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Iowa family finds strength beyond the gym after cancer diagnosis
URBANDALE, Iowa (KCCI) -- Azariah Townsend can barely reach the pull-up bar in his family’s home gym in Urbandale, but he already knows strength is not measured by height.
Early voting underway in Michigan
Early voting began Saturday, Oct. 24 in Michigan. County officials say the first day of early voting went well and more than half of mail-in ballots have already been returned.
Dunwoody to discuss adding two entertainment districts
The Dunwoody City Council will discuss adding two new entertainment districts – Georgetown and Jett Ferry – at its meeting on Monday, Oct. 26.
MedStar Health expert warns parents about illnesses affecting teens and college students
CBS News Baltimore spoke with an expert at MedStar Health about common illnesses among teens and college students, including mononucleosis, strep throat and skin infections.
Democrat Coumba Kebe wants to keep the politics out of the treasurer’s office
Political newcomer Coumba Kebe is the Democratic nominee for Indiana state treasurer. Kebe wants to keep the politics out of the office and build back trust with people.
Aleksandar Vucic concedes defeat in Serbia's parliamentary election, marking political shift
Aleksandar Vucic, who denounced the oppositional student movement as a foreign-led attempt to unseat him, led with virtually absolute power for 14 years.
Health West Chubbuck expands hours, adds X-ray services and two new providers
CHUBBUCK — Health West has announced that it has expanded the services offered at Health West Chubbuck and that it has added two new providers to its staff as well
Kenilworth's David Brearley 2026 Homecoming Photo Album
KENILWORTH, NJ – The Homecoming Dance was held on Friday, Oct. 16, and students were filled with energy and excitement as they left for the annual occasion held at David Brearley.To preserve the...
NH candidates for governor, U.S. Senate, Congress clash over...
At a Manchester forum, New Hampshire candidates clashed over housing, energy, healthcare and other costs as affordability emerged as voters’ central concern. ...
Editorial: Company mergers are causing more harm to the entertainment industry than good
Two weeks ago, Paramount officially completed its $110 billion purchase of the historic Warner Bros.
‘Masterplan’: Too lightweight to make an impact
Pretty faces can’t overcome ho-hum plotting
Kaine, Randall tour county's new Crisis Receiving and Stabilization Center
The Loudoun County Crisis Receiving and Stabilization Center's first day of operations on Oct. 22 included a tour by Sen. Tim Kaine, D-Va., and county Board of Supervisors Phyllis J.
Halloween evolved as a Frankenstein of cultural celebrations
The holiday has origins in Celtic, Roman and Catholic festivals and feasts, and mixed with other traditions as it spread.
After arts festival, San Francisco's Mid-Market businesses look for signs of a turnaround
Gina Hinojosa says there's "deep disappointment in both political parties" in Texas right now
BCM hosting special Nov. 13 show for America 250
BRISTOL — In partnership with The Crooked Road: Virginia’s Heritage Music Trail, Mountain Empire Children’s Choral Academy, and Theatre Bristol, the Birthplace of Country Music Museum is bringing together an
Union County Best of the Best Business of the Year Magnolia Renovations Joshua Andrews, owner
What was your reaction when you learned your business had been named Business of the Year?
China Star Entertainment (SEHK:326) Stock Looks Richly Priced As Its 8.6x Run Continues
China Star Entertainment has logged very strong multi year share gains, so the key issue now is whether the current price can be supported by the value of assets on its balance sheet. For anyone looking at the stock today, the immediate question is how that share price lines up against its book value. Over the past 3 years the stock has returned about 8.6x. This puts a lot of weight on whether the underlying equity in the business justifies this kind of move when you compare it with the...
Epic CEO Tim Sweeney lambasts “abhorrent” Steam AI Disclosure Policy claiming labels double as “political statement”
Epic Games CEO Tim Sweeney called Steam’s AI disclosure policy abhorrent, arguing that it exposes developers to backlash from anti-AI detractors. Valve has implemented and updated the policy since 2024, which states that AI-generated content, including artwork, text, music, and assets, excluding assistant tools, requires formal disclosure.
Sunday Puzzle: BRB
NPR's Ayesha Rascoe plays the puzzle along with Weekend Edition Puzzlemaster Will Shortz and WUOT listener Jordan Bogdan of Oak Ridge, Tennessee.
'Not a one-person job:' Bernardsville explores exit from Bernards Health Department
BERNARDSVILLE - Concerns about costs have led borough officials to consider cutting off decades-long services from the Bernards Township Health Department and switching to the Somerset County Health Department.
