuring program that starts this year and is slated to be completed by 2029. The company said at the time that it “does expect some headcount reductions to result from these restructuring activities,” but did not provide any numbers or specify areas where the cuts may be made. It added, however, that new jobs are also set to be “created in areas of growth.” It was also forced to cut its sales guidance in Q2, saying in late July that it now expects full-year 2026 organic revenue growth of 5% to 6%, down from its previous guidance of 6.5% to 8%. Boston Scientific is one of a growing number of life sciences companies, notably medtechs, that have been hit by cyberattacks this year. These include Abbott, iRhythm, Medtronic and Stryker, as well as Big Pharmas Amgen and Novo Nordisk.
Apple Maps Ads Are Here, and There's No Way to Turn Them Off
Ads in Apple Maps are live in the United States and Canada, which means iPhone and iPad users will see them when searching for locations and when viewing Suggested Places. Apple announced plans to bring ads to the Maps app in March, and said the feature would roll out starting in late summer. Apple confirmed to 9to5Mac that ads began showing up for users over the last few days, with ad placement to ramp up in the coming weeks.
Fullspan Health’s AI agent sees strong early traction with 1.1M views since June launch
Fullspan Health’s conversational artificial intelligence agent is gaining traction among users. | The conversational AI tool—dubbed Healthline AI—is sourced directly from the publisher’s medically reviewed properties.
iPhone 18 Pro and iPhone Ultra: When Will Apple Event Be Announced?
It is now late August, meaning that Apple's annual iPhone event is just around the corner. Below, we take a look at when the event might be held this year. This September, Apple is expected to unveil the iPhone 18 Pro, iPhone 18 Pro Max, and an all-new foldable iPhone that will reportedly be named the iPhone Ultra. The regular iPhone 18, a lower-end iPhone 18e, and the iPhone Air 2 are not expected to be announced until around March 2027, as part of a new launch strategy.
Hundreds gather in Tuscaloosa for statewide behavioral health conference
Organizers said more than 500 people attended the conference either in person or online.
Apple Preparing to Increase iPhone Prices
Apple is preparing to raise iPhone prices following similar moves from Samsung and Google, according to Bloomberg's Mark Gurman. Apple raised prices on almost every major product category two months ago, with affected Macs and iPads rising about 23% on average. In the latest edition of his "Power On" newsletter, Gurman said that the iPhone faces the same memory and chip supply chain issues affecting Apple's other products, so a price increase "remains inevitable".
Health systems warn patients of MyChart phishing scam
Scammers are masquerading as MyChart to trick patients into providing personal information. Epic says that the increase in phishing attempts are just cybercriminals taking advantage of the MyChart brand rather than a security concern.
Healthcare was built around specialties. Patients experience it as one journey.
Care coordination starts by designing healthcare around people, not disconnected systems.
Why environmental performance is becoming a business priority for solid waste
For solid waste operators, environmental performance has always been essential. What’s shifting now is its central place in core business strategy.
Kirkwood bond would pay for needed equipment and technology upgrades for health care students
Voters across 18 Iowa counties will decide this fall whether to approve an $88 million bond to upgrade Kirkwood Community College, including new equipment for nursing and EMT students.
Archaeologists unearth a medieval nobleman buried with his horse and dog in a rare wooden tomb in Russia
A rare example of a wooden chamber tomb reveals connections between medieval Norse and Old Russian burial styles.
Owner of rehabilitation business arrested after allegedly sexually abusing client
The owner of a rehabilitation business that helps people with sober living, was charged with two counts of sexual abuse, along with several drug possession charges.
Weekly Rundown: Expressable joins Amazon's health conditions program; Function launches data connector for AI platforms
Stay up to date on the latest in health tech, digital health and health AI news with this weekly brief. This is news from the week of Aug. 17 to 21. | Stay up to date on the latest in health tech, digital health and health AI news with this weekly brief.
Data center politics take over PA midterms
Candidates in at least 20 competitive legislative races are staking out data center positions, and PA Gov. Josh Shapiro has pivoted to a tougher stance.
