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Scholar Athlete of the Week: Andra Stokes, Stevens High School
KSAT 12 Sports and CHRISTUS Children’s shine a spotlight on a local senior student athlete
Locally-based behavioral health group to open first Louisville office
The location will provide individual, couples and family therapy.
French Local Elections Are Yardstick for Far Right. Initial Results Are Mixed.
France’s municipal elections ended on Sunday evening. Full results were not expected for hours, but the first projections suggested the far right may not have made major gains.
City of Paducah Finance Department to host informational workshop on Business License Renewals
In case you missed it, the City of Paducah Finance Department will host an informational workshop on Business License Renewals for local business owners at the McCracken County Library tomorrow,
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Fear of immigration enforcement in NC keeps immigrants home, hurting Latino-owned businesses
Immigration crackdown impact on local Latino-owned businesses
Latino business owners told WRAL News that fear and uncertainty following a nationwide crackdown in immigration enforcement are keeping some families out of public spaces, leaving small businesses struggling to survive. This story was written by Oriana Torre, a senior graduating journalism student at the University of Florida, participating in the CBC-UNC News Media Multiplatform Fellowship.
Fitchburg Public Library hosts Wisconsin Film Festival preview
FITCHBURG, Wis. — The 28th Wisconsin Film Festival is coming up in just a few short weeks, and a local library is helping get the word out.
The Best Subscription-Free Home Security Cameras I've Tried
You don’t have to upload your video to the cloud or pay a monthly fee to secure your home. These security cameras record locally.
Game Preview: Carolina Hurricanes @ Pittsburgh Penguins 3/22/2026
Who: Carolina Hurricanes (44-19-6, 94 points, 1st place Metropolitan Division) @ Pittsburgh Penguins (35-18-16, 86 points, 2nd place Metropolitan Division) When: 3:00 p.m. eastern How to Watch: Locally broadcast on Sportsnet Pittsburgh and FDSN South, streaming on ESPN+ Pens’ Path Ahead: Quality opponents await in the next week; the Pens host Colorado on Tuesday, an Avs team […]
‘Bet on the most wild things’: After sports gambling, prediction markets open door for all wagers
Black Family Wellness Expo brings people together for day of health education
The Black Family Wellness Expo returned to Roselawn Saturday.
Utica University Science Fair Inspires Young Scientists
Young scientists from local middle and high schools gathered for the 47th annual Utica University Regional Science Fair.
Barber reflects on shooting outside of his business
A man was shot and killed outside a local business in Youngstown’s first homicide of the year yesterday afternoon.
City of Santa Barbara Seeks Nominations for 2026 Business in Art Award
Nominations are now open for the 2026 City of Santa Barbara Business in Art Award, for local businesses that support artists
Musicians’ union hosts free health clinic in Treme
Local chapter of American Federation of Musicians offers free screenings to working entertainers
Farmers and rural community members can access free mental health resources
KGAN CBS 2 and KFXA Fox 28 provide local news, weather forecasts, notices of events and items of interest in the community, sports and entertainment programming for Cedar Rapids and nearby towns and communities in the Corridor and throughout eastern Iowa, including Iowa City, Waterloo, Dubuque, North Liberty, Coralville, Marion, Morengo, Williamsburg, Washington, Tiffin, Tipton, Solon, Mount Vernon, Lisbon, Central City, Urbana, Independence, Manchester, Dyersville, Oelwein, Cedar Falls, Waverly, Evansdale, Guttenberg, West Union, New Hampton, Decorah, Waukon, Maquoketa, Sigourney, Fairfield, Grundy Center, La Porte City, Dysart, Fayette, Elkader, Strawberry Point and Belle Plaine.
Local Business Spotlight: Educational Foundation of AACPS
The Education Foundation of Anne Arundel County Public Schools is helping bridge gaps, support innovation, and create new opportunities for students and educators throughout the county. In this wee…
Ancient DNA reveals a farming shift that pushed a society to the brink
A new study reveals that farming in Argentina’s Uspallata Valley was adopted by local hunter-gatherers rather than introduced by outside populations. Centuries later, a stressed group of maize-heavy farmers migrated into the region, facing climate instability, disease, and declining numbers. Despite these pressures, there’s no sign of violence—instead, families stayed connected across generations, using kinship networks to survive. The research shows how cooperation, not conflict, helped communities navigate crisis.
