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Results for " grade " 2,299 found 🔀 AI-powered Shuffle

Galaxy S27 Pro and S27 Ultra to get major display upgrade

Samsung’s Galaxy S27 Pro and S27 Ultra are reportedly set to receive M16 OLED panels, promising improved brightness, color accuracy, efficiency, durability and new privacy features. The standard S27 models, however, are expected to use older M14 technology.

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Sep 13 • 12:15 PM EDT • Technology • notebookcheck.net
Apple’s iPhone 18 Pro vs. 14 Pro: The Four-Year Difference Between Apple’s Pro Phones

If you're considering an upgrade from the iPhone 14 Pro to the iPhone 18 Pro, you'll see a lot of improvements.

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Sep 13 • 11:40 AM EDT • Technology • cnet.com
Xbox Series X and S Update Brings New Upgrades to the Consoles

A new Xbox Series X and Xbox Series S update has added new upgrades and features to the pair of Microsoft consoles.

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Sep 13 • 11:06 AM EDT • Technology • comicbook.com
A Galaxy S27 Ultra upgrade to match the iPhone Duo

Samsung isn't cutting corners everywhere.

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Sep 13 • 10:20 AM EDT • Technology • phonearena.com
Qualys Stock Drops After Wedbush Downgrades Core Cybersecurity Business

Qualys stock fell 7% after Wedbush downgraded the cybersecurity firm to Neutral, despite Qualys beating Q2 earnings and revenue estimates.

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Sep 13 • 8:07 AM EDT • Business • tikr.com
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Colts Make Roster Tweaks Ahead of Ravens Matchup

The Indianapolis Colts downgraded one injured player and elevated one from the practice squad.

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Sep 13 • 5:17 AM EDT • Sports • sports.yahoo.com
Galaxy S27 Pro and S27 Ultra to get biggest OLED upgrade in 3 years

Samsung is making big changes to the Galaxy S series next year. The company is expected to launch four Galaxy S27 series phones early in the year, and two of th

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Sep 13 • 3:40 AM EDT • Technology • sammobile.com
How we grade Auburn football against Southern Miss: Report card

How did Auburn football fare against Southern Miss? Here's our grades for offense, defense and special teams, as well as our MVP.

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Sep 13 • 12:22 AM EDT • Sports • sports.yahoo.com
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Kene Nwangwu to miss opener

Jets RB Kene Nwangwu downgraded from doubtful to out for Week 1

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Sep 12 • 3:06 PM EDT • Sports • sports.yahoo.com
F1 Spanish Grand Prix: Every Team’s Reported Madrid Upgrade Package

Here are the reported upgrades that each F1 team will bring to Madrid.

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Sep 12 • 10:00 AM EDT • Sports • sports.yahoo.com
Apple iOS 27 Release Date Is Sept. 14: Check If Your iPhone Can Upgrade

Can your iPhone run the latest iPhone software when it arrives in a matter of days? Here’s a complete list of compatible hardware and what’s in the release.

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Sep 12 • 6:00 AM EDT • Technology • forbes.com
Charles County Grant Supports Outdoor STEM Education

A $15,566 grant will help the Alice Ferguson Foundation provide outdoor STEM education for Charles County third graders and teachers.

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Sep 12 • 6:00 AM EDT • Science • thebaynet.com
Liverpool schedule talks with 'very strong' star in 2027

Liverpool may have made four signings in the summer but, there are still a lot of areas among their ranks that could do with an upgrade or two.Indeed, Andoni Iraola's defence and attack have been mass...

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Sep 12 • 4:10 AM EDT • Sports • sports.yahoo.com
iPhone 18 Pro vs iPhone 15 Pro: Three-year upgrade

The average timetable between pro iPhone upgrades is three years. Apple's iPhone 18 Pro has arrived, with iPhone 15 Pro owners taking a close look. Here's how the two compare.

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Sep 11 • 1:55 PM EDT • Technology • appleinsider.com
Vermont has begun doling out federal rural health funding

State and federal officials announced $11.7 million in funding that will go toward a scholarship program for healthcare workers and upgrades at three nursing homes.