Regeneron podcast turns science learnings into immersive experience
Regeneron is showing off its science in a whole new light with its “Science Illuminated” series, a unique vide | Regeneron's "Science Illuminated" podcast series transforms scientific topics into a calming, meditative-style video and audio experience.
Urban Roots Farm gives local students hands-on agriculture, business experience
A North Memphis school is allowing students to get their hands dirty to learn.
ChatGPT Can Now Control iMessage, Potentially Raising Apple Privacy Concerns
OpenAI rolled out support on Thursday for controlling Apple Inc.’s iMessage service via ChatGPT, a move with the potential to raise privacy concerns for the iPhone maker.
Cityblock acquires Homeward Health to move into rural healthcare, lands $116M funding round
Cityblock Health, a company primarily focused on providing care for urban Medicaid and dual-eligible members, is acquiring Homeward Health to expand deep into rural markets, the company announced T | Combined, the two companies will serve nearly 250,000 people and are positioned to reach the120 million people receiving government-funded healthcare in the U.S., Toyin Ajayi, Cityblock Health CEO and co-founder wrote in a blog post.
Elmhurst students’ summer of science
Children’s learning loss over the summer is an age-old concern for parents. To combat it, plenty enroll their youngsters in summer programs to keep the gears turning.That can be a
Q Street reopening delayed again to October, frustrating southwest Omaha business owners
Rainy weather is not what several southwest Omaha business owners want to see. It means another delay on a street construction project that has already slowed customer traffic.
Guggenheim’s beaten-down loan whipsaws as lenders digest call
Executives steered clear of details about the wide-ranging probe into Mark Walter’s business empire.
Cloudflare Workers Spectre Attack Leaks JWT From Co-Located Worker at 12 Bits/Second
Researchers leak a JWT from a co-located Cloudflare Worker via Spectre at up to 12 bits per second; Cloudflare says the attack is mitigated.
Review: In a deluge of free entertainment, Alternating Currents 2026 flowed into a loading dock, record store and the QC's coolest venues
The Quad Cities’ annual Alternating Currents Festival landed on a rainy weekend this year (Aug. 13-16), but the weather didn’t dampen the spirits gathering for over 200 events across Davenport, Bettendorf and Rock Island. The smiles outlasted the downpours as free music, art, comedy and film events carried on, albeit with few a cancellations, a […]
Action 9 helps consumer get tax refund after double health insurance enrollment
A woman discovered she owed thousands of dollars for two health insurance policies after switching to private coverage.
Is rock dead? Music awards show scraps major category
The 2026 nominees have ben announced.
Walter’s insurer to slash scrutinized loans by $6.5 billion
The move whittles down the more than $20 billion of loans that insurers controlled by Walter previously said should have been labeled as affiliated but weren’t.
Humans Love Having Pets. Seems Like Some Other Primates Do, Too.
We aren’t the only animals that like to take care of other species. A new study finds that the roots of keeping a pet may stretch deep into our primate past.
Akin, an Elite Global Law Firm
Akin energy & infrastructure partner Mitch Holzrichter has been named to Crain’s Chicago Business’ 2026 Notable Leaders in Accounting, Consulting & Law, which recognizes professionals whose work…
Happy Health secures $75M to expand AI-powered care in the home starting with sleep apnea
Digital health company Happy Health secured a $75 million series A funding round to continue building its artificial intelligence-powered platform for continuous home-based care. | The startup’s smart ring—dubbed Happy Ring—was first cleared by the FDA in 2024.
Democrats enter their thirst trap era
The left is leaning into candidates who look young, energetic and even desirable, with fresh faces often eclipsing the older guard.
Ohio firefighters responding to explosions and a fire at Toledo industrial recycling business
Explosions have rocked an Ohio industrial recycling business, sparking a large fire that drew emergency responders
Brown: There’s a Gen X-sized hole in our economy, politics and culture
"We followed a Baby Boom generation that was much larger, and therefore intractable from leadership roles. We even had the most lead exposure of any recent generation, which can’t be good," columnist Aaron Brown writes.
iPhone 18 Pro Max Rumored to Get Exclusive Camera Upgrade
Apple's upcoming iPhone 18 Pro models may be differentiated by a new camera feature that could be exclusive to the larger Pro Max model, if a Chinese leaker is to be believed. Since 2024, we've been hearing rumors about Apple's plans to introduce a variable aperture camera on the iPhone 18 Pro models – a first for any iPhone – but it was understood until now that the feature would come to both devices. Leaker Ice Universe claims that's not the case.
