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WHO updated recommendations on HIV clinical management: recommendations for a public health approach
This document provides an overview of the updated World Health Organization recommendations for HIV clinical management, which focus on optimizing antiretroviral therapy, preventing vertical transmission, and enhancing tuberculosis prevention among individuals with HIV. These updates are intended to support global initiatives aimed at ending AIDS as a public health threat by 2030. Key changes include the introduction of new antiretroviral drugs and regimens, revised postnatal prophylaxis and breastfeeding guidelines for managing infants at risk of vertical transmission, and the endorsement of shorter tuberculosis preventive treatments to improve efficacy and adherence. The recommendations are designed to simplify and advance HIV care, promote equity, and contribute to improved health outcomes and quality of life for individuals living with HIV. The updated guidance will be incorporated into the forthcoming revision of the antiretroviral therapy chapter within the Consolidated Guidelines on HIV Prevention, Testing, Treatment, Service Delivery, and Monitoring: Recommendations for a Public Health Approach.
This new 3D chip could break AI’s biggest bottleneck
Researchers have created a new kind of 3D computer chip that stacks memory and computing elements vertically, dramatically speeding up how data moves inside the chip. Unlike traditional flat designs, this approach avoids the traffic jams that limit today’s AI hardware. The prototype already beats comparable chips by several times, with future versions expected to go much further. Just as important, it was manufactured entirely in a U.S. foundry, showing the technology is ready for real-world production.
Sony WF-1000XM6 rears its head as launch information surfaces in new leak
The long-awaited Sony WF-1000XM6 has reappeared before the end of the year in a new leak. This time, a retailer has hinted at availability and launch colour options ahead of schedule.
State Department imposes sanctions on former EU official, disinformation group leaders for ‘censorship’
The US State Department on Tuesday imposed visa sanctions on a former top European Union official and employees of organizations that combat disinformation for alleged censorship – sharply ratcheting up the Trump administration’s fight against European regulations that have impacted digital platforms, far-right politicians and Trump allies, including Elon Musk.
Analysis: Extreme redactions undercut Epstein files release
Rather than settling matters, the government’s release of the Epstein files has had the opposite effect.
In Memoriam: Remembering those in politics, culture and media who died in 2025
Meet the Press NOW looks back at the icons in politics, culture and media who we lost in 2025.
Fresno approves new management deal for Convention and Entertainment Center
A newly approved three-year management agreement signals for the Fresno Convention and Entertainment Center pairs national venue operators charged with driving events, tourism and revenue while addressing operational costs, labor relations and downtown activation. Leaders
Paul Mauro on Gene Simmons' advice about politics: I didn’t see this coming
‘The Five’ discusses KISS rocker Gene Simmons’ message to Americans to stay out of other people’s politics.
Galaxy Z TriFold is probably durable enough, hinge gives way after 150,000 folds in torture test [Video]
Samsung’s brand new Galaxy Z TriFold form factor has arrived and, of course, one of the big questions around it...
Lions practice report: Detroit updates injury outlook vs. Vikings
The Lions released their Tuesday practice report, updating Detroit's injury outlook at the Minnesota Vikings.
Plant science with a twist
From morning glories spiraling up fence posts to grape vines corkscrewing through arbors, twisted growth is a problem-solving tool found throughout the plant kingdom. Roots “do the twist” all the time, skewing hard right or left to avoid rocks and other debris. Scientists have long known that mutations in certain genes affecting microtubules in plants can cause plants to grow in a twisting manner.
US health agency to negotiate prices for GLP-1 weight-loss drugs
The U.S. Centers for Medicare and Medicaid Services said on Tuesday it will negotiate drug prices with manufacturers of GLP-1 medications, in an attempt to expand access to the weight-loss treatments.
Nicki Minaj’s Embrace of Trump-Era Politics Has Fans Asking Questions
The Trinidad and Tobago-born hip-hop artist's motives are under scrutiny.
4 takeaways from the latest batch of the Epstein files
The Justice Department has released a new batch of documents related to convicted sex offender Jeffrey Epstein – documents that include many more mentions of President Donald Trump than last week’s dump.