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Sep 11 • 1:16 PM EDT • Health • vermontpublic.org
New traffic rules and food upgrades at The Vaught

OXFORD, Miss. (WJTV) – Ole Miss Athletics announced new adjustments and enhancements to The Grove and Vaught-Hemingway Stadium ahead of the football team’s first home game of 2026 on September 12, 2026. New Grove Traffic Flow With construction ongoing at Jones Hall, portions of Grove Loop will be closed to thru traffic on gamedays. Vehicles […]

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Sep 11 • 11:49 AM EDT • Sports • sports.yahoo.com
Blackstone (BX) Eyes $2 Billion ZO Skin Health Exit

Blackstone Inc. (NYSE:BX) is exploring a possible sale of ZO Skin Health, the medical-grade skincare company founded by dermatologist Dr. Zein Obagi. Reuters reported that the business could be valued at around $2 billion. The process is still in the early stages, and Blackstone is working with Citigroup and Raymond James on the potential sale. […]

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Sep 11 • 11:37 AM EDT • Health • finance.yahoo.com
Siri AI is coming: Here are three times it’s really impressed me so far

Siri AI launches next week in iOS 27, and it’s a huge upgrade. Here are three examples of times the new Siri has impressed me so far.

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Sep 11 • 11:31 AM EDT • Technology • 9to5mac.com
S&P downgrades Lucky Strike Entertainment rating on weak margins

S&P downgrades Lucky Strike Entertainment rating on weak margins

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Sep 11 • 10:54 AM EDT • Entertainment • investing.com
Elly De La Cruz is acing the 2026 MLB season

You’ve graded his season so far, and he’s passing all the tests.

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Sep 11 • 10:43 AM EDT • Sports • sports.yahoo.com
Apple Watch Ultra 4 vs Ultra 3: Here’s everything new

Apple Watch Ultra 4 might look just like Ultra 3, but it packs big internal upgrades. Here’s everything new in Apple Watch Ultra 4 vs 3.

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Sep 11 • 10:22 AM EDT • Technology • 9to5mac.com
What Upgrading to iPhone 18 Pro From iPhone 17 Pro Gets You

Apple's new iPhone 18 Pro and iPhone 18 Pro Max largely build on last year's models with a series of targeted upgrades rather than a major redesign. The most notable changes dial in better performance, camera capabilities, battery life, and wired charging speeds. Several key specifications remain unchanged from the iPhone 17 Pro models.

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Sep 11 • 8:43 AM EDT • Technology • macrumors.com
Zay Flowers upgraded on Ravens’ Week 1 injury report

The Ravens’ star wide receiver should be good to go for Baltimore’s Week 1 against the Indianapolis Colts.

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Sep 11 • 7:00 AM EDT • Sports • sports.yahoo.com
Just across the Hudson, the Western Hemisphere’s largest planetarium is getting a massive $40M upgrade—adding a 90-foot upside-down balloon, river otters, and a touching 9/11 Memorial Garden

Liberty Science Center's massive $40M expansion brings a 90-foot upside-down balloon, a touching 9/11 Memorial Garden, and epic planetarium upgrades.

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Sep 11 • 6:40 AM EDT • Science • secretnyc.co
How Flex Pay Launch At Six Flags Entertainment (FUN) Has Changed Its Investment Story

Six Flags Entertainment introduced Flex Pay by Upgrade in September 2026, letting eligible guests buy Season Passes and other products of US$49 or more online and pay over time through fixed monthly installments, with immediate access to pass benefits after activation and no prepayment penalties. This financing option could influence how visitors budget for trips, with more spending potentially shifting toward recurring passes and planned visits rather than one off ticket purchases. This...

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Sep 11 • 6:21 AM EDT • Entertainment • simplywall.st
Dartmouth Health Children’s hospital receives $30M gift, new name

A $30 million dollar gift to Dartmouth Health Children’s hospital from entrepreneur Tom Golisano is giving the facility an upgrade and a new name.