How Brookhaven National Laboratory’s CFO finances big science
Dr. Susan McKeon explains why the financial decisions behind some of the world's most ambitious scientific research requires a different type of CFO approach.
iPhone 18 Pro and iPhone Ultra: New Details Leak as Apple Event Nears
"iPhone Ultra" supply will be very limited when the foldable device is first released later this year, according to Fixed Focus Digital, a known leaker on the Chinese social media platform Weibo. The account also claimed that the iPhone 18 Pro's A20 Pro chip will be up to 18% faster and up to 30% more power efficient compared to the iPhone 17 Pro's A19 Pro chip.
Pennsylvania Highlights Housing Investments to Improve Health
Pennsylvania officials have committed $1 million in state funding to connect vulnerable Medicaid recipients with housing and health services. | State funding will bring housing support for Medicaid recipients with chronic health conditions.
AirPods Max 2 Discounted by $120 Across Amazon and Best Buy
Apple's AirPods Max 2 have hit $429.00 on Amazon this week, down from $549.00. This sale is available in two colors on Amazon, while Best Buy has all five models in stock at this low price. Note: MacRumors is an affiliate partner with some of these vendors. When you click a link and make a purchase, we may receive a small payment, which helps us keep the site running.
‘A game changer’: UHS closes $835M Talkspace acquisition
Bringing Talkspace on board should expand behavioral health services for UHS’ existing patients, while ushering more consumers through the health system’s doors, UHS CEO Marc Miller said.
Before Abrupt Ouster, Oregon State Hospital’s Chief Flagged Staffing Problems, Union Says
The Oregon Health Authority fired Sean Murphy from leadership at the vital, much scrutinized state-run psychiatric hospital, just four weeks into a tenure that began July 13.
Six months after $147 million US health deal, Burkina Faso faces fresh sanctions threat from Washington
Burkina Faso is facing fresh pressure from Washington over alleged human rights abuses, just six months after the US agreed to provide up to $147 million in health assistance to the West African country
Best Disney+ deals and bundles: Best streaming deals in August 2026
Catch the best from Marvel, Star Wars, and more with these Disney+ deals and bundles.
Serie A livestream: How to watch Serie A for free
Live stream select Serie A fixtures without spending anything.
Lisa Kudrow and Mira Sorvino reveal Romy and Michele’s new love interests in sequel
‘Romy and Michele’ stars Lisa Kudrow and Mira Sorvino reveal their character’s new love interests in the upcoming sequel.
Skanska small business outreach lead sees opportunity in DBE changes
After hitting hiring goals on a Los Angeles International Airport project, DBE compliance officer Teresa Maxwell outlined how the firm connects with contractors local to its projects.
Police respond to break-in at local business in Tucson
The Tucson Police Department responded to a break-in on Aug. 11.
WSDG Completes The Kempinski Grand Hotel’s Ultra-Modern Entertainment Venue At Billionaire St. Moritz
Billionaire St. Moritz, an ultra-modern event location directly connected to the historic Grand Hotel des Bains Kempinski, has opened as the ultimate dinner show and clubbing experience in St. | Acoustic and AV technology designers deliver sophisticated room-within-room construction for exclusive dinner show and clubbing experience.
Common Health Coalition secures $100M from OpenAI Foundation to boost hepatitis C cure rates
The OpenAI Foundation invested $100 million towards a new public health initiative with the Common Health Coalition aimed at helping states and local jurisdictions close discovery-to-delivery gaps, | Funding will support the deployment of AI-enabled tools to help identify patients who have fallen out of care, reduce administrative burden, strengthen care coordination and improve patient outcomes.
Abbott to pump up blood supply with $1M college sports prize amid US crisis
Abbott is again tapping into the competitive spirit of Big Ten universities to drive blood donations,
‘Heated Rivalry’ actor says he got ‘in trouble’ after seemingly leaking info about upcoming episodes
Dylan Walsh, who plays David Hollander on ‘Heated Rivalry,’ paused his Cameo account after a video where he talked about season 2 of the hit hockey romance went viral.