2 political experts question Chicago Mayor Brandon Johnson's tax proposals for 2027 budget
Cost of employer-sponsored health insurance rises again, survey finds
WASHINGTON — The cost of employer-sponsored health insurance increased again this year, as did the deductibles many people must pay before their plans begin covering most health care expenses, according
ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals
Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.
Rumored Lucia Actress Goes Viral After Dodging Swarm of GTA 6 Comments During Livestream
Manni L. Perez, the actress long rumored to be playing Lucia in GTA 6, has gone viral after dodging a swarm of comments from Grand Theft Auto fans during a recent livestream.
Stateliner Pride on Display: Phillipsburg Band and Alumni Unite at Halftime
Phillipsburg’s Stateliner band and alumni joined for a halftime performance celebrating school tradition, pride and community at Friday’s football game.
GO Health asks families to be lead-aware
BATAVIA — Area health departments are encouraging families to get the facts and get their children and homes tested for National Lead Poisoning Prevention Week.
Roots music fest fun in downtown Yadkinville
Click here to view this article from yadkinripple.com.
Nuthatches are rude: Ornithological observations from a recliner
I don’t know what age you’re supposed to start sitting in a recliner and looking out the living room window at the bird feeder, but I sure do like doing
Calvert liquor store gets license transfer; other business fined
New management will be taking over a liquor store in Dunkirk sometime in November.
Tickets on sale now for 49 Winchester's Charlottesville show next year
49 Winchester, a homegrown Virginia country rock band, is the first band announced for Ting Pavilion's 2027 lineup. Tickets are on sale now.
Clay Walker Christmas coming to NPAC Nov. 29
GREENEVILLE — Rumor has it … it’s shaping up to be A Clay Walker Family Christmas.
Local breakfast chain plans Derby expansion
The Easy Egg, a Wichita-based breakfast and lunch restaurant, recently announced plans to expand into Derby. Reports indicate the local chain will take over the space at 317 N. Rock
She voted for Trump every time. Then came cancer and the bills
Cindy Banda faces mounting medical bills after battling breast cancer. Despite the single mother's positive outlook, the financial strain combined with the high cost of living is overwhelming. And it's
Political analysis favors Mendoza over Ciscomani
The Cook Political Report has switched its assessment of the congressional race for the House seat from a “toss-up” ranking to “Leans Democratic.”
Business Ins and Outs | Atlanta dessert shop, Provisions, Mexirican and donut shop opening
Business Ins and Outs | Atlanta dessert shop, Provisions, Mexirican and donut shop opening
What analysts are watching in the Texas Senate race, CBS News political experts weigh in
CBS News political experts weigh in on Texas Senate race halfway through early voting
The latest CBS News poll showed Talarico leading 51% to 49%, well within the margin for error.
Skeleton Festival returns with ghosts, superheroes and family fun
Downtown Harrisonburg was covered with fantasy creatures like dragons, superheroes and princesses Saturday afternoon during the annual Skeleton Festival.
Review: 'Whalefall' a big fish tale thriller within a fraught father/son relationship
Movie reviewer Joshua Hill says 'Whalefall' combines a fraught father/son relationship with a suspenseful narrative featuring excellent sound design and imagery.
AP Exclusive: Trump’s border chief defends wall plans in Texas’ Big Bend despite a court setback
The Trump administration's top border official is defending plans to build a wall in Texas' Big Bend region. Customs and Border Protection Commissioner Rodney Scott argues the entire $46 billion
What Californians should know about Prop. 42
The measure could block the billionaire tax — and more.
AP Exclusive: Trump’s border chief defends wall plans in Texas’ Big Bend despite a court setback
The Trump administration's top border official is defending plans to build a wall in Texas' Big Bend region. Customs and Border Protection Commissioner Rodney Scott argues the entire $46 billion
Best AI Tools for Small Business Marketing (2026): CapCut Featured for Creating Professional Video and Visual Content by Expert Consumers
Expert Consumers has recognized CapCut in its 2026 coverage of the best AI tools for small business marketing, highlighting the platform's collection of AI-powered features for creating and editing video, images, audio, and other visual content. The recognition reflects growing interest in tools that support practical marketing activities, including campaign development, promotional content production, and adapting creative assets for different digital channels.
Madison Ballet makes 'Jekyll & Hyde' a psychological thriller
The ballet's world premiere of 'Jekyll & Hyde' runs Oct. 30-Nov. 1 in the Starlight Theatre at MYArts, with more dancing than grisly murder.