Entertainment venues merge into one space
BY KADIE TAYLOR THE OBSERVER OPELIKA — Axe Marks the Spot and the Opelika Rage Room are teaming up to provide one location for community fun. With the renovations completed, the business owners are working to reorganize and best accommodate customer fun in the shared space. “I talked with Alex from Rage Room, and we […]
Science funding was hit in 2025. What does that mean for the future? : Consider This from NPR
2025 was a hard year for science. The Trump administration upended federal funding for all kinds of scientific pursuits, slashing budgets across agencies like NASA, NIH and NOAA. NPR's Rob Stein and Katia Riddle spoke to scientists and officials who worry that those cuts could cause the United States to lose its competitive edge as a global hub for research and innovation, and steer future generations away from careers in science. For sponsor-free episodes of Consider This, sign up for Consider This+ via Apple Podcasts or at plus.npr.org. Email us at considerthis@npr.org.This episode was produced by Michael Levitt, with audio engineering by Zo vanGinhoven. It was edited by Sarah Handel, Scott Hensley and Amina Khan. Our executive producer is Sami Yenigun.
Logan Paul drops $5.3M on a Pokémon card, tells young investors to ditch the stock market
Logan Paul paid $5.3 million for a rare Pokémon card and believes young investors should consider alternatives to traditional stock market investing.
Today's NYT Connections: Sports Edition Hints, Answers for Dec. 24 #457
Here's today's Connections: Sports Edition answer and hints for groups. These clues will help you solve The New York Times' popular puzzle game, Connections: Sports Edition, every day.
AWOL Vision LTV-3500 Pro: Ultra Short Throw Projection for Home Entertainment
If you're looking to set up an immersive, cinema-style home theater, AWOL Vision offers an all-in-one option worth considering.
Scientists from UChicago, other institutions discover bizarre lemon-shaped planet orbiting neutron star
Earth's seasons vary wildly, even at the same latitude, new research finds
Earth's seasons look very different at locations not far from each other, 20 years' worth of satellite data reveals.
Fantasy Football Championship-Round Tips: Advice to help you secure the trophy in Week 17
RAM Prices Are So Bad, PC Builders Are Telling Consumers to BYO Memory
Hopefully you have a few sticks of DDR5 lying around.
TPUSA’s America Fest Conference Showcased the Right’s Civil War
Prominent conservative influencers and lawmakers sparred at TPUSA's America Fest, it's first major conference since the murder of Charlie Kirk.
Strengthening its mid-Florida presence, Moss acquires Ellison Construction
'We found a partner that values culture, collaboration and the community as much as we do.'
Bill from Rep. Deluzio targets 'ripoff' of costly sports stadiums hot dogs and beer
As President Donald Trump calls affordability concerns a “hoax” and Democrats look to highlight the issue in the upcoming midterm elections,...
A Daring Scene on Broadway This Season Has Audiences Talking, in More Ways Than One
NEW YORK (AP) — On any given evening as the lights come up on Act 2 of “Liberation,” Bess Wohl's intergenerational Broadway play about a women’s consciousness-raising group, you can hear supportive cheers of “Whoo!” and “Yeah!” — and sometimes, a round of applause. All before a single word has been ...
Mike Tomlin on D.K. Metcalf taking swing at Lions fan: 'Don’t condone the behavior, but I support D.K.'
New poll finds Americans in sour mood on economy and US leadership
A wide-reaching new poll finds Americans are approaching 2026 with negative opinions about the economy, the direction of the nation and its leaders.
The Supreme Court’s most consequential term yet?
Opry Entertainment Group Unveils Star-Studded New Year's Eve Celebrations at Nashville Venues
Opry Entertainment Group is ringing in 2026 with an unforgettable lineup of New Year’s Eve events across Nashville’s most iconic venues.
Shake Shack rolls out health-oriented menu
The ‘Good Fit’ lineup of curated items focuses on protein while also offering low-carb, vegetarian, and gluten-free options
27-year-old boosted his income from $50,000 to $432,000 at Amazon in 5 years—it allowed him to quit and start his own business
Nabeel Khan was methodical in building his career at Amazon, rising the ranks quickly from operations manager to project manager to product manager.
Oklahoma City, fans across the state will never forget the year of sports in 2025
KOCO 5 Sports Director Bryan Keating replays some of the many major and championship sports moments from 2025 in Oklahoma City
Tiny implant 'speaks' to the brain with LED light
By directly communicating with the brain, a new wireless device could someday help restore lost senses or manage pain without medications, its developers say.