Community's Choice Awards spotlight: Oliv Epicurean Grill
Local favorites don’t nominate themselves. Volusia-Flagler Community’s Choice Awards nominations are in the final days.
Community's Choice Awards spotlight: Rockledge Gardens
The Brevard Community’s Choice Awards are picking up steam. Have you nominated your local favorites yet?
Community's Choice Awards spotlight: Affiliated Dermatologists
Milwaukee Top Choice Community’s Choice Awards nominations are almost done. Don’t ghost your favorite local businesses.
Sacramento businesses recover after string of burglaries; 1 suspect arrested
Sacramento police have arrested a man believed to be connected to 11 burglaries affecting local businesses, as authorities work to prevent further incidents.
We should all be playing pothole politics
Living in the ‘Potswolds’ has made me one of the Angry Local People pointing at our damaged roads
‘Hearing a lot from military families’: Local mental health provider reports surge in calls since conflict in Iran began
Since Feb. 28, what officials describe as an escalation in hostilities involving the United States, Israel and Iran has had ripple effects across the United States, from the stock market to gasoline prices and residents’ mental health.
Downtown Chico business owner voices concerns over street closures for events
A DOWNTOWN CHICO MERCHANT IS EXPRESSING CONCERN OVER THE IMPACT OF STREET CLOSURES FOR EVENTS -- ON THEIR BUSINESS. ACTION NEWS NOW REPORTER BELLA BARBOSA REPORTS FROM DOWNTOWN CHICO { "@context": "https://schema.org", "@type": "VideoObject", "name": "Downtown Road Closure Dilemma", "description": "A DOWNTOWN CHICO MERCHANT IS EXPRESSING CONCERN OVER THE IMPACT OF STREET CLOSURES FOR EVENTS -- ON THEIR BUSINESS. ACTION NEWS NOW REPORTER BELLA BARBOSA REPORTS FROM DOWNTOWN CHICO", "thumbnailUrl": "https://bloximages.newyork1.vip.townnews.com/actionnewsnow.com/content/tncms/assets/v3/editorial/c/47/c47e26d6-03c3-5f35-bf49-37925ab603d7/69bdedc4eb57d.image.jpg", "uploadDate": "2026-03-20T17:45:00-07:00", "contentUrl": "https://cdn.field59.com/KHSL/1774053903-6e1ef36dd09fbebf020833aee86b60da3b3cca3f_fl9-720p.mp4" } CHICO, Calif. - A downtown Chico business owner is voicing concerns about the impact of street closures for events on local shops. Leann Powell, owner of The Peddler’s Closet, expressed concern about events closing down streets downtown and bringing in food trucks and other shops’ products that directly compete with the brick-and-mortar stores in downtown Chico.Powell said an upcoming event held on a Saturday has brought up concerns for her and other business owners downtown, due to it being a busy day for businesses. "We're already struggling, and then to bring in more businesses on top of our businesses and shut our streets down is absolutely devastating," said Powell.Powell noted a decline in business during events like the Thursday Night Market, where street closures allow outside vendors to set up shop. She shared that while organizers for these types of events often offer booths to local businesses, it does not alleviate the burden."I don't really feel like that's a solution because you're bringing in other businesses, you're shutting the streets down. Yes, we can go down and set up a space, but then you've gotta pay somebody to run that space, plus run your own business for the day, and it's really not, it's really not helpful for us," said Powell.Applying for a street closure permit in Chico involves approval from the Public Works Department, the Chief of Police, and the Fire Chief. Permits can be denied only under a handful of circumstances, such as interference with first responders, previously scheduled construction, or existing permits for the same space.Mayor Kasey Reynolds addressed the issue, saying the city council has tasked staff with reviewing the municipal code for street closure permits with the goal of finding ways to minimize negative impacts on local businesses during events.Reynolds mentioned that any recommended changes might require further direction from the city council, depending on the extent of any changes recommended. googletag.cmd.push(function() { googletag.display('ad-1514992'); });
Report: Panthers agree to terms with local free-agent LB
The Panthers are reportedly signing an Anderson, S.C. native and former All-Sun Belt selection.
