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BV Chamber Hosts Business After Hours Tonight
Buena Vista Chamber of Commerce will host their Business After Hours event tonight from 5pm to 7pm at Strange Craft Beer Company at 324 East Main. The monthly e
Biggest moments of the 2026 Emmys, from Michael J. Fox to Taylor Swift
From surprise cameos and laugh-out-loud bits to heartfelt tributes, these are the moments everyone is talking about from the 2026 Emmy Awards.
Businesses can now apply for NIH funding
RFK Jr. to speak at Children's Health Defense conference, how to protect your heart in outer space, and more health news
Orioles news: O’s win in Alonso’s return to NYC
It was a heartwarming scene in New York last night.
New study warns nighttime light exposure may hurt heart health
Hackensack Meridian Medical Group's Dr. Craig Basman warns that too much light during nighttime sleep may damage the heart. He discusses the risks linked to nighttime light exposure and shares tips for better sleep.
Health for Hearts spreads word about importance of prevention
Having a healthy heart is key to brain health. Health for Hearts United is taking this message to Black churches during Alzheimer's Awareness Month.
Exercise — and echocardiograms — in space protected astronauts’ hearts in study
If humans journey to Mars in 2035, exercise will be critical to keeping their hearts strong in microgravity.
Hispanic Heritage Month: Representation matters for heart health
DALLAS, Sept. 15, 2026 — As Hispanic Heritage Month begins, a new report from the American Heart Association reveals a troubling milestone: cardiovascular disease has surpassed cancer as the leading cause of death among Hispanic adults in the United...
Performance Foodservice becomes first western Massachusetts Purple Heart business
Performance Foodservice in Springfield became the first company in western Massachusetts to be designated a Purple Heart Business.
Reading for pleasure: Lifelong health and cognitive benefits
Reading for pleasure—from tucking into a Jane Austen classic to devouring a Heartstopper graphic novel—is linked to better mental health, greater empathy and a lower risk of dementia, say researchers.
Common bedroom mistake could be quietly taking a toll on your health, experts say
A Tulane University study links sleeping with light on to higher risks of heart failure, atrial fibrillation, stroke and cardiovascular death.
Pre-Orders For The Android-Based Googlebook Laptops Open On September 21
Gemini Intelligence is at the heart of the operating system powering Google's upcoming laptops.
🚨XIs in: clash of contrasts between Villarreal and Betis
Estadio de la Cerámica bears witness to a clash shaped by opposite realities in LaLiga EA Sports. Iñigo Pérez’s Villarreal come into it reeling after a heartbreaking 2-3 defeat to Deportivo La Co...
Heart & Soul: Free clinic in Westfield offers health care to uninsured, underinsured
Hamilton County has a relatively low rate of people without health insurance. However, a free clinic in Westfield treated about 700 people – totaling approximately 1,700 patient visits – just last year. For Heart & Soul Free Clinic Executive Director Lisa Zouvelos Kreag, the
Scientists find a hidden cause of high blood pressure that routine tests can miss
A wearable device has revealed nighttime hormone surges that may expose a frequently missed cause of high blood pressure. The discovery could help explain why primary aldosteronism often escapes standard blood tests and point toward a more accurate way to diagnose it.
HOMETOWN HEALTH: Study finds heart disease risk can be identified in children as young as 8
A UT Health Houston study identified proteins that can influence the risk of developing cardiovascular-kidney-metabolic diseases in adulthood.