Year in review: Trump's economy : The NPR Politics Podcast
As we approach 2026, the NPR Politics Podcast is taking a look back at the year that was in different political areas. Today, we look at President Trump's handling of the economy, including his tariff policy.This episode: political correspondent Sarah McCammon, White House correspondent Danielle Kurtzleben, and chief economics correspondent Scott Horsley.This podcast was produced by Casey Morell & Bria Suggs, and edited by Rachel Baye. Our executive producer is Muthoni Muturi.Listen to every episode of the NPR Politics Podcast sponsor-free, unlock access to bonus episodes with more from the NPR Politics team, and support public media when you sign up for The NPR Politics Podcast+ at plus.npr.org/politics.
Trump reveals more about Gov. Jeff Landry’s envoy role: ‘Greenland’s a big deal’
The president said Greenland is important for national security reasons, and called Landry a “dealmaker-type guy.”
College football bowl and CFP picks, predictions: Legendary Vegas expert reveals best bets
SportsLine CFB expert Bruce Marshall reveals best bets for every College Football Playoff and bowl game
Wisconsin judge sends Slender Man attacker back to mental health institution after group home escape
MADISON, Wis. (AP) — A Wisconsin woman who almost killed her sixth-grade classmate to please the fictional horror villain known as Slender Man was ordered back to a state psychiatric hospital Tuesday after she escaped from her group home last month.
An LSU professor’s tips for responsible AI adoption in business
As artificial intelligence tools become more accessible, business leaders across a range of industries are having to work out how to adopt them without putting sensitive information or the trust o… Already an INSIDER? Sign in. We are glad you enjoy reading Business Report. Continue reading this story and get ACCESS to all our content […]
“My goal is to eliminate every line of C and C++ from Microsoft by 2030” — Microsoft bets on AI to finally modernize Windows
A distinguished engineer outlined a "previously unimaginable" plan to rewrite millions of lines of code using AI agents and algorithms.
FanDuel SN channels could be sold as broadcaster scrambles for funds
If a sale falls through, Main Street Sports Group could ultimately be shut down following the current NBA and NHL seasons.
Latest Epstein files name Trump multiple times
In the more than 10,000 files released Tuesday, Jeffrey Epstein’s brother, Mark Epstein, said the sex trafficker was killed because he was going to name co-conspirators.
Samsung Unveils New Odyssey Gaming Monitor Lineup, Featuring World-First 6K 3D and Ultra-High-Resolution Displays
2026 Odyssey gaming monitor lineup introduces record-breaking refresh rates and resolutions for competitive gaming, including the world’s first 3D (6K resolution) glasses-free display
Do the Detroit Lions need big, sweeping changes?
Our latest Detroit Lions podcast episode discusses the Steelers loss and debates what changes are needed in 2026.
Klarna Sees Triple-Digit Spending Growth Across Entertainment, Experiences, and Automotive This Holiday Season
NEW YORK, December 23, 2025--Klarna, the global digital bank and flexible payments provider, today reports an increase in U.S. holiday spending beyond traditional retail, with consumers driving triple-digit year-over-year growth across entertainment (+130%), experiences (+115%) and automotive products (100%), such as vehicle maintenance and repairs, from December 1 through Monday, December 22, signaling a clear shift toward experiential and high-value practical purchases this season.
NFL Week 17 odds, lines, spreads: Picks, predictions, best bets today
SportsLine's model simulates every game 10,000 times and reveals its NFL picks today
The Philip Rivers comeback was wasted time for the Colts
Despite the best efforts of Philip Rivers, his comeback did not help the Colts' playoff aspirations.
Brand Innovators Outlook 2026: Entertainment
The entertainment industry faces a year of change and adjustment in 2026. New technologies and merger activity will keep movies, TV and live events in play. With the limitations of the COVID pandemic firmly in the rear-view mirror, the sector anticipates consumers will indulge in movies and live events, and brands will find new ways […]
Expiring Affordable Care Act subsidies to raise health insurance costs for thousands
WCIV ABC News 4, Charleston, South Carolina provides coverage of local and national news, sports, weather and community events in the region, including North Charleston, Mt Pleasant, Summerville, Hanahan, Goose Creek, Rantowles, Cottageville, St George, Moncks Corner, Jacksonboro, Ravenel, Cottageville, Walterboro, Sullivans Island, Dewees Island and Folly Beach.