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Sep 10 • 6:10 PM EDT • Health • wcax.com
Apple iPhone 18 Pro Max vs. Samsung Galaxy S26 Ultra: The Highest-End Phones Compared

The iPhone 18 Pro Max has a big camera upgrade -- and a bigger price. How does it compare to Samsung’s flagship phone?

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Sep 10 • 5:45 PM EDT • Technology • cnet.com
From learning to doing: How Davidson County Schools is putting the science of reading into practice

Davidson County Schools helped third grade teachers turn science of reading knowledge into daily practice by creating teacher-led units.

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Sep 10 • 5:30 PM EDT • Science • ednc.org
Maryland teachers now have new interactive science tool from state Ag officials

Explore Chesapeake Bay watershed education with engaging lessons designed for students in grades three to eight.

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Sep 10 • 3:08 PM EDT • Science • localnews1.org
Upgrading to Apple Watch Series 12 Could Cost You Hypertension Notifications

Some Apple Watch users who upgrade to the Series 12 or the Ultra 4 might temporarily lose access to hypertension notifications. On the watchOS feature availability page, Apple says notifications might not be available on the Series 12 or Ultra 4 at launch because regulatory clearances are in process. Hypertension Notifications may not be available on Apple Watch Series 12 or Ultra 4 in your region, as additional regulatory clearances for these devices are in process.

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Sep 10 • 2:57 PM EDT • Technology • macrumors.com
Sanford MedX returns for Bemidji area high school students

BEMIDJI, Minn. – Sanford Health’s MedX career exploration program will return for the 2026–2027 school year, offering middle and high school students in grades 7–12 a hands-on look into the world of health care. The free program kicks off with four fall sessions starting Sept. 22, held from 6 to 7:30 p.m. at Sanford Bemidji […]

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Sep 10 • 2:08 PM EDT • Health • news.sanfordhealth.org
Apple Watch Ultra 4 Hands-On: A Closer Look at Its Biggest Upgrades

Finally a battery worthy of an ultra marathon, better health sensors and a powerful processor that keeps it running.

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Sep 10 • 1:19 PM EDT • Technology • cnet.com
University of Iowa Health Care calls off $2B+ patient tower build

Plans to build a new, $2 billion-plus patient care tower and other accompanying upgrades at the University of Iowa Health Care’s main campus are off the table in favor of smaller-scale upgrades to | "Significant financial challenges” facing the healthcare industry at large have limited Iowa Health Care’s ability to “responsibly” deploy capital toward the five-year build. It is now proposing a $380 million capital plan focused on updating and expanding existing facilities.

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Sep 10 • 12:00 PM EDT • Health • fiercehealthcare.com
Sony introduces the WH-1000XM4C, its new wireless noise-cancelling headphones inspired by its most popular over-ear model

Your headphones game just got an upgrade with Sony’s brand new WH-1000XM4C, which builds on its popular WH-1000XM4; combining the legendary 1000X Series noise cancellation, trusted premium sound in its beloved timeless design. Image courtesy of Sony. Ideal for everyone from the frequent travellers to students and commuters, the WH-1000XM4C is able to deliver rich […]

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Sep 10 • 11:53 AM EDT • Technology • nylon.com.sg
Avianca Unveils Upgraded INSIGNIA Business Class

For Avianca delivering a high-quality experience to its customers is a strategic priority that is reflected in its continued investment in its product,

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Sep 10 • 11:03 AM EDT • Business • metroairportnews.com
Bloomsburg Children’s Museum now accepting registrations for annual science fair

Students in grades 6-12 can now register for the Bloomsburg Children’s Museum’s 12th Annual Science Fair, which will be held in January.

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Sep 10 • 11:00 AM EDT • Science • northcentralpa.com
Skyline Chili names new CEO, a P&G vet, amid more than $20M in investments

Carl Stealey takes over as CEO of the Cincinnati-based chili chain after Dick Williams invested over $20 million in upgrades.

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Sep 10 • 10:58 AM EDT • Business • bizjournals.com
Dartmouth Health Children’s hospital receives $30 million gift and a new name

A $30 million dollar gift to Dartmouth Health Children’s hospital from entrepreneur Tom Golisano is giving the facility an upgrade and a new name.