AFib is On the Rise: Dignity Health experts highlight warning signs
Atrial fibrillation — a quivering or irregular heartbeat (arrhythmia) — is a leading contributor to stroke, heart failure and other heart-related complications. The stakes are significant: medical research shows that
Should race affect BMI guidelines? Doctors are split
BMI is a quick, cheap way for doctors to estimate body fat and screen for conditions like heart disease and diabetes. But medicine has long known that BMI is problematic and unnuanced. By using it, groups of people have fallen through the cracks and conditions have been caught late. So, some doctors want to add nuance – to consider race when using BMI. But using race in medicine comes with its own problems. So what’s the way forward? To find out, we talk to Katie Wu, a science writer at The Atlantic.Read more of Katie’s reporting on BMI and race.Interested in more science health stories? Email us your question at shortwave@npr.org.Support public media with NPR+ and enjoy perks for over 25 podcasts like this one. This show’s perks include sponsor-free listening. Learn more at plus.npr.org.
Purdue 36 Wake Forest 38: Post Game Media Review
It was a heartbreaking way to lose a home game but even more so as Purdue looked to break a 21-game losing streak to Power 4 conference + Notre Dame opponents. Purdue rallied from being down 10 points late in the fourth quarter and had a chance to win but couldn’t l into the endzone […]
Zverev turns US Open tears into triumph
How a more composed Alexander Zverev stayed 'zen-like' to beat Ben Shelton and win the US Open, six years after a heart-breaking defeat in the final.
Alexander Zverev Defeats Ben Shelton to Become US Open Champion
For the second time this year, Alexander Zverev is a champion at the Major level, as six years after suffering a heartbreaking loss in the final of the US Open, he can now finally call himself a champion in New York. Entering the final as the firm favorite to win, the German, for once, didn’t …
Texans lose heartbreaker to Bills 36-31
It’s one game. It is really easy to overreact to the Texans’ performance on Sunday after losing a nailbiter. There was a lot to love about the game (the offense looked downright competent until the fourth quarter), there was a lot to hate (the secondary and Reed Blankenship in particular were hideous), and there was […]
What are statins? And can healthy people use them to prevent heart disease and dementia?
New evidence shows more people might benefit from this cholesterol-lowering medication than we previously thought. But that doesn’t mean everyone should take one.
Monument Health earns national recognition for heart and stroke care
Monument Health earns three national Get With The Guidelines achievement awards from the American Heart Association for outstanding heart and stroke care.
‘I Play Rocky’ Review: Expertly Weaponized Nostalgia Makes For Rousing, Light-Hearted Entertainment [TIFF]
Peter Farrelly’s ‘I Play Rocky’ turns Sylvester Stallone’s unlikely ‘Rocky’ origin story into broad, funny, expertly weaponized nostalgia.
What is the healthiest sport? The No. 1 pick, according to science
Playing tennis is associated with a 56% reduced risk of dying from heart disease compared to not playing the sport.
What is the healthiest sport? The No. 1 pick, according to science
Playing tennis is associated with a 56% reduced risk of dying from heart disease compared to not playing the sport.
🤝 René Higuita sends heartfelt message to James Rodríguez
James Rodríguez’s arrival at Atlético Nacional continues to draw major reactions in Colombian football. This time, the club’s legendary former goalkeeper and idol, René Higuita, dedicated an em...
Command the Old Gods in Reign of the Black Empire, Hearthstone's Next Expansion
Return to the age of the Black Empire, command the most powerful Old Gods Hearthstone has ever seen, and create custom minions with the new Assemble keyword.
Monument Health Rapid City Hospital earns ‘High Performing’ marks from U.S. News
Monument Health Rapid City Hospital is named High Performing by U.S. News & World Report for heart failure, stroke, kidney failure, and heart attack care.
Hearthstone To Get Its First New Class In Four Years Next Spring
And even sooner, we'll see the next expansion: Reign of the Black Empire
Tarik Muharemović: We have to be ready
Centre-half Tarik Muharemović has settled into life as a Leeds United player impressively, starring in the heart of defence as Daniel Farke’s side have remained unbeaten in the first three matches ...
Mental Health in the Age of Artificial Intelligence
The research findings encourage us to pay attention to our own well-being and our relationship with digital tools when using artificial intelligence.