Nine mental-health tips for a happier 2026
Regardless of any resolutions you may have for 2026, one thing is for sure: Everyone wants to have a happy new year.While losing weight or saving money may be great goals, the most straightforward path to happiness is caring for your mental and emotional health. A robust body of research shows that simple cognitive and behavioral strategies can reliably boost happiness and reduce stress – and they’re generally free and accessible to all.These strategies don’t have to be super time-consuming, but they do require intention: They only work if you do them.Here, psychologist Valentina Ogaryan, PhD, clinical director of the Simms/Mann UCLA Center for Integrative Oncology, shares her top tips for cultivating more calm, centeredness and happiness in the new year (or anytime):Make time for playPlay isn’t just for kids, and it’s far from frivolous. The National Institute for Play says engaging in silliness, fun and just-for-pleasure activities reduces stress and increases optimism and resilience. A recent review also found that play improves mental health.“Adults can benefit from play as much as children,” Dr. Ogaryan says, “not just as a reward, but something that helps regulate.”So go ahead and dance with your dog, build something with Legos, tell a joke, sing karaoke or do anything else that feels like fun. Don’t worry about being productive, just enjoy yourself. And, if you can, opt for more analog play, Dr. Ogaryan suggests, as a respite from our ever-more-digital world. Move your bodyWhether you dance, ski, do yoga, play pickleball, ride a bike, roller-skate, hike or lift weights, physical movement benefits overall happiness and well-being. A 2018 review study of more than 1.2 million adults in the U.S. found that doing any kind of exercise was “significantly and meaningfully associated” with better self-reported mental health.The sweet spot was 45 minutes of movement three to five times a week, but even short bursts of physical activity can boost brain health, according to the Centers for Disease Control and Prevention.“Movement helps support mood and regulate the nervous system,” Dr. Ogaryan says.Plus: exercise can improve sleep quality, and sleep is essential for mental health.Prioritize sleep“Sleep plays a major role in managing stress,” Dr. Ogaryan says. Research shows that lack of sufficient sleep increases the risk of various diseases, including depression.While stress can interfere with sleep, practicing good sleep hygiene can make logging ZZ’s easier. That means maintaining a consistent bedtime; keeping the bedroom cool, dark and quiet; and avoiding social media, news and stimulating shows before bed.Consume lessWe live in a consumer culture, inundated by endless streams of content and advertising everywhere we go, which makes it easy to get overstimulated.“Something really helpful for stress reduction is to simply consume less,” Dr. Ogaryan says – less news, less social media, less information, less noise, less screen time. “It’s about reducing the input,” she says.Consider setting a maximum number of news articles per day, for example, or a time limit on scrolling. Maybe even go device free for an afternoon or a whole day.Practice present-moment awarenessWith so much coming at us all the time, focusing on the here and now can make life feel more manageable, Dr. Ogaryan says: “When everything feels super overwhelming, when everything feels larger than life, let’s make our world a little bit smaller for that moment in time.”She suggests taking things one day, or even one hour, at a time. Ask yourself: What’s my next right action? Release the need to know how everything turns out and liberate yourself from having to handle everything right now. Let the future take care of itself and just focus on the current moment. Then the next one. Have a daily anchorFrom work to the daily commute to family and life responsibilities, our days can feel jam-packed. Dr. Ogaryan recommends creating a centering daily anchor that can fit into even the busiest day.Maybe it’s a 10-minute walk during your lunch break or mindfully enjoying your coffee in the morning. Let your anchor adapt to your needs each day, she says, but be intentional about using that time to ground yourself and calm your nervous system. You might even say to yourself, “I choose this walk to help me become centered,” or “My day already feels stressful, so I’m going to take the next 10 minutes to enjoy this cup of coffee, feel the warm mug in my hand and just be present.” Having an anchor won’t erase the busy-ness from your day, but it will allow you to approach it more calmly.Be kind to yourselfMost of us have a harsh inner critic in our heads who works overtime. But that critical voice only increases our stress, triggering the same fight-or-flight response as caustic words from another person.To feel happier, we need to replace that inner critic with a kinder, more compassionate voice, Dr. Ogaryan says. Studies show that self-compassion is a source of eudaimonic happiness – the kind of happiness associated with purpose and meaning in life.While our knee-jerk reaction may be to self-criticize – “How could you let it get to this point? You didn’t manage your time well and now the project is going to be late. You’re so inept.” – we fare better mentally by treating ourselves with kindness, like we would a friend. That might sound like, “You’ve got a lot on your plate, but you are capable and you’ll get it done. I believe in you.”We may think that speaking kindly to ourselves means letting ourselves off the hook, so we end up becoming lazy do-nothings. But research shows the opposite: People who are self-compassionate are more likely to try harder in the face of failure and ultimately reach their goals.You can thank your inner critic for its good intentions, but resolve to talk to yourself in a kind, compassionate voice.Connect with othersHumans are social animals built for connection. Stress can be isolating and cause us to withdraw, but connecting with others is a salve for the psyche, Dr. Ogaryan says.