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Sep 10 • 10:34 AM EDT • Health • wcax.com
Apple Watch Ultra 4 and Series 12 have surprise upgrade that wasn’t announced

Apple Watch Series 12 and Apple Watch Ultra 4 are here, and new findings reveal they each have a surprise upgrade not mentioned by Apple.

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Sep 10 • 9:54 AM EDT • Technology • 9to5mac.com
iPhone 17 Pro vs. iPhone 18 Pro: 35+ Upgrades Compared

Apple yesterday announced the iPhone 18 Pro and iPhone 18 Pro Max, succeeding the iPhone 17 Pro that launched last September. The new models are built around the A20 Pro chip, a 48-megapixel Fusion Main camera with variable aperture, a redesigned vapor chamber, and a smaller Dynamic Island. Last year's iPhone 17 Pro brought one of the biggest design changes to the lineup in years, switching from a titanium frame and glass back to an aluminum unibody with Ceramic Shield 2.

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Sep 10 • 9:18 AM EDT • Technology • macrumors.com
Insta360 Luna Pro review: Your Instagram Reels are about to get an upgrade

There’s now a direct rival to the Osmo Pocket 4 you can easily buy in the US.

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Sep 10 • 9:00 AM EDT • Technology • engadget.com
Scientists want to 3D print houses on Mars with the help of yeast

Mars is a terrible place to build a house. It’s bitterly cold, blasted by radiation, and a near vacuum. Not to mention that the building materials, even for a modest shelter, could spend months hurtling through space before construction begins. But they don’t have to. In a study publishing September 10 in the journal Chem Circularity, researchers developed a recipe that could one day be used to 3D print houses on Mars. The recipe combines Martian rocks with Earthly ingredients: gelatin and yeast. Once dried and hardened, this living building material is as strong as low-grade concrete and can be broken down, recycled, and brewed again for new construction.

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Sep 10 • 8:00 AM EDT • Science • eurekalert.org
A.J. Brown downgraded to out with ankle injury

The Patriots will not have their star receiver for the rest of Wednesday's season opener against the Seahawks.

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Sep 9 • 10:43 PM EDT • Sports • sports.yahoo.com
Is Six Flags Entertainment (FUN) A Bargain On Its New Flex Pay Launch?

Six Flags Entertainment (FUN) just rolled out Flex Pay by Upgrade, a buy now pay later style option for online purchases from $49, including Season Passes and other qualifying products. For investors watching Six Flags Entertainment, the latest product moves are coming against a tougher backdrop, with the share price down 41.4% over the past 90 days and the 1 year total shareholder return declining 34.0%. This points to fading momentum and a market that is pricing in higher risk, even as...

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Sep 9 • 10:19 PM EDT • Entertainment • simplywall.st
Can Orlando Magic Exceed Shockingly Low Expectations

Reeling from a playoff collapse and a dismal D+ offseason grade, Orlando bets on rookie coach Sean Sweeney and a veteran reunion to spark their stagnant offense.

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Sep 9 • 10:10 PM EDT • Sports • sports.yahoo.com
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Parma elementary student wins Super Bowl tickets after completing a heart health challenge

A Parma City Schools first-grader walked into what she thought was a school assembly and walked out with tickets to the Super Bowl.

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Sep 9 • 6:59 PM EDT • Health • news5cleveland.com
Gainesville delays business tax renewal notices during software upgrade

New software expected to launch in January 2027.

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Sep 9 • 4:30 PM EDT • Business • mainstreetdailynews.com
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Apple unveils Watch Series 12 and Watch Ultra 4 with an AI upgrade that can recap your day

Most notably, Apple is taking aim at the growing wave of AI wearables with new "Audio Intelligence" features that let you rewind moments and remember details from daily conversations.

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Sep 9 • 2:08 PM EDT • Technology • techcrunch.com
Apple Watch Ultra 4 Comes With Better Battery And Upgraded Health Tracking

The Watch Ultra 4 isn't a major redesign, but does come with some notable improvements.

