SCROLL NEWS / DISCOVERY

Search headlines

Find the stories shaping the conversation.

Search mode
Refine results
Active filters Keyword All time

Results for " sala " 554 found 🔀 AI-powered Shuffle

Trump repeats call for Congress to rein in college sports

President Donald Trump on Tuesday repeated his call for Congress to pass legislation that would rein in college sports at a time athletes are allowed to move freely from school to school and command salaries that put athletic departments in...

africa.espn.com logo
Apr 21 • 7:21 PM EDT • Sports • africa.espn.com
Trump repeats call for Congress to rein in college sports

President Donald Trump on Tuesday repeated his call for Congress to pass legislation that would rein in college sports at a time athletes are allowed to move freely from school to school and command salaries that put athletic departments in...

espn.com logo
Apr 21 • 7:21 PM EDT • Sports • espn.com
A former Missouri lawmaker wins back thousands of dollars seized after sexual misconduct allegations

A former Missouri lawmaker who was censured over sexual misconduct allegations has won a court case to recoup thousands of dollars seized from his salary as a penalty | Newsradio 1140 WRVA

audacy.com logo
Apr 21 • 3:30 PM EDT • Politics • audacy.com
Leading with heart: Juan Salazar’s mission to advance pediatric health care for all children

An internationally recognized pediatric infectious diseases specialist and investigator, Salazar brings decades of leadership and experience to Vanderbilt Health.

news.vumc.org logo
Apr 21 • 10:09 AM EDT • Health • news.vumc.org
Do Arsenal need 'different style' for forwards to flourish?

It is rare for a team to be challenging for the title without a forward in the conversation for team of the season, but it is difficult to argue against the fact that is where Arsenal are. Manchester City's Erling Haaland and Antoine Semenyo will undoubtedly be in contention for the end-of-the-season awards while past title-winners have boasted the likes of Mohamed Salah, Sergio Aguero and Didier Droga. Arsenal's available forward options of Viktor Gyokeres, Kai Havertz, Gabriel Martinelli, Noni Madueke, Eberechi Eze and Gabriel Jesus undoubtedly have their strengths - but it feels a stretch to call any of them ruthless match-winners.

sports.yahoo.com logo
Apr 20 • 3:25 AM EDT • Sports • sports.yahoo.com
Los Alamos Public Schools Students Compete At 2026 New Mexico State Science & Engineering Fair

Students from Barranca Mesa Elementary, Mountain Elementary, Los Alamos Middle School, and Los Alamos High School at the 2026 New Mexico State Science & Engineering Fair at New Mexico Tech. Pho…

losalamosreporter.com logo
Apr 20 • 12:21 AM EDT • Science • losalamosreporter.com
Deep dive
😐 Neutral (18%)
wow
100%
Salah writes history again with Merseyside derby opener 👑

Mohamed Salah has scored the first Merseyside derby goal at the Hill Dickinson Stadium with the opener in Sunday afternoon's Premier League clash. The Reds are on the hunt for Champions League qualifi...

sports.yahoo.com logo
Apr 19 • 9:47 AM EDT • Sports • sports.yahoo.com
Premier League: Salah starts for Liverpool against rivals Everton

Follow build-up to three games at 14:00 BST, including the first Merseyside derby at Hill Dickinson Stadium.

sports.yahoo.com logo
Apr 19 • 8:00 AM EDT • Sports • sports.yahoo.com
Scientists say this type of olive oil could boost brain power

Extra virgin olive oil might help protect your brain by working through your gut. A two-year study found that people who consumed it had better cognitive performance and more diverse gut bacteria than those using refined olive oil. Researchers even identified specific microbes linked to these benefits. The findings suggest that choosing high-quality olive oil could be a simple way to support brain health as you age.

sciencedaily.com logo
Apr 18 • 8:00 AM EDT • Science • sciencedaily.com
See how LSU’s coastal environmental science major produces successful graduates

The LSU Olinde Career Center’s outcomes data for last year’s undergraduate class revealed high starting salaries and an increased positive outcome rate for coastal environmental sciences. A positive outcome means a graduate has secured an opportunity such as employment or admission to graduate school within six months of graduating. CES graduates had a positive outcome...

lsureveille.com logo
Apr 15 • 6:00 AM EDT • Science • lsureveille.com
Industry Insight: See How Your Business Compares With Pay and Benefits for Key Roles