Why Wild Blueberries Stand Out for Heart, Gut, and Brain Health Benefits
A new study claims that wild blueberries are powerhouse when it comes to brain, heart, and gut health—here’s what experts have to say.
Germany’s Political Tailspin: Your Weekly SPIEGEL Recap
It might be tempting to dismiss the results of last Sunday’s state election in Saxony-Anhalt, in which the far-right Alternative for Germany (AfD) party raked in 43.8 percent of the vote, as a rather unimportant extremist blip in a state that hardly anyone can find on the map. And you wouldn’t necessarily be wrong to do so. The state’s population – around 2.1 million – is a mere 2.5 percent of the German total. And while the state capital of Magdeburg was once the political heart of the Holy Roman Empire back when Otto the Great used to hang out there (more than a millenium … no … milennium … nope … millennium ago), it is today something of a backwater, albeit one with a ginormous cathedral in its center. We wanted to briefly interrupt this week’s newsletter to extend a heartfelt thank you to all of our subscribers, both new and old. And to remind you all that a free subscription gets you access to this newsletter every Saturday. A paid subscription, by contrast, gets you one DER SPIEGEL article every weekday, delivered to your inbox. We strive to select pieces that both demonstrate what Europe’s leading newsmagazine has to offer and provide an international audience – namely, you – with an insight into how Germany and Europe view the world. If you haven’t already signed up for a paid subscription, please consider doing so if you can. Our Substack channel relies entirely on reader support and we are excited to continue offering you the best of DER SPIEGEL. Subscribe But even beyond the fact that a huge percentage of the voters in the state decided to place an X next to a party with an ideological lineage that runs rather directly back to the right-wing extremist soup out of which the Nazi Party was born, the results are a perfect example of a phenomenon that has been plaguing German elections in recent years: the lack of an obvious path to a majority. Call it the Balkanization of German politics. There are a number of developments driving the phenomenon, but for the purposes of this newsletter, here are two of the most salient: Persistent voter frustration with the country’s two (former) big-tent parties – the Christian Democrats (CDU) on the center-right (17.2 percent in Saxony-Anhalt last Sunday) and the Social Democrats (SPD) on the center-left (9.3 percent). The presence of parties on the far left (Left Party), the populist left (the Sahra Wagenknecht Alliance – BSW) and the far right (AfD) with which mainstream parties are reluctant to form coalitions. So what happens now? Stories of the Week A Lack of Leadership The answer for many people in the country, and particularly within the CDU, is clear: pin (some of) the blame on Chancellor Friedrich Merz. According to a survey taken directly after the election in Saxony-Anhalt, 88 percent of respondents agreed with the statement that if the federal government in Berlin were doing a better job, the AfD wouldn’t be as strong. And it is true that the predominant impression of the federal government ever since Merz was sworn in on May 6, 2025, is one of ineffectiveness and bickering. His rather unique combination of bumbling-plus-bravado has also not exactly endeared him to the German public. Indeed, his standing in the country is so shaky that his popularity – according to recent polls – has now dropped even below the historic lows associated with his predecessor Olaf Scholz. The situation is such that the CDU even opted to keep him largely out of the campaign ahead of the Saxony-Anhalt vote. And since then, dissatisfied rumblings within the CDU have grown louder. DER SPIEGEL’s Swantje Karich notes that the problems with the CDU go much deeper than Merz. “The center-right has a trust problem. At a press appearance following the devastating election result in Saxony-Anhalt, Friedrich Merz said that the party wanted to ‘reach people more effectively’ through ‘emotional engagement.’ It sounded as though he were announcing a political program. On the basis of that statement, it is difficult to take his empathy seriously.” “The Chancellor’s chastened appearance did, at least, reveal where he stands: with his back to the wall. Elections will be held in Mecklenburg-Western Pomerania next week, and the CDU could fare even worse there. The party is polling at between 8 and 10 percent in the state.” “What is at stake is the political tradition that has lent stability to the Federal Republic since 1945: a democratic conservatism that understands what must be preserved, but also how to embrace progress and openness to the world. If the Union continues along its current path, it risks becoming politically irrelevant after the 2029 federal election – and Germany could soon find itself with a government of the far right.” The Trumpification of Political Debate? It is often said in Germany that to understand the political and social trends that will soon be dominant in Europe, one need only look across the Atlantic to the United States. When it comes to political debate, that has certainly proven true. Donald Trump understood early on that triggering mouth-foaming outrage among Democrats is an ideal way to both generate headlines and to secure loyalty among supporters. And he realized that far more quickly than the left side of the political spectrum understood that simply ignoring the old man might be the best recipe. To be sure, there have been signs recently that the US president may be over-relying on the strategy. Earlier this week, in an apparent grandpa-discovers-AI moment, Trump sent out 60 posts in the space of 10 hours, many of them AI-assisted images portraying him as a hero – or showing Iceland as part of the US (outrageous!!!). It was also during that slew of schlock that he explicitly backed the AfD with an “MGGA” post. In Germany, though, the outrage cycle remains in full swing, with much of the focus on those who would dare to vote for the AfD. They are alternately portrayed as being dim-witted, ungrateful, backward, racist or all of the above. That, argues DER SPIEGEL columnist Sabine Rennefanz, is not particularly helpful. “Everywhere on election night, people spoke of a watershed moment, a rupture, a turning point. But what is that supposed to mean in concrete terms? A watershed would imply an interruption, a moment of pause – perhaps even a willingness to rethink and learn. At first, there was little sign of that in the main television panels. Instead, the familiar rituals that had already shaped the election campaign continued: outrage, lecturing and abuse.” “That’s just the tone, one might object. They’re only talk shows. Given that the party’s state branch has been classified by domestic intelligence officials as confirmed right-wing extremist, there are more important problems than hurt feelings on television. Yet although the condescending tone is not the cause of the AfD’s success, it is an expression of the broader mood within the so-called political center – a kind of institutional blindness that too often treats material concerns as a communications problem.” “People have a pretty good sense of whether you like them – whether you approach them with curiosity or merely study, lecture and manage them as a problem group. They notice whether you genuinely want to understand their fears and pain, or whether you are simply waiting for the chance to correct them. They can also tell whether someone still has the energy to change things, or whether they have barricaded themselves behind platitudes and empty phrases.” “Anyone who wants an egalitarian democratic society cannot promise equality only to those whose language, tastes and moral convictions they share. They must also acknowledge the wounds, resentments and fears of those whose political conclusions they consider wrong. Acknowledging them does not mean agreeing with them. But a democracy that communicates with almost half its citizens only through warnings and labels gives up on political debate before it has even begun. An atmosphere must be created in which people can express their opinions without fearing that they will be canceled. We are currently a long way from that.” East-West? One of the clear undercurrents in the election last Sunday was, of course, Germany’s ongoing east-west divide, particularly as it pertains to the success of the AfD. Historically, the party has been far stronger in the former East German states than in former West German states. The fact that this generalization no longer reliably holds is certainly one of the primary concerns that many have about the party’s growth. And yet, there is still a distinct flavor of “stupid easterners, they don’t understand democracy” to the coverage. In the weeks before the vote, there was even a rather interesting back-and-forth in Germany’s culture pages about how ungrateful eastern Germans allegedly are for being pulled out of their pre-reunification backwardness and into the light of the West. DER SPIEGEL’s Jochen-Martin Gutsch has had enough. “Ten years ago, in 2016, elections were also held in Saxony-Anhalt. The AfD won more than 20 percent, which at the time rightly provoked outrage and incomprehension in western Germany. Today, in 2026, the AfD is also polling at