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Sep 9 • 2:02 PM EDT • Health • engadget.com
watchOS 27 upgrade coming to Apple Watch this month

watchOS 27 is coming this month, and now we have an official release date. Apple says we can expect the...

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Sep 9 • 1:57 PM EDT • Technology • 9to5mac.com
Apple Announces Apple Watch Series 12 With S11 Chip, Upgraded Health Sensors and Ceramic Models

Apple today announced the Apple Watch Ultra 4, featuring a new S11 chip, a redesigned health sensing system, and a larger battery that Apple says delivers two days of battery life. With improved power efficiency, Ultra 4 offers up to 18 hours of workout tracking with full GPS and heart rate monitoring, or 45 hours in its maximum extended workout mode. It comes in Black and Natural titanium, alongside new band colors and a new titanium Hermès band.

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Sep 9 • 1:42 PM EDT • Health • macrumors.com
Apple announces A20 Pro chip with 2nm design and major performance gains

Apple today unveiled the A20 Pro, its first chip built on 2nm technology at its “Surprise and Shine” event, bringing major CPU, GPU, and AI upgrades to the iPhone 18 Pro lineup.

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Sep 9 • 1:37 PM EDT • Technology • 9to5mac.com
Apple unveils AirPods 5 with upgraded noise cancellation, more

Today during its iPhone 18 Pro event, Apple announced the next generation AirPods 5 with improved active noise cancellation.

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Sep 9 • 1:34 PM EDT • Technology • 9to5mac.com
Apple launches iPhone 18 Pro with upgraded camera

Apple's new iPhone 18 Pro lineup upgrades the camera and comes in burgundy.

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Sep 9 • 1:26 PM EDT • Technology • techcrunch.com
East El Paso bakery receives near-failing health inspection score: List

See which El Paso restaurants earned perfect scores and which ones received a C grade in the latest health inspections.

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Sep 9 • 10:12 AM EDT • Health • elpasotimes.com
Apple Shares Mysterious Teaser Video Before 'iPhone Duo' Event Today

Apple will be holding an event today starting at 10 a.m. Pacific Time, with the company expected to unveil new iPhones and much more. Ahead of the event, Apple's new CEO John Ternus just shared a mysterious teaser video. The short clip appears to show a beam of light that is shining onto the edge of an iPhone. The light is coming from a hexagonal shape that changes size, which could hint at the iPhone 18 Pro's rumored mechanical aperture upgrade.

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Sep 9 • 9:54 AM EDT • Technology • macrumors.com
Apple reportedly offering trade-in incentive to encourage iPhone upgrades

We’re expecting today’s shiny new iPhones to be accompanied by price raises, even if they aren’t as painful as initially...

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Sep 9 • 9:09 AM EDT • Technology • 9to5mac.com
Sphere Entertainment (SPHR) Expands 4D Wizard Of Oz As Valuation Hinges On Growth Story

New 4D effects spotlight Sphere Entertainment’s product ambitions Sphere Entertainment (SPHR) just rolled out an expanded 4D package for The Wizard of Oz at Sphere, adding animatronic Winged Monkeys, themed scents, Glinda Glitter, pyrotechnic fireworks, and scented apples from September 25, 2026. For investors watching Sphere Entertainment, the latest 4D upgrade lands after a choppy few months, with the share price down about 11% over 30 days but still showing strong momentum through a 51%...

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Sep 9 • 3:21 AM EDT • Entertainment • simplywall.st
Grading Baker Mayfield's Extension with the Buccaneers

Tampa Bay and Baker Mayfield finally agreed to a contract extension that keeps the franchise QB with the team through 2029. What grade does the new deal deserve?

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Sep 8 • 11:44 PM EDT • Sports • sports.yahoo.com
Let’s Grade That Win Over Coastal Carolina by Position Group

Hope everybody enjoyed the holiday the right way. Grill going, family around, maybe a cold drink in your hand, and a win in the books to talk about while you do it. That’s the good life. Before we get too deep into the cookout, let’s talk about what we saw Saturday, because there’s a lot […]

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Sep 8 • 6:37 PM EDT • Sports • sports.yahoo.com
Blackstone explores sale of ZO Skin Health, sources say

Investment firm Blackstone is looking to sell ​medical-grade skincare company ZO Skin ‌Health, which could be valued at around $2 billion in any deal, according to ​people familiar with the matter.