Brad Galli, longtime sports anchor at WXYZ, is leaving the station
Brad Galli has been with WXYZ, Channel 7, for 15 years. He is leaving at the end of April.
Local hopefuls Chip Honcho, Golden Tempo headline field in 113th Louisiana Derby
Click here to view this article from NOLA.com.
2026 Washington County high school spring sports central
Here are links to all of our Washington County high school spring content and team records and scores for baseball, softball, lacrosse and tennis.
What's going on with the mail? Delays still common after audit, residents say
A year after an audit at Louisville's postal facilities began, residents and business owners say they've seen no improvements.
Yale Surgery Launches Health Career Collaborative–New Haven to Mentor Local High School Students
The Department of Surgery has launched the Health Career Collaborative (HCC)–New Haven, a mentorship program connecting local high school students with surgeons
March Madness boosts local businesses in WNY
BUFFALO, N.Y. (WIVB) — Basketball fans have been flooding local bars and restaurants in Buffalo as the first of the March Madness games are underway Thursday night at KeyBank Center. “I…
Librarians seek continued funding from Congress to support local libraries
Librarians are breathing a temporary sigh of relief after President Trump signed the 2026 federal budget last month
Tooele business owners worry proposed road project could negatively impact daily operation
A proposed road project aimed at improving safety has drawn mixed reactions from local business owners.The Utah Department of Transportation, along with Tooele
Brooklyn businesses, consumers feeling the pinch from soaring oil prices
The soaring crude oil prices continue to push up the price at the pump, but it's also impacting everything from airfare to farmers, and products you buy at the store.
Kemi Badenoch channels her fantasies as she launches the Tories’ local election campaign
This wasn’t just a mean-spirited version of Britain, it was also positively deranged
True Bill Talk: Prosecution & Politics
The March 14 episode of True Bill Talk shifts the podcast’s focus from its typically local level to a national one. Nelson Bunn is the Executive Director of the National District Attorneys Association (NDAA), an organization that influences the policies of thousands of prosecutors across the country. In a conversation with host Alissa Marque Heydari, […]
Sam Wilson to officially kick off Clearwater City Council campaign
The host committee includes a slate of local GOP leaders, from City Council members and County Commissioners to members of the Legislature.
Mathews Local School board freezes coach salaries, no sports cuts
Superintendent Russell McQuaide decided tonight that the programs can stay, but warned that diminishing funding will force them to make tough decisions in the future.
Kansas bill could change rules for home-based businesses
Kansas lawmakers are debating HB 2343, a bill that would limit local regulation of home-based businesses, sparking debate over local control.
‘Welcome Back Babe’ event supports women-owned businesses impacted by winter storm
One local business owner is holding a special fundraiser for women-owned businesses impacted by the January winter storm.
From Italian food to used cars, here are six businesses that recently closed
Some closures are national chains, while others were locally owned.
‘Pride, not politics’: local Venezuelans express pride, hope after first World Baseball Classic win
Venezuela’s 3-2 upset of the United States team came at a tense political moment between the two nations.
Local restaurateur buying out Westover Taco to open N. Va’s first women’s sports bar
Women's sports fans could soon have a bar of their own in Arlington. Sarah White, a longtime local restaurateur and partner at Westover Taco, is in the process of buying out of the taqueria at 5849 Washington Blvd. After that? "I'm transforming it into Northern Virginia's first women's sports bar," White told ARLnow. As the
FNC acquires McPherson-based farm management business
Farmers National Company has acquired a Kansas-based farm management division to help provide sustainability for ag operations. FNC says the purchase from Peoples Bank and Trust in McPherson, Kansas, will give producers access to specialized management, local knowledge, and resources to help maintain profitability for producers. Grant Fitzgerald, Senior Vice President of Farm and […]
Local Spotlight | ArchWell Health Brings a New Approach to Senior Care
Local spotlight is joined by Dr. Doron Schneider, Market Medical Director at ArchWell Health.