around 20 percent in western German states, but this no longer provokes outrage and incomprehension. Instead, it is now regarded as proof of democratic conviction and civilizational resistance. After all, in the east, it’s 40 percent!” “This allows people to continue feeling morally superior to the East, but the wiser course would be to admit: if something doesn’t happen soon, the West will turn AfD-blue too. Or bluish.” “But will anything happen? The truly depressing thing about election night was not so much the AfD leaders intoxicated by their own success. It was the representatives of the other parties, who once again said that they were utterly shocked, needed some time to digest the result and would, of course, not simply return to business as usual. The SPD, a former big-tent party, celebrated its ‘stable’ result of 9.3 percent. Congratulations!” “For 10 years, the AfD has gone from one electoral success to the next. And still, the established parties remain ‘shocked’ and scratch their heads in astonishment. How long can they keep being shocked? Friedrich Merz says he may need to communicate his reform ideas in a more ‘emotional’ way. So the CDU’s political professionals sit down together after the election, mull over a strategy, and in the end come up with this: Fritz, try to be a little more relaxed, charismatic and emotional – or something. Beyond that: no political plan, no defiance, no promise of a future. That is frightening.” What was good, what was bad for democracy? Good: Voter turnout in Saxony-Anhalt was 77.8 percent, the highest ever recorded in the state. Whatever one thinks of the result, that figure is encouraging. Democracy needs citizens to take an interest. Bad: Although a strong AfD result had been expected in Saxony-Anhalt, many politicians from the mainstream parties – including in Berlin – appeared confused, helpless and overwhelmed in their initial reactions. That is not how they will win back voters’ trust. Last Week’s Highlights: 🗳️ Meet the Germans Who Voted for the AfD: Why would voters in a country like Germany, with its Nazi past, vote for a right-wing party? It’s a question only an editor in Berlin could come up with. On the ground, the view is different. 🟦 How the AfD Wants to Expand Its Power Across Germany: The far-right AfD is planning to decimate public broadcasting in Saxony-Anhalt, revamp education and install extremists in positions of power. And it is eyeing victory on the national stage as well. 🕯️ The Continuing Reverberations of September 11: It was a generational shock, and the consequences can still be felt today - from massive surveillance and significant increases in presidential power to violent excesses at ICE. 🤝 “For Europe, Canada Is the Preferred Partner in Trans-Atlantic Relations”: In an interview with DER SPIEGEL, Canadian Finance Minister François-Philippe Champagne discusses his country’s failed trade deal with the US and why Canada is looking to Europe. 🏛️ The True Historical Roots of the AfD: During the Weimar Republic in the 1920s, there were numerous parties on the extreme right espousing “Germany first” nationalism. The Nazis may not be the best comparison for today’s AfD. 🌊 AfD in a Landslide: Merz Is the Wrong Leader for Germany: The right-wing Alternative for Germany won in a landslide in Saxony-Anhalt state elections on Sunday. What does that mean for the country at large? Thank you for your continued support and have a wonderful week! Subscribe Share Leave a comment Your SPIEGEL Substack Team Compiled and edited by Charles Hawley
Wayne Youngquist, popular local TV political analyst for years, dies
Youngquist, an academic at heart, was on the cutting edge of polling and projecting winners on election nights, especially for a local TV station.
Phoenix Suns Still Banking on Khaman Maluach Leap
The seven-foot prodigy eyes a breakout role, wielding elite rim protection and perimeter range to potentially overtake veteran starters as the defensive heartbeat of Phoenix’s rising rotation.
Northern Wisconsin high school cancels remainder of football season
FLORENCE COUNTY, Wis. (WFRV) — The Bobcats, Florence County School District’s football team, have had their season cut short due to a combination of unforeseen circumstances. According to a social media post, the decision stemmed from a lack of available players. “It is with a heavy heart we inform you of a difficult decision regarding […]
‘Our hearts are broken’: NOTO Arts & Entertainment District speaks out on shooting that left two dead
TOPEKA (KSNT) – Officials representing the NOTO Arts & Entertainment District have released a statement following a recent deadly shooting in north Topeka. Officials with the NOTO Arts & Entertainment...