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Sep 8 • 5:19 PM EDT • Health • reuters.com
UCF Graded Top-10 Performer in CFB Following Week One

After a 73-6 blowout fueled by Duke Watson’s explosive debut, the Knights carry elite Pro Football Focus grades into a high-stakes road test against Pittsburgh’s high-powered offense.

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Sep 8 • 3:57 PM EDT • Sports • sports.yahoo.com
We redshirted our son for kindergarten. Then he skipped a grade.

We held our son back for kindergarten because of different state cutoffs. When he became bored academically, we moved him ahead a grade.

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Sep 8 • 3:50 PM EDT • Business • businessinsider.com
Sonos just launched ‘Sonos 27’ app update, here’s what’s new

Last week Sonos unveiled several new features coming soon, and now the first of those upgrades are here in the ‘Sonos 27’ app update.

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Sep 8 • 2:59 PM EDT • Technology • 9to5mac.com
OpenAI releases ChatGPT Images 2.5 with 'sharper details' and 'more precise editing'

In April, OpenAI released upgraded image generation technology with ChatGPT Images 2. Five months later, the company is releasing an...

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Sep 8 • 2:50 PM EDT • Technology • 9to5mac.com
Kansas Football Earns Third-Best Team Performance Grade From PFF

Kansas Football Earns Third-Best Team Performance Grade From PFF

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Sep 8 • 1:09 PM EDT • Sports • sports.yahoo.com
Honda Postpones Big Upgrades to 2027

The Japanese brand's trackside boss confirms no significant evolution this year. The AMR26's lack of top speed showed at Monza, with Alonso and Stroll posting the weekend's worst times.

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Sep 8 • 1:00 PM EDT • Sports • sports.yahoo.com
How did CBS Sports grade the Oklahoma Sooners for Week 1 win?

CBS Sports awarded Oklahoma an A- for its dominant win over UTEP in the season opener.

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Sep 8 • 12:00 PM EDT • Sports • sports.yahoo.com
Apple Cinemas announces multimillion-dollar overhaul of Providence theater

Apple Cinemas announced plans for a multimillion-dollar transformation of its Providence location, including upgraded auditoriums, and bowling.

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Sep 8 • 10:58 AM EDT • Entertainment • turnto10.com
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD

With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.

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Sep 8 • 10:50 AM EDT • Science • fiercebiotech.com
Sulphur Springs ISD Announces Annual Science Fair for Grades 4–5

SULPHUR SPRINGS, TX — Sulphur Springs Independent School District (SSISD) has officially announced its 2026–2027 Science Fair, inviting young minds in

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Sep 8 • 10:00 AM EDT • Science • ksstradio.com
SteelSeries’ pro-grade, wireless Xbox controller sure is expensive

Two hundred and fifty nine dollars.

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Sep 8 • 10:00 AM EDT • Technology • theverge.com
Instant grades for Christian Gonzalez contract extension with Patriots

The Patriots are keeping their top cornerback on a new four-year extension.

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Sep 8 • 7:05 AM EDT • Sports • sports.yahoo.com
California later school start times boost grades, sleep, study says

California middle and high school students report better mental health and grades with later start times, study finds.

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Sep 8 • 6:00 AM EDT • Health • latimes.com
PS5 ‘major system upgrade’ on the way with hefty graphics boost

It's the biggest update to drop on PlayStation 5 in a while.

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Sep 8 • 5:33 AM EDT • Technology • gamingbible.com
Canon EOS R8 Mark II Leak: Specs, IBIS Upgrades, and Design Revealed Ahead of Launch

Leaked Canon EOS R8 Mark II details reveal a redesigned angular body, 7.5-stop IBIS, joystick, and €1,879 price point ahead of its September 15 release.