“We know that not all relationships are always easy, but if we can think about intentional, nourishing connection – even in really small doses – it could really help center us,” she says.Take a moment to laugh with your colleagues, hug your pet, have a conversation with a friend or smile at the barista making your coffee. A study found that even tiny interactions with casual acquaintances and strangers decreases loneliness and improves happiness and well-being.Seek supportIf you try these practices and happiness remains elusive, or if you can’t access the wherewithal to follow these tips, seek support from your physician or a therapist. Mental health conditions are among the most common health issues in the U.S. and around the world – more prevalent than diabetes or heart disease. One in five people in the U.S. experiences a mental illness each year, with depression and anxiety the most common, according to the National Institute of Mental Health.“We can all think about these tips,” Dr. Ogaryan says. “But it’s important to recognize if you’ve done everything you can and you’re still really struggling, it’s really important to seek help.”
Can Science Tell Us Why?
The field of science is filled with questions. But are we asking the right ones?
The disunity of science is a feature, not a bug
Mathematical models wield miraculous power, but mistaking them for reality has trapped science in a destructive quest for a “Theory of Everything.” Physicist and philosopher Ragner Fjelland argues that this leads to bloated, Frankenstein theories kept alive by clumsy, ad-hoc amendments, which reduce rather than boost science’s power. Fjelland calls for a radical shift in our attitude: we must reorientate towards creating entirely new theories, celebrating rather than lamenting disunity and diversity in science. Science, from the scientific revolution in the seventeenth century to the present day, has more or less developed in a “reductionist” way. The fundamental assumption is that all sciences may be ordered in a hierarchy that can be represented as an upside-down pyramid. At the top we find the human sciences, and at the bottom physics. Strong (or “ontological”) reductionism maintains that all theories at one level can be completely reduced to the lower level, all the way down to theories of atoms and elementary particles, or whatever is “at the bottom.” In the end, all diversity in the world can be unified in one fundamental theory. Hence it is called a final theory, or a Theory of Everything.One of the central figures in developing the idea of a Theory of Everything is the Dutch theoretical physicist Gerard 't Hooft, who received a Nobel Prize in physics in 1999 for his work. He emphasizes the non-empirical status of the theory:There exists no closely resembling alternative theory. This means that any slight change brought about in the rules would make the theory unlikely or inelegant. The theory will be a "package deal": take it, or leave it. This should hold both for the local laws and for the boundary conditions.This endeavor is not new. On the contrary, it goes all the way back to the birth of Western philosophy 2,500 years ago. The Babylonians made regular astronomical observations during a period of 600 years, from 747 BCE until 150 ACE. They developed mathematical techniques to predict astronomical phenomena, but they made no attempts at explaining them. However, the Greeks developed models, both material and theoretical, to explain the observed phenomena.The best example is Plato’s late dialogue Timaeus. Here he introduces a divine craftsman, the Demiurge, who has constructed the universe according to an original plan. Plato seems to have thought that the original plan is what is actually real, while the material world is merely an imperfect realization of it. He therefore does not, in the Timaeus, reconstruct the material universe, but the original plan, which can then be used to explain the material universe.Plato’s aim in producing a theoretical model is to reconstruct the original plan. That is what he carries out in Timaeus—and some modern physicists have embarked on the same project. For example, Einstein’s basic attitude is reflected in the title of Abraham Pais’ biography: “Subtle is the Lord...,” echoing Einstein’s comment, “Subtle is the Lord, but malicious He is not.” In an interview Einstein compared our situation to a child who enters a huge library. The child knows that someone has written the books, but he does not know the languages in which they are written. He suspects that there is a mysterious order, but he does not know what it is.