‘Our hearts are broken today’: NOTO Arts sends condolences after double homicide in North Topeka
The NOTO Arts & Entertainment District has released a statement following a double homicide that occurred in the area on Thursday.
Scientists discover a new way a disease-linked protein comes apart
Transthyretin amyloid disease (ATTR) is a progressive, life-threatening condition caused when the protein transthyretin (TTR) breaks apart and aggregates in the heart and other organs. One of the most ...
Hormone therapy for menopause might have heart health benefits
Hormone therapy may do more than ease hot flashes and night sweats. A new study suggests it may also be linked to a lower risk of heart problems.
How Did a Heart Drug With So Much Promise Fall So Flat?
Cardiologists are struggling to figure out why a drug that should have prevented heart attacks didn’t work at all.
Defining His Race: How a Charlotte Motorsports Leader Found a New Heart and a Second Chance
After experiencing subtle symptoms one Easter weekend, Charlotte Motor Speedway President and General Manager Greg Walter suffered a massive heart attack that led to cardiac arrest, advanced life support, and a heart transplant at Atrium Health Sanger Heart & Vascular Institute. Today, Greg is back at the track with a renewed perspective on life, leadership and recovery.
Vice Chair of Health Care leads year-round campaign to improve health in the Twin Cities
MINNEAPOLIS, Mn – Aug. 11, 2026 — Through the American Heart Association’s Heart of Minneapolis campaign, Jon Salveson, volunteer chair and vice chair of health care for Piper Sandler, will lead community-wide efforts to help ensure every individual in...
Too much light at night may quietly reshape your heart
Nighttime light exposure was linked to thicker, stiffer heart chambers and early signs of reduced heart function in a study of more than 11,000 people. The findings suggest that keeping bedrooms darker could be an overlooked strategy for protecting the heart.
The best recent science fiction, fantasy and horror
Massif by Garth Nix; Revolution in the Heart: Stories Inspired By Ursula K Le Guin edited by Jonathan Strahan; An Immaculate Deception by Isabela Livino; Serenity Falls by CJ Tudor
An AI tool aims to catch harder-to-detect heart attacks in EKGs
A newly approved AI tool can scan EKGs for severe heart attacks and, the company says, for rarer patterns indicating blocked arteries.
Metroid Dread Dev MercurySteam Seemingly Confirms Work On Ravenous With Ninja And Love Heart Emojis
🥷❤️😊
How Heart Disease Can Start as Early as Your 20s
A major new study found plaque in some adults under 30, suggesting that protecting the heart may need to begin decades before symptoms appear.
Heart damage may occur from getting too much light at night, study finds
Darkness should be recognized as one of the vital signs for health, researchers suggest.
Study finds light exposure during sleep may affect heart health
A new study suggests that exposure to light during sleep, even at low levels, may negatively impact heart health.
Study finds light exposure during sleep may affect heart health
A new study suggests that exposure to light during sleep, even at low levels, may negatively impact heart health.
New economic tool helps planners consider urban public health impacts
Senior urban development decision-makers have revealed there is currently little incentive to consider public health impacts when shaping towns and cities, according to a new study that highlights the potential of an innovative economic valuation tool to address the problem.
Hearts 'have to be above emotions' as big favourites
Hearts head coach Wouter Vrancken insists there can be no excuses as his side prepare to face Stenhousemuir at Ochilview on Friday with a place in the Premier Sports Cup semi-finals at stake.
For Heart Health Day St. Mary Medical Center is hosting a free community health fair
St. Mary Medical Center is hosting a free community health fair for Heart Health Day.
For Heart Health Day St. Mary Medical Center is hosting a free community health fair
St. Mary Medical Center is hosting a free community health fair for Heart Health Day.