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Sep 8 • 3:29 AM EDT • Technology • canonrumors.com
Contract grade for Christian Gonzalez's $135 million extension with Patriots

It’s about time . One of the many stories around the New England Patriots this offseason was their contract negotiations with star cornerback Christian Gonzalez. Gonzalez firmly entrenched himself as one of the best cornerbacks in the league last season. With the 2026 season being his fourth season in the league, Gonzalez was due for a contract […] The post Contract grade for Christian Gonzalez's $135 million extension with Patriots appeared first on ClutchPoints.

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Sep 8 • 2:19 AM EDT • Sports • sports.yahoo.com
Justin Jefferson Gets Blunt Prediction Before Vikings-Packers Game

The 2025 NFL season was a challenging one for Minnesota Vikings wideout Justin Jefferson. Due to the quarterback play, Jefferson barely recorded over 1,000 receiving yards. The Vikings star recorded an 80.5 PFF grade along with 84 receptions on 140 targets, 1048 receiving yards, and one touchdown.Moreover, Jefferson registered 12.5 yards per reception, 5.2 yards […] The post Justin Jefferson Gets Blunt Prediction Before Vikings-Packers Game appeared first on HEAVY.

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Sep 7 • 10:37 PM EDT • Sports • sports.yahoo.com
Japan upgrades Q2 GDP on slight capex improvement

By Satoshi Sugiyama TOKYO, Sept 8 (Reuters) - Japan's economy grew faster than initially estimated in the April-June quarter from the previous three months, supported by business spending that was

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Sep 7 • 8:20 PM EDT • Business • lufkindailynews.com
Patriots rule one player out for Wednesday's opener against Seahawks

Patriots swing offensive lineman Ben Brown has officially been downgraded as out for Wednesday's opener against the Seahawks.

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Sep 7 • 7:28 PM EDT • Sports • sports.yahoo.com
Six Flags Entertainment Corporation Introduces Flex Pay by Upgrade Allowing Guests to Purchase Season Passes and Qualifying Products Through Fixed Monthly Installments

Six Flags Entertainment Corporation introduced Flex Pay by Upgrade, a new payment option that allows eligible guests to purchase Season Passes and other qualifying products and pay over time through...

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Sep 7 • 12:05 PM EDT • Entertainment • marketscreener.com
iPhone 18 Pro: Nine Reasons Not to Upgrade This Year

Apple is set to unveil new iPhone 18 Pro and iPhone 18 Pro Max models on Wednesday, September 9, and the devices are expected to feature a design that's largely similar to the iPhone 17 Pro models, with a peppering of enhancements inside. Major changes are not expected until next year, when Apple is expected to introduce a radically redesigned 20th-anniversary iPhone.

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Sep 7 • 8:01 AM EDT • Technology • macrumors.com
Pro Football Focus details Texas A&M QB's successful 2026 debut

PFF provided Texas A&M QB Marcel Reed's day through the air on Saturday, detailing his deep throw grade and improved decision making when pressured.

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Sep 7 • 6:31 AM EDT • Sports • sports.yahoo.com
Most kids don’t know their rights. New book aims to fix that

Iowa City native and former public defender Emily Galvin Almanza has written “Andromeda Diaz and the Reasonable Doubt,” a middle-grade mystery to teach kids their constitutional rights and the power of due process.

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Sep 7 • 6:30 AM EDT • Entertainment • thegazette.com
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Lenovo's newest tablets come with Android 17, 7 OS upgrades, huge batteries, and stunning screens

The 11.1-inch Yoga Tab Gen 2 and 13-inch Yoga Tab Plus Gen 2 are without a doubt among the best Android tablets ever released by Lenovo, especially from a software standpoint.

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Sep 7 • 6:09 AM EDT • Technology • phonearena.com
Beyond grades: What parents expect from private schools

Changing times are reshaping parents’ expectations of private and independent schools. Parents look for much more than high grades and test scores.