The Scoop’s annual salary survey offers benchmarking data to aid with recruiting and retaining ag retail employees.

thedailyscoop.com logo
Apr 14 • 1:04 PM EDT • Business • thedailyscoop.com
The Salary Penalty: Why Trump’s Tax Bill Hits a Banker Harder Than a Plumber

These days the biggest factor determining what high earners owe the government is how they make their money.

bloomberg.com logo
Apr 14 • 6:00 AM EDT • Business • bloomberg.com
Maria Elvira Salazar raises nearly $1M in three months as she gears up for re-election

The South Florida Republican is running for a fourth term in a battleground district.

floridapolitics.com logo
Apr 12 • 5:00 AM EDT • Politics • floridapolitics.com
RDC Hosts Free Business Booster Workshop And Intensive Networking Lunch April 14 At SALA

Visit the post for more.

losalamosreporter.com logo
Apr 11 • 4:19 PM EDT • Business • losalamosreporter.com
😐 Neutral (-1%)
wow
100%
Salah, Ngumoha ease Liverpool crisis with Fulham win

Liverpool's rising star and departing legend combined to ease the pressure on Arne Slot as goals from teenager Rio Ngumoha and Mohamed Salah beat Fulham 2-0, snapping the Reds' three-game losing streak on Saturday.Salah failed to get on the pitch at all during Liverpool's chastening 2-0 Champions League defeat by Paris Saint-Germain in midweek.

sports.yahoo.com logo
Apr 11 • 2:34 PM EDT • Sports • sports.yahoo.com
Deep dive
😐 Neutral (7%)
love
50%
wow
50%
Not All “Plant-Based” Diets Are Equal for Brain Health

A large study suggests healthier plant-based diets may be linked to lower dementia risk, while processed plant foods may not. The findings show association, not proof.

psychologytoday.com logo
Apr 11 • 8:00 AM EDT • Health • psychologytoday.com
Yankees news: Volpe slated to start upon return

Volpe expected to retake starting gig once healthy; flaws emerge as Yanks nosedive from hot start; Average salary in MLB rises; Mike Ford retires, takes role in Rays’ front office.

sports.yahoo.com logo
Apr 11 • 5:00 AM EDT • Sports • sports.yahoo.com
Record ODA Cuts: Top Donors Slash Aid As Global Health Risks Grow

Preliminary data from the OECD reveals historic ODA cuts, setting international aid back a decade. Civil society groups warn that the reductions will devastate funding for global health, education and social protection.

healthpolicy-watch.news logo
Apr 10 • 11:49 AM EDT • Health • healthpolicy-watch.news
SALARY GUIDE: Purdue’s top paid sports faculty

Here are the top five paid sports faculty members of 2025.

purdueexponent.org logo
Apr 10 • 8:00 AM EDT • Sports • purdueexponent.org
Off the Grid maker and Game Informer owner Gunzilla Games accused of missing staff salary payments

Current and former staff question the company's stability, alleging months of payroll problems

gamesindustry.biz logo
Apr 9 • 11:33 AM EDT • Technology • gamesindustry.biz
New York Giants’ star defender Dexter Lawrence salary demands revealed

The NFL is not only preparing for the 2026 NFL Draft—it has already begun voluntary workouts. Teams are now seeing players report for workouts, recovery plans, and general wellness checks. One notable name is absent from the New York Giants’…

sports.yahoo.com logo
Apr 7 • 6:41 PM EDT • Sports • sports.yahoo.com
Deep dive
😐 Neutral (9%)
wow
100%
Losing Dexter Lawrence Would Make the Giants’ Defense Collapse

After years of contract issues, New York Giants superstar defensive tackle Dexter Lawrence II has requested a trade. Lawrence’s disgruntledness doesn’t come as a surprise. Despite his All-Pro production, he ranks just 12th among NFL interior defensive linemen in terms of salary. So, with Lawrence’s established, elite production at 28 years old, the Giants shouldn’t hesitate […] The post Losing Dexter Lawrence Would Make the Giants’ Defense Collapse appeared first on The Lead.

sports.yahoo.com logo
Apr 7 • 3:58 PM EDT • Sports • sports.yahoo.com
‘This is what consolidation looks like’: Eliott Rodriguez reports $312K raised in 21 days for CD 27