Children’s health at risk in south Borneo as El Niño intensifies Indonesia wildfires
BANJARMASIN, Indonesia — Siti Sarah slept in fits and starts through August as the fires broke out around her village and surrounding peatlands. One fire on Aug. 18 at first seemed a safe distance away, but in a heartbeat the flames were within 100 meters (330 feet) of her home in Pengayuan, a village in […]
Healthy Moms, Healthy Babies pledges $100M to cut US maternal mortality rate in half
Healthy Moms, Healthy Babies America, the bipartisan campaign founded by Olivia and Tom Walton’s nonprofit Heartland Forward, announced a $100 million pledge Thursday to make giving birth in the United States safer.
Hormone Therapy For Menopause Might Have Heart Health Benefits
By Dennis Thompson HealthDay ReporterTHURSDAY, Sept. 10, 2026 (HealthDay News) — Hormone therapy started during menopause might reduce a woman’s risk of heart attack and stroke, a new study says. For common menopause symptoms such as hot flashes and night sweats, which affect as many as 80% of ...
How A Cardiologist Eats Eggs For ‘Amazing Protein’ And Heart Health
In TODAY.com’s Expert Tip of the Day, a cardiologist reveals how he prepares eggs, what he eats with them and which additions he avoids. “I fill myself. I eat like a machine,” he says.
American Heart Association PREVENT equations now integrated into national electronic health record platform
DALLAS, Thurs., Sept. 10 — The American Heart Association Predicting Risk of cardiovascular disease EVENTs™ (PREVENT) equations are now integrated into Epic's electronic health record (EHR) platform, making modern cardiovascular risk assessment now...
Oz says ‘AI-based avatars’ can help rural communities. Some leaders disagree
Feds invest in AI for heart failure, vaccines and this year's midterms, and more health news from Morning Rounds
When music becomes eternal: InConcert Sierra’s 80th anniversary begins
There are sounds that are beautiful. And then there are sounds that seem to reach somewhere beyond words—sounds that quiet the mind, stir the heart and leave you changed, even
Niko Tsakris flashes class as San Jose rekindle winning ways
By Ben SteinerIf absence makes the heart grow fonder, then Niko Tsakris's return to the scoresheet must have felt pretty sweet on Wednesday night.Guiding the San Jose Earthquakes to a 3–2 win over C...
Spanish Grand Prix 2026: Can football-obsessed Madrid embrace F1?
After F1’s explosion in popularity away from its European heartland the sport is coming home. Why Madrid? Because it is beautiful… and has a very big expo centre on the outskirts.
Parma elementary student wins Super Bowl tickets after completing a heart health challenge
A Parma City Schools first-grader walked into what she thought was a school assembly and walked out with tickets to the Super Bowl.
The Apple Watch Ultra 4 Is an Even Better Heart Health Companion
Apple's high-end smartwatch also comes with the new internals of the Apple Watch Series 12 and even longer battery life.
Apple Announces Apple Watch Series 12 With S11 Chip, Upgraded Health Sensors and Ceramic Models
Apple today announced the Apple Watch Ultra 4, featuring a new S11 chip, a redesigned health sensing system, and a larger battery that Apple says delivers two days of battery life. With improved power efficiency, Ultra 4 offers up to 18 hours of workout tracking with full GPS and heart rate monitoring, or 45 hours in its maximum extended workout mode. It comes in Black and Natural titanium, alongside new band colors and a new titanium Hermès band.
ACC Latin America 2026 brings together experts to examine the latest cardiovascular science
The American College of Cardiology (ACC) and the Colombian Society of Cardiology and Cardiovascular Surgery will host the ACC Latin America 2026 conference on September 17-19 in Medellín, Colombia.
ARPA-H to invest $62 million to develop FDA-authorized AI to help treat heart failure
ARPA-H, the government agency that funds cutting edge health research, plans to commit $62.7 million to develop artificial intelligence bots that direct
Vrancken has captured imagination of Hearts fans
There was a sense of inevitability about Hearts' late winner against Dundee on Sunday. Much of the credit for Hearts' recent form must go to Wouter Vrancken. The Belgian's style of play has captured the imagination of the Hearts support and, just as importantly, the players have fully embraced his football philosophy.