___“We have all been working in what Husserl called the Galilean style; that is, we have all been making abstract mathematical models of the universe to which at least the physicists give a higher degree of reality than they accord the ordinary world of sensation.”Steven Weinberg, Nobel Prize in Physics (1979)___This Platonist view is contrary to a widespread impression of science, symbolized by the picture of the “father” of modern science, Galileo Galilei, with his telescope. According to this impression, Galileo liberated himself from the dominating metaphysics of his day—basically Aristotelian philosophy—and constructed a telescope that he directed towards the sky, showing that Jupiter has four moons. He also performed experiments with bronze balls rolling down inclined planes and found the law of freely falling bodies.However, in other cases Galileo emphasized the unreliability of our senses. It is easy to see why. He defended Copernicus’ heliocentric hypothesis. According to this hypothesis, we are not at rest at the center of the universe, but moving at a tremendous speed through space. Why don’t we observe this motion? Galileo praises Copernicus because “with reason as his guide he resolutely continued to affirm what sensible experience seemed to contradict.” In other places he directly refers to Plato. SUGGESTED VIEWING The quest for a final theory With Michio Kaku Galileo’s Platonism goes back to his early writings. In The Assayer, published as early as 1623, Galileo compared the universe to a grand book that is written in the language of mathematics, and “its characters are triangles, circles, and other geometric figures without which it is humanly impossible to understand a single word of it.” Therefore, things that cannot be described by mathematics—for example, colors, smells and odors—are not real. They are merely subjective.This division into subjective and objective, advocated by Galileo and his younger contemporary René Descartes, is normally associated with a mechanistic world view, which is regarded as the opposite of Platonism. When we reduce something to, for example, molecules and atoms, we move “downwards.” In contrast, the Platonist moves “upwards,” to abstract entities. However, it only shows that when we address fundamental questions, we should be careful in applying everyday spatial metaphors like “up” and “down.”___Nature is complex, and we cannot in general construct mathematical models that adequately describe the world.___The endeavor of finding a Theory of Everything has been heavily criticized. In 2006, the theoretical physicist Lee Smolin published “The Crisis in Fundamental Physics.” He argued that one of the most fundamental principles of science is that we should only regard theories as scientific if we have the possibility to show that they are false by experiments. Although he did not refer to Karl Popper, other critics have referred to Popper and argued that a theory is not scientific if it cannot be falsified (see for example Ellis & Silk 2014).These were not the first physicists to be anti-reductionists. In 1972, the journal Science published an article by the physicist Philip Anderson with the title “More Is Different.” This is the kind of article a scientist would normally write only after he has won a Nobel Prize. However, Anderson won the Nobel Prize for physics five years later, in 1977. The article is amazing, not primarily because it argues in favor of anti-reductionism in general, but because it argues for anti-reductionism within physics itself. Anderson’s conclusion was:At each stage entirely new laws, concepts, and generalizations are necessary, requiring inspiration and creativity to just as great a degree as in the previous one. Psychology is not applied biology, nor is biology applied chemistry.We may say that Plato started the “unity of science movement,” based on Euclidean geometry as the model of all knowledge. A distinguishing mark of geometry is that all possible constructions can be reduced to a few fundamental principles. We have to acknowledge that this approach has limitations. In general, we can easily model technological systems. In addition, we may construct simplified and idealized models that capture important aspects of systems, from various perspectives and for various purposes. But nature is complex, and we cannot in general construct mathematical models that adequately describe the world. In a complex system, each level has its distinct, emergent, properties that are characteristic of this level. Therefore, a complex system should be investigated at different levels and from different perspectives. Instead of exclusively pursuing a scientific ideal based on the unity of science, we should acknowledge the diversity—or even the disunity—of science.
New Health Ministry guidelines: Sperm bank donations from one donor limited to 12 families
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2025: Wealthtech that Helps Advisors Expand Their Business
Startups develop advanced AI and tech solutions for financial advisors, moving past simple automation to enhance business capabilities
MIT scientists strip cancer of its sugar shield
Scientists at MIT and Stanford have unveiled a promising new way to help the immune system recognize and attack cancer cells more effectively. Their strategy targets a hidden “off switch” that tumors use to stay invisible to immune defenses—special sugar molecules on the cancer cell surface that suppress immune activity. Early tests show it can supercharge immune responses and outperform current antibody therapies.