The longtime Miami anchor is posting strong early numbers as Democrats jockey to challenge María Elvira Salazar.

floridapolitics.com logo
Apr 7 • 4:00 AM EDT • Politics • floridapolitics.com
ACPS students shine at State Science and Engineering Fair

Multiple students earn recognition at three-day event.

mainstreetdailynews.com logo
Apr 6 • 3:36 PM EDT • Science • mainstreetdailynews.com
Deep dive
😐 Neutral (21%)
love
55%
wow
45%
Meta salaries revealed: How much engineers, researchers made in 2025

See how much Meta paid in 2025, with software engineers earning as much as $450,000. Salary data shows pay ranges across over 5,000 roles.

businessinsider.com logo
Apr 6 • 5:00 AM EDT • Business • businessinsider.com
Prescott, Messi, Ohtani and more: How the world’s biggest sports stars get paid

From deferring salaries to taking ownership equity, we explore all the different ways the biggest names in sport get paid

nytimes.com logo
Apr 6 • 12:12 AM EDT • Sports • nytimes.com
😐 Neutral (13%)
wow
100%
ACPS student takes first place award at state science fair; seven others also recognized

Howard Bishop Middle School 8th-grader Aradhya Kasala won a first-place award at the State Science and Engineering Fair of Florida

alachuachronicle.com logo
Apr 5 • 5:40 PM EDT • Science • alachuachronicle.com
Key Leader at OHSU is Out After Brief Tenure

Tarek Salaway is no longer the health system’s CEO.

wweek.com logo
Apr 3 • 1:21 PM EDT • Health • wweek.com
💸 Goalkeeper joins the attack! La Liga's top earners

L'Équipe recently published numerous player salaries from Europe's top leagues. Of course, La Liga was included too. Here’s how much the top 5 in Spain earn per month (gross).5. Jude Bellingham (Re...

sports.yahoo.com logo
Apr 3 • 1:41 AM EDT • Sports • sports.yahoo.com
😐 Neutral (21%)
Gerrard reveals private message he sent to Salah after fallout

It’s not always what happens on the pitch that defines a Liverpool career, and now Steven Gerrard has revealed the advice he gave Mo Salah during one of the most difficult moments of his time at the...

sports.yahoo.com logo
Apr 2 • 5:25 AM EDT • Sports • sports.yahoo.com
Sports paper reveals figures! These are the Bundesliga top earners

French sports newspaper L'Équipe today estimated the gross salaries of the highest-paid Bundesliga players and coaches. Who do you think makes the most money per month? Coaches2. Kasper Hjulmand (Le...

sports.yahoo.com logo
Apr 2 • 4:42 AM EDT • Sports • sports.yahoo.com
Slot issues major Salah update ahead of Man City clash

It’s not often we get a clear injury picture heading into a huge game, but Arne Slot has now given us exactly that ahead of Manchester City, and there’s a mix of relief and concern across the squa...

sports.yahoo.com logo
Apr 2 • 2:40 AM EDT • Sports • sports.yahoo.com
Serie A winger linked with Liverpool as Salah replacement

Juventus Transfer Plans: Premier League Pressure Mounts as Champions League Stakes RiseChampions League Race Shapes Juventus FutureJuventus stand at a familiar crossroads, one shaped as much by financ...

sports.yahoo.com logo
Apr 1 • 2:50 AM EDT • Sports • sports.yahoo.com
Deep dive
😐 Neutral (12%)
wow
69%
ahah
31%
Night With A Nerd Is Back April 16 At Bradbury Science Museum

LANL NEWS RELEASE The Universe is bursting with activity with hundreds of cosmic explosions occurring every second. These explosions provide astronomers a window into the universe, studying everyth…

losalamosreporter.com logo
Mar 31 • 7:01 PM EDT • Science • losalamosreporter.com
😐 Neutral (4%)
wow
71%
ahah
29%
Forget free lunch and nap pods: AI startups are luring workers with soaring salaries—some recent computer science grads are making over $300,000

As Gen Z frets over the future of work thanks to AI, tech startups are dishing out sky-high six-figure salaries to secure top talent.

fortune.com logo
Mar 31 • 12:12 PM EDT • Science • fortune.com
2026 Best Business Schools | Salary, Bonus & Total Compensation Data For 2025 Business Graduates

After two years of sizeable jumps in compensation for business graduates, salaries, bonus, and total pay seems to be leveling off.