Small Business Focus: Does AI keep you up at night?
Artificial intelligence is quickly becoming one of the most valuable tools available to small businesses and entrepreneurs — and BizLaunch is bringing that opportunity to the local business community with an upcoming in‑person workshop, “AI Advantage: Creating Winning Proposals With Smart Tools.” Led by the expert consultants at Revby, the program will explore how AI
TNA WRESTLING AND EUROSPORT INDIA ANNOUNCE NEW MULTI-YEAR EXCLUSIVE PROGRAMMING AGREEMENT
The Deal Includes the Popular Localized Hindi-Language Series ‘Pehlwani Patakha’, as well as Exclusive TNA+ Specials & Iconic Content from TNA’s Expansive Library Boasting Classic Matches from Some of the Sport’s Most Legendary Figures
Local farmer says entering politics 'shouldn't be daunting'
In part 2 of NEPM's series on newcomers entering politics, Easthampton, Mass., poultry farmer Karl Prahl reflects on how losing a campaign pushed him into community service.
Local farmer says entering politics 'shouldn't be daunting'
In part 2 of NEPM's series on newcomers entering politics, Easthampton, Mass., poultry farmer Karl Prahl reflects on how losing a campaign pushed him into community service.
Local farmer says entering politics 'shouldn't be daunting'
In part 2 of NEPM's series on newcomers entering politics, Easthampton, Mass., poultry farmer Karl Prahl reflects on how losing a campaign pushed him into community service.
Illinois businesses shift into growth mode after strong 2025
Local companies are confident after surviving years of high interest rates, inflationary pressure and tariff uncertainty, says a new BMO outlook.
11Alive
WXIA (Atlanta) — 11Alive is your source for breaking news, Georgia weather, traffic, and live coverage in Atlanta and across the metro area. Get the latest updates from the 11Alive team — from major local headlines and investigations to severe weather, community stories, and the moments everyone’s talking about. Watch live newscasts, stream breaking coverage, and catch up on the top stories shaping Atlanta, Marietta, Sandy Springs, Decatur, and surrounding communities. Subscribe for: • Atlanta breaking news + live updates • Georgia weather forecasts, storms, and severe weather alerts • Investigations and accountability reporting • Community stories across the metro area • Major events, sports, and local explainers WXIA / 11Alive — Atlanta news and weather, live and on demand. 🔗 More: https://www.11alive.com
10,000 unionized Corewell Health East nurses vote to authorize strike
Months of negotiations between the Teamsters Local 2024 union representing 10,000 nurses and Corewell Health East have yet to yield a new contract.
10,000 Teamsters Nurses at Corewell Health East Authorize a Strike
(WASHINGTON) – Registered nurses at Corewell Health East, represented by Teamsters Local 2024, have voted by nearly 90 percent to authorize a strike. The 10,0
KING 5 Seattle
KING 5 News (NBC Seattle) Seattle Leading Local News: Weather, Traffic, Sports & More See Seattle through new lens with our flagship YouTube series, Local Lens Seattle! [KING 5 Media Group, a TEGNA company]
Penny for your thoughts on how to round cash payments
As the U.S. says goodbye to pennies, Washington lawmakers have reached a solution for how local businesses should handle cents in cash transactions.
10,000 Corewell Health East nurses across nine Michigan hospitals vote to authorize strike
Nurses at Corewell Health East, represented by the Teamsters Local 2024 union, voted on Tuesday to authorize a strike by a nearly 90% margin. The union includes around ten-thousand nurses across nine hospitals and campuses throughout southeastern Michigan, according to a press release from the union. “This overwhelming strike vote shows that nurses are done […]
Mark your calendars: Weekly sports schedule for March 17-22
Take a look through the weekly sports schedule for the Central Coast, and make your plans to get out and attend, to support local sports programs. Read our coverage online
Chicago business conference to help local entrepreneurs
A Chicago business conference wants to help local entrepreneurs.