From the Texas Legislature: 5 big moves that shaped your life this year
Decisions in Austin reset taxes, schools, gaming and the balance of power across the state.
The culture war is consuming the Supreme Court
The Court’s overall docket is shrinking, even as it hears more and more cases dealing with Republican cultural grievances.
New batch of Epstein files released featuring more Trump mentions
New set of files released overnight into Tuesday
Key Wisconsin motor sports events for the 2026 racing season
With IndyCar, IMSA, Outlaws and High Limit, ASA, dirt late models and specials, Wisconsin racing has plenty to offer in 2026. Still no NASCAR though.
The best reality TV of 2025
Scandals, competitions and breakups are par for the course on reality shows, but this year also brought some tender moments that made for must-see TV.
How America’s Health Care System Broke in 2025
2025 exposed the consequences of political interference, rising costs, workforce strain, and unregulated AI.
Managing the politics of a holiday get-together
We live in a polarized nation, and sometimes, those varying political beliefs and opinions make their way to the holiday dinner table. It can be awkward and uncomfortable. So, how can we bring it all back together and appreciate one another’s company? WEMU’s John Stockwell went looking for answers and, as you’ll hear, found a number of them.
FPL GW18 Player Picks: Top Fantasy Options for This Week
Gameweek 18 is fast approaching, and Fantasy Premier League managers have very little time to make their moves. With fixtures coming thick and fast, choosing the right players could make all the difference. This article highlights players with the most promising runs of matches heading into Gameweek 18 and points out the options worth considering […]
IFLScience The Big Questions: Can Magic Be Used As A Tool In Science?
What do cybercrime, the placebo effect, and driving have in common? They can all be better understood with a bit of magic.
‘It breaks our heart’: These 30 business locations across Pa. are closing
The businesses on the list are located in 12 counties.
A veteran of news media business, Peter Stanton announces retirement
Peter Stanton has spent nearly his entire career in Worcester, working among independent news publications. He retires at the end of the year.
Central Indiana's Top 10 stories of 2025, from sports to Trump
The year in sports brought unlikely rises and dramatic falls. The year in politics shook Indiana's foundations. Here are the Top 10 stories of 2025.
The AI dating arms race: Dating apps are betting millions that you'll fall back in love with them
Dating apps like Tinder, Hinge, Bumble, and Grindr are investing in AI-powered matchmaking, hoping to fend off swiping fatigue.
Tough decisions for NJ on health insurance as 2026 cuts loom
Gov.-elect Mikie Sherrill and the Legislature will have to grapple with federal cuts to Medicaid, and hospitals warn of being deluged with patients.
CAN 2025: 3 teams chasing a historic first victory
3 teams in search of their maiden CAN winTanzania/@CAFAmong the eight teams competing this Tuesday, December 23 at the 2025 Africa Cup of Nations in Morocco, three sides are looking to make history. B...
HARMAN To Acquire ZF’s ADAS Business
Secures HARMAN’s strategic foundations in ADAS and centralized automotive electronics platforms to define the fast-growing SDV market
Critical n8n Flaw (CVSS 9.9) Enables Arbitrary Code Execution Across Thousands of Instances
Critical n8n flaw CVE-2025-68613 (CVSS 9.9) lets authenticated users run arbitrary code; versions 0.211.0–1.120.4 affected, patched in newer releases.
US bans new foreign drone models in a blow to Chinese giant DJI
A new rule by the Federal Communications Commission will make it impossible for US consumers to buy the next generation of foreign made drones.
A cheaper, easier-to-use version of Wegovy is coming to the US soon
Wegovy's new pill has been approved in the US, offering a needle-free option with a lower starting price than injections.
Report: DK Metcalf loses millions in guarantees following suspension
Metcalf’s two-game suspension is a bigger deal than we thought.
The Best of BoF 2025: Fashion and Sports Forge a Powerful Alliance
As the fashion world navigated a tough year filled with macroeconomic headwinds and deep consumer pessimism in key marketplaces, the sports industry proved to be a bit of a guiding light.