poetsandquantsforundergrads.com logo
Mar 30 • 3:21 PM EDT • Business • poetsandquantsforundergrads.com
Maria Elvira Salazar part of successful petition forcing House vote on TPS for Haitians

She will spearhead a similar effort with Darren Soto to grant Venezuelans the same treatment.

floridapolitics.com logo
Mar 30 • 4:45 AM EDT • Politics • floridapolitics.com
Report: Liverpool considering move to sign Serie A forward

Liverpool Transfer Latest: Francisco Conceição Emerges as Salah Contingency OptionLiverpool’s recruitment drive ahead of a crucial summer window continues to gather pace, with fresh developments p...

sports.yahoo.com logo
Mar 29 • 12:55 PM EDT • Sports • sports.yahoo.com
Biscan delivers huge claim after Liverpool Legends clash

There’s a growing sense across the football world that we’re witnessing the end of a truly historic Liverpool chapter, and Igor Biscan has now added his voice to the tributes surrounding Mo Salah....

sports.yahoo.com logo
Mar 29 • 11:35 AM EDT • Sports • sports.yahoo.com
Journalist rules out Mohamed Salah move after Liverpool exit

Mo Salah Exit Clarified as Inter Miami Stance EmergesUncertainty has long followed Mohamed Salah, yet clarity is beginning to form around his next move. Liverpool’s modern icon is now expected to de...

sports.yahoo.com logo
Mar 29 • 3:55 AM EDT • Sports • sports.yahoo.com
Former Liverpool star praises departing Mo Salah

Mohamed Salah Influence Shapes Liverpool Under Arne SlotAt Liverpool, individual brilliance often defines eras, and few have left a mark quite like Mohamed Salah. Speaking candidly, Dirk Kuyt reflecte...

sports.yahoo.com logo
Mar 29 • 2:55 AM EDT • Sports • sports.yahoo.com
Jarrod Bowen replacing Mo Salah is classic Liverpool

Jarrod Bowen to replace Mo Salah at Liverpool? It's a classic move from the Reds - and FSG.Mo Salah will leave Liverpool at the end of the season, bringing an end to nine wonderful years at Anfield. H...

sports.yahoo.com logo
Mar 28 • 5:35 AM EDT • Sports • sports.yahoo.com
Lewis Steele reveals Liverpool’s top target to replace Mohamed Salah

Liverpool Transfer News: Yan Diomande Heavily LinkedIn the latest Media Matters episode from Anfield Index, Dave Davis and Lewis Steele explored Liverpool’s forward planning, with Yan Diomande among...

sports.yahoo.com logo
Mar 28 • 3:55 AM EDT • Sports • sports.yahoo.com
Deep dive
😐 Neutral (10%)
ahah
50%
wow
50%
Carolina Complete Health and Centene Foundation Announce Investment and Groundbreaking of Major Affordable Housing Initiative in Northeast Winston-Salem with McCormack Baron Salazar

[auto]

investors.centene.com logo
Mar 27 • 8:00 AM EDT • Health • investors.centene.com
Democratic lawmakers highlight pay gap; business group raises concerns on wage transparency bill

Democratic lawmakers marked Equal Pay Day on Thursday by highlighting persistent wage disparities in Connecticut while backing legislation that would require employers to disclose salary ranges and benefits in job postings.

hartfordbusiness.com logo
Mar 26 • 11:54 AM EDT • Business • hartfordbusiness.com
BBC Sport weekly quiz: How many Premier League Golden Boots has Mohamed Salah won?

How much attention have you paid to what's happened in the world of sport over the past seven days?

bbc.com logo
Mar 26 • 3:51 AM EDT • Sports • bbc.com
Mohamed Salah: Who is the Premier League's greatest forward?