Huge Steam Leak Spoils ‘Kingdom Hearts 4,’ ‘Persona 6’ And More
On Wednesday morning, Steam suffered one of its worst leaks in recent memory affecting Kingdom Hearts 4, Persona 6 and many others.
Persona 6, Kingdom Hearts 4 spoilers may have emerged online amid massive achievements leak for unreleased games
An apparent Steam leak has resulted in a large number of achievement details for upcoming games appearing online.
Apparent Steam Leak Reveals Persona 6 and Kingdom Hearts 4 Achievements, Unannounced Games
Achievements for various upcoming games have been made public as part of a significant Steam leak.
Germany must relearn the language of power-politics
To protect Europe from Russian aggression, Germans must resolve a tension that lies the heart of their modern national identity: a clash between the ideals of ‘Never Again Fascism’ and ‘Never Again Germany’.
Napoli v Arsenal Preview: Gunners Begin Another Champions League Quest
Arsenal begin another Champions League campaign on Wednesday night with a difficult trip to Napoli, looking to take the first step towards going one better after the heartbreak of last season’s fina...
Kingdom Hearts 4's Disney Worlds May Have Been Revealed By Massive Steam Leak
The achievement database Exophase has listed achievements for several games, including some that haven't been announced
Baton Rouge General's Health Tip of the Week: Another sugar substitute raises heart concerns
Sponsored by Baton Rouge General Cutting back on sugar? Take a peek at the ingredient label before reaching for a sugar-free treat. Recent research has raised questions about xylitol, a sugar alcohol found in products like gum, candy and baked goods. Higher blood levels of xylitol were linked to a greater risk of heart attack […]
Major Kingdom Hearts 4 leak surfaces, new worlds revealed
New worlds have just been revealed for Kingdom Hearts 4 as part of a major leak for the game.
Persona 6, Kingdom Hearts IV, and other Steam Achievements surface in large-scale leak
Steam Achievement lists for major titles like Persona 6 and Kingdom Hearts IV have surfaced on Exophase, a site that specializes in trophy and achievement tracking.
Why Lewis Dunk Is STILL Brighton's Most Underrated Player
The veteran skipper remains the common denominator in Brighton’s success, transforming raw defensive partners into stars while proving he is the timeless heartbeat of the Seagulls’ backline.
Smithsonian chief Lonnie Bunch to retire following clash with Trump admin
Bunch said in a news release Tuesday that he was departing the position he had held since 2019 "with very mixed emotions and heartfelt gratitude"
Smithsonian chief Lonnie Bunch to retire following clash with Trump admin
Bunch said in a news release Tuesday that he was departing the position he had held since 2019 "with very mixed emotions and heartfelt gratitude"
Smithsonian chief Lonnie Bunch to retire following clash with Trump admin
Bunch said in a news release Tuesday that he was departing the position he had held since 2019 "with very mixed emotions and heartfelt gratitude"
Mercy health fair brings vital medical checkups and nutritional aid to Heartland families
The event is designed to provide critical medical screenings, vaccinations, and wellness resources to Heartland families.
Celebrating 19 Years of Impact from One Iconic Desk
For nearly two decades, Administrative Assistant Carolina Rodriguez has been one of the first faces people see and one they remember at South Texas College’s (STC) Mid-Valley Campus. Long before titles or job descriptions, she became something harder to define but easy to feel: a constant presence, a listening ear and the heart of the campus.
The Row brings new retail, dining and entertainment to Heartwood
The Row, a new in-line retail center located in Poplar Place within Heartwood’s Town District, will bring a growing mix of dining, entertainment, services and specialty retail to one of the community’s most visible commercial areas at Exit 82.
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
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