Sports fans never sleep: Ericsson says 5G is becoming central to game-day
Fans increasingly expect seamless digital experiences before, during and after sporting events, p | The World Cup may be over, but the race to improve fan experiences is not. Advanced 5G networks are increasingly shaping everything from stadium connectivity and concessions to media production and public safety.
Opinion: AI isn’t the business
AI will transform how businesses operate without replacing what makes them valuable.
Inside Iowa Politics: What Sen. Ernst wants to do before leaving office
Sen. Joni Ernst confirmed what she wants to accomplish before she leaves Congress.
Oil rises as doubts over US-Iran deal heighten supply concerns
Oil prices rose on Wednesday morning as doubts about a U.S.-Iran peace deal and attacks on two ships fuelled concerns about Middle East supply disruptions, even as industry data showed U.S. crude inventories expanded.
Small business optimism rebounds to highest level since Aug. 2025: NFIB
Small businesses last month scaled back both actual and planned price increases for the first time this year, the National Federation of Independent Business said.
iPhone 18 Pro Will Reportedly Start With 256GB of Storage
While the iPhone 17 Pro has double the base storage compared to the iPhone 16 Pro, there will apparently be no further increase this year. In a report this week estimating that the iPhone 18 Pro's bill of materials will be nearly 40% higher than the iPhone 17 Pro, Taiwanese research firm TrendForce said the iPhone 18 Pro will start with 256GB of storage, matching the iPhone 17 Pro's minimum capacity.
Terraria’s Calamity Mod devs reject xQc’s plan to save it after shutdown
The hugely popular mod recently announced it was shutting down, bringing development to an end after years of expanding the base game.
Quantum Computing Inc. Revenue Jumps as Acquisitions Expand Commercial Business
Quantum Computing Inc. reported $5.6 million in second-quarter revenue, largely driven by acquired businesses.
‘Family Affair’ actress Kathy Garver reflects on child costar Anissa Jones’ death at 18
‘Family Affair’ actress Kathy Garver reflects on child costar Anissa Jones’ tragic death at 18 and reveals a haunting plea the star’s mother made to her shortly before her daughter died.
Commentary: Forfeited properties can and should be redeveloped
Properties lost through tax sales have potential to be put back on the tax rolls and become an opportunity for community revitalization and more affordable housing.
AbCellera women’s health data top ‘most aggressive upside scenario,’ putting Astellas and Bayer on notice
AbCellera has reported phase 2 results “beyond even the most aggressive upside scenario” that its CEO dared to consider, boosting the biotech’s chances of challenging Astellas and Bayer for a women’s health market. The phase 2 clinical trial compared ABCL635, an antibody targeting NK3R, to placebo in patients with hot flashes caused by menopause. Investigators enrolled 92 postmenopausal women experiencing a mean of about 10 moderate or severe hot flashes per day. By Week 4, the number of moderate or severe hot flashes had fallen by a mean of 8.8 on ABCL635 and by 3.5 on placebo. That statistically significant, placebo-adjusted reduction of 5.3 hit the trial’s primary endpoint. The level of efficacy also cleared the bar set by existing drugs. While cross-trial comparisons can be misleading, AbCellera CEO Carl Hansen, Ph.D., had seen enough to start hyping the program. “We now view ABCL635 as a potential best-in-class non-hormonal therapy with strong differentiation against approved NK3R competitors across all important dimensions, including efficacy, safety, dosing and convenience,” Hansen said on a Monday morning conference call with investors to discuss the data. “We believe ABCL635 is now a highly de-risked program.” Last week, Hansen used AbCellera’s earnings call to set expectations for readout, with the CEO defining success as a clean safety profile and efficacy comparable to the two approved small molecules. The data vaulted over that bar. Astellas linked (PDF) one of the small molecules, Veozah, to placebo-adjusted reductions in hot flash frequency of 2.1 and 2.6 