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Sep 7 • 6:00 AM EDT • Business • chicagobusiness.com
Microsoft (MSFT)’s Outlook and OpenAI’s ChatGPT Work Both Broke the Same Day

On August 31, 2026, CNBC reported that Microsoft Corporation (NASDAQ:MSFT) suffered a widespread Outlook and Exchange Online outage on August 31, with Downdetector reports peaking at 6,015 for Outlook and 2,044 for Microsoft 365. Microsoft said on its status page that “users may experience degraded functionality with various Exchange Online functionalities” while it reviewed service […]

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Sep 6 • 8:29 PM EDT • Technology • finance.yahoo.com
Position Grades: Marshall

Might we have a Straight-A report card??

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Sep 6 • 1:55 PM EDT • Sports • sports.yahoo.com
See the Cowboys offseason grade according to fans

The Cowboys fanbase is pleased

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Sep 6 • 1:00 PM EDT • Sports • sports.yahoo.com
How to install Nvidia DLSS 5 on almost any RTX GPU in minutes

Your full guide to Nvidia's latest gaming upgrade.

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Sep 6 • 9:30 AM EDT • Technology • makeuseof.com
It’s Been Downloaded by Millions. It’s Supposed to Make You Happier. It Made Me Want to Strangle a Cartoon Bird.

A little bird told me there’s a way to meet my wellness goals. Then it asked me if I wanted to upgrade to their premium plan.

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Sep 6 • 9:24 AM EDT • Technology • slate.com
Duke 17, Tulane 3: Position grades for the Blue Devils

Handing out grades to each position following Duke's 17-3 victory over Tulane.

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Sep 6 • 8:01 AM EDT • Sports • sports.yahoo.com
Some DragonCon fans furious; Six kids living in deplorable conditions; Entertainment center's upgrade 97.5 Glory FM | North Georgia's Family Radio Station

(GA. NEWS NETWORK) *DragonCon is in Atlanta this weekend, but some fans are not happy. They booked at Stockbridge Suits nearly a year ago. But the hotel clo ...

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Sep 6 • 6:33 AM EDT • Entertainment • wgtjradio.com
Chargers Predicted to Upgrade Backup Quarterback Position Via Trade

If Justin Herbert gets hurt again and has to miss some time, the Chargers could be in trouble — unless they trade for a more reliable backup quarterback.

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Sep 6 • 12:20 AM EDT • Sports • sports.yahoo.com
China mines iron from tailings and low-grade ore to cut Australia, Brazil supply

Scientists have found a way to turn waste into a valuable resource on an industrial scale, reducing China’s dependence on iron ore imports.

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Sep 5 • 11:00 PM EDT • Science • scmp.com
New Super Smash Bros. Switch 2 game leaks before September Nintendo Direct

After revealing the Ocarina of Time remake and upcoming Nintendo Directs, the same leaker has offered another revelation. Rather than a Super Smash Bros. Ultimate Switch 2 upgrade, a game with unique characters may be in development. Even so, the platform fighter’s release date could be years away.

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Sep 5 • 9:17 PM EDT • Technology • notebookcheck.net
Seahawks Handed Strong A.J. Brown Warning Before Patriots Game

When the Seattle Seahawks open the 2026 NFL season against the New England Patriots, the reigning champions will face a player whom they didn’t see in their Super Bowl LX victory: A.J. Brown. Last season for the Philadelphia Eagles, Brown played 517 pass snaps, earning an 83.0 overall PFF grade. Moreover, the new Patriots receiver […] The post Seahawks Handed Strong A.J. Brown Warning Before Patriots Game appeared first on HEAVY.

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Sep 5 • 8:45 PM EDT • Sports • sports.yahoo.com
University of Michigan is hiding student grades — but effort to curb 'mental health crisis' is getting blowback
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Sep 5 • 8:18 PM EDT • Health • nypost.com
Nik McMillan Records Highest Individual Grade of Lance Leipold Era

Nik McMillan Records Highest Individual Grade of Lance Leipold Era

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Sep 5 • 7:38 PM EDT • Sports • sports.yahoo.com
PFF's highest-graded Patriots player in 2026 preseason revealed

Wide receiver Kyle Williams was recognized by Pro Football Focus as being the Patriots’ highest-graded preseason performer.

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Sep 5 • 11:00 AM EDT • Sports • sports.yahoo.com