As Mohamed Salah announces he will leave Liverpool this summer, BBC Sport asks you to rank the best forwards in Premier League history.

bbc.com logo
Mar 25 • 2:30 AM EDT • Sports • bbc.com
Epstein accountant, lawyer explain finances in Congress testimony

Jeffrey Epstein's longtime lawyer Darren Indyke and accountant Richard Kahn manage Epstein's $630 million estate without salaries.

businessinsider.com logo
Mar 25 • 1:47 AM EDT • Business • businessinsider.com
Mohamed Salah's Remarkable Career At Liverpool, Broken Down In Numbers

A by-the-numbers look at Mohamed Salah's time at Liverpool after he announced he will be leaving the club at the end of this season.

foxsports.com logo
Mar 24 • 7:05 PM EDT • Sports • foxsports.com
DCCC reaches voters at the pump in 4 Florida congressional districts

The campaign will reach people in districts represented by Laurel Lee, Anna Paulina Luna, Cory Mills and Maria Elvira Salazar.

floridapolitics.com logo
Mar 24 • 1:58 PM EDT • Politics • floridapolitics.com
Broncos restructure Jaylen Waddle's contract for salary cap purposes

The Broncos converted Jaylen Waddle's option bonus into a signing bonus for salary cap purposes, according to KPRC-TV.

sports.yahoo.com logo
Mar 24 • 9:30 AM EDT • Sports • sports.yahoo.com
Salamander Migration Has New Citizen Science Component

Each spring, blue-spotted salamanders emerge from their underground burrows at Presque Isle Park in Marquette and venture across the road to lay their eggs. Northern Michigan University students have been involved in conservation, data collection and public education efforts for this annual event, but this year, the general public is invited to play a more active role in salamander migration research. Northern Michigan University Biology Department Head Jill Leonard encourages community members to participate in the Marquette Citizen Science Project.

news.nmu.edu logo
Mar 24 • 8:00 AM EDT • Science • news.nmu.edu
H-1B Health Care Workforce Bill Introduced

On March 17, Congressman Mike Lawler (NY-17) introduced the H–1Bs for Physicians and the Healthcare Workforce Act , bipartisan legislation with Reps. Sanford D. Bishop, Jr. (GA-02), Maria Elvira Salazar (FL-27), and Yvette Clarke (NY-09). This legisla...

ahcancal.org logo
Mar 24 • 8:00 AM EDT • Health • ahcancal.org
Arbitration case could bring change to NCAA's 'messy middle'

Why Nebraska's recent challenge could have wide-ranging salary cap implications.

espn.com logo
Mar 24 • 7:50 AM EDT • Sports • espn.com
Employees are taking pay cuts in huge numbers

After getting laid off, many professionals are being forced to take jobs with much lower salaries than what they were earning before.

businessinsider.com logo
Mar 24 • 4:13 AM EDT • Business • businessinsider.com
'Players' of an MMORPG for AI Agents Spontaneously Generated Their Own Religion

SpaceMolt is a new destination for vaguely portentous word salad.

gizmodo.com logo
Mar 23 • 4:35 PM EDT • Technology • gizmodo.com
Your Thymus and Your Healthspan

Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.

erictopol.substack.com logo
Mar 22 • 2:18 PM EDT • Health • erictopol.substack.com
Elon Musk offers to pay TSA workers' salaries amid DHS budget standoff

Elon Musk has offered to cover the salaries of TSA personnel during the ongoing funding impasse disrupting airports nationwide.

foxbusiness.com logo
Mar 21 • 7:07 AM EDT • Business • foxbusiness.com
Salary cap: OL Elgton Jenkins’ contract with the Cleveland Browns

Looking at the details of Browns OL Elgton Jenkins’ contract, option bonuses, and incentives.

sports.yahoo.com logo
Mar 20 • 8:36 PM EDT • Sports • sports.yahoo.com
☹️ Negative (-10%)
ahah
50%
wow
50%
Music Industry Jobs: The Core Entertainment, Republic Records, CAA

Music industry hires and promotions this week include job appointments at The Core Entertainment, MCA, Republic Records, CAA and AudioSalad.

billboard.com logo
Mar 20 • 12:39 PM EDT • Entertainment • billboard.com
He's one reason why aid cuts weren't as dire for the HIV population as predicted

Harerimana Ismail of Uganda is a community health worker who checks on kids with HIV. He lost his salary after the Trump administration's aid cuts but he keeps doing his job.

npr.org logo
Mar 20 • 8:10 AM EDT • Health • npr.org
High-Signal Publisher
Pittsburgh Steelers salary cap update after free agency

The Pittsburgh Steelers were active in the early portion of free agency, with general manager Omar Khan making waves with a big-time trade for wide receiver Michael Pittman Jr. and several free agency additions.

sports.yahoo.com logo
Mar 20 • 7:46 AM EDT • Sports • sports.yahoo.com
WNBA CBA expected to raise pay for other women's sports leagues