Storm science: What fuels severe weather
Severe storms threaten North Carolina, as research shows atmospheric conditions fueling tornadoes and thunderstorms are becoming more common across the Southeast.
Houston businesses welcome spring break crowds despite online calls for visitors to stay away
Houston business owners say Spring Break visitors are boosting tourism and the local economy despite online calls for travelers to stay away.
Boost your small business with this resource fair
WACO, Texas (FOX 44) – Small businesses are the engine of the local economy – and later this month in Waco, there’s an event designed to help them start, grow and succeed. The CenTex Hispanic Chamber ...
Two local developers in mix for I-95 service area redevelopment
Two local developers have submitted proposals to transform the two liquor stores off Interstate 95 in Hampton into service areas after the process was put in place by Gov. Kelly
WKYC Channel 3
WKYC (Cleveland) is your source for breaking news, Northeast Ohio weather, traffic, and live coverage in Cleveland and across the region. Get the latest updates from the WKYC team — from major local headlines and investigations to severe weather, community stories, and the moments everyone’s talking about. Watch live newscasts, stream breaking coverage, and catch up on the top stories shaping Cleveland, Akron, Canton, and surrounding communities. Subscribe for: • Cleveland breaking news + live updates • Northeast Ohio weather forecasts and severe weather alerts • Investigations and accountability reporting • Community stories across the region • Major events, sports, and local explainers WKYC — Cleveland news and weather, live and on demand. 🔗 More: https://www.wkyc.com/
First case of severe mpox disease reported in major city: ‘Life-threatening’
First severe mpox clade I case identified in NYC resident who traveled abroad. Health officials say local transmission risk remains low for the community.
Aspen Valley Health partners with electronic health record platform
Aspen Valley Health has announced the launch of an Epic Connect partnership, aiming to shift how independent rural hospitals access advanced healthcare technology in alignment with local governance.
Free Health Screenings & Safety Demos Scheduled For Thursday
Emergency responders and health care providers are hosting a free community event this week for local residents.
Call for Entries: Globee® Awards for Business Invite Local and Small Businesses Across the United States to Nominate Their Achievements
The Globee® Awards for Business, part of the Globee Awards' portfolio of merit-based and data-driven business recognition programs with worldwide participation, are now accepting entries and invite local and small businesses across the United States to nominate their achievements.
Downtown Seattle Association says business taxes are pushing out employers
Jon Scholes urges reduced taxes for Seattle businesses to retain employers and boost the local economy.
Abilene business expo to offer connections for growth this month
More than 170 local businesses will gather at the Abilene Convention Center this month for the 2026 Business Expo.
Small Businesses Are Pushing Back Against Private Equity
Touting local and family-owned credentials, Main Street companies say they’re fending off sometimes multiple inquiries a day from PE firms.
Reports: some 9/11 WTC health staffers reassigned to ICE, other roles
The Senate’s top Democrat joined a group of local Republican lawmakers seeking answers amid reports that 9/11 World Trade Center health fund program workers are being reassigned to other agencies, including U.S. Immigrations & Customs Enforcement. “It would be bad enough if they just reduced the number. That would be horrible enough,” Senate Minority Leader Chuck Schumer (D-New York) told…
UC Health opens $10M center billed as world's most advanced
The C-STARS facility will train 300 Air Force medical teams annually. UC Health has trained more than 5,000 Air Force medical professionals since 2002.
Bain Capital to Acquire Australian Wealth Management Business
Bain Capital will pay more than US$349 million to acquire an Australian wealth-management business from local investment manager Perpetual.
YVCF habitat fund awards 3 grants targeting invasive weeds, river health and post-fire recovery
The Wildlife Habitat Improvement Local District Endowment Fund has awarded three grants to support habitat projects across Routt County, backing work on invasive weeds, river health and post-fire forest recovery, according to a statement released...