Why partisan politics may be changing people's accents
With the midterms fast approaching, communicating just the right message has been top of mind on all sides of the political aisle
Gov. Meyer announces the inclusion of the Verizon BEAD Project
Governor Matt Meyer announced the addition of the Verizon Broadband Equity, Access, and Deployment (BEAD) project to the JobsFirst Accelerator program.
Meet the New Orleans Halloween fanatics sparing no expense to delight or fright, ‘just because’
Come October, these otherwise average homes transform. Spiderwebs shroud the shrubbery. Candles flicker in the windows. Ghosts and ghouls haunt the front porch. These aren’t the kind of households to give out “chump candy.”
Union to Dedicate Historic Marker Commemorating Battle of Connecticut Farms as Part of America's 250th Celebrations
Union – The Township of Union Planning Committee for the 250th Anniversary of the United States, in partnership with the Union Township Historical Society, invites residents and history enthusiasts...
VT Science Corner: Expanding eating disorder care to rural areas
The great Taylor Swift proclaimed “I’m the problem, it’s me” in her 2022 song, "Anti-Hero." This lyric reflects something many people can recognize: the belief that something is fundamentally wrong
Inside a California shopping center's struggle to reinvent mall food
LOS ANGELES — Westfield Topanga is one of Southern California's most popular malls, but it has grappled with what to do with the empty space left when it lost its
Tri-state people in business: New hires, promotions, recognitions
Medical Associates Clinic of Dubuque announced the following new hires:
Politics: Trump's prioritization of Iowa not unusual
The big news in Dubuque late last week was that President Donald Trump will hold a rally here just two days before Election Day.
‘Friday the 13th’: Grading the 12 films
Winding up on the floor of a movie theater is never a good thing. But that’s where one frightened audience member wound up in 1980 after seeing “Friday the 13th”
Science Hill lost in the TSSAA state volleyball finals on Friday
Franklin's win capped a banner day for Nashville-area Division I programs as they teams swept the Class A (Eagleville), AA (Valor Prep) and AAA championships.
More than barbecue: Lexington festival brings big business and a community together after devastating fire
DAVE RAMSEY: Will the dream (car) become reality?
This week’s installment of down-to-earth personal finance advice from Dave Ramsey and the Dave Says column.
Science and Sense: The big election column
Although Science and Sense tries to avoid politics, we have an important election soon, and this is, after all, an Opinion column. It might be argued that “Political Science” is
Alabama Renaissance Faire celebrates its 40th year
FLORENCE — Alabama’s Renaissance Faire is celebrating its 40th year this weekend at “The Fountain on the Green,” which is also known as Wilson Park. The event features costumed performers
Bell County early voting reaches 42,964 ballots through Saturday
Bell County voters cast 7,523 ballots on Saturday, Oct. 24, pushing the cumulative early voting turnout to 42,964 through the first six days of voting.
Colorado high school students get a head start on healthcare careers
Sunday Preview – Orlocks rule the roads of Necromunda
See what’s coming up next week for Necromunda, Warhammer 40,000, and more.
Golden Demon 2026 winners revealed at SPIEL Essen
All of the miniatures that took home a trophy at Warhammer’s ultimate painting competition.
FEMA deadline approaching for NW Indiana residents, businesses impacted by Aug. 11 storms
Is the WA ‘millionaires tax’ really coming for public pensions?
SEATTLE — When you think about the mansion- and yacht-owning millionaire crowd, retired schoolteachers don't typically leap to mind. Nevertheless, foes of Washington's new high-earner income tax are making a
Meet the volunteers helping adults navigate their health
Bell County Indigent Health director answers questions about hospital district on ballot
As early voting continues in Bell County, a lot of voters headed to the polls are wondering about a proposition on the ballot calling for a new hospital district in
Small businesses struggling with inflation amid Trump tariffs ahead of midterms
Obama, in Ohio, assails 'cruelty' from Trump in campaign
Former President Barack Obama has stepped into one of America's ugliest midterm fights as he works to rally Democratic voters in battleground Ohio.
Trump casts his midterm ballot early in Florida
President Donald Trump has cast his ballot in the midterm elections, voting for all Republicans in Florida before speaking at a Georgia rally. Trump and first lady Melania Trump arrived
OPED-YOUTH-MENTAL-HEALTH-COMMENTARY-FILEPIC-DMT
In their daily lives, young people are navigating ever-evolving digital spaces that have not been designed with their needs at the forefront.
Oakland County business accused of making false statements to obtain federal loan agrees to $1M+ settlement
A Wixom, Michigan, business accused of making false statements to obtain a loan it was ineligible for has agreed to pay a settlement of just over $1.5 million after it was sued by the federal government, according to the Department of Justice.