at Week 4 of its two phase 3 trials. Bayer reported (PDF) placebo-adjusted reductions of 3.04 and 3.29 at Week 4 of pivotal studies for its small molecule, Lynkuet. At 5.3, the placebo-adjusted reduction in AbCellera’s trial comfortably cleared the standard set by the incumbents. Veozah and Lynkuet came to market based on evidence of their ability to reduce the frequency and severity of hot flashes. AbCellera’s phase 2 study covered both endpoints, with the Canadian biotech reporting a mean reduction in severity of 1.4 points at Week 4 on ABCL635, compared to 0.3 points for placebo. Again, the placebo-adjusted result compares favorably to data on Veozah and Lynkuet. Analysts shared Hansen’s enthusiasm for the data. The phase 2 results “firmly validate ABCL635 as a potentially best-in-class treatment,” BMO Capital Markets analysts said in a note to investors Monday. ABCL635’s apparent efficacy edge “is likely attributable to the higher dosing/target engagement the asset is able to reach vs. the oral agents due to its wider therapeutic index,” the analysts added. The analysts, who model $2.3 billion in unadjusted peak sales for ABCL635, flagged the safety profile as another positive of the phase 2 readout. While Veozah carries a boxed warning for liver damage, nobody on ABCL635 in the phase 2 trial had elevated liver enzymes or bilirubin values. If replicated in phase 3, the lack of a liver signal could allow approval without the monitoring requirements imposed on Veozah. Investors appeared equally enthused, sending AbCellera's stock up 32% to $9.21 in premarket trading Monday from a Friday closing price of $6.93. Next, AbCellera will collect the Week 12 data and talk to its advisors about further development. The results open up “a wide variety of possibilities of how we might take this forward into phase 3 studies to truly maximize the value of the asset and make sure that ABCL635 is able to demonstrate its differentiation potential,” Sarah Noonberg, M.D., Ph.D., AbCellera’s chief medical officer, told investors.
Members of Congress seek to stabilize radiologist pay in Medicare program
A broad coalition of doc groups has endorsed the measure, including the AMA, American College of Radiology and the American Society for Radiation Oncology.
The next challenge for AI in healthcare isn’t adoption. It’s connection.
Healthcare organizations are moving beyond AI experimentation and focusing on operational value.
How hospital monopolies are driving up the cost of your health care
A federal disclosure rule is offering new insight on the effect of health care monopolies on pricing, following a wave of U.S. mergers.
Here are The Observer’s top 25 NC football recruits. Where will they play in college?
In all, 16 of the top 25 are headed out of state, including the state’s top player. How many are going to Duke, NC State or UNC?
New CSS Attacks Can Break Webmail Defenses to Steal Passwords and Tokens
Outlook CSS techniques can spoof Microsoft sign-in and capture passwords, while Gmail image-set() can trigger external requests from malicious email c
The 5 daughters of Africa’s richest men: Inside the corporate power and business of the Dangote and Rupert heiresses
Across Africa’s most influential billionaire dynasties, a new generation of women is stepping into major business roles
Palmetto Sports Daily: Panthers win preseason thriller, Gamecocks kick off fall camp
The crew recaps a thrilling win for the Panthers in Canton and dishes more on the start of fall camp for Gamecock football.
AHF Launches Health and Housing Newsletter
There is growing recognition that housing is more than a roof over someone’s head—it’s a critical driver of health and well-being. | The newsletter comes as the two sectors are working together for better resident, business, and community outcomes.
Amazon Researcher Claims Quantum Algorithm Could Challenge PQC Foundations
The Quantum Insider (TQI) is the leading online resource dedicated exclusively to Quantum Computing.
Federal Reserve’s Lisa Cook tells Anchorage business crowd she’s ‘firmly committed’ to bringing down inflation
High inflation for five years has contributed to negative views of the economy, even as it’s largely stable, Lisa Cook said.