While salary increases were a win, observers suggest revenue sharing in the new WNBA collective bargaining agreement will be transformative.

latimes.com logo
Mar 20 • 12:43 AM EDT • Sports • latimes.com
Mathews Local School board freezes coach salaries, no sports cuts

Superintendent Russell McQuaide decided tonight that the programs can stay, but warned that diminishing funding will force them to make tough decisions in the future.

wfmj.com logo
Mar 19 • 6:38 AM EDT • Sports • wfmj.com
Malcolm Rodriguez Contract Details With Detroit Lions Emerge

The Detroit Lions have re-signed linebacker Malcolm Rodriguez. Here’s a full breakdown of his contract, salary, and cap impact.

sports.yahoo.com logo
Mar 18 • 10:17 AM EDT • Sports • sports.yahoo.com
Nvidia's Jensen Huang pitches tokens as recruitment strategy

Jensen Huang said engineers will soon be asking "how many tokens comes along with my job?" and is willing to pay them tokens worth half their salary.

businessinsider.com logo
Mar 17 • 12:02 AM EDT • Business • businessinsider.com
How 49ers are gaining a salary cap advantage

49ers are buying injury insurance on larger contracts to recover cap space to great effect

sports.yahoo.com logo
Mar 14 • 2:48 PM EDT • Sports • sports.yahoo.com
Deep dive
😐 Neutral (11%)
wow
64%
ahah
36%
The future of college sports is up for debate among the country's most powerful leaders. What's at stake?

From the introduction of federal legislation to salary caps and collective bargaining, the future is as murky as ever

cbssports.com logo
Mar 12 • 11:10 AM EDT • Sports • cbssports.com
WNBA CBA live update: Negotiations yield salary cap movement, no deal yet

The WNBA and its player union held another marathon meeting on Wednesday to talk through CBA obstacles. Here's what we know.

usatoday.com logo
Mar 12 • 10:12 AM EDT • Sports • usatoday.com
NFL salary cap tracker: How much cap space does each team have as legal tampering period hits Day 2?
sports.yahoo.com logo
Mar 10 • 2:56 PM EDT • Sports • sports.yahoo.com
Want stainless cookware, Italian food? Try these new NJ businesses

Dante's in Clifton serves Italian fare. Laon Table in Englewood sells Saladmaster stainless steel. Valley-Mount Sinai Children's Health is in Wayne.

northjersey.com logo
Mar 9 • 4:22 AM EDT • Business • northjersey.com
😐 Neutral (16%)
wow
57%
love
43%
Rep. Salazar says Trump is ‘sending a message to the political elite’ at Florida summit

Rep. Maria Elvira Salazar, R-Fla., discusses President Donald Trump’s remarks at the ‘Shield of the Americas’ summit in Florida and his administration’s efforts to make a deal with Cuba.

foxnews.com logo
Mar 7 • 1:56 PM EST • Politics • foxnews.com
😐 Neutral (4%)
wow
50%
ahah
25%
sad
25%
2026 NFL free agency mock draft: Kyler Murray to Jets, Mike Evans to 49ers, plus 30 more projected moves

Teams with the most salary cap space get the first "picks" in this free agency mock draft.

cbssports.com logo
Mar 7 • 9:37 AM EST • Sports • cbssports.com
2 Cardinals might return on lower salaries

Instead of an outright release, two potential cap casualties perhaps will take a paycut to remain in Arizona.

sports.yahoo.com logo
Mar 7 • 1:37 AM EST • Sports • sports.yahoo.com
😐 Neutral (12%)
wow
75%
ahah
25%
NFL salary cap tracker: How much cap space does each team have going into free agency?
sports.yahoo.com logo
Mar 6 • 12:48 PM EST • Sports • sports.yahoo.com
Now Hiring: Summer Jobs Available for Youth Sports Positions

Oyster Bay Town Supervisor Joseph Saladino announced that there are still openings for summer employment in the Town of Oyster Bay. Positions are available for the 2026 Youth Tennis and Basketball Programs. Those interested must be 16 years of age or older to apply. “These great summer jobs are ideal for community teens ages 16…

oysterbaytown.com logo
Mar 6 • 10:31 AM EST • Sports • oysterbaytown.com
Indianapolis Colts' Salary Cap Situation After Daniel Jones Tag
sports.yahoo.com logo
Mar 4 • 11:15 AM EST • Sports • sports.yahoo.com
Gaslight, Gatekeep, Girlboss: Pay and Leadership Gaps for Women in Public Health