Swing House districts are disappearing as gerrymandering grows
The number of politically competitive U.S. House seats is shrinking rapidly.
Celebrate Halloween with Jervis Library in Rome
Jervis Public Library in Rome has announced its upcoming events for the final week in October, including being open for trick-or-treating for a book on Halloween.
OU-Mississippi State football: Live updates, TV details
OU is set to kick off against Mississippi State at 2:30 p.m. at Davis Wade Stadium in Starkville on SEC Network.
OU honoring Sean Hutton against Mississippi State
The Sooners are honoring hospitalized player Sean Hutton with helmet stickers against Mississippi State.
Dodgers Questions Resurface With Mark Walter Reportedly Seeking Sparks Sale
Dodgers owner Mark Walter is still selling his sports assets and is reportedly shopping the Los Angeles Sparks.
Proposed Downtown Lodi cocktail bar faces broader police concerns
A new cocktail bar could be coming to Downtown Lodi, bringing another option for people looking to grab a drink. But as city planners weigh the proposal, police have raised
UD's business school gets new name, home in 2027
The University of Dubuque has announced an extraordinary investment in the future of business education.
Inside Texas Politics | Full Interview with Dallas Police Association President Sean Pease
France’s latest debt warning describes a country where governance is breaking down — and even doing too little, too late is barely possible
"The negative outlook reflects the increased risk that the fragmentation of France's political landscape will continue to impair the functioning of the country's legislative institutions."
What is it like being a business neighbor to Foy’s Halloween Store? Here’s what some of them said
Editor’s note: This article originally published in October 2025.
Health Department releases food inspection reports for week of Oct. 11
Find out how your favorite restaurant, convenience store and other food establishments in Jefferson County are performing on Health Department inspections.
Ohio policymakers wrestle with prediction markets as wagers on sports and politics explode
Attorney: Murder suspect will use mental health defense
An attorney for a Nogales man accused of killing his brother in March said his client’s mental health at the time of the shooting will play into the case.
I've got egg on my face because Steam's Personal Calendar feature has apparently been a test this whole time and is only now actually a fully fledged component
Look, I've had a lot going on, alright?
Celtics Hold Valuable Draft Assets Ahead of Important Weekend Decision
The Boston Celtics' G League affiliate, Maine, holds three picks in the 2026 NBA G League Draft, offering a chance to add young talent. The post Celtics Hold Valuable Draft Assets Ahead of Important Weekend Decision appeared first on HEAVY.
Connie Britton's New Hulu Thriller 'Phony': Finally a Mystery We Won't Solve Right Away
There are a lot of great TV shows out right now. One of them happens to be the new Hulu show everyone is talking about 'Phony' starring Connie Britton and Sam Nivola. Here, my honest review of 'Phony' on Hulu.
These clever apps show off the iPhone Duo's potential
From retro cassette players and virtual notebooks to flight trackers and even a digital toaster, developers are finding creative ways to take advantage of Apple's first foldable iPhone.
This US House district was once a political battleground. Now it shows why Congress is dysfunctional
The number of politically competitive U.S. House seats is shrinking rapidly. There are many reasons. People have stopped splitting their tickets when voting and now usually support one party in
Dear Abby | Disliked dad's daughter receives no condolences
Dear Abby: A friend's wife's elderly biological father was killed in a one-car auto accident recently. She had been estranged from him for as long as I can remember (more
Overnight business fire in Girard under investigation
GIRARD - Multiple departments responded to a business fire early Saturday in Girard.
AOC can draw a crowd. The midterms will test whether her politics can win before 2028
Alexandria Ocasio-Cortez is drawing big crowds as she campaigns for progressive Democrats before the Nov. 3 election. Supporters have packed rooms and chanted her name during appearances that have taken
AOC tests her progressive message. The results could help shape her future
Alexandria Ocasio-Cortez is drawing big crowds as she campaigns for progressive Democrats before the Nov. 3 election.
AOC can draw a crowd. The midterms will test whether her politics can win before 2028
WASHINGTON (AP) — Alexandria Ocasio-Cortez has had little trouble drawing a crowd.
Stephen King's ‘Carrie’ Just Got Renewed for Season 2
Prime Video's chilling adaptation of Stephen King's 'Carrie' is officially getting another season. Here’s what we know about the renewal.
Xbox's first chief operating officer Helen Chiang leaves Microsoft just three months into the job
Helen Chiang is leaving Microsoft just three months after becoming Xbox's first chief operating officer, according to a memo from CEO Asha Sharma.