Sanofi suspends chronic lung disease phase 2 study, tied to ‘strategic business reasons’
Sanofi halted a phase 2 trial testing a monoclonal antibody, SAR445399, in non-cystic fibrosis bronchiectasis, Fierce Biotech has learned. The trial, which began only back in April, was a randomized, double-blind, placebo-controlled study to measure the reduction in mucus plug score following treatment with SAR445399 compared with placebo in adults aged 18 to 80 years with NCFB, a chronic lung disease. The trial was officially reported as halted on July 29, the day before Sanofi’s second-quarter earnings call. The decision to pause the trial was made “as part of a company-wide portfolio review for strategic business reasons,” and not due to safety concerns, a Sanofi spokesperson told Fierce. The move to pause the NCFB trial comes during a trying time for Sanofi following a year filled with a series of trial fails. In February, the French pharma ousted CEO Paul Hudson and appointed Merck KGaA leader Belén Garijo, M.D., Ph.D., to steer the ship. Since then, Garijo has been doing a deep dive on correcting the company’s strewn R&D and clinical strategies. On July 24, Sanofi scrapped amlitelimab for atopic dermatitis, despite its lore as being a potential $5 billion blockbuster. During its second-quarter report, the company abandoned two more assets, balinatunfib and itepekimab, following failed trial results in psoriasis and chronic obstructive pulmonary disease, respectively. SAR445399, only first revealed by Sanofi in 2023, is an anti-interleukin-1 receptor 3 monoclonal antibody developed to block the interleukin 1, 33, and 36 cytokine pathways. These pathways can be important in chronic immune-related dermatologic diseases, such as atopic dermatitis and hidradenitis suppurativa, as well as respiratory conditions, such as NCFB. Related Sanofi’s new CEO ‘looking deeply’ at late-stage pipeline as clinical clearout continues NCFB affects roughly half a million people in the U.S., with a global incidence of greater than one million cases. In August 2025, Insmed received FDA approval for Brinsupri, a DPP1 inhibitor targeting neutrophil activation, for treatment of NCFB in adults and kids ages 12 and older. The British biotech Infex Therapeutics showed promising NCFB phase 2a data using their monoclonal antibody, INFEX702, which acts by disabling Pseudomonas aeruginosa, a bacteria known to be a major pathogen of NCFB. Sanofi is currently running a separate phase 2 study testing SAR445399 as a potential treatment for the inflammatory skin condition hidradenitis suppurativa.
Untold Sports Documentary Series Returns with Vince Young, Raygun, and Mr. T
Acclaimed docuseries highlights college football legend, viral Olympic breakdancer, and cultural icon.
Construction continues as WVSOM science building expansion takes shape
PRESS RELEASE LEWISBURG, W.Va. – Greenbrier County residents may notice that a building on the West Virginia School of Osteopathic Medicine’s (WVSOM)
Opinion | Trump’s NSF cuts would undercut gold standard science
Trump says he wants better science, but his NSF budget would weaken reform.
Small Business Owners Testify on U.S. Economic Growth
The Senate Small Business and Entrepreneurship Committee holds a hearing on tax policy, artificial intelligence, and other issues impacting small businesses.
Garfinkel steps away as Dolphins president. Sillman takes on larger role. Details
Dolphins announce changes in leadership. Here’s the team’s succession plan and more.
David Ellison says court fight over Warner Bros. is about his politics, CNN
The Paramount Skydance CEO defended his deal to buy Warner Bros. Discovery and said he’s voted for Democrats and Republicans and held liberal and conservative values.
Stakeholders Testify on Medicaid & Health Care Costs
Stakeholders testify on Medicaid, the cost of care, and program funding needs bedore the Senate Budget Committee.
Gov. Bill Lee
It was an honor to join business & community leaders with the Rotary Club of Nashville today to highlight our city & state’s bright future.
Amgen says patient health data, IP stolen in cybersecurity breach
Hackers recently accessed Amgen’s cloud environment, stealing sensitive patient health information and proprietary company data, the company disclosed in a securities filing on Friday. | Hackers recently accessed Amgen’s cloud environment, stealing sensitive patient health information and proprietary company data, the company disclosed in a securities filing on Friday.
Blanche rescinds 'anti-weaponization fund' for Trump allies after GOP senators threaten to block his AG bid
Acting Attorney General Todd Blanche has issued a formal order terminating President Donald Trump’s $1.8 billion “anti-weaponization fund” to compensate his political allies.