Women in government public health face a persistent leadership and salary gap. Here's what the data shows — and what the field must do to close it.

debeaumont.org logo
Mar 4 • 9:16 AM EST • Health • debeaumont.org
Iraq, caught in the middle, braces for Iran war impact

Iraq is the only country in the Middle East to be targeted by both sides in the current conflict. There, the war could impact everything from the next government to intercommunal violence and civil servants' salaries.

dw.com logo
Mar 4 • 1:43 AM EST • Politics • dw.com
Deep dive
😐 Neutral (7%)
wow
43%
angry
34%
ahah
23%
Bizarro salamander ancestor was an evolutionary oddball

Paleontologists say 'Tanyka amnicola' had a jawbone that's a real head-scratcher.

popsci.com logo
Mar 3 • 7:05 PM EST • Science • popsci.com
#dubai #expatexperience #dubailife #expat #expatcommunity

The thought of leaving Dubai fills Kiran Ali with dread. Ali, a Washington, DC, import, moved to Dubai in March 2024. Speaking to Business Insider on Tuesday, she said she'll only leave Dubai if it becomes dangerous for her two young kids. "Dubai is the most fulfilled and happy I have been in my adult life," she said. "I have an incredible career, a purpose in community organizing, and great work life balance." For more than two decades, Dubai has marketed itself as a safe haven for expats with zero income tax, high salaries, and a luxury lifestyle. But the US and Israel's strikes on Iran over the weekend have thrown the Middle East into turmoil and raised questions about Dubai's future as a business, tourism, and expat hub. Read more about how expats on the ground aren't giving up on their expat dream so easily on Business Insider: https://lnkd.in/eM_ARYRU (Credit: Getty Images) #dubai #expatexperience #dubailife #expat #expatcommunity

linkedin.com logo
Mar 3 • 6:30 PM EST • Business • linkedin.com
😐 Neutral (28%)
wow
56%
ahah
22%
love
22%
Vikings to release RB Aaron Jones, DT Javon Hargrave at start of league year barring trade, per report

Minnesota would save 18.65 million against the salary cap by releasing both players.

cbssports.com logo
Mar 1 • 12:18 PM EST • Sports • cbssports.com
Deep dive
😐 Neutral (4%)
wow
80%
ahah
20%
Nakobe Dean's potential exit could evolve into a nightmare scenario

Nakobe Dean's time with the Eagles may be coming to an end due to salary cap issues. He could join the rival Dallas Cowboys.

sports.yahoo.com logo
Feb 28 • 12:25 PM EST • Sports • sports.yahoo.com
😐 Neutral (5%)
love
42%
ahah
33%
wow
25%
The 2026 NFL salary cap has been finalized

The salary cap has gone up another 22 million leaving the Bengals with plenty of cap room to sign defensive free agents.

sports.yahoo.com logo
Feb 27 • 8:09 PM EST • Sports • sports.yahoo.com
😐 Neutral (23%)
ahah
36%
love
36%
wow
28%
Slot on team fitness, Salah's drought and Ngumoha's improvement

Liverpool boss Arne Slot has been speaking to the media before Saturday's Premier League game against West Ham at Anfield (kick-off 15:00 GMT). Jeremie Frimpong has trained "a few times this week" so is available to face West Ham. Florian Wirtz remains sidelined with an injury which he described as "a disappointment for him and for us".

sports.yahoo.com logo
Feb 27 • 4:30 AM EST • Sports • sports.yahoo.com
😐 Neutral (12%)
ahah
55%
wow
45%
Despite the constant ‘job apocalypse’ warnings, computer science graduates are actually on track to earn $81,000 right out of college

New data suggests that fears about the demise of computer science majors may be overblown—with demand outpacing MBAs and starting salaries growing year-over-year.

fortune.com logo
Feb 26 • 12:15 PM EST • Science • fortune.com
Busting Through the Hype and Politics of Forest Thinning

Forest managers conduct hundreds of thousands of acres of forest “thinning” projects annually in the U.S., Canada, Australia, and elsewhere, resulting in substantial ecological and financial costs.