Jim Beam is pausing production at its iconic Kentucky bourbon distillery
Distilled spirits have seen a major decline in exports to big markets like Canada, and domestic consumption isn't making up for the shortfall.
Connections: Sports Edition hints for Dec. 23, 2025, puzzle No. 456
Welcome to Connections: Sports Edition Coach — a spot to gather clues and discuss (and share) scores.
Vikings vs. Lions Injury Report
See who's in and who's out for the Week 17 matchup between the Detroit Lions and Minnesota Vikings on December 25, 2025.
NFL Power Rankings entering Week 17: Ravens' disastrous season raises questions about John Harbaugh
The future of worldbuilding in entertainment
WEST VIRGINIA (WVNS) – New innovations in entertainment and content creation have changed the way users consume and interface with media. From games and film to music and interactive media, platforms have been leveraged to coincide with one another to paint a broader picture. Creators have said the days of standalone titles are giving way […]
Curiosity Blog, Sols 4750-4762: See You on the Other Side of the Sun
Written by Lucy Thompson, Planetary Scientist and APXS team member, University of New Brunswick, Canada
U.S. signs new health deals with 9 African countries that mirror Trump's priorities
Annual U.S. health funding to the nine countries has dropped 49% compared with 2024, while the nations must increase domestic spending and meet political conditions.
Trump denies Colorado disaster aid for wildfires, prompting accusations of ‘political games’
Colorado politicians on both sides of the aisle are pushing back after President Donald Trump’s administration denied two disaster declaration requests that would have unlocked federal funds for recovery efforts. Gov. Jared Polis said in...
Health Ministry tightens oversight as demand for sperm donations surges
Health Ministry updates sperm bank rules as demand rises and fewer people donate, capping families per donor at 12, tightening genetic screening, and new import standards to improve safe donations.
Trump bemoans destroyed reputations from Epstein files release in first public comments since DOJ release
Trump bemoans destroyed reputations as a result of Epstein files release
Amarillo small businesses rely on holiday sales for 75% of annual revenue, owners say
When consumers choose to spend their money locally, those dollars stay within the community. In Amarillo, small business owners are encouraging residents to sho
John Harbaugh addresses job security as Ravens' playoff hopes dwindle
Questions about Harbaugh's future in Baltimore are as loud as ever
Fantasy Football 2025: Waiver wire, Week 17 championship edition
Wading into the free agent pool for roster help
Justice Department’s heavy-handed redactions leave no one happy in the ‘Epstein files’ saga
The Justice Department’s release of the Epstein files — mandated by Congress to be completed last week — is still a work in progress.
Full-length Replay: First Things First
Nick Wright, Chris Broussard and Kevin Wildes offer their opinions on the day's sports stories.
Columbus Regional Health restricts visitors due to respiratory illness surge
Columbus Regional Healthcare has implemented new visitor restrictions due to increased spread of influenza, RSV and COVID-19.
Best Of: What Beards Tell Us About Power, Politics And How We See Each Other : 1A
Abraham Lincoln was the first U.S. president to sport a beard. For the next 50 years, whiskers were commonplace in the White House. But then, they went out of style.Now, Vice President JD Vance is the first executive branch leader in more than a century with a furry face.And others are following suit. From the Senate to the campaign trail, more and more men in politics are letting their facial hair grow free. But what does that tell us about masculinity, power, and how we see each other?Why did our politicians remain bare faced for so long? And what does the reemergence of whiskers in the White House represent?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.
30 Years of Standing for Science and Equity
This month, AVAC marked our 30th anniversary. Over three decades, the HIV field has evolved dramatically—but what we do, and why we do it, has remained constant: standing for science, equity, and community leadership, and ensuring evidence drives decisions that affect people’s lives. We’ve been able to do this work because of your partnership and […]
Google tells staff it will ramp up green card applications again in 2026. Here's who won't be eligible.
PERM applications at Google will ramp up in 2026, affecting visa holders seeking green cards and permanent residency.
Google tells staff it will ramp up green card applications again in 2026. Here's who won't be eligible.
PERM applications at Google will ramp up in 2026, affecting visa holders seeking green cards and permanent residency.
Congress flees town as health care premiums set to explode for millions of Americans in January
Congress failed to fix soaring health care premiums before leaving for recess, setting up a big political battle in 2026 as costs spike for millions.