Movie filmed in San Diego County starring Leonardo DiCaprio up for ‘Best Picture’ at Oscars
"One Battle After Another", a movie filmed in San Diego County, is nominated for "Best Picture" at the 98th Academy Awards and has injected nearly $7 million into the local economy.
Public health alert issued for frozen meat products sold at popular retailer
The Food Safety and Inspection Service issued a public health alert for frozen ready-to-eat meat products sold at a popular retailer.
AMD unveils OpenClaw to run AI agents locally on Ryzen and Radeon hardware
The effort is part of AMD's broader Agent Computer initiative, which argues that the future of AI isn't limited to remote infrastructure. Instead, it envisions a world...
Statesboro Business Commission to host information session March 26
The City of Statesboro Business Commission will host “Doing Business in Statesboro,” an information session for local small business owners and entrepreneurs, on Thursday, March 26, 2026, from 6:00 p.m. to 7:30 p.m.
Local couple’s honey business buzzes on national TV
A local couple — who are Indian Lake alumni — are experiencing swift, sweet success after their products debuted last week on the popular cable […]
As S.F. House hopefuls campaign, one is on more voters’ minds
Supervisor Connie Chan and former tech engineer Saikat Chakrabarti face a challenge in overcoming state Sen. Scott Wiener’s years of engaging local voters, columnist Joe Garofoli writes.
5 local schools earn top Ohio award from Gov. DeWine
Schools in five local districts have earned the Ohio Governor’s Science of Reading Champions Award.
The founder of $100M brand Late July and Nixie started selling $1 cookies at 12 and learned the snack trade from the founder of Cape Cod chips—her dad
Nicole Bernard Dawes, the founder of Late July and Nixie, got her start in business selling $1 cookies at local delis—the lessons she learned from the $500 summer hustle led to multimillion-dollar success.
Local contractors top national rankings; LSU professors honored for groundbreaking research
Here are some of the recent awards and special recognitions received by leaders at south Louisiana businesses and nonprofit groups.
France: Far-right strength put to test in local elections
Voters in France are heading to the polls in local elections seen as a litmus test for next year's presidential vote. A main focus will be the mayoral contest in Paris.
Tinkatink Community Day April 2026: Shiny Odds, Bonuses & Gigaton Hammer Tinkaton
Trainers, get hyped! The next Community Day of 2026 stars Tinkatink, the Metal Hammer Pokémon! Join the event on Saturday, April 11, 2026, from 2:00 p.m. to 5:00 p.m. local time to enjoy 2x catch Candy, increased Tinkatink spawns, and a chance to encounter Shiny Tinkatink. Evolve Tinkatuff during the event—or up to four hours […]
Chiefs take care of business versus rival Americans in 7-2 victory
The Spokane Chiefs dominate the Americans 7-2.
Business Bulletin: Stone Hill appoints; Kutis gives; CMT celebrates
Catch up on local business awards, expansions and milestones.
Downtown Roanoke bars say St. Patrick’s Day brings some of their biggest business of the year
Street party, parade draw crowds to local breweries and bars
Durham businesses brace for big night as top-seeded Duke seeks ACC repeat against Virginia
Shifting police approach to enforcing psychiatric holds in Sonoma County can leave loved ones at a loss and those in crisis at risk, advocates say
Involuntary mental health holds have been one option to ensure someone in crisis, and deemed a danger to themselves, gets help. But increasingly, local police are refusing to carry out those holds.
Park City Main Street reopened following report of bomb inside local business
Businesses along Park City’s Main Street were evacuated Saturday afternoon following reports that a bomb had been planted inside the Egyptian Theater.Lt. Daniel
Miami’s Community Newspapers hosts Small Business Expo
Miami’s Community Newspapers, with the Miami-Dade Strategic Procurement Department, hosted a Small Business Expo in its South Miami offices on Tuesday, Feb. 17, attended by local government and...
Hundreds of students compete in Regeneron Westchester Science and Engineering Fair
Participants get the opportunity to showcase their research and have their work judged by local experts in the field.
Christ Hospital Health Network expands women's care with new Greater Cincinnati site
The 4,551-square-foot facility is scheduled to begin seeing patients March 16.