therevelator.org logo
Feb 25 • 11:00 AM EST • Politics • therevelator.org
Deep dive
😐 Neutral (8%)
wow
60%
ahah
40%
4 Arizona Cardinals getting big salary increases in 2026

Michael Wilson and three other Cardinals players have earned the proven performance salary escalator for 2026.

sports.yahoo.com logo
Feb 25 • 12:56 AM EST • Sports • sports.yahoo.com
Trimming the Vikings’ Salary Cap

The Minnesota Vikings are about $42 million over the estimated $303.5 million NFL salary cap for 2026 (the projected range is between $301.2 million and $305.7 million) and must get salary cap compliant by 4pm ET on March 11th. Beyond trimming $42 million in cap space (the Vikings currently are the most over the salary […]

sports.yahoo.com logo
Feb 24 • 7:50 PM EST • Sports • sports.yahoo.com
Scientists Discovered the Ancient, Unassuming Creature That Invented Salads

The 300 million-year-old Tyrannoroter heberti had an extra set of conical-shaped teeth, indicating it likely ate plants. It’s one of the earliest species to do so.

popularmechanics.com logo
Feb 20 • 8:30 AM EST • Science • popularmechanics.com
Trump Calls Himself a ‘Schmuck’ for Donating His Presidential Salary

President Trump complained that he gets “no credit” for the donations, though his family has done more to monetize the presidency than anyone who has ever occupied the White House.

nytimes.com logo
Feb 19 • 6:54 PM EST • Politics • nytimes.com
With federal dollars secured, Salango details next steps for Capital Sports Center project

Sen. Shelley Moore Capito announced $7 million in congressionally directed spending on Wednesday.

wvmetronews.com logo
Feb 19 • 11:29 AM EST • Sports • wvmetronews.com
😐 Neutral (8%)
ahah
53%
love
27%
wow
20%
Broncos can create massive salary cap space with simple restructures

The Broncos could utilize simple restructures to create massive salary cap space this spring.

sports.yahoo.com logo
Feb 19 • 9:00 AM EST • Sports • sports.yahoo.com
Eagles' salary cap breakdown: Which moves could free up millions?

Philadelphia has $18,152,388 in cap space and not many moves they can make to free up millions in relief

sports.yahoo.com logo
Feb 18 • 12:46 PM EST • Sports • sports.yahoo.com
Deep dive
😐 Neutral (8%)
wow
67%
love
33%
Vikings’ Top Cut Candidate Is Coming into Focus

Sitting $40 million over the salary cap in mid-February, the Minnesota Vikings are virtually guaranteed to release a handful of […]

vikingsterritory.com logo
Feb 17 • 2:03 PM EST • Sports • vikingsterritory.com
Always on, always judged: How Gen Z is reshaping retail

Many in Generation Z can justify shelling out $550 for a Coach purse but not dropping $15 for a Sweetgreen salad. The former is an investment that can look cute

unionleader.com logo
Feb 17 • 8:45 AM EST • Business • unionleader.com
Nike salaries: How much software engineers, designers, others get paid

Data shows how much Nike pays for engineers, designers, and other tech jobs, with salaries up to $425,000, as CEO Elliott Hill mounts a comeback.

businessinsider.com logo
Feb 15 • 5:41 AM EST • Business • businessinsider.com
Sarah Ferguson's massive salary for Epstein-backed business revealed

_New details reveal additional links betweenSarah Ferguson and Jeffrey Epstein. Keep reading to find out the details.

wonderwall.com logo
Feb 13 • 7:07 PM EST • Business • wonderwall.com
Deep dive
😐 Neutral (6%)
ahah
47%
wow
29%
love
24%
San Francisco Teachers Win Fully Funded Health Care, Wage Increases After 4-Day Strike

San Francisco’s first teachers strike in nearly 50 years concluded early Friday with a tentative agreement addressing the union’s concerns over health care, salaries and other key issues.

kqed.org logo
Feb 13 • 7:05 PM EST • Health • kqed.org
😐 Neutral (17%)
love
67%
angry
33%
Low-fat or low-carb — which is better for heart health? The answer may surprise you

New research shows that whole grains and plant-based foods, what researchers call a “quality” diet, are key to lowering the risk of coronary heart disease.

nbcnews.com logo
Feb 11 • 3:25 PM EST • Health • nbcnews.com
Deep dive High-Signal Publisher
😐 Neutral (12%)
wow
70%
ahah
30%